PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
12198133-6	2002	A cDNA (DOLPP1, GenBank accession number AB030189) from mouse brain encoding a homologue of the yeast CWH8 gene is now shown to complement the defects in growth and protein N-glycosylation, and to correct the accumulation of Dol-P-P in the cwh8Delta yeast mutant.	dolichol pyrophosphate	225-232	dolichyl pyrophosphate phosphatase 1	Mus musculus	8-14
21768116-1	2011	The oligosaccharyltransferase complex catalyzes the transfer of oligosaccharide from a dolichol pyrophosphate donor en bloc onto a free asparagine residue of a newly synthesized nascent chain during the translocation in the endoplasmic reticulum lumen.	dolichol pyrophosphate	87-109	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	4-29
16878994-4	2006	To address this issue, a biochemical approach was taken using recombinant Alg2 and Alg11 from S. cerevisiae and defined dolichylpyrophosphate-linked substrates.	dolichol pyrophosphate	120-141	GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	74-78
16177263-1	2006	CWH8/YGR036c of Saccharomyces cerevisiae has been identified as a dolichylpyrophosphate (Dol-PP) phosphatase that removes a phosphate from the Dol-PP generated by the oligosaccharyltransferase (OST), while it adds N-glycans to nascent glycoproteins in the endoplasmic reticulum (ER).	dolichol pyrophosphate	89-95	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	0-4
16177263-2	2006	Lack of CWH8 was proposed to interrupt the so called dolichol (Dol) cycle by trapping Dol in the form of Dol-PP in the ER lumen.	dolichol pyrophosphate	105-111	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	8-12
12198133-6	2002	A cDNA (DOLPP1, GenBank accession number AB030189) from mouse brain encoding a homologue of the yeast CWH8 gene is now shown to complement the defects in growth and protein N-glycosylation, and to correct the accumulation of Dol-P-P in the cwh8Delta yeast mutant.	dolichol pyrophosphate	225-232	dolichyl pyrophosphate phosphatase 1	Mus musculus	41-49
12198133-6	2002	A cDNA (DOLPP1, GenBank accession number AB030189) from mouse brain encoding a homologue of the yeast CWH8 gene is now shown to complement the defects in growth and protein N-glycosylation, and to correct the accumulation of Dol-P-P in the cwh8Delta yeast mutant.	dolichol pyrophosphate	225-232	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	102-106
12198133-13	2002	The specificity, subcellular location, and topological orientation of the active site described in the current study strongly support a role for Dolpp1p in the recycling of Dol-P-P discharged during protein N-glycosylation reactions on the luminal leaflet of the endoplasmic reticulum in mammalian cells.	dolichol pyrophosphate	173-180	dolichyldiphosphatase 1	Homo sapiens	145-152
10788335-1	2000	Glucosidase I is an important enzyme in N-linked glycoprotein processing, removing specifically distal alpha-1,2-linked glucose from the Glc3Man9GlcNAc2 precursor after its en bloc transfer from dolichyl diphosphate to a nascent polypeptide chain in the endoplasmic reticulum.	dolichol pyrophosphate	195-215	mannosyl-oligosaccharide glucosidase	Homo sapiens	0-13
11504728-2	2001	Genetic, enzymological, and topological approaches were taken to investigate the potential role of Cwh8p in Dol-P-P/Dol-P metabolism.	dolichol pyrophosphate	108-115	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	99-104
12217961-6	2002	In the patient"s fibroblasts, the biosynthetic intermediate GlcNAc(2)Man(7) oligosaccharide was detected both on the lipid carrier dolichyl pyrophosphate and on newly synthesized glycoproteins, thus pointing to a defect in the dolichyl pyrophosphate-GlcNAc(2)Man(7)-dependent ALG12 alpha1,6 mannosyltransferase.	dolichol pyrophosphate	131-153	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	276-281
32103179-6	2020	We used synthetic analogues of dolichylphosphate-linked and dolichylpyrophosphate-linked sugars and enzymatic glycan extension to generate donor and acceptor substrates using purified enzymes of the ALG pathway to recapitulate the activity of ALG6 in vitro.	dolichol pyrophosphate	60-81	dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase	Saccharomyces cerevisiae S288C	243-247
10966453-4	2000	They are formed by glucosidase I- and II-catalyzed partial deglucosylation of the oligosaccharide transferred from dolichol diphosphate derivatives to Asn residues in nascent polypeptide chains (Glc3Man9GlcNAc2).	dolichol pyrophosphate	115-135	mannosyl-oligosaccharide glucosidase	Homo sapiens	19-32
10359825-5	1999	Elaborating on the analogy of this finding with the phenotype of alg5 and alg6 Saccharomyces cerevisiae strains, we have cloned and analyzed the human orthologs to the ALG5 dolichyl phosphate glucosyltransferase and ALG6 dolichyl pyrophosphate Man9GlcNAc2 alpha1,3-glucosyltransferase in four novel CDGS patients.	dolichol pyrophosphate	221-243	ALG5 dolichyl-phosphate beta-glucosyltransferase	Homo sapiens	168-172
2182636-1	1990	The yeast gene ALG1 encodes a mannosyltransferase which participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation by catalyzing the formation of dolichol pyrophosphate (Dol-PP)-GlcNAc2Man from GDP-Man and Dol-PP-Glc-NAc2.	dolichol pyrophosphate	183-205	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	15-19
2182636-1	1990	The yeast gene ALG1 encodes a mannosyltransferase which participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation by catalyzing the formation of dolichol pyrophosphate (Dol-PP)-GlcNAc2Man from GDP-Man and Dol-PP-Glc-NAc2.	dolichol pyrophosphate	207-213	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	15-19
7018901-12	1981	The enzyme transfers besides dolichyl-diphosphate-bound (GlcNAc)2(Man)9(Glc)3 also (GlcNAc)2(Man)1 and (GlcNAc)2; the rate decreases in this order.	dolichol pyrophosphate	29-49	LEM domain containing 3	Homo sapiens	83-98
29301962-1	2018	Oligosaccharyltransferase (OST) is an essential membrane protein complex in the endoplasmic reticulum, where it transfers an oligosaccharide from a dolichol-pyrophosphate-activated donor to glycosylation sites of secretory proteins.	dolichol pyrophosphate	148-170	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	0-25
29301962-1	2018	Oligosaccharyltransferase (OST) is an essential membrane protein complex in the endoplasmic reticulum, where it transfers an oligosaccharide from a dolichol-pyrophosphate-activated donor to glycosylation sites of secretory proteins.	dolichol pyrophosphate	148-170	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
29301962-4	2018	The dolichol-pyrophosphate moiety binds to a lipid-exposed groove of STT3, whereas two noncatalytic subunits and an ordered N-glycan form a membrane-proximal pocket for the oligosaccharide.	dolichol pyrophosphate	4-26	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	69-73