PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
20864249-3	2011	We show that under serum starvation, overexpression of miR-290-295 miRNAs withhold ES cells from early differentiation, ensures their high proliferation rate and capacity for forming alkaline phosphate positive colonies.	alkaline phosphate	183-201	microRNA 290a	Mus musculus	55-62
31758855-2	2019	Case presentation We present an unusual patient with: (a) marked skeletal anomalies with secondary hyperparathyroidism; (b) serum intact parathyroid hormone level normalized by 7 weeks but abnormally elevated serum alkaline phosphate persisted; and (c) two mutations identified in the GNPTAB gene.	alkaline phosphate	215-233	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta	Homo sapiens	285-291
30463548-5	2018	RESULTS: Based on HDAC6 knockdown dental MSCs, our data suggest that HDAC6 knockdown significantly increases alkaline phosphate activity and mineralized nodules formation.	alkaline phosphate	109-127	histone deacetylase 6	Mus musculus	69-74
30001365-11	2018	Further, C/C genotype of IL-6 (G/C), T/T of CRP (C/T) and RR genotype of LEPR (Q/R) was associated with significantly higher BMI, fat mass (kg), % body fat, waist circumference, serum triglycerides, total cholesterol, alkaline phosphate, aspartate transaminase and fasting insulin levels in OSA and NAFLD subjects.	alkaline phosphate	218-236	interleukin 6	Homo sapiens	25-29
30001365-11	2018	Further, C/C genotype of IL-6 (G/C), T/T of CRP (C/T) and RR genotype of LEPR (Q/R) was associated with significantly higher BMI, fat mass (kg), % body fat, waist circumference, serum triglycerides, total cholesterol, alkaline phosphate, aspartate transaminase and fasting insulin levels in OSA and NAFLD subjects.	alkaline phosphate	218-236	leptin receptor	Homo sapiens	73-77
29476695-6	2018	Sgcb/Rag2/gammac-null muscles showed a significant reduction of alkaline phosphate-positive mesoangioblasts.	alkaline phosphate	64-82	sarcoglycan, beta (dystrophin-associated glycoprotein)	Mus musculus	0-4
29476695-6	2018	Sgcb/Rag2/gammac-null muscles showed a significant reduction of alkaline phosphate-positive mesoangioblasts.	alkaline phosphate	64-82	recombination activating gene 2	Mus musculus	5-9
29212557-7	2017	Increased osteogenic differentiation including alkaline phosphate activity and matrix mineralization was only observed in the LPS plus TNF-alpha preconditioned MSCs.	alkaline phosphate	47-65	tumor necrosis factor	Mus musculus	135-144
20223822-5	2010	Knocking down TNFRSF19 in hMSC-LRP5(T253) cells decreased Wnt3a-induced osteoblast differentiation marker alkaline phosphate activity and its overexpression in hMSC-LRP5(T244) cells increased alkaline phosphate activity.	alkaline phosphate	106-124	TNF receptor superfamily member 19	Homo sapiens	14-22
20223822-5	2010	Knocking down TNFRSF19 in hMSC-LRP5(T253) cells decreased Wnt3a-induced osteoblast differentiation marker alkaline phosphate activity and its overexpression in hMSC-LRP5(T244) cells increased alkaline phosphate activity.	alkaline phosphate	106-124	LDL receptor related protein 5	Homo sapiens	31-35
20223822-5	2010	Knocking down TNFRSF19 in hMSC-LRP5(T253) cells decreased Wnt3a-induced osteoblast differentiation marker alkaline phosphate activity and its overexpression in hMSC-LRP5(T244) cells increased alkaline phosphate activity.	alkaline phosphate	106-124	Wnt family member 3A	Homo sapiens	58-63
20223822-5	2010	Knocking down TNFRSF19 in hMSC-LRP5(T253) cells decreased Wnt3a-induced osteoblast differentiation marker alkaline phosphate activity and its overexpression in hMSC-LRP5(T244) cells increased alkaline phosphate activity.	alkaline phosphate	192-210	TNF receptor superfamily member 19	Homo sapiens	14-22
20223822-5	2010	Knocking down TNFRSF19 in hMSC-LRP5(T253) cells decreased Wnt3a-induced osteoblast differentiation marker alkaline phosphate activity and its overexpression in hMSC-LRP5(T244) cells increased alkaline phosphate activity.	alkaline phosphate	192-210	LDL receptor related protein 5	Homo sapiens	31-35
20223822-5	2010	Knocking down TNFRSF19 in hMSC-LRP5(T253) cells decreased Wnt3a-induced osteoblast differentiation marker alkaline phosphate activity and its overexpression in hMSC-LRP5(T244) cells increased alkaline phosphate activity.	alkaline phosphate	192-210	Wnt family member 3A	Homo sapiens	58-63
