PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
31334915-2	2019	Recently, we identified Bractoppin, the first small-molecule inhibitor of the BRCA1 tBRCT domain, which selectively interrupts BRCA1-mediated cellular responses evoked by DNA damage.	Bractoppin	24-34	BRCA1 DNA repair associated	Homo sapiens	78-83
31334915-2	2019	Recently, we identified Bractoppin, the first small-molecule inhibitor of the BRCA1 tBRCT domain, which selectively interrupts BRCA1-mediated cellular responses evoked by DNA damage.	Bractoppin	24-34	BRCA1 DNA repair associated	Homo sapiens	127-132
29606576-3	2018	Here, we develop Bractoppin, a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain, which selectively inhibits substrate binding with nanomolar potency in vitro.	Bractoppin	17-27	BRCA1 DNA repair associated	Homo sapiens	94-99
29606576-5	2018	In cells, Bractoppin inhibits substrate recognition detected by Forster resonance energy transfer, and diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51.	Bractoppin	10-20	BRCA1 DNA repair associated	Homo sapiens	114-119
29606576-5	2018	In cells, Bractoppin inhibits substrate recognition detected by Forster resonance energy transfer, and diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51.	Bractoppin	10-20	RAD51 recombinase	Homo sapiens	225-230