PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11162836-2	2001	NS2 shares these features with the nonstructural protein, NSP2, of rotavirus, which like BTV is a member of the family Reoviridae.	CHEMBL3972792	89-92	NS2	Homo sapiens	0-3
20422571-3	2004	Phylogenetic analysis of the NS3/NS3A gene segregated these Greek isolates of BTV into two monophyletic groups.	CHEMBL3972792	78-81	KRAS proto-oncogene, GTPase	Homo sapiens	29-32
19831310-3	2009	In this report, after cell infection with BTV, the activation of caspase 8 was detected, proving the extrinsic receptor binding apoptotic pathway.	CHEMBL3972792	42-45	caspase 8	Homo sapiens	65-74
19831310-5	2009	Furthermore, its translocation to the mitochondria, as well as the release of cytochrome c and Smac/Diablo confirmed that BTV apoptosis involves the sequential intrinsic pathway.	CHEMBL3972792	122-125	cytochrome c, somatic	Homo sapiens	78-90
19831310-5	2009	Furthermore, its translocation to the mitochondria, as well as the release of cytochrome c and Smac/Diablo confirmed that BTV apoptosis involves the sequential intrinsic pathway.	CHEMBL3972792	122-125	diablo IAP-binding mitochondrial protein	Homo sapiens	95-99
19831310-5	2009	Furthermore, its translocation to the mitochondria, as well as the release of cytochrome c and Smac/Diablo confirmed that BTV apoptosis involves the sequential intrinsic pathway.	CHEMBL3972792	122-125	diablo IAP-binding mitochondrial protein	Homo sapiens	100-106
15233536-3	2004	Along with the BTV data, we also discuss the thermodynamics of the temperature dependence of the BTV through a two-parameter equation In (BTV) = A1/T + C1 where T is temperature (K), A1 = -deltaH/R where deltaH is enthalpy of sorption and C1 is constant.	CHEMBL3972792	97-100	BCL2 related protein A1	Homo sapiens	145-154
15233536-3	2004	Along with the BTV data, we also discuss the thermodynamics of the temperature dependence of the BTV through a two-parameter equation In (BTV) = A1/T + C1 where T is temperature (K), A1 = -deltaH/R where deltaH is enthalpy of sorption and C1 is constant.	CHEMBL3972792	97-100	BCL2 related protein A1	Homo sapiens	145-154
11162836-2	2001	NS2 shares these features with the nonstructural protein, NSP2, of rotavirus, which like BTV is a member of the family Reoviridae.	CHEMBL3972792	89-92	reticulon 2	Homo sapiens	58-62
1381538-2	1992	The chimeric protein formed BTV core-like particles (CLPs) in Spodoptera frugiperda cells only when the cells were coinfected with this recombinant virus and a recombinant baculovirus that expresses unmodified VP7 and VP3 of BTV.	CHEMBL3972792	28-31	colipase	Homo sapiens	53-57
9712508-1	1998	The sequence of the S10 gene segment of the United States prototype strains of BTV serotypes 10, 11, 13, and 17 obtained from the American Type Culture Collection (ATCC), the commercial modified live virus vaccine strains of BTV serotypes 10, 11, and 17, and 20 field isolates of BTV serotypes 10, 11, 13, and 17 was determined to better define the molecular epidemiology of BTV infection in the US.	CHEMBL3972792	79-82	ribosomal protein S10	Homo sapiens	20-23
9712508-3	1998	Nucleotide differences between the S10 genes from field isolates of BTV ranged from zero (100% identity) to 142 (81.8% identity).	CHEMBL3972792	68-71	ribosomal protein S10	Homo sapiens	35-38
9712508-6	1998	This apparent conservation of NS3/NS3A amongst different strains and serotypes of BTV likely is a reflection of functional constraints on the protein that tolerate little variation.	CHEMBL3972792	82-85	KRAS proto-oncogene, GTPase	Homo sapiens	30-33
9712508-7	1998	The various US isolates of BTV segregate into two distinct monophyletic groups based on their S10 gene sequences and clustering of viruses was independent of serotype, year of isolation, geographical origin, and of host species of isolation.	CHEMBL3972792	27-30	ribosomal protein S10	Homo sapiens	94-97
