PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
20233198-4	2010	RESULTS: Prior administration of terbutaline led to a 44% increase in absorption of insulin over 6 h for the Rev+ group compared with no prior administration of bronchodilator [ratio (95% confidence interval) 1.44 (1.13, 1.82), P= 0.004], whereas no effect was seen for the Rev- or the whole group.	REV	109-112	insulin	Homo sapiens	84-91
25486595-1	2014	The HIV Rev protein routes viral RNAs containing the Rev Response Element (RRE) through the Crm1 nuclear export pathway to the cytoplasm where viral proteins are expressed and genomic RNA is delivered to assembling virions.	REV	8-11	exportin 1	Homo sapiens	92-96
26075509-2	2015	After translation, Rev enters the nucleus and binds the Rev response element (RRE), a ~350 nucleotide, highly structured element embedded in the env gene in unspliced and singly spliced viral RNA transcripts.	REV	19-22	endogenous retrovirus group W member 1, envelope	Homo sapiens	145-148
16043495-4	2005	Strikingly, single nucleotide changes in this region were found to switch the peptide-binding specificity of the RRE from a bifunctional Rev- and RSG-1.2-binding mode to either a Rev-specific or a RSG-1.2- specific mode, demonstrating how an RNA can evolve alternative binding strategies in discrete steps without intermediate loss of function.	REV	137-140	ciliogenesis and planar polarity effector complex subunit 2	Homo sapiens	146-151
16043495-4	2005	Strikingly, single nucleotide changes in this region were found to switch the peptide-binding specificity of the RRE from a bifunctional Rev- and RSG-1.2-binding mode to either a Rev-specific or a RSG-1.2- specific mode, demonstrating how an RNA can evolve alternative binding strategies in discrete steps without intermediate loss of function.	REV	137-140	ciliogenesis and planar polarity effector complex subunit 2	Homo sapiens	197-202
11356012-5	2001	Twelve days after surgery the REV group had significantly lower weight gain and greater serum levels of NO, IL-2 and IL-6 than the CON and SHAM groups.	REV	30-33	interleukin 2	Rattus norvegicus	108-112
11356012-5	2001	Twelve days after surgery the REV group had significantly lower weight gain and greater serum levels of NO, IL-2 and IL-6 than the CON and SHAM groups.	REV	30-33	interleukin 6	Rattus norvegicus	117-121
11356012-8	2001	In the proximal small intestine the REV group had significantly increased protein levels and mucosal dry weights, but decreased interferon-gamma and IL-2 compared with the CON and SHAM groups.	REV	36-39	interferon gamma	Rattus norvegicus	128-144
11356012-8	2001	In the proximal small intestine the REV group had significantly increased protein levels and mucosal dry weights, but decreased interferon-gamma and IL-2 compared with the CON and SHAM groups.	REV	36-39	interleukin 2	Rattus norvegicus	149-153
10903508-6	2000	We demonstrated that Rev binds prothymosin alpha, and that prothymosin alpha binding to Rev but not to histone H1 was significantly enhanced in the presence of zinc and calcium ions.	REV	21-24	prothymosin alpha pseudogene 9	Homo sapiens	31-48
10903508-6	2000	We demonstrated that Rev binds prothymosin alpha, and that prothymosin alpha binding to Rev but not to histone H1 was significantly enhanced in the presence of zinc and calcium ions.	REV	88-91	prothymosin alpha pseudogene 9	Homo sapiens	59-76
7910642-6	1994	The presence of the Rev-responsive element (RRE) increased the efficiency of transfer of vectors containing significant lengths of gag sequence, as expected from the Rev requirement for nucleus-to-cytoplasm transport of unspliced vector RNA containing intact packaging signals.	REV	20-23	Pr55(Gag)	Human immunodeficiency virus 1	131-134
8116254-6	1994	A highly structured RNA element has been identified in the env gene of CAEV (nt 7850-8150); its structure and location suggested that it was analogous to the Rev-responsive element (RRE) of HIV-1 and visna virus.	REV	158-161	envelope polyprotein;trans-regulatory splicing-like protein	Caprine arthritis encephalitis virus	59-62
2827014-9	1988	There are 9 regions of homology between c-rel and v-rel, however, several differences exist between these genes, suggesting that transformation by REV-T results from the production of an altered v-rel protein.	REV	147-150	REL proto-oncogene, NF-kB subunit	Homo sapiens	40-45
29183075-10	2017	An additional 17 products (39%) contained another unapproved drug, including the growth hormone secretagogue ibutamoren, the peroxisome proliferator-activated receptor-delta agonist GW501516, and the Rev-ErbA agonist SR9009.	REV	200-203	thyroid hormone receptor alpha	Homo sapiens	204-208
16045742-2	2005	Recently, it has been found that Sam68, the substrate of Src associated in mitosis, is a functional homologue of Rev, and a synergistic activator of Rev activity.	REV	113-116	KH RNA binding domain containing, signal transduction associated 1	Homo sapiens	33-38
12853637-3	2003	In our previous study, we applied this combination to a non- redundant data set of env nucleotide sequences, confirmed the conservative secondary structure of the rev-responsive element (RRE) and found a new RNA structure in the first conserved (C1) region of the env gene.	REV	8-11	endogenous retrovirus group K member 20	Homo sapiens	83-86
12853637-3	2003	In our previous study, we applied this combination to a non- redundant data set of env nucleotide sequences, confirmed the conservative secondary structure of the rev-responsive element (RRE) and found a new RNA structure in the first conserved (C1) region of the env gene.	REV	8-11	endogenous retrovirus group K member 20	Homo sapiens	264-267
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	119-122	KH RNA binding domain containing, signal transduction associated 1	Homo sapiens	27-32
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	119-122	KH RNA binding domain containing, signal transduction associated 1	Homo sapiens	41-46
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	119-122	KH RNA binding domain containing, signal transduction associated 2	Homo sapiens	167-171
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	119-122	KH RNA binding domain containing, signal transduction associated 3	Homo sapiens	177-181
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	206-209	KH RNA binding domain containing, signal transduction associated 1	Homo sapiens	27-32
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	206-209	KH RNA binding domain containing, signal transduction associated 1	Homo sapiens	41-46
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	206-209	KH RNA binding domain containing, signal transduction associated 2	Homo sapiens	167-171
11483766-8	2001	The C-terminally truncated Sam68 mutant (Sam68DeltaC) previously observed to inhibit the Sam68-mediated stimulation of Rev activity (Reddy et al., 1999) also inhibits SLM1- and SLM2-mediated stimulation of Rev activity.	REV	206-209	KH RNA binding domain containing, signal transduction associated 3	Homo sapiens	177-181
31004257-6	2019	Furthermore, we observed that both REV and 5-fluorouracil (5-Fu) significantly reduce LPA-induced YB-1 phosphorylation and subsequent breast cancer invasion.	REV	35-38	Y-box binding protein 1	Homo sapiens	98-102
31004257-8	2019	Therefore, our data demonstrate that the YB-1/EZH2 signaling axis mediates LPA-induced AREG expression and breast cancer cell invasion and its inhibition by REV and 5-Fu, providing potential therapeutic targets and inhibition of breast cancer.	REV	157-160	Y-box binding protein 1	Homo sapiens	41-45
31004257-8	2019	Therefore, our data demonstrate that the YB-1/EZH2 signaling axis mediates LPA-induced AREG expression and breast cancer cell invasion and its inhibition by REV and 5-Fu, providing potential therapeutic targets and inhibition of breast cancer.	REV	157-160	enhancer of zeste 2 polycomb repressive complex 2 subunit	Homo sapiens	46-50