PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
8605985-5	1996	The corticosteroid prednisolone-21-hemisuccinate was found to inactivate bovine liver catalase, in vitro in a progressive manner.	prednisolone hemisuccinate	19-48	catalase	Bos taurus	86-94
10822092-1	2000	We have investigated the effects of prednisolone sodium succinate (Pss) and cyclosporin A (CSA), applied alone or concurrently, on the release of arachidonic acid (AA) (cytosolic phospholipase A(2) (cPLA(2)) activity) and on the calcineurin (CN) activity of human peripheral blood mononuclear cells (PBMC).	prednisolone hemisuccinate	36-65	phospholipase A2 group IVA	Homo sapiens	169-206
10822092-1	2000	We have investigated the effects of prednisolone sodium succinate (Pss) and cyclosporin A (CSA), applied alone or concurrently, on the release of arachidonic acid (AA) (cytosolic phospholipase A(2) (cPLA(2)) activity) and on the calcineurin (CN) activity of human peripheral blood mononuclear cells (PBMC).	prednisolone hemisuccinate	67-70	phospholipase A2 group IVA	Homo sapiens	169-206
10822092-3	2000	We found that Pss (10(-5) M) could inhibit the CN activity and higher concentrations (10(-4) M) could decrease the cytotoxic damage caused by CSA (10(-4) M) during their combined application.	prednisolone hemisuccinate	14-17	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	142-145
9540854-0	1997	Inactivation of glyceraldehyde 3-phosphate dehydrogenase by sugars, prednisolone-21-hemisuccinate, cyanate and other small molecules.	prednisolone hemisuccinate	68-97	LOC786101	Bos taurus	16-56
9540854-7	1997	In-vitro incubations of GAP-DH with sugars, cyanate and prednisolone-21-hemisuccinate, all led to significant loss of enzyme activity with time in two buffer systems.	prednisolone hemisuccinate	56-85	LOC786101	Bos taurus	24-30
9540854-8	1997	Rapid inactivation occurred when GAP-DH was incubated with fructose 6-phosphate or prednisolone-21-hemisuccinate.	prednisolone hemisuccinate	83-112	LOC786101	Bos taurus	33-39
8933206-10	1996	Stimulation with a sonicated B. burgdorferi preparation in the presence of the water-soluble compound Prednisolone-21-hemisuccinate considerably reduced expression of ICAM-1, and marginally also of E-selectin, whereas the level of P-selectin and VCAM-1 remained unaltered.	prednisolone hemisuccinate	102-131	intercellular adhesion molecule 1	Mus musculus	167-173
8933206-10	1996	Stimulation with a sonicated B. burgdorferi preparation in the presence of the water-soluble compound Prednisolone-21-hemisuccinate considerably reduced expression of ICAM-1, and marginally also of E-selectin, whereas the level of P-selectin and VCAM-1 remained unaltered.	prednisolone hemisuccinate	102-131	selectin, endothelial cell	Mus musculus	198-208
8933206-10	1996	Stimulation with a sonicated B. burgdorferi preparation in the presence of the water-soluble compound Prednisolone-21-hemisuccinate considerably reduced expression of ICAM-1, and marginally also of E-selectin, whereas the level of P-selectin and VCAM-1 remained unaltered.	prednisolone hemisuccinate	102-131	vascular cell adhesion molecule 1	Mus musculus	246-252
7398044-2	1980	The antiserum produced in rabbits to prednisolone-21-hemisuccinate/bovine serum albumin was specific for prednisolone and prednisolone-21-hemisuccinate.	prednisolone hemisuccinate	37-66	albumin	Oryctolagus cuniculus	74-87
7398044-2	1980	The antiserum produced in rabbits to prednisolone-21-hemisuccinate/bovine serum albumin was specific for prednisolone and prednisolone-21-hemisuccinate.	prednisolone hemisuccinate	122-151	albumin	Oryctolagus cuniculus	74-87
4433653-0	1974	Enhanced response of erythropoietin sensitive cells to erythropoietin by low dose prednisolone hemisuccinate and its abolition by azathioprine.	prednisolone hemisuccinate	82-108	erythropoietin	Homo sapiens	21-35
4433653-0	1974	Enhanced response of erythropoietin sensitive cells to erythropoietin by low dose prednisolone hemisuccinate and its abolition by azathioprine.	prednisolone hemisuccinate	82-108	erythropoietin	Homo sapiens	55-69
21109752-6	2011	Basophils from one patient exhibited a stimulated expression of the activation marker CD63 upon in vitro incubation with PSH or hydrocortisone sodium succinate, but not with hydrocortisone.	prednisolone hemisuccinate	121-124	CD63 molecule	Homo sapiens	86-90
11315771-0	2001	Prednisolone sodium succinate down-regulates BSAP/Pax5 and causes a growth arrest in the Nalm6 pre-B cell line.	prednisolone hemisuccinate	0-29	paired box 5	Homo sapiens	45-49
11315771-0	2001	Prednisolone sodium succinate down-regulates BSAP/Pax5 and causes a growth arrest in the Nalm6 pre-B cell line.	prednisolone hemisuccinate	0-29	paired box 5	Homo sapiens	50-54
11315771-2	2001	Since B cell-specific activator protein (BSAP) encoded by the Pax5 gene is an essential transcription factor for B-cell proliferation, we have investigated the effect of prednisolone sodium succinate (Pss) on BSAP expression in several human leukemic B lineage cell lines.	prednisolone hemisuccinate	170-199	paired box 5	Homo sapiens	209-213
11315771-2	2001	Since B cell-specific activator protein (BSAP) encoded by the Pax5 gene is an essential transcription factor for B-cell proliferation, we have investigated the effect of prednisolone sodium succinate (Pss) on BSAP expression in several human leukemic B lineage cell lines.	prednisolone hemisuccinate	201-204	paired box 5	Homo sapiens	209-213
11315771-4	2001	In Nalm6 cells, the growth rate and the amount of BSAP bound to its recognition sequence decreased in proportion to the Pss dose.	prednisolone hemisuccinate	120-123	paired box 5	Homo sapiens	50-54
11315771-5	2001	Pss also reduced the expression level of BSAP as well as of Pax5 mRNA.	prednisolone hemisuccinate	0-3	paired box 5	Homo sapiens	41-45
11315771-5	2001	Pss also reduced the expression level of BSAP as well as of Pax5 mRNA.	prednisolone hemisuccinate	0-3	paired box 5	Homo sapiens	60-64
7667198-2	1995	METHODS: A dose of CBG to yield 95% binding with 1000 ng/ml of prednisolone in vitro in rat plasma or saline was administered before dosing 2 mg/kg of prednisolone hemisuccinate or methylprednisolone intravenously.	prednisolone hemisuccinate	151-177	serpin family A member 6	Rattus norvegicus	19-22