PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
15012146-7	2004	This is supported by DFT calculations (B3LYP/6-31G(d)), which predicted the rotational barriers in the dications of unsubstituted bithiophene and terthiophene to be 27.6 and 22.9 kcal mol(-)(1), respectively.	2,2'-Bithiophene	130-141	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	41-44
12353985-6	2002	This is the first instance where a bithiophene has been shown to adopt a conformation where the sulfur atoms are completely syn.	2,2'-Bithiophene	35-46	synemin	Homo sapiens	124-127
33191503-2	2021	In this work, the synthesis of a novel bithiophene-bridged donor-acceptor-based 2D sp2 -carbon-linked conjugated polymer (2D CCP) is demonstrated.	2,2'-Bithiophene	39-50	Sp2 transcription factor	Homo sapiens	83-86
34837464-2	2022	Herein, the authors develop a series of simple non-fused-ring electron donors, PF1 and PF2, which alternately consist of furan-3-carboxylate and 2,2"-bithiophene.	2,2'-Bithiophene	145-161	PHD finger protein 12	Homo sapiens	79-82
35431190-0	2022	Bithiophene derivative induced apoptosis and suppression of Akt pathway in mouse leukemic model.	2,2'-Bithiophene	0-11	thymoma viral proto-oncogene 1	Mus musculus	60-63
11777461-5	2002	Again, comparison with the parent compounds based on an unsubstituted bithiophene spacer reveals a marked red shift of the absorption maximum and a large enhancement of mu beta.	2,2'-Bithiophene	70-81	ubiquitin like 3	Homo sapiens	169-176
34850563-5	2022	Detailed mechanism studies reveal that the optimized photosensitizer, WS2D, which contains a bithiophene unit, could both promote charge carrier generation and accelerate reaction efficiency, resulting in the efficient production of  OH.	2,2'-Bithiophene	93-104	snail family transcriptional repressor 2	Homo sapiens	70-74
35099929-2	2022	The FlexLP ligand encompasses a diphenylphosphine oxide Lewis base and a dimesitylborane Lewis acid attached to a bithiophene scaffold, which can switch between an open unbound Lewis pair and a bound P-O-B Lewis adduct depending on the hydrogen bond-donating (HBD) strength of the solvent.	2,2'-Bithiophene	114-125	ER membrane protein complex subunit 3	Homo sapiens	200-205
27459633-1	2016	For rapid screening and quantification of an antisera antibody, a nanometer bithiophene-based conductive biolinker can enhanced signal performance and can be used to verify the interaction of an anti-IFN-gamma antibody with an IFN-gamma protein.	2,2'-Bithiophene	76-87	interferon gamma	Homo sapiens	200-209
31183039-0	2019	Synthesis of a one-handed helical polythiophene: a new approach using an axially chiral bithiophene with a fixed syn-conformation.	2,2'-Bithiophene	88-99	synemin	Homo sapiens	113-116
31183039-5	2019	Partial conformational regulation derived from the fixed syn-conformation of the chiral bithiophene unit was considered a key factor in producing the one-handed helical polythiophene.	2,2'-Bithiophene	88-99	synemin	Homo sapiens	57-60
30043030-5	2018	We also unveil a relevant dependence of Deltamuge with the odd-even parity of n and that Deltamuge assumes higher values when the molecule is composed by bithiophene (instead of simple thiophenes) moieties in the syn-conformation (with the two heteroatoms pointing in the same direction).	2,2'-Bithiophene	154-165	synemin	Homo sapiens	213-216
29722089-1	2018	Two novel, donor-acceptor-type pi-conjugated polymers (P1 and P2) with 3"-(thieno[3,2-b]thiophene-2,5-diylbis(methan-1-yl-1-ylidene))bis-(indolin-2-one) (ITTI) as the acceptor and thiophene/bithiophene as the donor are designed and synthesized by palladium-catalyzed Stille coupling.	2,2'-Bithiophene	190-201	crystallin gamma F, pseudogene	Homo sapiens	55-64
28257025-2	2017	A previously reported C-shaped molecule with bithiophene-substituted quinoxaline rings suspended from an aliphatic bridge that holds the aromatic rings in close proximity exists as a pair of syn and anti diastereomers.	2,2'-Bithiophene	45-56	synemin	Homo sapiens	191-194
