PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 15226253-2 2004 For example, in short-day photoperiods, the Arabidopsis floral transition is strongly promoted by GA-mediated activation of the floral meristem-identity gene LEAFY. Gallium 98-100 floral meristem identity control protein LEAFY (LFY) Arabidopsis thaliana 158-163 14998543-1 2004 Gas-phase complexes of triply charged metal ions with peptides may be readily produced using electrospray ionization, including for small peptides such as bradykinin and peptides with no basic residues such as insulin chain A. Attachment without charge-reduction is demonstrated for all trications studied: La(3+), Al(3+), Ga(3+), Fe(3+), V(3+), and Cr(3+). Gallium 0-2 kininogen 1 Homo sapiens 155-165 15155128-5 2004 Gallium has unique mechanisms of action that include its binding to transferrin in the circulation and targeting transferrin receptors present on lymphoma cells. Gallium 0-7 transferrin Homo sapiens 68-79 15155128-5 2004 Gallium has unique mechanisms of action that include its binding to transferrin in the circulation and targeting transferrin receptors present on lymphoma cells. Gallium 0-7 transferrin Homo sapiens 113-124 14999769-2 2004 GA and related molecules act by inhibiting the chaperone function of the Hsp90 protein through competition for ATP binding. Gallium 0-2 heat shock protein 90 alpha family class A member 1 Homo sapiens 73-78 14999769-6 2004 We show that GA triggers a rapid and marked decrease in the kinase activity of the cyclin E/cdk2 complex coupled with a decline in both total and cdk2-associated cyclin E. In transient transfection experiments, inhibition of cyclin E expression by GA was correlated with inhibition of the transcriptional activity of the cyclin E gene promoter. Gallium 13-15 cyclin dependent kinase 2 Homo sapiens 92-96 14999769-6 2004 We show that GA triggers a rapid and marked decrease in the kinase activity of the cyclin E/cdk2 complex coupled with a decline in both total and cdk2-associated cyclin E. In transient transfection experiments, inhibition of cyclin E expression by GA was correlated with inhibition of the transcriptional activity of the cyclin E gene promoter. Gallium 13-15 cyclin dependent kinase 2 Homo sapiens 146-150 14999769-7 2004 Inhibition of cdk4 activity by GA was observed 3 hr after addition of the drug to late G(1) cells but not after a short (1 hr) exposure, as revealed by the phosphorylation of Rb on the Ser(780) residue. Gallium 31-33 cyclin dependent kinase 4 Homo sapiens 14-18 15050437-9 2004 These results are consistent with the conclusion that the two SOD1 mutants, by an unknown mechanism, promote the dispersion of the GA and the dysfunction of the secretory pathway. Gallium 131-133 superoxide dismutase [Cu-Zn] Cricetulus griseus 62-66 15104216-5 2004 RESULTS: Plasma fibrinogen was higher in AA homozygous participants (341 mg/dL) than in participants carrying the G allele: GA (290 mg/dL), GG (298 mg/dL) in the control group. Gallium 124-126 fibrinogen beta chain Homo sapiens 16-26 15104216-6 2004 Plasma fibrinogen was also higher in AA homozygous patients (353 mg/dL) than in cases carrying the G allele: GA (287 mg/dL), GG (302 mg/dL) in the ICVD group. Gallium 109-111 fibrinogen beta chain Homo sapiens 7-17 14871311-9 2004 These results suggest that DDF1 is involved in the regulation of GA biosynthesis and stress tolerance. Gallium 65-67 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 27-31 14756759-6 2004 In addition, a GA-deficient mutant (ga1-3) did not form an apical hook in the presence of the ethylene precursor 1-aminocyclopropane-1-carboxylate (ACC). Gallium 15-17 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 36-41 14963244-6 2004 Although the ability of pkl seedlings to express embryonic traits is strongly induced by inhibiting GA biosynthesis, it is only marginally responsive to abscisic acid and SPY (SPINDLY), factors that have previously been demonstrated to inhibit GA-dependent responses during germination. Gallium 100-102 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 24-27 14963244-8 2004 These observations indicate that PKL may mediate a subset of GA-dependent responses during shoot development. Gallium 61-63 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 33-36 14756759-9 2004 Furthermore, expression of GASA1, a GA-response gene, suggests that differential cell elongation in the apical hook might be a result of differential GA-sensitivity. Gallium 36-38 GAST1 protein homolog 1 Arabidopsis thaliana 27-32 14698421-3 2004 The MYCL1 repeat is actually a complex repeat, made up of approximately 14 GAAA tetranucleotides plus various other GA-rich repeats. Gallium 75-77 MYCL proto-oncogene, bHLH transcription factor Homo sapiens 4-9 15579097-3 2004 The abundance of transferrin receptors and the up-regulation of ribonucleotide reductase render tumor cells susceptible to the cytotoxicity of gallium. Gallium 143-150 transferrin Homo sapiens 17-28 15206110-3 2004 Even though its inability to shift between the trivalent and a divalent oxidation state precludes that gallium behaves as an iron analogue in every respect, it strongly interferes with cellular acquisition of iron from blood by competitive interaction with transferrin and transferrin receptor-mediated endocytosis. Gallium 103-110 transferrin Homo sapiens 257-268 15206110-3 2004 Even though its inability to shift between the trivalent and a divalent oxidation state precludes that gallium behaves as an iron analogue in every respect, it strongly interferes with cellular acquisition of iron from blood by competitive interaction with transferrin and transferrin receptor-mediated endocytosis. Gallium 103-110 transferrin Homo sapiens 273-284 15206110-6 2004 Both the abundance of transferrin receptors and upregulation of ribonucleotide reductase render tumors susceptible to gallium-induced cytotoxicity. Gallium 118-125 transferrin Homo sapiens 22-33 14644450-1 2003 The glycine-alanine (GA) repeat of the Epstein-Barr virus nuclear antigen-1 inhibits in cis ubiquitin-dependent proteolysis in mammalian cells through a yet unknown mechanism. Gallium 21-23 ubiquitin Saccharomyces cerevisiae S288C 92-101 14615596-5 2003 Second, ethylene delayed the GA-induced disappearance of the DELLA protein repressor of ga1-3 from root cell nuclei via a constitutive triple response-dependent signaling pathway. Gallium 29-31 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 88-93 14644623-6 2003 Our results revealed that low concentrations (1-10 microg/ml) of gallium promoted cells to enter the S phase of cell cycle and enhanced cellular release of tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma, both in vitro and in vivo. Gallium 65-72 interleukin 1 beta Homo sapiens 185-202 14644623-6 2003 Our results revealed that low concentrations (1-10 microg/ml) of gallium promoted cells to enter the S phase of cell cycle and enhanced cellular release of tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma, both in vitro and in vivo. Gallium 65-72 interferon gamma Homo sapiens 208-224 14644623-8 2003 Furthermore, gallium-induced cytokine release and apoptosis could be inhibited by iron-saturated transferrin (Tf-Fe). Gallium 13-20 transferrin Homo sapiens 97-108 14713199-4 2003 A mutant allele, gai, encodes a mutant protein (gai) that has altered properties, and confers a dominant, reduced GA-response, dwarf phenotype. Gallium 114-116 GRAS family transcription factor family protein Arabidopsis thaliana 17-20 14713199-4 2003 A mutant allele, gai, encodes a mutant protein (gai) that has altered properties, and confers a dominant, reduced GA-response, dwarf phenotype. Gallium 114-116 GRAS family transcription factor family protein Arabidopsis thaliana 48-51 12854969-8 2003 In addition, we observed weak binding to a GA-rich site within -110/-82 (Sp-C). Gallium 43-45 surfactant protein C Homo sapiens 73-77 12895122-6 2003 Aluminum and gallium compounds with three terminal ethynyl groups Al(C triplebond CPh)(3).NMe(3) (10) and Ga(C triplebond CPh)(3).NMe(3) (11) have been prepared by the reaction of AlH(3).NMe(3) or GaH(3).NMe(3) with three equivalents of phenylethyne. Gallium 13-20 carboxypeptidase E Homo sapiens 82-85 12971756-1 2003 The exchange of Fe(3+), Tb(3+), In(3+), Ga(3+), and Al(3+) between the C-terminal metal-binding site of the serum iron transport protein transferrin and the low-molecular-mass serum chelating agent citrate has been studied at pH 7.4 and 25 degrees C. The removal of Ga(3+), In(3+), and Al(3+) follows simple saturation kinetics with respect to the citrate concentration. Gallium 40-42 transferrin Homo sapiens 137-148 14569300-7 2003 Gallium was used instead of iron in the metal-binding studies, since it resulted in increased stability of recombinant transferrin binding protein B in the complex. Gallium 0-7 transferrin Homo sapiens 119-130 14569300-9 2003 Kinetic and equilibrium binding studies indicated that transferrin binds gallium more tightly in the presence of transferrin binding protein B. Gallium 73-80 transferrin Homo sapiens 55-66 14569300-9 2003 Kinetic and equilibrium binding studies indicated that transferrin binds gallium more tightly in the presence of transferrin binding protein B. Gallium 73-80 transferrin Homo sapiens 113-124 12791823-9 2003 These results imply that (67)Ga uptake by cells with wild-type HFE may differ from cells with the HFE C282Y mutation. Gallium 29-31 homeostatic iron regulator Homo sapiens 63-66 12940954-3 2003 Here, we present evidences that SOC1 also integrates signaling from the GA-dependent pathway, a major flowering pathway under non-inductive short days. Gallium 72-74 AGAMOUS-like 20 Arabidopsis thaliana 32-36 12940954-4 2003 Under short days, the flowering time of GA-biosynthetic and -signaling mutants was well correlated with the level of SOC1 expression; overexpression of SOC1 rescued the non-flowering phenotype of ga1-3, and the soc1 null mutant showed reduced sensitivity to GA for flowering. Gallium 40-42 AGAMOUS-like 20 Arabidopsis thaliana 152-156 12940954-4 2003 Under short days, the flowering time of GA-biosynthetic and -signaling mutants was well correlated with the level of SOC1 expression; overexpression of SOC1 rescued the non-flowering phenotype of ga1-3, and the soc1 null mutant showed reduced sensitivity to GA for flowering. Gallium 40-42 AGAMOUS-like 20 Arabidopsis thaliana 211-215 12791823-8 2003 CONCLUSION: Our studies suggest that expression of wild-type HFE in cells produces a decrease in (67)Ga uptake due to a reduction in available Tf binding sites for (67)Ga-Tf on the TfR. Gallium 101-103 homeostatic iron regulator Homo sapiens 61-64 12805613-4 2003 These genes encode the enzymes ent-copalyl diphosphate synthase (CPS) and ent-kaurene synthase, which catalyze the first two committed steps in GA biosynthesis. Gallium 144-146 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 31-63 12805613-4 2003 These genes encode the enzymes ent-copalyl diphosphate synthase (CPS) and ent-kaurene synthase, which catalyze the first two committed steps in GA biosynthesis. Gallium 144-146 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 65-68 12742022-3 2003 The kinetic fluorescence measurement revealed that aluminium, beryllium, and gallium ions, when complexed with the fluoride ion and ADP, induced a biphasic fluorescence change of pyrenyl GroEL, while scandium and vanadate ions did not induce any kinetically observed change in fluorescence. Gallium 77-84 heat shock protein family D (Hsp60) member 1 Homo sapiens 187-192 12724538-4 2003 The DELLA domain protein RGA (repressor of ga1-3) is a repressor of GA response that appears to undergo GA-stimulated protein degradation. Gallium 26-28 GRAS family transcription factor family protein Arabidopsis thaliana 30-48 12724538-8 2003 The predicted SLY1 amino acid sequence is highly conserved among plants, indicating a key role in GA response. Gallium 98-100 F-box family protein Arabidopsis thaliana 14-18 12610625-6 2003 We also show that auxin is necessary for GA-mediated control of root growth, and that attenuation of auxin transport or signalling delays the GA-induced disappearance of RGA from root cell nuclei. Gallium 142-144 GRAS family transcription factor family protein Arabidopsis thaliana 170-173 12457219-6 2003 Killing specific to GA-733 was assayed by C26-EpCAM-killing assay. Gallium 20-22 epithelial cell adhesion molecule Mus musculus 46-51 18238167-2 2003 The objective of our work is to improve the GA-based ARG matching procedures leading to a faster convergence rate and better quality mapping between a scene ARG and a set of given model ARGs. Gallium 44-46 serpin family A member 2 (gene/pseudogene) Homo sapiens 186-190 12509528-7 2003 Lines containing increased expression of AtGA2ox8 exhibited a GA dose-response curve for stem elongation similar to that of the biosynthetic mutant ga1-11. Gallium 43-45 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 148-154 12516212-1 2002 The mass transport of gallium adatoms in a confined gallium bilayer on GaN(0001) is studied with photoelectron spectromicroscopy with the goal to identify the diffusing species and their lateral distribution during directional surface electromigration and/or "random" thermal diffusion. Gallium 22-29 gigaxonin Homo sapiens 71-74 12536783-1 2002 Asymmetric Mukaiyama aldol reactions in aqueous media (water-ethanol = 9:1) were catalyzed by chiral gallium catalysts with semi-crown ligands to give aldol products with good yields, syn-diastereoselectivities and enantioselectivities. Gallium 101-108 synemin Homo sapiens 184-187 12420101-3 2002 The profile encompasses three criteria, a) reduced proliferative response to GA (as observed with a standard primary proliferation assay); b) strong in vitro activation of interferon-gamma-producing T cells at high concentrations of GA (as detected by interferon-gamma ELISPOT); and c) activation of interleukin-4-producing T cells over a wider range of concentrations of GA (as detected by interleukin-4 ELISPOT). Gallium 233-235 interferon gamma Homo sapiens 172-188 12420101-3 2002 The profile encompasses three criteria, a) reduced proliferative response to GA (as observed with a standard primary proliferation assay); b) strong in vitro activation of interferon-gamma-producing T cells at high concentrations of GA (as detected by interferon-gamma ELISPOT); and c) activation of interleukin-4-producing T cells over a wider range of concentrations of GA (as detected by interleukin-4 ELISPOT). Gallium 233-235 interferon gamma Homo sapiens 252-268 12516212-1 2002 The mass transport of gallium adatoms in a confined gallium bilayer on GaN(0001) is studied with photoelectron spectromicroscopy with the goal to identify the diffusing species and their lateral distribution during directional surface electromigration and/or "random" thermal diffusion. Gallium 52-59 gigaxonin Homo sapiens 71-74 12372247-10 2002 Furthermore, we provide evidence that one of the functions of the KNOX protein SHOOTMERISTEMLESS (STM) is to exclude transcription of the GA-biosynthesis gene AtGA20ox1 from the SAM. Gallium 138-140 KNOX/ELK homeobox transcription factor Arabidopsis thaliana 79-96 12372247-10 2002 Furthermore, we provide evidence that one of the functions of the KNOX protein SHOOTMERISTEMLESS (STM) is to exclude transcription of the GA-biosynthesis gene AtGA20ox1 from the SAM. Gallium 138-140 KNOX/ELK homeobox transcription factor Arabidopsis thaliana 98-101 12372247-10 2002 Furthermore, we provide evidence that one of the functions of the KNOX protein SHOOTMERISTEMLESS (STM) is to exclude transcription of the GA-biosynthesis gene AtGA20ox1 from the SAM. Gallium 138-140 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 159-168 12529982-2 2002 In the present study, we found that iron depletion was produced by the iron chelator deferoxamine mesylate, the free toxic metals gallium or indium, and the toxic metals gallium or indium bound to transferrin in the MCF-7 human breast cancer cell line, and this induced the condensation and fragmentation of chromatin, and the formation of DNA fragments characteristic of apoptosis. Gallium 170-177 transferrin Homo sapiens 197-208 12529982-4 2002 The apoptosis, caused by deferoxamine mesylate, and gallium or indium bound to transferrin in the MCF-7 cells, can be completely inhibited by excess ferric chloride or equimolar iron-loaded transferrin. Gallium 52-59 transferrin Homo sapiens 79-90 12529982-4 2002 The apoptosis, caused by deferoxamine mesylate, and gallium or indium bound to transferrin in the MCF-7 cells, can be completely inhibited by excess ferric chloride or equimolar iron-loaded transferrin. Gallium 52-59 transferrin Homo sapiens 190-201 11944910-5 2002 Deletion of the GA-rich segment significantly reduced the MARCKS promoter activity. Gallium 16-18 myristoylated alanine rich protein kinase C substrate Mus musculus 58-64 12420101-3 2002 The profile encompasses three criteria, a) reduced proliferative response to GA (as observed with a standard primary proliferation assay); b) strong in vitro activation of interferon-gamma-producing T cells at high concentrations of GA (as detected by interferon-gamma ELISPOT); and c) activation of interleukin-4-producing T cells over a wider range of concentrations of GA (as detected by interleukin-4 ELISPOT). Gallium 233-235 interferon gamma Homo sapiens 172-188 12420101-3 2002 The profile encompasses three criteria, a) reduced proliferative response to GA (as observed with a standard primary proliferation assay); b) strong in vitro activation of interferon-gamma-producing T cells at high concentrations of GA (as detected by interferon-gamma ELISPOT); and c) activation of interleukin-4-producing T cells over a wider range of concentrations of GA (as detected by interleukin-4 ELISPOT). Gallium 233-235 interferon gamma Homo sapiens 252-268 12121467-9 2002 The GA requirement was studied by using the GA biosynthesis inhibitor paclobutrazol, and genetically by generating double mutants with the GA-deficient mutant ga1-3. Gallium 4-6 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 159-164 12121467-11 2002 In a GA-deficient background, rdo1, rdo2 and rdo3, all show sensitivity to GA between that of ga1-3 and ga1-3 aba1. Gallium 5-7 transcript elongation factor IIS Arabidopsis thaliana 36-40 12121467-11 2002 In a GA-deficient background, rdo1, rdo2 and rdo3, all show sensitivity to GA between that of ga1-3 and ga1-3 aba1. Gallium 5-7 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 94-99 12121467-11 2002 In a GA-deficient background, rdo1, rdo2 and rdo3, all show sensitivity to GA between that of ga1-3 and ga1-3 aba1. Gallium 5-7 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 104-109 12121467-11 2002 In a GA-deficient background, rdo1, rdo2 and rdo3, all show sensitivity to GA between that of ga1-3 and ga1-3 aba1. Gallium 75-77 transcript elongation factor IIS Arabidopsis thaliana 36-40 12121467-11 2002 In a GA-deficient background, rdo1, rdo2 and rdo3, all show sensitivity to GA between that of ga1-3 and ga1-3 aba1. Gallium 75-77 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 94-99 12121467-11 2002 In a GA-deficient background, rdo1, rdo2 and rdo3, all show sensitivity to GA between that of ga1-3 and ga1-3 aba1. Gallium 75-77 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 104-109 12042984-9 2002 Results of a gallium scan with SPECT imaging may be an important method of confirming complete response, and should be incorporated into treatment programs, whether the treatment is standard CHOP or an investigational program. Gallium 13-20 DNA damage inducible transcript 3 Homo sapiens 191-195 12068105-7 2002 This result is consistent with the nuclear localization of other components of the GA response pathway and suggests that SPY"s role as a negative regulator of GA signaling involves interaction with other nuclear proteins and/or O-N-acetyl-glucosamine modification of these proteins. Gallium 83-85 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 121-124 12905631-4 2002 By in vitro kinase activity assay and Western blot, the effect of geldnamycin (GA) on heat induced JNK activity were evaluated. Gallium 79-81 mitogen-activated protein kinase 8 Homo sapiens 99-102 12905631-7 2002 With GA treatment, heat shock induced JNK activity was repressed, while the expression level of JNK or c-Jun was not obviously changed. Gallium 5-7 mitogen-activated protein kinase 8 Homo sapiens 38-41 11992468-7 2002 A downregulation of NMDA receptors, in particular of the NR2B subunit, is critically involved in this GA-induced effect, resulting in a reduced Ca(2+) increase and generation of reactive oxygen species after acute exposure to NMDA or 3-OH-GA. Gallium 102-104 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 57-61 11922726-1 2002 The nitrate form of the Group III transitional element gallium (GN) increases expression of specific structural components of the provisional wound matrix (i.e., collagen type I, fibronectin) in human dermal fibroblasts. Gallium 55-62 fibronectin 1 Homo sapiens 179-190 11864052-0 2002 Spin-lattice relaxation enhancement in liquid gallium confined within nanoporous matrices. Gallium 46-53 spindlin 1 Homo sapiens 0-4 11864052-1 2002 Nuclear spin relaxation for liquid gallium embedded into nanoporous matrices was found to accelerate remarkably compared to the bulk melt. Gallium 35-42 spindlin 1 Homo sapiens 8-12 11558562-8 2001 On the other hand, the inhibitory activity of hepatocyte medium on GA-induced cell death was completely abolished by anti-catalase antibody. Gallium 67-69 catalase Rattus norvegicus 122-130 11743113-6 2001 Causality was suggested by the finding that, with GA treatment, plants flowered in short days, AtMYB33 expression increased at the shoot apex, and the petioles elongated and grew erect. Gallium 50-52 myb domain protein 33 Arabidopsis thaliana 95-102 11717468-8 2001 Analysis of the mRNA levels of a GA biosynthetic gene, GA4, showed that the feedback control of GA biosynthesis in these transgenic plants was less responsive to GA than that in wild type. Gallium 33-35 gibberellin 3-oxidase 1 Arabidopsis thaliana 55-58 11717468-10 2001 Our results illustrate that the DELLA domain in RGA plays a regulatory role in GA-induced degradation of RGA. Gallium 49-51 GRAS family transcription factor family protein Arabidopsis thaliana 105-108 11785387-4 2001 If a combination of AZT and GA (1:1000) was used, p24 was not detected in the culture fluid by passage 20. Gallium 28-30 transmembrane p24 trafficking protein 2 Homo sapiens 50-53 11606552-3 2001 Previously, rga loss-of-function mutations were shown to partially suppress defects of the GA-deficient ga1-3 mutant. Gallium 91-93 GRAS family transcription factor family protein Arabidopsis thaliana 12-15 11606552-3 2001 Previously, rga loss-of-function mutations were shown to partially suppress defects of the GA-deficient ga1-3 mutant. Gallium 91-93 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 104-109 11606552-6 2001 Although gai-t6 alone has little effect, when combined with rga-24, they completely rescued the above defects of ga1-3 to wild-type or GA-overdose phenotype. Gallium 135-137 GRAS family transcription factor family protein Arabidopsis thaliana 60-63 11606552-8 2001 Additionally, rga-24 and rga-24/gai-t6 but not gai-t6 alone caused increased feedback inhibition of expression of a GA biosynthetic gene in both the ga1-3 and wild-type backgrounds. Gallium 116-118 GRAS family transcription factor family protein Arabidopsis thaliana 14-17 11606552-8 2001 Additionally, rga-24 and rga-24/gai-t6 but not gai-t6 alone caused increased feedback inhibition of expression of a GA biosynthetic gene in both the ga1-3 and wild-type backgrounds. Gallium 116-118 GRAS family transcription factor family protein Arabidopsis thaliana 25-28 11606552-8 2001 Additionally, rga-24 and rga-24/gai-t6 but not gai-t6 alone caused increased feedback inhibition of expression of a GA biosynthetic gene in both the ga1-3 and wild-type backgrounds. Gallium 116-118 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 149-154 11606552-9 2001 These results demonstrate that RGA and GAI have partially redundant functions in maintaining the repressive state of the GA-signaling pathway, but RGA plays a more dominant role than GAI. Gallium 32-34 GRAS family transcription factor family protein Arabidopsis thaliana 147-150 11552799-1 2001 The rigid tris- and bis(catecholamide) ligands H(6)A, H(4)B and H(4)C form tetrahedral clusters of the type M(4)L(4) and M(4)L(6) through self-assembly reactions with tri- and tetravalent metal ions such as Ga(III), Fe(III), Ti(IV) and Sn(IV). Gallium 207-209 H4 clustered histone 4 Homo sapiens 47-69 16200774-1 2001 OBJECTIVE: Using GA (geldanamycine), which specifically binding to HSP90, to induce the imbalance of HSP90/GR in function (low ratio) and analyzing the effect of low HSP90/GR ratio on T lymphocytes apoptosis induced by Dex from asthmatic patients. Gallium 17-19 heat shock protein 90 alpha family class A member 1 Homo sapiens 67-72 16200774-1 2001 OBJECTIVE: Using GA (geldanamycine), which specifically binding to HSP90, to induce the imbalance of HSP90/GR in function (low ratio) and analyzing the effect of low HSP90/GR ratio on T lymphocytes apoptosis induced by Dex from asthmatic patients. Gallium 17-19 heat shock protein 90 alpha family class A member 1 Homo sapiens 101-106 16200774-1 2001 OBJECTIVE: Using GA (geldanamycine), which specifically binding to HSP90, to induce the imbalance of HSP90/GR in function (low ratio) and analyzing the effect of low HSP90/GR ratio on T lymphocytes apoptosis induced by Dex from asthmatic patients. Gallium 17-19 heat shock protein 90 alpha family class A member 1 Homo sapiens 101-106 11678630-3 2001 Endothelium removal and treatment of GA with 17-octadecynoic acid (17-ODYA; suicide substrate inhibitor of CP450 4A enzymes) impaired oxygen-induced constriction of the vessels; treatment of endothelium-denuded GA with 17-ODYA eliminated responses to elevated PO2. Gallium 37-39 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 107-112 11558562-11 2001 These results show that GA-sensitive cells, including various tumor cells, produce only small amounts of catalase and secreted little enzyme into media, suggesting a lack of protective machinery against GA. Gallium 24-26 catalase Rattus norvegicus 105-113 11558562-12 2001 In contrast, GA-insensitive cells, including hepatocytes, produce large amounts of catalase and release it in medium, resulting in the development of insensitivity to GA. Gallium 13-15 catalase Rattus norvegicus 83-91 11669488-6 2001 Gallium was without significant effect on the channels and on SGLT1, NaPi-3, and rBAT, but inhibited BGT and OCT-2. Gallium 0-7 POU class 2 homeobox 2 Homo sapiens 109-114 11509602-9 2001 Finally, we observed that IL-4-mediated repression of IL-12 p40 promoter activity is critically dependent on an intact GA-12 sequence. Gallium 119-121 interleukin 4 Homo sapiens 26-30 11487315-0 2001 Preparation, characterization, and luminescence properties of gallium-metal face-to-face diporphyrins (M = H(2), GaL, Ru(CO)(OH), Co). Gallium 62-69 galanin and GMAP prepropeptide Homo sapiens 113-116 11548979-0 2001 Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS. Glatiromer acetate (GA) is an approved treatment for multiple sclerosis (MS). Gallium 136-138 myelin basic protein Homo sapiens 74-94 11548979-9 2001 Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL. Gallium 5-7 interleukin 5 Homo sapiens 92-96 11548979-9 2001 Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL. Gallium 5-7 myelin basic protein Homo sapiens 112-115 11548979-9 2001 Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL. Gallium 5-7 myelin basic protein Homo sapiens 139-142 11455201-4 2001 Treatment of GA with 17-octadecynoic acid (17-ODYA) alone to inhibit CP450 4A enzymes significantly reduced hypoxic dilation from control levels. Gallium 13-15 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 69-74 11449051-3 2001 However, expression of the GA biosynthetic gene GA4 was reduced 26% by the rga mutation, suggesting that partial derepression of the GA response pathway by rga resulted in the feedback inhibition of GA4 expression. Gallium 27-29 gibberellin 3-oxidase 1 Arabidopsis thaliana 48-51 11457902-4 2001 Treatment of the mutant with GA resulted in an accumulation of the tgas118 mRNA within hours in leaf and bud tissues. Gallium 29-31 gamma-thionin Solanum lycopersicum 67-74 33873372-8 2001 Enzymes that metabolize reactive oxygen species are also present in aleurone cells, but ascorbate peroxidase, catalase and superoxide dismutase become less abundant after treatment with GA; activity of these enzymes increases or remains unchanged in ABA-treated cells. Gallium 186-188 catalase Homo sapiens 110-118 11449051-3 2001 However, expression of the GA biosynthetic gene GA4 was reduced 26% by the rga mutation, suggesting that partial derepression of the GA response pathway by rga resulted in the feedback inhibition of GA4 expression. Gallium 27-29 GRAS family transcription factor family protein Arabidopsis thaliana 75-78 11449051-3 2001 However, expression of the GA biosynthetic gene GA4 was reduced 26% by the rga mutation, suggesting that partial derepression of the GA response pathway by rga resulted in the feedback inhibition of GA4 expression. Gallium 27-29 GRAS family transcription factor family protein Arabidopsis thaliana 156-159 11449051-3 2001 However, expression of the GA biosynthetic gene GA4 was reduced 26% by the rga mutation, suggesting that partial derepression of the GA response pathway by rga resulted in the feedback inhibition of GA4 expression. Gallium 27-29 gibberellin 3-oxidase 1 Arabidopsis thaliana 199-202 29712210-0 2001 Stable, Monomeric Imides of Aluminum and Gallium: Synthesis and Characterization of [{HC(MeCDippN)2 }MN-2,6-Trip2 C6 H3 ] (M=Al or Ga; Dipp=2,6-iPr2 C6 H3 ; Trip=2,4,6-iPr3 C6 H2 ). Gallium 41-43 mediator complex subunit 1 Homo sapiens 108-113 11457967-4 2001 To test the hypothesis that SPY acts specifically as a negatively acting component of GA signal transduction, spy mutants and plants containing a 35S:SPY construct have been examined. Gallium 86-88 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 28-31 11457975-8 2001 Expression of the TPR domain in a wild-type background produces phenotypes similar to those caused by loss-of-function spy mutants including resistance to GA biosynthesis inhibitors, short hypocotyl length, and early flowering. Gallium 155-157 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 119-122 11375697-3 2001 The iodide derivatives Dipp(2)nacnacMI(2) (M = Al (4), Ga (6), In (9)), which are useful for reduction to afford M(I) species, were made by a variety of routes. Gallium 55-57 nudix hydrolase 3 Homo sapiens 23-27 11375697-4 2001 Thus, 4 was obtained by treatment of the previously reported Dipp(2)nacnacAlMe(2) with I(2), whereas the gallium analogue 6 was obtained as a product of the reaction of "GaI" with Dipp(2)nacnacLi.Et(2)O, and 9 was obtained by direct reaction of InI(3) and the lithium salt. Gallium 105-112 nudix hydrolase 3 Homo sapiens 180-184 11375697-5 2001 The methyl derivatives Dipp(2)nacnacMMe(2) (M = Ga (7), In (10)), which are analogous to the previously reported Dipp(2)nacnacAlMe(2), were synthesized by the reaction of GaMe(3) with Dipp(2)nacnacH (1) or by reaction of the indium chloride derivative 8 with 2 equiv of MeMgBr in diethyl ether. Gallium 48-50 nudix hydrolase 3 Homo sapiens 23-27 11375697-5 2001 The methyl derivatives Dipp(2)nacnacMMe(2) (M = Ga (7), In (10)), which are analogous to the previously reported Dipp(2)nacnacAlMe(2), were synthesized by the reaction of GaMe(3) with Dipp(2)nacnacH (1) or by reaction of the indium chloride derivative 8 with 2 equiv of MeMgBr in diethyl ether. Gallium 48-50 nudix hydrolase 3 Homo sapiens 113-117 11375697-5 2001 The methyl derivatives Dipp(2)nacnacMMe(2) (M = Ga (7), In (10)), which are analogous to the previously reported Dipp(2)nacnacAlMe(2), were synthesized by the reaction of GaMe(3) with Dipp(2)nacnacH (1) or by reaction of the indium chloride derivative 8 with 2 equiv of MeMgBr in diethyl ether. Gallium 48-50 nudix hydrolase 3 Homo sapiens 113-117 11325843-0 2001 Immunoscintigraphy with positron emission tomography: gallium-68 chelate imaging of breast cancer pretargeted with bispecific anti-MUC1/anti-Ga chelate antibodies. Gallium 54-61 mucin 1, cell surface associated Homo sapiens 131-135 11737781-4 2001 Because another GA biosynthetic gene, AtKO1, coding for ent-kaurene oxidase, exhibited a similar cell-specific expression pattern, we predicted that the synthesis of bioactive GAs from ent-kaurene oxidation occurs in the same cell types during seed germination. Gallium 16-18 GA requiring 3 Arabidopsis thaliana 38-43 11737781-4 2001 Because another GA biosynthetic gene, AtKO1, coding for ent-kaurene oxidase, exhibited a similar cell-specific expression pattern, we predicted that the synthesis of bioactive GAs from ent-kaurene oxidation occurs in the same cell types during seed germination. Gallium 16-18 GA requiring 3 Arabidopsis thaliana 56-75 11737781-7 2001 When the AtCPS1 cDNA was expressed only in the cortex and endodermis of non-germinating ga1-3 seeds (deficient in AtCPS1) using the AtGA3ox2 promoter, germination was not as resistant to a GA biosynthesis inhibitor as expression in the provasculature. Gallium 134-136 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 9-15 11300841-6 2001 The closely spaced Sc1 chains in the parent Mn(5)Si(3) type transform to zigzag chains in concert with displacements of the uniformly spaced gallium atoms to form dimers within distorted confacial square antiprisms of Sc. Gallium 141-148 transcription factor 19 Homo sapiens 19-22 11351079-5 2001 The amounts and activities of ROS scavenging enzymes, including catalase (CAT), ascorbate peroxidase, and superoxide dismutase are strongly down-regulated in aleurone layers treated with GA. Gallium 187-189 prx7 Hordeum vulgare 90-100 11335103-0 2001 Iron and gallium increase iron uptake from transferrin by human melanoma cells: further examination of the ferric ammonium citrate-activated iron uptake process. Gallium 9-16 transferrin Homo sapiens 43-54 29712210-1 2001 A short Ga-N bond with double-bond character is displayed by the first monomeric imide of gallium, which was obtained by the reaction of [{HC(MeCDippN)2 }M:] (Dipp=2,6-iPr2 C6 H3 , M=Ga; see picture) with N3 -2,6-Trip2 C6 H3 (Trip=2,4,6-iPr3 C6 H2 ). Gallium 90-97 mediator complex subunit 1 Homo sapiens 213-218 11179048-4 2001 Treatment of GA with 17-octadecynoic acid (17-ODYA; inhibitor of CP450 4A enzymes) did not alter myogenic activation in NT rats, but impaired this response in HT animals. Gallium 13-15 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 65-70 11238378-2 2001 In this system, steroid treatment strictly induced NTH15 function and immediately suppressed the expression of a gibberellin (GA) biosynthetic gene encoding GA 20-oxidase (Ntc12) and also resulted in a decrease in bioactive GA levels. Gallium 126-128 gibberellin 20 oxidase 1-like Nicotiana tabacum 172-177 11238378-8 2001 The suppression of NTH15 within cells at the flanks of the SAM permits GA biosynthesis, which promotes organized cell proliferation and consequently induces the determination of cell fate. Gallium 71-73 homeobox protein knotted-1-like LET6 Nicotiana tabacum 19-24 11170549-3 2001 In addition, PH is formed from the reactions with Ga and In, with HMPH2 being its most likely precursor. Gallium 50-52 hematopoietically expressed homeobox Homo sapiens 66-70 11121490-5 2000 The CHOP ERSE is a novel variant of the ERSE as it contains two different functional domains, and a GA- instead of GC-rich intervening sequence. Gallium 100-102 DNA damage inducible transcript 3 Homo sapiens 4-8 11191281-9 2000 GA-positive patients instead had HLA DRB1*13 in 37.5% as compared to 8.6% in GA-negative (OR 6.4, etiologic fraction 0.32). Gallium 0-2 major histocompatibility complex, class II, DR beta 1 Homo sapiens 33-41 10829024-7 2000 These results suggest that the conserved GA-rich sequence of the elastin 3"-UTR is an important element in the regulation of stability of the elastin mRNA. Gallium 41-43 elastin Gallus gallus 65-72 10982849-2 2000 Previous studies have shown that a GA element near their transcriptional start sites is important for basal and cell-specific activities of the CLC-K1 and CLC-K2 gene promoters. Gallium 35-37 chloride voltage-gated channel Ka Homo sapiens 144-150 10982849-2 2000 Previous studies have shown that a GA element near their transcriptional start sites is important for basal and cell-specific activities of the CLC-K1 and CLC-K2 gene promoters. Gallium 35-37 chloride voltage-gated channel Kb Homo sapiens 155-161 11069843-7 2000 The patients positive for gallium-67 ((67)Ga) scan had significantly elevated serum IL-18 levels as compared with those of the negative patients. Gallium 26-33 interleukin 18 Homo sapiens 84-89 10978008-0 2000 Observation of "Ghost" islands and surfactant effect of surface gallium atoms during GaN growth by molecular beam epitaxy We observe "ghost" islands formed on terraces during homoepitaxial nucleation of GaN. Gallium 64-71 gigaxonin Homo sapiens 85-88 10978008-0 2000 Observation of "Ghost" islands and surfactant effect of surface gallium atoms during GaN growth by molecular beam epitaxy We observe "ghost" islands formed on terraces during homoepitaxial nucleation of GaN. Gallium 64-71 gigaxonin Homo sapiens 203-206 10960063-8 2000 In addition the ability of GA to block NO release and reduce oedema formation suggests a therapeutic rationale for specific inhibitors of Hsp90 as potential anti-inflammatory drugs. Gallium 27-29 heat shock protein, 3 Mus musculus 138-143 10829024-7 2000 These results suggest that the conserved GA-rich sequence of the elastin 3"-UTR is an important element in the regulation of stability of the elastin mRNA. Gallium 41-43 elastin Gallus gallus 142-149 10727770-2 2000 Gallium has also been shown to inhibit the production of inflammatory cytokines, such as IL-1beta, produced by macrophage-like cells in vitro. Gallium 0-7 interleukin-1 beta Oryctolagus cuniculus 89-97 10982455-4 2000 We show that levels of StGA20ox1 transcript are elevated in transgenic antisense plants that have reduced levels of phytochrome B (PHYB) compared with wild-type plants, implicating PHYB in the control of GA biosynthesis. Gallium 25-27 phytochrome B Solanum tuberosum 116-129 10982455-4 2000 We show that levels of StGA20ox1 transcript are elevated in transgenic antisense plants that have reduced levels of phytochrome B (PHYB) compared with wild-type plants, implicating PHYB in the control of GA biosynthesis. Gallium 25-27 phytochrome B Solanum tuberosum 131-135 10982455-4 2000 We show that levels of StGA20ox1 transcript are elevated in transgenic antisense plants that have reduced levels of phytochrome B (PHYB) compared with wild-type plants, implicating PHYB in the control of GA biosynthesis. Gallium 25-27 phytochrome B Solanum tuberosum 181-185 10801474-0 2000 Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo. Gallium 6-13 ATP binding cassette subfamily B member 1 Homo sapiens 44-48 10801474-0 2000 Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo. Gallium 6-13 ATP binding cassette subfamily B member 1 Homo sapiens 49-63 10801474-0 2000 Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo. Gallium 6-13 ATP binding cassette subfamily B member 1 Homo sapiens 106-120 10720473-4 2000 The induction of MCP-1 by GA was dose-dependent. Gallium 26-28 C-C motif chemokine ligand 2 Homo sapiens 17-22 10720473-5 2000 The MCP-1 mRNA expression by GA was completely inhibited by PD98059 and genistein that inhibit mitogen activated protein (MAP) kinase kinase and tyrosine kinase, respectively. Gallium 29-31 C-C motif chemokine ligand 2 Homo sapiens 4-9 10720473-6 2000 N-Acetylcysteine, a potent antioxidant, also suppressed the GA-induced MCP-1 expression. Gallium 60-62 C-C motif chemokine ligand 2 Homo sapiens 71-76 10720473-9 2000 GA-induced MCP-1 expression may be one of the mechanisms by which the diabetic patients suffer from accelerated atherosclerosis. Gallium 0-2 C-C motif chemokine ligand 2 Homo sapiens 11-16 10712532-6 2000 Stem elongation of transformed plants was severely inhibited, and normal growth could not be recovered by the application of GA. Our results indicate that Os-GRF1 belongs to a novel class of plant proteins and may play a regulatory role in GA-induced stem elongation. Gallium 125-127 growth-regulating factor 1 Arabidopsis thaliana 158-162 11017499-0 2000 Bistability in scanning tunneling spectroscopy of Ga-terminated Si(111) Bistable electron transport, a phenomenon usually associated with double-barrier structures, has been observed with a conventional STM junction formed between a metal tip and a Ga-terminated Si(111) surface at 77 K. Large hysteresis loops appear in the current-voltage characteristics when electrons are injected from the tip to the surface. Gallium 50-52 sulfotransferase family 1A member 3 Homo sapiens 203-206 11017499-0 2000 Bistability in scanning tunneling spectroscopy of Ga-terminated Si(111) Bistable electron transport, a phenomenon usually associated with double-barrier structures, has been observed with a conventional STM junction formed between a metal tip and a Ga-terminated Si(111) surface at 77 K. Large hysteresis loops appear in the current-voltage characteristics when electrons are injected from the tip to the surface. Gallium 249-251 sulfotransferase family 1A member 3 Homo sapiens 203-206 11130333-0 2000 Correlation of flow cytometric parameters and transferrin receptors with gallium-67 scintigraphic images in lymphoma patients. Gallium 73-80 transferrin Homo sapiens 46-57 11130333-1 2000 The purpose of this study was to determine the correlation of flow cytometric parameters and transferrin receptors with gallium-67 scintigraphic imaging results in Hodgkin"s and non-Hodgkin"s lymphoma patients. Gallium 120-127 transferrin Homo sapiens 93-104 11130333-5 2000 A strong relationship was observed between flow cytometry and transferrin receptor expression with gallium-67 tumour scintigraphy [P = 0.005, r = 0.054 and P = 0.038, r = 0.54 (Spearman test), respectively]. Gallium 99-106 transferrin Homo sapiens 62-73 10984896-0 2000 Diffuse bone increase uptake of gallium-67 related to cyclophosphamide and recombinant human granulocyte-colony stimulating factor (rHuG-CSF) administration. Gallium 32-39 colony stimulating factor 3 Homo sapiens 93-130 10794130-6 2000 We conclude that GA and 3-OH-GA act as excitotoxic organic acids (EOA) specifically through NR1/NR2B and that the extent of induced neurotoxicity is dependent on NR1/NR2B expression during maturation. Gallium 17-19 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 92-95 10794130-6 2000 We conclude that GA and 3-OH-GA act as excitotoxic organic acids (EOA) specifically through NR1/NR2B and that the extent of induced neurotoxicity is dependent on NR1/NR2B expression during maturation. Gallium 17-19 glutamate receptor, ionotropic, NMDA2B (epsilon 2) Mus musculus 96-100 10794130-6 2000 We conclude that GA and 3-OH-GA act as excitotoxic organic acids (EOA) specifically through NR1/NR2B and that the extent of induced neurotoxicity is dependent on NR1/NR2B expression during maturation. Gallium 17-19 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 162-165 10794130-6 2000 We conclude that GA and 3-OH-GA act as excitotoxic organic acids (EOA) specifically through NR1/NR2B and that the extent of induced neurotoxicity is dependent on NR1/NR2B expression during maturation. Gallium 17-19 glutamate receptor, ionotropic, NMDA2B (epsilon 2) Mus musculus 166-170 10654148-0 2000 The value of gallium-67 and thallium-201 whole-body and single-photon emission tomography images in dialysis-related beta 2-microglobulin amyloid. Gallium 13-20 beta-2-microglobulin Homo sapiens 117-137 10654148-1 2000 The aim of this study was to investigate the value of gallium-67 and thallium-201 whole-body and single-photon emission tomography (SPET) images in long-term dialysis patients in whom dialysis-related beta 2-microglobulin amyloid (beta 2-MA) was clinically suspected. Gallium 54-61 beta-2-microglobulin Homo sapiens 201-221 10430418-2 1999 BACKGROUND: GA is caused by inherited deficiency of ornithine-delta-aminotransferase activity. Gallium 12-14 ornithine aminotransferase Homo sapiens 52-84 14516612-5 1999 Various opportunistic infections also manifest with increased F18-FDG uptake.CONCLUSION: Total-body imaging can be done with F18-FDG with better resolution and a shorter procedure time compared to imaging with Gallium-67 (Ga-67). Gallium 210-217 mastermind like domain containing 1 Homo sapiens 62-65 11671166-5 1999 The metal cations are bound by three phenolic oxygens and three carbonyl oxygens in a ligand structure analogous to that of salicylamide. The ferric and gallium complexes of macrobicyclic TRENSAM are essentially isosteric and crystallize in the monoclinic space group P2(1)/n, with Z = 4. Gallium 154-161 cyclin dependent kinase inhibitor 1A Homo sapiens 269-274 10550633-5 1999 Hypocotyl cells of the GA-deficient mutant ga1-11 grown in the dark did not elongate and showed a greatly reduced endoreduplication. Gallium 23-25 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 43-49 10519143-7 1999 The data support our conclusion that stimulation of Ga,Cl by ATP is mediated by activation of the cAMP pathway and involves a CFTR-homologous protein. Gallium 52-54 CF transmembrane conductance regulator Homo sapiens 126-130 10205907-6 1999 GA analysis of the vegetative rosettes showed a two- to threefold increase in the level of GA4, indicating that GA 20-oxidase normally limits bioactive GA levels. Gallium 0-2 gibberellin 3-oxidase 1 Arabidopsis thaliana 91-94 9772210-7 1998 In cells treated with gallium-citrate/transferrin mixtures, 30 to 35% of the gallium in the cytosol was bound to protein, at least 35 being loosely bound; the main gallium-associated protein was probably intracellular transferrin. Gallium 22-29 transferrin Homo sapiens 218-229 10368174-3 1999 In agreement with this