PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9810264-5	1998	Results of this investigation indicate that compounds which inhibit C6 glial cell MAO enzyme activity or scavenge peroxide product include chlorogenic acid, (+)-catechin, taxifolin, (-)-epigallocatechin gallate (EGCG), fisetin, coenzyme Q0, curcumin, sesamol, morin, sesame oil, silymarin, green tea, ferulic acid, caffeic acid, and rutin hydrate.	Rutin hydrate	333-346	monoamine oxidase A	Rattus norvegicus	82-85
35240529-0	2022	Rutin hydrate and extract from Castanopsis tribuloides reduces pyrexia via inhibiting microsomal prostaglandin E synthase-1.	Rutin hydrate	0-13	prostaglandin E synthase	Mus musculus	86-123
35240529-8	2022	Additionally, RMSF, RMSD, Rg, and hydrogen bonds performed during MD simulations revealed that rutin hydrate (rich in CTB) bound to the mPGES-1 active site in a stable manner and thus inactivating mPGES-1.	Rutin hydrate	95-108	prostaglandin E synthase	Mus musculus	136-143
35240529-8	2022	Additionally, RMSF, RMSD, Rg, and hydrogen bonds performed during MD simulations revealed that rutin hydrate (rich in CTB) bound to the mPGES-1 active site in a stable manner and thus inactivating mPGES-1.	Rutin hydrate	95-108	prostaglandin E synthase	Mus musculus	197-204
35240529-9	2022	Therefore, it can be concluded that rutin hydrate reduces pyrexia in mice via downregulating PGE2 synthesis by inhibiting mPGES-1 activity.	Rutin hydrate	36-49	prostaglandin E synthase	Mus musculus	122-129
29214892-0	2018	Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling.	Rutin hydrate	0-13	mitogen-activated protein kinase 8	Rattus norvegicus	149-152
29214892-0	2018	Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling.	Rutin hydrate	0-13	mitogen activated protein kinase 3	Rattus norvegicus	157-163
29214892-0	2018	Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling.	Rutin hydrate	0-13	mechanistic target of rapamycin kinase	Rattus norvegicus	190-194