19944014-3	2009	Herein, we attempt to use an alkaline phosphate (AP)-fused form of single-chain variable fragment (scFv) for the simple identification of a hybridoma-derived, functional recombinant antibody.	alkaline phosphate	29-47	immunglobulin heavy chain variable region	Homo sapiens	99-103
1459694-2	1992	We examined the cytokines interleukin-1-beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) for their effects on osteoblastic proliferation and development and expression of alkaline phosphate and the osteoblast-specific protein osteocalcin in a mineralizing environment.	alkaline phosphate	183-201	interleukin 1 beta	Homo sapiens	26-44
19055838-2	2008	METHODS: P38 kinase activity was evaluated in a kinase assay by measuring the amount of phosphorylated substrate ATF2 using a phosphoATF2 (Thr71) specific primary antibody and an alkaline phosphate coupled secondary antibody and measuring the OD at 405 nm.	alkaline phosphate	179-197	mitogen-activated protein kinase 14	Homo sapiens	9-12
9610754-10	1998	The percentage increase of serum IGFBP-5 after GH therapy showed a positive correlation with the percentage increase of total alkaline phosphate activity (r = 0.347 p < 0.05).	alkaline phosphate	126-144	insulin like growth factor binding protein 5	Homo sapiens	33-40
9610754-10	1998	The percentage increase of serum IGFBP-5 after GH therapy showed a positive correlation with the percentage increase of total alkaline phosphate activity (r = 0.347 p < 0.05).	alkaline phosphate	126-144	growth hormone 1	Homo sapiens	47-49
12816724-7	2003	The different secreted alkaline phosphate activities among these 3 cell lines suggest that the expression of human IL-13Ra2 is regulated at the transcriptional level.	alkaline phosphate	23-41	interleukin 13 receptor subunit alpha 2	Homo sapiens	115-123
1459694-2	1992	We examined the cytokines interleukin-1-beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) for their effects on osteoblastic proliferation and development and expression of alkaline phosphate and the osteoblast-specific protein osteocalcin in a mineralizing environment.	alkaline phosphate	183-201	interleukin 1 beta	Homo sapiens	46-55
1459694-2	1992	We examined the cytokines interleukin-1-beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) for their effects on osteoblastic proliferation and development and expression of alkaline phosphate and the osteoblast-specific protein osteocalcin in a mineralizing environment.	alkaline phosphate	183-201	tumor necrosis factor	Homo sapiens	61-88
1459694-2	1992	We examined the cytokines interleukin-1-beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) for their effects on osteoblastic proliferation and development and expression of alkaline phosphate and the osteoblast-specific protein osteocalcin in a mineralizing environment.	alkaline phosphate	183-201	tumor necrosis factor	Homo sapiens	90-99
33746773-5	2021	Overexpression of ETS1 promoted expression of osteogenic markers, alkaline phosphate concentration, and calcareous accumulation in cells.	alkaline phosphate	66-84	E26 avian leukemia oncogene 1, 5' domain	Mus musculus	18-22
34449768-8	2021	In addition, Gly/Arg genotype of IRS1 gene was associated with significantly higher body mass index, fat mass, %body fat, triglycerides, cholesterol, alkaline phosphate, aspartate transaminase, fasting insulin and HOMA-IR levels in OSA and NAFLD subjects.	alkaline phosphate	150-168	insulin receptor substrate 1	Homo sapiens	33-37
34445348-4	2021	We herein demonstrated that PPARgamma was expressed by in vivo periodontal ligament tissue and its distribution pattern correlated with alkaline phosphate enzyme activity.	alkaline phosphate	136-154	peroxisome proliferator activated receptor gamma	Homo sapiens	28-37
2307501-2	1990	The study revealed that the activities of brush border sucrase, lactase and leucine aminopeptidase were stimulated only at high doses, viz 70 mg/kg (180 mumol/kg) body weight and above, whereas the activity of alkaline phosphate was depressed at comparatively low dose (17.5 mg/kg; 45 mumol/kg body weight).	alkaline phosphate	210-228	lactase	Rattus norvegicus	64-71