PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 30184753-1 2018 A novel magnetic nanocomposite based on magnetite nanoparticles-functionalized-graphene oxide and hexadecyltrimethyl ammonium bromide has been synthesized (MAGO-CTAB) by a facile route for efficient, fast and sensitive binding with Sunset Yellow (SY). 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 232-245 mago homolog B, exon junction complex subunit Homo sapiens 156-165 30274892-5 2019 According to Box-Behnken design based on desirability function (DF), the best experimental conditions was set as initial sunset yellow concentration 10 mgL-1, initial tartrazine concentration 8.5 mgL-1, adsorbent dosage 0.045 g and sonication time of 15 min. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 121-134 LLGL scribble cell polarity complex component 1 Homo sapiens 152-157 33979123-4 2021 Among promising candidates identified, several dyes (Congo red, direct violet 1, Evans blue) and novel druglike compounds (DRI-C23041, DRI-C91005) inhibited the interaction of hACE2 with the spike proteins of SARS-CoV-2 as well as SARS-CoV with low micromolar activity in our cell-free ELISA-type assays (IC50"s of 0.2-3.0 muM), whereas control compounds, such as sunset yellow FCF, chloroquine, and suramin, showed no activity. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 364-381 angiotensin converting enzyme 2 Homo sapiens 176-181 33979123-4 2021 Among promising candidates identified, several dyes (Congo red, direct violet 1, Evans blue) and novel druglike compounds (DRI-C23041, DRI-C91005) inhibited the interaction of hACE2 with the spike proteins of SARS-CoV-2 as well as SARS-CoV with low micromolar activity in our cell-free ELISA-type assays (IC50"s of 0.2-3.0 muM), whereas control compounds, such as sunset yellow FCF, chloroquine, and suramin, showed no activity. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 364-381 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 191-196 31449473-7 2019 The relative standard deviation (RSD) for 0.1 mg L-1 of Sunset Yellow was 2.6% (n = 10). 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 56-69 immunoglobulin kappa variable 1-16 Homo sapiens 49-52 31301288-0 2019 Synergistic inhibition of catalase activity by food colorants sunset yellow and curcumin: An experimental and MLSD simulation approach. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 62-75 catalase Homo sapiens 26-34 23993542-4 2013 The peak currents of sunset yellow and tartrazine increased linearly with their concentration in the ranges of 0.02-2.05 muM and 0.02-1.18 muM, respectively. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 21-34 latexin Homo sapiens 121-124 27589980-8 2016 Our method allowed us to give the first reported estimation of K24 for the lyotropic chromonic liquid crystal Sunset Yellow FCF: K 24 = 2.1 pN. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 110-123 keratin 24 Homo sapiens 63-66 30280050-0 2018 Sunset Yellow and Allura Red modulate Bcl2 and COX2 expression levels and confer oxidative stress-mediated renal and hepatic toxicity in male rats. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 0-13 BCL2, apoptosis regulator Rattus norvegicus 38-42 30280050-0 2018 Sunset Yellow and Allura Red modulate Bcl2 and COX2 expression levels and confer oxidative stress-mediated renal and hepatic toxicity in male rats. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 0-13 cytochrome c oxidase II, mitochondrial Rattus norvegicus 47-51 26398421-1 2015 An electrochemical sensor was prepared using Au nanoparticles and reduced graphene successfully decorated on the glassy carbon electrode (Au/RGO/GCE) through an electrochemical method which was applied to detect Sunset Yellow (SY). 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 212-225 aminomethyltransferase Homo sapiens 145-148 23993542-4 2013 The peak currents of sunset yellow and tartrazine increased linearly with their concentration in the ranges of 0.02-2.05 muM and 0.02-1.18 muM, respectively. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 21-34 latexin Homo sapiens 139-142 22562034-6 2012 Using this assay, the coal-derived food and cosmetic colourings--sunset yellow and tartrazine--were identified as novel human ERalpha activators, activating the human ER with an EC(50%) concentration of 220 and 160 nM, respectively. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 65-78 estrogen receptor 1 Homo sapiens 126-133 22342611-7 2012 The results also indicated that the oral administration of selenium ACE significantly reduced the genotoxic effects of sunset yellow, a result that may support the use of antioxidants as chemopreventive agents in many applications. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 119-132 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 68-71 22615687-4 2012 Lucifer Yellow injected into weakly fixed CA3pyr was detected in MF axons that contacted four injected CA3pyr, supporting gap junction-mediated coupling between those two types of principal cells. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 8-14 carbonic anhydrase 3 Rattus norvegicus 42-45 19551948-9 2008 In this work we demonstrate dosing of Lucifer Yellow CH, LY, a charged fluorescent dye, into individual a7r5 vascular smooth muscle cells with a DMB. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 46-52 RT1 class II, locus DMb Rattus norvegicus 145-148 18964996-1 1990 A study has been made of the polarographic (DC and DPP) behaviour of the food dyes Sunset Yellow and Tartrazine in acid and alkaline media and in the absence and presence of polyvinylpyrrolidone. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 83-96 dentin sialophosphoprotein Homo sapiens 51-54 34856315-6 2022 The developed sunset yellow sensor exhibited a high sensitivity of 4.16 muA muM-1 cm-2 and a nanomolar detection limit of 0.9 nM in the linear range 0.125-108.5 muM. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 14-27 PWWP domain containing 3A, DNA repair factor Homo sapiens 76-86 34973990-0 2022 The inhibitory effect of Sunset Yellow on thermally induced Human Serum Albumin aggregates: Possible role in naturopathy. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 25-38 albumin Homo sapiens 66-79 34973990-2 2022 Herein, we elaborated the anti amyloidogenic potential of Sunset Yellow (SY) dye against Human Serum Albumin (HSA) fibrillogenesis utilising different biophysical, computational and microscopic techniques. 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt 58-71 albumin Homo sapiens 95-108