PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22104217-16	2011	CONCLUSION: Gefitinib, at the cellular level, radiosensitizes EGFR with NSCLC H358 by blocking EGFR nuclear translocation as one of its mechanisms.	ZINC78587988	78-82	epidermal growth factor receptor	Homo sapiens	62-66
29845258-4	2018	In the present study, EGFR-TKI erlotinib-sensitive H358, H322 and H441 lung cancer cells, erlotinib-moderately sensitive A549 cells, and erlotinib-insensitive HCC827 cells with EGFR-mutation (exon 19 deletion) were used to detect the mRNA and protein expression of the EMT-associated proteins E-cadherin and vimentin, and napsin A, by reverse transcription-quantitative polymerase chain reaction analysis and western blotting.	ZINC78587988	51-55	epidermal growth factor receptor	Homo sapiens	22-26
30058691-10	2018	RESULTS: The results revealed that NCI-H125 showed lowest, NCI-H226 showed moderate, while as NCI-H358 exhibited the highest expression of SIRT1.	ZINC78587988	98-102	sirtuin 1	Homo sapiens	139-144
30660770-7	2019	The inhibition by siRNA of eEF1A2 expression resulted in a slight decrease in H358-NSCLC viability.	ZINC78587988	78-82	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	27-33
25499080-4	2015	Introduction of a wild type p53 into p53 null lung cancer cell lines H1299 and H358 inhibited NF-kappaB activity, leading to the enhanced response to chemotherapeutic drugs.	ZINC78587988	79-83	tumor protein p53	Homo sapiens	28-31
25499080-4	2015	Introduction of a wild type p53 into p53 null lung cancer cell lines H1299 and H358 inhibited NF-kappaB activity, leading to the enhanced response to chemotherapeutic drugs.	ZINC78587988	79-83	tumor protein p53	Homo sapiens	37-40
25499080-4	2015	Introduction of a wild type p53 into p53 null lung cancer cell lines H1299 and H358 inhibited NF-kappaB activity, leading to the enhanced response to chemotherapeutic drugs.	ZINC78587988	79-83	nuclear factor kappa B subunit 1	Homo sapiens	94-103
22067904-9	2011	A significant (P<0.05) decrease in the lung colonisation and growth was found when mice were injected with TMPRSS4-depleated H358-derived clones, as compared with controls.	ZINC78587988	128-132	transmembrane protease, serine 4	Mus musculus	110-117
10375610-7	1999	Furthermore, stable expression of an antisense Cdk2 construct in NCI-H358 also resulted in the appearance of a marker of mucinous differentiation.	ZINC78587988	69-73	cyclin dependent kinase 2	Homo sapiens	47-51
22091388-5	2011	IGF-1R pathway activated H358 and A549 cells are sensitive to IGF-1R inhibition.	ZINC78587988	25-29	insulin like growth factor 1 receptor	Homo sapiens	0-6
22091388-5	2011	IGF-1R pathway activated H358 and A549 cells are sensitive to IGF-1R inhibition.	ZINC78587988	25-29	insulin like growth factor 1 receptor	Homo sapiens	62-68
18696232-7	2008	A metastable, reversible EMT-like transition in the NSCLC line H358 was achieved by exogenous TGFbeta, which served as a model EMT system.	ZINC78587988	63-67	IL2 inducible T cell kinase	Homo sapiens	25-28
18696232-7	2008	A metastable, reversible EMT-like transition in the NSCLC line H358 was achieved by exogenous TGFbeta, which served as a model EMT system.	ZINC78587988	63-67	IL2 inducible T cell kinase	Homo sapiens	127-130
19098985-5	2008	Likewise, RASSF1A tumor suppressor was proteolyzed by the H358 cell extract.	ZINC78587988	58-62	Ras association domain family member 1	Homo sapiens	10-17
35158284-9	2022	Further, K20 could inhibit the formation of H358 or H23 tumor colonies.	ZINC78587988	44-48	keratin 20	Homo sapiens	9-12