PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
27854076-4	2017	Additionally, DDI enhanced Akt phosphorylation, whereas phosphoinositide 3-kinase/Akt inhibitors suppressed DDI-induced glucose uptake.	didanosine	14-17	thymoma viral proto-oncogene 1	Mus musculus	27-30
28422741-4	2017	The CaM-interacting site of TBC1D3 was mapped to amino acids 157~171, which comprises two 1-14 hydrophobic motifs and one lysine residue (K166).	didanosine	138-142	calmodulin 1	Homo sapiens	4-7
28422741-4	2017	The CaM-interacting site of TBC1D3 was mapped to amino acids 157~171, which comprises two 1-14 hydrophobic motifs and one lysine residue (K166).	didanosine	138-142	TBC1 domain family member 3	Homo sapiens	28-34
27854076-4	2017	Additionally, DDI enhanced Akt phosphorylation, whereas phosphoinositide 3-kinase/Akt inhibitors suppressed DDI-induced glucose uptake.	didanosine	108-111	thymoma viral proto-oncogene 1	Mus musculus	82-85
34907844-2	2021	This study was aimed to compare DDI in emergency CS before and after the implementation of a specific care process improvement protocol, called "code blue".	didanosine	32-35	citrate synthase	Homo sapiens	49-51
23275890-10	2012	K204 of Ndc80 corresponds to K166 of human Ndc80 and the human Ndc80 K166E variant was previously shown to be defective for microtubule binding in vitro.	didanosine	29-33	NDC80 kinetochore complex component	Homo sapiens	8-13
23275890-10	2012	K204 of Ndc80 corresponds to K166 of human Ndc80 and the human Ndc80 K166E variant was previously shown to be defective for microtubule binding in vitro.	didanosine	29-33	NDC80 kinetochore complex component	Homo sapiens	43-48
23275890-10	2012	K204 of Ndc80 corresponds to K166 of human Ndc80 and the human Ndc80 K166E variant was previously shown to be defective for microtubule binding in vitro.	didanosine	29-33	NDC80 kinetochore complex component	Homo sapiens	43-48
9585526-11	1998	Analysis of the three-dimensional structure of Rac1 reveals that residues H103 and K166 are exposed on the surface of the molecule.	didanosine	83-87	Rac family small GTPase 1	Homo sapiens	47-51
24303140-5	2013	This DDI was completely abolished by intracellular infusion of the fast Ca(2+)-chelating agent BAPTA and by inhibition of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII).	didanosine	5-8	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	122-167
24303140-5	2013	This DDI was completely abolished by intracellular infusion of the fast Ca(2+)-chelating agent BAPTA and by inhibition of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII).	didanosine	5-8	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	169-175
19850744-6	2009	In the presence of ATRA, lysine 166 (K166) and K171 of RARA were modified at a physiological concentration of SUMO-2, whereas in the absence of ATRA, K399 was the only site that was modified, but at a higher SUMO-2 concentration.	didanosine	37-41	small ubiquitin-like modifier 2	Mus musculus	110-116
19202166-9	2009	Gating kinetics and sensitivity to XE991 indicated that DDI decreased cell-surface KCNQ1-MinK channels relative to homomeric KCNQ1, decreasing whole-cell current but increasing net activation rate; inhibiting DDI did the reverse.	didanosine	56-59	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	83-88
16758261-3	2006	A further therapeutic alternative is inhibition of catechol-O-methyltransfrase (COMT) on a regular basis, when levodopa/DDI treatment is performed.	didanosine	120-123	catechol-O-methyltransferase	Homo sapiens	51-78
16758261-3	2006	A further therapeutic alternative is inhibition of catechol-O-methyltransfrase (COMT) on a regular basis, when levodopa/DDI treatment is performed.	didanosine	120-123	catechol-O-methyltransferase	Homo sapiens	80-84
34907844-9	2021	The implementation of "code blue" protocol for emergency CS results in significantly shorter DDI and other time intervals.Impact StatementWhat is already known on this subject?	didanosine	93-96	citrate synthase	Homo sapiens	57-59
34907844-13	2021	The "code blue" protocol could be used as a model for other hospitals and health care settings to develop their own specific quality improvement process in order to shorten DDI for emergency CS.	didanosine	173-176	citrate synthase	Homo sapiens	191-193
34456745-6	2021	Mass spectrometry analyses identified lysine 166 (K166) in Rac1 as a residue targeted by SIRT1.	didanosine	50-54	Rac family small GTPase 1	Homo sapiens	59-63
34795154-6	2021	Furthermore, cell culture HCV revealed that the mutation with the K26 residue in combination with K139 or K166 on NS5A (2a, JFH1) resulted in complete abolishment of viral propagation, suggesting that the K26 residue collaborates with either the K139 residue or K166 residue for efficient HCV propagation.	didanosine	106-110	keratin 26	Homo sapiens	205-208
34795154-6	2021	Furthermore, cell culture HCV revealed that the mutation with the K26 residue in combination with K139 or K166 on NS5A (2a, JFH1) resulted in complete abolishment of viral propagation, suggesting that the K26 residue collaborates with either the K139 residue or K166 residue for efficient HCV propagation.	didanosine	262-266	keratin 26	Homo sapiens	66-69
34795154-6	2021	Furthermore, cell culture HCV revealed that the mutation with the K26 residue in combination with K139 or K166 on NS5A (2a, JFH1) resulted in complete abolishment of viral propagation, suggesting that the K26 residue collaborates with either the K139 residue or K166 residue for efficient HCV propagation.	didanosine	262-266	keratin 26	Homo sapiens	205-208
34456745-6	2021	Mass spectrometry analyses identified lysine 166 (K166) in Rac1 as a residue targeted by SIRT1.	didanosine	50-54	sirtuin 1	Homo sapiens	89-94
34456745-8	2021	Computational modeling analyses revealed that K166 deacetylation of Rac1 led to a 5-fold reduction in its binding affinity to guanosine-5"-triphosphate, and a 21-fold decrease in its binding potential to p67phox.	didanosine	46-50	Rac family small GTPase 1	Homo sapiens	68-72
34456745-8	2021	Computational modeling analyses revealed that K166 deacetylation of Rac1 led to a 5-fold reduction in its binding affinity to guanosine-5"-triphosphate, and a 21-fold decrease in its binding potential to p67phox.	didanosine	46-50	neutrophil cytosolic factor 2	Homo sapiens	204-211