PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
24143955-4	2013	Unlike known SUMOylation inhibitors such as ginkgolic acid, spectomycin B1 directly binds to E2 (Ubc9) and selectively blocks the formation of the E2-SUMO intermediate; that is, Ubc9 is the direct target of spectomycin B1.	Spectomycin B1	60-74	ubiquitin conjugating enzyme E2 I	Homo sapiens	97-101
24143955-4	2013	Unlike known SUMOylation inhibitors such as ginkgolic acid, spectomycin B1 directly binds to E2 (Ubc9) and selectively blocks the formation of the E2-SUMO intermediate; that is, Ubc9 is the direct target of spectomycin B1.	Spectomycin B1	60-74	ubiquitin conjugating enzyme E2 I	Homo sapiens	178-182
24143955-4	2013	Unlike known SUMOylation inhibitors such as ginkgolic acid, spectomycin B1 directly binds to E2 (Ubc9) and selectively blocks the formation of the E2-SUMO intermediate; that is, Ubc9 is the direct target of spectomycin B1.	Spectomycin B1	207-221	ubiquitin conjugating enzyme E2 I	Homo sapiens	178-182
24143955-6	2013	Our findings suggest that Ubc9 inhibitors such as spectomycin B1 have potential as therapeutic agents against hormone-dependent breast cancers.	Spectomycin B1	50-64	ubiquitin conjugating enzyme E2 I	Homo sapiens	26-30