observation, the level of active GAs was elevated in shi plants, which is the result expected when feedback control of GA biosynthesis is reduced. Gallium 56-58 Lateral root primordium (LRP) protein-like protein Arabidopsis thaliana 76-79 9893925-5 1998 GA 1 nmol/1-10 mumol/l inhibited IL-1 production, and 100 nmol/l-10 mumol/l decreased TNF-alpha and NO production in dose-dependent manner. Gallium 0-2 interleukin 1 complex Mus musculus 33-37 9874508-6 1998 Using flow cytometry analysis, we reported the expression of transferrin-receptor (TfR) in each lymphoid cell line, and found a positive correlation between TfR density and the Ga-67 uptake (r = 0.99) in lymphoid cells. Gallium 177-179 transferrin receptor Homo sapiens 157-160 9874508-7 1998 The anti-TfR monoclonal antibody (MoAb) blocked significantly the Ga-67 uptake in all lymphoid cell lines indicating the Ga-67 uptake as a TfR-dependent mechanism. Gallium 66-68 transferrin receptor Homo sapiens 9-12 9874508-7 1998 The anti-TfR monoclonal antibody (MoAb) blocked significantly the Ga-67 uptake in all lymphoid cell lines indicating the Ga-67 uptake as a TfR-dependent mechanism. Gallium 121-123 transferrin receptor Homo sapiens 9-12 9874508-7 1998 The anti-TfR monoclonal antibody (MoAb) blocked significantly the Ga-67 uptake in all lymphoid cell lines indicating the Ga-67 uptake as a TfR-dependent mechanism. Gallium 121-123 transferrin receptor Homo sapiens 139-142 9874508-10 1998 To conclude, we have shown that the Ga-67 uptake is TfR-dependent in lymphoid cells. Gallium 36-38 transferrin receptor Homo sapiens 52-55 10344194-6 1999 In the leaf of the gib-1 mutant we demonstrated GA-enhanced histone leH1 and leH2B expression which was not observed in the wild type. Gallium 48-50 histone H1 Solanum lycopersicum 68-72 9952473-3 1999 We report the isolation of three potato cDNA clones (StGA20ox1-3) encoding GA 20-oxidase, a key regulatory enzyme in the GA-biosynthetic pathway. Gallium 55-57 gibberellin 20 oxidase 1-D Solanum tuberosum 75-88 10048953-0 1999 Changing biodistribution of gallium during G-CSF treatment in non- Hodgkin"s disease. Gallium 28-35 colony stimulating factor 3 Homo sapiens 43-48 9935072-0 1999 Photodegraded nifedipine promotes transferrin-independent gallium uptake by cultured tumor cells. Gallium 58-65 transferrin Homo sapiens 34-45 11670831-6 1998 The addition of AlCl(3) or GaCl(3) to the macrocyclic ligand precursor syn-Li(2)(dioxane)[P(2)N(2)] in toluene at 25 degrees C yields the five-coordinate complexes syn-MCl[P(2)N(2)] (M = Al (3), Ga (4)). Gallium 27-29 synemin Homo sapiens 71-74 11670831-11 1998 Barriers to pyramidal inversion (DeltaG()) were calculated to be 29.1 and 30.1 kcal mol(-)(1) for the aluminum and gallium complexes, respectively; these barriers are approximately 2-3 kcal mol(-)(1) lower than that determined for the metal-free, protonated compounds anti- and syn-H(2)[P(2)N(2)]. Gallium 115-122 synemin Homo sapiens 278-281 9772210-7 1998 In cells treated with gallium-citrate/transferrin mixtures, 30 to 35% of the gallium in the cytosol was bound to protein, at least 35 being loosely bound; the main gallium-associated protein was probably intracellular transferrin. Gallium 77-84 transferrin Homo sapiens 38-49 9772210-7 1998 In cells treated with gallium-citrate/transferrin mixtures, 30 to 35% of the gallium in the cytosol was bound to protein, at least 35 being loosely bound; the main gallium-associated protein was probably intracellular transferrin. Gallium 77-84 transferrin Homo sapiens 38-49 9708518-0 1998 Uptake of gallium-67 in transfected cells and tumors absent or enriched in the transferrin receptor. Gallium 10-17 transferrin receptor Homo sapiens 79-99 9701576-5 1998 Comparison of several different GA structures showed that GAs active in promoting hypocotyl elongation were also active in regulating GA4 transcript abundance, suggesting that similar GA:receptor and subsequent signal transduction processes control these two responses. Gallium 32-34 gibberellin 3-oxidase 1 Arabidopsis thaliana 134-137 9701576-7 1998 We also show that GA-mediated control of GA4 transcript abundance is disrupted in the GA-response mutants gai and spy-5. Gallium 18-20 gibberellin 3-oxidase 1 Arabidopsis thaliana 41-44 9616166-0 1998 Transferrin receptor-dependent and -independent iron transport in gallium-resistant human lymphoid leukemic cells. Gallium 66-73 transferrin Homo sapiens 0-11 9750350-2 1998 Quantitative analysis of intermediates in the GA biosynthetic pathway revealed that the step from GA19 to GA20 was blocked in transgenic tobacco plants overexpressing NTH15. Gallium 46-48 homeobox protein knotted-1-like LET6 Nicotiana tabacum 167-172 9747465-7 1998 In the accompanying article we report hATPA/GA-mediated resistance of human CD34+ haemopoietic progenitors to combined O6-beG/O6-alkylating agent toxicity. Gallium 44-46 CD34 molecule Homo sapiens 76-80 9604012-6 1998 Furthermore, incubation of GA-LDL with these macrophages and Chinese hamster ovary cells overexpressing the macrophage scavenger receptor (MSR), but not with peritoneal macrophages from MSR-knockout mice, led to the intracellular accumulation of cholesteryl esters (CE). Gallium 27-29 macrophage scavenger receptor 1 Mus musculus 139-142 9545353-5 1998 In the murine gene, a conserved GATA element bound to GATA-2 and functioned as a positive regulatory element, whereas a conserved Ets element bound to GA-binding protein and functioned as a negative regulatory element. Gallium 32-34 GATA binding protein 2 Mus musculus 54-60 9625690-1 1998 Using the GA-deficient mutant ga1-3, the GA-response mutant spy-5, and uniconazol (a GA-biosynthesis inhibitor), we show that the GA level response correlates positively with both trichome number and trichome branch number. Gallium 11-13 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 31-36 9625690-1 1998 Using the GA-deficient mutant ga1-3, the GA-response mutant spy-5, and uniconazol (a GA-biosynthesis inhibitor), we show that the GA level response correlates positively with both trichome number and trichome branch number. Gallium 42-44 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 31-36 9625690-1 1998 Using the GA-deficient mutant ga1-3, the GA-response mutant spy-5, and uniconazol (a GA-biosynthesis inhibitor), we show that the GA level response correlates positively with both trichome number and trichome branch number. Gallium 42-44 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 31-36 9625690-1 1998 Using the GA-deficient mutant ga1-3, the GA-response mutant spy-5, and uniconazol (a GA-biosynthesis inhibitor), we show that the GA level response correlates positively with both trichome number and trichome branch number. Gallium 131-133 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 31-36 9625690-6 1998 The activity of a beta-glucuronidase reporter gene driven by the GL1 promoter was decreased in the wild type grown on uniconazol and showed a clear GA-dependent activation in ga1-3. Finally, quantification of GL1 transcript levels by reverse transcriptase-polymerase chain reaction demonstrated that relative to wild type, ga1-3 plants contained less transcript. Gallium 149-151 myb domain protein 0 Arabidopsis thaliana 66-69 9625690-6 1998 The activity of a beta-glucuronidase reporter gene driven by the GL1 promoter was decreased in the wild type grown on uniconazol and showed a clear GA-dependent activation in ga1-3. Finally, quantification of GL1 transcript levels by reverse transcriptase-polymerase chain reaction demonstrated that relative to wild type, ga1-3 plants contained less transcript. Gallium 149-151 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 176-181 9673397-0 1998 Gallium-pyridoxal isonicotinoyl hydrazone (Ga-PIH), a novel cytotoxic gallium complex. Gallium 70-77 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 46-49 9673397-2 1998 The anti-proliferative activity of gallium-pyridoxal isonicotinoyl hydrazone (Ga-PIH), a novel gallium complex was compared with that of gallium nitrate, a known anti-tumor agent. Gallium 35-42 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 81-84 9673397-3 1998 At 50 microM, Ga-PIH inhibited CCRF-CEM cell growth by 45% compared to < 10% inhibition with gallium nitrate or PIH. Gallium 14-16 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 17-20 9630424-5 1998 Raised citrate markedly enhanced aluminum and gallium uptake into renal cortex and bone; in contrast with gallium-transferrin, citrate increased uptake of 67Ga into renal cortex and bone by 8- and 14-fold respectively. Gallium 106-113 transferrin Rattus norvegicus 114-125 9520278-12 1998 In a GA-deficient background (ga1-3), GUS activity in the vegetative meristem was detected only in the presence of supplied GA. Gallium 5-7 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 30-35 9520278-12 1998 In a GA-deficient background (ga1-3), GUS activity in the vegetative meristem was detected only in the presence of supplied GA. Gallium 124-126 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 30-35 9520278-13 1998 In root and flower meristems, basal GUS activity was slightly enhanced by exogenous GA. Interestingly, GA strongly inhibit GUS activity in expanding cotyledons and leaves in ga1-3 mutants supplied with exogenous GAs, as well as in the wild type. Gallium 84-86 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 174-179 9520278-14 1998 The GA-dependent meristem-specific expression pattern suggests that the GASA4 protein plays a role in dividing cells rather than in elongating cells. Gallium 4-6 GAST1 protein homolog 4 Arabidopsis thaliana 72-77 9504581-2 1998 DESIGN: Measure the pulmonary transcapillary escape rate with gallium (Ga)-68 labeled transferrin (PTCER(tf)) and positron emission tomography (PET) imaging and compare the results to similar measurements obtained with C-11 labeled methylalbumin (PTCER(alb)). Gallium 62-69 inhibitor of carbonic anhydrase Canis lupus familiaris 86-97 9504581-2 1998 DESIGN: Measure the pulmonary transcapillary escape rate with gallium (Ga)-68 labeled transferrin (PTCER(tf)) and positron emission tomography (PET) imaging and compare the results to similar measurements obtained with C-11 labeled methylalbumin (PTCER(alb)). Gallium 71-73 inhibitor of carbonic anhydrase Canis lupus familiaris 86-97 9490740-6 1998 RGA was found to be a member of the VHIID regulatory family, which includes the radial root organizing gene SCARECROW and another GA signal transduction repressor, GAI. Gallium 1-3 GRAS family transcription factor family protein Arabidopsis thaliana 164-167 9530956-2 1998 The MUC2 peptide (PTTTPISTTTMVTPTPTPTC) was glycosylated in vitro using concentrated alpha-N-acetylgalactosaminyltransferases activity from porcine submaxillary glands which resulted in the incorporation of 8-9 mol of Ga/NAc. Gallium 218-220 mucin 2 Mus musculus 4-8 9353884-10 1997 These results indicate that the transport of non-transferrin bound gallium is an important mechanism for gallium uptake into brain. Gallium 67-74 transferrin Rattus norvegicus 49-60 9389651-5 1997 Genetic analysis indicates that GAI is a repressor of GA responses, that GA can release this repression, and that gai is a mutant repressor that is relatively resistant to the effects of GA. Gallium 54-56 GRAS family transcription factor family protein Arabidopsis thaliana 32-35 9389651-5 1997 Genetic analysis indicates that GAI is a repressor of GA responses, that GA can release this repression, and that gai is a mutant repressor that is relatively resistant to the effects of GA. Gallium 54-56 GRAS family transcription factor family protein Arabidopsis thaliana 32-35 9486092-2 1997 The aim of the study was to determine the role of increased microvascular protein permeability, as measured by the 67gallium (Ga)-transferrin pulmonary leak index, in pneumonia and associated adult respiratory distress syndrome (ARDS). Gallium 126-128 transferrin Homo sapiens 130-141 9353884-10 1997 These results indicate that the transport of non-transferrin bound gallium is an important mechanism for gallium uptake into brain. Gallium 105-112 transferrin Rattus norvegicus 49-60 8799194-3 1996 A semidominant mutation at the GIBBERELLIN INSENSITIVE (GAI) locus results in plants resembling GA-deficient mutants but exhibiting reduced sensitivity to GA. Gallium 96-98 GRAS family transcription factor family protein Arabidopsis thaliana 56-59 9286110-5 1997 Treatments with gibberellin (GA) and paclobutrazol, a GA biosynthesis inhibitor, as well as crosses with GA-deficient mutants indicate that FPF1 is involved in a GA-dependent signaling pathway and modulates a GA response in apical meristems during the transition to flowering. Gallium 29-31 flowering promoting factor 1 Arabidopsis thaliana 140-144 9286110-5 1997 Treatments with gibberellin (GA) and paclobutrazol, a GA biosynthesis inhibitor, as well as crosses with GA-deficient mutants indicate that FPF1 is involved in a GA-dependent signaling pathway and modulates a GA response in apical meristems during the transition to flowering. Gallium 54-56 flowering promoting factor 1 Arabidopsis thaliana 140-144 9286110-5 1997 Treatments with gibberellin (GA) and paclobutrazol, a GA biosynthesis inhibitor, as well as crosses with GA-deficient mutants indicate that FPF1 is involved in a GA-dependent signaling pathway and modulates a GA response in apical meristems during the transition to flowering. Gallium 54-56 flowering promoting factor 1 Arabidopsis thaliana 140-144 9106752-0 1997 Gallium-transferrin binding in treated and untreated Parkinson"s disease. Gallium 0-7 transferrin Homo sapiens 8-19 9106752-1 1997 The binding of gallium (Ga) to transferrin (Tf) was studied in plasma from control patients, in patients with untreated Parkinson"s disease (PD) and in patients with PD treated either with levodopa (L-dopa) alone or in combination with selegiline. Gallium 15-22 transferrin Homo sapiens 31-42 9106752-1 1997 The binding of gallium (Ga) to transferrin (Tf) was studied in plasma from control patients, in patients with untreated Parkinson"s disease (PD) and in patients with PD treated either with levodopa (L-dopa) alone or in combination with selegiline. Gallium 15-22 transferrin Homo sapiens 44-46 9106752-1 1997 The binding of gallium (Ga) to transferrin (Tf) was studied in plasma from control patients, in patients with untreated Parkinson"s disease (PD) and in patients with PD treated either with levodopa (L-dopa) alone or in combination with selegiline. Gallium 24-26 transferrin Homo sapiens 31-42 9106752-1 1997 The binding of gallium (Ga) to transferrin (Tf) was studied in plasma from control patients, in patients with untreated Parkinson"s disease (PD) and in patients with PD treated either with levodopa (L-dopa) alone or in combination with selegiline. Gallium 24-26 transferrin Homo sapiens 44-46 9106752-2 1997 Mean percentage Ga-Tf binding was significantly reduced in untreated and treated PD compared with controls. Gallium 16-18 transferrin Homo sapiens 19-21 8874204-0 1996 Modulation of in vitro and in vivo T-cell responses by transferrin-gallium and gallium nitrate. Gallium 67-74 transferrin Homo sapiens 55-66 8874204-4 1996 Since gallium binds to transferrin in vivo, in vitro studies evaluated the effect of transferrin-gallium (Tf-Ga) on human T cells. Gallium 6-13 transferrin Homo sapiens 23-34 8874204-4 1996 Since gallium binds to transferrin in vivo, in vitro studies evaluated the effect of transferrin-gallium (Tf-Ga) on human T cells. Gallium 97-104 transferrin Homo sapiens 85-96 9115286-0 1997 Resistance to the antitumor agent gallium nitrate in human leukemic cells is associated with decreased gallium/iron uptake, increased activity of iron regulatory protein-1, and decreased ferritin production. Gallium 34-41 aconitase 1 Homo sapiens 146-171 9115286-6 1997 In both S and R cells, gallium inhibited cellular 59Fe uptake, increased ferritin mRNA and protein, and decreased IRP-1 binding activity. Gallium 23-30 aconitase 1 Homo sapiens 114-119 9115286-7 1997 Gallium uptake by R cells was markedly diminished; however, the sensitivity of R cells to gallium could be restored by increasing their uptake of gallium with excess transferrin. Gallium 90-97 transferrin Homo sapiens 166-177 9115286-10 1997 Furthermore, since gallium has divergent effects on iron uptake and ferritin synthesis, its action may also include a direct effect on ferritin mRNA induction and IRP-1 activity. Gallium 19-26 aconitase 1 Homo sapiens 163-168 9193363-0 1997 Early restaging gallium scans predict outcome in poor-prognosis patients with aggressive non-Hodgkin"s lymphoma treated with high-dose CHOP chemotherapy. Gallium 16-23 DNA damage inducible transcript 3 Homo sapiens 135-139 11669706-0 1997 Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III). Gallium 60-67 mitochondrially encoded cytochrome c oxidase III Homo sapiens 68-71 11669706-0 1997 Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III). Gallium 60-67 mitochondrially encoded cytochrome c oxidase III Homo sapiens 68-71 9381969-5 1997 Gallium, indium and the antineoplastic agent cisplatin were bound to the iron binding site of transferrin and inhibit the growth of malignant carcinoma cell lines. Gallium 0-7 transferrin Homo sapiens 94-105 8799194-4 1996 Recessive mutations at the SPINDLY (SPY) locus cause a phenotype that is consistent with constitutive activation of GA signal transduction. Gallium 116-118 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 27-34 8799194-4 1996 Recessive mutations at the SPINDLY (SPY) locus cause a phenotype that is consistent with constitutive activation of GA signal transduction. Gallium 116-118 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 36-39 8756507-7 1996 The GA-deficient mutants ga1-5 and ga4-1 and the GA-insensitive mutant gai-1 exhibit delayed onset of abaxial trichomes when grown in LD conditions. Gallium 4-6 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 25-30 8690320-11 1996 (3) Two common alleles in Esterase D (EsD) polymorphism, EsD1 and EsD2 were characterized by the substitution of one amino acid (Gly-Glu) caused by the point mutation of one nucleotide (G-A). Gallium 186-189 esterase D Homo sapiens 26-36 8706051-10 1996 In one patient, a lesion in the femur, which was detected by computed tomography (CT) and gallium-67 scans, was also seen on the CD19 scan from 1 h after administration of the radioimmunoconjugate onwards. Gallium 90-97 CD19 molecule Homo sapiens 129-133 9816262-2 1996 Transferrin, the iron transport protein, increases gallium uptake by cells, whereas pyridoxal isonicotinoyl hydrazone (PIH), an iron chelator, transports iron into cells. Gallium 51-58 transferrin Homo sapiens 0-11 9816262-5 1996 One mg/ml transferrin decreased the 50% inhibitory concentration of gallium nitrate from 1650 to 75 micrometer in gallium-resistant cells and from 190 to 150 micrometer in gallium-sensitive cells. Gallium 68-75 transferrin Homo sapiens 10-21 9816262-5 1996 One mg/ml transferrin decreased the 50% inhibitory concentration of gallium nitrate from 1650 to 75 micrometer in gallium-resistant cells and from 190 to 150 micrometer in gallium-sensitive cells. Gallium 114-121 transferrin Homo sapiens 10-21 9816262-6 1996 Transferrin also enhanced the cytotoxicity of gallium even at drug concentrations that were not growth inhibitory. Gallium 46-53 transferrin Homo sapiens 0-11 7549486-2 1995 The Dwarf3 (D3) gene of maize encodes an early step in the GA biosynthesis pathway. Gallium 59-61 ent-kaurenoic acid oxidase Zea mays 4-10 8580773-5 1996 Treatment with abscisic acid (ABA) antagonizes the GA-induced suppression of the GAD1 and GAD2 RNAs. Gallium 51-53 glutamate decarboxylase isoform2 Solanum lycopersicum 90-94 8788232-3 1995 Gallium inhibited dose-dependently the secretion of IL-6, TNF alpha, and NO from the LPS-induced macrophage-like RAW 264 cells. Gallium 0-7 interleukin 6 Mus musculus 52-56 8788232-3 1995 Gallium inhibited dose-dependently the secretion of IL-6, TNF alpha, and NO from the LPS-induced macrophage-like RAW 264 cells. Gallium 0-7 tumor necrosis factor Mus musculus 58-67 8788232-6 1995 Liposomal gallium-NTA inhibited the expression of iNOS by the macrophages, while other formulations of gallium had no effect. Gallium 10-17 nitric oxide synthase 2, inducible Mus musculus 50-54 8749946-12 1995 CONCLUSIONS: Intravesically administered gallium might be an effective therapy for bladder cancer, because its cytotoxicity is determined not by the amount of Tf receptor but by the gallium concentration and the duration of gallium exposure. Gallium 41-48 transferrin Homo sapiens 159-161 8806110-11 1996 Both exogenous and endogenous TF and TFR play an important role in Ga uptake in these cells. Gallium 67-69 transferrin Homo sapiens 30-32 8806110-11 1996 Both exogenous and endogenous TF and TFR play an important role in Ga uptake in these cells. Gallium 67-69 transferrin receptor Homo sapiens 37-40 8519674-1 1995 Gallium-67 (67Ga) accumulates in malignant tissues via the transferrin receptor without need for a monoclonal antibody and emits cytotoxic low-energy electrons. Gallium 0-7 transferrin Homo sapiens 59-70 7604047-11 1995 Expression of the GA5 gene in Ara-bidopsis leaves was enhanced after plants were transferred from short to long days; it was reduced by GA4 treatment, suggesting end-product repression in the GA biosynthetic pathway. Gallium 18-20 gibberellin 3-oxidase 1 Arabidopsis thaliana 136-139 8749946-2 1995 Because bladder cancer has many transferrin (Tf) receptors and gallium has been reported to bind avidly with Tf receptors, gallium cytotoxicity and the possibility of intravesical instillation therapy with gallium nitrate were studied in vitro. Gallium 63-70 transferrin Homo sapiens 109-111 8749946-9 1995 At lower concentrations of gallium, the effect was related to the amount of Tf and the level of Tf receptor expression of the cells. Gallium 27-34 transferrin Homo sapiens 76-78 8749946-9 1995 At lower concentrations of gallium, the effect was related to the amount of Tf and the level of Tf receptor expression of the cells. Gallium 27-34 transferrin Homo sapiens 96-98 7630935-7 1995 In the floral shoots of the ga1-2 mutant, transcript levels corresponding to each cDNA decreased dramatically after GA3 application, suggesting that GA biosynthesis may be controlled, at least in part, through down-regulation of the expression of the 20-oxidase genes. Gallium 116-118 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 28-33 7538455-1 1995 The authors report on two non-Hodgkin"s lymphoma cases which showed markedly enhanced Ga-67 uptake of granulopoietic area induced by recombinant human granulocyte colony-stimulating factor (rhG-CSF) administration. Gallium 86-88 colony stimulating factor 3 Homo sapiens 151-188 7727751-6 1995 At least two of the GASA genes are activated in GA-deficient mutant ga5, as early as 4 to 8 h after spraying with 50 microM GA3. Gallium 20-22 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 68-71 7727751-6 1995 At least two of the GASA genes are activated in GA-deficient mutant ga5, as early as 4 to 8 h after spraying with 50 microM GA3. Gallium 20-22 GA requiring 3 Arabidopsis thaliana 124-127 7756830-2 1995 Complementation analysis with genetically characterized GA-responsive mutants revealed that the transgenic plant has an insertional mutation (ga4-2) that is an allele of the ga4 locus. Gallium 56-58 gibberellin 3-oxidase 1 Arabidopsis thaliana 142-145 7756830-2 1995 Complementation analysis with genetically characterized GA-responsive mutants revealed that the transgenic plant has an insertional mutation (ga4-2) that is an allele of the ga4 locus. Gallium 56-58 gibberellin 3-oxidase 1 Arabidopsis thaliana 174-177 7756830-8 1995 This conclusion is in agreement with a biochemical study that indicated that the ga4 mutant is deficient in 3 beta-hydroxylase in the GA biosynthetic pathway of Arabidopsis. Gallium 134-136 gibberellin 3-oxidase 1 Arabidopsis thaliana 81-84 7818516-1 1995 The conformation in solution of three different metal(III)-transferrins, namely aluminum(III), gallium(III) and indium(III) transferrin, was investigated by absorption, CD, 1H NMR and 13C NMR spectroscopies. Gallium 95-102 transferrin Homo sapiens 59-70 7756830-10 1995 Unexpectedly, a higher level of transcription was detected in the ethyl methanesulfonate-induced ga4 mutant, and this overexpression was repressed by treatment with exogenous GA. Gallium 175-177 gibberellin 3-oxidase 1 Arabidopsis thaliana 97-100 8400871-4 1993 The spy-1 allele is partially epistatic to the ga1-2 mutation, which causes GA deficiency. Gallium 76-78 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 4-7 7809837-10 1995 The findings substantiate that gallium may reduce PTH release by stabilization of the plasma membrane rather than by interference with the surface cation receptor mediating Ca2+ regulation of the secretion. Gallium 31-38 parathyroid hormone Homo sapiens 50-53 10018253-0 1994 Implication of gallium results on the possibility of observing day-night matter oscillations at SNO, Super-Kamiokande, and Borexino. Gallium 15-22 strawberry notch homolog 1 Homo sapiens 96-99 8293354-5 1993 However, animals that received gallium both before and during the healing phase had less well-mineralized bones at 18 hours, and by 72 hours, they had lesser increases in osteocalcin and mineral content, which was associated with smaller crystal sizes, than did any animal that did not receive gallium at any time. Gallium 31-38 bone gamma-carboxyglutamate protein Rattus norvegicus 171-182 8279755-14 1993 Other transferrin complexes and conjugates of gallium, indium, and daunorubicin have also shown growth inhibition in tissue culture and animals. Gallium 46-53 transferrin Homo sapiens 6-17 8280853-3 1993 Non-transferrin bound gallium species were identified as non-transportable phosphate or silicate. Gallium 22-29 transferrin Homo sapiens 4-15 8379943-0 1993 Modulation of transferrin receptor mRNA by transferrin-gallium in human myeloid HL60 and lymphoid CCRF-CEM leukaemic cells. Gallium 55-62 transferrin receptor Homo sapiens 14-34 8379943-0 1993 Modulation of transferrin receptor mRNA by transferrin-gallium in human myeloid HL60 and lymphoid CCRF-CEM leukaemic cells. Gallium 55-62 transferrin Homo sapiens 14-25 8379943-1 1993 Gallium binds to the iron transport protein transferrin (Tf), is incorporated into cells through transferrin receptors (TfR) and inhibits iron-dependent DNA synthesis. Gallium 0-7 transferrin Homo sapiens 44-55 8379943-1 1993 Gallium binds to the iron transport protein transferrin (Tf), is incorporated into cells through transferrin receptors (TfR) and inhibits iron-dependent DNA synthesis. Gallium 0-7 transferrin Homo sapiens 57-59 8379943-1 1993 Gallium binds to the iron transport protein transferrin (Tf), is incorporated into cells through transferrin receptors (TfR) and inhibits iron-dependent DNA synthesis. Gallium 0-7 transferrin receptor Homo sapiens 97-118 8379943-1 1993 Gallium binds to the iron transport protein transferrin (Tf), is incorporated into cells through transferrin receptors (TfR) and inhibits iron-dependent DNA synthesis. Gallium 0-7 transferrin receptor Homo sapiens 120-123 8379943-9 1993 Our studies suggest that in HL60 cells, gallium regulates TfR expression at the post-transcriptional level by mechanisms which require de novo protein synthesis and involve interaction with iron. Gallium 40-47 transferrin receptor Homo sapiens 58-61 12228362-2 1995 The relative transcript levels of wali1 (encoding a plant metallothionein-like protein), wali3 and wali5 (putative Bowman-Birk proteinase inhibitors), and wali4 (phenylalanine ammonialyase) increased in root tips of wheat after 2-d treatments with toxic levels of all other metals tested (Cd, Fe, Zn, Cu, Ga, In, and La). Gallium 305-307 metallothionein-like protein 1 Triticum aestivum 34-39 12228362-2 1995 The relative transcript levels of wali1 (encoding a plant metallothionein-like protein), wali3 and wali5 (putative Bowman-Birk proteinase inhibitors), and wali4 (phenylalanine ammonialyase) increased in root tips of wheat after 2-d treatments with toxic levels of all other metals tested (Cd, Fe, Zn, Cu, Ga, In, and La). Gallium 305-307 wali4 Triticum aestivum 155-160 8205543-7 1994 The addition of IFN-alpha to this concentration of gallium significantly increased the gallium-induced block of iron uptake, resulting in an increase in transferrin receptors and an inhibition of cell growth. Gallium 51-58 interferon alpha 1 Homo sapiens 16-25 8205543-7 1994 The addition of IFN-alpha to this concentration of gallium significantly increased the gallium-induced block of iron uptake, resulting in an increase in transferrin receptors and an inhibition of cell growth. Gallium 51-58 transferrin Homo sapiens 153-164 8205543-7 1994 The addition of IFN-alpha to this concentration of gallium significantly increased the gallium-induced block of iron uptake, resulting in an increase in transferrin receptors and an inhibition of cell growth. Gallium 87-94 interferon alpha 1 Homo sapiens 16-25 8205543-7 1994 The addition of IFN-alpha to this concentration of gallium significantly increased the gallium-induced block of iron uptake, resulting in an increase in transferrin receptors and an inhibition of cell growth. Gallium 87-94 transferrin Homo sapiens 153-164 8164693-6 1994 Addition of a GA-rich element present in many HSV immediate-early gene enhancers synergistically stimulated VP16-activated transcription. Gallium 14-16 host cell factor C1 Homo sapiens 108-112 8053130-5 1994 In C cells of both vehicle- and gallium-treated tumor-bearing mice, immunoreactive staining was decreased for calcitonin, calcitonin gene-related peptide, and chromogranin A, whereas there was a moderate increase in staining for neuron-specific enolase. Gallium 32-39 chromogranin A Mus musculus 159-173 8053130-5 1994 In C cells of both vehicle- and gallium-treated tumor-bearing mice, immunoreactive staining was decreased for calcitonin, calcitonin gene-related peptide, and chromogranin A, whereas there was a moderate increase in staining for neuron-specific enolase. Gallium 32-39 enolase 2, gamma neuronal Mus musculus 229-252 8400871-4 1993 The spy-1 allele is partially epistatic to the ga1-2 mutation, which causes GA deficiency. Gallium 76-78 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 47-52 8400871-5 1993 In addition, the spy-1 mutation can simultaneously suppress the effects of the ga1-2 mutation and paclobutrazol treatment, which inhibit different steps in the GA biosynthesis pathway. Gallium 160-162 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 17-20 8400871-5 1993 In addition, the spy-1 mutation can simultaneously suppress the effects of the ga1-2 mutation and paclobutrazol treatment, which inhibit different steps in the GA biosynthesis pathway. Gallium 160-162 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 79-84 8400871-6 1993 This observation suggests that spy-1 activates a basal level of GA signal transduction that is independent of GA. Gallium 64-66 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 31-34 1337663-8 1992 Since transferrin receptor increases on gallium treated iron requiring cells in vitro, we assessed cell surface transferrin receptor on peripheral blood lymphocytes by measuring fluorescent transferrin receptor antibody binding. Gallium 40-47 transferrin Homo sapiens 6-17 8381250-5 1993 Among several different metals examined, gallium was unique in its ability to reduce osteocalcin mRNA levels without decreasing levels of other mRNAs synthesized by ROS 17/2.8 cells. Gallium 41-48 bone gamma-carboxyglutamate protein Rattus norvegicus 85-96 1517848-0 1992 Gallium-67 distribution in a man with a decrease in both transferrin and hepatic gallium-67 concentration. Gallium 0-7 transferrin Homo sapiens 57-68 1337663-1 1992 Gallium, when bound to transferrin, has been previously shown to cause tumor cell cytotoxicity by preventing cellular uptake of transferrin bound iron in vitro. Gallium 0-7 transferrin Homo sapiens 23-34 1337663-1 1992 Gallium, when bound to transferrin, has been previously shown to cause tumor cell cytotoxicity by preventing cellular uptake of transferrin bound iron in vitro. Gallium 0-7 transferrin Homo sapiens 128-139 1337663-4 1992 Atomic analysis of iron and gallium content of Sephadex G-150 fractions of treatment sera indicate that about an equimolar amount of gallium and iron are associated with transferrin. Gallium 133-140 transferrin Homo sapiens 170-181 1337663-5 1992 These gallium and iron concentrations result in inhibition of transferrin mediated iron uptake in vitro, and in vivo allow for > 90% saturation of transferrin with metal. Gallium 6-13 transferrin Homo sapiens 62-73 1337663-5 1992 These gallium and iron concentrations result in inhibition of transferrin mediated iron uptake in vitro, and in vivo allow for > 90% saturation of transferrin with metal. Gallium 6-13 transferrin Homo sapiens 150-161 1337290-3 1992 In thrombin activated platelets, evidence suggests that severing of F-actin by gelsolin increases GA complex, creates one-end actin nucleus and one cryptic+end actin nucleus per cut, and then dissociates to yield free+ends to nucleate rapid actin assembly. Gallium 98-100 gelsolin Homo sapiens 79-87 8227174-6 1993 In addition, gallium treatment increased steady-state mRNA levels for fibronectin and type I procollagen chains in primary rat calvarial osteoblast-enriched cultures, the ROS 17/2.8 osteoblastic osteosarcoma line, and nontransformed human dermal fibroblasts. Gallium 13-20 fibronectin 1 Rattus norvegicus 70-81 16653111-4 1992 Different methods of GA application (spray, injection, capillary wick, and excised leaf systems) produced similar effects on SPS activity of soybean leaves. Gallium 21-23 probable sucrose-phosphate synthase Glycine max 125-128 16653111-5 1992 Protein synthesis in soybean leaves appeared to be necessary for GA-promoted SPS activity because gibberellic acid only partially reversed the inhibitory effect of pretreatment with cycloheximide. Gallium 65-67 probable sucrose-phosphate synthase Glycine max 77-80 10002463-0 1992 Atomic structure of the alpha -Ga(001) surface investigated by scanning tunneling microscopy: Direct evidence for the existence of Ga2 molecules in solid gallium. Gallium 154-161 electron transfer flavoprotein subunit alpha Homo sapiens 131-134 1526029-0 1992 Effect of pH and citrate on binding of iron and gallium by transferrin in serum. Gallium 48-55 transferrin Homo sapiens 59-70 1377710-4 1992 Ga administered in vivo suppressed myelin basic protein (MBP) and purified protein derivative-specific lymphocyte proliferative responses in vitro. Gallium 0-2 myelin basic protein Homo sapiens 35-55 1627803-0 1992 Regulatory effects of gallium on transferrin-independent iron uptake by human leukemic HL60 cells. Gallium 22-29 transferrin Homo sapiens 33-44 1627803-1 1992 Gallium, a pharmacologically important metal, resembles iron with respect to transferrin (Tf) binding and Tf receptor-mediated cellular uptake. Gallium 0-7 transferrin Homo sapiens 77-88 1627803-1 1992 Gallium, a pharmacologically important metal, resembles iron with respect to transferrin (Tf) binding and Tf receptor-mediated cellular uptake. Gallium 0-7 transferrin Homo sapiens 90-92 1627803-1 1992 Gallium, a pharmacologically important metal, resembles iron with respect to transferrin (Tf) binding and Tf receptor-mediated cellular uptake. Gallium 0-7 transferrin Homo sapiens 106-108 1627803-2 1992 In the present study, we examined the effect of gallium on Tf-independent iron uptake by HL60 cells. Gallium 48-55 transferrin Homo sapiens 59-61 1377710-4 1992 Ga administered in vivo suppressed myelin basic protein (MBP) and purified protein derivative-specific lymphocyte proliferative responses in vitro. Gallium 0-2 myelin basic protein Homo sapiens 57-60 1377710-5 1992 Addition of Ga to MBP-specific T lymphocyte line cultures at various times after initiation of culture revealed that Ga exerts an effect at an early stage of cellular activation. Gallium 117-119 myelin basic protein Homo sapiens 18-21 1596025-2 1992 We evaluated pulmonary vascular permeability with positron emission tomography (PET) in 16 patients with interstitial lung disease (ILD) by measuring the pulmonary transcapillary escape rate (PTCER) for transferrin labeled with gallium-68. Gallium 228-235 transferrin Homo sapiens 203-214 1613579-0 1992 Establishment and characterization of monoclonal antibodies against an octahedral gallium chelate suitable for immunoscintigraphy with PET. Gallium 82-89 thyroid stimulating hormone receptor Mus musculus 135-138 2066803-1 1991 When gallium citrate is injected intravenously the gallium is rapidly transchelated to transferrin. Gallium 5-12 transferrin Homo sapiens 87-98 1352947-4 1992 Since GA is transformed to gamma-aminobutyric acid and CO2 under the catalytic activity of GAD, the rate of GA consumption in solution, monitored by the GAO biosensor, represents a reliable measure of GAD catalytic activity. Gallium 6-8 glutamate decarboxylase 1 Homo sapiens 91-94 1352947-4 1992 Since GA is transformed to gamma-aminobutyric acid and CO2 under the catalytic activity of GAD, the rate of GA consumption in solution, monitored by the GAO biosensor, represents a reliable measure of GAD catalytic activity. Gallium 6-8 glutamate decarboxylase 1 Homo sapiens 201-204 1352947-4 1992 Since GA is transformed to gamma-aminobutyric acid and CO2 under the catalytic activity of GAD, the rate of GA consumption in solution, monitored by the GAO biosensor, represents a reliable measure of GAD catalytic activity. Gallium 91-93 glutamate decarboxylase 1 Homo sapiens 201-204 1346299-0 1992 Gallium (aluminium) transferrin binding in Alzheimer"s disease. Gallium 0-7 transferrin Homo sapiens 20-31 1627803-3 1992 In contrast to the inhibitory effect of Tf-gallium on Tf-iron uptake, gallium nitrate, in a time-, temperature-, and concentration-dependent manner, stimulated Tf-independent uptake of iron-nitrilotriacetic acid (Fe-NTA). Gallium 43-50 transferrin Homo sapiens 40-42 1627803-7 1992 Ferric chloride stimulated Tf-independent gallium uptake. Gallium 42-49 transferrin Homo sapiens 27-29 1627803-9 1992 Gallium and iron appear to share the same Tf-independent cellular uptake system in HL60 cells. Gallium 0-7 transferrin Homo sapiens 42-44 1627803-10 1992 Exposure of cells to gallium results in the activation of cell membrane non-Tf iron carriers that may play a role in overcoming the Tf-independent growth-inhibitory effects of gallium. Gallium 21-28 transferrin Homo sapiens 76-78 1627803-10 1992 Exposure of cells to gallium results in the activation of cell membrane non-Tf iron carriers that may play a role in overcoming the Tf-independent growth-inhibitory effects of gallium. Gallium 21-28 transferrin Homo sapiens 132-134 1627803-10 1992 Exposure of cells to gallium results in the activation of cell membrane non-Tf iron carriers that may play a role in overcoming the Tf-independent growth-inhibitory effects of gallium. Gallium 176-183 transferrin Homo sapiens 76-78 1627803-10 1992 Exposure of cells to gallium results in the activation of cell membrane non-Tf iron carriers that may play a role in overcoming the Tf-independent growth-inhibitory effects of gallium. Gallium 176-183 transferrin Homo sapiens 132-134 1737998-1 1992 The transfer coefficients (Kin) for the uptake of gallium-67 (67Ga) into brain and CSF were determined in unanesthetized male Fischer-344 rats fed either a normal or a low-Ca diet. Gallium 50-57 Kin17 DNA and RNA binding protein Rattus norvegicus 27-30 1682757-0 1991 Transferrin-gallium binding in Alzheimer"s disease. Gallium 12-19 transferrin Homo sapiens 0-11 1933878-1 1991 Our previous studies of the mechanism of cell growth inhibition by gallium have suggested that the block in cellular iron uptake induced by transferrin-gallium results in an inhibition of the iron-dependent M2 subunit of ribonucleotide reductase. Gallium 67-74 transferrin Mus musculus 140-151 1933878-1 1991 Our previous studies of the mechanism of cell growth inhibition by gallium have suggested that the block in cellular iron uptake induced by transferrin-gallium results in an inhibition of the iron-dependent M2 subunit of ribonucleotide reductase. Gallium 152-159 transferrin Mus musculus 140-151 2066803-8 1991 This suggests the gallium-transferrin complex may not be sufficiently stable for quantitative measures of vascular permeability, particularly if the bicarbonate concentration is low. Gallium 18-25 transferrin Homo sapiens 26-37 2021708-7 1991 Similarly, the number of osteoclast-like cells and the TRAP activity in the gallium-containing bone particle implants at 21 days were increased relative to controls. Gallium 76-83 acid phosphatase 5, tartrate resistant Rattus norvegicus 55-59 1849808-8 1991 Patients with positive gallium-67 uptake or bilateral hilar lymphadenopathy had high levels of either serum IFN-gamma or lysozyme. Gallium 23-30 interferon gamma Homo sapiens 108-117 1996560-2 1991 It appeared that expression of CD71 phenotype was closely related to the positivity of gallium scan before therapy. Gallium 87-94 transferrin receptor Homo sapiens 31-35 2205309-6 1990 Eighty percent of the mutations involved substitution of aspartic acid for glycine (G----A) in the 12th or 13th codons of N-ras or K-ras. Gallium 84-90 NRAS proto-oncogene, GTPase Homo sapiens 122-127 1645976-0 1991 Targeting iron-dependent DNA synthesis with gallium and transferrin-gallium. Gallium 68-75 transferrin Homo sapiens 56-67 1645976-2 1991 Gallium, a metal which resembles iron with respect to transferrin (Tf) binding, cellular uptake by the Tf receptor and incorporation into ferritin, blocks the cellular uptake of iron and inhibits cell growth. Gallium 0-7 transferrin Homo sapiens 54-65 2253599-0 1990 Inhibition of liver, kidney, and erythrocyte delta-aminolevulinic acid dehydratase (porphobilinogen synthase) by gallium in the rat. Gallium 113-120 aminolevulinate dehydratase Rattus norvegicus 45-82 2253599-0 1990 Inhibition of liver, kidney, and erythrocyte delta-aminolevulinic acid dehydratase (porphobilinogen synthase) by gallium in the rat. Gallium 113-120 aminolevulinate dehydratase Rattus norvegicus 84-108 2253599-3 1990 This study was undertaken to evaluate in vivo the role of gallium alone in ALAD inhibition and increased urinary excretion of ALA. Gallium 58-65 aminolevulinate dehydratase Rattus norvegicus 75-79 2253599-10 1990 Lineweaver-Burk analyses of renal and hepatic ALAD activities in the absence and presence of gallium indicated that the inhibition of ALAD by this element is noncompetitive (same Km, decreased Vmax). Gallium 93-100 aminolevulinate dehydratase Rattus norvegicus 134-138 2253599-11 1990 Gallium was shown to possess an inhibition constant (Ki) of approximately 3 microns for ALAD, similar to the Ki obtained for lead in other studies. Gallium 0-7 aminolevulinate dehydratase Rattus norvegicus 88-92 2253599-12 1990 Incubation of ALAD in vitro with gallium and lead, an active thiol group inhibitor, resulted in a greater inhibition of the enzyme. Gallium 33-40 aminolevulinate dehydratase Rattus norvegicus 14-18 2253599-13 1990 Further in vitro studies demonstrated the attenuation of gallium inhibition of hepatic and renal ALAD by zinc, suggesting that the mechanism of gallium action may involve competition for or displacement of zinc from the sulfhydryl group of the enzyme active site. Gallium 57-64 aminolevulinate dehydratase Rattus norvegicus 97-101 2253599-13 1990 Further in vitro studies demonstrated the attenuation of gallium inhibition of hepatic and renal ALAD by zinc, suggesting that the mechanism of gallium action may involve competition for or displacement of zinc from the sulfhydryl group of the enzyme active site. Gallium 144-151 aminolevulinate dehydratase Rattus norvegicus 97-101 2253599-14 1990 Since ALAD inhibition occurred at doses at which no histopathologic changes were evident, the determination of ALAD activity in various tissues, including blood, may be of potential value as a biomarker of exposure/toxicity to metals such as gallium. Gallium 242-249 aminolevulinate dehydratase Rattus norvegicus 6-10 2253599-14 1990 Since ALAD inhibition occurred at doses at which no histopathologic changes were evident, the determination of ALAD activity in various tissues, including blood, may be of potential value as a biomarker of exposure/toxicity to metals such as gallium. Gallium 242-249 aminolevulinate dehydratase Rattus norvegicus 111-115 2253599-15 1990 The effect of chemical form and route of exposure of gallium and effects of other Group III metals on inhibition of ALAD and excretion of ALA is discussed. Gallium 53-60 aminolevulinate dehydratase Rattus norvegicus 116-120 1698536-1 1990 Earlier studies have shown that transferrin-gallium inhibits cellular iron incorporation and blocks DNA synthesis by decreasing the activity of the iron-dependent M2 subunit of ribonucleotide reductase. Gallium 44-51 transferrin Homo sapiens 32-43 2213185-0 1990 A new myocardial imaging agent: synthesis, characterization, and biodistribution of gallium-68-BAT-TECH. Gallium 84-91 pleckstrin homology and RhoGEF domain containing G5 Rattus norvegicus 99-103 2213185-2 1990 Synthesis, radiolabeling, characterization, and biodistribution of a unique gallium complex, [67Ga]BAT-TECH (bis-aminoethanethiol-tetraethyl-cyclohexyl), are described. Gallium 76-83 pleckstrin homology and RhoGEF domain containing G5 Rattus norvegicus 103-107 2205309-6 1990 Eighty percent of the mutations involved substitution of aspartic acid for glycine (G----A) in the 12th or 13th codons of N-ras or K-ras. Gallium 84-90 KRAS proto-oncogene, GTPase Homo sapiens 131-136 2393846-3 1990 In the transferrin system, significantly higher transferrin-gallium concentrations were required to achieve the same inhibitory effects. Gallium 60-67 transferrin Homo sapiens 48-59 2393846-2 1990 For the human cell line in ferric citrate medium, 50% growth inhibition achieved in the presence of transferrin-gallium represented a gallium concentration 80-fold lower than the concentration required when gallium nitrate was added. Gallium 112-119 