PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2618079-4	1989	Exposure of aniline-metabolizing hepatocytes to p-chloro-mercuribenzoate (PCMB) or p-chloromercuribenzenesulphonic acid (PCMBS) resulted in decreased levels of cytochrome P-450, decreased glucuronidation of 4-aminophenol and increased levels of free 4-aminophenol.	PCMBS	121-126	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	160-176
2618079-13	1989	PCMB and PCMBS inhibited aniline metabolism, probably by binding to a cysteinyl-SH residue in cytochrome P-450 apoenzyme and "active sites" of UDP-glucuronyl transferases.	PCMBS	9-14	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	94-110
2849421-5	1988	Treatment of membrane vesicles with p-chloromercuribenzenesulphonate (PCMBS), which inhibited 125I-RBP binding, also inhibited the uptake of retinol from RBP, but the uptake of free retinol was unaffected.	PCMBS	70-75	retinol binding protein 4	Homo sapiens	99-102
2849421-5	1988	Treatment of membrane vesicles with p-chloromercuribenzenesulphonate (PCMBS), which inhibited 125I-RBP binding, also inhibited the uptake of retinol from RBP, but the uptake of free retinol was unaffected.	PCMBS	70-75	retinol binding protein 4	Homo sapiens	154-157
2849421-6	1988	Addition of PCMBS after the attainment of steady-state uptake equilibrium abolished the binding of RBP, but did not affect the retinol already taken up from RBP.	PCMBS	12-17	retinol binding protein 4	Homo sapiens	99-102
11468359-10	2001	Alternative explanations such as passage of pCMBS across the AQP1 tetramer center or other unspecified transmembrane pathways cannot be excluded.	PCMBS	44-49	aquaporin 1 (Colton blood group) L homeolog	Xenopus laevis	61-65
6361013-10	1983	The enzyme was completely inhibited by 10(-7) M p-chloromercuribenzoic acid (pCMB), 10(-7) M p-chloromercuriphenylsulfonic acid (pCMPS), and 10(-4) M diisopropyl phosphofluoridate (DFP), but not by 1 mM E-64, which is known as an inhibitor specific to thiol proteinase.	PCMBS	129-134	endogenous retrovirus group K member 18	Homo sapiens	258-268
23546606-2	2013	MCT8 contains 10 residues of the reactive amino acid cysteine (Cys) whose functional roles were studied using the Cys-specific reagent p-chloromercurybenzenesulfonate (pCMBS) and by site-directed mutagenesis.	PCMBS	168-173	solute carrier family 16 member 2	Homo sapiens	0-4
2833496-6	1988	para-Chloromercuriphenylsulfonate, an inhibitor of CE and triglyceride transfer, was found to decrease the binding of radiolabeled CE and triglyceride by CETP.	PCMBS	0-33	cholesteryl ester transfer protein	Homo sapiens	154-158
6097490-1	1984	Incorporation of p-chloromercuribenzene sulphonate (PCMBS) (1mM) in the assay medium for rat hepatic lactogenic receptor produced complete inhibition of binding of [125I]oPRL to the membrane.	PCMBS	52-57	opioid related nociceptin receptor 1	Rattus norvegicus	170-174
6097490-3	1984	Pretreatment of rat hepatic membrane with PCMBS inhibited the binding of [125I]oPRL but not that of [125I]bGH.	PCMBS	42-47	opioid related nociceptin receptor 1	Rattus norvegicus	79-83
6097490-4	1984	The lactogenic receptor binding inhibition by PCMBS pretreatment was both concentration- and time-dependent, with complete inhibition at 0.5 mM for 60 min at 0 degrees C. Scatchard analysis of [125I]oPRL binding to membrane at 50% inhibition by PCMBS (0.11 mM) revealed that the binding capacity was decreased rather than the binding affinity.	PCMBS	46-51	opioid related nociceptin receptor 1	Rattus norvegicus	199-203
14979872-2	2004	mOAT1-mediated transport of organic anion PAH ( p -aminohippurate) in HeLa cells was inhibited by the cysteine-modifying reagent PCMBS (p-chloromercuribenzenesulphonate).	PCMBS	129-134	solute carrier family 22 (organic anion transporter), member 6	Mus musculus	0-5
12199709-2	2002	We found that a cysteine-specific reagent, p-chloromercuriphenylsulfonic acid (PCMPS), irreversibly inhibited one of the isozymes (GalNAc-T1).	PCMBS	79-84	polypeptide N-acetylgalactosaminyltransferase 1	Homo sapiens	131-140
11748229-5	2002	Cys(501), located in the hydrophobic C-terminal membrane-spanning domain of eNTPDase3, was found to be the site of chemical modification by a sulfhydryl-specific reagent, p-chloromercuriphenylsulfonic acid (pCMPS), leading to inhibition of enzyme activity.	PCMBS	207-212	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	76-85
10591077-2	1999	In this study, we have investigated the roles of these extracellular cysteine residues in mediating inhibition of the Kir2.3 channel by the cysteine-reactive reagents para-chloromercuribenzenesulphonate (PCMBS) and thimerosal, and the oxidizing agent hydrogen peroxide (H2O2).	PCMBS	204-209	potassium inwardly rectifying channel subfamily J member 4 S homeolog	Xenopus laevis	118-124
10548552-3	1999	NaDC-1 is sensitive to inhibition by the impermeant cysteine-specific reagent, p-chloromercuribenzenesulphonate (pCMBS).	PCMBS	113-118	solute carrier family 13 member 2	Homo sapiens	0-6
10548552-4	1999	The pCMBS-sensitive residues in NaDC-1 are Cys-227, found in transmembrane domain 5, and Cys-476, located in transmembrane domain 9.	PCMBS	4-9	solute carrier family 13 member 2	Homo sapiens	32-38
10591077-6	1999	Wild-type Kir2.3 currents were significantly inhibited by PCMBS, thimerosal and H2O2.	PCMBS	58-63	potassium inwardly rectifying channel subfamily J member 4 S homeolog	Xenopus laevis	10-16
10591077-7	1999	Currents for mutants Kir2.3 C79S and C140S were also inhibited by PCMBS, thimerosal and H2O2.	PCMBS	66-71	potassium inwardly rectifying channel subfamily J member 4 S homeolog	Xenopus laevis	21-27
1696788-7	1990	The mercurial reagent, para-chloromercuribenzenesulfonate (PCMBS), which inhibits ADH-stimulated transepithelial PF in intact bladders by 50-60%, inhibited vesicle PH+ by 55%.	PCMBS	59-64	arginine vasopressin	Homo sapiens	82-85
2164127-1	1990	5,5-Dithiobis-(2-nitrobenzoic acid) (DTNB) and p-chloro-mercuriphenylsulfonic acid (PCMPS) are well-known sulfhydryl inhibitors that are used to inhibit lecithin: cholesterol acyltransferase (LCAT).	PCMBS	84-89	lecithin-cholesterol acyltransferase	Homo sapiens	153-190
2164127-1	1990	5,5-Dithiobis-(2-nitrobenzoic acid) (DTNB) and p-chloro-mercuriphenylsulfonic acid (PCMPS) are well-known sulfhydryl inhibitors that are used to inhibit lecithin: cholesterol acyltransferase (LCAT).	PCMBS	84-89	lecithin-cholesterol acyltransferase	Homo sapiens	192-196