PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
15206926-6	2004	Purification by anionic interchange shows that the peroxidase inhibitor elutes like the two subtypes of inositol phosphoglycans (IPG)P and A, characterized as signal transducers of insulin action.	2-Isopropoxyethanol	129-132	insulin	Bos taurus	181-188
16145710-1	2005	The glycan structures of the major and more than ten minor populated isoforms of antithrombin (AT) were determined after separation of the isoforms by IEF using IPG strips.	2-Isopropoxyethanol	161-164	serpin family C member 1	Homo sapiens	81-93
16075418-0	2005	Optimization of IPG strip equilibration for the basic membrane protein mABC1.	2-Isopropoxyethanol	16-19	ATP-binding cassette, sub-family A (ABC1), member 1	Mus musculus	71-76
16075418-2	2005	Using a pressure-blotting approach, we demonstrate that a basic integral membrane protein, mitochondrial ATP-binding cassette protein 1 (mABC1), focuses in the IPG strip, but fails to enter into the 2-D SDS-PAGE gel.	2-Isopropoxyethanol	160-163	ATP-binding cassette, sub-family A (ABC1), member 1	Mus musculus	137-142
15276160-4	2004	Isoelectric focusing of native and 4HNE-modified cytochrome c using immobilized pH gradient (IpG) strips showed a decrease in the pI of the 4HNE-modified protein suggesting modification of charged amino acids.	2-Isopropoxyethanol	93-96	cytochrome c, somatic	Homo sapiens	49-61
10534758-6	1999	Our results support the existence in porcine thyroid cells of the GPI/IPG system, which can take part in TSH-dependent signal transduction processes.	2-Isopropoxyethanol	70-73	glucose-6-phosphate isomerase	Homo sapiens	66-69
14679575-1	2003	The isoforms distribution of the glycoprotein antithrombin III (ATIII) derived from human plasma was investigated by means of isoelectric focusing (IEF) in polyacrylamide gels with immobilized pH gradients (IPG) and two-dimensional gel electrophoresis (2-DE) as well as capillary electrophoretic methods.	2-Isopropoxyethanol	207-210	serpin family C member 1	Homo sapiens	46-62
10949152-3	2000	Comparing different pH ranges in immobilized pH gradient-isoelectric focusing (IPG-IEF), a range of pH 3 - 10 and 4 - 9 resulted in a highly defined and reproducible resolution of six different EF-2 variants of all extracts in the first dimension.	2-Isopropoxyethanol	79-82	eukaryotic translation elongation factor 2	Homo sapiens	194-198
10949152-7	2000	By application of a second IPG indicator strip to the 2-D gel, they could be aligned with corresponding spots in a silver-stained 2-D separation of human myocardial tissue, revealing that the EF-2 variants belong to the group of low-abundance proteins.	2-Isopropoxyethanol	27-30	eukaryotic translation elongation factor 2	Homo sapiens	192-196
10833332-3	2000	The significance of inhibitory effects of IPG A type on leptin release is important in relation to obesity and NIDDM in view of the action of leptin in promoting Lep expression and fat oxidation in muscle, in addition to its effects on satiety.	2-Isopropoxyethanol	42-45	leptin	Homo sapiens	162-165
14679575-1	2003	The isoforms distribution of the glycoprotein antithrombin III (ATIII) derived from human plasma was investigated by means of isoelectric focusing (IEF) in polyacrylamide gels with immobilized pH gradients (IPG) and two-dimensional gel electrophoresis (2-DE) as well as capillary electrophoretic methods.	2-Isopropoxyethanol	207-210	serpin family C member 1	Homo sapiens	64-69
10501653-8	1999	Pharmaceutical approaches using synthetically produced IPG analogues, which themselves mimic insulin"s actions, alone or in combination with other drugs, may lead the way toward introducing alternative therapies for type II diabetes in the coming years.	2-Isopropoxyethanol	55-58	insulin	Homo sapiens	93-100