transferrin Homo sapiens 100-111 2393846-2 1990 For the human cell line in ferric citrate medium, 50% growth inhibition achieved in the presence of transferrin-gallium represented a gallium concentration 80-fold lower than the concentration required when gallium nitrate was added. Gallium 134-141 transferrin Homo sapiens 100-111 2164439-1 1990 We have shown that transferrin-gallium (Tf-Ga) blocks DNA synthesis through inhibition of cellular iron incorporation and a diminution in the activity of the iron-dependent M2 subunit of ribonucleotide reductase. Gallium 31-38 transferrin Homo sapiens 19-30 2393846-4 1990 Monoclonal antibody to the transferrin receptor significantly decreased the growth inhibiting effect of transferrin-gallium in the mouse ferric citrate system. Gallium 116-123 transferrin Mus musculus 27-38 2393846-4 1990 Monoclonal antibody to the transferrin receptor significantly decreased the growth inhibiting effect of transferrin-gallium in the mouse ferric citrate system. Gallium 116-123 transferrin Mus musculus 104-115 2393846-5 1990 Thus, under very different culture conditions, gallium and iron appear to compete via the transferrin-transferrin receptor pathway for cellular uptake. Gallium 47-54 transferrin Homo sapiens 90-101 2393846-5 1990 Thus, under very different culture conditions, gallium and iron appear to compete via the transferrin-transferrin receptor pathway for cellular uptake. Gallium 47-54 transferrin Homo sapiens 102-113 2393846-6 1990 The growth inhibitory effects of gallium are markedly potentiated when the metal is taken up by functional transferrin receptors even in cells continuously cultured in transferrin-free medium. Gallium 33-40 transferrin Homo sapiens 107-118 2393846-6 1990 The growth inhibitory effects of gallium are markedly potentiated when the metal is taken up by functional transferrin receptors even in cells continuously cultured in transferrin-free medium. Gallium 33-40 transferrin Homo sapiens 168-179 1971410-0 1990 Gallium-transferrin binding in Alzheimer disease. Gallium 0-7 transferrin Homo sapiens 8-19 1969510-0 1990 Defective gallium-transferrin binding in Alzheimer disease and Down syndrome: possible mechanism for accumulation of aluminium in brain. Gallium 10-17 transferrin Homo sapiens 18-29 2133736-0 1990 [The relationship between Ga-67 uptake and transferrin receptors in cultured cells]. Gallium 26-28 transferrin Rattus norvegicus 43-54 2133736-11 1990 These results suggest a correlation between the number of Tf receptors and Ga-67 uptake in the proliferative and quiescent phases it indicates that Ga-67 uptake into the cells depends on the number of Tf receptors. Gallium 75-77 transferrin Rattus norvegicus 58-60 18964929-6 1990 The gallium content found in tap water was higher than that in raw water. Gallium 4-11 nuclear RNA export factor 1 Homo sapiens 29-32 1969510-2 1990 Gallium-transferrin binding was significantly lower in the Alzheimer (mean [SEM] 7.9 [1.1]%) and Down syndrome groups (6.9 [0.7]%) than in the controls (17.1 [1.6]%), whereas stroke dementia and haemodialysis patients had normal binding. Gallium 0-7 transferrin Homo sapiens 8-19 33812928-1 2021 This research aimed to examine the nutritious supplementary function of 18beta-Glycyrrhetinic acid (18beta-GA) in moderating the myelin sheath destruction and behavioral impairments observed in the cuprizone model of demyelination. Gallium 107-109 olfactory receptor family 7 subfamily D member 10 Mus musculus 72-78 33812928-1 2021 This research aimed to examine the nutritious supplementary function of 18beta-Glycyrrhetinic acid (18beta-GA) in moderating the myelin sheath destruction and behavioral impairments observed in the cuprizone model of demyelination. Gallium 107-109 olfactory receptor family 7 subfamily D member 10 Mus musculus 100-106 33971366-5 2021 Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Gallium 40-42 cryptochrome 1 Arabidopsis thaliana 158-162 33971366-5 2021 Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Gallium 132-134 cryptochrome 1 Arabidopsis thaliana 158-162 33971366-5 2021 Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Gallium 132-134 cryptochrome 1 Arabidopsis thaliana 158-162 33971366-6 2021 Data from our in vitro and in vivo biochemical analyses demonstrate that CRY1 physically interacts with GA receptors-GA INSENSITIVE DWARF 1 proteins (GID1s)-and DELLAs in a blue light-dependent manner. Gallium 104-106 cryptochrome 1 Arabidopsis thaliana 73-77 33971366-9 2021 Taken together, our findings demonstrate that CRY1 signals by stabilizing DELLAs through binding and inactivating GID1s and provide new insight into the mechanism by which blue light antagonizes the function of GA in photomorphogenesis. Gallium 211-213 cryptochrome 1 Arabidopsis thaliana 46-50 33822231-7 2021 Here, we show that GAF1 functions in the GA-dependent flowering pathway by regulating FT and SOC1 expression in Arabidopsis thaliana. Gallium 19-21 AGAMOUS-like 20 Arabidopsis thaliana 93-97 33777525-12 2021 The mTG/GA and its composite hydrogels showed higher compressive moduli than the single-component chitosan and alginate hydrogels. Gallium 8-10 protease, serine 3 Mus musculus 4-7 33803174-0 2021 Nitrogen Dissolution in Liquid Ga and Fe: Comprehensive Ab Initio Analysis, Relevance for Crystallization of GaN. Gallium 31-33 gigaxonin Homo sapiens 109-112 34725194-0 2021 Improving Theranostic Gallium-68/Lutetium-177-Labeled PSMA Inhibitors with an Albumin Binder for Prostate Cancer. Gallium 22-29 folate hydrolase 1 Homo sapiens 54-58 34816513-0 2022 An isolable gallium-substituted nitrilimine and its reactivity with B-H, Si-H and B-B bonds. Gallium 12-19 bleomycin hydrolase Homo sapiens 68-71 34636633-5 2022 Purpose To evaluate the use of FAP inhibitor (FAPI) breast PET/MRI in assessing breast lesions and of FAPI whole-body scanning for lymph node (LN) and distant staging using the ligand gallium 68 (68Ga)-FAPI-46. Gallium 184-191 fibroblast activation protein alpha Homo sapiens 31-34 34400066-2 2022 BACKGROUND AND AIM: Gallium-68 (68Ga)-Prostate Membrane Specific Antigen Positron Emission Tomography/Computed Tomography (68Ga-PSMA PET/CT) is an emerging diagnostic modality which is gaining importance in individualized prostate cancer (PCa) management era. Gallium 20-27 folate hydrolase 1 Homo sapiens 128-132 34910462-13 2021 The complexed Ga was converted to free Ga3+ by a simple UV irradiation method. Gallium 14-16 succinyl-CoA:glutarate-CoA transferase Homo sapiens 39-42 34963428-7 2022 Furthermore, we found that GA inhibited TGF-(Formula: see text)-induced EMT mainly by reducing the phosphorylation of signal transducer and activator of transcription 3 (STAT3), which played an essential role in TGF-(Formula: see text)-induced EMT and cell mobility. Gallium 27-29 signal transducer and activator of transcription 3 Homo sapiens 118-168 34963428-7 2022 Furthermore, we found that GA inhibited TGF-(Formula: see text)-induced EMT mainly by reducing the phosphorylation of signal transducer and activator of transcription 3 (STAT3), which played an essential role in TGF-(Formula: see text)-induced EMT and cell mobility. Gallium 27-29 signal transducer and activator of transcription 3 Homo sapiens 170-175 34963428-8 2022 Mechanistically, GA inhibited the phosphorylation of STAT3 by increasing the expression of Src homology 2 domain-containing protein tyrosine phosphatases 1 and 2 (SHP1 and SHP2). Gallium 17-19 signal transducer and activator of transcription 3 Homo sapiens 53-58 34963428-8 2022 Mechanistically, GA inhibited the phosphorylation of STAT3 by increasing the expression of Src homology 2 domain-containing protein tyrosine phosphatases 1 and 2 (SHP1 and SHP2). Gallium 17-19 protein tyrosine phosphatase non-receptor type 6 Homo sapiens 163-167 34963428-8 2022 Mechanistically, GA inhibited the phosphorylation of STAT3 by increasing the expression of Src homology 2 domain-containing protein tyrosine phosphatases 1 and 2 (SHP1 and SHP2). Gallium 17-19 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 172-176 34963428-9 2022 Therefore, we concluded that GA inhibited TGF-(Formula: see text)-induced EMT and metastasis via the SHP1&SHP2/STAT3/Snail pathway. Gallium 29-31 protein tyrosine phosphatase non-receptor type 6 Homo sapiens 101-105 34963428-9 2022 Therefore, we concluded that GA inhibited TGF-(Formula: see text)-induced EMT and metastasis via the SHP1&SHP2/STAT3/Snail pathway. Gallium 29-31 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 106-110 34963428-9 2022 Therefore, we concluded that GA inhibited TGF-(Formula: see text)-induced EMT and metastasis via the SHP1&SHP2/STAT3/Snail pathway. Gallium 29-31 signal transducer and activator of transcription 3 Homo sapiens 111-116 34963428-9 2022 Therefore, we concluded that GA inhibited TGF-(Formula: see text)-induced EMT and metastasis via the SHP1&SHP2/STAT3/Snail pathway. Gallium 29-31 snail family transcriptional repressor 1 Homo sapiens 117-122 34627953-5 2021 Microsomes, chemical special inhibitors and human recombinant CYPs indicated that GA was mainly metabolized by CYP3A4/5. Gallium 82-84 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 111-119 34627953-7 2021 The CYP3A4 inhibitor ketoconazole significantly inhibited the metabolism of GA. Gallium 76-78 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 4-10 34627953-9 2021 In contrast, the CYP3A4 inducer dexamethasone significantly increased GA metabolism and markedly decreased GA toxicity in mice. Gallium 70-72 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 17-23 34627953-9 2021 In contrast, the CYP3A4 inducer dexamethasone significantly increased GA metabolism and markedly decreased GA toxicity in mice. Gallium 107-109 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 17-23 34627953-10 2021 Notably, in CYP3A4-humanized mice, the toxicity of GA was significantly reduced compared to normal mice. Gallium 51-53 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 12-18 34627953-11 2021 These findings demonstrated that CYP3A4-mediated metabolism is a robust detoxification pathway for GA-induced toxicity. Gallium 99-101 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 33-39 34882929-0 2022 Sly-miR159 regulates fruit morphology by modulating GA biosynthesis in tomato. Gallium 52-54 MIR159 Solanum lycopersicum 4-10 34882929-6 2022 We show the Sly-miR159-SlGAMYB2 pathway controls fruit morphology by modulating GA biosynthesis. Gallium 80-82 MIR159 Solanum lycopersicum 16-22 34882929-7 2022 In particular, we demonstrate that Sly-miR159 promotes GA biosynthesis largely through the direct repression of the GA biosynthetic gene SlGA3ox2 by SlGAMYB2. Gallium 55-57 MIR159 Solanum lycopersicum 39-45 34882929-7 2022 In particular, we demonstrate that Sly-miR159 promotes GA biosynthesis largely through the direct repression of the GA biosynthetic gene SlGA3ox2 by SlGAMYB2. Gallium 116-118 MIR159 Solanum lycopersicum 39-45 34882929-8 2022 Together, our findings reveal the action of Sly-miR159 on GA biosynthesis as a previously unidentified mechanism that controls fruit morphology in tomato. Gallium 58-60 MIR159 Solanum lycopersicum 48-54 34860474-9 2021 There was a significantly higher rate of heterozygous genotypes TC and GA of the VDR gene in group of died patients. Gallium 71-73 vitamin D receptor Homo sapiens 81-84 2393846-3 1990 In the transferrin system, significantly higher transferrin-gallium concentrations were required to achieve the same inhibitory effects. Gallium 60-67 transferrin Homo sapiens 7-18 32796488-1 2020 INTRODUCTION: The authors describe the newly proposed synthesis technique for the gallium-68 (Ga-68)-labeled tracer ([Ga]Ga-PSMA-HBED-CC) for imaging expression of the prostate-specific membrane antigen (PSMA). Gallium 82-89 folate hydrolase 1 Homo sapiens 124-128 32796488-1 2020 INTRODUCTION: The authors describe the newly proposed synthesis technique for the gallium-68 (Ga-68)-labeled tracer ([Ga]Ga-PSMA-HBED-CC) for imaging expression of the prostate-specific membrane antigen (PSMA). Gallium 82-89 folate hydrolase 1 Homo sapiens 168-202 32796488-1 2020 INTRODUCTION: The authors describe the newly proposed synthesis technique for the gallium-68 (Ga-68)-labeled tracer ([Ga]Ga-PSMA-HBED-CC) for imaging expression of the prostate-specific membrane antigen (PSMA). Gallium 82-89 folate hydrolase 1 Homo sapiens 204-208 32796488-1 2020 INTRODUCTION: The authors describe the newly proposed synthesis technique for the gallium-68 (Ga-68)-labeled tracer ([Ga]Ga-PSMA-HBED-CC) for imaging expression of the prostate-specific membrane antigen (PSMA). Gallium 94-96 folate hydrolase 1 Homo sapiens 124-128 32796488-1 2020 INTRODUCTION: The authors describe the newly proposed synthesis technique for the gallium-68 (Ga-68)-labeled tracer ([Ga]Ga-PSMA-HBED-CC) for imaging expression of the prostate-specific membrane antigen (PSMA). Gallium 94-96 folate hydrolase 1 Homo sapiens 168-202 32796488-1 2020 INTRODUCTION: The authors describe the newly proposed synthesis technique for the gallium-68 (Ga-68)-labeled tracer ([Ga]Ga-PSMA-HBED-CC) for imaging expression of the prostate-specific membrane antigen (PSMA). Gallium 94-96 folate hydrolase 1 Homo sapiens 204-208 34893116-7 2021 Western blot showed that Cx43 expression in SP cells was up-regulated when the cells were incubated with MSC, and medium containing 18alpha-GA could partially inhibit it, moreover, it was more significant in MSC cells of MM patients. Gallium 140-142 gap junction protein alpha 1 Homo sapiens 25-29 34893116-15 2021 The levels of IL-6, IL-10 and TGF-beta in supernatant decreased significantly after GJ inhibitor 18alpha-GA was added. Gallium 105-107 interleukin 6 Homo sapiens 14-18 34893116-15 2021 The levels of IL-6, IL-10 and TGF-beta in supernatant decreased significantly after GJ inhibitor 18alpha-GA was added. Gallium 105-107 interleukin 10 Homo sapiens 20-25 34893116-15 2021 The levels of IL-6, IL-10 and TGF-beta in supernatant decreased significantly after GJ inhibitor 18alpha-GA was added. Gallium 105-107 transforming growth factor alpha Homo sapiens 30-38 34885871-0 2021 Preliminary Study of New Gallium-68 Radiolabeled Peptide Targeting NRP-1 to Detect Brain Metastases by Positron Emission Tomography. Gallium 25-32 neuropilin 1 Homo sapiens 67-72 34901598-0 2021 Constructing a Gas Explosion Inversion Model in a Straight Roadway Using the GA-BP Neural Network. Gallium 77-79 gastrin Homo sapiens 15-18 34843261-5 2021 A series of BCMA-targeting nanobodies were produced and two of them were successfully labeled with gallium-68 (68Ga). Gallium 99-106 TNF receptor superfamily member 17 Homo sapiens 12-16 34830843-3 2021 The PSMA uptake on Gallium-68 (68Ga)-PSMA-positron emission tomography/computed tomography (PET/CT) and glucose uptake on F-18-Fluordeoxyglucose (18F-FDG)-PET/CTs were analysed in two ATC and six PDTC patients. Gallium 19-26 folate hydrolase 1 Homo sapiens 4-8 34672630-1 2021 Positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) with gallium-68 (68Ga) and fluorine-18 (18F) radiotracers has aroused tremendous interest over the past few years. Gallium 93-100 folate hydrolase 1 Homo sapiens 46-80 34672630-1 2021 Positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) with gallium-68 (68Ga) and fluorine-18 (18F) radiotracers has aroused tremendous interest over the past few years. Gallium 93-100 folate hydrolase 1 Homo sapiens 82-86 34804079-8 2021 The expression of abscisic acid (ABA) signaling genes (AtABI4 and AtABI5), ABA catabolism genes (AtCYP707A1 and AtCYP707A2), gibberellin acid (GA) catabolism gene (AtGA2ox7), and cytokinin (CTK)-inducible gene (AtARR6) was regulated in the seeds of transgenic lines under cold stress. Gallium 143-145 gibberellin 2-oxidase 7 Arabidopsis thaliana 164-172 34268625-9 2021 The frequent presence of GNAS mutation was a characteristic genetic feature of GEN-FGML (7/34, 20.6%; OGA 1/3, 33.3%; GA-FG 3/24, 12.5%; GA-FGM 3/7, 42.9%) in mutation analysis using next-generation sequencing. Gallium 118-120 GNAS complex locus Homo sapiens 25-29 34542217-5 2021 In contrast we show that the insensitivity of prt6 seeds to ethylene was mainly related to GA signaling disturbance. Gallium 91-93 proteolysis 6 Arabidopsis thaliana 46-50 34611680-3 2021 Similarly, from SbCl3, a cationic formal SbI compound and from RhCl3, (RhI(HMB)(COD))+ and (RhI(COD)2)+ (HMB = C6Me6, COD = 1,5-cyclooctadiene) are formed as (Al(ORF)4)- salts when reacted with Ga+. Gallium 194-197 cortactin binding protein 2 Homo sapiens 158-167 34463604-6 2021 UV-B irradiation affected the expression levels of GA metabolism-related genes (GA20ox1, GA2ox1 and GA3ox1) in the hy5-215 mutant, resulting in increased GA content.ELONGATED HYPOCOTYL 5 (HY5) promoted the accumulation of DELLA proteins under UV-B radiation; HY5 appeared to regulate the abundance of DELLAs at the transcriptional level under UV-B. Gallium 51-53 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 80-87 34463604-6 2021 UV-B irradiation affected the expression levels of GA metabolism-related genes (GA20ox1, GA2ox1 and GA3ox1) in the hy5-215 mutant, resulting in increased GA content.ELONGATED HYPOCOTYL 5 (HY5) promoted the accumulation of DELLA proteins under UV-B radiation; HY5 appeared to regulate the abundance of DELLAs at the transcriptional level under UV-B. Gallium 51-53 gibberellin 2-beta-dioxygenase Arabidopsis thaliana 89-95 34463604-6 2021 UV-B irradiation affected the expression levels of GA metabolism-related genes (GA20ox1, GA2ox1 and GA3ox1) in the hy5-215 mutant, resulting in increased GA content.ELONGATED HYPOCOTYL 5 (HY5) promoted the accumulation of DELLA proteins under UV-B radiation; HY5 appeared to regulate the abundance of DELLAs at the transcriptional level under UV-B. Gallium 51-53 gibberellin 3-oxidase 1 Arabidopsis thaliana 100-106 34476498-1 2021 Gycyrrhizic acid (GA), an inhibitor of high mobility group box 1 (HMGB1), inhibits inflammatory responses and is involved in the occurrence and development of several inflammation-related diseases. Gallium 18-20 high mobility group box 1 Rattus norvegicus 39-64 34476498-1 2021 Gycyrrhizic acid (GA), an inhibitor of high mobility group box 1 (HMGB1), inhibits inflammatory responses and is involved in the occurrence and development of several inflammation-related diseases. Gallium 18-20 high mobility group box 1 Rattus norvegicus 66-71 34476498-14 2021 Furthermore, GA inhibited macrophage activation and decreased alpha-SMA expression in vascular smooth muscle cells, and decreased the expression of proteins (FAS and SREBP-1c) and inflammatory factors. Gallium 13-15 sterol regulatory element binding transcription factor 1 Rattus norvegicus 166-174 34312926-6 2021 In this report, we used a combination of genetic and molecular methods to reveal whether AtRAN1 is involved in both GA- and SA-signaling pathways. Gallium 116-118 copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) Arabidopsis thaliana 89-95 34463555-1 2021 Background Gallium 68 (68Ga) prostate-specific membrane antigen (PSMA) PET/MRI may improve detection of clinically significant prostate cancer (CSPC). Gallium 11-18 folate hydrolase 1 Homo sapiens 29-63 34463555-1 2021 Background Gallium 68 (68Ga) prostate-specific membrane antigen (PSMA) PET/MRI may improve detection of clinically significant prostate cancer (CSPC). Gallium 11-18 folate hydrolase 1 Homo sapiens 65-69 34463555-15 2021 Conclusions Gallium 68 prostate-specific membrane antigen PET/MRI improved specificity for clinically significant prostate cancer compared with multiparametric MRI, particularly in Prostate Imaging Reporting and Data System grade 3 lesions. Gallium 12-19 folate hydrolase 1 Homo sapiens 23-57 34728415-3 2022 Here, we demonstrate that homeobox transcription factor HB40 of the HD-Zip family in Arabidopsis thaliana regulates GA content at two additive control levels. Gallium 116-118 homeobox protein 40 Arabidopsis thaliana 56-60 34728415-4 2022 We show that HB40 expression is induced by GA and in turn reduces the levels of endogenous bioactive GAs by a simultaneous reduction of GA biosynthesis and increased GA deactivation. Gallium 43-45 homeobox protein 40 Arabidopsis thaliana 13-17 34728415-4 2022 We show that HB40 expression is induced by GA and in turn reduces the levels of endogenous bioactive GAs by a simultaneous reduction of GA biosynthesis and increased GA deactivation. Gallium 136-138 homeobox protein 40 Arabidopsis thaliana 13-17 34728415-4 2022 We show that HB40 expression is induced by GA and in turn reduces the levels of endogenous bioactive GAs by a simultaneous reduction of GA biosynthesis and increased GA deactivation. Gallium 166-168 homeobox protein 40 Arabidopsis thaliana 13-17 34728415-8 2022 HB40 also activates genes encoding GA 2-oxidases (GA2oxs) which are major GA catabolic enzymes. Gallium 74-76 homeobox protein 40 Arabidopsis thaliana 0-4 34728415-10 2022 Our results thus uncover an important role of the HB40/JUB1/GA2ox/DELLA regulatory network in controlling GA homeostasis during plant growth. Gallium 106-108 homeobox protein 40 Arabidopsis thaliana 50-54 34728415-10 2022 Our results thus uncover an important role of the HB40/JUB1/GA2ox/DELLA regulatory network in controlling GA homeostasis during plant growth. Gallium 106-108 NAC domain containing protein 42 Arabidopsis thaliana 55-59 34587635-14 2021 The methylation percentage of COX2 was significantly different between LA, RA, and GA groups (14.5 +- 4.1, 13.9 +- 2.8, and 17.0 +- 4.6, respectively, p = 0.012). Gallium 83-85 prostaglandin-endoperoxide synthase 2 Homo sapiens 30-34 34615213-1 2021 We report on the first sub-100 fs mode-locked laser operation of a Tm3+-doped disordered calcium lithium tantalum gallium garnet (Tm:CLTGG) crystal. Gallium 114-121 tropomyosin 3 Homo sapiens 67-70 34552063-6 2021 High mobility group box 1 (HMGB1) secreted by CAFs mediated CAFs" effect on lung cancer cell invasion, demonstrated by using recombinant HMGB1, HMGB1 neutralizing antibody, and HMGB1 inhibitor glycyrrhizin (GA). Gallium 207-209 high mobility group box 1 Mus musculus 0-25 34552063-6 2021 High mobility group box 1 (HMGB1) secreted by CAFs mediated CAFs" effect on lung cancer cell invasion, demonstrated by using recombinant HMGB1, HMGB1 neutralizing antibody, and HMGB1 inhibitor glycyrrhizin (GA). Gallium 207-209 high mobility group box 1 Mus musculus 27-32 34552063-6 2021 High mobility group box 1 (HMGB1) secreted by CAFs mediated CAFs" effect on lung cancer cell invasion, demonstrated by using recombinant HMGB1, HMGB1 neutralizing antibody, and HMGB1 inhibitor glycyrrhizin (GA). Gallium 207-209 high mobility group box 1 Mus musculus 177-182 34374528-7 2021 Taking advantage of the pendant lone pair of the dicoordinated sp2 hybridized N atom, the iminoborane-NHC adduct gives access to NHC-stabilized borenium cation 3 through the reaction with trimethylsilyl triflate (Me3SiOTf) or to the gallium adduct 4 by reacting with GaCl3. Gallium 233-240 Sp2 transcription factor Homo sapiens 63-66 34517439-8 2021 A homozygote mutation in the glutaryl-CoA dehydrogenase gene led to the diagnosis of GA-1. Gallium 85-87 glutaryl-CoA dehydrogenase Homo sapiens 29-55 34302803-8 2021 Moreover, GA reduced the mRNA levels of CCAAT/enhancer binding protein (C/EBP) beta and C/EBPdelta, both of which activate the early stage of adipogenesis. Gallium 10-12 CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus 72-83 34302803-8 2021 Moreover, GA reduced the mRNA levels of CCAAT/enhancer binding protein (C/EBP) beta and C/EBPdelta, both of which activate the early stage of adipogenesis. Gallium 10-12 CCAAT/enhancer binding protein (C/EBP), delta Mus musculus 88-98 34302803-9 2021 Furthermore, GA decreased phosphorylation of extracellular signal-regulated kinase (ERK: p44/42 mitogen-activated protein kinase (MAPK)) in the early stage of adipogenesis. Gallium 13-15 mitogen-activated protein kinase 1 Mus musculus 84-87 34302803-11 2021 These results indicate that GA suppressed the early stage of adipogenesis through repressing the MEK/ERK-mediated C/EBPbeta and C/EBPdelta expression in 3T3-L1 cells. Gallium 28-30 midkine Mus musculus 97-100 34302803-11 2021 These results indicate that GA suppressed the early stage of adipogenesis through repressing the MEK/ERK-mediated C/EBPbeta and C/EBPdelta expression in 3T3-L1 cells. Gallium 28-30 mitogen-activated protein kinase 1 Mus musculus 101-104 34302803-11 2021 These results indicate that GA suppressed the early stage of adipogenesis through repressing the MEK/ERK-mediated C/EBPbeta and C/EBPdelta expression in 3T3-L1 cells. Gallium 28-30 CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus 114-123 34302803-11 2021 These results indicate that GA suppressed the early stage of adipogenesis through repressing the MEK/ERK-mediated C/EBPbeta and C/EBPdelta expression in 3T3-L1 cells. Gallium 28-30 CCAAT/enhancer binding protein (C/EBP), delta Mus musculus 128-138 34832889-2 2021 Numerous different molecules of prostate-specific membrane antigen (PSMA) ligands are used to detect prostate cancer (PCa); most approaches utilize gallium PET and a few reports describe the role of SPECT/CT. Gallium 148-155 folate hydrolase 1 Homo sapiens 32-66 34777194-10 2021 The relative (68Ga)Ga-p14-032 retention in the cortex was stronger in patients with CAA than AD and NC (median SUVr 2.68 +- 1.53 vs. 1.77 +- 0.08 and 0.83 +- 0.24). Gallium 19-21 ribonuclease P/MRP subunit p14 Homo sapiens 22-25 34925811-7 2021 In ISO-induced myocardial infarction, the J-point, heart rate, creatine kinase, lactate dehydrogenase, superoxide dismutase, catalase, malondialdehyde, glutathion, and reactive oxygen species decreased in mice after 18beta-GA treatment. Gallium 222-225 catalase Mus musculus 125-133 34683993-2 2021 Aiming at the fabrication of antibiotic-free biomaterials for antibacterial applications, in this work, we propose the synthesis of gallium (III)-chitosan (Ga (III)-CS) complexes with six different gallium concentrations via an in situ precipitation method. Gallium 132-139 citrate synthase Homo sapiens 165-167 34683993-2 2021 Aiming at the fabrication of antibiotic-free biomaterials for antibacterial applications, in this work, we propose the synthesis of gallium (III)-chitosan (Ga (III)-CS) complexes with six different gallium concentrations via an in situ precipitation method. Gallium 198-205 citrate synthase Homo sapiens 165-167 34648046-1 2022 PURPOSE: We planned this prospective study to evaluate PSMA expression in recurrent high-grade gliomas (rHGG), including anaplastic astrocytoma and glioblastoma using Glu-NH-CO-NH-Lys-(Ahx)-(Ga-68 (HBED-CC))- (Ga-68 PSMA) positron emission tomography (PET), with its theranostic potential in mind. Gallium 210-212 folate hydrolase 1 Homo sapiens 55-59 34643830-2 2021 Different PSMA-analogues labeled with (68Ga)gallium have been investigated, showing excellent imaging properties; however, only small amounts can be produced for each radiolabeling. Gallium 44-51 folate hydrolase 1 Homo sapiens 10-14 34636990-5 2021 RESULTS: The gallium-68 chelator TRAP was utilized to elaborate symmetrical trimers of various peptidic and non-peptidic integrin ligands. Gallium 13-20 TRAP Homo sapiens 33-37 34683912-2 2021 However, a CXCR4-targeting radiopharmaceutical labeled with fluorine-18 is still of high value due to its favorable characteristics over gallium-68. Gallium 137-144 C-X-C motif chemokine receptor 4 Homo sapiens 11-16 34383991-1 2021 The reactivity of the phosphanyl-phosphagallene, (H 2 C{N(Dipp)}) 2 PP=Ga(Nacnac) (Nacnac = HC(C(Me)N(Dipp)) 2 ; Dipp = 2,6- i Pr 2 C 6 H 3 ) towards a series of reagents possessing E-H bonds (primary amines, ammonia, water, phenylacetylene, phenylphosphine, and phenylsilane) is reported. Gallium 71-73 nudix hydrolase 4 Homo sapiens 100-110 34559264-2 2022 METHODS: In this IRB-approved retrospective study, 67 patients (mean age 71 +- 7 years; range: 55-84 years) showing a total of 205 68 Ga-PSMA-positive prostate cancer bone metastases in the thoraco-lumbar spine and pelvic bone being invisible in CT were included. Gallium 134-136 folate hydrolase 1 Homo sapiens 137-141 34491735-8 2021 We selected silver as the solid additive because it rapidly alloys with gallium to form microscale needles that could act as additional paths that aid in connecting the LM droplets. Gallium 72-79 activation induced cytidine deaminase Homo sapiens 147-150 34534693-11 2021 Our results imply that FOXC1 mediates the CSC phenotypes, metastasis, and chemotherapy resistance of GA through Hedgehog and EMT signaling. Gallium 101-103 forkhead box C1 Homo sapiens 23-28 34901958-2 2021 Gallium-68-prostate-specific membrane antigen-11 (68Ga-PSMA-11) targeting PSMA has been at the forefront of imaging in biochemical recurrence however the emergence of fluorine-18 (18F)-PSMA-1007 may prove to be advantageous over the 68Ga-PSMA-11 molecule due to its physical and physiologic al attributes. Gallium 0-7 folate hydrolase 1 Homo sapiens 74-78 34268625-9 2021 The frequent presence of GNAS mutation was a characteristic genetic feature of GEN-FGML (7/34, 20.6%; OGA 1/3, 33.3%; GA-FG 3/24, 12.5%; GA-FGM 3/7, 42.9%) in mutation analysis using next-generation sequencing. Gallium 137-139 GNAS complex locus Homo sapiens 25-29 34575402-3 2021 Promising clinical results sparked the demand for facile production strategies for a functionalized 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-(Thi8, Met(O2)11)-SP to allow for rapid Gallium-68 or Bismuth-213 complexation. Gallium 197-204 SAFB like transcription modulator Homo sapiens 164-167 34135098-6 2021 To further probe the mechanism underlying these differences between opioid inhibition of evoked and spontaneous GABA release, specific myristoylated Ga peptide inhibitors for Gao1 and Gai1-3 that block receptor-G protein interactions were used to test the preference of agonists for MOR-Ga complexes. Gallium 287-289 opioid receptor, mu 1 Mus musculus 283-286 34583984-3 2021 Active CS cases were defined as satisfying at least one of the following criteria for conventional indices: exacerbation of ventricular arrhythmia, newly identified advanced atrioventricular block, greater than 5% decrease in left ventricular ejection fraction on echocardiography, positive finding on gallium-scintigraphy or elevated levels of sarcoidosis-related serum biomarkers. Gallium 302-309 citrate synthase Homo sapiens 7-9 34504491-5 2021 To validate the obtained results, the gene expression of HBD, as the most remarkable DEG in the PBMCS of affected patients, was measured in the PBMCS of healthy donors, treatment-naive MS patients, and MS patients treated with GA, fingolimod, DMF, and IFNbeta-1alpha. Gallium 227-229 HBD Homo sapiens 57-60 34283224-2 2021 Previous studies demonstrated that risdiplam analogues have two separate binding sites in exon 7 of the SMN2 pre-mRNA: (i) the 5"-splice site and (ii) an upstream purine (GA)-rich binding site. Gallium 171-173 survival of motor neuron 2, centromeric Homo sapiens 104-108 34111946-12 2021 Notably, enhancing TET2 enzymatic activity with high-dose ascorbic acid rescued the effect of GA-induced VSMC apoptosis and intimal thickening in a TET2-dependent manner. Gallium 94-96 tet methylcytosine dioxygenase 2 Mus musculus 19-23 34452121-11 2021 In in vitro evaluations, the (68Ga)Ga-RM2 displayed sub-nanomolar affinity (Kd = 0.25 +- 0.19 nM), receptor specific and time dependent membrane-bound fraction of 42.0 +- 5.1% at 60 min and GRP-R mediated internalization of 24.4 +- 4.3% at 30 min. Gallium 35-37 gastrin releasing peptide receptor Homo sapiens 190-195 34359676-12 2021 In vivo activation of GPR17 by GA-T0 reduces the tumor volume, uncovering the potential of GA-T0-GPR17 as a targeted therapy for GBM treatment. Gallium 31-33 G protein-coupled receptor 17 Homo sapiens 22-27 34359676-12 2021 In vivo activation of GPR17 by GA-T0 reduces the tumor volume, uncovering the potential of GA-T0-GPR17 as a targeted therapy for GBM treatment. Gallium 31-33 G protein-coupled receptor 17 Homo sapiens 97-102 34111946-12 2021 Notably, enhancing TET2 enzymatic activity with high-dose ascorbic acid rescued the effect of GA-induced VSMC apoptosis and intimal thickening in a TET2-dependent manner. Gallium 94-96 tet methylcytosine dioxygenase 2 Mus musculus 148-152 34276733-4 2021 Furthermore, cop1, which is known to accumulate DELLA proteins in the dark, shows reduced gibberellin (GA) and JA signaling, thereby phenocopying other DELLA-accumulating mutants. Gallium 103-105 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 13-17 34658547-1 2021 Introduction: We carried out this study to compare the diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) and gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (Ga-68 PSMA PET/CT) to detect prostatic carcinoma in patients with serum prostate-specific antigen (PSA) between 4 and 20 ng/ml in prebiopsy setting. Gallium 133-140 folate hydrolase 1 Homo sapiens 235-239 34182542-14 2021 CONCLUSION: Our findings show that hsa-mir-30a can attenuate the development of GA by down-regulating APBB2 expression. Gallium 80-82 microRNA 30a Homo sapiens 35-46 34182542-14 2021 CONCLUSION: Our findings show that hsa-mir-30a can attenuate the development of GA by down-regulating APBB2 expression. Gallium 80-82 amyloid beta precursor protein binding family B member 2 Homo sapiens 102-107 34203128-1 2021 Cu(In,Ga)Se2 (CIGS) thin films were deposited at low temperature (350 C) and high rate (10 microm/h) by a single stage process. Gallium 6-8 fucosyltransferase 2 Homo sapiens 9-12 34086435-1 2021 Several optoelectronic issues, such as poor optical absorption and recombination, limit the power conversion efficiency of ultrathin Cu(In,Ga)Se2 (CIGS) solar cells. Gallium 139-141 fucosyltransferase 2 Homo sapiens 142-145 34201323-6 2021 To visualize whole-body PD-L1 expression by PET imaging, we developed a nanobody-based radio-immunotracer targeting PD-L1 site-specifically labeled with gallium-68. Gallium 153-160 CD274 molecule Homo sapiens 24-29 34194624-2 2021 GA-binding proteins selectively bind at these positions, respectively, causing an activation of the promoter and overexpression of TERT. Gallium 0-2 telomerase reverse transcriptase Homo sapiens 131-135 34201323-6 2021 To visualize whole-body PD-L1 expression by PET imaging, we developed a nanobody-based radio-immunotracer targeting PD-L1 site-specifically labeled with gallium-68. Gallium 153-160 CD274 molecule Homo sapiens 116-121 34321974-4 2021 This patient, having a lesion that has been enlarged from 2.0 cm to 2.5 cm in 3 months, was referred to our department for restaging by gallium-68 PSMA (68Ga-PSMA) positron emission tomography/computed tomography (PET/CT). Gallium 136-143 folate hydrolase 1 Homo sapiens 147-151 34181329-8 2021 In 2D culture model, Caspase 3 expression and apoptosis was increased significantly in cells of GA exposed group compared to the control group. Gallium 96-98 caspase 3 Homo sapiens 21-30 34108764-1 2021 Objective: To evaluate the effect that external cooling of the salivary glands (ECSG) has on the uptake of gallium-68-labeled prostate-specific membrane antigen (68Ga-PSMA), as an indirect assessment of the capacity of ECSG to reduce the local dose in lutetium-177-PSMA-617 radioligand therapy. Gallium 107-114 folate hydrolase 1 Homo sapiens 167-171 34591387-12 2021 Therefore, MAFG-AS1 might upregulate PLK1 by sponging miR-505 to promote GA cell proliferation. Gallium 73-75 MYC inducible lncRNA inactivating p53 Homo sapiens 11-19 34591387-12 2021 Therefore, MAFG-AS1 might upregulate PLK1 by sponging miR-505 to promote GA cell proliferation. Gallium 73-75 polo like kinase 1 Homo sapiens 37-41 34591387-12 2021 Therefore, MAFG-AS1 might upregulate PLK1 by sponging miR-505 to promote GA cell proliferation. Gallium 73-75 microRNA 505 Homo sapiens 54-61 34155432-3 2021 The complexes (M(GA)2(H2O)2), where (M = Mn(II), Co(II), and Ni(II)) form octahedral structures, while (M(GA)2) complexes (M = Zn(II), Cd(II), and Hg(II)) display four-coordination geometry. Gallium 17-20 mitochondrially encoded cytochrome c oxidase II Homo sapiens 49-55 35620858-7 2022 The FT-IR study indicated that the GaOOH-rich gallium surface produced Ga3+ and OH- ions. Gallium 46-53 succinyl-CoA:glutarate-CoA transferase Homo sapiens 71-74 35166426-9 2022 On multivariable logistic regression analysis, the intraprostatic SUVmax was an independent predictor of pN1 for both 68 Ga-PSMA-11 (per doubling: odds ratio (OR) 1.96 (95% Confidence Interval (CI) 1.27-3.01)) and 18 F-PSMA (per doubling: OR 1.79 (95%CI 1.06-3.03). Gallium 121-123 serpin family E member 2 Homo sapiens 105-108 35166426-9 2022 On multivariable logistic regression analysis, the intraprostatic SUVmax was an independent predictor of pN1 for both 68 Ga-PSMA-11 (per doubling: odds ratio (OR) 1.96 (95% Confidence Interval (CI) 1.27-3.01)) and 18 F-PSMA (per doubling: OR 1.79 (95%CI 1.06-3.03). Gallium 121-123 folate hydrolase 1 Homo sapiens 124-128 35166426-9 2022 On multivariable logistic regression analysis, the intraprostatic SUVmax was an independent predictor of pN1 for both 68 Ga-PSMA-11 (per doubling: odds ratio (OR) 1.96 (95% Confidence Interval (CI) 1.27-3.01)) and 18 F-PSMA (per doubling: OR 1.79 (95%CI 1.06-3.03). Gallium 121-123 folate hydrolase 1 Homo sapiens 219-223 35605991-10 2022 Furthermore, the ProCCK peptides exhibit dose dependent Ga subtype selectivity in that they faciliate coupling to Gas at low concentrations and Gai at high concentrations. Gallium 56-58 gastrin Mus musculus 114-117 35588269-1 2022 A key requisite to characterizing GaN precipitation from ammonia solution from molecular simulations is the availability of reliable molecular mechanics models for the interactions of gallium ions with NH3 , NH2 - , and NH2- species, respectively. Gallium 184-191 gigaxonin Homo sapiens 34-37 35584444-1 2022 OBJECTIVE: To evaluate the predictive value of positron emission computed tomography or magnetic resonance (PET-CT and PET-MRI) using gallium-68-labeled prostate-specific membrane antigen (68Ga-PSMA) in lymph node involvement in prostate cancer. Gallium 134-141 folate hydrolase 1 Homo sapiens 153-198 35546785-5 2022 The cGAS rs610913 CA+AA had significant interaction effects with STING rs11554776 GG+GA (P = 0.035), rs7380824 CC+CT (P = 0.026), and rs78233829 GC+CC (P = 0.034) on mtDNAcn. Gallium 85-87 stimulator of interferon response cGAMP interactor 1 Homo sapiens 65-70 34585093-1 2021 Objectives: The loss of function of the E-cadherin (CDH1) gene with -160 C A and -347 G GA polymorphisms is regarded as a critical step for gastric cancer. Gallium 88-90 cadherin 1 Homo sapiens 40-50 34585093-1 2021 Objectives: The loss of function of the E-cadherin (CDH1) gene with -160 C A and -347 G GA polymorphisms is regarded as a critical step for gastric cancer. Gallium 88-90 cadherin 1 Homo sapiens 52-56 35342454-4 2022 GA directly decreases SARS-CoV-2 viral replication and intrinsically down-regulates NFkappaB pathway therefore significantly inhibiting expression of inflammatory cytokines in cells. Gallium 0-2 nuclear factor kappa B subunit 1 Homo sapiens 84-92 35633059-10 2022 Moreover, inhibited SUMOylation by GA (E1 inhibitor) or 2-D08 (UBC9 inhibitor) can increase the spinal surface Kir7.1 expression. Gallium 35-37 potassium inwardly-rectifying channel, subfamily J, member 13 Rattus norvegicus 111-117 35613428-1 2022 Gallium (Ga) compounds, as the source of Ga ions (Ga3+), have been historically used as anti-inflammatories. Gallium 0-7 succinyl-CoA:glutarate-CoA transferase Homo sapiens 50-53 35613428-1 2022 Gallium (Ga) compounds, as the source of Ga ions (Ga3+), have been historically used as anti-inflammatories. Gallium 9-11 succinyl-CoA:glutarate-CoA transferase Homo sapiens 50-53 35613428-1 2022 Gallium (Ga) compounds, as the source of Ga ions (Ga3+), have been historically used as anti-inflammatories. Gallium 41-43 succinyl-CoA:glutarate-CoA transferase Homo sapiens 50-53 35610039-1 2022 Objectives: Gallium-68 (68Ga) Pentixafor PET/CT imaging allows non-invasive assessment of CXCR4 expression in various malignancies, but its use in rare lung cancer variants is not reported. Gallium 12-19 C-X-C motif chemokine receptor 4 Homo sapiens 90-95 35510594-2 2022 The reaction of 1 and 2 with 1,2,3,4-tetramethylimidazolin-2-ylidene, IMe4, gave rise to the formation of (2,6-Mes2C6H3)2EP(O)C(IMe4) (3, E = Ga; 4 E = In; Mes = mesityl). Gallium 142-144 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 70-74 35510594-2 2022 The reaction of 1 and 2 with 1,2,3,4-tetramethylimidazolin-2-ylidene, IMe4, gave rise to the formation of (2,6-Mes2C6H3)2EP(O)C(IMe4) (3, E = Ga; 4 E = In; Mes = mesityl). Gallium 142-144 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 128-132 35510594-3 2022 Subsequent addition of elemental tellurium proceeded via insertion into the E-P bond and provided (2,6-Mes2C6H3)2ETeP(O)C(IMe4) (5, E = Ga; 6, E = In) comprising five-membered ETePCO-heterocycles. Gallium 136-138 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 122-126 35491036-3 2022 By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite. Gallium 228-230 alkaline phosphatase, placental Homo sapiens 103-123 35491036-3 2022 By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite. Gallium 228-230 alkaline phosphatase, placental Homo sapiens 125-128 35491036-5 2022 However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite. Gallium 161-163 alkaline phosphatase, placental Homo sapiens 43-46 35491036-5 2022 However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite. Gallium 169-171 alkaline phosphatase, placental Homo sapiens 43-46 34321974-4 2021 This patient, having a lesion that has been enlarged from 2.0 cm to 2.5 cm in 3 months, was referred to our department for restaging by gallium-68 PSMA (68Ga-PSMA) positron emission tomography/computed tomography (PET/CT). Gallium 136-143 folate hydrolase 1 Homo sapiens 153-162 35564180-6 2022 In an in silico molecular docking study of the gallium-curcumin complex in PDI, calnexin, HSP60, PDK, caspase 9, Akt1 and PTEN were found to be strong binding. Gallium 47-54 prolyl 4-hydroxylase subunit beta Homo sapiens 75-78 35191735-2 2022 Gallium 68 (68Ga) prostate-specific membrane antigen (PSMA) PET/CT-guided targeted biopsy has the potential to improve diagnostic yield of PCa. Gallium 0-7 folate hydrolase 1 Homo sapiens 18-52 35191735-2 2022 Gallium 68 (68Ga) prostate-specific membrane antigen (PSMA) PET/CT-guided targeted biopsy has the potential to improve diagnostic yield of PCa. Gallium 0-7 folate hydrolase 1 Homo sapiens 54-58 35564180-6 2022 In an in silico molecular docking study of the gallium-curcumin complex in PDI, calnexin, HSP60, PDK, caspase 9, Akt1 and PTEN were found to be strong binding. Gallium 47-54 calnexin Homo sapiens 80-88 35564180-6 2022 In an in silico molecular docking study of the gallium-curcumin complex in PDI, calnexin, HSP60, PDK, caspase 9, Akt1 and PTEN were found to be strong binding. Gallium 47-54 heat shock protein family D (Hsp60) member 1 Homo sapiens 90-95 35564180-6 2022 In an in silico molecular docking study of the gallium-curcumin complex in PDI, calnexin, HSP60, PDK, caspase 9, Akt1 and PTEN were found to be strong binding. Gallium 47-54 caspase 9 Homo sapiens 102-111 35564180-6 2022 In an in silico molecular docking study of the gallium-curcumin complex in PDI, calnexin, HSP60, PDK, caspase 9, Akt1 and PTEN were found to be strong binding. Gallium 47-54 AKT serine/threonine kinase 1 Homo sapiens 113-117 35564180-6 2022 In an in silico molecular docking study of the gallium-curcumin complex in PDI, calnexin, HSP60, PDK, caspase 9, Akt1 and PTEN were found to be strong binding. Gallium 47-54 phosphatase and tensin homolog Homo sapiens 122-126 35564180-9 2022 The mechanism of gallium-mediated apoptosis was analyzed through western blotting and GaC-HMSNAP has increased caspases 9, 6, cleaved caspase 6, PARP, and GSK 3beta(S9) in MCF-7 cells. Gallium 17-24 caspase 6 Homo sapiens 134-143 35564180-9 2022 The mechanism of gallium-mediated apoptosis was analyzed through western blotting and GaC-HMSNAP has increased caspases 9, 6, cleaved caspase 6, PARP, and GSK 3beta(S9) in MCF-7 cells. Gallium 17-24 poly(ADP-ribose) polymerase 1 Homo sapiens 145-149 35564180-9 2022 The mechanism of gallium-mediated apoptosis was analyzed through western blotting and GaC-HMSNAP has increased caspases 9, 6, cleaved caspase 6, PARP, and GSK 3beta(S9) in MCF-7 cells. Gallium 17-24 glycogen synthase kinase 3 alpha Homo sapiens 155-164 35426551-6 2022 The expression level of GA response gene expansin8 (EXP8) was lower in transgenic ZjGRF1 Arabidopsis than in WT. Gallium 24-26 expansin A8 Arabidopsis thaliana 41-50 35426551-6 2022 The expression level of GA response gene expansin8 (EXP8) was lower in transgenic ZjGRF1 Arabidopsis than in WT. Gallium 24-26 expansin A8 Arabidopsis thaliana 52-56 35078860-8 2022 (68Ga)Ga-BL02 uptake correlated with CXCR4 expression, and localized lesions in a metastatic xenograft model. Gallium 6-8 C-X-C motif chemokine receptor 4 Homo sapiens 37-42 35458044-6 2022 Due to the formation of a gallium-aluminum amalgam, the Al-air battery had the best discharge characteristics in the electrolyte with 0.2 M Ga3+, and its discharge voltage reached 0.9734 V with a remarkable increase compared with that of NaCl solution (0.4228 V). Gallium 26-33 succinyl-CoA:glutarate-CoA transferase Homo sapiens 140-143 35435234-6 2022 ARF7 directly binds to the promoter region of the cambial stem cell regulator WOX4 to modulate its expression, thus integrating auxin and GA signaling to regulate cambial activity. Gallium 138-140 ADP ribosylation factor like GTPase 14 Homo sapiens 0-4 35085799-6 2022 Conversely, culturing of pro-inflammatory activated primary murine macrophages in HA-GA gels resulted in a significant reduction of pro-inflammatory TNF-alpha, IL-1beta, SOCS3 and IL-6 marker expression, and upregulated expression of anti-inflammatory cytokines including TGF-beta. Gallium 85-87 transforming growth factor alpha Mus musculus 272-280 35435234-7 2022 Furthermore, the direct activation of PIN-FORMED 1 (PIN1) expression by ARF7 in the RGL1-ARF7-IAA9 module increased GA-dependent cambial activity via polar auxin transport. Gallium 116-118 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 