PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 11746366-3 2001 L-Aspartate, L-glutamate and L-cysteate produced an equivalent degree of [3H] exchange to that observed with D-aspartate, although the non-substrate EAAT2 inhibitor dihydrokainate and D-glutamate, which does not interact with the substrate binding site, failed to stimulate [3H]D-aspartate exchange. L-Cysteic acid 29-39 solute carrier family 1 member 2 Homo sapiens 149-154 12649361-3 2003 We discovered that L-homocysteine sulfinic acid (L-HCSA), L-homocysteic acid, L-cysteine sulfinic acid, and L-cysteic acid are potent and effective agonists at several rat metabotropic glutamate receptors (mGluRs). L-Cysteic acid 108-122 glutamyl-tRNA synthetase 2, mitochondrial Mus musculus 206-212 19923702-4 2009 CAM contains bi-layers of L-cysteic acid molecules separated by water molecules which form donor interactions to the bi-layers above and below. L-Cysteic acid 26-40 calmodulin 3 Homo sapiens 0-3 34068845-6 2021 We determined the kinetic constants using L-cysteine sulfinic acid as substrate, and also showed that human cysteine sulfinic acid decarboxylase is capable to catalyze the decarboxylation-besides its natural substrates L-cysteine sulfinic acid and L-cysteic acid-of L-aspartate and L-glutamate, although with much lower efficiency. L-Cysteic acid 248-262 cysteine sulfinic acid decarboxylase Homo sapiens 108-144 34664263-27 2021 The pooled results for the exploratory outcome, the rate of exacerbations requiring oral corticosteroids (OCS) or hospitalisation or emergency department visit, may be lower in participants receiving anti-interleukin-13/-4 agents versus placebo (rate ratio 0.71, 95% CI 0.65 to 0.77; low-certainty evidence). L-Cysteic acid 106-109 interleukin 13 Homo sapiens 205-219 34959433-4 2021 The mucin adsorption of Cur-NSs was steeply increased about 3-4 times by CS and OCS coating. L-Cysteic acid 80-83 LOC100508689 Homo sapiens 4-9 35487369-1 2022 BACKGROUND: Reslizumab, a biologic targeting interleukin-5 has been shown to reduce asthma exacerbations and maintenance oral corticosteroid (OCS) use in randomized controlled trials and pre-post studies in patients with severe eosinophilic asthma. L-Cysteic acid 142-145 interleukin 5 Homo sapiens 45-58 35618669-10 2022 Therefore, OCS is a safe and effective technique to enlarge the cardiac donor pool in both DBD and DCD, with additional benefits for long-distance transport and surgically complex procedures. L-Cysteic acid 11-14 dermcidin Homo sapiens 99-102 35574049-4 2023 In this study, a regenerative scaffold regulating the macrophage immune microenvironment and promoting bone regeneration in a dual-stage process for the postoperative treatment of bone tumors was constructed by binding a colony-stimulating factor 1 receptor (CSF-1R) inhibitor GW2580 onto in situ cosslinked hydroxybutylchitosan (HBC)/oxidized chondroitin sulfate (OCS) hydrogel layer covering a 3D printed calcium phosphate scaffold based on electrostatic interaction. L-Cysteic acid 365-368 colony stimulating factor 1 receptor Homo sapiens 221-257 35574049-4 2023 In this study, a regenerative scaffold regulating the macrophage immune microenvironment and promoting bone regeneration in a dual-stage process for the postoperative treatment of bone tumors was constructed by binding a colony-stimulating factor 1 receptor (CSF-1R) inhibitor GW2580 onto in situ cosslinked hydroxybutylchitosan (HBC)/oxidized chondroitin sulfate (OCS) hydrogel layer covering a 3D printed calcium phosphate scaffold based on electrostatic interaction. L-Cysteic acid 365-368 colony stimulating factor 1 receptor Homo sapiens 259-265 33314542-10 2021 CONCLUSIONS: We established patient need for a decision aid on OCS use during pregnancy that providers can discuss with patients. L-Cysteic acid 63-66 activation induced cytidine deaminase Homo sapiens 56-59 6955797-3 1982 Intensification of CSADCase immunoreactivity