PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32303640-7 2020 A multipronged systematic analysis of the reaction rates in the OADHc pathway, supplemented with results from chemical cross-linking and hydrogen-deuterium exchange MS, revealed that the c.2185G A DHTKD1 mutation affects E1a-E2o assembly, leading to impaired channeling of OADHc intermediates. 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine 225-228 dehydrogenase E1 and transketolase domain containing 1 Homo sapiens 197-203 22806154-9 2012 The recombinant E2o (rE2o) generated high IgG antibody and its isotypes IgG1, and induced significant production of INF-gamma, IL-10 and IL-4 cytokines. 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine 16-19 immunoglobulin heavy constant gamma 1 (G1m marker) Mus musculus 72-76 22806154-9 2012 The recombinant E2o (rE2o) generated high IgG antibody and its isotypes IgG1, and induced significant production of INF-gamma, IL-10 and IL-4 cytokines. 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine 16-19 interleukin 10 Mus musculus 127-132 22806154-9 2012 The recombinant E2o (rE2o) generated high IgG antibody and its isotypes IgG1, and induced significant production of INF-gamma, IL-10 and IL-4 cytokines. 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine 16-19 interleukin 4 Mus musculus 137-141