38-50 35435234-7 2022 Furthermore, the direct activation of PIN-FORMED 1 (PIN1) expression by ARF7 in the RGL1-ARF7-IAA9 module increased GA-dependent cambial activity via polar auxin transport. Gallium 116-118 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 52-56 35435234-7 2022 Furthermore, the direct activation of PIN-FORMED 1 (PIN1) expression by ARF7 in the RGL1-ARF7-IAA9 module increased GA-dependent cambial activity via polar auxin transport. Gallium 116-118 ADP ribosylation factor like GTPase 14 Homo sapiens 72-76 35435234-7 2022 Furthermore, the direct activation of PIN-FORMED 1 (PIN1) expression by ARF7 in the RGL1-ARF7-IAA9 module increased GA-dependent cambial activity via polar auxin transport. Gallium 116-118 ral guanine nucleotide dissociation stimulator like 1 Homo sapiens 84-88 35435234-7 2022 Furthermore, the direct activation of PIN-FORMED 1 (PIN1) expression by ARF7 in the RGL1-ARF7-IAA9 module increased GA-dependent cambial activity via polar auxin transport. Gallium 116-118 ADP ribosylation factor like GTPase 14 Homo sapiens 89-93 35435234-8 2022 Collectively, these findings reveal that the crosstalk between auxin and GA signaling mediated by the RGL1-ARF7-IAA9 module is crucial for the precise regulation of cambial development in poplar. Gallium 73-75 ral guanine nucleotide dissociation stimulator like 1 Homo sapiens 102-106 35435234-8 2022 Collectively, these findings reveal that the crosstalk between auxin and GA signaling mediated by the RGL1-ARF7-IAA9 module is crucial for the precise regulation of cambial development in poplar. Gallium 73-75 ADP ribosylation factor like GTPase 14 Homo sapiens 107-111 35393708-8 2022 Taken all together, this study revealed that grafting GA onto the chitosan improved potential anti-adipogenic activity by induction of the HO-1/Nrf2 pathway on mesenchymal stem cells (MSCs). Gallium 54-56 heme oxygenase 1 Homo sapiens 139-143 35393708-8 2022 Taken all together, this study revealed that grafting GA onto the chitosan improved potential anti-adipogenic activity by induction of the HO-1/Nrf2 pathway on mesenchymal stem cells (MSCs). Gallium 54-56 NFE2 like bZIP transcription factor 2 Homo sapiens 144-148 35085799-5 2022 The THP-1 human macrophage cell line or primary bone-marrow-derived murine macrophages cultured within HA-GA gels displayed selective polarization to a predominantly anti-inflammatory phenotype by upregulating IL4ra, IL-10, TGF-beta, and TGF-betaR1 expression when compared with HA-HA gels. Gallium 106-108 interleukin 4 receptor, alpha Mus musculus 210-215 35085799-5 2022 The THP-1 human macrophage cell line or primary bone-marrow-derived murine macrophages cultured within HA-GA gels displayed selective polarization to a predominantly anti-inflammatory phenotype by upregulating IL4ra, IL-10, TGF-beta, and TGF-betaR1 expression when compared with HA-HA gels. Gallium 106-108 interleukin 10 Mus musculus 217-222 35085799-5 2022 The THP-1 human macrophage cell line or primary bone-marrow-derived murine macrophages cultured within HA-GA gels displayed selective polarization to a predominantly anti-inflammatory phenotype by upregulating IL4ra, IL-10, TGF-beta, and TGF-betaR1 expression when compared with HA-HA gels. Gallium 106-108 transforming growth factor alpha Mus musculus 224-232 35085799-6 2022 Conversely, culturing of pro-inflammatory activated primary murine macrophages in HA-GA gels resulted in a significant reduction of pro-inflammatory TNF-alpha, IL-1beta, SOCS3 and IL-6 marker expression, and upregulated expression of anti-inflammatory cytokines including TGF-beta. Gallium 85-87 tumor necrosis factor Mus musculus 149-158 35085799-6 2022 Conversely, culturing of pro-inflammatory activated primary murine macrophages in HA-GA gels resulted in a significant reduction of pro-inflammatory TNF-alpha, IL-1beta, SOCS3 and IL-6 marker expression, and upregulated expression of anti-inflammatory cytokines including TGF-beta. Gallium 85-87 interleukin 1 alpha Mus musculus 160-168 35085799-6 2022 Conversely, culturing of pro-inflammatory activated primary murine macrophages in HA-GA gels resulted in a significant reduction of pro-inflammatory TNF-alpha, IL-1beta, SOCS3 and IL-6 marker expression, and upregulated expression of anti-inflammatory cytokines including TGF-beta. Gallium 85-87 suppressor of cytokine signaling 3 Mus musculus 170-175 35085799-6 2022 Conversely, culturing of pro-inflammatory activated primary murine macrophages in HA-GA gels resulted in a significant reduction of pro-inflammatory TNF-alpha, IL-1beta, SOCS3 and IL-6 marker expression, and upregulated expression of anti-inflammatory cytokines including TGF-beta. Gallium 85-87 interleukin 6 Mus musculus 180-184 35202920-3 2022 Temperature dependencies of apparent standard redox potentials of La(Ga), Pr(Ga) and U(Ga) alloys were determined by open-circuit chronopotentiometry versus Cl-/Cl2 reference electrode. Gallium 69-71 plasminogen like A (pseudogene) Homo sapiens 74-90 35432433-5 2022 35S::OnACS12 repressed GA biosynthesis genes (CPS, KS, and GA3ox1), which caused the upregulation of DELLA (GA-INSENSITIVE (GAI), RGA-LIKE1 (RGL1), and RGL2) expression. Gallium 23-25 gibberellin 3-oxidase 1 Arabidopsis thaliana 59-65 35432433-5 2022 35S::OnACS12 repressed GA biosynthesis genes (CPS, KS, and GA3ox1), which caused the upregulation of DELLA (GA-INSENSITIVE (GAI), RGA-LIKE1 (RGL1), and RGL2) expression. Gallium 23-25 RGA-like 1 Arabidopsis thaliana 130-139 35432433-5 2022 35S::OnACS12 repressed GA biosynthesis genes (CPS, KS, and GA3ox1), which caused the upregulation of DELLA (GA-INSENSITIVE (GAI), RGA-LIKE1 (RGL1), and RGL2) expression. Gallium 23-25 RGA-like 1 Arabidopsis thaliana 141-145 35432433-5 2022 35S::OnACS12 repressed GA biosynthesis genes (CPS, KS, and GA3ox1), which caused the upregulation of DELLA (GA-INSENSITIVE (GAI), RGA-LIKE1 (RGL1), and RGL2) expression. Gallium 23-25 RGA-like 2 Arabidopsis thaliana 152-156 35432433-10 2022 These results not only provide new insight into the functions of ACS and ETR1 orthologs but also uncover their functional interactions with other hormone signaling pathways, such as GA-DELLA and JA, in plants. Gallium 182-184 acetyl-CoA synthetase Arabidopsis thaliana 65-68 35432433-10 2022 These results not only provide new insight into the functions of ACS and ETR1 orthologs but also uncover their functional interactions with other hormone signaling pathways, such as GA-DELLA and JA, in plants. Gallium 182-184 Signal transduction histidine kinase, hybrid-type, ethylene sensor Arabidopsis thaliana 73-77 35148416-2 2022 In addition, BRs can also activate GA catabolism; here we show that in Arabidopsis (Arabidopsis thaliana) the bHLH transcription factor CESTA (CES) and its homologues BRASSINOSTEROID ENHANCED EXPRESSION (BEE) 1 and 3 contribute to this activity. Gallium 35-37 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 136-141 35148416-2 2022 In addition, BRs can also activate GA catabolism; here we show that in Arabidopsis (Arabidopsis thaliana) the bHLH transcription factor CESTA (CES) and its homologues BRASSINOSTEROID ENHANCED EXPRESSION (BEE) 1 and 3 contribute to this activity. Gallium 35-37 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 143-146 35148416-2 2022 In addition, BRs can also activate GA catabolism; here we show that in Arabidopsis (Arabidopsis thaliana) the bHLH transcription factor CESTA (CES) and its homologues BRASSINOSTEROID ENHANCED EXPRESSION (BEE) 1 and 3 contribute to this activity. Gallium 35-37 BR enhanced expression 1 Arabidopsis thaliana 167-216 35148416-6 2022 In plants that over-express CES, GA2ox7 expression is hyper-responsive to BR, GA110 levels are elevated and amounts of bioactive GA are reduced. Gallium 129-131 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 28-31 35148416-6 2022 In plants that over-express CES, GA2ox7 expression is hyper-responsive to BR, GA110 levels are elevated and amounts of bioactive GA are reduced. Gallium 129-131 gibberellin 2-oxidase 7 Arabidopsis thaliana 33-39 35332238-3 2022 In addition to transporting GLSs, AtGTR1 also transports phytohormones, jasmonic acid-isoleucine (JA-Ile), and gibberellin (GA). Gallium 124-126 Major facilitator superfamily protein Arabidopsis thaliana 34-40 35329561-7 2022 On the other hand, the addition of GP with the mean size of 28.3 and 47.9 mum can effectively mitigate the ASR expansion of GA mortars. Gallium 124-126 gp Drosophila melanogaster 35-37 35399427-4 2022 In December 2020, FDA approved Gallium-68 (68Ga) PSMA, which is a PSMA-targeted positron emission tomography (PET) imaging agent. Gallium 31-38 folate hydrolase 1 Homo sapiens 49-53 35399427-4 2022 In December 2020, FDA approved Gallium-68 (68Ga) PSMA, which is a PSMA-targeted positron emission tomography (PET) imaging agent. Gallium 31-38 folate hydrolase 1 Homo sapiens 66-70 35229224-3 2022 This study primarily aimed to compare the diagnostic performance of fluoride PET/CT and gallium-based PSMA PET/CT in identifying bone metastasis followed by a comparison of PSMA PET/CT with contrast-enhanced CT (CE-CT) in identifying soft tissue lesions as a secondary objective. Gallium 88-95 folate hydrolase 1 Homo sapiens 102-106 35147029-4 2022 The lateral synaptic diode is based on a p-n junction of an organic semiconductor (OSC) and amorphous In-Ga-Zn-O, in which the upper OSC layer can directly interact with the gas molecules in the atmosphere. Gallium 105-107 gastrin Homo sapiens 174-177 35218431-5 2022 Glucose was specifically captured by glucose oxidase (GOx) which were immobilized into the GA@PB by chitosan. Gallium 91-93 hydroxyacid oxidase 1 Homo sapiens 37-52 35218431-5 2022 Glucose was specifically captured by glucose oxidase (GOx) which were immobilized into the GA@PB by chitosan. Gallium 91-93 hydroxyacid oxidase 1 Homo sapiens 54-57 35133137-11 2022 Ga implantation of the surface also resulted in reduced foreign body giant cell formation and expression of proinflammatory cytokine IL-1beta. Gallium 0-2 interleukin 1 alpha Homo sapiens 133-141 35166830-2 2022 A major mechanism by which GA promotes seed germination is by promoting the degradation of the DELLA protein RGL2 (RGA-LIKE2), a major repressor of germination in Arabidopsis (Arabidopsis thaliana) seeds. Gallium 27-29 RGA-like 2 Arabidopsis thaliana 109-113 35166830-2 2022 A major mechanism by which GA promotes seed germination is by promoting the degradation of the DELLA protein RGL2 (RGA-LIKE2), a major repressor of germination in Arabidopsis (Arabidopsis thaliana) seeds. Gallium 27-29 RGA-like 2 Arabidopsis thaliana 115-124 35166830-3 2022 Analysis of seed germination phenotypes of constitutively photomorphogenic1 (cop1) mutants and complemented COP1-OX/cop1-4 lines in response to GA and paclobutrazol (PAC) suggested a positive role for COP1 in seed germination and a relation with GA signaling. Gallium 144-146 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 43-75 35166830-3 2022 Analysis of seed germination phenotypes of constitutively photomorphogenic1 (cop1) mutants and complemented COP1-OX/cop1-4 lines in response to GA and paclobutrazol (PAC) suggested a positive role for COP1 in seed germination and a relation with GA signaling. Gallium 144-146 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 77-81 35166830-3 2022 Analysis of seed germination phenotypes of constitutively photomorphogenic1 (cop1) mutants and complemented COP1-OX/cop1-4 lines in response to GA and paclobutrazol (PAC) suggested a positive role for COP1 in seed germination and a relation with GA signaling. Gallium 144-146 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 116-120 35166830-3 2022 Analysis of seed germination phenotypes of constitutively photomorphogenic1 (cop1) mutants and complemented COP1-OX/cop1-4 lines in response to GA and paclobutrazol (PAC) suggested a positive role for COP1 in seed germination and a relation with GA signaling. Gallium 144-146 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 201-205 35166830-8 2022 Moreover, GA stabilized COP1 with consequent RGL2 destabilization. Gallium 10-12 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 24-28 35166830-8 2022 Moreover, GA stabilized COP1 with consequent RGL2 destabilization. Gallium 10-12 RGA-like 2 Arabidopsis thaliana 45-49 35216125-3 2022 The exogenous application of GA considerably exacerbated the defects in mac5a null mutants, including fewer stamens and male sterility. Gallium 29-31 CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Arabidopsis thaliana 72-77 35147737-6 2022 A novel GPC3-specific single domain antibody (sdAb) was produced and labeled with gallium-68 (68Ga, T1/2 = 1.1 h) and fluorine-18 (18F, T1/2 = 1.8 h) to develop radiotracers with different half-lives. Gallium 82-89 glypican 3 Homo sapiens 8-12 35214831-1 2022 The interaction between cytokinin, auxin and GA controlled in vitro shoot multiplication in paulownia was influenced by a medium water potential (Psi) modulation, where it was modulated using different textures or strengths of MS medium, media of different types (MS, WPM, SH and B5) or NaCl incorporation. Gallium 45-47 glycoprotein hormone subunit beta 5 Homo sapiens 273-282 35164214-5 2022 The main objective of this study was to identify a new potential neuraminidase inhibitor from GA. Gallium 94-96 neuraminidase 1 Homo sapiens 65-78 35581072-4 2022 Substitution of both zinc and gallium in the structure of HAp results in a gradual decrease in the lattice parameters as doping level increases, limits the growth of HAp particles and reduces its crystallinity. Gallium 30-37 hemaglutinin-associated protein Escherichia coli 58-61 35581072-4 2022 Substitution of both zinc and gallium in the structure of HAp results in a gradual decrease in the lattice parameters as doping level increases, limits the growth of HAp particles and reduces its crystallinity. Gallium 30-37 hemaglutinin-associated protein Escherichia coli 166-169 35581072-6 2022 Ion doping also significantly modulate the release of bioactive ions (Ca2+, PO43-, Zn2+, Ga3+) from the Zn-Ga:HAp depended on the overall amount of Ga and Zn in the HAp, which could mediate the biological responses. Gallium 107-109 hemaglutinin-associated protein Escherichia coli 110-113 35581072-6 2022 Ion doping also significantly modulate the release of bioactive ions (Ca2+, PO43-, Zn2+, Ga3+) from the Zn-Ga:HAp depended on the overall amount of Ga and Zn in the HAp, which could mediate the biological responses. Gallium 107-109 hemaglutinin-associated protein Escherichia coli 165-168 35581072-6 2022 Ion doping also significantly modulate the release of bioactive ions (Ca2+, PO43-, Zn2+, Ga3+) from the Zn-Ga:HAp depended on the overall amount of Ga and Zn in the HAp, which could mediate the biological responses. Gallium 148-150 hemaglutinin-associated protein Escherichia coli 110-113 34758118-8 2022 Furthermore, MYC1 and MYC2 transcriptionally regulate the GA signalling suppressor DELLA that by itself interferes in JA-mediated SGA control by modulating MYC activity through protein-protein interaction. Gallium 58-60 transcription factor MYC1 Solanum lycopersicum 13-17 34758118-8 2022 Furthermore, MYC1 and MYC2 transcriptionally regulate the GA signalling suppressor DELLA that by itself interferes in JA-mediated SGA control by modulating MYC activity through protein-protein interaction. Gallium 58-60 transcription factor MYC2 Solanum lycopersicum 22-26 35104992-3 2022 This paper presents the development and the first neutron imaging results of a neutron flat-panel detector (nFPD) based on an In-Ga-Zn-O (IGZO) thin-film transistor (TFT)/photodiode array coupled with a LiF/ZnS scintillator sheet. Gallium 129-131 LIF interleukin 6 family cytokine Homo sapiens 203-206 35098042-1 2022 Ag alloying and the introduction of alkali elements through a postdeposition treatment are two approaches to improve the performance of Cu(In,Ga)Se2 (CIGS) thin film solar cells. Gallium 142-144 fucosyltransferase 2 Homo sapiens 145-148 35158819-2 2022 Here, we examined the Kras gene status in a cohort of unresectable PDAC patients who underwent first-line therapy with gemcitabine and nab-paclitaxel (GA) and assessed differences in chemotherapy responses and survival. Gallium 151-153 KRAS proto-oncogene, GTPase Homo sapiens 22-26 35096836-0 2021 HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS. Gallium 27-29 histone deacetylase 6 Mus musculus 0-5 2743310-1 1989 In previous studies, we have demonstrated that transferrin-gallium inhibits cellular proliferation by a mechanism whereby cellular iron utilization is impaired. Gallium 59-66 transferrin Homo sapiens 47-58 2796048-3 1989 There was a statistically significant difference in the FN content of BALF between patients with higher and those with lower uptake of Ga into the lung field. Gallium 135-137 fibronectin 1 Homo sapiens 56-58 2752150-0 1989 Effect of transferrin-gallium on leukemic cells. Gallium 22-29 transferrin Homo sapiens 10-21 2743310-4 1989 Cells exposed to relatively low concentrations of transferrin-indium exhibit markedly increased transferrin receptor expression but, as with transferrin-gallium, these cells incorporate an inappropriately low amount of iron, suggesting that there is a defect in the release of internalized iron from transferrin. Gallium 153-160 transferrin Homo sapiens 50-61 2785514-0 1989 Gallium-68-labeled macroaggregated human serum albumin, 68Ga-MAA. Gallium 0-7 albumin Homo sapiens 41-54 2714421-0 1989 Transferrin receptor-mediated suppression of in vitro hematopoiesis by transferrin-gallium. Gallium 83-90 transferrin Homo sapiens 0-11 2714421-0 1989 Transferrin receptor-mediated suppression of in vitro hematopoiesis by transferrin-gallium. Gallium 83-90 transferrin Homo sapiens 71-82 2714421-2 1989 We have recently shown that transferrin-gallium (Tf-Ga) complexes bind to cellular transferrin receptors and inhibit cellular iron incorporation. Gallium 40-47 transferrin Homo sapiens 28-39 2714421-2 1989 We have recently shown that transferrin-gallium (Tf-Ga) complexes bind to cellular transferrin receptors and inhibit cellular iron incorporation. Gallium 40-47 transferrin Homo sapiens 83-94 2537143-0 1989 Modulation of lymphocyte proliferation and immunoglobulin production by transferrin-gallium. Gallium 84-91 transferrin Homo sapiens 72-83 2537143-1 1989 Gallium resembles iron with respect to transferrin (Tf) binding and cellular uptake via Tf receptors. Gallium 0-7 transferrin Homo sapiens 39-50 2537143-2 1989 We have previously shown that transferrin-gallium (Tf-Ga) complexes interfere with the cellular incorporation of iron and inhibit the proliferation of HL60 cells. Gallium 42-49 transferrin Homo sapiens 30-41 3058232-2 1988 We have previously shown that transferrin-gallium (Tf-Ga) inhibits cellular iron incorporation. Gallium 42-49 transferrin Homo sapiens 30-41 2536083-0 1989 Role of phosphate-containing compounds in the transfer of indium-111 and gallium-67 from transferrin to ferritin. Gallium 73-80 transferrin Homo sapiens 89-100 3048831-3 1988 The cases are examined in light of published data demonstrating such factors as transferrin levels, radiation, and chemotherapeutic agents as altering the hepatic uptake of gallium. Gallium 173-180 transferrin Homo sapiens 80-91 3259158-9 1988 Gallium did not significantly alter the capacity of permeabilized naive cells to incorporate [3H]dTTP into DNA, while 24-h gallium pretreatment (which increased the percentage of S-phase cells) produced a modest increase in [3H]dTTP incorporation, indicating that any effect of gallium on DNA polymerase alpha is minor. Gallium 123-130 DNA polymerase alpha 1, catalytic subunit Homo sapiens 289-309 3275103-1 1988 Gallium scintigraphy was performed as an aid for determining the presence or absence of malignant neoplasm in two patients with hemochromatosis treated by deferoxamine. Gallium 0-7 activation induced cytidine deaminase Homo sapiens 41-44 3341221-6 1988 The erythrocyte sedimentation rate and C-reactive protein level were both higher in patients with Ga-67 uptake compared with those with a negative scan result (p less than 0.01 in both). Gallium 98-100 C-reactive protein Homo sapiens 39-57 3422092-2 1988 A possible mechanism for this incidental finding is elevated prolactin levels, as other causes of gallium breast uptake such as drug therapy, and intrinsic breast disease, were not present. Gallium 98-105 prolactin Homo sapiens 61-70 3341032-13 1988 The concentration of gallium required to achieve half-maximal inhibition of ALAD in vitro was 200-fold less in blood and 40-fold less in kidney and liver than that required for arsenite and the inhibition was partially prevented by excess zinc. Gallium 21-28 aminolevulinate dehydratase Rattus norvegicus 76-80 3341032-14 1988 These data suggest that gallium is the primary inhibitor of ALAD following dissolution of GaAs in vivo and that competition for or displacement of zinc from the enzyme active site may be involved in the mechanism of inhibition. Gallium 24-31 aminolevulinate dehydratase Rattus norvegicus 60-64 3266964-0 1988 Gallium-transferrin as a macromolecular tracer of vascular permeability. Gallium 0-7 transferrin Rattus norvegicus 8-19 3266964-1 1988 Labeling of plasma transferrin with gallium was investigated to determine whether the gallium-transferrin complex could be effectively used as a macromolecular tracer in studies of capillary permeability using Positron Emission Tomography (PET). Gallium 36-43 transferrin Rattus norvegicus 19-30 3266964-3 1988 The three preparations gave similar blood clearance and tissue distribution data, but the methods used for evaluating gallium-transferrin binding were found to be suboptimal. Gallium 118-125 transferrin Rattus norvegicus 126-137 3448322-0 1987 [Evaluation of in vivo stability of Ga-67 labeled human fibrinogen; analysis of plasma radioactivity using rats]. Gallium 36-38 fibrinogen beta chain Homo sapiens 56-66 3438486-0 1987 Clinical applications of Ga-67 DFO-DAS-fibrinogen. Gallium 25-27 fibrinogen beta chain Homo sapiens 39-49 3438488-0 1987 Clinical use of Ga-67 DFO-DAS-fibrinogen. Gallium 16-18 fibrinogen beta chain Homo sapiens 30-40 3475168-0 1987 Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms. Gallium 10-17 transferrin Homo sapiens 63-74 3475168-0 1987 Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms. Gallium 10-17 transferrin Homo sapiens 98-109 3475407-0 1987 Inhibition of gallium-67 uptake in melanoma by an anti-human transferrin receptor monoclonal antibody. Gallium 14-21 transferrin Mus musculus 61-72 3038176-1 1987 The binding of Ga(III) to the proteolytically derived N-terminal half-molecule of human transferrin (HTF/2N) was studied by proton nuclear magnetic resonance spectroscopy. Gallium 15-17 transferrin Homo sapiens 88-99 3552800-3 1987 In this study, GA was measured in the platelet extract (PE) from eight diabetic patients who had been treated by conventional insulin therapy. Gallium 15-17 insulin Homo sapiens 126-133 3107780-7 1987 Alkaline (Alp) and acid (Acp) phosphatase activities were higher in Ga+ than in Ga- calvaria (Ga+: Alp 223 +/- 23.4 U/mg prot, Ga-: Alp 145 +/- 13.3 U/mg prot, P less than 0.02; Ga+: Acp 69.5 +/- 4.7 U/mg prot, Ga-: 57.5 +/- 2.8 U/mg prot, P less than 0.05). Gallium 68-70 PDZ and LIM domain 3 Rattus norvegicus 10-13 3660286-1 1987 In a prospective study serum C-reactive protein concentrations were measured in nine patients with "active" pulmonary sarcoidosis (as assessed by bronchoalveolar lavage lymphocyte counts, gallium-67 lung scanning, and serial pulmonary function testing), and in five patients with "inactive" disease. Gallium 188-195 C-reactive protein Homo sapiens 29-47 3465751-1 1986 Mechanisms responsible for the specific cytotoxicity of transferrin-gallium. Gallium 68-75 transferrin Homo sapiens 56-67 16665362-3 1987 The presence of C-2 double bond, as in GA(5) and deoxy-GA(5), diminished the inhibitory action of DGC. Gallium 39-41 chalcone synthase C2 Zea mays 16-19 3790721-0 1987 Inhibition of hemoglobin production by transferrin-gallium. Gallium 51-58 transferrin Homo sapiens 39-50 3790721-2 1987 Because gallium is known to bind avidly to transferrin, we examined the effect of transferrin-gallium (Tf-Ga) on hemoglobin production by Friend erythroleukemia cells in vitro. Gallium 8-15 transferrin Homo sapiens 43-54 3790721-2 1987 Because gallium is known to bind avidly to transferrin, we examined the effect of transferrin-gallium (Tf-Ga) on hemoglobin production by Friend erythroleukemia cells in vitro. Gallium 94-101 transferrin Homo sapiens 82-93 11539033-5 1987 Further, there was a significantly higher proportion of putative free GA metabolites of [3H]GA20, especially [3H]GA1, in the lower halves of normal maize relative to upper halves. Gallium 70-72 gibberellin 20-oxidase 1 Zea mays 92-96 3589113-1 1987 The pulmonary fixation of Gallium 67 has been studied by broncho-alveolar lavage (LBA) in a group of 10 cases of stage II pulmonary sarcoid, proven histologically, and in a group of 11 cases of idiopathic diffuse interstitial fibrosis (FID). Gallium 26-33 LPS responsive beige-like anchor protein Homo sapiens 82-85 3589113-2 1987 The pulmonary activity of Gallium 67 was measured in vitro in a quantitative manner on a centrifuged clump and a supernatant of LBA as well as on the serum and in vivo in a semi-quantitative manner by the Line index. Gallium 26-33 LPS responsive beige-like anchor protein Homo sapiens 128-131 3589113-4 1987 There was a narrow correlation in the serum between the Gallium 67 activity and the level of circulating transferrin. Gallium 56-63 transferrin Homo sapiens 105-116 3589113-5 1987 The fixation of Gallium in the cellular clump of LBA depends on the number of macrophages present in the clump and the total available radioactivity. Gallium 16-23 LPS responsive beige-like anchor protein Homo sapiens 49-52 3465751-6 1986 Although shunting of transferrin-gallium to another cellular compartment has not been ruled out, other studies suggest that transferrin-gallium impairs intracellular release of 59Fe from transferrin by interfering with processes responsible for intracellular acidification. Gallium 136-143 transferrin Homo sapiens 124-135 3465751-7 1986 These studies, taken together, demonstrate that inhibition of cellular iron incorporation by transferrin-gallium is a prerequisite for inhibition of cellular proliferation. Gallium 105-112 transferrin Homo sapiens 93-104 3465751-2 1986 We have previously shown that human leukemic cells proliferate normally in serum-free media containing various transferrin forms, but the addition of transferrin-gallium leads to inhibition of cellular proliferation. Gallium 162-169 transferrin Homo sapiens 150-161 3465751-4 1986 The cytotoxicity of gallium is considerably enhanced by its binding to transferrin and cytotoxicity can be reversed by transferrin-iron but not by other transferrin forms. Gallium 20-27 transferrin Homo sapiens 71-82 3465751-4 1986 The cytotoxicity of gallium is considerably enhanced by its binding to transferrin and cytotoxicity can be reversed by transferrin-iron but not by other transferrin forms. Gallium 20-27 transferrin Homo sapiens 119-130 3465751-4 1986 The cytotoxicity of gallium is considerably enhanced by its binding to transferrin and cytotoxicity can be reversed by transferrin-iron but not by other transferrin forms. Gallium 20-27 transferrin Homo sapiens 119-130 3465751-5 1986 Exposure to transferrin-gallium leads to a marked increase in cell surface transferrin binding sites, but despite this, cellular 59Fe incorporation is inappropriately low. Gallium 24-31 transferrin Homo sapiens 12-23 3465751-5 1986 Exposure to transferrin-gallium leads to a marked increase in cell surface transferrin binding sites, but despite this, cellular 59Fe incorporation is inappropriately low. Gallium 24-31 transferrin Homo sapiens 75-86 3465751-6 1986 Although shunting of transferrin-gallium to another cellular compartment has not been ruled out, other studies suggest that transferrin-gallium impairs intracellular release of 59Fe from transferrin by interfering with processes responsible for intracellular acidification. Gallium 33-40 transferrin Homo sapiens 21-32 3465751-6 1986 Although shunting of transferrin-gallium to another cellular compartment has not been ruled out, other studies suggest that transferrin-gallium impairs intracellular release of 59Fe from transferrin by interfering with processes responsible for intracellular acidification. Gallium 136-143 transferrin Homo sapiens 124-135 3484946-3 1986 The quantitative interaction of complement components C3a and C5a with GA, however, is not clearly defined. Gallium 71-73 complement C3 Homo sapiens 54-57 3964644-3 1986 Comparison of these results with literature values for the gallium-transferrin binding constants indicates that lactoferrin binds gallium more strongly by a factor of approximately 90. Gallium 59-66 transferrin Homo sapiens 67-78 3012026-0 1986 Enhancement of hepatic gallium-67 uptake by asialo-transferrin. Gallium 23-30 transferrin Homo sapiens 51-62 3484946-3 1986 The quantitative interaction of complement components C3a and C5a with GA, however, is not clearly defined. Gallium 71-73 complement C5a receptor 1 Homo sapiens 62-65 3484946-4 1986 This study evaluates the relationship of GA responses to plasma levels of C5a and C3a in zymosan-activated plasma (ZAP). Gallium 41-43 complement C5a receptor 1 Homo sapiens 74-77 3484946-4 1986 This study evaluates the relationship of GA responses to plasma levels of C5a and C3a in zymosan-activated plasma (ZAP). Gallium 41-43 complement C3 Homo sapiens 82-85 10032115-0 1985 Bistability and metastability of the gallium vacancy in GaAs: The actuator of EL2? Gallium 37-44 spectrin alpha, erythrocytic 1 Homo sapiens 78-81 3014956-10 1986 Thus, systemic inflammation may facilitate pulmonary gallium-67 uptake, possibly by changes in BAL fluid or serum transferrin saturation and/or kinetics. Gallium 53-60 transferrin Homo sapiens 114-125 3014957-9 1986 Subjects with increased levels of SACE or serum alpha 1-AT showed higher lavage gallium-67 activity than did normals, but no correlation could be established. Gallium 80-87 serpin family A member 1 Homo sapiens 48-58 3859411-5 1985 Ga accumulation was decreased by adding human transferrin (0.5 mg/ml). Gallium 0-2 transferrin Homo sapiens 46-57 3859476-3 1985 The tumor and tissue uptakes of 67Ga were calculated when the radioactivity was administered either as 67Ga-citrate or 67Ga-transferrin (Ga-Tf). Gallium 34-36 transferrin Mus musculus 124-135 2994247-3 1985 There was a positive correlation between serum angiotensin converting enzyme activity and an index of pulmonary gallium uptake assessed by the National Institutes of Health method (r = 0.7, p less than 0.001). Gallium 112-119 angiotensin I converting enzyme Homo sapiens 47-76 3866752-3 1985 Exploitation of reaction-rate differences in metal ion transference from Ga-cit to Tf (slow) and Fe-nitrilotriacetate (Fe-NTA) to Tf (fast) is put to use to attain a proper tumor/tissue ratio within practical time limits. Gallium 73-75 transferrin Homo sapiens 83-85 3866752-3 1985 Exploitation of reaction-rate differences in metal ion transference from Ga-cit to Tf (slow) and Fe-nitrilotriacetate (Fe-NTA) to Tf (fast) is put to use to attain a proper tumor/tissue ratio within practical time limits. Gallium 73-75 transferrin Homo sapiens 130-132 3911164-3 1985 Oxytocin produced a large and sustained increase in the amiloride-inhibitable short circuit current (Im) which was accompanied by a large increase of both apical and basolateral membrane conductance (ga and gb, respectively). Gallium 200-202 oxytocin/neurophysin I prepropeptide Homo sapiens 0-8 3911164-5 1985 Insulin also increased Im, ga and gb. Gallium 27-29 insulin Homo sapiens 0-7 6592293-2 1984 The results indicate that: (a) the liver can take up Ga-67 and secrete it into the bile, even in the absence of transferrin; (b) transferrin inhibits hepatic uptake of Ga-67 and its biliary excretion; and (c) iron deficiency markedly enhances hepatic uptake of Ga-67. Gallium 53-55 transferrin Rattus norvegicus 129-140 6208685-11 1984 (v) Precipitates of gA from infected cells labeled for a short pulse contained gA2 and gA3 which appear to be products of rapid glycosylation. Gallium 20-22 electron transfer flavoprotein subunit alpha Homo sapiens 79-82 6208685-11 1984 (v) Precipitates of gA from infected cells labeled for a short pulse contained gA2 and gA3 which appear to be products of rapid glycosylation. Gallium 20-22 succinyl-CoA:glutarate-CoA transferase Homo sapiens 87-90 6592293-2 1984 The results indicate that: (a) the liver can take up Ga-67 and secrete it into the bile, even in the absence of transferrin; (b) transferrin inhibits hepatic uptake of Ga-67 and its biliary excretion; and (c) iron deficiency markedly enhances hepatic uptake of Ga-67. Gallium 168-170 transferrin Rattus norvegicus 129-140 6592293-2 1984 The results indicate that: (a) the liver can take up Ga-67 and secrete it into the bile, even in the absence of transferrin; (b) transferrin inhibits hepatic uptake of Ga-67 and its biliary excretion; and (c) iron deficiency markedly enhances hepatic uptake of Ga-67. Gallium 168-170 transferrin Rattus norvegicus 129-140 6235327-5 1984 Gallium-67 was excellent in ruling out OM when the study was normal, or in ruling in OM when the relative uptake of Ga-67 exceeded the uptake of Tc-99m MDP, or when the Ga-67 in bone had a different distribution from the TPBS. Gallium 0-7 chondroitin sulfate synthase 1 Homo sapiens 221-225 6331627-0 1984 Positive gallium scan in the syndrome of opsoclonus-myoclonus treated with adrenocorticotropic hormone. Gallium 9-16 proopiomelanocortin Homo sapiens 75-102 6235327-5 1984 Gallium-67 was excellent in ruling out OM when the study was normal, or in ruling in OM when the relative uptake of Ga-67 exceeded the uptake of Tc-99m MDP, or when the Ga-67 in bone had a different distribution from the TPBS. Gallium 0-2 chondroitin sulfate synthase 1 Homo sapiens 221-225 6313303-3 1983 Serum ACE levels and changes in ACE level correlated best with the clinical status of patients and their gallium scans (p less than 0.0005), and less with their chest x-ray films (p = 0.012) or PFTs (p = 0.007). Gallium 105-112 angiotensin I converting enzyme Homo sapiens 6-9 6729942-3 1984 Only two GA positive sera had reactivity for previously defined granulocyte specific antigens (one NA1 and NB1 ). Gallium 9-11 CD177 molecule Homo sapiens 107-110 6313303-3 1983 Serum ACE levels and changes in ACE level correlated best with the clinical status of patients and their gallium scans (p less than 0.0005), and less with their chest x-ray films (p = 0.012) or PFTs (p = 0.007). Gallium 105-112 angiotensin I converting enzyme Homo sapiens 32-35 6313760-8 1983 After exposure to transferrin-gallium, proliferation ceased, but cells exhibited increased surface receptor and were arrested at S phase of the cell cycle without associated myeloid differentiation. Gallium 30-37 transferrin Homo sapiens 18-29 6678619-2 1983 Addition of transferrin has no effect on the uptake into non-viable cells but in viable cells it increases the uptake of Fe and Ga but decreases that of Pu. Gallium 128-130 transferrin Homo sapiens 12-23 6313760-11 1983 Finally, the way in which gallium salts are currently being investigated as chemotherapeutic agents should be reevaluated in light of our findings concerning transferrin-gallium effects on cellular proliferation. Gallium 170-177 transferrin Homo sapiens 158-169 6864313-0 1983 In vitro transfer of Ga-67 from transferrin to ferritin. Gallium 21-23 transferrin Homo sapiens 32-43 6402006-7 1983 The strength of transferrin complexation is also compared to that of a series of low molecular weight ligands by using calculated pM values (pM = -log [Ga-(H2O)6]) to express the effective binding strength at pH 7.4. Gallium 152-154 transferrin Homo sapiens 16-27 7236888-4 1981 GA antibodies caused reduced granulocyte recovery and t 1/2 in three of three non-neutropenic patients (one with anti-NB1), increased sequestration of cells in the liver, and failure of granulocytes to localize at sites of infection in two of two patients (one with anti-NA1). Gallium 0-2 CD177 molecule Homo sapiens 118-121 6402006-4 1983 Therefore, thermodynamic binding constants for gallium complexation at the two specific metal binding sites of human serum transferrin at pH 7.4 and 5 mM NaHCO3 have been determined by UV difference spectroscopy. Gallium 47-54 transferrin Homo sapiens 123-134 6889967-5 1982 This enhanced toxicity was consistent with, and proportional to, the increased gallium uptake in the presence of transferrin rather than a direct effect of this iron transport protein. Gallium 79-86 transferrin Mus musculus 113-124 6897227-4 1982 When plasma from rabbits injection 67Ga-citrate was dialyzed at pH 6.5-7.5, dissociation of Ga from transferrin showed an inverse pH-dependence. Gallium 37-39 serotransferrin Oryctolagus cuniculus 100-111 6897227-5 1982 A similar inverse dependence on pH was observed for the uptake of Ga by L1210 leukemia cells and Ehrlich ascites cells incubated with Ga-transferrin complex. Gallium 66-68 serotransferrin Oryctolagus cuniculus 137-148 6261931-4 1981 Gallium-67 scans proved to be accurate in detecting thoracic and extrathoracic metastases in the 30 patients with SCC, especially within the liver and lymph node-bearing area. Gallium 0-7 serpin family B member 3 Homo sapiens 114-117 7327855-0 1981 The effects of differing gallium-transferrin-anion complexes on the tumor uptake of gallium-67. Gallium 84-91 transferrin Homo sapiens 33-44 6255609-1 1980 We have described two patients who had positive gallium lung scans with simultaneous elevation in serum angiotensin converting enzyme (SACE) levels. Gallium 48-55 angiotensin I converting enzyme Homo sapiens 104-133 541730-0 1979 A transferrin-mediated uptake of gallium-67 by EMT-6 sarcoma. Gallium 33-40 transferrin Homo sapiens 2-13 7205378-6 1981 We conclude that the initial in vivo entry of Ga-67 into tumor tissue involves mainly an unbound or loosely bound form of Ga-67, whereas its uptake by normal soft tissues is strongly promoted by its binding to transferrin. Gallium 46-48 transferrin Homo sapiens 210-221 6766237-0 1980 Gallium scanning in Paget"s disease of bone: effect of calcitonin. Gallium 0-7 calcitonin related polypeptide alpha Homo sapiens 55-65 6766237-4 1980 In each case the beneficial effect of calcitonin was demonstrated more accurately with gallium than with technetium diphosphonate. Gallium 87-94 calcitonin related polypeptide alpha Homo sapiens 38-48 7356736-9 1980 Gallium-67, pre-bound to transferrin vitro, did not accumulate at the site of histamine or transferrin injection, but there was a slight accumulation at the lactoferrin site. Gallium 0-7 serotransferrin Oryctolagus cuniculus 25-36 541730-4 1979 In this system, the addition of transferrin to the medium was required before an appreciable cellular uptake of Ga-67 occurred. Gallium 112-114 transferrin Homo sapiens 32-43 541730-6 1979 EMT-6 tumor-cell uptake of Ga-67 was probably mediated by a specific cellular receptor for transferrin. Gallium 27-29 transferrin Mus musculus 91-102 541730-8 1979 Over the experimental range of transferrin concentration in the medium, the observed uptake of Ga-67 was closely correlated with the degree of formation of Ga-67-labeled transferrin and the fraction of transferrin bound to the cellular receptor (N = 69, r = 0.86, p less than 0.0001). Gallium 95-97 transferrin Homo sapiens 31-42 541730-8 1979 Over the experimental range of transferrin concentration in the medium, the observed uptake of Ga-67 was closely correlated with the degree of formation of Ga-67-labeled transferrin and the fraction of transferrin bound to the cellular receptor (N = 69, r = 0.86, p less than 0.0001). Gallium 95-97 transferrin Homo sapiens 170-181 541730-8 1979 Over the experimental range of transferrin concentration in the medium, the observed uptake of Ga-67 was closely correlated with the degree of formation of Ga-67-labeled transferrin and the fraction of transferrin bound to the cellular receptor (N = 69, r = 0.86, p less than 0.0001). Gallium 95-97 transferrin Homo sapiens 170-181 541731-0 1979 A transferrin-mediated uptake of gallium-67 by EMT-6 sarcoma. Gallium 33-40 transferrin Mus musculus 2-13 120419-1 1979 Because of the high stability constant of gallium transferrin, the formation of a protein that will be stable in vivo and labeled with gallium-68 (a positron emitter) requires preliminary coupling of a strong chelating group to the protein. Gallium 135-143 transferrin Homo sapiens 50-61 6243376-0 1980 Common pathway for tumor cell uptake of gallium-67 and iron-59 via a transferrin receptor. Gallium 40-47 transferrin receptor Mus musculus 69-89 218481-3 1979 Three of four patients with normal or borderline-elevated levels of angiotensin-converting enzyme also had positive gallium-scan results. Gallium 116-123 angiotensin I converting enzyme Homo sapiens 68-97 226345-6 1979 The toxin (1 microgram/ml)- (but not TSH-) induced increase in ODC was abolished by inclusion of ganglioside Ga and GT1 were without effect. Gallium 109-111 ornithine decarboxylase 1 Rattus norvegicus 63-66 120419-1 1979 Because of the high stability constant of gallium transferrin, the formation of a protein that will be stable in vivo and labeled with gallium-68 (a positron emitter) requires preliminary coupling of a strong chelating group to the protein. Gallium 42-49 transferrin Homo sapiens 50-61 528144-0 1979 On the role of transferrin in the uptake of gallium by tumor cells. Gallium 44-51 transferrin Homo sapiens 15-26 369847-4 1978 The ratio of [14C]A-LH to [3H]GA-LH (14C:3H ratio) in the tissue decreased significantly with time and with GnRH treatment. Gallium 30-32 gonadotropin releasing hormone 1 Rattus norvegicus 108-112 670609-6 1978 The binding of 125I GA by serum IgE antibody from 7 grass-sensitive patients ranged from 0.6 ng GA P bound per ml to 15 ng. Gallium 20-22 immunoglobulin heavy constant epsilon Homo sapiens 32-35 682025-2 1978 The study arose out of previously reported tissue-culture work showing marked transferrin stimulation of Ga-67 and Fe-59 uptakes by cultured cells from mouse lymphoid tumors. Gallium 105-107 transferrin Mus musculus 78-89 621568-0 1978 Imaging the bowel with technetium--an aid in gallium studies. Gallium 45-52 activation induced cytidine deaminase Homo sapiens 38-41 40794-0 1979 Simple, fast preparation of gallium-68-labelled human serum albumin microspheres. Gallium 28-35 albumin Homo sapiens 54-67 921926-1 1977 The addition of trivalent iron, gallium, and terbium ions to the metal binding sites of human transferrin has been investigated by fluorescence and spectrophotometric measurements. Gallium 32-39 transferrin Homo sapiens 94-105 1168730-0 1975 Gallium-67 citrate uptake by cultured tumor cells, stimulated by serum transferrin. Gallium 0-7 transferrin Mus musculus 71-82 1002991-4 1976 Preimmunization with GA suppresses GA-MBSA as well as GAT-MBSA and GT-MBSA plaque-forming cell (PFC) responses in DBA/1 mice. Gallium 21-23 glycine-N-acyltransferase Mus musculus 54-57 809553-1 1975 Gallium-68 (T 1/2 68 min) is a convenient label for radiopharmaceuticals designed for use with positron detection devices; the radionuclide is a generator produce obtained from its parent 68Ge (T 1/2 287 days). Gallium 0-7 interleukin 1 receptor like 1 Homo sapiens 12-24 809553-1 1975 Gallium-68 (T 1/2 68 min) is a convenient label for radiopharmaceuticals designed for use with positron detection devices; the radionuclide is a generator produce obtained from its parent 68Ge (T 1/2 287 days). Gallium 0-7 interleukin 1 receptor like 1 Homo sapiens 12-15 33386852-5 2021 An ortholog of Arabidopsis thaliana GA3-oxidase 1 (GA3ox1), MtGA3ox1/SSL, is required for GA biosynthesis. Gallium 36-38 gibberellin 3-oxidase 1 Arabidopsis thaliana 51-57 4817579-0 1974 On the binding of gallium to transferrin. Gallium 18-25 transferrin Homo sapiens 29-40 18960143-1 1967 A systematic study has been made of the solvent extraction behaviour of milligram amounts of gallium(III), indium(III), and thallium(III) with TBP from hydrochloric acid, and of thallium(III) from nitric acid, sulphuric acid and buffer solutions of different pH. Gallium 93-100 TATA-box binding protein Homo sapiens 143-146 33744539-2 2021 Here, ultrafine bimetallic Ga-Pt nanocatalysts encapsulated into silicalite-1 (S-1) zeolites (GaPt@S-1) were synthesized by a facile ligand-protected direct H2-reduction method. Gallium 27-29 GRB2 binding adaptor protein, transmembrane Homo sapiens 94-98 33756153-5 2021 Previously, peptide analogs of the p65 binding domain of GILZ, referred to as GA have been shown to suppress pathology in the lipopolysaccharide induced model of neuroinflammation. Gallium 78-80 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 35-38 33756153-5 2021 Previously, peptide analogs of the p65 binding domain of GILZ, referred to as GA have been shown to suppress pathology in the lipopolysaccharide induced model of neuroinflammation. Gallium 78-80 TSC22 domain family, member 3 Mus musculus 57-61 33756153-8 2021 GA was observed in proximity with NeuN positive neurons suggesting that the compound crossed the blood brain barrier to reach the brain parenchyma. Gallium 0-2 RNA binding protein, fox-1 homolog (C. elegans) 3 Mus musculus 34-38 33756153-9 2021 Further, GA treatment decreased Abeta load, reduced Iba1 + microglia and glial fibrillary acidic protein (GFAP)+ astrocytes, inhibited inflammatory cytokines and suppressed toll like receptor (TLR-2, TLR-4) expressions in 5xFAD mice. Gallium 9-11 amyloid beta (A4) precursor protein Mus musculus 32-37 33756153-9 2021 Further, GA treatment decreased Abeta load, reduced Iba1 + microglia and glial fibrillary acidic protein (GFAP)+ astrocytes, inhibited inflammatory cytokines and suppressed toll like receptor (TLR-2, TLR-4) expressions in 5xFAD mice. Gallium 9-11 induction of brown adipocytes 1 Mus musculus 52-56 33756153-9 2021 Further, GA treatment decreased Abeta load, reduced Iba1 + microglia and glial fibrillary acidic protein (GFAP)+ astrocytes, inhibited inflammatory