PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21296658-0	2011	Differential accumulation of HCBz and PeCBz in porcine ovarian follicles and their opposing actions on steroid secretion and CYP11, CYP17, 17beta-HSD and CYP19 protein expression.	pentachlorobenzene	38-43	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	132-137
21296658-0	2011	Differential accumulation of HCBz and PeCBz in porcine ovarian follicles and their opposing actions on steroid secretion and CYP11, CYP17, 17beta-HSD and CYP19 protein expression.	pentachlorobenzene	38-43	hydroxysteroid 17-beta dehydrogenase 1	Homo sapiens	139-149
21296658-0	2011	Differential accumulation of HCBz and PeCBz in porcine ovarian follicles and their opposing actions on steroid secretion and CYP11, CYP17, 17beta-HSD and CYP19 protein expression.	pentachlorobenzene	38-43	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	154-159
20131084-7	2010	A low degree of nitro group removal resulting in the formation of pentachlorobenzene (PeCB) was also observed in the control culture when amended with 13 muM PCNB.	pentachlorobenzene	66-84	latexin	Homo sapiens	154-157
20131084-7	2010	A low degree of nitro group removal resulting in the formation of pentachlorobenzene (PeCB) was also observed in the control culture when amended with 13 muM PCNB.	pentachlorobenzene	86-90	latexin	Homo sapiens	154-157
15515957-4	2004	Finally, the AhR acitivity of hexachlorobenzene and pentachlorobenzene were assessed, and their toxicity equivalent factors were found to be 0.018629 and 0.000294, respectively.	pentachlorobenzene	52-70	aryl hydrocarbon receptor	Homo sapiens	13-16
9630449-1	1998	A distinct, nonfocal expression pattern was observed for glutathione S-transferase P1-1 (rGSTP1-1) in rats exposed to either hexachloro-(HCB) or pentachlorobenzene (PeCB).	pentachlorobenzene	145-163	glutathione S-transferase pi 1	Rattus norvegicus	89-97
12700395-1	2003	A combination of experimental and simulation approaches was used to analyze clonal growth of glutathione-S-transferase pi (GST-P) enzyme-altered foci during liver carcinogenesis in an initiation-promotion regimen for 1,4-dichlorobenzene (DCB), 1,2,4,5-tetrachlorobenzene (TECB), pentachlorobenzene (PECB), and hexachlorobenzene (HCB).	pentachlorobenzene	279-297	glutathione S-transferase pi 1	Rattus norvegicus	123-128
12700395-1	2003	A combination of experimental and simulation approaches was used to analyze clonal growth of glutathione-S-transferase pi (GST-P) enzyme-altered foci during liver carcinogenesis in an initiation-promotion regimen for 1,4-dichlorobenzene (DCB), 1,2,4,5-tetrachlorobenzene (TECB), pentachlorobenzene (PECB), and hexachlorobenzene (HCB).	pentachlorobenzene	299-303	glutathione S-transferase pi 1	Rattus norvegicus	123-128
9630449-1	1998	A distinct, nonfocal expression pattern was observed for glutathione S-transferase P1-1 (rGSTP1-1) in rats exposed to either hexachloro-(HCB) or pentachlorobenzene (PeCB).	pentachlorobenzene	165-169	glutathione S-transferase pi 1	Rattus norvegicus	89-97
9630449-3	1998	A Western blot analysis revealed a 5- and 15-fold induction of rGSTP1-1 with PeCB and HCB treatment on an equal molar basis, respectively.	pentachlorobenzene	77-81	glutathione S-transferase pi 1	Rattus norvegicus	63-69
7747284-5	1995	The ratio between the activities of CYP2E1 and CYP3A4 with respect to the oxidation of chlorinated benzenes decreased from 150 (1,2-dichlorobenzene) to 1.8 (pentachlorobenzene).	pentachlorobenzene	157-175	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	36-42
7747284-5	1995	The ratio between the activities of CYP2E1 and CYP3A4 with respect to the oxidation of chlorinated benzenes decreased from 150 (1,2-dichlorobenzene) to 1.8 (pentachlorobenzene).	pentachlorobenzene	157-175	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	47-53