7818988-7	1994	In the presence of suboptimal Epo concentrations, IPG has been found to potentiate Epo-induced CFU-E growth.	2-Isopropoxyethanol	50-53	erythropoietin	Rattus norvegicus	30-33
10212830-2	1998	While much work remains, the evidence has become strong that IPG generation following insulin action is a significant signaling mechanism.	2-Isopropoxyethanol	61-64	insulin	Homo sapiens	86-93
10212830-3	1998	A considerable body of data has established IPG release by insulin and other growth factors from cell membranes, cells and in human blood and muscle biopsies in vivo.	2-Isopropoxyethanol	44-47	insulin	Homo sapiens	59-66
9165224-8	1997	These data suggest that the pH 2.0 IPG plays an important role in mediating insulin"s effect on peripheral glucose utilization in man under physiological conditions.	2-Isopropoxyethanol	35-38	insulin	Homo sapiens	76-83
9150919-3	1997	Here we demonstrate the utility and efficacy of combining IPG 2-D gel electrophoresis with mass spectrometry to identify interferon-gamma- (IFN) and tumor necrosis factor (TNF)-regulated proteins in ME-180 cervical carcinoma cells.	2-Isopropoxyethanol	58-61	interferon alpha 1	Homo sapiens	121-144
7818988-1	1994	The involvement of a glycosylphosphatidylinositol/inositolphosphate glycan (GPI/IPG) system in the erythropoietin (Epo) signal transduction was investigated.	2-Isopropoxyethanol	80-83	erythropoietin	Rattus norvegicus	99-113
7818988-7	1994	In the presence of suboptimal Epo concentrations, IPG has been found to potentiate Epo-induced CFU-E growth.	2-Isopropoxyethanol	50-53	erythropoietin	Rattus norvegicus	83-86
7818988-1	1994	The involvement of a glycosylphosphatidylinositol/inositolphosphate glycan (GPI/IPG) system in the erythropoietin (Epo) signal transduction was investigated.	2-Isopropoxyethanol	80-83	erythropoietin	Rattus norvegicus	115-118
7818988-8	1994	These results support the hypothesis that a GPI/IPG based signal transduction system may be involved in Epo-induced cell proliferation.	2-Isopropoxyethanol	48-51	erythropoietin	Rattus norvegicus	104-107
7818988-3	1994	Incubation of these cells with Epo produced a rapid and transient hydrolysis of GPI with parallel release of IPG.	2-Isopropoxyethanol	109-112	erythropoietin	Rattus norvegicus	31-34
8305428-2	1994	Purified 5"-nucleotidase were then cleaved by cyanogen bromide (CNBr), and then inositol phosphoglycan-containing C-terminal peptides (IPG peptides) were separated by C18 reverse-phase liquid chromatography and analyzed by peptide sequencer, amino acid analyzer, gas chromatography (GC), and GC-mass spectrometry (MS).	2-Isopropoxyethanol	135-138	5'-nucleotidase	Bos taurus	9-24
7818988-4	1994	IPG production was Epo dose dependent and the maximal effect was obtained with the same concentration of Epo which gave the maximal mitogenic effect, i.e. 1 U/ml.	2-Isopropoxyethanol	0-3	erythropoietin	Rattus norvegicus	19-22
7818988-4	1994	IPG production was Epo dose dependent and the maximal effect was obtained with the same concentration of Epo which gave the maximal mitogenic effect, i.e. 1 U/ml.	2-Isopropoxyethanol	0-3	erythropoietin	Rattus norvegicus	105-108
33677446-7	2021	RESULTS: Between 2017 and 2020, we had 6 patients with a high risk of withdrawal syndrome in whom an infected IPG with cables was removed and replaced on the opposite side in the same session.	2-Isopropoxyethanol	110-113	Cdk5 and Abl enzyme substrate 1	Homo sapiens	119-125
