PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
33024080-8	2020	Furthermore, we detected the suppressed activity of CYP7B1 enzyme readily metabolizing the precursors of sex hormones on one hand but increased anti-glucocorticoid effect of 7alpha-hydroxy-DHEA via competition with cortisone for HSD11B1 on the other.	7alpha-Hydroxydehydroepiandrosterone	174-193	cytochrome P450 family 7 subfamily B member 1	Homo sapiens	52-58
33024080-8	2020	Furthermore, we detected the suppressed activity of CYP7B1 enzyme readily metabolizing the precursors of sex hormones on one hand but increased anti-glucocorticoid effect of 7alpha-hydroxy-DHEA via competition with cortisone for HSD11B1 on the other.	7alpha-Hydroxydehydroepiandrosterone	174-193	hydroxysteroid 11-beta dehydrogenase 1	Homo sapiens	229-236
33083728-2	2020	These neurosteroids are synthesized from cholesterol by a series of cytochrome P450 enzymes, among which a member of P450 hydroxylase, cytochrome P450-7b1 (CYP7B1), catalyzes the formation of 7alpha-hydroxylated neurosteroids, 7alpha-hydroxypregnenolone (7alpha-OH-Preg) and 7alpha-hydroxydehydroepiandrosterone (7alpha-OH-DHEA).	7alpha-Hydroxydehydroepiandrosterone	313-327	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	135-154
33083728-2	2020	These neurosteroids are synthesized from cholesterol by a series of cytochrome P450 enzymes, among which a member of P450 hydroxylase, cytochrome P450-7b1 (CYP7B1), catalyzes the formation of 7alpha-hydroxylated neurosteroids, 7alpha-hydroxypregnenolone (7alpha-OH-Preg) and 7alpha-hydroxydehydroepiandrosterone (7alpha-OH-DHEA).	7alpha-Hydroxydehydroepiandrosterone	313-327	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	156-162
33083728-6	2020	Furthermore, chronic intracerebroventricular administration of a mixture of 7alpha-OH-Preg and 7alpha-OH-DHEA rescued the deteriorated remote memory performance in Cyp7b1-deficient mice.	7alpha-Hydroxydehydroepiandrosterone	95-109	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	164-170
16855167-3	2006	The described immuno-stimulating effects of DHEA may be due to the conversion of DHEA into 7alpha-hydroxy-DHEA (7alpha-OH-DHEA) by the activity of the p450 enzyme, Cyp7b.	7alpha-Hydroxydehydroepiandrosterone	112-126	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	151-155
15476247-11	2004	Incubation of FLS with IL-1beta resulted in a dose-dependent increase in 7alpha-OH-DHEA formation.	7alpha-Hydroxydehydroepiandrosterone	73-87	interleukin 1 beta	Mus musculus	23-31