27459633-1	2016	For rapid screening and quantification of an antisera antibody, a nanometer bithiophene-based conductive biolinker can enhanced signal performance and can be used to verify the interaction of an anti-IFN-gamma antibody with an IFN-gamma protein.	2,2'-Bithiophene	76-87	interferon gamma	Homo sapiens	227-236
27459633-5	2016	We compared the response and concentration of the anti-IFN-gamma antibody on a bithiophene-coated and dextran-coated biochip as well as on different thickness-modified surfaces under SPR relevant conditions.	2,2'-Bithiophene	79-90	interferon gamma	Homo sapiens	55-64
27459633-6	2016	The results indicate that a response to IFN-gamma molecules immobilized on a sensor using a bithiophene biolinker improved more than 8-fold when compared to that of a sensor using a dextran biolinker.	2,2'-Bithiophene	92-103	interferon gamma	Homo sapiens	40-49
27097642-2	2016	In this work, we incorporated rigid 2,2"-bithiophene (BT) or fluorinated 2,2"-bithiophene (FBT) as the central unit and synthesized two novel small molecules (TTH-D3TRh and TTF-D3TRh) with an oligothiophene backbone and 3-ethylrhodanine end groups.	2,2'-Bithiophene	36-52	ras homolog family member H	Homo sapiens	173-176
27097642-2	2016	In this work, we incorporated rigid 2,2"-bithiophene (BT) or fluorinated 2,2"-bithiophene (FBT) as the central unit and synthesized two novel small molecules (TTH-D3TRh and TTF-D3TRh) with an oligothiophene backbone and 3-ethylrhodanine end groups.	2,2'-Bithiophene	73-89	ras homolog family member H	Homo sapiens	173-176
23939290-2	2013	PyDPP was polymerized with bithiophene (BT) to afford a low band-gap copolymer (PBTPyDPP) which was used as an electron donor of the active layer in polymer solar cells.	2,2'-Bithiophene	27-38	dentin sialophosphoprotein	Homo sapiens	80-88
26645584-1	2015	New regular and random diketopyrrolopyrrole (DPP)-based terpolymers (i.e., Reg-PBDPPT and Ran-PBDPPT, respectively) bearing DPP as an electron deficient unit and 2,2"-bithiophene and (E)-1,2-di(thiophen-2-yl)ethene as electron donating units were designed and synthesized, and their performance in photovoltaic cells was investigated precisely.	2,2'-Bithiophene	162-178	regenerating family member 1 alpha	Homo sapiens	75-78
21994140-5	2012	Hex-T3 TM not only appeared in the crystalline state but also the amorphous state, which was stable to up to 80  C. Regardless of the terminal groups, the derivatives of n=2 exhibited a broad fluorescence with large Stokes shifts compared to the corresponding linear analogues, thereby suggesting the presence of intramolecular interactions between the bithiophene moieties.	2,2'-Bithiophene	353-364	hematopoietically expressed homeobox	Homo sapiens	0-3
22671580-1	2012	A new N-heterocyclic carbene (NHC) containing a fused bithiophene backbone has been synthesized along with its silver(I) and BPh(3) complexes.	2,2'-Bithiophene	54-65	high mobility group nucleosomal binding domain 4	Homo sapiens	6-34
19526470-2	2009	These molecules are designed as electrochemically polymerizable monomers that will yield the highly cross-linked conducting polymeric networks poly[Por(BT)(4)] and poly[PorZn(BT)(4)], respectively, through an oxidative coupling reaction among the bithiophene moieties.	2,2'-Bithiophene	247-258	cytochrome p450 oxidoreductase	Homo sapiens	148-151
20938932-0	2010	Synthesis and properties of terthiophene and bithiophene derivatives functionalized by BF2 chelation: a new type of electron acceptor based on quadrupolar structures.	2,2'-Bithiophene	45-56	forkhead box G1	Homo sapiens	87-90
19526470-1	2009	Dye-functionalized conducting polymers: A new concept in the design of monomers gives bithiophene-based monomers as "isolated" functional dyes, thus yielding electroactive films through anodic electrochemical polymerization (see picture).We have synthesized doubly strapped porphyrin derivatives with four bithiophene segments that diverge from the porphyrin core, namely, Por(BT)(4) and PorZn(BT)(4).	2,2'-Bithiophene	86-97	cytochrome p450 oxidoreductase	Homo sapiens	373-376