cytokines and suppressed toll like receptor (TLR-2, TLR-4) expressions in 5xFAD mice. Gallium 9-11 glial fibrillary acidic protein Mus musculus 73-104 33756153-9 2021 Further, GA treatment decreased Abeta load, reduced Iba1 + microglia and glial fibrillary acidic protein (GFAP)+ astrocytes, inhibited inflammatory cytokines and suppressed toll like receptor (TLR-2, TLR-4) expressions in 5xFAD mice. Gallium 9-11 glial fibrillary acidic protein Mus musculus 106-110 33756153-9 2021 Further, GA treatment decreased Abeta load, reduced Iba1 + microglia and glial fibrillary acidic protein (GFAP)+ astrocytes, inhibited inflammatory cytokines and suppressed toll like receptor (TLR-2, TLR-4) expressions in 5xFAD mice. Gallium 9-11 toll-like receptor 2 Mus musculus 193-198 33756153-9 2021 Further, GA treatment decreased Abeta load, reduced Iba1 + microglia and glial fibrillary acidic protein (GFAP)+ astrocytes, inhibited inflammatory cytokines and suppressed toll like receptor (TLR-2, TLR-4) expressions in 5xFAD mice. Gallium 9-11 toll-like receptor 4 Mus musculus 200-205 982614-1 1976 The activity of cholinesterase in different areas of the rat brain was studied as affected by two organophosphophorous inhibitors of the enzyme from the group of O-alkyl-S-hexylthiophosphonates, GA-89 and GA-95. Gallium 195-197 butyrylcholinesterase Rattus norvegicus 16-30 982614-1 1976 The activity of cholinesterase in different areas of the rat brain was studied as affected by two organophosphophorous inhibitors of the enzyme from the group of O-alkyl-S-hexylthiophosphonates, GA-89 and GA-95. Gallium 205-207 butyrylcholinesterase Rattus norvegicus 16-30 982614-3 1976 Under the effect of GA-89 inhibition of cholinesterase in the brain is considerably higher than in blood, under the effect of GA-95 an inverse relation is observed. Gallium 20-22 butyrylcholinesterase Rattus norvegicus 40-54 16658386-6 1973 In the presence of GA(3), beta-amylase decreases at a slower rate. Gallium 19-21 beta-amylase Triticum aestivum 26-38 33459068-5 2021 EXPERT OPINION: : PSMA-targeted imaging agents labeled with radionuclides such as fluorine-18, copper-64, gallium-68, and technetium-99m have been successfully translated into clinical phase for the early diagnosis of metastatic prostate cancer. Gallium 106-113 folate hydrolase 1 Homo sapiens 18-22 34036786-3 2021 Here, we report the controlled growth of vertical GaSe/MoS2 p-n heterojunctions via a liquid gallium (Ga)-assisted chemical vapor deposition method. Gallium 93-100 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 60-63 34036786-3 2021 Here, we report the controlled growth of vertical GaSe/MoS2 p-n heterojunctions via a liquid gallium (Ga)-assisted chemical vapor deposition method. Gallium 50-52 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 60-63 34021667-0 2021 PET/CT using 68 Ga-PSMA-617 versus 18 F-fluorodeoxyglucose to differentiate low- and high-grade gliomas. Gallium 16-18 folate hydrolase 1 Homo sapiens 19-23 34021667-9 2021 The Youden index for SUVmax and SUVmean of 68 Ga-PSMA-617 and 18 F-FDG were 0.82 and 0.79 and 0.54 and 0.61, separately. Gallium 46-48 folate hydrolase 1 Homo sapiens 49-53 34019920-6 2021 Too high SA concentration (CS:GA = 1:2) might also promote the accumulation of moisture. Gallium 30-32 acyl-CoA synthetase medium chain family member 3 Homo sapiens 9-11 34019920-8 2021 In all, the addition of the proper level SA (CS:GA = 1:1-1:2) could increase the stability of CS particle-stabilized Pickering emulsion. Gallium 48-50 acyl-CoA synthetase medium chain family member 3 Homo sapiens 41-43 34019920-8 2021 In all, the addition of the proper level SA (CS:GA = 1:1-1:2) could increase the stability of CS particle-stabilized Pickering emulsion. Gallium 48-50 citrate synthase Homo sapiens 45-47 34019920-8 2021 In all, the addition of the proper level SA (CS:GA = 1:1-1:2) could increase the stability of CS particle-stabilized Pickering emulsion. Gallium 48-50 citrate synthase Homo sapiens 94-96 33963401-5 2021 Expression of HBI1 and BEE2 was induced in response to BR and GA treatment. Gallium 62-64 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 14-18 33963401-5 2021 Expression of HBI1 and BEE2 was induced in response to BR and GA treatment. Gallium 62-64 BR enhanced expression 2 Arabidopsis thaliana 23-27 33963401-6 2021 In addition, HBI1 or BEE2 overexpressing Arabidopsis plants are less sensitive to the BR biosynthesis inhibitor, brassinazole, and the GA biosynthesis inhibitor, paclobutrazol. Gallium 135-137 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 13-17 33963401-6 2021 In addition, HBI1 or BEE2 overexpressing Arabidopsis plants are less sensitive to the BR biosynthesis inhibitor, brassinazole, and the GA biosynthesis inhibitor, paclobutrazol. Gallium 135-137 BR enhanced expression 2 Arabidopsis thaliana 21-25 33991504-4 2021 UBQLN2 could recognize HSP70 ubiquitination, which facilitates the UBQLN2-HSP70-GA complex formation and promotes poly-GA degradation. Gallium 80-82 ubiquilin 2 Homo sapiens 0-6 33991504-4 2021 UBQLN2 could recognize HSP70 ubiquitination, which facilitates the UBQLN2-HSP70-GA complex formation and promotes poly-GA degradation. Gallium 80-82 heat shock protein family A (Hsp70) member 4 Homo sapiens 23-28 34046684-4 2021 Here, we show that CRY1 signaling involves the inhibition of GA signaling through repression of GA-induced degradation of DELLA proteins. Gallium 61-63 cryptochrome 1 Arabidopsis thaliana 19-23 33991504-4 2021 UBQLN2 could recognize HSP70 ubiquitination, which facilitates the UBQLN2-HSP70-GA complex formation and promotes poly-GA degradation. Gallium 80-82 ubiquilin 2 Homo sapiens 67-73 33991504-4 2021 UBQLN2 could recognize HSP70 ubiquitination, which facilitates the UBQLN2-HSP70-GA complex formation and promotes poly-GA degradation. Gallium 80-82 heat shock protein family A (Hsp70) member 4 Homo sapiens 74-79 33931929-1 2021 OBJECTIVE: To evaluate the diagnostic accuracy of the 68 Gallium (68 Ga) - prostate specific membrane antigen (PSMA) positron emission tomography/magnetic resonance imaging (PET/MRI) and multiparametric MRI (mpMRI) by region-based comparison of index tumour localisations using histopathological tumour maps of patients who underwent radical prostatectomy due to clinically significant prostate cancer. Gallium 57-64 folate hydrolase 1 Homo sapiens 111-115 33451923-11 2021 CONCLUSION: These results could stimulate clinicians to perform Ga-68 PET for treatment decisions, especially in patients with high CEA and Ctn levels at the time of diagnosis. Gallium 64-66 CEA cell adhesion molecule 3 Homo sapiens 132-135 33451923-11 2021 CONCLUSION: These results could stimulate clinicians to perform Ga-68 PET for treatment decisions, especially in patients with high CEA and Ctn levels at the time of diagnosis. Gallium 64-66 calcitonin related polypeptide alpha Homo sapiens 140-143 33946599-1 2021 It has been herein presented that a microemulsion, known to be an effective and safe drug delivery system following intravenous administration, can be loaded with traces of [68Ga]Ga-PSMA-617 without losing its properties or causing toxicity. Gallium 176-178 folate hydrolase 1 Homo sapiens 182-186 33904185-5 2021 Both the transcript and protein levels of HAT1 are induced by GA, while increased HAT1, in return, suppresses GA biosynthesis and signaling, thus forming a negative feedback regulatory loop that controls GA homeostasis to fine-tune trichome development and cotyledon expansion. Gallium 62-64 histone acetyltransferase 1 Homo sapiens 42-46 33760124-8 2021 A pronounced increase in the OCR, and decreases in the cell proliferation, glucose uptake capacity, lactic acid content, ECAR and HK2 expression were detected in LC cells subjected to GA treatment or HK2-knockdown. Gallium 184-186 hexokinase 2 Homo sapiens 130-133 33760124-11 2021 In conclusion, GA may inhibit the Warburg effect and cell proliferation in LC by suppressing HK2 through blockade of the PI3K/AKT signaling pathway. Gallium 15-17 hexokinase 2 Homo sapiens 93-96 33760124-11 2021 In conclusion, GA may inhibit the Warburg effect and cell proliferation in LC by suppressing HK2 through blockade of the PI3K/AKT signaling pathway. Gallium 15-17 AKT serine/threonine kinase 1 Homo sapiens 126-129 33848118-4 2021 Using these three compounds, we verified that coinjection of CBT-NODA-68Ga with CBT-NODA or CBT-NODA-Ga could lead to the synthesis of hybrid gallium-68 nanoparticles in furin-overexpressing cancer cells and enhance microPET tumor imaging in mice. Gallium 142-149 furin (paired basic amino acid cleaving enzyme) Mus musculus 170-175 33904185-5 2021 Both the transcript and protein levels of HAT1 are induced by GA, while increased HAT1, in return, suppresses GA biosynthesis and signaling, thus forming a negative feedback regulatory loop that controls GA homeostasis to fine-tune trichome development and cotyledon expansion. Gallium 110-112 histone acetyltransferase 1 Homo sapiens 82-86 33904185-5 2021 Both the transcript and protein levels of HAT1 are induced by GA, while increased HAT1, in return, suppresses GA biosynthesis and signaling, thus forming a negative feedback regulatory loop that controls GA homeostasis to fine-tune trichome development and cotyledon expansion. Gallium 110-112 histone acetyltransferase 1 Homo sapiens 82-86 33904185-9 2021 Our findings demonstrate that HAT1 functions as a critical repressor to regulate the GA-mediated trichome initiation and cotyledon growth; meanwhile they uncover a novel mechanism by which the plant regulates trichome initiation and cotyledon expansion through HAT1-DELLA regulatory module under various GA concentrations. Gallium 85-87 histone acetyltransferase 1 Homo sapiens 30-34 33904185-9 2021 Our findings demonstrate that HAT1 functions as a critical repressor to regulate the GA-mediated trichome initiation and cotyledon growth; meanwhile they uncover a novel mechanism by which the plant regulates trichome initiation and cotyledon expansion through HAT1-DELLA regulatory module under various GA concentrations. Gallium 85-87 histone acetyltransferase 1 Homo sapiens 261-265 33904185-9 2021 Our findings demonstrate that HAT1 functions as a critical repressor to regulate the GA-mediated trichome initiation and cotyledon growth; meanwhile they uncover a novel mechanism by which the plant regulates trichome initiation and cotyledon expansion through HAT1-DELLA regulatory module under various GA concentrations. Gallium 304-306 histone acetyltransferase 1 Homo sapiens 30-34 33904185-9 2021 Our findings demonstrate that HAT1 functions as a critical repressor to regulate the GA-mediated trichome initiation and cotyledon growth; meanwhile they uncover a novel mechanism by which the plant regulates trichome initiation and cotyledon expansion through HAT1-DELLA regulatory module under various GA concentrations. Gallium 304-306 histone acetyltransferase 1 Homo sapiens 261-265 33948339-6 2021 The majority (92.1%) of examinations were 68-Gallium-labeled prostate-specific membrane antigen (68Ga-PSMA) positron emission tomography/computed tomography (PET/CT). Gallium 45-52 folate hydrolase 1 Homo sapiens 61-106 33735342-1 2021 The reactions of SbH3 with one or two equivalents of (Dipp2NacNac)Ga (Dipp2NacNac = HC{C(Me)N(Dipp)}2; Dipp = 2,6-iPr2C6H3) yield the primary and secondary stibanes (Dipp2NacNac)GaH(SbH2) (3) and {(Dipp2NacNac)GaH}2(SbH) (5). Gallium 66-68 nudix hydrolase 3 Homo sapiens 54-58 33876023-1 2021 Gallium (as Ga3+) is a Group IIIa metal and its recovery from wastewaters has become increasingly important for its reuse. Gallium 0-7 succinyl-CoA:glutarate-CoA transferase Homo sapiens 12-15 33789933-2 2021 The gallium-68 labeled GRPr antagonist SB3 (68Ga SB3) has shown excellent results in (pre)clinical studies and was selected for further clinical investigation. Gallium 4-11 gastrin releasing peptide receptor Homo sapiens 23-27 33996472-1 2021 Objective: To evaluate the use of Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (68Ga-PSMA PET/CT), compared with conventional CT abdomen/pelvis (CTAP) and whole body single photon emission CT bone scan (BS), for detection of local or distant metastasis following biochemical failure/recurrence in post-prostatectomy patients. Gallium 34-41 folate hydrolase 1 Homo sapiens 135-139 32817143-2 2021 A gallium 68-labeled peptide of Siglec-9, 68Ga-DOTA-Siglec-9, holds promise as a novel PET tracer for imaging of inflammation. Gallium 2-9 sialic acid binding Ig like lectin 9 Homo sapiens 32-40 32817143-2 2021 A gallium 68-labeled peptide of Siglec-9, 68Ga-DOTA-Siglec-9, holds promise as a novel PET tracer for imaging of inflammation. Gallium 2-9 sialic acid binding Ig like lectin 9 Homo sapiens 52-60 33788556-0 2021 Imaging Somatostatin Positive Tumors with Tyr3-Octreotate/Octreotide Conjugated to Desferrioxamine B Squaramide Radiolabeled with either Zirconium-89 or Gallium-68. Gallium 153-160 somatostatin Homo sapiens 8-20 33746213-10 2021 Molecular response on Gallium-68 PSMA positron emission tomography/computed tomography was noted in 74% (95% CI: 50.1-92.1%) of the patients. Gallium 22-29 folate hydrolase 1 Homo sapiens 33-37 33743092-5 2021 Introduction of a small amount of Ga into the reactor leads to the formation of GaP nanowires instead of ternary InGaP nanowires. Gallium 34-36 regenerating family member 3 alpha Homo sapiens 113-118 33744997-4 2021 In this publication, AgOX wetting layers were applied to OMO electrodes to improve the performance of Cu(In,Ga)Se2 (CIGS) thin-film solar cells. Gallium 108-110 fucosyltransferase 2 Homo sapiens 111-114 33730027-6 2021 The transcription factor basic region/leucine zipper motif 53 (bZIP53), which is strongly correlated with cellulose synthase gene 1 (CesA1) expression, was screened by transcriptome sequencing and the expression of the cellulose synthase gene in maize grain development after GA treatment was determined. Gallium 276-278 cellulose synthase-1 Zea mays 106-131 33730027-6 2021 The transcription factor basic region/leucine zipper motif 53 (bZIP53), which is strongly correlated with cellulose synthase gene 1 (CesA1) expression, was screened by transcriptome sequencing and the expression of the cellulose synthase gene in maize grain development after GA treatment was determined. Gallium 276-278 cellulose synthase-1 Zea mays 133-138 33300428-6 2021 Here we show that a mutation which reduces sensitivity to BR (bri1-6) prevents ShHTL7 from promoting GA-independent germination. Gallium 101-103 Leucine-rich receptor-like protein kinase family protein Arabidopsis thaliana 62-68 33245515-6 2021 ELISA analysis found that GA dose-dependently reduced the production of pro-inflammatory mediators TNF-alpha and IL-1beta. Gallium 26-28 tumor necrosis factor Homo sapiens 99-108 33245515-6 2021 ELISA analysis found that GA dose-dependently reduced the production of pro-inflammatory mediators TNF-alpha and IL-1beta. Gallium 26-28 interleukin 1 alpha Homo sapiens 113-121 33245515-9 2021 RT-qPCR showed that GA significantly increased the mRNA levels of Heme oxygenase-1 (HO-1) and NADPH:quinone oxidoreductase1 (NQO1). Gallium 20-22 heme oxygenase 1 Homo sapiens 66-82 33245515-9 2021 RT-qPCR showed that GA significantly increased the mRNA levels of Heme oxygenase-1 (HO-1) and NADPH:quinone oxidoreductase1 (NQO1). Gallium 20-22 heme oxygenase 1 Homo sapiens 84-88 33245515-9 2021 RT-qPCR showed that GA significantly increased the mRNA levels of Heme oxygenase-1 (HO-1) and NADPH:quinone oxidoreductase1 (NQO1). Gallium 20-22 NAD(P)H quinone dehydrogenase 1 Homo sapiens 94-123 33245515-9 2021 RT-qPCR showed that GA significantly increased the mRNA levels of Heme oxygenase-1 (HO-1) and NADPH:quinone oxidoreductase1 (NQO1). Gallium 20-22 NAD(P)H quinone dehydrogenase 1 Homo sapiens 125-129 33245515-10 2021 Furthermore, Nrf2 siRNA transfection confirmed the above effects of GA. Gallium 68-70 NFE2 like bZIP transcription factor 2 Homo sapiens 13-17 33245515-11 2021 In total, subtoxic doses of GA significantly flattened the inflammatory response induced by HG and PA in ARPE-19 cells via modulating the Nrf2 signaling pathway. Gallium 28-30 NFE2 like bZIP transcription factor 2 Homo sapiens 138-142 33186177-3 2021 Subjects with gallium PSMA PET-CT and multiparametric prostate MRI performed according to Prostate Imaging Reporting and Data System v2 criteria in our clinic were included in the study. Gallium 14-21 folate hydrolase 1 Homo sapiens 22-26 33230789-1 2021 Cu(In,Ga)Se2 (CIGS) absorbers are prepared by direct current electrodeposition process followed by selenization of precursors. Gallium 6-8 fucosyltransferase 2 Homo sapiens 9-12 33672373-0 2021 The Use of a Non-Conventional Long-Lived Gallium Radioisotope 66Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR:2377 Affibody Molecule. Gallium 41-48 epidermal growth factor receptor Homo sapiens 96-100 32826958-14 2021 When mpMRI and Ga-68 PSMA PET were used in combination detection rates of ECE and SVI increased to 65.1 and 61.5%. Gallium 15-17 folate hydrolase 1 Homo sapiens 21-25 33464824-5 2021 GA revealed excellent efficiency for removal of highly toxic metals, such as Cd2+ and Pb2+. Gallium 0-2 CD2 molecule Homo sapiens 77-80 33534535-1 2021 Silver alloying of Cu(In,Ga)Se2 absorbers for thin film photovoltaics offers improvements in open-circuit voltage, especially when combined with optimal alkali-treatments and certain Ga concentrations. Gallium 25-27 fucosyltransferase 2 Homo sapiens 28-31 33534535-1 2021 Silver alloying of Cu(In,Ga)Se2 absorbers for thin film photovoltaics offers improvements in open-circuit voltage, especially when combined with optimal alkali-treatments and certain Ga concentrations. Gallium 183-185 fucosyltransferase 2 Homo sapiens 28-31 33534535-5 2021 First-principles calculations were employed to evaluate the formation energies of alkali-on-group-I defects (where group-I refers to Ag and Cu) in (Ag,Cu)(In,Ga)Se2 as a function of the Ag and Ga contents. Gallium 158-160 fucosyltransferase 2 Homo sapiens 161-164 33582935-8 2021 In the docking studies, RDV and GA exhibited superiority in binding with the crystal structure of Mpro over the other selected molecules in this study. Gallium 32-34 NEWENTRY Severe acute respiratory syndrome-related coronavirus 98-102 31227464-0 2021 Positron Emission Tomography/Computed Tomography with Gallium-68-labeled Prostate-specific Membrane Antigen Detects Relapse After Vascular-targeted Photodynamic Therapy in a Prostate Cancer Model. Gallium 54-61 folate hydrolase 1 Homo sapiens 73-107 33200850-1 2021 The synthesis of a novel mono-anionic phosphino-amide ligand based on a xanthene backbone is reported, together with the corresponding Ga(I) complex, (PON)Ga (PON = 4-(di(2,4,6-trimethylphenyl)phosphino)-5-(2,6-diisopropylanilido)-2,7-di- tert- butyl-9,9-dimethylxanthene). Gallium 135-138 paraoxonase 1 Homo sapiens 151-154 33200850-4 2021 While the donor properties of the PON ligand towards Ga(I) are highly unsymmetrical, oxidation to Ga(III) leads to much stronger coordination of the pendant phosphine as shown by P-Ga distances which are up to 20% shorter. Gallium 53-55 paraoxonase 1 Homo sapiens 34-37 33200850-4 2021 While the donor properties of the PON ligand towards Ga(I) are highly unsymmetrical, oxidation to Ga(III) leads to much stronger coordination of the pendant phosphine as shown by P-Ga distances which are up to 20% shorter. Gallium 98-100 paraoxonase 1 Homo sapiens 34-37 33200850-4 2021 While the donor properties of the PON ligand towards Ga(I) are highly unsymmetrical, oxidation to Ga(III) leads to much stronger coordination of the pendant phosphine as shown by P-Ga distances which are up to 20% shorter. Gallium 98-100 paraoxonase 1 Homo sapiens 34-37 33586406-2 2021 Gallium-68 (68Ga)-DOTA-TATE is widely used for positron emission tomography/computed tomography (PET/CT) imaging of SSTRs and has shown a higher affinity for SSTR2, the most common SSTR subtype found in NETs. Gallium 0-7 somatostatin receptor 2 Homo sapiens 158-163 33127257-11 2021 Our results confirmed that the Foxp3 polymorphism (rs3761548) could influence the predisposition to GA and the serum IL-10, IL-35, and TGF-beta levels. Gallium 100-102 forkhead box P3 Homo sapiens 31-36 33544272-5 2021 Interestingly, loss of GA-5 signal in sub-meningeal white matter was strongly associated with vascular disruption as defined by extravascular fibrinogen leak and by glio-vascular uncoupling, as defined by dissociation of AQP4-positive astrocyte endfeet and CD31-positive blood vessels. Gallium 23-25 fibrinogen beta chain Homo sapiens 142-152 33544272-5 2021 Interestingly, loss of GA-5 signal in sub-meningeal white matter was strongly associated with vascular disruption as defined by extravascular fibrinogen leak and by glio-vascular uncoupling, as defined by dissociation of AQP4-positive astrocyte endfeet and CD31-positive blood vessels. Gallium 23-25 aquaporin 4 Homo sapiens 221-225 33544272-5 2021 Interestingly, loss of GA-5 signal in sub-meningeal white matter was strongly associated with vascular disruption as defined by extravascular fibrinogen leak and by glio-vascular uncoupling, as defined by dissociation of AQP4-positive astrocyte endfeet and CD31-positive blood vessels. Gallium 23-25 platelet and endothelial cell adhesion molecule 1 Homo sapiens 257-261 32979229-3 2021 We included studies that reported the proportion of management change after 68 Ga-PSMA tracers in patients with BCR. Gallium 79-81 folate hydrolase 1 Homo sapiens 82-86 33372372-7 2021 Moreover, GA-GNPs plus radiation arrested the cell cycle of U251 at the S and G2/M phases and triggered apoptotic cell death, which is supported by increased BAX protein levels and decreased expression of BCL-2. Gallium 10-12 BCL2 associated X, apoptosis regulator Homo sapiens 158-161 33372372-7 2021 Moreover, GA-GNPs plus radiation arrested the cell cycle of U251 at the S and G2/M phases and triggered apoptotic cell death, which is supported by increased BAX protein levels and decreased expression of BCL-2. Gallium 10-12 BCL2 apoptosis regulator Homo sapiens 205-210 32989730-3 2021 Tissue specific GA-depletion was achieved by ectopic expression of the GA-inactivating enzyme AtGA2ox2, which is specific for C19 -GAs, and AtGA2ox7, which acts on C20 -GA precursors. Gallium 16-18 gibberellin 2-oxidase Arabidopsis thaliana 94-102 32989730-3 2021 Tissue specific GA-depletion was achieved by ectopic expression of the GA-inactivating enzyme AtGA2ox2, which is specific for C19 -GAs, and AtGA2ox7, which acts on C20 -GA precursors. Gallium 16-18 gibberellin 2-oxidase 7 Arabidopsis thaliana 140-148 32989730-3 2021 Tissue specific GA-depletion was achieved by ectopic expression of the GA-inactivating enzyme AtGA2ox2, which is specific for C19 -GAs, and AtGA2ox7, which acts on C20 -GA precursors. Gallium 71-73 gibberellin 2-oxidase Arabidopsis thaliana 94-102 33501560-6 2021 The present study reports that smokers carrying GA for IL-6 - 596 G/A were at several folds higher risk of developing oral precancerous lesions. Gallium 48-50 interleukin 6 Homo sapiens 55-59 33321470-8 2021 DOTA-PEG2-LRELHLNNN was labelled with Gallium-68 and NOTA- PEG2-LRELHLNNN with aluminium fluoride-18. Gallium 38-45 insulin-like growth factor 2 Mus musculus 5-9 33487334-4 2021 Here we show that miR160 and its target genes ARF10, ARF16 and ARF17 modulate hypocotyl elongation in a light, brassinazole (BRZ, a BR biosynthesis inhibitor), or paclobutrazol (PAC, a GA biosynthesis inhibitor)-dependent manner in Arabidopsis. Gallium 185-187 MIR160a Arabidopsis thaliana 18-24 33487334-4 2021 Here we show that miR160 and its target genes ARF10, ARF16 and ARF17 modulate hypocotyl elongation in a light, brassinazole (BRZ, a BR biosynthesis inhibitor), or paclobutrazol (PAC, a GA biosynthesis inhibitor)-dependent manner in Arabidopsis. Gallium 185-187 auxin response factor 10 Arabidopsis thaliana 46-51 33487334-4 2021 Here we show that miR160 and its target genes ARF10, ARF16 and ARF17 modulate hypocotyl elongation in a light, brassinazole (BRZ, a BR biosynthesis inhibitor), or paclobutrazol (PAC, a GA biosynthesis inhibitor)-dependent manner in Arabidopsis. Gallium 185-187 auxin response factor 16 Arabidopsis thaliana 53-58 33487334-4 2021 Here we show that miR160 and its target genes ARF10, ARF16 and ARF17 modulate hypocotyl elongation in a light, brassinazole (BRZ, a BR biosynthesis inhibitor), or paclobutrazol (PAC, a GA biosynthesis inhibitor)-dependent manner in Arabidopsis. Gallium 185-187 auxin response factor 17 Arabidopsis thaliana 63-68 32980380-0 2021 Comment on: Role of 68-Ga-PSMA-PET/CT in pelvic radiotherapy field definitions for lymph node coverage in prostate cancer patients, by Onal C, et al. Gallium 23-25 folate hydrolase 1 Homo sapiens 26-30 33022877-7 2021 Evidence of a potential intermediate in the formation of "GaOTf" has been isolated in the form of the bimetallic silver(I)/gallium(I) cluster anion [Ag 4 {Ga(OTf) 3 } 4 (micro-Ga) 6 (OTf) 4 ] 2- . Gallium 58-60 POU class 5 homeobox 1 Homo sapiens 170-189 33378193-0 2021 Hydrogen-Bond-Assisted Alignment of [MCu(SeO3)4Cl(H2O)]4- (M = Fe, Ga) Anionic Layers to Form Two Polar Oxychlorides: Pb2MCu(SeO3)4Cl(H2O). Gallium 67-69 mitochondrial calcium uniporter Homo sapiens 37-40 33268452-5 2021 pFD::amiR-PECT1 plants showed increased gibberellin (GA) levels in the SAM, concomitant with the reduction of REPRESSOR OF GA1-3 levels. Gallium 53-55 phosphorylethanolamine cytidylyltransferase 1 Arabidopsis thaliana 10-15 33268452-7 2021 Together, these results suggest that PECT1 also regulates flowering time through a florigen-independent pathway, modulating SVP expression and thus regulating GA production. Gallium 159-161 phosphorylethanolamine cytidylyltransferase 1 Arabidopsis thaliana 37-42 33391421-2 2021 In the present study, we aimed to evaluate the efficacy of a gallium-68 (68Ga)-labeled dimeric cyclic NGR (cNGR) peptide as a new molecular probe that binds to CD13 in vitro and in vivo. Gallium 61-68 reticulon 4 receptor Mus musculus 102-105 33391421-2 2021 In the present study, we aimed to evaluate the efficacy of a gallium-68 (68Ga)-labeled dimeric cyclic NGR (cNGR) peptide as a new molecular probe that binds to CD13 in vitro and in vivo. Gallium 61-68 alanyl (membrane) aminopeptidase Mus musculus 160-164 32845309-3 2020 Here we provide novel evidence of the role of gibberellins (GAs) in the correct control of megagametogenesis and embryo sac development, via the GA-dependent degradation of RGA-LIKE1 (RGL1) in the ovule primordia. Gallium 60-62 RGA-like 1 Arabidopsis thaliana 173-182 32845309-3 2020 Here we provide novel evidence of the role of gibberellins (GAs) in the correct control of megagametogenesis and embryo sac development, via the GA-dependent degradation of RGA-LIKE1 (RGL1) in the ovule primordia. Gallium 60-62 RGA-like 1 Arabidopsis thaliana 184-188 32845309-7 2020 Expression analysis of YPet-rgl1Delta17 coupled to in situ localization of bioactive GAs in ovule primordia led us to propose a mechanism of GA-mediated RGL1 degradation that allows proper embryo sac development. Gallium 85-87 RGA-like 1 Arabidopsis thaliana 153-157 33452929-4 2021 The PIF1-RVE1 complex is a transcription factor that regulates the production of ABA and GA and helps shift the balance to high concentration of ABA and low concentration of GA, which corresponds to a dormant seed state. Gallium 89-91 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 4-8 33452929-4 2021 The PIF1-RVE1 complex is a transcription factor that regulates the production of ABA and GA and helps shift the balance to high concentration of ABA and low concentration of GA, which corresponds to a dormant seed state. Gallium 89-91 Homeodomain-like superfamily protein Arabidopsis thaliana 9-13 33452929-4 2021 The PIF1-RVE1 complex is a transcription factor that regulates the production of ABA and GA and helps shift the balance to high concentration of ABA and low concentration of GA, which corresponds to a dormant seed state. Gallium 174-176 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 4-8 33452929-4 2021 The PIF1-RVE1 complex is a transcription factor that regulates the production of ABA and GA and helps shift the balance to high concentration of ABA and low concentration of GA, which corresponds to a dormant seed state. Gallium 174-176 Homeodomain-like superfamily protein Arabidopsis thaliana 9-13 33376975-4 2021 The NiMoV cathodic catalyst is combined with a NiO anode in alkaline electrolyzer unit thermally connected to synthesized (Ag,Cu) (In,Ga)Se2 ((A)CIGS) PV modules. Gallium 134-136 fucosyltransferase 2 Homo sapiens 137-140 32531840-1 2020 OBJECTIVE: To investigate the diagnostic performance of gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (68 Ga-PSMA PET/CT) in patients with recurrent prostate cancer with regard to the presence of lymph node metastases (LNM) and local recurrences after primary radiotherapy. Gallium 56-63 folate hydrolase 1 Homo sapiens 158-162 33335564-16 2020 TGFbeta-1 was lower in GA than GB. Gallium 23-25 transforming growth factor beta 1 Homo sapiens 0-9 32941400-3 2020 MATERIALS AND METHODS: The primary objective of the study was to compare the autogenerated volumes of the DIL in Ga-68 PSMA PET-CT with the standard volume delineated in mpMRI. Gallium 113-115 folate hydrolase 1 Homo sapiens 119-123 32782128-3 2020 The use of fluorine-18 PSMA-1007 is advantageous, as it is excreted via the hepatobiliary system rather than urinary and the longer half-life of fluorine-18 compared to gallium tracers, allows for PSMA imaging in centres without a gallium generator. Gallium 231-238 folate hydrolase 1 Homo sapiens 23-27 33175494-1 2020 As an emerging route to further lower the production cost, reducing the thickness of Cu(In,Ga)Se2 (CIGS) absorber has drawn substantial attention and has been intensively studied in recent years. Gallium 91-93 fucosyltransferase 2 Homo sapiens 94-97 33173136-0 2020 Evolving evidence on a link between the ZMYM3 exceptionally long GA-STR and human cognition. Gallium 65-67 zinc finger MYM-type containing 3 Homo sapiens 40-45 33136367-6 2020 Here, we report definitive observation of CISS-induced magnetoconductance in vertical heterojunctions of (Ga,Mn)As/AHPA-L molecules/Au, directly verifying spin filtering by the AHPA-L molecules via spin detection by the (Ga,Mn)As. Gallium 106-108 spindlin 1 Homo sapiens 155-159 33136367-6 2020 Here, we report definitive observation of CISS-induced magnetoconductance in vertical heterojunctions of (Ga,Mn)As/AHPA-L molecules/Au, directly verifying spin filtering by the AHPA-L molecules via spin detection by the (Ga,Mn)As. Gallium 106-108 spindlin 1 Homo sapiens 198-202 33136367-6 2020 Here, we report definitive observation of CISS-induced magnetoconductance in vertical heterojunctions of (Ga,Mn)As/AHPA-L molecules/Au, directly verifying spin filtering by the AHPA-L molecules via spin detection by the (Ga,Mn)As. Gallium 221-223 spindlin 1 Homo sapiens 155-159 33173136-2 2020 This exceptionally long GA-STR is located at a complex string of GA-STRs with a human-specific formula across the complex as follows: (GA)8-(GA)4-(GA)6-(GA)32 (ZMYM3-207 ENST00000373998.5). Gallium 24-26 zinc finger MYM-type containing 3 Homo sapiens 160-165 33173136-2 2020 This exceptionally long GA-STR is located at a complex string of GA-STRs with a human-specific formula across the complex as follows: (GA)8-(GA)4-(GA)6-(GA)32 (ZMYM3-207 ENST00000373998.5). Gallium 65-67 zinc finger MYM-type containing 3 Homo sapiens 160-165 33173136-2 2020 This exceptionally long GA-STR is located at a complex string of GA-STRs with a human-specific formula across the complex as follows: (GA)8-(GA)4-(GA)6-(GA)32 (ZMYM3-207 ENST00000373998.5). Gallium 65-67 zinc finger MYM-type containing 3 Homo sapiens 160-165 33173136-2 2020 This exceptionally long GA-STR is located at a complex string of GA-STRs with a human-specific formula across the complex as follows: (GA)8-(GA)4-(GA)6-(GA)32 (ZMYM3-207 ENST00000373998.5). Gallium 65-67 zinc finger MYM-type containing 3 Homo sapiens 160-165 32806319-11 2020 The results for osteogenic differentiation studies (i.e. ALP activity, RunX2 and osteocalcin expression) have indicated that GA-NCs scaffolds hold potential to assist differentiation of mesenchymal stem cells (MSCs) to osteoblast. Gallium 125-127 bone gamma-carboxyglutamate protein Homo sapiens 81-92 33448534-5 2020 This work offers a new route to designing and synthesizing Ga-based drugs, and also reveals that PDIA3 is an important anticancer target. Gallium 59-61 protein disulfide isomerase family A member 3 Homo sapiens 97-102 33163144-9 2020 GA may alleviate DON cytotoxicity via the TNF signaling pathway by downregulating IL-15, CCL5, and other gene expressions. Gallium 0-2 tumor necrosis factor Sus scrofa 42-45 33163144-9 2020 GA may alleviate DON cytotoxicity via the TNF signaling pathway by downregulating IL-15, CCL5, and other gene expressions. Gallium 0-2 interleukin 15 Sus scrofa 82-87 33163144-9 2020 GA may alleviate DON cytotoxicity via the TNF signaling pathway by downregulating IL-15, CCL5, and other gene expressions. Gallium 0-2 C-C motif chemokine 5 Sus scrofa 89-93 33163144-10 2020 These results indicated that GA could alleviate DON-induced oxidative stress, inflammation, and apoptosis via the TNF signaling pathway in IPEC-J2 cells. Gallium 29-31 tumor necrosis factor Sus scrofa 114-117 32887526-4 2020 Among the series of novel radiolabeled neurotensin analogues, Ga-JMV6659 exhibits high hydrophilicity (logD7.4 = -3.41 +- 0.14), affinity in the low nanomolar range towards NTS1 (Kd = 6.29 +- 1.37 nM), good selectivity (Kd NTS1/Kd NTS2 = 35.9) and high NTS1-mediated internalization. Gallium 62-64 neurotensin Homo sapiens 39-50 32887526-4 2020 Among the series of novel radiolabeled neurotensin analogues, Ga-JMV6659 exhibits high hydrophilicity (logD7.4 = -3.41 +- 0.14), affinity in the low nanomolar range towards NTS1 (Kd = 6.29 +- 1.37 nM), good selectivity (Kd NTS1/Kd NTS2 = 35.9) and high NTS1-mediated internalization. Gallium 62-64 neurotensin Homo sapiens 173-177 32887526-4 2020 Among the series of novel radiolabeled neurotensin analogues, Ga-JMV6659 exhibits high hydrophilicity (logD7.4 = -3.41 +- 0.14), affinity in the low nanomolar range towards NTS1 (Kd = 6.29 +- 1.37 nM), good selectivity (Kd NTS1/Kd NTS2 = 35.9) and high NTS1-mediated internalization. Gallium 62-64 neurotensin Homo sapiens 223-227 32887526-4 2020 Among the series of novel radiolabeled neurotensin analogues, Ga-JMV6659 exhibits high hydrophilicity (logD7.4 = -3.41 +- 0.14), affinity in the low nanomolar range towards NTS1 (Kd = 6.29 +- 1.37 nM), good selectivity (Kd NTS1/Kd NTS2 = 35.9) and high NTS1-mediated internalization. Gallium 62-64 neurotensin Homo sapiens 223-227 32887526-5 2020 It has lower efflux and prolonged plasmatic half-life in human plasma compared to the reference compound (Ga-JMV6661 bearing the minimum active fragment of neurotensin and the same linker and chelate than other analogues). Gallium 106-108 neurotensin Homo sapiens 156-167 32718595-4 2020 The maximum swelling ratio (1000.0 %) was optimized at pH 10, 180 min and 25 C. The validity of NFe3O4@Zn(GA)/Starch-Hydrogel for adsorptive removal of Fluvastatin statin drug provided maximum equilibrium adsorption capacity 782.05 mg g-1. Gallium 107-109 nuclear receptor subfamily 2 group F member 2 Homo sapiens 97-101 33026030-1 2020 We present an atomistic theoretical analysis of the electronic and excitonic properties of ultrathin, monolayer thick wurtzite (In,Ga)N embedded in GaN. Gallium 131-133 gigaxonin Homo sapiens 148-151 33017819-0 2020 Hybrid functional investigation of band offsets for non-polar, Ga-polar and Al-polar interfaces in GaN/AlN heterojunction. Gallium 63-65 gigaxonin Homo sapiens 99-102 33049187-7 2020 Currently, fluciclovine and gallium-68 (68Ga) prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) are the NGI approaches with the most favorable combination of availability, specificity, and sensitivity. Gallium 28-35 folate hydrolase 1 Homo sapiens 46-80 33049187-7 2020 Currently, fluciclovine and gallium-68 (68Ga) prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) are the NGI approaches with the most favorable combination of availability, specificity, and sensitivity. Gallium 28-35 folate hydrolase 1 Homo sapiens 82-86 32170347-0 2020 Pharmacokinetic analysis of [68Ga]Ga-DOTA-TOC PET in meningiomas for assessment of in vivo somatostatin receptor subtype 2. Gallium 31-33 somatostatin receptor 2 Homo sapiens 91-122 32170347-1 2020 PURPOSE: DOTA-D-Phe1-Tyr3-octreotide with gallium-68 ([68Ga]Ga-DOTA-TOC) is one of the PET tracers that forms the basis for peptide receptor radionuclide therapy based on somatostatin receptor subtype 2 (SSTR2) expression in meningiomas. Gallium 42-49 somatostatin receptor 2 Homo sapiens 171-202 32170347-1 2020 PURPOSE: DOTA-D-Phe1-Tyr3-octreotide with gallium-68 ([68Ga]Ga-DOTA-TOC) is one of the PET tracers that forms the basis for peptide receptor radionuclide therapy based on somatostatin receptor subtype 2 (SSTR2) expression in meningiomas. Gallium 42-49 somatostatin receptor 2 Homo sapiens 204-209 32945378-0 2020 Gallium ions promote osteoinduction of human and mouse osteoblasts via the TRPM7/Akt signaling pathway. Gallium 0-7 transient receptor potential cation channel, subfamily M, member 7 Mus musculus 75-80 33204347-5 2020 All hip radiographs were carefully selected to show the presence of a GA. Gallium 70-72 hedgehog interacting protein Homo sapiens 4-7 32919042-5 2020 Although granzyme A and granzyme B (GA and GB), the best characterized of the five human granzymes, trigger very distinct apoptotic cascades, they share the ability to directly target the mitochondria. Gallium 36-38 granzyme B Homo sapiens 24-34 32939023-7 2020 According to these results, it can be speculated that the interaction between Hsp70 and calmodulin could be induced under high temperatures and higher GA contents can be obtained at the same time. Gallium 151-153 heat shock protein family A (Hsp70) member 4 Homo sapiens 78-83 32939023-7 2020 According to these results, it can be speculated that the interaction between Hsp70 and calmodulin could be induced under high temperatures and higher GA contents can be obtained at the same time. Gallium 151-153 calmodulin 1 Homo sapiens 88-98 32592330-1 2020 OBJECTIVES: To determine the proportion of solitary rib lesions on pre-treatment 68 Gallium-labelled prostate-specific membrane antigen (PSMA)/CT scans in men with prostate cancer that are malignant and examine any predictive factors. Gallium 84-91 folate hydrolase 1 Homo sapiens 101-135 32592330-1 2020 OBJECTIVES: To determine the proportion of solitary rib lesions on pre-treatment 68 Gallium-labelled prostate-specific membrane antigen (PSMA)/CT scans in men with prostate cancer that are malignant and examine any predictive factors. Gallium 84-91 folate hydrolase 1 Homo sapiens 137-141 32701807-5 2020 Tumor imaging by Ga-prostate-specific membrane antigen (PSMA)-11 PET is mainly used in prostate cancer patients but is also of interest in adenoid cystic carcinoma patients because of high PSMA-ligand uptake in salivary glands. Gallium 17-19 folate hydrolase 1 Homo sapiens 56-60 32707453-9 2020 GA synthesis was also activated by SlIAA9 inhibition through both the early-13-hydroxylation (for GA1 synthesis) and non-13-hydroxylation (GA4) pathways, indicating that fruit set caused by SlIAA9 inhibition was partially mediated by the GA pathway. Gallium 0-2 auxin-responsive protein IAA9 Solanum lycopersicum 35-41 32707453-9 2020 GA synthesis was also activated by SlIAA9 inhibition through both the early-13-hydroxylation (for GA1 synthesis) and non-13-hydroxylation (GA4) pathways, indicating that fruit set caused by SlIAA9 inhibition was partially mediated by the GA pathway. Gallium 0-2 auxin-responsive protein IAA9 Solanum lycopersicum 190-196 32707453-9 2020 GA synthesis was also activated by SlIAA9 inhibition through both the early-13-hydroxylation (for GA1 synthesis) and non-13-hydroxylation (GA4) pathways, indicating that fruit set caused by SlIAA9 inhibition was partially mediated by the GA pathway. Gallium 98-100 auxin-responsive protein IAA9 Solanum lycopersicum 35-41 32707453-10 2020 SlIAA9 inhibition induced the expression of GA inactivation genes as well as GA biosynthesis genes except SlCPS during early parthenocarpic fruit development in tomato. Gallium 44-46 auxin-responsive protein IAA9 Solanum lycopersicum 0-6 32707453-10 2020 SlIAA9 inhibition induced the expression of GA inactivation genes as well as GA biosynthesis genes except SlCPS during early parthenocarpic fruit development in tomato. Gallium 77-79 auxin-responsive protein IAA9 Solanum lycopersicum 0-6 32945378-0 2020 Gallium ions promote osteoinduction of human and mouse osteoblasts via the TRPM7/Akt signaling pathway. Gallium 0-7 thymoma viral proto-oncogene 1 Mus musculus 81-84 32945378-6 2020 Western blotting was also performed to demonstrate that the biological action of Ga ions was closely associated with the transient receptor potential melastatin 7/Akt signaling pathway. Gallium 81-83 AKT serine/threonine kinase 1 Homo sapiens 163-166 32865030-9 2022 The treatment with GA and fosinopril decreased the elevation of serum creatinine, blood urea nitrogen, cystatin C, beta2-microglobulin and loss of total protein in urine in nephrotoxic rats in a dose-dependent manner (p < 0.05). Gallium 19-21 cystatin C Rattus norvegicus 103-113 32865030-9 2022 The treatment with GA and fosinopril decreased the elevation of serum creatinine, blood urea nitrogen, cystatin C, beta2-microglobulin and loss of total protein in urine in nephrotoxic rats in a dose-dependent manner (p < 0.05). Gallium 19-21 beta-2 microglobulin Rattus norvegicus 115-134 32825798-6 2020 Amino acid substitutions at Cys50, Met65 and Met73, but not His72, significantly impaired the binding between CDDP and the GA-30 domain, thereby suggesting the potential CDDP-binding residues in p22phox protein. Gallium 123-125 cytochrome b-245 alpha chain Homo sapiens 195-202 32854201-3 2020 A model compound, [68Ga]Ga-DOTA-AmBz-MVK(Ac)-OH (AmBz: aminomethylbenzoyl), and its derivative, [68Ga]Ga-DOTA-AmBz-MVK(HTK01166)-OH, coupled with the PSMA (prostate-specific membrane antigen)-targeting motif of the previously reported HTK01166 were synthesized and evaluated to determine if they could be recognized and cleaved by the renal brush border enzymes. Gallium 24-27 mevalonate kinase Mus musculus 37-40 33850501-2 2021 Recently, gallium-68 prostate-specific membrane antigen positron-emission tomography computed tomography (68Ga-PSMA PET/CT) has emerged as a better tool for this. Gallium 10-17 folate hydrolase 1 Homo sapiens 111-115 32785323-10 2020 The BZ nanomaterial loaded with GA caused tumor shrinkage as well as disappearance and effectively downregulated Hsp90 expression in tumors in vivo. Gallium 32-34 heat shock protein 90 alpha family class A member 1 Homo sapiens 113-118 32616652-2 2020 In this study, we investigated GA"s effects on Abeta oligomer formation and deposition. Gallium 31-33 amyloid beta (A4) precursor protein Mus musculus 47-52 32938830-6 2020 SAE1 or UBA2 knockdown by siRNA and treatment with GA, an inhibitor of SAE1/UBA2-mediated SUMOylation, resulted in reduced glycolysis, aggressive phenotype, and inflammation. Gallium 51-53 ubiquitin like modifier activating enzyme 2 Homo sapiens 8-12 32758168-1 2020 BACKGROUND: To evaluate the impact of Gallium-68 [68Ga] labeled prostate specific membrane antigen (PSMA) positron emission tomography (PET)/X-ray computed tomography (CT) compared with conventional imaging on staging and clinical management of men evaluated for primary prostate cancer (PCa). Gallium 38-45 folate hydrolase 1 Homo sapiens 64-98 32938830-6 2020 SAE1 or UBA2 knockdown by siRNA and treatment with GA, an inhibitor of SAE1/UBA2-mediated SUMOylation, resulted in reduced glycolysis, aggressive phenotype, and inflammation. Gallium 51-53 SUMO1 activating enzyme subunit 1 Homo sapiens 71-75 32938830-6 2020 SAE1 or UBA2 knockdown by siRNA and treatment with GA, an inhibitor of SAE1/UBA2-mediated SUMOylation, resulted in reduced glycolysis, aggressive phenotype, and inflammation. Gallium 51-53 ubiquitin like modifier activating enzyme 2 Homo sapiens 76-80 32938830-10 2020 Interestingly, GA treatment attenuated the severity of arthritis in mice with collagen-induced arthritis and human TNF-alpha transgenic mice. Gallium 15-17 tumor necrosis factor Homo sapiens 115-124 32863189-1 2021 BACKGROUND: The present analysis aims to compare the impact of 18F-fluorocholine (18F-choline) and gallium-68 prostate-specific membrane antigen (68Ga-PSMA) positron emission tomography (PET)-computed tomography (CT)-guided metastases-directed therapies (MDTs) in patients with castration-sensitive oligorecurrent prostate cancer (PC). Gallium 99-106 folate hydrolase 1 Homo sapiens 110-155 32758168-1 2020 BACKGROUND: To evaluate the impact of Gallium-68 [68Ga] labeled prostate specific membrane antigen (PSMA) positron emission tomography (PET)/X-ray computed tomography (CT) compared with conventional imaging on staging and clinical management of men evaluated for primary prostate cancer (PCa). Gallium 38-45 folate hydrolase 1 Homo sapiens 100-104 32768351-3 2022 Patients with gallium (ga-68 Prostate-specific membrane antigen (PSMA) PET) PSMA PET-CT and multiparametric (mp) prostate MRI performed according to PIRADS v2 criteria in our clinic were included. Gallium 14-21 folate hydrolase 1 Homo sapiens 76-80 32731334-6 2020 The GA degradation gene SlGA2ox2, and the auxin degradation gene SlDAO1, showed significantly increased expression from the mature-green to the breaker stage during tomato fruit ripening, accompanied by decreased endogenous GA and auxin, indicating that SlGA2ox2 and SlDAO1 were responsible for the reduced GA and auxin concentrations. Gallium 4-6 gibberellin 2-oxidase 2 Solanum lycopersicum 24-32 33471679-6 2020 Among those who were treatment-naive, the increase in serum prolactin levels over baseline was greater at 3 months following CPA initiation (mean change 397 +- 335 mIU/L) than following spironolactone (20.1 +- 87 mIU/L) or GA initiation (64.6 +- 268 mIU/L; P = .0002). Gallium 223-225 prolactin