PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
32211459-1	2020	The data have been obtained for a series of substituted pteridinones and pyrimidines that were developed based on BI-D1870 to establish a structure-activity relationship for RSK inhibition.	Pentasodium DTPA	117-122	ribosomal protein S6 kinase A3	Homo sapiens	174-177
21148481-4	2011	In rat ventricular myocytes, RSK activation by endothelin 1 (ET1) increased cMyBP-C phosphorylation at Ser(282), which was inhibited by the selective RSK inhibitor D1870.	Pentasodium DTPA	164-169	ribosomal protein S6 kinase polypeptide 1	Mus musculus	29-32
31344438-6	2019	D1870-mediated enhancement of PLN Ser16 phosphorylation was also observed after exposure to isoprenaline or noradrenaline (NA) stimuli that do not activate RSK.	Pentasodium DTPA	0-5	phospholamban	Rattus norvegicus	30-33
23593654-17	2013	Likewise, the RSK inhibitors, luteolin and BI-D1870, suppressed P-YB-1(S102) and thereby reduced Notch4.	Pentasodium DTPA	46-51	ribosomal protein S6 kinase A3	Homo sapiens	14-17
23593654-17	2013	Likewise, the RSK inhibitors, luteolin and BI-D1870, suppressed P-YB-1(S102) and thereby reduced Notch4.	Pentasodium DTPA	46-51	Y-box binding protein 1	Homo sapiens	66-70
23593654-17	2013	Likewise, the RSK inhibitors, luteolin and BI-D1870, suppressed P-YB-1(S102) and thereby reduced Notch4.	Pentasodium DTPA	46-51	notch receptor 4	Homo sapiens	97-103
21148481-4	2011	In rat ventricular myocytes, RSK activation by endothelin 1 (ET1) increased cMyBP-C phosphorylation at Ser(282), which was inhibited by the selective RSK inhibitor D1870.	Pentasodium DTPA	164-169	endothelin 1	Rattus norvegicus	47-59
21148481-4	2011	In rat ventricular myocytes, RSK activation by endothelin 1 (ET1) increased cMyBP-C phosphorylation at Ser(282), which was inhibited by the selective RSK inhibitor D1870.	Pentasodium DTPA	164-169	endothelin 1	Rattus norvegicus	61-64
21148481-4	2011	In rat ventricular myocytes, RSK activation by endothelin 1 (ET1) increased cMyBP-C phosphorylation at Ser(282), which was inhibited by the selective RSK inhibitor D1870.	Pentasodium DTPA	164-169	ribosomal protein S6 kinase polypeptide 1	Mus musculus	150-153