PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9218726-0	1997	Hot-spot mutations in the p53 gene of liver nodules induced in rats fed DL-ethionine with a methyl-deficient diet.	DL-ETHIONINE	72-84	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	26-29
35336871-5	2022	Interestingly, SUMOylation at SUMO conjugation site (SCS) K104 is negatively regulated by another multifunctional HAdV-C5 protein, E4orf6, which is known to form a complex with E1B-55K.	DL-ETHIONINE	58-62	small nucleolar RNA, H/ACA box 73A	Homo sapiens	177-180
65785-0	1977	Increased alpha-fetoprotein biosynthesis in rats following DL-ethionine and carbon tetrachloride injuries.	DL-ETHIONINE	59-71	alpha-fetoprotein	Rattus norvegicus	10-27
3498118-1	1987	DL-ethionine increases the activity of liver biotinidase, an enzyme which hydrolyzes biotinylesters and biotinylpeptides.	DL-ETHIONINE	0-12	biotinidase	Rattus norvegicus	45-56
3498118-2	1987	Chronic DL-ethionine feeding increases transiently the activity of biotinidase in mouse and rat liver, after which it remains elevated in the serum.	DL-ETHIONINE	8-20	biotinidase	Mus musculus	67-78
3498118-3	1987	In the present work we show that both isomers of DL-ethionine are equally good enhancers of the liver biotinidase, while, 3-ethylthiopropionate, the toxic metabolite of DL-ethionine, has no effect on the biotinidase activity of either liver or serum.	DL-ETHIONINE	49-61	biotinidase	Rattus norvegicus	102-113
6138146-0	1983	Dose and sex dependent effects of 2-acetylaminofluorene, 3"-methyl-4-dimethylaminoazobenzene and DL-ethionine in induction of gamma-glutamyl transpeptidase-positive liver cell foci in rats.	DL-ETHIONINE	97-109	gamma-glutamyltransferase 1	Rattus norvegicus	126-155
3589149-2	1987	The liver of rats, pretreated by DL-ethionine feeding, incorporated--after injection of 20 mg L-ethionine/100 g body wt.--six times more C-14 from glycine-2-14C into the adenosyl-moiety of SAE than normal rats.	DL-ETHIONINE	33-45	anti-Mullerian hormone receptor type 2	Rattus norvegicus	137-141
6177022-1	1982	Serum alpha-fetoprotein (AFP) concentrations increased promptly 2 days following a single injection of DL-ethionine (ethionine) in adult female rats.	DL-ETHIONINE	103-115	alpha-fetoprotein	Rattus norvegicus	6-23
6177022-1	1982	Serum alpha-fetoprotein (AFP) concentrations increased promptly 2 days following a single injection of DL-ethionine (ethionine) in adult female rats.	DL-ETHIONINE	103-115	alpha-fetoprotein	Rattus norvegicus	25-28
6179139-1	1982	Rats fed on a diet containing 0.25% DL-ethionine (ethionine), which has been usually used as carcinogenic dose, demonstrated the early elevations of serum alpha-fetoprotein (AFP) approximately in week 6 of the feedings.	DL-ETHIONINE	36-48	alpha-fetoprotein	Rattus norvegicus	155-172
6179139-1	1982	Rats fed on a diet containing 0.25% DL-ethionine (ethionine), which has been usually used as carcinogenic dose, demonstrated the early elevations of serum alpha-fetoprotein (AFP) approximately in week 6 of the feedings.	DL-ETHIONINE	36-48	alpha-fetoprotein	Rattus norvegicus	174-177
65785-1	1977	The incorporation of 14C-leucine into alpha-fetoprotein (AFP) in serum and liver extracts from DL-ethionine and carbon tetrachloride (CCl4)-injured rats was measured directly by using an immunochemical technique.	DL-ETHIONINE	95-107	alpha-fetoprotein	Rattus norvegicus	38-55
65785-1	1977	The incorporation of 14C-leucine into alpha-fetoprotein (AFP) in serum and liver extracts from DL-ethionine and carbon tetrachloride (CCl4)-injured rats was measured directly by using an immunochemical technique.	DL-ETHIONINE	95-107	alpha-fetoprotein	Rattus norvegicus	57-60