1654553-8	1991	It had biological effects similar to those reported for the insulin-induced IPG in other tissues.	2-Isopropoxyethanol	76-79	insulin	Homo sapiens	60-67
34406916-5	2021	Exploring serum profile also showed a significant increase of IL-1alpha, IL-1beta, IL-6, TNF-alpha, MDA and NO in IPG compared to their correspond values in NIPG and CG.	2-Isopropoxyethanol	114-117	interleukin-1 alpha	Ovis aries	62-71
34406916-5	2021	Exploring serum profile also showed a significant increase of IL-1alpha, IL-1beta, IL-6, TNF-alpha, MDA and NO in IPG compared to their correspond values in NIPG and CG.	2-Isopropoxyethanol	114-117	interleukin-1 alpha	Ovis aries	73-81
34406916-5	2021	Exploring serum profile also showed a significant increase of IL-1alpha, IL-1beta, IL-6, TNF-alpha, MDA and NO in IPG compared to their correspond values in NIPG and CG.	2-Isopropoxyethanol	114-117	interleukin-6	Ovis aries	83-87
34406916-5	2021	Exploring serum profile also showed a significant increase of IL-1alpha, IL-1beta, IL-6, TNF-alpha, MDA and NO in IPG compared to their correspond values in NIPG and CG.	2-Isopropoxyethanol	114-117	tumor necrosis factor	Ovis aries	89-98
34181493-5	2021	The IPG effect on the AGF characteristics of slope, threshold, dynamic range, and stimulus level at 50% maximum eCAP amplitude (level50%) was investigated.	2-Isopropoxyethanol	4-7	angiopoietin like 6	Homo sapiens	22-25
34181493-6	2021	AGF threshold and level50% were significantly affected by the IPG in both EAS and control group.	2-Isopropoxyethanol	62-65	angiopoietin like 6	Homo sapiens	0-3
34181493-8	2021	In contrast, the change of the AGF characteristics with increasing IPG was independent of these electrode-specific measures.	2-Isopropoxyethanol	67-70	angiopoietin like 6	Homo sapiens	31-34
34181493-9	2021	The IPG effect on the AGF level50% in both groups, as well as on the threshold in EAS users, correlated with the duration of hearing loss, which is a predictor of neural health.	2-Isopropoxyethanol	4-7	angiopoietin like 6	Homo sapiens	22-25
34181493-11	2021	This outcome is consistent with our hypothesis that the influence of IPG effects on AGF characteristics provides a sensitive measurement and may indicate better neural health in the apex compared to the medial cochlear region in EAS users.	2-Isopropoxyethanol	69-72	angiopoietin like 6	Homo sapiens	84-87
8375721-1	1993	The analysis of prenatal care was taken of 67 adolescent"s who delivered in Obstetric Clinic IPG PAM in Szczecin, during the period 1990-1992.	2-Isopropoxyethanol	93-96	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	97-100
2156818-2	1990	A class of inositol phosphate-containing oligosaccharides (IPG) derived from a membrane glycan-phosphatidylinositol precursor (GPI) has been identified as a possible mediator of insulin action.	2-Isopropoxyethanol	59-62	insulin	Homo sapiens	178-185
2156818-4	1990	Herein we have established this method in rat and human liver microsomes, it being our end point to evaluate if the pool of GPI was normal in diabetes and if failure of insulin to generate IPG from GPI could be involved in the mechanism of insulin resistance in Type II diabetes.	2-Isopropoxyethanol	189-192	insulin	Homo sapiens	169-176
2313199-1	1990	A method for analytical isoelectric focusing (IEF) of apolipoprotein E (apoE) in immobilized pH gradients (IPG) and immunodetection of the separated isoforms has been developed for use with either very low density lipoproteins (VLDL) or whole plasma.	2-Isopropoxyethanol	107-110	apolipoprotein E	Homo sapiens	72-76
2313199-6	1990	Finally, the conditions for IPG of whole plasma using apoE monoclonal antibodies and enzyme-conjugated anti-mouse IgG for detection were established.	2-Isopropoxyethanol	28-31	apolipoprotein E	Homo sapiens	54-58
