PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
24354753-1	2015	The objective of this study is to explore the feasibility of radioiodine treatment for cervical cancer using the early growth response (Egr-1) promoter to control sodium-iodine symporter (hNIS) gene expression.	Sodium iodine	163-176	early growth response 1	Homo sapiens	136-141
22136819-1	2011	BACKGROUND: Anaplastic thyroid carcinoma (ATC) is fatal with resistance to radiotherapy because of the loss of intrinsic human sodium iodine symporter (hNIS).	Sodium iodine	127-140	solute carrier family 5 member 5	Homo sapiens	152-156
24712572-7	2014	Accordingly, small interfering RNA inhibition of TTF1 completely abrogated the induction of human sodium-iodine symporter by mTOR inhibition.	Sodium iodine	98-111	NK2 homeobox 1	Homo sapiens	49-53
24712572-7	2014	Accordingly, small interfering RNA inhibition of TTF1 completely abrogated the induction of human sodium-iodine symporter by mTOR inhibition.	Sodium iodine	98-111	mechanistic target of rapamycin kinase	Homo sapiens	125-129
21945915-0	2011	Ghrelin potentiates TSH-induced expression of the thyroid tissue-specific genes thyroglobulin, thyroperoxidase and sodium-iodine symporter, in rat PC-Cl3 Cells.	Sodium iodine	115-128	ghrelin and obestatin prepropeptide	Rattus norvegicus	0-7
21945915-5	2011	Finally, we have determined the stimulatory effect of ghrelin on TSH-induced expression of the tissue-specific key genes involved in the synthesis of thyroid hormone: thyroglobulin, thyroperoxidase and sodium-iodine symporter.	Sodium iodine	202-215	ghrelin and obestatin prepropeptide	Rattus norvegicus	54-61
15579766-11	2004	Inhibiting Id1 mRNA expression in thyroid cancer cell lines using Id1 antisense oligonucleotides resulted in growth inhibition (P < 0.03) and decreased thyroglobulin and sodium-iodine symporter mRNA expression (P < 0.02).	Sodium iodine	173-186	inhibitor of DNA binding 1, HLH protein	Homo sapiens	11-14
15944276-6	2005	To distinguish whether the observed ICAM-1 increase was a direct effect of iodine or a consequence of the immune infiltrate, we treated mouse primary thyrocyte cultures with 0.01 mM sodium iodine and showed a 3-fold increased ICAM-1 expression.	Sodium iodine	182-195	intercellular adhesion molecule 1	Mus musculus	36-42
15944276-6	2005	To distinguish whether the observed ICAM-1 increase was a direct effect of iodine or a consequence of the immune infiltrate, we treated mouse primary thyrocyte cultures with 0.01 mM sodium iodine and showed a 3-fold increased ICAM-1 expression.	Sodium iodine	182-195	intercellular adhesion molecule 1	Mus musculus	226-232
15579766-11	2004	Inhibiting Id1 mRNA expression in thyroid cancer cell lines using Id1 antisense oligonucleotides resulted in growth inhibition (P < 0.03) and decreased thyroglobulin and sodium-iodine symporter mRNA expression (P < 0.02).	Sodium iodine	173-186	inhibitor of DNA binding 1, HLH protein	Homo sapiens	66-69
34523607-4	2021	Lee, H. Lee, and colleagues showed that oncogenic fusions were more commonly associated with invasive disease, increased expression of MAPK signaling pathway genes (ERK score), and decreased expression of the sodium-iodine symporter, which was restored by RET- and NTRK-inhibitory therapy.	Sodium iodine	209-222	ret proto-oncogene	Homo sapiens	256-259
11396709-7	2001	This is achieved by decreasing the intrathyroidal inorganic iodine concentration by down regulation of the sodium iodine symporter (NIS) and therefore permits the TPO-H202 system to resume normal activity.	Sodium iodine	107-120	thyroid peroxidase	Homo sapiens	163-166
35385113-4	2022	In this study we 1) define profiles of TH in the maternal and fetal compartments of pregnant rats in response to inhibition of the sodium-iodine symporter (NIS) by perchlorate, 2) expand inquiry previously limited to serum to include fetal thyroid gland and brain.	Sodium iodine	131-144	tyrosine hydroxylase	Rattus norvegicus	39-41
31269588-0	2019	[beta-catenin nuclear translocation represses thyroid cancer stem cells differentiating into cells with sodium-iodine symporter functional expression].	Sodium iodine	104-117	catenin beta 1	Homo sapiens	1-13
34751390-0	2022	Capsaicin restores sodium iodine symporter-mediated radioiodine uptake through bypassing canonical TSH-TSHR pathway in anaplastic thyroid carcinoma cells.	Sodium iodine	19-32	thyroid stimulating hormone receptor	Homo sapiens	103-107