PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 31669234-5 2020 Western blot and qPCR assays results further confirmed DLF induced caspase-dependent apoptosis and inhibited PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in CRC cells. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 55-58 AKT serine/threonine kinase 1 Homo sapiens 114-117 31669234-5 2020 Western blot and qPCR assays results further confirmed DLF induced caspase-dependent apoptosis and inhibited PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in CRC cells. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 55-58 mechanistic target of rapamycin kinase Homo sapiens 118-122 31669234-5 2020 Western blot and qPCR assays results further confirmed DLF induced caspase-dependent apoptosis and inhibited PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in CRC cells. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 55-58 mitogen-activated protein kinase kinase 7 Homo sapiens 131-134 31669234-5 2020 Western blot and qPCR assays results further confirmed DLF induced caspase-dependent apoptosis and inhibited PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in CRC cells. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 55-58 mitogen-activated protein kinase 1 Homo sapiens 135-138 31669234-6 2020 Meanwhile, DLF significantly suppressed the tumor growth via activation of Caspase-9 and Caspase-3 protein and decrease of ki67 and CD34 protein without apparent side effects in vivo. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 11-14 caspase 9 Homo sapiens 75-84 31669234-6 2020 Meanwhile, DLF significantly suppressed the tumor growth via activation of Caspase-9 and Caspase-3 protein and decrease of ki67 and CD34 protein without apparent side effects in vivo. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 11-14 caspase 3 Homo sapiens 89-98 31669234-6 2020 Meanwhile, DLF significantly suppressed the tumor growth via activation of Caspase-9 and Caspase-3 protein and decrease of ki67 and CD34 protein without apparent side effects in vivo. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 11-14 CD34 molecule Homo sapiens 132-136 31669234-7 2020 In summary, these results indicated DLF induced ROS-mediated cell cycle arrest and apoptosis through ER stress and mitochondrial pathway accompanying with the inhibition of PI3K/AKT/mTOR and Ras/MEK/Erk signaling cascade. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 36-39 AKT serine/threonine kinase 1 Homo sapiens 178-181 31669234-7 2020 In summary, these results indicated DLF induced ROS-mediated cell cycle arrest and apoptosis through ER stress and mitochondrial pathway accompanying with the inhibition of PI3K/AKT/mTOR and Ras/MEK/Erk signaling cascade. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 36-39 mechanistic target of rapamycin kinase Homo sapiens 182-186 31669234-7 2020 In summary, these results indicated DLF induced ROS-mediated cell cycle arrest and apoptosis through ER stress and mitochondrial pathway accompanying with the inhibition of PI3K/AKT/mTOR and Ras/MEK/Erk signaling cascade. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 36-39 mitogen-activated protein kinase kinase 7 Homo sapiens 195-198 31669234-7 2020 In summary, these results indicated DLF induced ROS-mediated cell cycle arrest and apoptosis through ER stress and mitochondrial pathway accompanying with the inhibition of PI3K/AKT/mTOR and Ras/MEK/Erk signaling cascade. 2-DEOXY-ALPHA-L-FUCOPYRANOSIDE 36-39 mitogen-activated protein kinase 1 Homo sapiens 199-202