PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 9178190-3 1997 Some hydroxychalcone derivatives showed strong inhibitory effects on the release of beta-glucuronidase and lysozyme, and on superoxide formation by rat neutrophils stimulated with the peptide fMet-Leu-Phe (fMLP). hydroxychalcone 5-20 glucuronidase, beta Rattus norvegicus 84-102 28655421-1 2017 A series of hydroxychalcone derivatives have been designed, synthesized and evaluated for human xanthine oxidase (XO) inhibitory activity. hydroxychalcone 12-27 xanthine dehydrogenase Mus musculus 96-112 21222511-0 2011 Design, synthesis and SAR study of hydroxychalcone inhibitors of human beta-secretase (BACE1). hydroxychalcone 35-50 beta-secretase 1 Homo sapiens 87-92 15596260-11 2005 In summary, the present study illustrated that the inhibition of hydroxychalcone on CYP1 enzymes and XRE-transactivation was affected by the position and number of hydroxyl groups in its structure. hydroxychalcone 65-80 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 84-88