2313199-7	1990	Thus, IPG focusing is shown to be a powerful method for resolution of the apoE sialoforms and apoE mutant forms.	2-Isopropoxyethanol	6-9	apolipoprotein E	Homo sapiens	74-78
2313199-7	1990	Thus, IPG focusing is shown to be a powerful method for resolution of the apoE sialoforms and apoE mutant forms.	2-Isopropoxyethanol	6-9	apolipoprotein E	Homo sapiens	94-98
35625456-8	2022	Interestingly, IPG increased SOD activity (89.27%) and reduced MDA levels (35.53%), as well as displayed anti-inflammatory activity by decreasing TNF-alpha (88.77%), IL-1beta (62.87%), and C-reactive protein (56.41%) levels.	2-Isopropoxyethanol	15-18	tumor necrosis factor	Mus musculus	146-155
35625456-8	2022	Interestingly, IPG increased SOD activity (89.27%) and reduced MDA levels (35.53%), as well as displayed anti-inflammatory activity by decreasing TNF-alpha (88.77%), IL-1beta (62.87%), and C-reactive protein (56.41%) levels.	2-Isopropoxyethanol	15-18	interleukin 1 alpha	Mus musculus	166-174
35625456-8	2022	Interestingly, IPG increased SOD activity (89.27%) and reduced MDA levels (35.53%), as well as displayed anti-inflammatory activity by decreasing TNF-alpha (88.77%), IL-1beta (62.87%), and C-reactive protein (56.41%) levels.	2-Isopropoxyethanol	15-18	C-reactive protein, pentraxin-related	Mus musculus	189-207
34980610-4	2022	This protocol describes an original innovative multicentre international study aimed to assess safety and efficacy of aDBS vs cDBS using a new generation of DBS IPG in PD (AlphaDBS system by Newronika SpA, Milan, Italy).	2-Isopropoxyethanol	161-164	surfactant protein A1	Homo sapiens	201-204
3243260-1	1988	The genetic variants of tomato acid phosphatase (Aps-1) systems have been analyzed by isoelectric focusing in immobilized pH gradients (IPG).	2-Isopropoxyethanol	136-139	acid phosphatase 1	Solanum lycopersicum	31-47
3243260-1	1988	The genetic variants of tomato acid phosphatase (Aps-1) systems have been analyzed by isoelectric focusing in immobilized pH gradients (IPG).	2-Isopropoxyethanol	136-139	acid phosphatase 1	Solanum lycopersicum	49-54
3243260-2	1988	By using an ultranarrow pH 4.25-4.55 IPG gel, the two genotypes Aps-1(1) and Aps-1+, differentiating tomato variants into nematode-resistant or nematode-susceptible plants, are separated into two sharp zones over a distance of 2.5 cm with isoelectric points of 4.37 and 4.43, respectively.	2-Isopropoxyethanol	37-40	acid phosphatase 1	Solanum lycopersicum	64-69
2457608-3	1988	For alpha 2-M, IPG on a 4-6.5 gradient followed by enzyme-linked immunodetection allows the recognition of a complex pattern with several bands centered around pI 5.1.	2-Isopropoxyethanol	15-18	alpha-2-macroglobulin	Homo sapiens	4-13
33126525-9	2020	Regarding IPG effect and pulse-train responses, the BDNF-treated animals exhibited more normal responses than both untreated and THF-treated animals.	2-Isopropoxyethanol	10-13	Bdnf	Cavia porcellus	52-56
27681761-11	2016	An iPG NTCP threshold of 20% and 30% predicted NTCP benefits for the P60 and C70 plans, respectively (P<.001).	2-Isopropoxyethanol	3-6	sequestosome 1	Homo sapiens	69-72
33073226-10	2020	From the GSEA analysis of the biological function of genes related to IPG, it was found that the genes of the high-risk group were enriched in some tumorigenesis related pathways, such as DNA replication, cell cycle, and PPARA.	2-Isopropoxyethanol	70-73	peroxisome proliferator activated receptor alpha	Homo sapiens	221-226