Homo sapiens 60-69 32616652-5 2020 Similarly to genistein, GA up-regulated PPARgamma expression and apolipoprotein E (ApoE) efflux in these cells with an efficacy that was comparable with that of its metabolic precursor delta-tocotrienol and higher than those of alpha-tocopherol metabolites. Gallium 24-26 peroxisome proliferator activated receptor gamma Mus musculus 40-49 32616652-5 2020 Similarly to genistein, GA up-regulated PPARgamma expression and apolipoprotein E (ApoE) efflux in these cells with an efficacy that was comparable with that of its metabolic precursor delta-tocotrienol and higher than those of alpha-tocopherol metabolites. Gallium 24-26 apolipoprotein E Mus musculus 65-81 32616652-5 2020 Similarly to genistein, GA up-regulated PPARgamma expression and apolipoprotein E (ApoE) efflux in these cells with an efficacy that was comparable with that of its metabolic precursor delta-tocotrienol and higher than those of alpha-tocopherol metabolites. Gallium 24-26 apolipoprotein E Mus musculus 83-87 32616652-6 2020 Unlike for genistein and the other vitamin E compounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of PPARgamma activity, and specific activation of pregnane X receptor (PXR) was observed together with ApoE and multidrug resistance protein 1 (MDR1) membrane transporter up-regulation in both the mouse astrocytes and brain tissue. Gallium 60-62 apolipoprotein E Mus musculus 86-90 32616652-6 2020 Unlike for genistein and the other vitamin E compounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of PPARgamma activity, and specific activation of pregnane X receptor (PXR) was observed together with ApoE and multidrug resistance protein 1 (MDR1) membrane transporter up-regulation in both the mouse astrocytes and brain tissue. Gallium 60-62 nuclear receptor subfamily 1, group I, member 2 Mus musculus 195-214 32616652-6 2020 Unlike for genistein and the other vitamin E compounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of PPARgamma activity, and specific activation of pregnane X receptor (PXR) was observed together with ApoE and multidrug resistance protein 1 (MDR1) membrane transporter up-regulation in both the mouse astrocytes and brain tissue. Gallium 60-62 nuclear receptor subfamily 1, group I, member 2 Mus musculus 216-219 32616652-6 2020 Unlike for genistein and the other vitamin E compounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of PPARgamma activity, and specific activation of pregnane X receptor (PXR) was observed together with ApoE and multidrug resistance protein 1 (MDR1) membrane transporter up-regulation in both the mouse astrocytes and brain tissue. Gallium 60-62 apolipoprotein E Mus musculus 248-252 32616652-6 2020 Unlike for genistein and the other vitamin E compounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of PPARgamma activity, and specific activation of pregnane X receptor (PXR) was observed together with ApoE and multidrug resistance protein 1 (MDR1) membrane transporter up-regulation in both the mouse astrocytes and brain tissue. Gallium 60-62 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 257-287 32616652-6 2020 Unlike for genistein and the other vitamin E compounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of PPARgamma activity, and specific activation of pregnane X receptor (PXR) was observed together with ApoE and multidrug resistance protein 1 (MDR1) membrane transporter up-regulation in both the mouse astrocytes and brain tissue. Gallium 60-62 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 289-293 32616652-7 2020 These effects of GA were associated with reduced Abeta deposition in the brain of TgCRND8 mice, a transgenic AD model. Gallium 17-19 amyloid beta (A4) precursor protein Mus musculus 49-54 32616652-8 2020 In conclusion, GA holds potential for preventing Abeta oligomerization and deposition in the brain. Gallium 15-17 amyloid beta (A4) precursor protein Mus musculus 49-54 32731334-6 2020 The GA degradation gene SlGA2ox2, and the auxin degradation gene SlDAO1, showed significantly increased expression from the mature-green to the breaker stage during tomato fruit ripening, accompanied by decreased endogenous GA and auxin, indicating that SlGA2ox2 and SlDAO1 were responsible for the reduced GA and auxin concentrations. Gallium 4-6 gibberellin 2-oxidase 2 Solanum lycopersicum 254-262 32731334-6 2020 The GA degradation gene SlGA2ox2, and the auxin degradation gene SlDAO1, showed significantly increased expression from the mature-green to the breaker stage during tomato fruit ripening, accompanied by decreased endogenous GA and auxin, indicating that SlGA2ox2 and SlDAO1 were responsible for the reduced GA and auxin concentrations. Gallium 26-28 gibberellin 2-oxidase 2 Solanum lycopersicum 254-262 32731334-6 2020 The GA degradation gene SlGA2ox2, and the auxin degradation gene SlDAO1, showed significantly increased expression from the mature-green to the breaker stage during tomato fruit ripening, accompanied by decreased endogenous GA and auxin, indicating that SlGA2ox2 and SlDAO1 were responsible for the reduced GA and auxin concentrations. Gallium 26-28 gibberellin 2-oxidase 2 Solanum lycopersicum 254-262 32722545-9 2020 Several molecules, such as glycyrrhizin (GA), have proven effective in reducing diabetic damage to the retina through the inhibition of HMGB1. Gallium 41-43 high mobility group box 1 Homo sapiens 136-141 32774722-5 2020 A significantly decreased risk of CRC was found to be associated with the LEPR rs6588147 polymorphism (GA vs. GG: crude P=0.007 and GA/AA vs. GG: crude P=0.018). Gallium 103-105 leptin receptor Homo sapiens 74-78 32805638-3 2020 [68Ga]Ga-BOT5035 comprising a bicyclic peptide was developed for specific targeting of PDGFR-beta overexpressed in pathological fibrosis. Gallium 6-9 platelet derived growth factor receptor alpha Homo sapiens 87-97 32602515-0 2020 Synthesis and optical properties of a Y3(Al/Ga)5O12:Ce3+,Cr3+,Nd3+ persistent luminescence nanophosphor: a promising near-infrared-II nanoprobe for biological applications. Gallium 44-46 ND3 Gallus gallus 62-65 32602515-8 2020 These results show great promise for Y3(Al/Ga)5O12:Ce3+,Cr3+,Nd3+ nanocrystals as a PLNP for bio-imaging applications with deep penetration depth and a high signal-to-noise ratio. Gallium 43-45 ND3 Gallus gallus 61-64 32742269-5 2020 The contents of GA12 and GA53 were elevated in the mutants due to the disruption of GA20 oxidase, whereas the contents of other GA precursors (GA15, GA24, GA9, GA44, and GA20) were decreased in the mutants, and the accumulation of bioactive GA1 and GA4 was also decreased, contributing to the semidwarf phenotype. Gallium 16-18 gibberellin 20-oxidase 1 Zea mays 84-88 32394269-12 2020 Our findings present important implications that 68 Ga-PSMA PET/CT can replace BS in future practice. Gallium 52-54 folate hydrolase 1 Homo sapiens 55-59 32508222-5 2020 In the case of crosstalk between SA and GA, exogenous GA3 can upregulate biosynthesis of SA and consequently result in rising levels of SA, enhancing plant defense response to environmental abiotic stresses. Gallium 40-42 succinyl-CoA:glutarate-CoA transferase Homo sapiens 54-57 32433170-11 2020 Different b values should be used for different Ga-labeled radiopharmaceuticals such as those targeting GRPR and PSMA receptors. Gallium 48-50 gastrin releasing peptide receptor Homo sapiens 104-108 32433170-11 2020 Different b values should be used for different Ga-labeled radiopharmaceuticals such as those targeting GRPR and PSMA receptors. Gallium 48-50 folate hydrolase 1 Homo sapiens 113-117 32350497-1 2020 Salt metathesis, i.e. the reaction of sodium beta-diketiminate with (AlCp*)4 and GaCp*, respectively, is a valuable pathway to access the respective aluminium(i) and gallium(i) beta-diketiminates I and II. Gallium 166-173 glutaminase Homo sapiens 81-85 32404702-1 2020 Recent case reports and series have demonstrated the usefulness of Ga/F-PSMA PET/CT in restaging recurrent renal cancer after nephrectomy. Gallium 67-69 folate hydrolase 1 Homo sapiens 72-76 33178861-11 2020 Mean ARR2 was 1.5+-1.08, 0.28+-0.40, and 0.42+-0.55 for AA, GA, and GG, respectively (p value= 0.001). Gallium 60-62 arrestin beta 2 Homo sapiens 5-9 32383588-0 2020 Lithium-Doping Effects in Cu(In,Ga)Se2 Thin-Film and Photovoltaic Properties. Gallium 32-34 fucosyltransferase 2 Homo sapiens 35-38 32566816-4 2020 Among them, rare-earth (RE) sulfates RE2(SO4)3 xH2O (RE = Sc, Yb, Y, Dy) show narrower thermal hystereses (less than 50 C), indicating that they have faster reaction rates than the other sulfates M2(SO4)3 xH2O (M = Al, Ga, Fe, In). Gallium 220-222 G protein-coupled receptor 161 Homo sapiens 37-46 32157271-9 2020 Upregulation of GA biosynthetic gene GA3ox1 expression by nitrate in imbibed phyB mutant seeds was diminished when DJC75 was knocked-out. Gallium 16-18 gibberellin 3-oxidase 1 Arabidopsis thaliana 37-43 32157271-9 2020 Upregulation of GA biosynthetic gene GA3ox1 expression by nitrate in imbibed phyB mutant seeds was diminished when DJC75 was knocked-out. Gallium 16-18 Chaperone DnaJ-domain superfamily protein Arabidopsis thaliana 115-120 32179202-8 2020 Pretreatment with GA showed a remarkable decrease in ulcer index, inflammatory cytokines markers, TBARS, protein expression of Bax and Caspase-3 and a significant increase in the activities of endogenous antioxidants, levels of PGE2 and NO, and protein expression of Bcl-2, Nrf2 and HO-1 when compared with ethanol treated groups. Gallium 18-20 BCL2 associated X, apoptosis regulator Rattus norvegicus 127-130 32179202-8 2020 Pretreatment with GA showed a remarkable decrease in ulcer index, inflammatory cytokines markers, TBARS, protein expression of Bax and Caspase-3 and a significant increase in the activities of endogenous antioxidants, levels of PGE2 and NO, and protein expression of Bcl-2, Nrf2 and HO-1 when compared with ethanol treated groups. Gallium 18-20 caspase 3 Rattus norvegicus 135-144 32179202-8 2020 Pretreatment with GA showed a remarkable decrease in ulcer index, inflammatory cytokines markers, TBARS, protein expression of Bax and Caspase-3 and a significant increase in the activities of endogenous antioxidants, levels of PGE2 and NO, and protein expression of Bcl-2, Nrf2 and HO-1 when compared with ethanol treated groups. Gallium 18-20 BCL2, apoptosis regulator Rattus norvegicus 267-272 32179202-8 2020 Pretreatment with GA showed a remarkable decrease in ulcer index, inflammatory cytokines markers, TBARS, protein expression of Bax and Caspase-3 and a significant increase in the activities of endogenous antioxidants, levels of PGE2 and NO, and protein expression of Bcl-2, Nrf2 and HO-1 when compared with ethanol treated groups. Gallium 18-20 NFE2 like bZIP transcription factor 2 Rattus norvegicus 274-278 32179202-8 2020 Pretreatment with GA showed a remarkable decrease in ulcer index, inflammatory cytokines markers, TBARS, protein expression of Bax and Caspase-3 and a significant increase in the activities of endogenous antioxidants, levels of PGE2 and NO, and protein expression of Bcl-2, Nrf2 and HO-1 when compared with ethanol treated groups. Gallium 18-20 heme oxygenase 1 Rattus norvegicus 283-287 32359123-7 2020 Consistently, HMGB1 inhibitor glycyrrhizin acid (GA) decreased the serum level of HMGB1 and rescued EDR impairment partly in db/db mice. Gallium 49-51 high mobility group box 1 Mus musculus 14-19 32359123-7 2020 Consistently, HMGB1 inhibitor glycyrrhizin acid (GA) decreased the serum level of HMGB1 and rescued EDR impairment partly in db/db mice. Gallium 49-51 high mobility group box 1 Mus musculus 82-87 32359123-11 2020 GA as the HMGB1 inhibitor could attenuate EDR impairment in an animal model of diabetes. Gallium 0-2 high mobility group box 1 Mus musculus 10-15 32451447-8 2020 Our data suggest that ligand-dependent inactivation of SMAX1 in Striga and Arabidopsis can bypass GA-dependent germination in these species. Gallium 98-100 Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein Arabidopsis thaliana 55-60 32449086-0 2020 Neuron-specific enolase has potential value as a biomarker for [18F]FDG/[68Ga]Ga-PSMA-11 PET mismatch findings in advanced mCRPC patients. Gallium 75-77 enolase 2 Homo sapiens 0-23 32449086-15 2020 CONCLUSION: We observed a significantly higher absolute serum concentration and a higher relative increase of NSE in advanced mCRPC patients with [18F]FDG-avid and insufficient PSMA expressing metastases ([18F]FDG/[68Ga]Ga-PSMA-11 mismatch findings on PET/CT) in our cohort. Gallium 217-219 enolase 2 Homo sapiens 110-113 32471559-10 2020 Results from ELISA assay revealed that the cumulative release of EPO from the EPO-CS/GP/GA hydrogel reached 67% at 4h, and 94% at 15 days. Gallium 88-90 erythropoietin Homo sapiens 65-68 32471559-11 2020 MTT assay showed that EPO within EPO-CS/GP/GA hydrogel could significantly promote proliferation of BMSCs compared to control group (p<0.001) . Gallium 43-45 erythropoietin Homo sapiens 22-25 32471559-12 2020 Results of RT-qPCR assays demonstrated that the expression of Sp7, Runx2, Col I and Alp were significantly increased from EPO-CS/GP/GA group compared to control group on day 14 (p<0.001). Gallium 132-134 Sp7 transcription factor Homo sapiens 62-65 32471559-12 2020 Results of RT-qPCR assays demonstrated that the expression of Sp7, Runx2, Col I and Alp were significantly increased from EPO-CS/GP/GA group compared to control group on day 14 (p<0.001). Gallium 132-134 RUNX family transcription factor 2 Homo sapiens 67-72 32471559-12 2020 Results of RT-qPCR assays demonstrated that the expression of Sp7, Runx2, Col I and Alp were significantly increased from EPO-CS/GP/GA group compared to control group on day 14 (p<0.001). Gallium 132-134 ATHS Homo sapiens 84-87 32374450-0 2020 Automated Synthesis of 68 Ga/177 Lu-PSMA on the Trasis miniAllinOne. Gallium 26-28 folate hydrolase 1 Homo sapiens 36-40 32471952-4 2020 COP1 enhanced the degradation of normal and GA-insensitive DELLA alleles when coexpressed in Nicotiana benthamiana. Gallium 44-46 COP1 E3 ubiquitin ligase Homo sapiens 0-4 32471952-8 2020 We propose that DELLAs are destabilized not only by the canonical GA-dependent pathway but also by COP1 and that this control is relevant for growth responses to shade and warm temperature. Gallium 66-68 COP1 E3 ubiquitin ligase Homo sapiens 99-103 32582860-3 2020 We synthesized biodegradable, ligand-conjugated nanoparticles [P2Ns-gambogic acid (GA)] targeting CD71. Gallium 83-85 transferrin receptor Mus musculus 98-102 32582860-4 2020 GA conjugation substantially increased nanoparticle association with CD3+ or CD20+ lymphocytes and with intestinal lymphoid tissues. Gallium 0-2 membrane-spanning 4-domains, subfamily A, member 1 Mus musculus 77-81 32582259-16 2020 Together, the results support a novel paradigm in which GA3/6 maintains high levels of GA2ox expression and low levels of GA4 in quiescent AXBs, whereas activation and outgrowth require increased GA1/4 signaling through the rapid reduction of GA deactivation and subsequent GA biosynthesis. Gallium 87-89 succinyl-CoA:glutarate-CoA transferase Homo sapiens 56-61 32250975-7 2020 Data regarding the performance of [Ga]-DOTATATE for detecting ectopic ACTH-secreting tumors remain limited, in part owing to the recent introduction of this imaging modality in clinical practice, and in part because of the low prevalence of ECS. Gallium 35-37 proopiomelanocortin Homo sapiens 70-74 32347002-5 2020 Here, we demonstrate that mobile GA aggregates are present within neurites, evoke a reduction in synaptic vesicle-associated protein 2 (SV2), and alter Ca2+ influx and synaptic vesicle release. Gallium 33-35 synaptic vesicle glycoprotein 2A Homo sapiens 97-134 32477376-12 2020 The expression level of vacuolar Na+/H+ exchanger gene ZmNHX1 and vacuolar proton pump genes ZmVP1-1 and ZmVP2 were upregulated in the zmcps-1 and zmcps-7 plants under salinity, further proving that in vivo GA deficiency enhanced vacuolar Na+ sequestration in zmcps-1 and zmcps-7 leaves cells to avoid Na+ cytotoxicity. Gallium 207-209 regulatory protein viviparous-1 Zea mays 93-100 32347002-5 2020 Here, we demonstrate that mobile GA aggregates are present within neurites, evoke a reduction in synaptic vesicle-associated protein 2 (SV2), and alter Ca2+ influx and synaptic vesicle release. Gallium 33-35 synaptic vesicle glycoprotein 2A Homo sapiens 136-139 32716402-1 2020 OBJECTIVE: We aimed to investigate the correlations between the prostate specific membrane antigen (PSMA) expression parameters of the primary prostate tumor on gallium-68 (68Ga)-PSMA positron emission tomography/computed tomography (PET/CT) with metastatic patterns in patients with Gleason Score (GS) >7 prostate cancer (PCa). Gallium 161-168 folate hydrolase 1 Homo sapiens 64-98 32716402-1 2020 OBJECTIVE: We aimed to investigate the correlations between the prostate specific membrane antigen (PSMA) expression parameters of the primary prostate tumor on gallium-68 (68Ga)-PSMA positron emission tomography/computed tomography (PET/CT) with metastatic patterns in patients with Gleason Score (GS) >7 prostate cancer (PCa). Gallium 161-168 folate hydrolase 1 Homo sapiens 100-104 32716402-1 2020 OBJECTIVE: We aimed to investigate the correlations between the prostate specific membrane antigen (PSMA) expression parameters of the primary prostate tumor on gallium-68 (68Ga)-PSMA positron emission tomography/computed tomography (PET/CT) with metastatic patterns in patients with Gleason Score (GS) >7 prostate cancer (PCa). Gallium 161-168 folate hydrolase 1 Homo sapiens 179-183 32330828-9 2020 LED lamps contain interesting materials, with even higher concentrations than natural ores, such as gold, silver, copper, aluminum, tin and gallium. Gallium 140-147 small integral membrane protein 10 like 2A Homo sapiens 0-3 32391122-7 2020 NMR spectroscopy revealed that gallium binds to IscU, the bacterial scaffold protein for Fe-S cluster assembly and stabilizes its folded state. Gallium 31-38 iron-sulfur cluster assembly enzyme Rattus norvegicus 48-52 32391122-8 2020 Gallium inhibited the rate of in vitro cluster assembly catalyzed by bacterial cysteine desulfurase in a reaction mixture containing IscU, Fe (II), DTT, and L-cysteine. Gallium 0-7 iron-sulfur cluster assembly enzyme Rattus norvegicus 133-137 32322258-6 2020 Furthermore, NO promoted the expression of a gene involved in ABA catabolism (StCYP707A1, encoding ABA 8"-hydroxylase) and inhibited the expression of a gene involved in ABA biosynthesis (StNCED1, encoding 9-cis-epoxycarotenoid dioxygenase), thereby decreasing the ABA content, disrupting the balance between ABA and gibberellin acid (GA), and ultimately inducing dormancy release and tuber sprouting. Gallium 335-337 9-cis-epoxy-carotenoid dioxygenase 1 Solanum tuberosum 188-195 32108699-1 2020 Ga-labeled prostate-specific membrane antigen (PSMA) ligand PET/CT is a rapidly evolving imaging modality for prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 11-45 31957122-1 2020 OBJECTIVES: Primary objectives: To determine the additive value of gallium-68 prostate-specific membrane antigen (PSMA) positron emission topography (PET)/computed tomography (CT) when combined with multiparametric magnetic resonance imaging (mpMRI) detecting clinically significant prostate cancer (csPCa) in men undergoing initial biopsy for suspicion of PCa, and to determine the proportion of men who could have avoided prostate biopsy with positive mpMRI (PI-RADS >=3) but negative PSMA-PET/CT. Gallium 67-74 folate hydrolase 1 Homo sapiens 78-112 31957122-1 2020 OBJECTIVES: Primary objectives: To determine the additive value of gallium-68 prostate-specific membrane antigen (PSMA) positron emission topography (PET)/computed tomography (CT) when combined with multiparametric magnetic resonance imaging (mpMRI) detecting clinically significant prostate cancer (csPCa) in men undergoing initial biopsy for suspicion of PCa, and to determine the proportion of men who could have avoided prostate biopsy with positive mpMRI (PI-RADS >=3) but negative PSMA-PET/CT. Gallium 67-74 folate hydrolase 1 Homo sapiens 114-118 32108699-1 2020 Ga-labeled prostate-specific membrane antigen (PSMA) ligand PET/CT is a rapidly evolving imaging modality for prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 47-51 31951592-4 2020 Targeting GLP-1R with indium-111, technetium-99m or gallium-68 labeled exendin-4 offers a new approach that permits the successful localization of small benign insulinomas. Gallium 52-62 glucagon like peptide 1 receptor Homo sapiens 10-16 30773328-0 2020 Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer-Updated Diagnostic Utility, Sensitivity, Specificity, and Distribution of Prostate-specific Membrane Antigen-avid Lesions: A Systematic Review and Meta-analysis. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-45 30773328-0 2020 Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer-Updated Diagnostic Utility, Sensitivity, Specificity, and Distribution of Prostate-specific Membrane Antigen-avid Lesions: A Systematic Review and Meta-analysis. Gallium 0-7 folate hydrolase 1 Homo sapiens 177-211 30773328-2 2020 Gallium-68 prostate-specific membrane antigen (PSMA) positron emission tomography (PET) has increasingly been utilised globally to assess the local and metastatic burden of prostate cancer, typically in biochemically recurrent or advanced disease. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-45 30773328-2 2020 Gallium-68 prostate-specific membrane antigen (PSMA) positron emission tomography (PET) has increasingly been utilised globally to assess the local and metastatic burden of prostate cancer, typically in biochemically recurrent or advanced disease. Gallium 0-7 folate hydrolase 1 Homo sapiens 47-51 30773328-18 2020 PATIENT SUMMARY: Gallium-68 prostate-specific membrane antigen positron emission tomography is now an established imaging technique that has been developed in response to inadequacies in standard of care imaging modalities to improve the detection of metastatic disease in prostate cancer, particularly in the setting of disease recurrence. Gallium 17-24 folate hydrolase 1 Homo sapiens 28-62 31001922-5 2020 Nevertheless, increasing GA levels in leaf axils by ectopically expressing the GA-biosynthesis enzyme GA20ox2 significantly impaired axillary meristem initiation. Gallium 25-27 gibberellin 20 oxidase 2 Arabidopsis thaliana 102-109 31845408-5 2020 PSMA-11 and DOTA-TOC were radiolabeled with gallium-68 manually as well as on a cassette module system. Gallium 44-54 folate hydrolase 1 Homo sapiens 0-4 31001922-5 2020 Nevertheless, increasing GA levels in leaf axils by ectopically expressing the GA-biosynthesis enzyme GA20ox2 significantly impaired axillary meristem initiation. Gallium 79-81 gibberellin 20 oxidase 2 Arabidopsis thaliana 102-109 31001922-6 2020 Our study demonstrates that DELLA-SPL9-LAS-GA2ox4 defines a core feedback regulatory module that spatially pattern GA content in the leaf axil and precisely control the axillary bud formation in different spatial and temporal. Gallium 43-45 squamosa promoter binding protein-like 9 Arabidopsis thaliana 28-38 32142250-6 2020 The weakened electron phonon coupling phenomenon by Ga doping in PbS is further verified by our first-principles calculations. Gallium 52-54 cholinergic receptor muscarinic 3 Homo sapiens 65-68 32228932-8 2020 The acidic PGA degradation products (GA) did not promote IL-10 production, but inhibited IL-1beta, IL-6 and TNF-alpha production in 7-days" culture significantly. Gallium 12-14 interleukin 1 alpha Mus musculus 89-97 32228932-8 2020 The acidic PGA degradation products (GA) did not promote IL-10 production, but inhibited IL-1beta, IL-6 and TNF-alpha production in 7-days" culture significantly. Gallium 12-14 interleukin 6 Mus musculus 99-103 32228932-8 2020 The acidic PGA degradation products (GA) did not promote IL-10 production, but inhibited IL-1beta, IL-6 and TNF-alpha production in 7-days" culture significantly. Gallium 12-14 tumor necrosis factor Mus musculus 108-117 32201920-4 2020 Molecular imaging using the HER2-targeting Affibody peptide ABY-025 radiolabelled with 68Ga-gallium for PET/CT is currently under investigation as a non-invasive tool for whole-body evaluation of metastatic HER2 expression. Gallium 92-99 erb-b2 receptor tyrosine kinase 2 Homo sapiens 28-32 32440475-6 2020 Encouragingly, the champion PCE achieved for GA-based PSC device (21.32%) is almost 13% or 20% higher than those of the control device or TGA-based device. Gallium 45-47 T-box transcription factor 1 Homo sapiens 138-141 32204508-6 2020 We demonstrated the tumor-suppressive effect of GA, which induced the decrease of PD-L1 expression through binding to EGFR in NSCLC. Gallium 48-50 CD274 molecule Homo sapiens 82-87 32204508-6 2020 We demonstrated the tumor-suppressive effect of GA, which induced the decrease of PD-L1 expression through binding to EGFR in NSCLC. Gallium 48-50 epidermal growth factor receptor Homo sapiens 118-122 32995149-14 2020 The highest circulatory level of ICAM-1 (280.75 pg/mL) was observed among patient having adenine-adenine (AA) mutant homozygous alleles, followed by (272 pg/mL) for guanine-guanine (GG) homozygous alleles, then (245.12 pg/mL) for guanine-adenine (GA) heterozygous alleles. Gallium 247-249 intercellular adhesion molecule 1 Homo sapiens 33-39 31838188-5 2020 MSn fragmentation experiments showed high stability of the AAZTA-PC21 structure mainly due to the pyrazole derivatization of the curcumin keto-enol moiety and a more feasible radiolabelling was noticed both with gallium-68 and scandium-44 mainly due to the AAZTA-chelator properties. Gallium 212-219 moesin Homo sapiens 0-3 31397458-2 2019 This hierarchical homogeneous structure combined the Ga, Ga2O3 and carbon frameworks (from Ga-MOF) to exhibit excellent electrochemical performance. Gallium 53-55 lysine acetyltransferase 8 Homo sapiens 94-97 31524682-1 2020 We present a case of a 19-year-old woman with Ewing sarcoma of the iliac bone in whom Ga-PSMA-HBED-CC PET/CT showed high radiotracer activity in the primary tumor. Gallium 86-88 folate hydrolase 1 Homo sapiens 89-93 31246686-2 2020 We describe herein a case of chronic nodular fasciitis of the left triceps muscle with a low Ga-labeled prostate-specific membrane antigen (PSMA) ligand uptake on PET/CT. Gallium 93-95 folate hydrolase 1 Homo sapiens 104-138 31246686-2 2020 We describe herein a case of chronic nodular fasciitis of the left triceps muscle with a low Ga-labeled prostate-specific membrane antigen (PSMA) ligand uptake on PET/CT. Gallium 93-95 folate hydrolase 1 Homo sapiens 140-144 31529265-1 2020 PURPOSE: The present study is based on a retrospective analysis of Gallium-68 (68Ga)-labelled prostate-specific membrane antigen (68Ga-PSMA I&T) PET/CT performed in newly diagnosed, treatment-naive prostate cancer (PCa) patients prior to definitive treatment. Gallium 67-74 folate hydrolase 1 Homo sapiens 135-139 32435769-14 2020 CONCLUSION: CAPE at 0.05% or 0.01% did not influence ME, MG, or CS, but reduced GA when applied to ASB before acid conditioning. Gallium 80-82 arylsulfatase B Homo sapiens 99-102 31490893-10 2019 CONCLUSIONS: Elevated serum AFP level and CT findings could distinguish GHA and GA with a high degree of accuracy. Gallium 80-82 alpha fetoprotein Homo sapiens 28-31 31689752-1 2019 Gallium-68 prostate-specific membrane antigen positron emission tomography-computed tomography (Ga-68 PSMA PET/CT) is an imaging modality that promises improved sensitivity and specificity of detection of prostate cancer lesions based on their increased uptake of PSMA-based radiotracers. Gallium 0-10 folate hydrolase 1 Homo sapiens 102-106 31689752-1 2019 Gallium-68 prostate-specific membrane antigen positron emission tomography-computed tomography (Ga-68 PSMA PET/CT) is an imaging modality that promises improved sensitivity and specificity of detection of prostate cancer lesions based on their increased uptake of PSMA-based radiotracers. Gallium 0-10 folate hydrolase 1 Homo sapiens 264-268 31502937-1 2019 Background Recent studies have reported the additive value of combined gallium 68 (68Ga)-labeled Glu-urea-Lys (Ahx)-HBED-CC ligand targeting the prostate-specific membrane antigen (PSMA) (hereafter called 68Ga-PSMA-11) PET/MRI for the detection and localization of primary prostate cancer compared with multiparametric MRI. Gallium 71-78 folate hydrolase 1 Homo sapiens 145-179 31502937-1 2019 Background Recent studies have reported the additive value of combined gallium 68 (68Ga)-labeled Glu-urea-Lys (Ahx)-HBED-CC ligand targeting the prostate-specific membrane antigen (PSMA) (hereafter called 68Ga-PSMA-11) PET/MRI for the detection and localization of primary prostate cancer compared with multiparametric MRI. Gallium 71-78 folate hydrolase 1 Homo sapiens 181-185 31502937-13 2019 Conclusion Our results suggest that gallium 68 (68Ga)-labeled Glu-urea-Lys (Ahx)-HBED-CC ligand targeting the prostate-specific membrane antigen (PSMA) (68Ga-PSMA-11) PET/MRI and multiparametric MRI perform similarly for local staging of prostate cancer in patients with intermediate-to-high-risk prostate cancer. Gallium 36-43 folate hydrolase 1 Homo sapiens 110-144 31502937-13 2019 Conclusion Our results suggest that gallium 68 (68Ga)-labeled Glu-urea-Lys (Ahx)-HBED-CC ligand targeting the prostate-specific membrane antigen (PSMA) (68Ga-PSMA-11) PET/MRI and multiparametric MRI perform similarly for local staging of prostate cancer in patients with intermediate-to-high-risk prostate cancer. Gallium 36-43 folate hydrolase 1 Homo sapiens 146-150 31619173-11 2019 The observation that TFL1-like genes are induced quickly in response to GA suggests they may be directly targeted by GA-responsive transcription factors, and offers a potential explanation for the flowering-inhibitory effects of GA in apple. Gallium 72-74 protein TERMINAL FLOWER 1-like Malus domestica 21-25 31619173-11 2019 The observation that TFL1-like genes are induced quickly in response to GA suggests they may be directly targeted by GA-responsive transcription factors, and offers a potential explanation for the flowering-inhibitory effects of GA in apple. Gallium 117-119 protein TERMINAL FLOWER 1-like Malus domestica 21-25 31367787-7 2019 ATF3, DDIT3, CARS, and PPP1R15A appear as possible candidate PD biomarkers for monitoring the progress of GA treatment. Gallium 106-108 activating transcription factor 3 Homo sapiens 0-4 31058693-2 2019 We describe the heterogeneous uptake of fibrous dysplasia of a whole rib on Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT. Gallium 76-78 folate hydrolase 1 Homo sapiens 87-121 31058693-2 2019 We describe the heterogeneous uptake of fibrous dysplasia of a whole rib on Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT. Gallium 76-78 folate hydrolase 1 Homo sapiens 123-127 31058693-4 2019 Ga-PSMA expression in fibrous dysplasia should not automatically be equated with malignant transformation or confused with prostate cancer metastases. Gallium 0-2 folate hydrolase 1 Homo sapiens 3-7 31895261-14 2020 These results may pave the way for GRPR and integrin alphavbeta3 targeted imaging with Ga-labeled molecules and systemic radionuclide treatment with Lu-labeled compounds. Gallium 87-89 gastrin releasing peptide receptor Homo sapiens 35-39 31895261-14 2020 These results may pave the way for GRPR and integrin alphavbeta3 targeted imaging with Ga-labeled molecules and systemic radionuclide treatment with Lu-labeled compounds. Gallium 87-89 integrin subunit alpha V Homo sapiens 44-64 31894630-1 2020 A chemical vapor deposition method is developed for thickness-controlled (one to four layers), uniform, and continuous films of both defective gallium(II) sulfide (GaS): GaS0.87 and stoichiometric GaS. Gallium 143-162 gastrin Homo sapiens 164-167 31348086-2 2020 Positive uptake on PET/CT imaging with Ga-labeled PSMA is noted in a patient with juvenile nasal angiofibroma, and the same is noted to be absent following complete surgical excision. Gallium 39-41 folate hydrolase 1 Homo sapiens 50-54 31720756-7 2020 The -G1639A polymorphism of the VKORC1 gene, when evaluated, based on the recessive inheritance pattern [AA x (GA + GG)], patients with AA genotype exhibited a higher TTR (68.2% versus 62.8%, p = 0.017). Gallium 111-113 vitamin K epoxide reductase complex subunit 1 Homo sapiens 32-38 31714366-1 2020 OBJECTIVE: To assess the diagnostic performance of Gallium-68 prostate-specific membrane antigen PET-computed tomography (Ga-PSMA PET-CT) in primary lymphnodal staging of patients with intermediate-risk and high-risk prostate cancer and to compare it with multiparametric MRI (mp-MRI) whenever available. Gallium 51-61 folate hydrolase 1 Homo sapiens 125-129 31536657-6 2020 Two loss-of-function atper1 mutants, atper1-1 and atper1-2, displayed suppressed primary seed dormancy accompanied with reduced ABA and increased GA contents in seeds. Gallium 146-148 1-cysteine peroxiredoxin 1 Arabidopsis thaliana 21-27 31536657-6 2020 Two loss-of-function atper1 mutants, atper1-1 and atper1-2, displayed suppressed primary seed dormancy accompanied with reduced ABA and increased GA contents in seeds. Gallium 146-148 1-cysteine peroxiredoxin 1 Arabidopsis thaliana 37-58 32779420-8 2020 CONCLUSION: We present two patients with GA-3 and a novel mutation in the SUGCT gene. Gallium 41-44 succinyl-CoA:glutarate-CoA transferase Homo sapiens 74-79 31776413-4 2019 We hypothesized that increasing the negative charge of the gallium-68/chelator complex would reduce hepatic uptake, which could lead to improved contrast of anti-HER3 affibody-based PET-imaging of HER3 expression. Gallium 59-69 erb-b2 receptor tyrosine kinase 3 Homo sapiens 162-166 31776413-4 2019 We hypothesized that increasing the negative charge of the gallium-68/chelator complex would reduce hepatic uptake, which could lead to improved contrast of anti-HER3 affibody-based PET-imaging of HER3 expression. Gallium 59-69 erb-b2 receptor tyrosine kinase 3 Homo sapiens 197-201 31703635-2 2019 METHODS: We genotyped the SLC39A6 rs1050631 in 512 patients who underwent GA resection. Gallium 74-76 solute carrier family 39 member 6 Homo sapiens 26-33 31649469-1 2019 While 68Gallium prostate-specific membrane antigen positron emission tomography/computed tomography (68Ga-PSMA) has demonstrated increasing utility in the evaluation of prostatic carcinoma, it is essential to be aware of false-negative findings. Gallium 6-15 folate hydrolase 1 Homo sapiens 106-110 31107537-8 2019 Likewise, whole human blood was exposed to the positron emitters [18F]FDG and [68Ga]Ga-PSMA-11 in vitro for 24 h with activity concentrations ranging between 5 and 40 MBq/ml. Gallium 81-83 folate hydrolase 1 Homo sapiens 87-91 31522510-0 2019 Synthesis and Photochemical Studies on Gallium and Indium Complexes of DTPA-PEG3-ArN3 for Radiolabeling Antibodies. Gallium 39-46 paternally expressed 3 Homo sapiens 76-80 31485006-2 2019 Using electron paramagnetic resonance, it was found that the Cr3+ ions substitute the trivalent gallium ions. Gallium 96-103 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 61-64 31246685-1 2019 Ga-labeled prostate-specific membrane antigen inhibitors and Ga-labeled gastrin-releasing peptide receptor antagonists showed interesting results for staging biochemically recurrent prostate cancer. Gallium 61-63 gastrin releasing peptide receptor Homo sapiens 72-106 31141284-1 2019 OBJECTIVE: To determine the number of men with 68 gallium-prostate-specific membrane antigen positron emission tomography/computed tomography (68 Ga-PSMA PET/CT) avid metastasis at diagnosis, as most data on 68 Ga-PSMA PET/CT are for the evaluation of recurrent disease after primary treatment and to our knowledge this study is the largest series of primary prostate cancer staging with 68 Ga-PSMA PET/CT. Gallium 50-57 folate hydrolase 1 Homo sapiens 149-153 31141284-1 2019 OBJECTIVE: To determine the number of men with 68 gallium-prostate-specific membrane antigen positron emission tomography/computed tomography (68 Ga-PSMA PET/CT) avid metastasis at diagnosis, as most data on 68 Ga-PSMA PET/CT are for the evaluation of recurrent disease after primary treatment and to our knowledge this study is the largest series of primary prostate cancer staging with 68 Ga-PSMA PET/CT. Gallium 146-148 folate hydrolase 1 Homo sapiens 149-153 31348076-8 2019 Respective values for Ga-PSMA PET/CT were 17.4 +- 9 and 3.3 +- 2.2. Gallium 22-24 folate hydrolase 1 Homo sapiens 25-29 31274560-1 2019 PURPOSE: This pilot study aimed to prove the complementary value of a novel Gallium-labeled heterodimeric peptide, Ga-NOTA-3P-TATE-RGD, in detection and evaluation of tumors with somatostatin receptor subtype 2 or integrin alphavbeta3 overexpression, including non-small cell lung cancer (NSCLC), small-cell lung cancer (SCLC), neuroendocrine tumor (NET), and neuroendocrine carcinoma (NEC). Gallium 76-83 integrin subunit alpha V Homo sapiens 214-234 31283600-1 2019 To assess the role of Gallium-labeled-prostate-specific membrane antigen PET/CT (Ga-PSMA-PET/CT) in risk group definition and radiotherapy planning in the initially planned definitive radiotherapy (RT) for prostate cancer patients. Gallium 22-29 folate hydrolase 1 Homo sapiens 84-88 31206955-9 2019 The GG+GA genotype of CYP2R1 rs12794714 and AA+AG genotype of CYP2R1 rs10766196 were associated with prevalent vitamin D deficiency in children with type 1 diabetes. Gallium 7-9 cytochrome P450 family 2 subfamily R member 1 Homo sapiens 22-28 31361523-9 2019 The ALDH2 variant frequencies were 80.5% with GG, 17.1% with GA, and 2.4% with AA. Gallium 61-63 aldehyde dehydrogenase 2 family member Homo sapiens 4-9 31322254-0 2019 TRIM67 promotes NF-kappaB pathway and cell apoptosis in GA-13315-treated lung cancer cells. Gallium 56-58 tripartite motif containing 67 Homo sapiens 0-6 31322254-14 2019 GA-13315 promoted TRIM67 expression to increase FAS expression and cell apoptosis. Gallium 0-2 tripartite motif containing 67 Homo sapiens 18-24 31322254-15 2019 TRIM67 promoted the processing of NF-kappaB2 into its active form, p52, which then enhanced the NF-kappaB pathway and GA-13315-induced apoptosis. Gallium 118-120 tripartite motif containing 67 Homo sapiens 0-6 31322254-15 2019 TRIM67 promoted the processing of NF-kappaB2 into its active form, p52, which then enhanced the NF-kappaB pathway and GA-13315-induced apoptosis. Gallium 118-120 nuclear factor kappa B subunit 2 Homo sapiens 67-70 31069696-1 2019 OBJECTIVE: The aim of the study was to retrospectively evaluate the recurrence detection rate of Gallium-68-prostate-specific membrane antigen [(68Ga)PSMA] imaging and therapy (I&T) positron emission tomography/computed tomography (PET/CT) at different PSA levels, which enables early detection of patients with radical prostatectomy. Gallium 97-104 folate hydrolase 1 Homo sapiens 150-154 31468235-11 2019 CONCLUSIONS: Results of this retrospective analysis showed that biochemical responses to treatment and [68Ga]Ga-PSMA-11 PET/CT-based responses to treatment differ in one third of metastatic PCa patients. Gallium 106-108 folate hydrolase 1 Homo sapiens 112-116 31353367-4 2019 It is found that substituting Ga atoms in the GaN lattice with lighter atoms (e.g. boron atoms) with 50% concentration near the interface can increase the thermal boundary conductance (TBC) by up to 50%. Gallium 30-32 gigaxonin Homo sapiens 46-49 31274636-2 2019 We describe the incidental detection of a radiation-induced undifferentiated soft-tissue sarcoma with increased uptake on Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT in a prostate cancer patient previously treated with surgery and external-beam radiotherapy. Gallium 122-124 folate hydrolase 1 Homo sapiens 133-167 31230088-1 2019 PURPOSE: Prostate-specific membrane antigen (PSMA) PET/CT is increasingly used in patients with biochemically recurrent prostate cancer (BCR), mostly using gallium-68 (168Ga)-labelled radiotracers. Gallium 156-163 folate hydrolase 1 Homo sapiens 9-43 31230088-1 2019 PURPOSE: Prostate-specific membrane antigen (PSMA) PET/CT is increasingly used in patients with biochemically recurrent prostate cancer (BCR), mostly using gallium-68 (168Ga)-labelled radiotracers. Gallium 156-163 folate hydrolase 1 Homo sapiens 45-49 31084884-3 2019 SOM is reported as the critical factor negatively controls light-irradiation seeds germination by altering Abscisic acid (ABA) and gibberellin acid (GA) biosynthesis. Gallium 149-151 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 0-3 30972933-2 2019 In this study, we aim to describe the trends of use between Gallium-68 prostate-specific membrane antigen ligand (Ga-68 PSMA) PET/computed tomography (PSMA PET/CT) and nuclear medicine bone scan (NMBS) for prostate cancer staging in the first institution in Australia to offer both modalities. Gallium 60-67 folate hydrolase 1 Homo sapiens 120-124 31107410-9 2019 CONCLUSION: The highest significant positive correlation between LN size and SUV was in patients with pelvic and abdominal LN metastases without bone involvement according to the gallium-68 PSMA PET/computed tomography images in our study. Gallium 179-186 folate hydrolase 1 Homo sapiens 190-194 31352698-6 2019 Learning Points: In a young patient with concurrent hypokalemia and uncontrolled hypertension on multiple antihypertensive agents, secondary causes of hypertension should be evaluated.Patients with Cushing"s syndrome can develop an acquired hypercoagulable state leading to spontaneous and postoperative venous thromboembolism.Pulmonary emboli may complicate the imaging of the bronchial carcinoid tumor in ectopic ACTH syndrome.Imaging with Gallium-68 DOTATATE PET/CT scan has the highest sensitivity and specificity in detecting ectopic ACTH-secreting tumors.A combination of various noninvasive biochemical tests can enhance the diagnostic accuracy in differentiating Cushing"s disease from ectopic ACTH syndrome provided they have concordant results. Gallium 442-449 proopiomelanocortin Homo sapiens 415-419 31352698-6 2019 Learning Points: In a young patient with concurrent hypokalemia and uncontrolled hypertension on multiple antihypertensive agents, secondary causes of hypertension should be evaluated.Patients with Cushing"s syndrome can develop an acquired hypercoagulable state leading to spontaneous and postoperative venous thromboembolism.Pulmonary emboli may complicate the imaging of the bronchial carcinoid tumor in ectopic ACTH syndrome.Imaging with Gallium-68 DOTATATE PET/CT scan has the highest sensitivity and specificity in detecting ectopic ACTH-secreting tumors.A combination of various noninvasive biochemical tests can enhance the diagnostic accuracy in differentiating Cushing"s disease from ectopic ACTH syndrome provided they have concordant results. Gallium 442-449 proopiomelanocortin Homo sapiens 539-543 31352698-6 2019 Learning Points: In a young patient with concurrent hypokalemia and uncontrolled hypertension on multiple antihypertensive agents, secondary causes of hypertension should be evaluated.Patients with Cushing"s syndrome can develop an acquired hypercoagulable state leading to spontaneous and postoperative venous thromboembolism.Pulmonary emboli may complicate the imaging of the bronchial carcinoid tumor in ectopic ACTH syndrome.Imaging with Gallium-68 DOTATATE PET/CT scan has the highest sensitivity and specificity in detecting ectopic ACTH-secreting tumors.A combination of various noninvasive biochemical tests can enhance the diagnostic accuracy in differentiating Cushing"s disease from ectopic ACTH syndrome provided they have concordant results. Gallium 442-449 proopiomelanocortin Homo sapiens 539-543 31380832-1 2019 Silver nanowire transparent electrodes have been employed as window layers for Cu(In,Ga)Se2 thin-film solar cells. Gallium 85-87 fucosyltransferase 2 Homo sapiens 88-91 31336871-10 2019 We propose that AtCRK5 may regulate hypocotyl hook formation in Arabidopsis thaliana through the phosphorylation of polar auxin transport (PAT) proteins, the fine tuning of auxin transport, and consequently the coordination of auxin-ethylene-GA levels. Gallium 242-244 cysteine-rich RLK (RECEPTOR-like protein kinase) 5 Arabidopsis thaliana 16-22 31241343-0 2019 Role of Ga Surface Diffusion in the Elongation Mechanism and Optical Properties of Catalyst-Free GaN Nanowires Grown by Molecular Beam Epitaxy. Gallium 8-10 gigaxonin Homo sapiens 97-100 31241343-1 2019 We have shown that both the morphology and elongation mechanism of GaN nanowires homoepitaxially grown by plasma-assisted molecular beam epitaxy (PA-MBE) on a [0001]-oriented GaN nanowire template are strongly affected by the nominal gallium/nitrogen flux ratio as well as by additional Ga flux diffusing from the side walls. Gallium 234-241 gigaxonin Homo sapiens 67-70 31241343-1 2019 We have shown that both the morphology and elongation mechanism of GaN nanowires homoepitaxially grown by plasma-assisted molecular beam epitaxy (PA-MBE) on a [0001]-oriented GaN nanowire template are strongly affected by the nominal gallium/nitrogen flux ratio as well as by additional Ga flux diffusing from the side walls. Gallium 67-69 gigaxonin Homo sapiens 175-178 31177779-0 2019 Novel Insights into Gallium"s Mechanism of Therapeutic Action: A DFT/PCM Study of the Interaction between Ga3+ and Ribonucleotide Reductase Substrates. Gallium 20-27 succinyl-CoA:glutarate-CoA transferase Homo sapiens 106-109 31516365-0 2019 Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography compared with diagnostic computed tomography in relapsed prostate cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-45 31516367-1 2019 Gallium-68 labeled prostate-specific membrane antigen (Ga-68 PSMA) ligand (HBED-CC) is a novel tracer used for prostate cancer imaging. Gallium 0-7 folate hydrolase 1 Homo sapiens 61-65 31042811-1 2019 Regardless of its high positron energy, 68 Ga-labeled PSMA ligands have become standard of care in metabolic prostate cancer imaging. Gallium 43-45 folate hydrolase 1 Homo sapiens 54-58 31274636-2 2019 We describe the incidental detection of a radiation-induced undifferentiated soft-tissue sarcoma with increased uptake on Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT in a prostate cancer patient previously treated with surgery and external-beam radiotherapy. Gallium 122-124 folate hydrolase 1 Homo sapiens 169-173 30892746-4 2019 In the presence of Na metal, the related digallane [L2 Ga-GaL2 ] (2; L2 =dpp-dad=[(2,6-iPr2 C6 H3 )NC(CH3 )]2 ) is converted into the gallium(I) carbene analogue [L2 Ga:]- (2 A), which undergoes a variety of reactions with isocyanate substrates. Gallium 134-141 galectin 2 Homo sapiens 58-62 30985422-9 2019 SUV of tumor lesions in Ga-PSMA-617 PET had high correlation with those in Lu-PSMA-617 (r = 0.915, P < 0.001) and moderate correlation with those in Lu-EB-PSMA-617 (r = 0.611, P = 0.002). Gallium 24-26 folate hydrolase 1 Homo sapiens 27-31 31054157-4 2019 The [68 Ga]Ga-PSMA-617-ME was tested in vitro for its cytotoxicity to HEK293 and PC3 cells. Gallium 8-10 folate hydrolase 1 Homo sapiens 14-18 31054157-6 2019 [68 Ga]Ga-PSMA-617-ME indicated negligible cellular toxicity at different concentrations. Gallium 4-6 folate hydrolase 1 Homo sapiens 10-14 31054157-9 2019 The incorporation of [68 Ga]Ga-PSMA-617 into ME was successfully demonstrated and resulted in a stable nontoxic formulation as evaluated by in vitro and in vivo means. Gallium 25-27 folate hydrolase 1 Homo sapiens 31-35 31117755-3 2019 Detailed electron microscopy investigations indicate that the In and Ga concentrations in the nanowire cores and shells varied along the growth direction of InGaP nanowires. Gallium 69-71 regenerating family member 3 alpha Homo sapiens 157-162 30985422-9 2019 SUV of tumor lesions in Ga-PSMA-617 PET had high correlation with those in Lu-PSMA-617 (r = 0.915, P < 0.001) and moderate correlation with those in Lu-EB-PSMA-617 (r = 0.611, P = 0.002). Gallium 24-26 folate hydrolase 1 Homo sapiens 78-82 30985422-9 2019 SUV of tumor lesions in Ga-PSMA-617 PET had high correlation with those in Lu-PSMA-617 (r = 0.915, P < 0.001) and moderate correlation with those in Lu-EB-PSMA-617 (r = 0.611, P = 0.002). Gallium 24-26 folate hydrolase 1 Homo sapiens 78-82 31127174-5 2019 Based on the first-principles calculations within a density functional theory framework, we demonstrate that disorder (substitutional) by Ga+ ion milling process, which is used to fabricate nanowires, induces local magnetic moments in Bi2Te3 crystal that can lead to spin-dependent scattering of surface and bulk electrons. Gallium 138-140 spindlin 1 Homo sapiens 267-271 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 gastrin releasing peptide Homo sapiens 69-72 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 DNA damage inducible transcript 3 Homo sapiens 105-109 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 DNA damage inducible transcript 3 Homo sapiens 111-135 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 glial cell derived neurotrophic factor Homo sapiens 138-141 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 activating transcription factor 6 Homo sapiens 143-177 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 235-239 31138775-11 2019 GA treatment increased intracellular ROS level, expression levels of GRP (glucose-regulated protein) 78, CHOP (C/EBP-homologous protein), ATF (activating transcription factor) 6 and caspase 12, as well as the phosphorylation levels of PERK (protein kinase R-like ER kinase) and IRE (inositol-requiring enzyme) 1alpha. Gallium 0-2 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 241-272 31025849-5 2019 Interestingly, GA promotes the wound-healing ability on the scratched epithelial cell surfaces via enhancing the cell migrations as also validated by the western blot analysis via expression levels of epithelial beta-catenin and E-cadherin proteins. Gallium 15-17 catenin beta 1 Homo sapiens 212-224 31025849-4 2019 In vitro cell culture experiments demonstrated that the synthesized GA had nontoxic effects on the cell viability (up to 80.35%) even at higher concentrations (10 mg mL-1), as determined via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and lactate dehydrogenase assays using human lung bronchial epithelial cells. Gallium 68-70 L1 cell adhesion molecule Mus musculus 166-170 30928607-0 2019 Location of Recurrence by Gallium-68 PSMA-11 PET Scan in Prostate Cancer Patients Eligible for Salvage Radiotherapy. Gallium 26-33 folate hydrolase 1 Homo sapiens 37-41 30928607-1 2019 OBJECTIVE: To identify locations of recurrence after radical prostatectomy (RP) with prostate-specific antigen (PSA) <2 by Gallium-68 prostate-specific membrane antigen (PSMA)-11 Positron Emission Tomography (PET) imaging, and to determine whether standard nodal radiation fields would cover the location of prostate cancer recurrence. Gallium 126-133 kallikrein related peptidase 3 Homo sapiens 85-116 30928607-1 2019 OBJECTIVE: To identify locations of recurrence after radical prostatectomy (RP) with prostate-specific antigen (PSA) <2 by Gallium-68 prostate-specific membrane antigen (PSMA)-11 Positron Emission Tomography (PET) imaging, and to determine whether standard nodal radiation fields would cover the location of prostate cancer recurrence. Gallium 126-133 folate hydrolase 1 Homo sapiens 173-177 31025849-5 2019 Interestingly, GA promotes the wound-healing ability on the scratched epithelial cell surfaces via enhancing the cell migrations as also validated by the western blot analysis via expression levels of epithelial beta-catenin and E-cadherin proteins. Gallium 15-17 cadherin 1 Homo sapiens 229-239 30990480-0 2019 The shape-controlled synthesis of gallium-palladium (GaPd2) nanomaterials as high-performance electrocatalysts for the hydrogen evolution reaction. Gallium 34-41 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Homo sapiens 53-58 31007012-5 2019 The microscopic mechanism of the phase shift is based on the combined action of the nanogroove as a geometrical defect and the lower spin-wave group velocity in the waveguide under the groove where the magnetization is reduced due to the incorporation of Ga ions during the ion-beam milling. Gallium 255-257 spindlin 1 Homo sapiens 133-137 30888999-3 2019 The aim of this study was to compare the staging and restaging performance of Ga-labeled PSMA and F-choline PET/CT imaging in prostate cancer. Gallium 78-80 folate hydrolase 1 Homo sapiens 89-93 31068831-13 2019 HIGHLIGHTS-MiR-34a rs2666433 polymorphism was associated with an increased risk of ischemic stroke.