PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
17358097-5	2007	RESULTS: The mean area under the plasma concentration-time curves from 0 to infinity (AUC(infinity)) of (R)- and (S)-lansoprazole in recipients with the CYP3A5*1 allele were 3145 and 384 ng * h/mL, respectively, compared with 4218 and 587 ng * h/mL in recipients with the CYP3A5*3/*3 genotype.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	104-108	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	153-159
24814197-2	2014	The oxazolo[4,5-b]pyridine, (R)-18, and 4-methoxyphenylurea, (R)-47, were identified as potent and selective modulators of the alpha7 nAChR with favorable in vitro safety profiles and good oral bioavailability in mouse.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	28-32	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	127-139
23376251-1	2013	Enantiomers of 2,3-dihydro-1,4-benzodioxine derivatives possessing both thrombin and fibrinogen GPIIb/IIIa binding inhibitory activities were prepared from (R)- and (S)-glycidol as potential dual antithrombotic compounds.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	156-160	coagulation factor II, thrombin	Homo sapiens	72-80
23376251-1	2013	Enantiomers of 2,3-dihydro-1,4-benzodioxine derivatives possessing both thrombin and fibrinogen GPIIb/IIIa binding inhibitory activities were prepared from (R)- and (S)-glycidol as potential dual antithrombotic compounds.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	156-160	integrin subunit alpha 2b	Homo sapiens	96-101
22616655-6	2013	In a mixed effects model the ratio of response between (R)- and (S)-warfarin (AUC(PT((R)-warfarin)) : AUC(PT((S)-warfarin))) was 1.21 fold higher (95% CI 1.05, 1.41, P < 0.02) in subjects of VKORC1 TT genotype compared with the CC genotype.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	55-59	vitamin K epoxide reductase complex subunit 1	Homo sapiens	194-200
17988152-5	2007	Here we report studies of the reaction catalyzed by GABA-AT on (R)- and (S)-3-F-GABA.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	63-67	4-aminobutyrate aminotransferase	Homo sapiens	52-59
17358097-5	2007	RESULTS: The mean area under the plasma concentration-time curves from 0 to infinity (AUC(infinity)) of (R)- and (S)-lansoprazole in recipients with the CYP3A5*1 allele were 3145 and 384 ng * h/mL, respectively, compared with 4218 and 587 ng * h/mL in recipients with the CYP3A5*3/*3 genotype.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	104-108	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	272-278
8496909-0	1993	Mechanism-based inhibitors of prostaglandin omega-hydroxylase: (R)- and (S)-12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	63-67	cytochrome P450 4A5	Oryctolagus cuniculus	30-61
8509425-0	1993	Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	23-27	cytochrome P450 2E1	Oryctolagus cuniculus	90-109
1967551-9	1990	LU-49888 labeling of Pgp was also completely inhibited by (R)-, (S)-, and racemic desmethoxyverapamil, all with the same efficiency.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	58-62	ATP binding cassette subfamily B member 1	Homo sapiens	21-24
1522951-0	1992	Inhibition of tryptophan hydroxylase by (R)- and (S)-1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines (salsolinols).	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	40-44	tryptophan hydroxylase 1	Mus musculus	14-36
28401570-0	2017	Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[11 C]verapamil in elderly vs. young subjects.	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	88-92	ATP binding cassette subfamily B member 1	Homo sapiens	10-24
26324662-1	2015	A new type of homochiral metal-organic nanotubular structures based on metal phosphonates are reported, namely, (R)- or (S)-[M(pemp)(H2O)2][M = Co(II) (1), Ni(II) (2)] [pemp(2-) = (R)- or (S)-(1-phenylethylamino)methylphosphonate].	(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol	112-116	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	144-150