58843-2	1976	Marked elevations of serum AFP concentrations occurred within 4 days in both male and female rats after administration of DL-ethionine or L-ethionine, although the increased levels of serum AFP and liver triglyceride in the adults were less marked in the male than in the female.	DL-ETHIONINE	122-134	alpha-fetoprotein	Rattus norvegicus	27-30
58843-2	1976	Marked elevations of serum AFP concentrations occurred within 4 days in both male and female rats after administration of DL-ethionine or L-ethionine, although the increased levels of serum AFP and liver triglyceride in the adults were less marked in the male than in the female.	DL-ETHIONINE	122-134	alpha-fetoprotein	Rattus norvegicus	190-193
31295632-4	2019	Oxidations of dl-ethionine by Pt(IV) anticancer model complexes trans-[PtX2(CN4)]2- (X = Cl or Br) were thus analyzed by time-resolved and stopped-flow spectral techniques.	DL-ETHIONINE	14-26	paired like homeodomain 2	Homo sapiens	71-75
168749-3	1975	Administration of DL-ethionine prior to 3-methylcholanthrene treatment effectively blocks any increase in benzypyrene hydroxylase and cytochrome P-450 but not the increase in the levels of the high-spin species of the hemoprotein normally seen following 3-methylcholanthrene induction.	DL-ETHIONINE	18-30	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	134-150
13808284-0	1959	[Influence of administration of DL-ethionine on the enzymatic adaptation of hepatic glucose-6-phosphatase in the rat].	DL-ETHIONINE	32-44	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	84-105
14016606-0	1961	[Liver catalase in the rat treated with DL-ethionine].	DL-ETHIONINE	40-52	catalase	Rattus norvegicus	7-15
27176741-8	2016	In addition to K104 we identified further acetylation sites in K-Ras 4B, including K147, within the important G5/SAK-motif.	DL-ETHIONINE	15-19	KRAS proto-oncogene, GTPase	Homo sapiens	63-71
29174981-7	2018	Excitingly, Lys-104 (K104), a previously identified lysine acetylation site of TIP60 with unknown function, was observed to be indispensable for inducing p53-mediated apoptosis under low glucose condition.	DL-ETHIONINE	21-25	lysine acetyltransferase 5	Homo sapiens	79-84
29174981-7	2018	Excitingly, Lys-104 (K104), a previously identified lysine acetylation site of TIP60 with unknown function, was observed to be indispensable for inducing p53-mediated apoptosis under low glucose condition.	DL-ETHIONINE	21-25	tumor protein p53	Homo sapiens	154-157
23118980-5	2012	Here we report that NEDD8 is conjugated to RCAN1 (RCAN1-1S) via three lysine residues, K96, K104, and K107.	DL-ETHIONINE	92-96	NEDD8 ubiquitin like modifier	Homo sapiens	20-25
23118980-5	2012	Here we report that NEDD8 is conjugated to RCAN1 (RCAN1-1S) via three lysine residues, K96, K104, and K107.	DL-ETHIONINE	92-96	regulator of calcineurin 1	Homo sapiens	43-48
23118980-5	2012	Here we report that NEDD8 is conjugated to RCAN1 (RCAN1-1S) via three lysine residues, K96, K104, and K107.	DL-ETHIONINE	92-96	regulator of calcineurin 1	Homo sapiens	50-58
16899234-8	2007	On the other hand, prolidase activity against glycylproline was enhanced by L-methionine, D-methionine, D,L-methionine, D,L-homocysteine thiolactone and D,L-ethionine.	DL-ETHIONINE	153-166	peptidase D	Homo sapiens	19-28
16899234-10	2007	CONCLUSION: The prolinase activity in normal and prolidase-deficient erythrocyte lysates was inhibited by L-methionine, D,L-ethionine and D,L-homocysteine.	DL-ETHIONINE	120-133	peptidase D	Homo sapiens	49-58
16899234-11	2007	On the other hand, prolidase activity in their erythrocyte lysates was enhanced by D,L-ethionine, D-methionine and L-methionine.	DL-ETHIONINE	83-96	peptidase D	Homo sapiens	19-28
15469721-5	2004	Rats fed a control diet plus DL-ethionine showed a gradual decrease in liver DNA, RNA, total protein, and liver weight and enzyme activities of liver transaminases (GOT and GPT) and alkaline phosphatase over the 7-month study period.	DL-ETHIONINE	29-41	glutamic--pyruvic transaminase	Rattus norvegicus	173-176