PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
32293245-11	2020	Pretreatment with a GPR120 antagonist AH-7614, a GPR40 antagonist DC260126, or an ubiquitination inhibitor PYR-41 reduced the effect of DHA on cerulein-induced zymogen activation.	DC260126	66-74	free fatty acid receptor 1	Rattus norvegicus	49-54
32388601-4	2020	In the first part, the acute effects of EPA alone and in combination with GW1100 and DC260126 (FFAR1 blockers) on glucose homeostasis and hepatic phosphatidyl-inositol 4,5-bisphosphate (PIP2) and diacylglycerol (DAG) were investigated in standard chow diet (SCD)- and HFrHFD-fed mice.	DC260126	85-93	free fatty acid receptor 1	Mus musculus	95-100
23776696-0	2013	DC260126: a small-molecule antagonist of GPR40 that protects against pancreatic beta-Cells dysfunction in db/db mice.	DC260126	0-8	free fatty acid receptor 1	Mus musculus	41-46
31104992-4	2019	The ligand-protein interaction between this new molecule and the receptor was highlighted in the lower portion of the GPR40 groove that generally accommodates DC260126.	DC260126	159-167	free fatty acid receptor 1	Homo sapiens	118-123
31242961-5	2019	These effects were abolished by treatment with DC260126, a GPR40 antagonist, or GLP-2 (3-33), a GLP-2 antagonist.	DC260126	47-55	free fatty acid receptor 1	Mus musculus	59-64
31242961-7	2019	AS2034178 significantly increased the amount of GLP-2 in the colonic tissue, which was abolished by DC260126 but not GLP-2 (3-33).	DC260126	100-108	glucagon-like peptide 2 receptor	Mus musculus	48-53
23776696-3	2013	This study is designed to evaluate the potential effects of DC260126, a small molecule antagonist of GPR40, on beta-cell function following administration of 10 mg/kg dose of DC260126 to obese diabetic db/db mice.	DC260126	60-68	free fatty acid receptor 1	Mus musculus	101-106
23776696-7	2013	Moreover, DC260126 reduced the proinsulin/insulin ratio and the apoptotic rate of pancreatic beta-cells remarkably in DC260126-treated db/db mice compared to vehicle-treated mice (p<0.05, n = 8).	DC260126	10-18	insulin II	Mus musculus	31-41
22275065-3	2012	In this study, we investigated the possible effects of GPR40 in palmitate-induced MIN6 beta-cell apoptosis, and found that DC260126, a novel small molecular antagonist of GPR40, could protect MIN6 beta cells from palmitate-induced ER stress and apoptosis.	DC260126	123-131	free fatty acid receptor 1	Mus musculus	55-60
22275065-3	2012	In this study, we investigated the possible effects of GPR40 in palmitate-induced MIN6 beta-cell apoptosis, and found that DC260126, a novel small molecular antagonist of GPR40, could protect MIN6 beta cells from palmitate-induced ER stress and apoptosis.	DC260126	123-131	free fatty acid receptor 1	Mus musculus	171-176
20888730-3	2010	To this aim, we evaluated the effect of DC260126, a small-molecule antagonist of GPR40, on glucose and lipid metabolism in obese Zucker rats.	DC260126	40-48	free fatty acid receptor 1	Rattus norvegicus	81-86
20888730-0	2010	DC260126, a small-molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats.	DC260126	0-8	free fatty acid receptor 1	Rattus norvegicus	41-46