7683160-4	1993	Selective binding of those lectins which have well-defined sugar specificities suggests that the potential short N-linked carbohydrate chain present on BTV VP5 might be composed of sialic acid alpha(2-6)-N-acetylgalactosamine-beta(1-3)-galactose-beta(1-4)-N- acetylglucosamine-beta(1-2)-mannose-N-acetylglucosamine-Asn.	CHEMBL3972792	152-155	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	226-234
7683160-4	1993	Selective binding of those lectins which have well-defined sugar specificities suggests that the potential short N-linked carbohydrate chain present on BTV VP5 might be composed of sialic acid alpha(2-6)-N-acetylgalactosamine-beta(1-3)-galactose-beta(1-4)-N- acetylglucosamine-beta(1-2)-mannose-N-acetylglucosamine-Asn.	CHEMBL3972792	152-155	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	246-254
7683160-4	1993	Selective binding of those lectins which have well-defined sugar specificities suggests that the potential short N-linked carbohydrate chain present on BTV VP5 might be composed of sialic acid alpha(2-6)-N-acetylgalactosamine-beta(1-3)-galactose-beta(1-4)-N- acetylglucosamine-beta(1-2)-mannose-N-acetylglucosamine-Asn.	CHEMBL3972792	152-155	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	277-285
29778186-4	2018	VP2 is an important outer shell protein that defines BTV serotypes and is, therefore, an ideal target antigen for serotype identification.	CHEMBL3972792	53-56	VP2	Bluetongue virus	0-3
32249640-6	2020	Among all, the compounds which are selected based on their dock scores such as 5A, 5F, 5G, 5H, 5I, and 5K against NDV and 5J, 5E, 5I, 5C, 5A, and 5K against BTV have shown significant antiviral activity against HN protein of NDV, VP7 protein of Bluetongue virus in both NDV- and BTV-treated embryonated eggs and BHK 21 cell lines.	CHEMBL3972792	279-282	VP7	Bluetongue virus	230-233
27448505-6	2016	The study indicated the potential utility of rNS3DeltaHD fusion protein as candidate diagnostic reagent in developing an indirect-ELISA for sero-surveillance of animals for BTV antibodies under DIVA strategy, wherever monovalent/polyvalent killed BT vaccine formulations devoid of NS proteins are being practiced for immunization.	CHEMBL3972792	173-176	mal, T-cell differentiation protein	Rattus norvegicus	45-49
21840139-8	2012	The secretion of interferon gamma (IFN-gamma) in ELISPOT after in vitro re-stimulation of PBMC of BTV-8 vaccinated animals with BTV was evaluated in the field for the first time.	CHEMBL3972792	98-101	interferon gamma	Bos taurus	17-44
27511827-3	2016	Adsorption capacity of MOF-199 and two sorbents, when assessed for the 13 odorants at a 10% breakthrough volume (BTV), was 22.6  +-  42.3, 0.70  +-  1.08, and 11.0  +-  18.3 mug g(-1), respectively.	CHEMBL3972792	113-116	lysine acetyltransferase 8	Homo sapiens	23-26
27511827-4	2016	The adsorption capacity (mug g(-1)) assessed at 10% BTV showed the superiority of MOF-199 towards phenolic and indolic compounds (such as o-C (0.31  +-  0.04), PhAl (61.6  +-  4.98), p-C (140  +-  7.95), ID (27.8  +-  2.23), and SK (63.9  +-  1.55)), demonstrating the feasibility of MOF as sorption media for treating certain nuisance components.	CHEMBL3972792	52-55	lysine acetyltransferase 8	Homo sapiens	82-85
23007876-4	2012	The results show that BTV infection of sheep led to enhanced transcription of iNOS in PBMCs and in particular RLOs.	CHEMBL3972792	22-25	nitric oxide synthase, inducible	Ovis aries	78-82
23007876-5	2012	The BTV RNAs and/or antigens were readily demonstrable in these mononuclear leukocytes, suggesting the possible role of BTV in iNOS induction.	CHEMBL3972792	4-7	nitric oxide synthase, inducible	Ovis aries	127-131
22305933-6	2012	Less BTV was irradiated using electrons than photons in 29% (CT1) to 37% (CT2).	CHEMBL3972792	5-8	cardiotrophin 1	Homo sapiens	61-64
22305933-6	2012	Less BTV was irradiated using electrons than photons in 29% (CT1) to 37% (CT2).	CHEMBL3972792	5-8	cancer/testis antigen 2	Homo sapiens	74-77