was achieved by pretreatment of the animal with L-cysteine or L-cysteic acid intravenously 1-2 hr prior to perfusion. L-Cysteic acid 107-121 cysteine sulfinic acid decarboxylase Rattus norvegicus 19-27 6955797-4 1982 A combination of L-cysteic acid and demecolcine, which retards axoplasmic flow, was most effective in maximizing CSADCase immunoreactivity. L-Cysteic acid 17-31 cysteine sulfinic acid decarboxylase Rattus norvegicus 113-121 35288647-8 2022 Notably, only the U-ATX levels inversely fluctuated depending on the status of disease activity whether OCS had been used or not. L-Cysteic acid 104-107 ectonucleotide pyrophosphatase/phosphodiesterase 2 Homo sapiens 20-23 33221959-10 2021 The increase in IL-6 level induced by OCS was maintained for 24 h. The OCS also increased the number of white blood cells and the percentage of neutrophils in BALFs. L-Cysteic acid 38-41 interleukin 6 Mus musculus 16-20 33413387-6 2021 In multivariate analyses, sputum ACE2 levels were positively associated with OCS use and male gender. L-Cysteic acid 77-80 angiotensin converting enzyme 2 Homo sapiens 33-37 33421388-7 2021 Median operation time during HTx in the OCS group was 616 (270- 809) min vs. 329 (283- 617) min. L-Cysteic acid 40-43 Zic family member 3 Homo sapiens 29-32 32937821-7 2020 In addition to direct impact on OCs and OBs, the activity of NRF2 on myeloma cells and mesenchymal stromal cells influences the inflammatory stress/ROS level in these cells, which has an impact on OCs, OBs, and osteocytes. L-Cysteic acid 32-35 NFE2 like bZIP transcription factor 2 Homo sapiens 61-65 31933103-9 2020 We also compared the effects of several OCs that are oxidized at the carbon-6 and -7 in the B-ring of cholesterol on FASN gene promoter activities. L-Cysteic acid 40-43 fatty acid synthase Homo sapiens 117-121 30940770-2 2019 High-dose OCS reduced median blood eosinophils (-60 cells/microl; 95% CI -140 to 10), periostin (-8.4 ng/mL; -11.6 to -2.8), FeNO (-19.0 ppb; -28.5 to -4.0), IL-5 (-0.17 pg/mL; -0.28 to -0.08) and IL-13 (-0.15 pg/mL; -0.27 to -0.03). L-Cysteic acid 10-13 periostin Homo sapiens 86-95 30940770-2 2019 High-dose OCS reduced median blood eosinophils (-60 cells/microl; 95% CI -140 to 10), periostin (-8.4 ng/mL; -11.6 to -2.8), FeNO (-19.0 ppb; -28.5 to -4.0), IL-5 (-0.17 pg/mL; -0.28 to -0.08) and IL-13 (-0.15 pg/mL; -0.27 to -0.03). L-Cysteic acid 10-13 interleukin 5 Homo sapiens 158-162 30940770-2 2019 High-dose OCS reduced median blood eosinophils (-60 cells/microl; 95% CI -140 to 10), periostin (-8.4 ng/mL; -11.6 to -2.8), FeNO (-19.0 ppb; -28.5 to -4.0), IL-5 (-0.17 pg/mL; -0.28 to -0.08) and IL-13 (-0.15 pg/mL; -0.27 to -0.03). L-Cysteic acid 10-13 interleukin 13 Homo sapiens 197-202 29849682-4 2017 The level of serum IL-8 was compared between the glucocorticosteroid groups, receiving inhaled corticosteroids (ICs), oral corticosteroids (OCs), and intravenous corticosteroids (GCs), respectively. L-Cysteic acid 140-143 C-X-C motif chemokine ligand 8 Homo sapiens 19-23 24754754-2 2014 The water-mediated neutral hydrolysis mechanism of carbonyl sulfide (OCS) has been re-examined using the hybrid supramolecule/continuum models with n = 2-8 explicit water cluster at the level of MP2(fc)(CPCM)/6-311++G(d,p)//MP2(fc)(CPCM)/6-31+G(d). L-Cysteic acid 69-72 tryptase pseudogene 1 Homo sapiens 195-198 24754754-2 2014 The water-mediated neutral hydrolysis mechanism of carbonyl sulfide (OCS) has been re-examined using the hybrid supramolecule/continuum models with n = 2-8 explicit water cluster at the level of MP2(fc)(CPCM)/6-311++G(d,p)//MP2(fc)(CPCM)/6-31+G(d). L-Cysteic acid 69-72 tryptase pseudogene 1 Homo sapiens 224-227 31603626-3 2019 In our study, astilbin was found to have an inhibitory effect on the RANKL-induced formation and function of OCs in a dose-dependent manner without cytotoxicity. L-Cysteic acid 109-112 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 69-74