PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
16928193-4	2007	Compared with the wild-type form, elimination of three out of the four cysteine residues decreased the catalytic efficiency of PPI (peptidyl-prolyl cis-trans isomerase) activity of the reduced CYP20-3, indicating a regulatory role of dithiol-disulfide transitions in protein function.	dithiol-disulfide	234-251	peptidyl-prolyl cis-trans isomerase	Arabidopsis thaliana	132-167
8430514-5	1993	The dithiol-disulfide loop represented by this structure is unique since the cystine closer to the N-terminus has a highly acidic thiol pKa (3.8 as determined for the pig liver enzyme) that contributes to the protein"s high S- nucleophilicity.	dithiol-disulfide	4-21	protein kinase cAMP-activated catalytic subunit alpha	Sus scrofa	136-139
24133216-0	2013	Identification of a dithiol-disulfide switch in collapsin response mediator protein 2 (CRMP2) that is toggled in a model of neuronal differentiation.	dithiol-disulfide	20-37	dihydropyrimidinase like 2	Homo sapiens	48-85
24133216-0	2013	Identification of a dithiol-disulfide switch in collapsin response mediator protein 2 (CRMP2) that is toggled in a model of neuronal differentiation.	dithiol-disulfide	20-37	dihydropyrimidinase like 2	Homo sapiens	87-92
24133216-4	2013	In this study, we demonstrate the molecular mechanism of this regulation, a specific and reversible intermolecular Cys-504-Cys-504 dithiol-disulfide switch in homotetrameric CRMP2.	dithiol-disulfide	131-148	dihydropyrimidinase like 2	Homo sapiens	174-179
23872354-0	2013	Identification of potential protein dithiol-disulfide substrates of mammalian Grx2.	dithiol-disulfide	36-53	glutaredoxin 2	Homo sapiens	78-82
33065363-3	2021	Thioredoxin (Trx) is a 12-kDa endogenous protein that exerts antioxidant activity by promoting dithiol disulfide exchange reactions.	dithiol-disulfide	95-112	thioredoxin 1	Mus musculus	0-11
33065363-3	2021	Thioredoxin (Trx) is a 12-kDa endogenous protein that exerts antioxidant activity by promoting dithiol disulfide exchange reactions.	dithiol-disulfide	95-112	thioredoxin 1	Mus musculus	13-16
23350160-1	2010	Thioredoxin (TRX) proteins perform important biological functions in cells by changing the redox state of proteins via dithiol disulfide exchange.	dithiol-disulfide	119-136	thioredoxin	Homo sapiens	0-11
23350160-1	2010	Thioredoxin (TRX) proteins perform important biological functions in cells by changing the redox state of proteins via dithiol disulfide exchange.	dithiol-disulfide	119-136	thioredoxin	Homo sapiens	13-16