PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21297378-0	2011	5-Formylhonokiol exerts anti-angiogenesis activity via inactivating the ERK signaling pathway.	5-formylhonokiol	0-16	mitogen-activated protein kinase 1	Homo sapiens	72-75
21297378-10	2011	Furthermore, western blotting showed that 5-formylhonokiol significantly down-regulated extracellular signal-regulated kinase (ERK) expression and inhibited the phosphorylation of ERK but not affecting the total protein kinase B (Akt) expression and related phosphorylation, suggesting that 5-formylhonokiol might exert anti-angiogenesis capacity via down-regulation of the ERK signal pathway.	5-formylhonokiol	42-58	mitogen-activated protein kinase 1	Homo sapiens	88-125
21297378-10	2011	Furthermore, western blotting showed that 5-formylhonokiol significantly down-regulated extracellular signal-regulated kinase (ERK) expression and inhibited the phosphorylation of ERK but not affecting the total protein kinase B (Akt) expression and related phosphorylation, suggesting that 5-formylhonokiol might exert anti-angiogenesis capacity via down-regulation of the ERK signal pathway.	5-formylhonokiol	42-58	mitogen-activated protein kinase 1	Homo sapiens	127-130
21297378-10	2011	Furthermore, western blotting showed that 5-formylhonokiol significantly down-regulated extracellular signal-regulated kinase (ERK) expression and inhibited the phosphorylation of ERK but not affecting the total protein kinase B (Akt) expression and related phosphorylation, suggesting that 5-formylhonokiol might exert anti-angiogenesis capacity via down-regulation of the ERK signal pathway.	5-formylhonokiol	42-58	mitogen-activated protein kinase 1	Homo sapiens	180-183
21297378-10	2011	Furthermore, western blotting showed that 5-formylhonokiol significantly down-regulated extracellular signal-regulated kinase (ERK) expression and inhibited the phosphorylation of ERK but not affecting the total protein kinase B (Akt) expression and related phosphorylation, suggesting that 5-formylhonokiol might exert anti-angiogenesis capacity via down-regulation of the ERK signal pathway.	5-formylhonokiol	42-58	mitogen-activated protein kinase 1	Homo sapiens	180-183