PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 29184140-7 2017 RhoGAP depletion mimicked these MTI-mediated processes. CHEMBL473929 32-35 Rho GTPase activating protein 1 Homo sapiens 0-6 19154728-6 2009 When cell lysate was treated with and without MTI, tacrolimus and FKBP12, FKBP12 could increase calcineurin inhibition by tacrolimus and reverse the MTI antagonism for both MTIs. CHEMBL473929 46-49 FKBP prolyl isomerase 1A pseudogene 2 Homo sapiens 74-80 19154728-6 2009 When cell lysate was treated with and without MTI, tacrolimus and FKBP12, FKBP12 could increase calcineurin inhibition by tacrolimus and reverse the MTI antagonism for both MTIs. CHEMBL473929 149-152 FKBP prolyl isomerase 1A pseudogene 2 Homo sapiens 66-72 19154728-6 2009 When cell lysate was treated with and without MTI, tacrolimus and FKBP12, FKBP12 could increase calcineurin inhibition by tacrolimus and reverse the MTI antagonism for both MTIs. CHEMBL473929 149-152 FKBP prolyl isomerase 1A pseudogene 2 Homo sapiens 74-80 17942929-8 2007 TSLP also partially reverses the effects of MTI on proliferation, apoptosis, and ribosomal protein S6 and 4E-BP1 phosphorylation in cell lines, with similar biological effects seen in some primary human lymphoblast samples. CHEMBL473929 44-47 thymic stromal lymphopoietin Homo sapiens 0-4 17942929-10 2007 These findings suggest that IL-7Ralpha chain is responsible for transducing the survival signal that overcomes MTI-mediated growth inhibition in pre-B ALL. CHEMBL473929 111-114 interleukin 7 receptor Homo sapiens 28-38 16501580-10 2006 reduced by 50% of the maximum possible efficacy (MPE) mechanical allodynia induced by MTI in FAAH(+/+)mice (von Frey filament measurement) 30 min after dosing, but was without effect in FAAH(-/-) mice. CHEMBL473929 86-89 fatty acid amide hydrolase Mus musculus 93-97 27688725-9 2016 Routine analysis of mTOR activity could be performed to select patients that may potentially benefit from mTOR inhibitors (MTI) treatment. CHEMBL473929 123-126 mechanistic target of rapamycin kinase Homo sapiens 20-24 27688725-9 2016 Routine analysis of mTOR activity could be performed to select patients that may potentially benefit from mTOR inhibitors (MTI) treatment. CHEMBL473929 123-126 mechanistic target of rapamycin kinase Homo sapiens 106-110