7747284-3	1995	Furthermore, CYP1A1 and CYP1A2 showed relatively high enzymatic activities toward the lower chlorinated benzenes (1,2-dichlorobenzene, 1,4-dichlorobenzene, 1,2,4-trichlorobenzene) and CYP3A4 toward the higher chlorinated benzenes (1,2,3,5-tetrachlorobenzene, pentachlorobenzene).	pentachlorobenzene	259-277	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	13-19
12209162-0	1991	NTP technical report on the toxicity studies of Pentachlorobenzene in F344/N Rats and B6C3F1 Mice (Feed Studies) (CAS No.	pentachlorobenzene	48-66	breast cancer anti-estrogen resistance 1	Mus musculus	114-117
7747284-3	1995	Furthermore, CYP1A1 and CYP1A2 showed relatively high enzymatic activities toward the lower chlorinated benzenes (1,2-dichlorobenzene, 1,4-dichlorobenzene, 1,2,4-trichlorobenzene) and CYP3A4 toward the higher chlorinated benzenes (1,2,3,5-tetrachlorobenzene, pentachlorobenzene).	pentachlorobenzene	259-277	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	24-30
8156603-5	1994	The biotransformation of HCB and PCBz was modulated by selective inhibition of cytochrome P450IIIA in rats which received combined treatment of HCB or PCBz with triacetyloleandomycin (TAO).	pentachlorobenzene	33-37	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	90-98
8156603-5	1994	The biotransformation of HCB and PCBz was modulated by selective inhibition of cytochrome P450IIIA in rats which received combined treatment of HCB or PCBz with triacetyloleandomycin (TAO).	pentachlorobenzene	151-155	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	90-98
23852585-5	2014	Among the phthalocyanine-type pigments, highly chlorinated PCBs, mainly composed of PCB-209, PeCBz, and HxCBz were detected.	pentachlorobenzene	93-98	pyruvate carboxylase	Homo sapiens	59-62
3768314-6	1986	Pentachlorobenzene (PCB) appears to be the initial and major isolatable CYT P-450 mediated dechlorination product of HCB with NADPH-fortified rat liver microsomes.	pentachlorobenzene	0-18	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	72-81
3768314-6	1986	Pentachlorobenzene (PCB) appears to be the initial and major isolatable CYT P-450 mediated dechlorination product of HCB with NADPH-fortified rat liver microsomes.	pentachlorobenzene	20-23	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	72-81
3768314-10	1986	The data indicate that CYT P-450 in hepatic microsomes supports the reductive dechlorination of HCB to PCB.	pentachlorobenzene	103-106	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	23-32
3596752-0	1986	Hexachlorobenzene and substituted pentachlorobenzenes (X-C6Cl5) as inducers of hepatic cytochrome P-450-dependent mono-oxygenases.	pentachlorobenzene	34-53	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	87-103
3596752-2	1986	Levels of individual cytochrome P-450 isozymes and various mono-oxygenase activities in liver microsomes from rats treated with substituted pentachlorobenzene (X-C6Cl5) and 4"-substituted-2,3,4,5-tetrachlorobiphenyl (X-C12 H5Cl4) analogues demonstrated the remarkable effects of substituent structure on induction activities.	pentachlorobenzene	140-158	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	21-37
2675838-4	1989	During this cytochrome P450-dependent conversion of pentachlorobenzene, 5-15% of the total amount of metabolites becomes covalently bound to microsomal protein.	pentachlorobenzene	52-70	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	12-27
25892359-6	2015	Liver CYP1A1 expression correlated positively and significantly with blubber concentrations of all POP categories (n = 39, p < 0.050) except octachlorostyrene and pentachlorobenzene (p > 0.100).	pentachlorobenzene	166-184	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	6-12