PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32368288-0 2020 HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment. UNII-QA3Y8EZG57 16-22 spermatogenesis associated 2 Homo sapiens 64-68 32368288-5 2020 In this study, we have shown that CG-745 induces microenvironment changes promoting anti-cancer effect of anti-PD-1 antibody in syngeneic mouse models. UNII-QA3Y8EZG57 34-40 programmed cell death 1 Mus musculus 111-115 32368288-6 2020 Specifically, CG-745 induces or extends IL-2 and IFN-gamma expression with or without additional stimulation, and increases proliferation of cytotoxic T cells and NK cells, while inhibiting proliferation of regulatory T cells. UNII-QA3Y8EZG57 14-20 interleukin 2 Homo sapiens 40-44 32368288-6 2020 Specifically, CG-745 induces or extends IL-2 and IFN-gamma expression with or without additional stimulation, and increases proliferation of cytotoxic T cells and NK cells, while inhibiting proliferation of regulatory T cells. UNII-QA3Y8EZG57 14-20 interferon gamma Homo sapiens 49-58