PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
35268019-3	2022	We previously demonstrated that Korean red ginseng extract (RGE) decreases H. pylori-induced increases in ROS and monocyte chemoattractant protein 1 in gastric epithelial cells.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	60-63	C-C motif chemokine ligand 2	Homo sapiens	114-148
34575573-7	2021	The amoxicillin pretreatment (20 mg/kg/day, twice a day for 3 days) resulted in a significant decrease in the fecal recovery of CK, PPD, and PPT through the blockade of deglycosylation of ginsenosides after single oral administrations of RGE (2 g/kg) in mice.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	238-241	palmitoyl-protein thioesterase 1	Mus musculus	141-144
34575573-11	2021	Therefore, the supplementation of LAB with oral administrations of RGE would help increase plasma concentrations of deglycosylated ginsenosides such as CK, PPD, and PPT.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	67-70	palmitoyl-protein thioesterase 1	Mus musculus	165-168
34371714-4	2021	RGE-SiO2 formulation increased intestinal permeability of ginsenoside Rb1 (GRb1), GRb2, GRc, and GRd by 1.6-fold in rat jejunal segments as measured by the Ussing chamber system.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	0-3	RB transcriptional corepressor 1	Rattus norvegicus	70-73
34371714-4	2021	RGE-SiO2 formulation increased intestinal permeability of ginsenoside Rb1 (GRb1), GRb2, GRc, and GRd by 1.6-fold in rat jejunal segments as measured by the Ussing chamber system.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	0-3	growth factor receptor bound protein 2	Rattus norvegicus	82-86
34371714-5	2021	A 1.6- to 1.8-fold increase in plasma exposure of GRb1, GRb2, GRc, and GRd in rats was observed following oral administration of RGE-SiO2 (375 mg/kg as RGE).	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	129-132	growth factor receptor bound protein 2	Rattus norvegicus	56-60
35268019-4	2022	We determined whether RGE suppresses the expression of IL-8 via Nrf2 activation and the expression of SOD and HO-1 in H. pylori-infected gastric epithelial AGS cells.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	22-25	C-X-C motif chemokine ligand 8	Homo sapiens	55-59
35268019-4	2022	We determined whether RGE suppresses the expression of IL-8 via Nrf2 activation and the expression of SOD and HO-1 in H. pylori-infected gastric epithelial AGS cells.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	22-25	NFE2 like bZIP transcription factor 2	Homo sapiens	64-68
35268019-4	2022	We determined whether RGE suppresses the expression of IL-8 via Nrf2 activation and the expression of SOD and HO-1 in H. pylori-infected gastric epithelial AGS cells.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	22-25	superoxide dismutase 1	Homo sapiens	102-105
35268019-4	2022	We determined whether RGE suppresses the expression of IL-8 via Nrf2 activation and the expression of SOD and HO-1 in H. pylori-infected gastric epithelial AGS cells.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	22-25	heme oxygenase 1	Homo sapiens	110-114
35268019-5	2022	H. pylori-infected cells were treated with RGE with or without ML385, an Nrf2 inhibitor, or zinc protoporphyrin (ZnPP), a HO-1 inhibitor.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	43-46	NFE2 like bZIP transcription factor 2	Homo sapiens	73-77
35268019-8	2022	H. pylori infection decreased the protein levels of SOD-1 and HO-1, as well as SOD activity, which was reversed by RGE treatment.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	115-118	superoxide dismutase 1	Homo sapiens	52-57
35268019-8	2022	H. pylori infection decreased the protein levels of SOD-1 and HO-1, as well as SOD activity, which was reversed by RGE treatment.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	115-118	heme oxygenase 1	Homo sapiens	62-66
35268019-8	2022	H. pylori infection decreased the protein levels of SOD-1 and HO-1, as well as SOD activity, which was reversed by RGE treatment.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	115-118	superoxide dismutase 1	Homo sapiens	79-82
33642802-11	2021	Furthermore, treatment with RGE resulted in a 10.80% decrease in the level of ACE.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	28-31	angiotensin I converting enzyme	Rattus norvegicus	78-81
33192124-3	2020	In this study, we investigated the effect of non-saponin components of RGE on AIM2 inflammasome activation.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	71-74	absent in melanoma 2	Mus musculus	78-82
31234321-8	2019	In vitro and in vivo findings indicated that RGE significantly improves Abeta-induced mitochondrial pathology.	(2s)-2-Amino-5-(2-(Methylsulfinyl)acetimidamido)pentanoic Acid	45-48	amyloid beta (A4) precursor protein	Mus musculus	72-77