PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 23273201-1 2012 MTHFR is a key enzyme in folate metabolism that catalyzes the conversion of 5, 10—methlenetetrahydrofolate (5, 10— methylene THF) to 5—methyltetrahydrofolate (5—methyl THF), a predominant circulatory form of folate and methyl donor for the remethylation of homocysteine to methionine. 5-Methyl THF 201-211 methylenetetrahydrofolate reductase Homo sapiens 0-5 7771463-14 1995 Methyl-THF also neutralized MTX in pernicious anemia, but its effect was certainly enhanced by addition of CN-Cbl. 5-Methyl THF 0-10 Cbl proto-oncogene Homo sapiens 110-113 29882091-2 2018 PURPOSE: To evaluate the possibility of correcting metabolic defects in gametes and embryos due to methylene tetra hydrofolate reductase (MTHFR) isoforms C677T and A1298C, by supplementation with 5-methyl THF instead of synthetic folic acid. 5-Methyl THF 196-208 methylenetetrahydrofolate reductase Homo sapiens 99-136 29882091-2 2018 PURPOSE: To evaluate the possibility of correcting metabolic defects in gametes and embryos due to methylene tetra hydrofolate reductase (MTHFR) isoforms C677T and A1298C, by supplementation with 5-methyl THF instead of synthetic folic acid. 5-Methyl THF 196-208 methylenetetrahydrofolate reductase Homo sapiens 138-143