30448218-5	2019	The tumors in IPG VII with HNF1beta+/p53+/ARID1A+ immunophenotype demonstrated a significantly worse overall survival and progression-free survival as compared with the other IPGs.	2-Isopropoxyethanol	14-17	HNF1 homeobox B	Homo sapiens	27-35
30448218-5	2019	The tumors in IPG VII with HNF1beta+/p53+/ARID1A+ immunophenotype demonstrated a significantly worse overall survival and progression-free survival as compared with the other IPGs.	2-Isopropoxyethanol	14-17	tumor protein p53	Homo sapiens	37-40
30448218-5	2019	The tumors in IPG VII with HNF1beta+/p53+/ARID1A+ immunophenotype demonstrated a significantly worse overall survival and progression-free survival as compared with the other IPGs.	2-Isopropoxyethanol	14-17	AT-rich interaction domain 1A	Homo sapiens	42-48
27681761-13	2016	Furthermore, for the iPG, a vPTV56 >13% predicted benefit with P60 (P<.001) and C70 (P=.002).	2-Isopropoxyethanol	21-24	sequestosome 1	Homo sapiens	66-69
28519632-8	2012	For lead+Ext.+IPG, 0.4 C change was observed with T/R head coil and 0.95 C with T/R body coil for 3D MPRAGE (low SAR).	2-Isopropoxyethanol	14-17	sarcosine dehydrogenase	Homo sapiens	113-116
20959063-3	2010	METHODS: The total proteins of L9981 and L9981-nm23-H1 were separated by immobilized pH gradient (IPG)-based 2-dimensional electrophoresis (2-DE); the significantly differently expressed proteins were examined by mass spectrometry and analyzed by bioinformatics.	2-Isopropoxyethanol	98-101	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	47-54
19621512-6	2009	Compared with NGT group and IGT + IPG group, insulin secretion index at 30 min and homeostasis model assessment-insulin secretion index were significantly lower in PTDM group (P < 0.05).	2-Isopropoxyethanol	34-37	insulin	Homo sapiens	45-52
17987632-5	2007	2-DE using a narrow-range IPG 4-7 strips in the first dimension and linear 15% SDS-PAGE in the second allowed to separate different SOD1 spots.	2-Isopropoxyethanol	26-29	superoxide dismutase 1	Homo sapiens	132-136
26587192-6	2015	The mean CRP levels at post-lead implantation day 2 were further elevated at post-IPG implantation day 2 (3.41+-2.56 mg/dL, n=46, respectively, p<0.01).	2-Isopropoxyethanol	82-85	C-reactive protein	Homo sapiens	9-12
26587192-8	2015	Mean CRP levels after IPG implantation were significantly higher in patients whose IPGs were implanted at post-lead day 3 than those at post-lead day 5-6 (3.99+-2.80 mg/dL, n=30, and 2.31+-1.56 mg/dL, n=16, respectively, p<0.05).	2-Isopropoxyethanol	22-25	C-reactive protein	Homo sapiens	5-8
26587192-10	2015	CONCLUSION: The mean postoperative CRP levels were highest on post-IPG insertion day 2 and decreased rapidly, returning to the normal range on post-IPG implantation day 6.	2-Isopropoxyethanol	67-70	C-reactive protein	Homo sapiens	35-38
26587192-10	2015	CONCLUSION: The mean postoperative CRP levels were highest on post-IPG insertion day 2 and decreased rapidly, returning to the normal range on post-IPG implantation day 6.	2-Isopropoxyethanol	148-151	C-reactive protein	Homo sapiens	35-38
26587192-11	2015	The duration of post-lead implantation period influenced the magnitude of CRP elevation at post-IPG insertion day 2.	2-Isopropoxyethanol	96-99	C-reactive protein	Homo sapiens	74-77
23429403-6	2013	Root gravitropism, PIN2 (an auxin efflux carrier) abundance, H+ efflux or Ca2+ influx in root apexes, were weaker in IPG-grown roots than those in TPG-grown roots.	2-Isopropoxyethanol	117-120	Auxin efflux carrier family protein	Arabidopsis thaliana	19-23
17664885-2	2007	Inositol phosphoglycan A-type (A-IPG), a putative second messenger of insulin, was reported to regulate lipogenesis in adipose tissue.	2-Isopropoxyethanol	33-36	insulin	Homo sapiens	70-77