-The level of miR-34a was significantly up-regulated in ischemic stroke patients compared with controls, and patients with rs2666433 AA genotype had a higher level miR-34a than those with GG+GA genotypes.-Furthermore, increased level of homocysteine was showed in IS patients compared to controls, and in patients carrying the rs2666433AA compared to those carrying the rs2666433 GG+GA. Gallium 290-292 microRNA 34a Homo sapiens 11-18 31068831-13 2019 HIGHLIGHTS-MiR-34a rs2666433 polymorphism was associated with an increased risk of ischemic stroke.-The level of miR-34a was significantly up-regulated in ischemic stroke patients compared with controls, and patients with rs2666433 AA genotype had a higher level miR-34a than those with GG+GA genotypes.-Furthermore, increased level of homocysteine was showed in IS patients compared to controls, and in patients carrying the rs2666433AA compared to those carrying the rs2666433 GG+GA. Gallium 290-292 microRNA 34a Homo sapiens 113-120 30865461-4 2019 A 22-mer sequence targeting miR-15b was conjugated with three different chelators and labeled with gallium-68 (68Ga). Gallium 99-106 microRNA 15b Homo sapiens 28-35 30729655-8 2019 Her serum soluble interleukin-2 receptor and lysozyme level improved in parallel with the enlargement of the mediastinal lymph node and gallium-67 scintigraphy uptake. Gallium 136-143 lysozyme Homo sapiens 45-53 31040600-1 2019 Introduction: We evaluated various morphological and molecular response criteria in metastatic castration-resistant prostate cancer (PCa) patient undergoing peptide receptor radioligand therapy (PRLT) with Lutetium177-prostate-specific membrane antigen (PSMA) by using Gallium 68-PSMA positron-emission tomography-computed tomography (Ga68-PSMA PET-CT). Gallium 269-276 folate hydrolase 1 Homo sapiens 206-252 31040600-1 2019 Introduction: We evaluated various morphological and molecular response criteria in metastatic castration-resistant prostate cancer (PCa) patient undergoing peptide receptor radioligand therapy (PRLT) with Lutetium177-prostate-specific membrane antigen (PSMA) by using Gallium 68-PSMA positron-emission tomography-computed tomography (Ga68-PSMA PET-CT). Gallium 269-276 folate hydrolase 1 Homo sapiens 254-258 30832342-9 2019 Conjugates were stably labeled with gallium-68 and bound specifically to HER3 in vitro and in vivo. Gallium 36-43 erb-b2 receptor tyrosine kinase 3 Homo sapiens 73-77 30747218-4 2019 The results revealed that GA inhibited the proliferation and induced the apoptosis of NSCLC A549 cells in dose- and time-dependent manners, which was associated with upregulated B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) and downregulated Bcl-2. Gallium 26-28 BCL2 apoptosis regulator Homo sapiens 178-195 30917396-3 2019 In the following, we discuss the necessary regulatory environment for the preparation of PSMA PET-radiopharmaceuticals as corresponding investigational medicinal product (IMP) using the example of the prospective multicentre clinical trial (phases-I and -II) "[68Ga]Ga-PSMA-11 in high-risk prostate cancer", and discuss regulatory and organisational issues that need to be taken into account in a decentralized PSMA-PET tracer production from the radiopharmacy perspective. Gallium 263-265 folate hydrolase 1 Homo sapiens 89-93 30747218-4 2019 The results revealed that GA inhibited the proliferation and induced the apoptosis of NSCLC A549 cells in dose- and time-dependent manners, which was associated with upregulated B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) and downregulated Bcl-2. Gallium 26-28 BCL2 apoptosis regulator Homo sapiens 197-202 30747218-4 2019 The results revealed that GA inhibited the proliferation and induced the apoptosis of NSCLC A549 cells in dose- and time-dependent manners, which was associated with upregulated B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) and downregulated Bcl-2. Gallium 26-28 BCL2 associated X, apoptosis regulator Homo sapiens 226-229 30747218-4 2019 The results revealed that GA inhibited the proliferation and induced the apoptosis of NSCLC A549 cells in dose- and time-dependent manners, which was associated with upregulated B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) and downregulated Bcl-2. Gallium 26-28 BCL2 apoptosis regulator Homo sapiens 249-254 30747218-5 2019 Notably, the results also indicated that GA enhanced the anticancer effects of cisplatin in the inhibition of cancer cell proliferation and the induction of cell apoptosis following elevated Bax expression and suppressed Bcl-2 expression. Gallium 41-43 BCL2 associated X, apoptosis regulator Homo sapiens 191-194 30747218-5 2019 Notably, the results also indicated that GA enhanced the anticancer effects of cisplatin in the inhibition of cancer cell proliferation and the induction of cell apoptosis following elevated Bax expression and suppressed Bcl-2 expression. Gallium 41-43 BCL2 apoptosis regulator Homo sapiens 221-226 30911434-0 2019 Diagnostic HER2-binding radiopharmaceutical, [68Ga]Ga-ABY-025, for routine clinical use in breast cancer patients. Gallium 51-54 erb-b2 receptor tyrosine kinase 2 Homo sapiens 11-15 31068831-13 2019 HIGHLIGHTS-MiR-34a rs2666433 polymorphism was associated with an increased risk of ischemic stroke.-The level of miR-34a was significantly up-regulated in ischemic stroke patients compared with controls, and patients with rs2666433 AA genotype had a higher level miR-34a than those with GG+GA genotypes.-Furthermore, increased level of homocysteine was showed in IS patients compared to controls, and in patients carrying the rs2666433AA compared to those carrying the rs2666433 GG+GA. Gallium 290-292 microRNA 34a Homo sapiens 263-270 31068831-13 2019 HIGHLIGHTS-MiR-34a rs2666433 polymorphism was associated with an increased risk of ischemic stroke.-The level of miR-34a was significantly up-regulated in ischemic stroke patients compared with controls, and patients with rs2666433 AA genotype had a higher level miR-34a than those with GG+GA genotypes.-Furthermore, increased level of homocysteine was showed in IS patients compared to controls, and in patients carrying the rs2666433AA compared to those carrying the rs2666433 GG+GA. Gallium 482-484 microRNA 34a Homo sapiens 11-18 31068831-13 2019 HIGHLIGHTS-MiR-34a rs2666433 polymorphism was associated with an increased risk of ischemic stroke.-The level of miR-34a was significantly up-regulated in ischemic stroke patients compared with controls, and patients with rs2666433 AA genotype had a higher level miR-34a than those with GG+GA genotypes.-Furthermore, increased level of homocysteine was showed in IS patients compared to controls, and in patients carrying the rs2666433AA compared to those carrying the rs2666433 GG+GA. Gallium 482-484 microRNA 34a Homo sapiens 113-120 31068831-13 2019 HIGHLIGHTS-MiR-34a rs2666433 polymorphism was associated with an increased risk of ischemic stroke.-The level of miR-34a was significantly up-regulated in ischemic stroke patients compared with controls, and patients with rs2666433 AA genotype had a higher level miR-34a than those with GG+GA genotypes.-Furthermore, increased level of homocysteine was showed in IS patients compared to controls, and in patients carrying the rs2666433AA compared to those carrying the rs2666433 GG+GA. Gallium 482-484 microRNA 34a Homo sapiens 263-270 30859905-0 2019 Gallium nanoparticles along with low-dose gamma radiation modulate TGF-beta/MMP-9 expression in hepatocellular carcinogenesis in rats. Gallium 0-7 matrix metallopeptidase 9 Rattus norvegicus 76-81 30666513-3 2019 In this study, our objective was to evaluate the feasibility of a Gallium-68 (68Ga)-labelled anti-MR nanobody (68Ga-anti-MMR Nb) for the visualization of MR-positive (MR+) macrophages in atherosclerotic plaques of apolipoprotein E-knockout (ApoE-KO) mice. Gallium 66-73 apolipoprotein E Mus musculus 214-230 30238569-5 2019 Conversely, miR319-targeted LANCEOLATE represses floral transition by increasing GA concentrations and inactivating SFT in the leaves and AP1/MC at the shoot apex. Gallium 81-83 microRNA MIR319 Solanum lycopersicum 12-18 30238569-5 2019 Conversely, miR319-targeted LANCEOLATE represses floral transition by increasing GA concentrations and inactivating SFT in the leaves and AP1/MC at the shoot apex. Gallium 81-83 cycloidea Solanum lycopersicum 28-38 30238569-5 2019 Conversely, miR319-targeted LANCEOLATE represses floral transition by increasing GA concentrations and inactivating SFT in the leaves and AP1/MC at the shoot apex. Gallium 81-83 MADS-box transcription factor MADS-MC Solanum lycopersicum 138-141 30651744-8 2019 GA-13315 triggered remarkable apoptosis in A549 cells at the concentration of 25.6 muM and 32 muM (P < 0.05) and activated caspase-3, - 8 and - 9. Gallium 0-2 caspase 3 Homo sapiens 126-148 30395048-0 2019 Can SUVmax values of Ga-68-PSMA PET/CT scan predict the clinically significant prostate cancer? Gallium 21-24 folate hydrolase 1 Homo sapiens 27-31 30411824-3 2019 Here, for the first time, by using a gallium/indium liquid alloy as the precursor, the synthesis of high-quality 2D ternary Ga2 In4 S9 flakes of only a few atomic layers thick ( 2.4 nm for the thinnest samples) through chemical vapor deposition is realized. Gallium 37-44 electron transfer flavoprotein subunit alpha Homo sapiens 124-127 30325820-2 2019 In this case, metastatic areas showing FDG uptake, somatostatin receptor positivity, and PSMA expression are shown in F-FDG PET/CT, Ga-DOTATATE PET/CT, and Ga-PSMA PET/CT in a 70-year-old man with the diagnosis of prostate large cell neuroendocrine carcinoma. Gallium 132-134 folate hydrolase 1 Homo sapiens 89-93 30540600-1 2019 Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for primary staging discovered increased Ga-PSMA uptake in a known anal fistula in a recently diagnosed high-risk prostate cancer patient. Gallium 0-2 folate hydrolase 1 Homo sapiens 39-43 30540600-1 2019 Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for primary staging discovered increased Ga-PSMA uptake in a known anal fistula in a recently diagnosed high-risk prostate cancer patient. Gallium 0-2 folate hydrolase 1 Homo sapiens 101-105 30540600-3 2019 Recently, reports have demonstrated increased Ga-PSMA uptake in different benign inflammatory conditions. Gallium 46-48 folate hydrolase 1 Homo sapiens 49-53 30350010-1 2019 OBJECTIVES: The primary objective was the evaluation of Gallium 68 (68Ga)-prostate-specific membrane antigen (PSMA)-11 positron emission tomography/computed tomography (PET/CT) detection rate, for identifying the site of prostate cancer (PCa) relapse (local vs systemic), stratifying the population according to different clinical stages of biochemical recurrence (BCR). Gallium 56-63 folate hydrolase 1 Homo sapiens 110-114 30273204-2 2018 In this study, we analyzed the contribution of Ga-PSMA-11 PET/CT in staging and therapy management of newly diagnosed PCa. Gallium 47-49 folate hydrolase 1 Homo sapiens 50-54 30273204-3 2018 MATERIALS AND METHODS: A total of 78 patients with biopsy-proven PCa who were referred for Ga-PSMA-11 PET/CT for primary staging were retrospectively analyzed. Gallium 91-93 folate hydrolase 1 Homo sapiens 94-98 30273204-11 2018 Ga-PSMA-11 PET/CT changed the staging in 44 (56.4%) of 78 patients compared with CI. Gallium 0-2 folate hydrolase 1 Homo sapiens 3-7 30356911-7 2018 In addition, the activation of storage reserve mobilization and the enhancement of soluble sugar content and isocitrate lyase (ICL) activity were also induced by GA or H2O2. Gallium 162-164 isocitrate lyase Nicotiana tabacum 109-125 30693042-5 2018 Results: According to the PON2-G148A variant, ALT was found to be significantly correlated with QUICKI (r = -0.616, P = 0.005) and HOMA-BCF (r = 0.573, P = 0.01) in the GA + GG group; however, the correlations were not statistically significant in the AA genotypes. Gallium 169-171 paraoxonase 2 Homo sapiens 26-30 30016556-2 2018 Herein, the reactions of two digallanes bearing alpha-diimine ligands, namely, [L1 Ga-GaL1 ] (1, L1 =dpp-dad=[(2,6-iPr2 C6 H3 )NC(CH3 )]2 ) and [L2 Ga-GaL2 ] (2, L2 =dpp-bian=1,2-[(2,6-iPr2 C6 H3 )NC]2 C10 H6 ), with isothiocyanates are reported. Gallium 83-85 galectin 1 Homo sapiens 86-90 30513758-2 2018 We evaluated a gallium-68 labeled peptide for the detection of MMP-2/9 in atherosclerotic mouse aorta. Gallium 15-22 matrix metallopeptidase 2 Mus musculus 63-70 30588504-0 2018 Pitfalls in Gallium-68 PSMA PET/CT Interpretation-A Pictorial Review. Gallium 12-19 folate hydrolase 1 Homo sapiens 23-27 30588504-1 2018 The novel Gallium-68 prostate-specific membrane antigen (PSMA)-bis [2-hydroxy-5-(carboxyethyl)benzyl] ethylenediamine-diacetic acid positron emission tomography (PET) tracer is increasingly used in the evaluation of prostate cancer, particularly in the detection of recurrent disease. Gallium 10-17 folate hydrolase 1 Homo sapiens 57-61 30126640-4 2018 SEM, XRD, and BET showed that ultrasound-assisted gallium micro-particles are porous, crystalline possessing high surface to volume ratio as compared to that synthesized in the absence of ultrasound. Gallium 50-57 delta/notch like EGF repeat containing Homo sapiens 14-17 30410120-7 2018 Magnetic entropy change DeltaSm ~-18.5 J kg-1 K-1 with relatively concentrated WTI and WTI up to ~60 K with net refrigeration capacity ~240 J kg-1 at 50 kOe are demonstrated in the present Ni-Mn-Ga microwires. Gallium 195-197 keratin 1 Homo sapiens 46-49 30216228-0 2018 Gallium 68-PSMA PET/CT for lesion characterization in suspected cases of prostate carcinoma. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-15 30216228-1 2018 OBJECTIVE: To assess the feasibility of gallium 68 (Ga)-prostate specific membrane antigen (PSMA) PET/computed tomography (CT) to identify patients who truly harbor clinically significant prostate cancer (PCa) in a cohort of patients with clinical and biochemical/radiological suspicion of PCa. Gallium 40-47 folate hydrolase 1 Homo sapiens 92-96 28524719-7 2018 PB1 released from PLGA microdiscs released most slowly, with the most linear release in polymers of 60:40 LA:GA, acid endcap, Mn 15 000-25 000 and 75:25 LA:GA, acid endcap, Mn 45 000-55 000. Gallium 20-22 polybromo 1 Homo sapiens 0-3 28524719-7 2018 PB1 released from PLGA microdiscs released most slowly, with the most linear release in polymers of 60:40 LA:GA, acid endcap, Mn 15 000-25 000 and 75:25 LA:GA, acid endcap, Mn 45 000-55 000. Gallium 109-111 polybromo 1 Homo sapiens 0-3 30356911-7 2018 In addition, the activation of storage reserve mobilization and the enhancement of soluble sugar content and isocitrate lyase (ICL) activity were also induced by GA or H2O2. Gallium 162-164 isocitrate lyase Nicotiana tabacum 127-130 30356911-9 2018 Meanwhile, ICL activity was jointly enhanced by a lower ABA/GA ratio and a higher ROS concentration. Gallium 60-62 isocitrate lyase Nicotiana tabacum 11-14 29945994-3 2018 Well-known mutations of TP53, APC, RNF43, and RPL22 were recurrently detected in synchronous GA/GC pairs. Gallium 93-95 tumor protein p53 Homo sapiens 24-28 30429881-4 2018 NODAGA-conjugates of AMOT ligand, sCD146, were designed, synthesised and radiolabelled with gallium-68. Gallium 92-99 angiomotin Mus musculus 21-25 29945994-3 2018 Well-known mutations of TP53, APC, RNF43, and RPL22 were recurrently detected in synchronous GA/GC pairs. Gallium 93-95 ring finger protein 43 Homo sapiens 35-40 29945994-3 2018 Well-known mutations of TP53, APC, RNF43, and RPL22 were recurrently detected in synchronous GA/GC pairs. Gallium 93-95 ribosomal protein L22 Homo sapiens 46-51 30031856-8 2018 SNPs in TAOK3 showed a significant association with mean MEDD >=800 mg. For rs795484, MEDD values >=800 mg occurred in patients who were GG (7%), GA (18%), and AA (57%) (P = 0.004; Fisher"s exact test); similar results were obtained for rs1277441. Gallium 146-148 TAO kinase 3 Homo sapiens 8-13 30153142-2 2018 However, enhanced uptake on Ga-PSMA PET/CT scan has also been ascribed to other malignant and benign lesions. Gallium 28-30 folate hydrolase 1 Homo sapiens 31-35 30231504-8 2018 Binding of [68Ga]Ga-DFO-ZEGFR:2377 to EGFR-expressing cells in vitro was receptor-specific and proportional to the EGFR expression level. Gallium 14-16 epidermal growth factor receptor Homo sapiens 25-29 30505233-3 2018 Gallium-68 prostate-specific membrane antigen positron emission tomography-computed tomography (68Ga PSMA PET-CT) imaging is a relatively new addition to the imaging modalities in prostate cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 101-105 30231504-8 2018 Binding of [68Ga]Ga-DFO-ZEGFR:2377 to EGFR-expressing cells in vitro was receptor-specific and proportional to the EGFR expression level. Gallium 14-16 epidermal growth factor receptor Homo sapiens 38-42 30231504-9 2018 In vivo saturation experiment demonstrated EGFR-specific accumulation of [68Ga]Ga-DFO-ZEGFR:2377 in A431 xenografts. Gallium 76-78 epidermal growth factor receptor Homo sapiens 43-47 30231504-12 2018 In conclusion, [68Ga]Ga-DFO-ZEGFR:2377 is a promising probe for imaging of EGFR expression. Gallium 18-20 epidermal growth factor receptor Homo sapiens 29-33 30015663-3 2018 Here we present a case involving a 64-year-old man with biochemical recurrence of castrated oligometastatic PCa that presented as solitary testicular metastasis on Ga-PSMA ligand positron emission tomography/computed tomography. Gallium 164-166 folate hydrolase 1 Homo sapiens 167-171 30063051-3 2018 Its utility was demonstrated by the exemplarily chosen access to the mono-arene complex-cations of univalent gallium and indium [M(C6Me6)]+[Al(ORF)4]- (M = Ga and In). Gallium 109-116 cortactin binding protein 2 Homo sapiens 143-148 30036253-1 2018 BACKGROUND: This prospective pilot study investigated the value of Ga-NOTA-RM26, an antagonist targeting gastrin-releasing peptide receptor, in evaluation of breast cancer. Gallium 67-69 gastrin releasing peptide receptor Homo sapiens 105-139 30080189-1 2018 Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT is emerging as new reference standard for imaging of prostate cancer because of superb diagnostic performance in disease staging and recurrence detection. Gallium 0-2 folate hydrolase 1 Homo sapiens 11-45 30080189-1 2018 Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT is emerging as new reference standard for imaging of prostate cancer because of superb diagnostic performance in disease staging and recurrence detection. Gallium 0-2 folate hydrolase 1 Homo sapiens 47-51 30080189-3 2018 We describe the case of a 76-year-old man who underwent Ga-labeled PSMA PET/CT for suspicion of prostate cancer. Gallium 56-58 folate hydrolase 1 Homo sapiens 67-71 30052597-11 2018 There were positive correlations among the expression level of integrin alphavbeta3, microvascular density, and the tumor-to-background ratio derived from Ga-NOTA-PRGD2 PET (P < 0.05). Gallium 155-157 integrin subunit alpha V Homo sapiens 63-83 29847319-2 2018 The Ga-labeled PET tracer targeting the prostate-specific membrane antigen (PSMA, Ga-PSMA-11) is a promising diagnostic approach for staging and restating PCa. Gallium 4-6 folate hydrolase 1 Homo sapiens 40-74 30061395-6 2018 PIF1 also promotes expression of genes encoding ABA-INSENSITIVE5 (ABI5) and DELLA growth-repressor proteins, which act in the ABA and GA signaling pathways, respectively. Gallium 134-136 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 0-4 30061395-6 2018 PIF1 also promotes expression of genes encoding ABA-INSENSITIVE5 (ABI5) and DELLA growth-repressor proteins, which act in the ABA and GA signaling pathways, respectively. Gallium 134-136 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 48-64 30061395-6 2018 PIF1 also promotes expression of genes encoding ABA-INSENSITIVE5 (ABI5) and DELLA growth-repressor proteins, which act in the ABA and GA signaling pathways, respectively. Gallium 134-136 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 66-70 29903915-8 2018 UV cross-linking and immunoprecipitation (CLIP)-Seq revealed that Vps25 specifically recognizes a polypurine (i.e. GA-rich) motif in RNA. Gallium 115-117 vacuolar protein sorting 25 homolog L homeolog Xenopus laevis 66-71 29858124-0 2018 Gallium-68 HBED-CC-PSMA Positron Emission Tomography/Magnetic Resonance Imaging for Prostate Fusion Biopsy. Gallium 0-7 folate hydrolase 1 Homo sapiens 19-23 29893540-6 2018 In particular, in a wide temperature range from 323 to 823 K, the average ZTave value of ~0.9 and the calculated conversion efficiency eta of ~13% are achieved by Ga doping. Gallium 163-165 endothelin receptor type A Homo sapiens 135-138 29978529-2 2018 MATERIALS AND METHODS: A retrospective analysis in 108 consecutive treatment-naive patients with biopsy-proven PCa undergoing Ga-68-PSMA PET/CT (median age, 72 years [range, 49-82 years]) was performed. Gallium 126-128 folate hydrolase 1 Homo sapiens 132-136 30008445-4 2018 The GA-signaling repressor SlDELLA and auxin-signaling components SlIAA9 and SlARF7 repress parthenocarpy, but the underlying mechanism is unknown. Gallium 4-6 auxin-responsive protein IAA9 Solanum lycopersicum 66-72 29786490-0 2018 Gallium 68 PSMA-11 PET/MR Imaging in Patients with Intermediate- or High-Risk Prostate Cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-15 29786490-1 2018 Purpose To report the results of dual-time-point gallium 68 (68Ga) prostate-specific membrane antigen (PSMA)-11 positron emission tomography (PET)/magnetic resonance (MR) imaging prior to prostatectomy in patients with intermediate- or high-risk cancer. Gallium 49-56 folate hydrolase 1 Homo sapiens 67-101 29786490-1 2018 Purpose To report the results of dual-time-point gallium 68 (68Ga) prostate-specific membrane antigen (PSMA)-11 positron emission tomography (PET)/magnetic resonance (MR) imaging prior to prostatectomy in patients with intermediate- or high-risk cancer. Gallium 49-56 folate hydrolase 1 Homo sapiens 103-107 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. Gallium 175-177 cryptochrome 1 Arabidopsis thaliana 31-35 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. Gallium 175-177 cryptochrome-interacting basic-helix-loop-helix 1 Arabidopsis thaliana 84-88 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. Gallium 175-177 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 90-94 31245733-5 2018 Gene expression analysis of accessions Col-0, Ga-0, and Ts-1, showed activated expression of the SPX1/PHR1-mediated gene expression activation pathway acting on galactolipids biosynthesis genes in both Ga-0 and Col-0, but not in Ts-1. Gallium 46-48 SPX domain-containing protein 1 Arabidopsis thaliana 97-101 31245733-5 2018 Gene expression analysis of accessions Col-0, Ga-0, and Ts-1, showed activated expression of the SPX1/PHR1-mediated gene expression activation pathway acting on galactolipids biosynthesis genes in both Ga-0 and Col-0, but not in Ts-1. Gallium 46-48 photolyase 1 Arabidopsis thaliana 102-106 31245733-5 2018 Gene expression analysis of accessions Col-0, Ga-0, and Ts-1, showed activated expression of the SPX1/PHR1-mediated gene expression activation pathway acting on galactolipids biosynthesis genes in both Ga-0 and Col-0, but not in Ts-1. Gallium 202-204 SPX domain-containing protein 1 Arabidopsis thaliana 97-101 31245733-5 2018 Gene expression analysis of accessions Col-0, Ga-0, and Ts-1, showed activated expression of the SPX1/PHR1-mediated gene expression activation pathway acting on galactolipids biosynthesis genes in both Ga-0 and Col-0, but not in Ts-1. Gallium 202-204 photolyase 1 Arabidopsis thaliana 102-106 31245733-6 2018 The activation of the SPX1/PHR1-mediated response pathway can be associated with lower photosynthesis efficiency in Ts-1, compared to Col-0 and Ga-0. Gallium 144-146 SPX domain-containing protein 1 Arabidopsis thaliana 22-26 31245733-6 2018 The activation of the SPX1/PHR1-mediated response pathway can be associated with lower photosynthesis efficiency in Ts-1, compared to Col-0 and Ga-0. Gallium 144-146 photolyase 1 Arabidopsis thaliana 27-31 29688950-1 2018 PET/CT with Ga-labeled prostate-specific membrane antigen (PSMA) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Gallium 12-14 folate hydrolase 1 Homo sapiens 23-57 29688950-1 2018 PET/CT with Ga-labeled prostate-specific membrane antigen (PSMA) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Gallium 12-14 folate hydrolase 1 Homo sapiens 59-63 29688950-3 2018 Apparently, angioneogenesis is the mechanism attributed to increased Ga-PSMA uptake at these sites. Gallium 69-71 folate hydrolase 1 Homo sapiens 72-76 29688950-4 2018 Here we illustrate the utility of Ga-PSMA in 5 nonprostatic malignancies that could open up new possibilities for diagnostics and theranostic concepts with PSMA labeled radioligands in nonprostate tumor entities. Gallium 34-36 folate hydrolase 1 Homo sapiens 37-41 29688950-4 2018 Here we illustrate the utility of Ga-PSMA in 5 nonprostatic malignancies that could open up new possibilities for diagnostics and theranostic concepts with PSMA labeled radioligands in nonprostate tumor entities. Gallium 34-36 folate hydrolase 1 Homo sapiens 156-160 29847319-2 2018 The Ga-labeled PET tracer targeting the prostate-specific membrane antigen (PSMA, Ga-PSMA-11) is a promising diagnostic approach for staging and restating PCa. Gallium 4-6 folate hydrolase 1 Homo sapiens 76-80 29847319-2 2018 The Ga-labeled PET tracer targeting the prostate-specific membrane antigen (PSMA, Ga-PSMA-11) is a promising diagnostic approach for staging and restating PCa. Gallium 4-6 folate hydrolase 1 Homo sapiens 85-89 29665160-1 2018 Reactions of three equivalents of LGa {L=HC[C(Me)N(2,6-iPr2 C6 H3 )]2 } with SbX3 (X=F, Cl, Br, I) proceed with insertion into the Sb-X bond, elimination of LGaX2 , and formation of LGaSbGa(X)L (X=F 1, Cl 2, Br 3, I 4) containing a Ga=Sb double bond. Gallium 35-37 endogenous retrovirus group W member 5 Homo sapiens 202-217 29574486-7 2018 Moreover, the dark-triggered decrease in chlorophyll content, increase in cell membrane leakage, and upregulation of senescence-associated genes were notably impaired in both endogenous GA-decreased mutants ga3ox1/ga3ox2 and ga20ox1/ga20ox2 compared with those in wild-type Col-0. Gallium 186-188 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 225-232 29574486-7 2018 Moreover, the dark-triggered decrease in chlorophyll content, increase in cell membrane leakage, and upregulation of senescence-associated genes were notably impaired in both endogenous GA-decreased mutants ga3ox1/ga3ox2 and ga20ox1/ga20ox2 compared with those in wild-type Col-0. Gallium 186-188 gibberellin 20 oxidase 2 Arabidopsis thaliana 233-240 29572670-1 2018 PURPOSE: To determine the impact of Gallium-68-labled prostate-specific membrane antigen positron-emission tomography/computed tomography ([68Ga]PSMA PET/CT) on radiotherapy planning for primary disease, biochemical cancer relapse, and advanced disease of prostate cancer. Gallium 36-43 folate hydrolase 1 Homo sapiens 145-149 30035428-3 2018 In recent years, there has been an increasing role of Gallium-68 prostate specific membrane antigen (68Ga-PSMA) positron emission tomography/computed tomography (PET/CT) imaging in the management of prostate cancer. Gallium 54-61 folate hydrolase 1 Homo sapiens 106-110 29959846-11 2018 There was an insignificant difference between Ga-tDO and FDG PET regarding diagnostic accuracy (p=0.7). Gallium 46-48 tryptophan 2,3-dioxygenase Homo sapiens 49-52 29863840-4 2018 Based on first-principles calculations of crystallized Si2N2O/GaN slabs, it was confirmed that the NCB state ELP mainly originates from the strong interactions between the dangling bonds of gallium and its vicinal atoms near the interface. Gallium 190-197 nuclear receptor subfamily 5 group A member 1 Homo sapiens 109-112 28836172-0 2018 Organic Gallium Treatment Improves Osteoporotic Fracture Healing Through Affecting the OPG/RANKL Ratio and Expression of Serum Inflammatory Cytokines in Ovariectomized Rats. Gallium 8-15 TNF receptor superfamily member 11B Rattus norvegicus 87-90 29988341-7 2018 The data showed binding of DC-SCRIPT to a GA-rich motif at H3K27ac-marked genomic enhancers that associated with genes encoding MAPK dual-specificity phosphatases (DUSPs). Gallium 42-44 zinc finger protein 366 Homo sapiens 27-36 28836172-0 2018 Organic Gallium Treatment Improves Osteoporotic Fracture Healing Through Affecting the OPG/RANKL Ratio and Expression of Serum Inflammatory Cytokines in Ovariectomized Rats. Gallium 8-15 TNF superfamily member 11 Rattus norvegicus 91-96 28988651-6 2018 Our results indicated that SMAD3 rs1065080 polymorphism was associated with a risk of IAAs in a codominant model (GA vs GG, OR=1.433; 95% CI 1.030-1.994; P=0.032). Gallium 114-116 SMAD family member 3 Homo sapiens 27-32 29578871-5 2018 It revealed peripheral increased uptake of Ga-HBED-CC-PSMA equal to liver uptake. Gallium 43-45 folate hydrolase 1 Homo sapiens 54-58 30003068-10 2018 Analysis of JAK2 V617F (1849 G > T) showed that prevalence of mutation was GG (65.1%), GA (34.9%), and TT (0%), respectively. Gallium 90-92 Janus kinase 2 Homo sapiens 12-16 29592883-1 2018 Gallium, a metal with antineoplastic activity, binds transferrin (Tf) and enters tumor cells via Tf receptor1 (TfR1); it disrupts iron homeostasis leading to cell death. Gallium 0-7 transferrin Homo sapiens 53-64 29592883-1 2018 Gallium, a metal with antineoplastic activity, binds transferrin (Tf) and enters tumor cells via Tf receptor1 (TfR1); it disrupts iron homeostasis leading to cell death. Gallium 0-7 transferrin receptor Homo sapiens 111-115 29592883-6 2018 Tumors in GaM-treated animals displayed an upregulation of TfR1 expression relative to control animals, thus indicating that gallium produced tumor iron deprivation. Gallium 125-132 transferrin receptor Homo sapiens 59-63 29485449-4 2018 We decided to perform Ga-PSMA-HBED-CC PET/CT scan to assess PSMA expression and explore the therapeutic option in view of rising serum calcitonin. Gallium 22-24 folate hydrolase 1 Homo sapiens 25-29 29485449-4 2018 We decided to perform Ga-PSMA-HBED-CC PET/CT scan to assess PSMA expression and explore the therapeutic option in view of rising serum calcitonin. Gallium 22-24 folate hydrolase 1 Homo sapiens 60-64 29405464-3 2018 In contrast, complexes of gallium and indium engage two P(Im)3 ligands resulting in a distorted octahedral geometry for the triel center in compounds of the generic formula [{P(Im)3 }2 M][OTf]3 (M=Ga or In). Gallium 26-33 MAX dimerization protein MGA Homo sapiens 195-199 29529994-8 2018 After the adjustment for possible covariates, the A allele of rs1800849 in UCP3 was significantly associated with prediabetes (aORAA vs GG = 1.68, 95% CI: 1.02-2.78), and the association was also significant under the recessive model (aOR AA vs GA + GG = 1.64, 95% CI: 1.02-2.66). Gallium 245-247 uncoupling protein 3 Homo sapiens 75-79 29028767-1 2018 PURPOSE OF REVIEW: With Gallium (Ga)-prostate-specific membrane antigen (PSMA) PET/computed tomography (CT) as emerging imaging technique offering superior detection rates in biochemical recurrent prostate cancer, salvage lymph node dissection has gained increasing interest in localized oligometastatic prostate cancer. Gallium 24-31 folate hydrolase 1 Homo sapiens 73-77 29028767-1 2018 PURPOSE OF REVIEW: With Gallium (Ga)-prostate-specific membrane antigen (PSMA) PET/computed tomography (CT) as emerging imaging technique offering superior detection rates in biochemical recurrent prostate cancer, salvage lymph node dissection has gained increasing interest in localized oligometastatic prostate cancer. Gallium 24-26 folate hydrolase 1 Homo sapiens 73-77 29400954-6 2018 More importantly, a GA-repressible, nuclear-localized WRKY TF, BrWRKY6, a homologue of the Arabidopsis AtWRKY6, was identified and characterized. Gallium 20-22 WRKY family transcription factor Arabidopsis thaliana 103-110 31245709-10 2018 In these analyses, strong sig2 mutants showed insensitivity to bioactive GA 3, high intracellular levels of hydrogen peroxide (H2O2) indicative of a stress response, and specific defects in photosynthesis, including elevated levels of cyclic electron flow (CEF) and nonphotochemical quenching (NPQ). Gallium 73-75 RNApolymerase sigma subunit 2 Arabidopsis thaliana 26-30 29462927-8 2018 Ga-IMAC interaction with OPN was not selective to phosphorylation, irrespective of salt, as the resin bound OPN from both algal and bacterial sources. Gallium 0-2 secreted phosphoprotein 1 Homo sapiens 25-28 29462927-8 2018 Ga-IMAC interaction with OPN was not selective to phosphorylation, irrespective of salt, as the resin bound OPN from both algal and bacterial sources. Gallium 0-2 secreted phosphoprotein 1 Homo sapiens 108-111 29439481-0 2018 Review of Gallium-68 PSMA PET/CT Imaging in the Management of Prostate Cancer. Gallium 10-17 folate hydrolase 1 Homo sapiens 21-25 28835129-8 2018 The oral administration of GA significantly (p < .001) altered the Fe-NTA induced RCC in rats by inhibition of renal nodules, decolourisation of tissues, tumour promoter marker including thymidine 3[H] incorporation, ornithine decarboxylase, renal parameters and anti-oxidant parameters in serum. Gallium 27-29 ornithine decarboxylase 1 Rattus norvegicus 220-243 29971556-3 2018 Eighty-nine patients referred for gallium-68-PSMA PET/CT for (re)staging of prostate cancer were prospectively included. Gallium 34-41 folate hydrolase 1 Homo sapiens 45-49 29716612-6 2018 On 3 and 14 days after lesion activation, rat brains were assessed using magnetic resonance imaging (MRI), and ex vivo autoradiography was conducted to evaluate the binding of Gallium-68-labelled VAP-1 ligand. Gallium 176-183 amine oxidase, copper containing 3 Rattus norvegicus 196-201 29571066-8 2018 Nature of the metal chelate influenced PSMA binding affinity with IC50 of 233 +- 10 nM for uncomplexed 4, 681 +- 7 nM for Cu-4 and 176 +- 10 nM for Ga-4. Gallium 148-150 folate hydrolase 1 Homo sapiens 39-43 29427770-4 2018 The pooled analyses showed association between carriers of SLC22A1 rs628031A allele (GA + AA vs GG, OR: 0.58, 95% CI: 0.38-0.88, P = 0.011) or rs683369G allele (CG + GG vs CC, OR: 0.64, 95% CI: 0.42-0.96, P = 0.032) and a lower MMR rate. Gallium 85-87 solute carrier family 22 member 1 Homo sapiens 59-66 29684069-6 2018 The substitution of these autophosphorylation sites with Ala enhances the NtCDPK1 overexpression-induced sensitization of seeds to a GA biosynthetic inhibitor during germination. Gallium 133-135 calcium-dependent protein kinase 21-like Nicotiana tabacum 74-81 29401150-4 2018 The uptake of Ga-PSMA in neurocysticercosis is not known and may be attributed to angiogenesis occurring at the periphery of these lesions. Gallium 14-16 folate hydrolase 1 Homo sapiens 17-21 28932900-2 2018 Gallium-68 [68Ga]Pentixafor has recently been introduced for the imaging of atherosclerosis by targeting CXCR4. Gallium 0-7 C-X-C motif chemokine receptor 4 Homo sapiens 105-110 28733706-9 2018 The peptide was radiolabeled with Ga-68 and demonstrated to specifically bind HER3 by in vivo PET imaging. Gallium 34-36 erb-b2 receptor tyrosine kinase 3 Homo sapiens 78-82 29385297-7 2018 We conclude that CYTc levels impinge on the activity of the GA pathway, most likely through changes in mitochondrial energy production. Gallium 60-62 Cytochrome c Arabidopsis thaliana 17-21 29719484-0 2018 A Case of Well-differentiated Hepatocellular Carcinoma Identified on Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography. Gallium 69-76 folate hydrolase 1 Homo sapiens 80-114 29719484-2 2018 To the best of our knowledge, this is the first case reported of an isolated well-differentiated hepatocellular carcinoma (HCC) strongly suspected on gallium-68 (68Ga)-PSMA positron emission tomography/computed tomography (PET/CT), which was not well characterized both on magnetic resonance imaging (MRI) liver with Primovist as well as fluorine-18 (18F)-choline PET/CT. Gallium 150-157 folate hydrolase 1 Homo sapiens 168-172 29728030-3 2018 Different compatibilities of GA, GB and GK could significantly reduce the maximum aggregation rate of PAF-induced platelet aggregation, and the effect was most obvious in combination of the three. Gallium 29-31 PCNA clamp associated factor Rattus norvegicus 102-105 32290954-11 2018 High-B induces the accumulation of GAs, which activates AtTIP5;1 through modulation of the DELLA proteins Repressor of ga1-3 and GA-insensitive, further promoting hypocotyl elongation in A. thaliana. Gallium 35-37 tonoplast intrinsic protein 5;1 Arabidopsis thaliana 56-64 32290954-11 2018 High-B induces the accumulation of GAs, which activates AtTIP5;1 through modulation of the DELLA proteins Repressor of ga1-3 and GA-insensitive, further promoting hypocotyl elongation in A. thaliana. Gallium 35-37 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 119-124 29281247-2 2018 The optimized mass loading of SnS2 along with the addition of nitrogen and sulfur on the surface of GAs results in enhanced electrochemical performance of SnS2@N,S-GA composite. Gallium 100-102 sodium voltage-gated channel alpha subunit 11 Homo sapiens 30-34 29281247-2 2018 The optimized mass loading of SnS2 along with the addition of nitrogen and sulfur on the surface of GAs results in enhanced electrochemical performance of SnS2@N,S-GA composite. Gallium 100-102 sodium voltage-gated channel alpha subunit 11 Homo sapiens 155-159 30016764-16 2018 However, GA could inhibit both Ad-IRF-1 induced HMGB1 release and the increase in the number of LC3 dots. Gallium 9-11 interferon regulatory factor 1 Mus musculus 34-39 30016764-16 2018 However, GA could inhibit both Ad-IRF-1 induced HMGB1 release and the increase in the number of LC3 dots. Gallium 9-11 high mobility group box 1 Mus musculus 48-53 30016764-16 2018 However, GA could inhibit both Ad-IRF-1 induced HMGB1 release and the increase in the number of LC3 dots. Gallium 9-11 microtubule-associated protein 1 light chain 3 alpha Mus musculus 96-99 29126734-1 2018 An asymmetric synthesis of a 3"-deoxy-3"-18F-fluorothymidine (18F-FLT) precursor has been developed wherein the deoxysugar moiety was synthesized using a novel Ga-mediated allylation of (R)-2,3-cyclohexylideneglyceraldehyde as the key step. Gallium 160-162 fms related receptor tyrosine kinase 1 Homo sapiens 66-69 29430118-1 2018 Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (Ga-68 PSMA PET/CT) is a promising diagnostic tool for patients with prostate cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 102-106 29320333-3 2018 Currently, gallium 68 (68Ga)-PSMA-11 (or HBED-PSMA) is the most widely used radiotracer for PSMA positron emission tomography (PET)/computed tomography (CT) or PSMA PET/magnetic resonance (MR) imaging. Gallium 11-18 folate hydrolase 1 Homo sapiens 29-33 31388651-3 2018 Gallium-68 dotatate (ga-68) is an imaging tracer which binds to somatostatin receptor 2 with greater avidity than Indium-111, the tracer used commonly in octreotide scans. Gallium 21-23 somatostatin receptor 2 Homo sapiens 64-87 29133369-9 2018 Taken together, our results demonstrate that WRKY75 may function as a new component of the GA-mediated signaling pathway to positively regulate flowering in Arabidopsis. Gallium 91-93 WRKY DNA-binding protein 75 Arabidopsis thaliana 45-51 29320333-3 2018 Currently, gallium 68 (68Ga)-PSMA-11 (or HBED-PSMA) is the most widely used radiotracer for PSMA positron emission tomography (PET)/computed tomography (CT) or PSMA PET/magnetic resonance (MR) imaging. Gallium 11-18 folate hydrolase 1 Homo sapiens 46-50 29320333-3 2018 Currently, gallium 68 (68Ga)-PSMA-11 (or HBED-PSMA) is the most widely used radiotracer for PSMA positron emission tomography (PET)/computed tomography (CT) or PSMA PET/magnetic resonance (MR) imaging. Gallium 11-18 folate hydrolase 1 Homo sapiens 46-50 29320333-3 2018 Currently, gallium 68 (68Ga)-PSMA-11 (or HBED-PSMA) is the most widely used radiotracer for PSMA positron emission tomography (PET)/computed tomography (CT) or PSMA PET/magnetic resonance (MR) imaging. Gallium 11-18 folate hydrolase 1 Homo sapiens 46-50 29068673-3 2017 The method exhibited favorable adsorption behaviors for gallium with high selectivity, low detection limit (2 ng L-1), and an enrichment factor of 29-fold with the sample throughput of 30 min-1. Gallium 56-63 immunoglobulin kappa variable 1-16 Homo sapiens 113-116 28950199-2 2017 Currently, it mainly features Gallium-68 (68Ga) labeled PSMA ligands, notably [68Ga]Glu-urea-Lys(Ahx)-HBED-CC ([68Ga]-PSMA-11) and [68Ga]DOTAGA-FFK (Sub-KuE termed ([68Ga]PSMA-I&T). Gallium 30-37 folate hydrolase 1 Homo sapiens 56-60 28721585-3 2017 Biochemical characterization indicated that one of them encoded a cytochrome P450 monooxygenase (P450) CYP701A26, which reacted with ent-kaurene to form ent-kaurenoic acid, the key intermediate of GA biosynthesis. Gallium 197-199 cytochrome P450 711A1-like Zea mays 66-95 28548372-0 2017 Initial multicentre experience of 68 gallium-PSMA PET/CT guided robot-assisted salvage lymphadenectomy: acceptable safety profile but oncological benefit appears limited. Gallium 37-44 folate hydrolase 1 Homo sapiens 45-49 28548372-1 2017 OBJECTIVES: To evaluate the safety and short-term oncological outcomes of 68 gallium-labelled prostate-specific membrane antigen (68 Ga-PSMA) positron-emission tomography (PET)/computed tomography (CT)-directed robot-assisted salvage node dissection (RASND) for prostate cancer oligometastatic nodal recurrence. Gallium 77-84 folate hydrolase 1 Homo sapiens 136-140 29241578-9 2017 In conclusion, our results indicate that women who had the AA genotype for LEP-rs7799039 displayed a lower body weight throughout pregnancy compared with GG or GA + GG carriers. Gallium 160-162 leptin Homo sapiens 75-78 28902734-1 2017 A 66-year-old man with history of prostate carcinoma underwent Ga-labeled prostate-specific membrane antigen PET/CT for surveillance of rising prostate-specific antigen. Gallium 63-65 kallikrein related peptidase 3 Homo sapiens 143-168 29216153-4 2017 As a result, linearly temperature-sensitive fluorescence lifetime was achieved in the Cr3+-doped Bi2Ga4O9-Bi2Al4O9 SSs with a high Al/Ga ratio, enabling us to conveniently and accurately determine a temperature with a high relative sensitivity of 2.13-3.26% K-1. Gallium 100-102 keratin 1 Homo sapiens 259-262 29067565-0 2017 Simple, mild, one-step labelling of proteins with gallium-68 using a tris(hydroxypyridinone) bifunctional chelator: a 68Ga-THP-scFv targeting the prostate-specific membrane antigen. Gallium 50-57 immunglobulin heavy chain variable region Homo sapiens 127-131 28972079-0 2017 Histone Deacetylase Is Required for GA-Induced Programmed Cell Death in Maize Aleurone Layers. Gallium 36-38 histone deacetylase Zea mays 0-19 28972079-3 2017 Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. HDAC inhibition prevented GA-induced PCD in embryoless aleurone cells, whereas HAT inhibition resulted in PCD even in the absence of GA. Gallium 286-288 histone deacetylase Zea mays 21-40 28972079-3 2017 Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. HDAC inhibition prevented GA-induced PCD in embryoless aleurone cells, whereas HAT inhibition resulted in PCD even in the absence of GA. Gallium 286-288 histone deacetylase Zea mays 42-46 28972079-3 2017 Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. HDAC inhibition prevented GA-induced PCD in embryoless aleurone cells, whereas HAT inhibition resulted in PCD even in the absence of GA. Gallium 286-288 histone acetyltransferase type B catalytic subunit Zea mays 116-119 28972079-3 2017 Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. HDAC inhibition prevented GA-induced PCD in embryoless aleurone cells, whereas HAT inhibition resulted in PCD even in the absence of GA. Gallium 316-318 histone deacetylase Zea mays 21-40 28972079-3 2017 Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. HDAC inhibition prevented GA-induced PCD in embryoless aleurone cells, whereas HAT inhibition resulted in PCD even in the absence of GA. Gallium 316-318 histone deacetylase Zea mays 42-46 28972079-3 2017 Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. HDAC inhibition prevented GA-induced PCD in embryoless aleurone cells, whereas HAT inhibition resulted in PCD even in the absence of GA. Gallium 316-318 histone acetyltransferase type B catalytic subunit Zea mays 116-119 28972079-7 2017 Taken together, these findings reveal that HDAC activity is required for GA-induced PCD in maize aleurone layers and regulates PCD via the reactive oxygen species-mediated signal transduction pathway. Gallium 73-75 histone deacetylase Zea mays 43-47 28765999-0 2017 A rare case of thymoma first detected on gallium-68 PSMA PET/CT. Gallium 41-48 folate hydrolase 1 Homo sapiens 52-56 29067565-3 2017 A single-chain variable fragment (scFv) of J591, a monoclonal antibody that recognises an external epitope of PSMA, was prepared in order to achieve biokinetics matched to the half-life of gallium-68. Gallium 189-196 immunglobulin heavy chain variable region Homo sapiens 34-38 29067565-7 2017 The THP-mal-J591c-scFv conjugate was labelled with ammonium acetate-buffered gallium-68 from a 68Ge/68Ga generator at room temperature and neutral pH. Gallium 77-84 immunglobulin heavy chain variable region Homo sapiens 18-22 29067565-15 2017 The resultant gallium-68 complex shows high affinity for PSMA and favourable in vivo targeting properties in a xenograft model of PCa. Gallium 14-21 folate hydrolase 1 Homo sapiens 57-61 29109806-3 2017 As the N/Ga flux ratio decreased by increasing Ga flux, the GaN surface trended to a flat morphology with stripes along [11[Formula: see text]0]. Gallium 9-11 gigaxonin Homo sapiens 60-63 29072055-4 2017 Gallium-68 labeled prostatespecific membrane antigen (68Ga-PSMA) PET imaging has now emerged with a higher diagnostic yield. Gallium 0-7 folate hydrolase 1 Homo sapiens 59-63 29109806-3 2017 As the N/Ga flux ratio decreased by increasing Ga flux, the GaN surface trended to a flat morphology with stripes along [11[Formula: see text]0]. Gallium 47-49 gigaxonin Homo sapiens 60-63 28806238-1 2017 Ga-PSMA PET is a rapidly evolving imaging modality for whole-body staging of prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 3-7 29051768-12 2017 This study has shown that amy1 and amy2 from both wheat and barley have similar genomic properties, including exon/intron structures and GA-responsive elements on promoters, but these differ in rice. Gallium 137-139 beta-amylase Tri a 17 Triticum aestivum 26-30 28806260-1 2017 This interesting image illustrates a case of biopsy-proven pulmonary anthracosilicosis, a mixed dust pneumoconiosis, associated with Ga-PSMA-ligand uptake. Gallium 133-135 folate hydrolase 1 Homo sapiens 136-140 28625749-6 2017 The MC1-R specificity of Ga-68- and Sc-44-labeled DOTA-NAPamide was investigated in vitro and in vivo using MC1-R positive (B16-F10) and negative (A375) melanoma cell lines. Gallium 25-27 melanocortin 1 receptor Mus musculus 4-9 28702751-1 2017 The peptide hormone gastrin (Gamide) binds trivalent metal ions, including indium (In), ruthenium (Ru) and gallium (Ga), with high affinity. Gallium 107-114 gastrin Homo sapiens 20-27 28702751-1 2017 The peptide hormone gastrin (Gamide) binds trivalent metal ions, including indium (In), ruthenium (Ru) and gallium (Ga), with high affinity. Gallium 29-31 gastrin Homo sapiens 20-27 29158832-2 2017 The DOTA-conjugate PSMA-617 has proven high potential in PSMA radioligand therapy (PSMA-RLT) of prostate cancer as well as PET imaging when labeled with lutetium-177 and gallium-68 respectively. Gallium 170-177 folate hydrolase 1 Homo sapiens 19-23 28735023-10 2017 Taken together, our results provide compelling evidence that WRKY45 functions as a critical component of the GA-mediated signaling pathway to positively regulate age-triggered leaf senescence. Gallium 109-111 WRKY DNA-binding protein 45 Arabidopsis thaliana 61-67 28589253-0 2017 Early PET imaging with [68]Ga-PSMA-11 increases the detection rate of local recurrence in prostate cancer patients with biochemical recurrence. Gallium 27-29 folate hydrolase 1 Homo sapiens 30-34 28765844-0 2017 A new gallium complex inhibits tumor cell invasion and matrix metalloproteinase MMP-14 expression and activity. Gallium 6-13 matrix metallopeptidase 14 Homo sapiens 80-86 28852469-12 2017 Furthermore, suppression of SIRT1 abated the inhibitory effect of GA on LPS-induced inflammatory response and renal injury. Gallium 66-68 sirtuin 1 Mus musculus 28-33 28813533-8 2017 In dermal fibroblasts, the 18beta-GA derivative induced the phosphorylation of Akt, ERK, and p38. Gallium 34-36 AKT serine/threonine kinase 1 Homo sapiens 79-82 28813533-8 2017 In dermal fibroblasts, the 18beta-GA derivative induced the phosphorylation of Akt, ERK, and p38. Gallium 34-36 mitogen-activated protein kinase 1 Homo sapiens 84-87 29089554-3 2017 Here, we present results of epitaxial magnetocaloric Ni-Mn-Ga-Co thin films on ferroelectric Pb(Mg1/3Nb2/3)0.72Ti0.28O3 (PMN-PT) substrates. Gallium 59-61 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 96-99 28765844-1 2017 In this study, we investigated the effect of [N-(5-chloro-2-hydroxyphenyl)-l-aspartato] chlorogallate (GS2), a new water soluble gallium complex, on cell invasion and on the expression and activity of matrix metalloproteinases (MMPs) in human metastatic HT-1080 fibrosarcoma and MDA-MB 231 breast carcinoma cells. Gallium 129-136 patatin like phospholipase domain containing 4 Homo sapiens 103-106 28813533-8 2017 In dermal fibroblasts, the 18beta-GA derivative induced the phosphorylation of Akt, ERK, and p38. Gallium 34-36 mitogen-activated protein kinase 14 Homo sapiens 93-96 28813533-9 2017 The inhibitor of Akt predominantly suppressed the 18beta-GA derivative-induced expression of aquaporin-3. Gallium 57-59 AKT serine/threonine kinase 1 Homo sapiens 17-20 28504822-9 2017 Similar half-lives have been obtained for the ligand-exchange reactions between the Ga(L)OH complexes and transferrin. Gallium 84-86 transferrin Homo sapiens 106-117 28813533-9 2017 The inhibitor of Akt predominantly suppressed the 18beta-GA derivative-induced expression of aquaporin-3. Gallium 57-59 aquaporin 3 (Gill blood group) Homo sapiens 93-104 28590295-4 2017 Ga-PSMA PET-based imaging is a promising tool for staging and restaging PCa. Gallium 0-2 folate hydrolase 1 Homo sapiens 3-7 28474140-1 2017 PURPOSE: Gallium(68)-labelled prostate-specific membrane antigen (PSMA) radiopharmaceuticals can be used to detect prostate cancer (PCa) cells due the their over expression of PSMA. Gallium 9-16 folate hydrolase 1 Homo sapiens 30-64 28474140-1 2017 PURPOSE: Gallium(68)-labelled prostate-specific membrane antigen (PSMA) radiopharmaceuticals can be used to detect prostate cancer (PCa) cells due the their over expression of PSMA. Gallium 9-16 folate hydrolase 1 Homo sapiens 66-70 28474140-1 2017 PURPOSE: Gallium(68)-labelled prostate-specific membrane antigen (PSMA) radiopharmaceuticals can be used to detect prostate cancer (PCa) cells due the their over expression of PSMA. Gallium 9-16 folate hydrolase 1 Homo sapiens 176-180 28789365-6 2017 In the present study, we found that PPP2R2B expression of H1299 cells is significantly decreased after being treated by GA-13315. Gallium 120-122 protein phosphatase 2 regulatory subunit Bbeta Homo sapiens 36-43 28637832-12 2017 The substitution of these autophosphorylation sites with Ala enhanced the NtCDPK1 overexpression-induced sensitization of seeds to a GA biosynthetic inhibitor during germination. Gallium 133-135 calcium-dependent protein kinase 21-like Nicotiana tabacum 74-81 28938640-8 2017 For LEPR Q223R polymorphism, we observed that the association was only statistically significant in Asians (G versus A: OR = 0.532, P = 0.009; GG versus AA: OR = 0.233, P = 0.002; GA versus AA: OR =0.294, P = 0.006; GG versus AA+AG: OR =0.635, P = 0; GA+GG versus AA: OR = 0.242, P = 0.003), but not in general populations and Caucasians. Gallium 180-182 leptin receptor Homo sapiens 4-8 28644010-3 2017 Gallium could be doped into the oxide film at 200 C when accompanied by an InCA-1 pulse, and no growth of gallium oxide was observed without the simultaneous deposition of indium oxide. Gallium 0-7 inhibitor of CDK, cyclin A1 interacting protein 1 Homo sapiens 76-82 28481787-1 2017 PURPOSE: To investigate the physiologic Ga-PSMA distribution and evaluate focal or diffuse radiotracer uptake in nonprostate cancer malignancies and in incidental findings. Gallium 40-42 folate hydrolase 1 Homo sapiens 43-47 28481787-12 2017 CONCLUSIONS: Physiologic distribution of Ga-PSMA comprises uptake in lacrimal and salivary glands, vocal cords, Waldeyer ring, liver, spleen, and kidneys as well as various parts of the intestine. Gallium 41-43 folate hydrolase 1 Homo sapiens 44-48 28481787-14 2017 Incidental Ga-PSMA uptake can occasionally reveal nonprostate cancer-associated remodeling processes, such as fibrous dysplasia. Gallium 11-13 folate hydrolase 1 Homo sapiens 14-18 28525451-3 2017 In this case report, we demonstrate increased Ga-PMSA uptake on PET/CT in metastases from previously treated colon adenocarcinoma, and it illustrates the importance of histology of suspicious lesions on Ga-PSMA PET/CT. Gallium 46-48 folate hydrolase 1 Homo sapiens 206-210 28537769-6 2017 However, the presence of GA+AA of KSR2-rs7973260 was significantly higher in the metabolic syndrome (MetS), severe hypertriglyceridemia (HTG), and diabetes groups than in control groups (43.7% vs. 37.6%, 46.4% vs. 37.6%, 45.8% vs. 37.9%, respectively). Gallium 25-27 kinase suppressor of ras 2 Homo sapiens 34-38 28680217-3 2017 We describe the case of a patient with bilateral carotid body tumor who underwent a baseline 68 Gallium labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide. Gallium 96-103 mediator complex subunit 25 Homo sapiens 165-172 28530386-1 2017 Electrodepositon of Ga film is very challenging due to the high standard reduction potential (-0.53 V vs SHE for Ga3+). Gallium 20-22 succinyl-CoA:glutarate-CoA transferase Homo sapiens 113-116 28551611-4 2017 The prostate-specific membrane antigen (PSMA) is increasingly investigated as a novel tracer for gallium 68 PET/CT to detect PCa lesions in patients with recurrent disease. Gallium 97-104 folate hydrolase 1 Homo sapiens 4-38 28551611-4 2017 The prostate-specific membrane antigen (PSMA) is increasingly investigated as a novel tracer for gallium 68 PET/CT to detect PCa lesions in patients with recurrent disease. Gallium 97-104 folate hydrolase 1 Homo sapiens 40-44 28685078-2 2017 Gallium-68-labeled prostate specific membrane antigen positron emission tomography/computed tomography (68Ga-PSMA PET/CT) is a novel and promising method for imaging in prostate cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 109-113 28773003-7 2017 The results of GA-based LS-SVM were validated using coupon test data and lap joint component test data with naturally developed fatigue cracks. Gallium 15-17 LAP Homo sapiens 73-76 28649735-3 2017 We, therefore, evaluated in a head-to-head comparison, the diagnostic sensitivity of Ga-68 PSMA PET/CT and Tc-99m PSMA SPECT/CT in patients with prostate cancer. Gallium 85-87 folate hydrolase 1 Homo sapiens 91-95 28138732-0 2017 Limited Value of Ga-68-DOTATOC-PET-CT in Routine Screening of Patients with Multiple Endocrine Neoplasia Type 1. Gallium 17-19 menin 1 Homo sapiens 76-111 28569748-6 2017 Therefore, upon inflammation, endothelial SENP1-mediated SUMOylation drives GA by regulating the synergistic effect of GATA2 and NF-kappaB and consequent endothelial dysfunction. Gallium 76-78 SUMO1/sentrin specific peptidase 1 Mus musculus 42-47 28569748-6 2017 Therefore, upon inflammation, endothelial SENP1-mediated SUMOylation drives GA by regulating the synergistic effect of GATA2 and NF-kappaB and consequent endothelial dysfunction. Gallium 76-78 GATA binding protein 2 Mus musculus 119-124 28569748-6 2017 Therefore, upon inflammation, endothelial SENP1-mediated SUMOylation drives GA by regulating the synergistic effect of GATA2 and NF-kappaB and consequent endothelial dysfunction. Gallium 76-78 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 129-138 28138732-3 2017 The present study evaluated the value of Ga-68-DOTATOC-PET-CT in routine screening of patients with MEN1. Gallium 41-43 menin 1 Homo sapiens 100-104 28447450-0 2017 Band-Bending of Ga-Polar GaN Interfaced with Al2O3 through Ultraviolet/Ozone Treatment. Gallium 16-18 gigaxonin Homo sapiens 25-28 28207974-10 2017 Furthermore, AaMYB1 and AtMYB61 are also essential for gibberellin (GA) biosynthesis and degradation in both species by positively affecting the expression of the enzymes that convert GA9 into the bioactive GA4 as well as the enzymes involved in the degradation of GA4 . Gallium 68-70 myb domain protein 61 Arabidopsis thaliana 24-31 28218997-4 2017 Here we show that the loss of WOX14 function phenocopies some traits of GA-deficient mutants that can be complemented by exogenous GA application, whereas WOX14 overexpression stimulates the expression of GA3ox anabolism genes and represses GA2ox catabolism genes, promoting the accumulation of bioactive GA. More importantly, our data clearly indicate that WOX14 but not WOX4 promotes vascular cell differentiation and lignification in inflorescence stems of Arabidopsis. Gallium 72-74 WUSCHEL related homeobox 14 Arabidopsis thaliana 30-35 28218997-4 2017 Here we show that the loss of WOX14 function phenocopies some traits of GA-deficient mutants that can be complemented by exogenous GA application, whereas WOX14 overexpression stimulates the expression of GA3ox anabolism genes and represses GA2ox catabolism genes, promoting the accumulation of bioactive GA. More importantly, our data clearly indicate that WOX14 but not WOX4 promotes vascular cell differentiation and lignification in inflorescence stems of Arabidopsis. Gallium 72-74 GA requiring 3 Arabidopsis thaliana 205-208 28218997-4 2017 Here we show that the loss of WOX14 function phenocopies some traits of GA-deficient mutants that can be complemented by exogenous GA application, whereas WOX14 overexpression stimulates the expression of GA3ox anabolism genes and represses GA2ox catabolism genes, promoting the accumulation of bioactive GA. More importantly, our data clearly indicate that WOX14 but not WOX4 promotes vascular cell differentiation and lignification in inflorescence stems of Arabidopsis. Gallium 72-74 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 241-244 28218997-4 2017 Here we show that the loss of WOX14 function phenocopies some traits of GA-deficient mutants that can be complemented by exogenous GA application, whereas WOX14 overexpression stimulates the expression of GA3ox anabolism genes and represses GA2ox catabolism genes, promoting the accumulation of bioactive GA. More importantly, our data clearly indicate that WOX14 but not WOX4 promotes vascular cell differentiation and lignification in inflorescence stems of Arabidopsis. Gallium 72-74 WUSCHEL related homeobox 4 Arabidopsis thaliana 372-376 28298088-2 2017 The gate sensing surface of the IS-TGT is transparent in a solution because a transparent amorphous oxide semiconductor composed of amorphous In-Ga-Zn-oxide (a-IGZO) with a thin SiO2 film gate that includes an indium tin oxide (ITO) film as the source and drain electrodes is utilized. Gallium 145-148 queuine tRNA-ribosyltransferase catalytic subunit 1 Homo sapiens 35-38 28529777-0 2017 Crystal structures of titanium-aluminium and -gallium complexes bearing two mu2 -CH3 units. Gallium 45-53 adaptor related protein complex 1 subunit mu 2 Homo sapiens 76-79 28533638-0 2017 Clinical Utility of Gallium-68 PSMA PET/CT Scan for Prostate Cancer. Gallium 20-27 folate hydrolase 1 Homo sapiens 31-35 28267450-0 2017 Imaging of Prostate Cancer Using Gallium-68-Labeled Bombesin. Gallium 33-40 gastrin releasing peptide Homo sapiens 52-60 28267455-0 2017 Gallium-68 Prostate-Specific Membrane Antigen PET Imaging. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-45 28267455-1 2017 The role of gallium-68 (68Ga) prostate-specific membrane antigen (PSMA) PET imaging is evolving and finding its place in the imaging armamentarium for prostate cancer (PCa). Gallium 12-19 folate hydrolase 1 Homo sapiens 30-64 28267455-1 2017 The role of gallium-68 (68Ga) prostate-specific membrane antigen (PSMA) PET imaging is evolving and finding its place in the imaging armamentarium for prostate cancer (PCa). Gallium 12-19 folate hydrolase 1 Homo sapiens 66-70 28140362-3 2017 Here, we report the first gallium-catalyzed hydride vapor phase epitaxy growth of long (more than 10 mum) GaAs nanowires on Si(111) substrates with a high integrated growth rate up to 60 mum h-1 and pure zincblende crystal structure. Gallium 26-33 H1.5 linker histone, cluster member Homo sapiens 191-194 28326087-6 2017 The fact that AtJUB1 exerts an inhibitory effect on the GA/BR biosynthesis and PIF4 genes but acts as a direct activator of DELLA genes in both, Arabidopsis and tomato, strongly supports the model that the molecular constituents of the JUNGBRUNNEN1 growth control module are considerably conserved across species. Gallium 56-58 NAC domain containing protein 42 Arabidopsis thaliana 14-20 28262790-4 2017 Here, we use Ga-doping to relocate the Fermi energy in NbP sufficiently close to the W2 Weyl points, for which the different Fermi surfaces are verified by resultant quantum oscillations. Gallium 13-15 NUBP iron-sulfur cluster assembly factor 1, cytosolic Homo sapiens 55-58 27550154-6 2017 Correlation analysis showed that trace elements Mn, Fe, Ni, Ga, Se, Sr, Cs, U in water and Co, Ni, Cu, Se, U in feed were significantly correlated with those in milk (p < 0.05). Gallium 60-62 Weaning weight-maternal milk Bos taurus 161-165 27891614-8 2017 However, even after the floral transition, ER and ERL1 prevented precocious initiation of the GA-mediated fiber formation. Gallium 94-96 ERECTA-like 1 Arabidopsis thaliana 50-54 27431973-1 2017 Ga-68-labeled radiotracers, particularly used for the detection of neuroendocrine tumors by means of Ga-68-DOTA-TATE or -DOTA-TOC or for the diagnosis of prostate cancer by means of Ga-68-labeled antigens (Ga 68-PSMA), become increasingly important. Gallium 0-2 folate hydrolase 1 Homo sapiens 212-216 32264629-1 2017 In this paper, we report the fabrication of an antibacterial material, Ga-doped C-dots on Ga nanoparticles (Ga@C-dots@Ga NPs), which is deposited on a glass substrate for neural growth. Gallium 71-73 glutaminase Homo sapiens 108-112 32264629-2 2017 A one-step sonochemical process is applied for the simultaneous fabrication and coating of Ga@C-dots@Ga NPs using PEG 400 and molten gallium. Gallium 133-140 glutaminase Homo sapiens 91-95 27941377-1 2017 The potential applications of Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT in the imaging of prostate cancer are now well established. Gallium 30-32 folate hydrolase 1 Homo sapiens 41-75 27177359-6 2017 TGF-beta-induced morphologic changes from epithelial to mesenchymal cells and induction of invasion and migration were reversed by GA C15:1. Gallium 131-133 transforming growth factor beta 1 Homo sapiens 0-8 27177359-8 2017 Overall, these findings suggest that GA C15:1 suppresses lung cancer invasion and migration through the inhibition of PI3K/Akt/mTOR signaling pathway and provide a source of potential therapeutic compounds to control the metastatic dissemination of tumor cells. Gallium 37-39 AKT serine/threonine kinase 1 Homo sapiens 123-126 27177359-8 2017 Overall, these findings suggest that GA C15:1 suppresses lung cancer invasion and migration through the inhibition of PI3K/Akt/mTOR signaling pathway and provide a source of potential therapeutic compounds to control the metastatic dissemination of tumor cells. Gallium 37-39 mechanistic target of rapamycin kinase Homo sapiens 127-131 27922538-1 2017 OBJECTIVE: Our aim was to assess the role of Ga-DOTA-NOC PET/CT as a tool for the management of neuroendocrine tumors (NETs), evaluating the clinical impact on patients from two large NET centers in different geopolitical settings. Gallium 45-47 nocturnin Homo sapiens 53-56 27922538-9 2017 These results support the use of Ga-DOTA-NOC PET/CT contributing significantly toward the clinical management of NET patients. Gallium 33-35 nocturnin Homo sapiens 41-44 28057895-4 2017 The penetrance of this pickle root phenotype in pkl is dramatically increased in gibberellin (GA)-deficient conditions. Gallium 94-96 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 23-29 28057895-4 2017 The penetrance of this pickle root phenotype in pkl is dramatically increased in gibberellin (GA)-deficient conditions. Gallium 94-96 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 48-51 28057895-9 2017 Here, we show that PKL is required for most of GA-promoted developmental processes, including vegetative growth such as hypocotyl, leaf, and inflorescence stem elongation, and phase transitions such as juvenile-to-adult leaf and vegetative-to-reproductive phase. Gallium 47-49 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 19-22 28057895-11 2017 These results indicate that the CHD3 chromatin remodeler PKL is required for regulating gene expression during most of GA-regulated developmental processes. Gallium 119-121 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 32-36 28057895-11 2017 These results indicate that the CHD3 chromatin remodeler PKL is required for regulating gene expression during most of GA-regulated developmental processes. Gallium 119-121 chromatin remodeling factor CHD3 (PICKLE) Arabidopsis thaliana 57-60 28034756-3 2017 In the present study, we are reporting that ectopic expression of AtGIS could regulate glandular trichome development through GA signaling in tobacco. Gallium 126-128 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 66-71 28034756-7 2017 Furthermore, GA treatment could induce expression of AtGIS. Gallium 13-15 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 53-58 27981835-4 2017 To this end, selective and potent MMP-13 inhibitors based on a N,N"-bis(benzyl)pyrimidine-4,6-dicarboxamide core have been synthesized and successfully radiolabeled with carbon-11, fluorine-18, and gallium-68. Gallium 198-205 matrix metallopeptidase 13 Homo sapiens 34-40 28051152-7 2017 We conclude that CBF3 promotes DELLAs accumulation through repressing GA biosynthesis and DELLAs positively regulate CBF3 involving JA signaling. Gallium 70-72 dehydration response element B1A Arabidopsis thaliana 17-21 27672101-2 2017 This study ascertained whether glycyrrhetinic acid (GA; a functional hydrolyzed product of glycyrrhizic acid, which is extracted from herb licorice) can protect against RILI and investigated its relationship to the transforming growth factor (TGF)-beta1/Smads signaling pathway. Gallium 52-54 transforming growth factor, beta 1 Mus musculus 215-253 28382155-12 2017 A blocking study was also performed by co-injection of excess amount of non-radioactive Ga-coupled of CCZ01048, which confirmed that the tumor uptake was MC1R mediated. Gallium 88-90 melanocortin 1 receptor Mus musculus 154-158 27598690-4 2017 However, GA levels in cry1/cry2 mutants in near-null magnetic field were similar to controls. Gallium 9-11 cryptochrome 1 Arabidopsis thaliana 22-26 27598690-4 2017 However, GA levels in cry1/cry2 mutants in near-null magnetic field were similar to controls. Gallium 9-11 cryptochrome 2 Arabidopsis thaliana 27-31 27598690-6 2017 In contrast, expressions of all the detected GA biosynthetic and signaling genes in cry1/cry2 mutants were not affected by near-null magnetic field. Gallium 45-47 cryptochrome 1 Arabidopsis thaliana 84-88 27598690-6 2017 In contrast, expressions of all the detected GA biosynthetic and signaling genes in cry1/cry2 mutants were not affected by near-null magnetic field. Gallium 45-47 cryptochrome 2 Arabidopsis thaliana 89-93 28381798-2 2017 Therefore the present study was designed to evaluate the effects of GA and dodecyl gallate (DGA) against acute and chronic carbon tetrachloride (CCl4)-induced hepatotoxicity. Gallium 68-70 C-C motif chemokine ligand 4 Rattus norvegicus 145-149 27846000-11 2017 Among the five cases evaluated for lesion characterization glioma and atypical meningioma patients showed higher SUVmax in the lesion with Ga PSMA-11 than with F-FDG and converse in cases of lymphoma. Gallium 139-141 folate hydrolase 1 Homo sapiens 142-146 27846000-14 2017 Absence of physiological uptake of Ga PSMA-11 in the normal brain parenchyma results in high TBR values and consequently better visualization of metabolically active disease in brain. Gallium 35-37 folate hydrolase 1 Homo sapiens 38-42 27941377-1 2017 The potential applications of Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT in the imaging of prostate cancer are now well established. Gallium 30-32 folate hydrolase 1 Homo sapiens 77-81 27847212-7 2016 The data provided here indicate that GA is able to inhibit EGFR dependent proliferation and survival signals and induces p38 pathway dependent apoptosis in Malignant Mesothelioma cells. Gallium 37-39 epidermal growth factor receptor Homo sapiens 59-63 27560926-4 2017 We also studied the effect of the HMGB1 inhibitor glycyrrhizin (GA) on high-glucose-induced pSTAT-3 nuclear translocation and upregulation in Muller cells and on pSTAT-3 expression in the retinas of diabetic rats (n = 7-10 in each group). Gallium 64-66 high mobility group box 1 Rattus norvegicus 34-39 27560926-8 2017 GA co-treatment normalized the high-glucose-induced upregulation of HMGB1 and pSTAT-3 upregulation and nuclear translocation in Muller cells. Gallium 0-2 high mobility group box 1 Homo sapiens 68-73 27786380-5 2016 M(Al1-x Gax )4 with M=Sr and Ba and 0.925<=x<=0.975 can be described as a matrix of the binary majority compound in which a low amount of the Ga atoms has been substituted by Al atoms. Gallium 8-10 ephrin A5 Homo sapiens 2-5 27847212-7 2016 The data provided here indicate that GA is able to inhibit EGFR dependent proliferation and survival signals and induces p38 pathway dependent apoptosis in Malignant Mesothelioma cells. Gallium 37-39 mitogen-activated protein kinase 1 Homo sapiens 121-124 27764046-3 2016 The lesion with the highest Ga-PSMA uptake was strongly avid for Ga-DOTATOC, suggesting neuroendocrine tumor differentiation. Gallium 28-30 folate hydrolase 1 Homo sapiens 31-35 27764046-3 2016 The lesion with the highest Ga-PSMA uptake was strongly avid for Ga-DOTATOC, suggesting neuroendocrine tumor differentiation. Gallium 65-67 folate hydrolase 1 Homo sapiens 31-35 27824323-1 2016 A 67-year-old man with prostate adenocarcinoma underwent Ga-labeled prostate-specific membrane antigen (PSMA) ligand PET/CT for restaging due to a rising prostate-specific antigen level. Gallium 57-59 folate hydrolase 1 Homo sapiens 68-102 27824323-1 2016 A 67-year-old man with prostate adenocarcinoma underwent Ga-labeled prostate-specific membrane antigen (PSMA) ligand PET/CT for restaging due to a rising prostate-specific antigen level. Gallium 57-59 folate hydrolase 1 Homo sapiens 104-108 27771904-0 2016 Pilot study: use of gallium-68 PSMA PET for detection of metastatic lesions in patients with renal tumour. Gallium 20-27 folate hydrolase 1 Homo sapiens 31-35 27771904-1 2016 BACKGROUND: In this study, we prospectively evaluate the diagnostic potential of a gallium-68 (68Ga) prostate-specific membrane antigen (PSMA)-binding ligand and positron emission tomography (PET) in detecting metastatic lesions in patients with renal tumour. Gallium 83-90 folate hydrolase 1 Homo sapiens 101-135 27771904-1 2016 BACKGROUND: In this study, we prospectively evaluate the diagnostic potential of a gallium-68 (68Ga) prostate-specific membrane antigen (PSMA)-binding ligand and positron emission tomography (PET) in detecting metastatic lesions in patients with renal tumour. Gallium 83-90 folate hydrolase 1 Homo sapiens 137-141 27541496-0 2016 N availability modulates the role of NPF3.1, a gibberellin transporter, in GA-mediated phenotypes in Arabidopsis. Gallium 75-77 Major facilitator superfamily protein Arabidopsis thaliana 37-43 27835810-7 2016 GA co-treatment attenuated pro-inflammatory cytokines, the thyroid expression of iNOS, TNF-alpha, IL-6 and COX-2, decreased the elevated lipid peroxidation biomarkers and NO level and up- regulated SOD and GST mRNA expression levels. Gallium 0-2 nitric oxide synthase 2 Rattus norvegicus 81-85 27835810-7 2016 GA co-treatment attenuated pro-inflammatory cytokines, the thyroid expression of iNOS, TNF-alpha, IL-6 and COX-2, decreased the elevated lipid peroxidation biomarkers and NO level and up- regulated SOD and GST mRNA expression levels. Gallium 0-2 tumor necrosis factor Rattus norvegicus 87-96 27835810-7 2016 GA co-treatment attenuated pro-inflammatory cytokines, the thyroid expression of iNOS, TNF-alpha, IL-6 and COX-2, decreased the elevated lipid peroxidation biomarkers and NO level and up- regulated SOD and GST mRNA expression levels. Gallium 0-2 interleukin 6 Rattus norvegicus 98-102 27835810-7 2016 GA co-treatment attenuated pro-inflammatory cytokines, the thyroid expression of iNOS, TNF-alpha, IL-6 and COX-2, decreased the elevated lipid peroxidation biomarkers and NO level and up- regulated SOD and GST mRNA expression levels. Gallium 0-2 cytochrome c oxidase II, mitochondrial Rattus norvegicus 107-112 27835810-7 2016 GA co-treatment attenuated pro-inflammatory cytokines, the thyroid expression of iNOS, TNF-alpha, IL-6 and COX-2, decreased the elevated lipid peroxidation biomarkers and NO level and up- regulated SOD and GST mRNA expression levels. Gallium 0-2 hematopoietic prostaglandin D synthase Rattus norvegicus 206-209 27907086-15 2016 Our data suggest that StCDPK3 could be involved in the cross-talk between ABA and GA signaling at the onset of tuber development. Gallium 82-84 calcium-dependent protein kinase 3 Solanum tuberosum 22-29 28774036-1 2016 Regioselective modification of d-glucosamine (2-amino-2-deoxy-d-glucopyranose, GA) through C-1 and C-2 positions to synthesized thermo-responsive D-Glucosamine-poly(N-iso-propylacrylamide) (PNIPAM) via atom transfer radical polymerization (ATRP) was investigated for the first time. Gallium 79-81 heterogeneous nuclear ribonucleoprotein C Homo sapiens 91-102 26795686-16 2016 PATIENT SUMMARY: We examined gallium 68 (68Ga)-prostate-specific membrane antigen (PSMA) HBED-CC positron emission tomography/magnetic resonance imaging (PET/MRI) for primary prostate cancer (PCa) and compared it with multiparametric MRI and PET alone. Gallium 29-36 folate hydrolase 1 Homo sapiens 83-87 27541496-6 2016 We further analyzed its substrate specificity towards different GA species using a yeast heterologous system which revealed that (1) NPF3.1 transported not only bioactive GAs but also their precursors and metabolites and (2) the GAs" import activity of NPF3.1 was not affected by the presence of exogenous nitrate. Gallium 64-66 Major facilitator superfamily protein Arabidopsis thaliana 133-139 27541496-10 2016 Likewise, hypocotyl length measurements showed that the npf3.1 mutants were less sensitive to exogenous GA addition in the presence of paclobutrazol, compared to wild type. Gallium 104-106 Major facilitator superfamily protein Arabidopsis thaliana 56-62 27541496-12 2016 In addition, NPF3.1 gene expression was upregulated by low exogenous nitrate concentrations and the npf3.1 mutants exhibited a not yet described GA-related phenotype under these conditions. Gallium 145-147 Major facilitator superfamily protein Arabidopsis thaliana 13-19 27541496-12 2016 In addition, NPF3.1 gene expression was upregulated by low exogenous nitrate concentrations and the npf3.1 mutants exhibited a not yet described GA-related phenotype under these conditions. Gallium 145-147 Major facilitator superfamily protein Arabidopsis thaliana 100-106 27333090-8 2016 Celiac ganglia showed slight Ga-PSMA-11 uptake in 24 of 40 patients without the presence of any other pathologic lymph nodes in abdominal and pelvic areas. Gallium 29-31 folate hydrolase 1 Homo sapiens 32-36 27634460-9 2016 Although GA-AuNPs and gallic acid suppressed EGF-induced MMP-9 up-regulation via the same signaling pathway, the effective concentration of gallic acid was approximately 100-fold higher than that of GA-AuNPs for inhibition of MMP-9 expression in EGF-treated cells to a similar extent. Gallium 9-11 matrix metallopeptidase 9 Homo sapiens 57-62 27634460-9 2016 Although GA-AuNPs and gallic acid suppressed EGF-induced MMP-9 up-regulation via the same signaling pathway, the effective concentration of gallic acid was approximately 100-fold higher than that of GA-AuNPs for inhibition of MMP-9 expression in EGF-treated cells to a similar extent. Gallium 199-201 matrix metallopeptidase 9 Homo sapiens 226-231 27634460-10 2016 Collectively, our data indicate that, in comparison with gallic acid, GA-AuNPs have a superior ability to inhibit EGF/EGFR-mediated MMP-9 expression in TNBC MDA-MB-231 cells. Gallium 70-72 epidermal growth factor receptor Homo sapiens 118-122 27634460-10 2016 Collectively, our data indicate that, in comparison with gallic acid, GA-AuNPs have a superior ability to inhibit EGF/EGFR-mediated MMP-9 expression in TNBC MDA-MB-231 cells. Gallium 70-72 matrix metallopeptidase 9 Homo sapiens 132-137 27894401-8 2016 Interestingly, SLE patients with AA genotypes of CTLA-4 G-1661A have lower neopterin and MDA concentration compared with GA+GG genotypes. Gallium 121-123 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 49-55 27782132-3 2016 Here, we provide evidence that Arabidopsis SWEET proteins, AtSWEET13 and AtSWEET14, which are members of a family that had previously been linked to sugar transport, are able to mediate cellular GA uptake when expressed in yeast and oocytes. Gallium 195-197 Nodulin MtN3 family protein Arabidopsis thaliana 59-68 27782132-3 2016 Here, we provide evidence that Arabidopsis SWEET proteins, AtSWEET13 and AtSWEET14, which are members of a family that had previously been linked to sugar transport, are able to mediate cellular GA uptake when expressed in yeast and oocytes. Gallium 195-197 Nodulin MtN3 family protein Arabidopsis thaliana 73-82 27782132-4 2016 A double sweet13 sweet14 mutant has a defect in anther dehiscence and this phenotype can be reversed by exogenous GA treatment. Gallium 114-116 Nodulin MtN3 family protein Arabidopsis thaliana 9-16 27782132-4 2016 A double sweet13 sweet14 mutant has a defect in anther dehiscence and this phenotype can be reversed by exogenous GA treatment. Gallium 114-116 Nodulin MtN3 family protein Arabidopsis thaliana 17-24 27658969-4 2016 Combined with the first-principle calculations, the results suggest that the bonding with Fe and Ga or As ions and the ionic distortion near the interface, as well as the FeO defects and oxygen vacancies, may increase the spin-orbit coupling in ultrathin Fe3O4 epitaxial films and in turn provide an enhanced damping. Gallium 97-99 spindlin 1 Homo sapiens 222-226 27501136-1 2016 [(68)Ga]Ga-DOTA-NOC was produced under an Expanded Access IND for 174 clinical PET/CT studies to evaluate patients with neuroendocrine tumors. Gallium 5-7 nocturnin Homo sapiens 16-19 27501136-4 2016 [(68)Ga]Ga-DOTA-NOC radiochemical purity averaged 99.2+-0.4%. Gallium 5-7 nocturnin Homo sapiens 16-19 27531351-8 2016 In 41 patients (95 %) at least one therapeutically-actionable GA was detected, most commonly in EGFR [17 (40 %)]. Gallium 62-64 epidermal growth factor receptor Homo sapiens 96-100 27439715-4 2016 The copackaging of A3G + A3F and A3G + A3H resulted in an additive increase and a modest synergistic increase (1.8-fold) in the frequency of GA-to-AA mutations, respectively. Gallium 141-143 apolipoprotein B mRNA editing enzyme catalytic subunit 3G Homo sapiens 19-22 27439715-4 2016 The copackaging of A3G + A3F and A3G + A3H resulted in an additive increase and a modest synergistic increase (1.8-fold) in the frequency of GA-to-AA mutations, respectively. Gallium 141-143 apolipoprotein B mRNA editing enzyme catalytic subunit 3G Homo sapiens 33-36 27630282-2 2016 The purpose of this study was to evaluate and compare the SSTR2 status by (68)Ga-[tetraxetan-D-Phe1, Tyr3]-octreotide ((68)Ga-DOTATOC) positron-emission tomography (PET) and the tumour metabolic activity by (18)F-fluorodeoxyglucose (FDG) PET in different experimental models of NB. Gallium 78-80 somatostatin receptor 2 Homo sapiens 58-63 27630282-2 2016 The purpose of this study was to evaluate and compare the SSTR2 status by (68)Ga-[tetraxetan-D-Phe1, Tyr3]-octreotide ((68)Ga-DOTATOC) positron-emission tomography (PET) and the tumour metabolic activity by (18)F-fluorodeoxyglucose (FDG) PET in different experimental models of NB. Gallium 123-125 somatostatin receptor 2 Homo sapiens 58-63 26988571-3 2016 With the goal of synthesising charge neutral, low molecular weight, lipophilic gallium complexes with the potential to cross the blood-brain barrier and bind to Abeta plaques we have used an ancillary tetradentate N2O2 Schiff base ligand and the beta-diketone curcumin as a bidentate ligand to give a six-coordinate Ga3+ complex. Gallium 79-86 amyloid beta precursor protein Homo sapiens 161-166 27613195-0 2016 The DAG1 transcription factor negatively regulates the seed-to-seedling transition in Arabidopsis acting on ABA and GA levels. Gallium 116-118 Dof-type zinc finger DNA-binding family protein Arabidopsis thaliana 4-8 27269177-15 2016 CXCL12 serum levels may also be used to distinguish between GA and GH phases of the disease. Gallium 60-62 C-X-C motif chemokine ligand 12 Homo sapiens 0-6 27227784-8 2016 In developing siliques of the cog1-2D mutant the expression of the GA biosynthetic gene GA3OX3 and levels of GA1 are higher than in the wild type. Gallium 67-69 Disease resistance protein (TIR-NBS-LRR class) family Arabidopsis thaliana 30-34 27227784-8 2016 In developing siliques of the cog1-2D mutant the expression of the GA biosynthetic gene GA3OX3 and levels of GA1 are higher than in the wild type. Gallium 67-69 gibberellin 3-oxidase 3 Arabidopsis thaliana 88-94 26790588-0 2016 The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy. Gallium 50-57 folate hydrolase 1 Homo sapiens 71-105 26790588-0 2016 The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy. Gallium 50-57 folate hydrolase 1 Homo sapiens 107-111 26790588-1 2016 The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Gallium 56-63 folate hydrolase 1 Homo sapiens 77-111 26790588-1 2016 The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Gallium 56-63 folate hydrolase 1 Homo sapiens 113-117 27282665-13 2016 CONCLUSIONS: AST and GA synergistically alleviated both BDL-and DMN-induced hepatic fibrosis via TGF-beta1/Smads signaling pathway inhibition in hepatic stellate cells. Gallium 21-23 transforming growth factor, beta 1 Rattus norvegicus 97-106 27248781-6 2016 The PSMA-mediated internalization of (68)Ga-labeled NO3A-DM1-Lys-Urea-Glu displayed a time-dependent manner, allowing the desired drug delivery and release within tumor cells. Gallium 41-43 folate hydrolase 1 Homo sapiens 4-8 27260521-0 2016 Radiation dosimetry of (68)Ga-PSMA-11 (HBED-CC) and preliminary evaluation of optimal imaging timing. Gallium 27-29 folate hydrolase 1 Homo sapiens 30-34 27260521-13 2016 CONCLUSIONS: The mean effective dose of a (68)Ga-PSMA-11 PET is 0.023 mSv/MBq. Gallium 46-48 folate hydrolase 1 Homo sapiens 49-53 26394552-0 2016 Gallium-68 PSMA uptake in adrenal adenoma. Gallium 0-7 folate hydrolase 1 Homo sapiens 11-15 26394552-1 2016 Gallium-68 (Ga-68) labelled prostate-specific membrane antigen (PSMA) imaging by positron emission tomography (PET) has emerged as a promising tool for staging of prostate cancer and restaging of disease in recurrence or biochemical failure after definitive treatment of prostate cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 28-62 26394552-1 2016 Gallium-68 (Ga-68) labelled prostate-specific membrane antigen (PSMA) imaging by positron emission tomography (PET) has emerged as a promising tool for staging of prostate cancer and restaging of disease in recurrence or biochemical failure after definitive treatment of prostate cancer. Gallium 0-7 folate hydrolase 1 Homo sapiens 64-68 26394552-1 2016 Gallium-68 (Ga-68) labelled prostate-specific membrane antigen (PSMA) imaging by positron emission tomography (PET) has emerged as a promising tool for staging of prostate cancer and restaging of disease in recurrence or biochemical failure after definitive treatment of prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 28-62 26394552-1 2016 Gallium-68 (Ga-68) labelled prostate-specific membrane antigen (PSMA) imaging by positron emission tomography (PET) has emerged as a promising tool for staging of prostate cancer and restaging of disease in recurrence or biochemical failure after definitive treatment of prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 64-68 27348517-12 2016 Uptake in B1R+ tumor was higher by using (68)Ga-Z02176 (28.9 +- 6.21 %ID/g) and (18)F-Z04139 (22.6 +- 3.41 %ID/g) than (68)Ga-Z02137 (14.0 +- 4.86 %ID/g). Gallium 45-47 bradykinin receptor, beta 1 Mus musculus 10-13 27348517-13 2016 The B1R+ tumor-to-blood and B1R+ tumor-to-muscle contrast ratios were also higher for (68)Ga-Z02176 (56.1 +- 17.3 and 167 +- 57.6) and (18)F-Z04139 (58.0 +- 20.9 and 173 +- 42.9) than (68)Ga-Z02137 (34.3 +- 15.2 and 103 +- 30.2). Gallium 90-92 bradykinin receptor, beta 1 Mus musculus 4-8 27348517-13 2016 The B1R+ tumor-to-blood and B1R+ tumor-to-muscle contrast ratios were also higher for (68)Ga-Z02176 (56.1 +- 17.3 and 167 +- 57.6) and (18)F-Z04139 (58.0 +- 20.9 and 173 +- 42.9) than (68)Ga-Z02137 (34.3 +- 15.2 and 103 +- 30.2). Gallium 90-92 bradykinin receptor, beta 1 Mus musculus 28-32 27348517-13 2016 The B1R+ tumor-to-blood and B1R+ tumor-to-muscle contrast ratios were also higher for (68)Ga-Z02176 (56.1 +- 17.3 and 167 +- 57.6) and (18)F-Z04139 (58.0 +- 20.9 and 173 +- 42.9) than (68)Ga-Z02137 (34.3 +- 15.2 and 103 +- 30.2). Gallium 188-190 bradykinin receptor, beta 1 Mus musculus 4-8 27255484-5 2016 Overexpression of AtERF11 resulted in elevated bioactive GA levels by up-regulating expression of GA3ox1 and GA20ox genes. Gallium 57-59 eukaryotic release factor 1-1 Arabidopsis thaliana 18-25 27255484-5 2016 Overexpression of AtERF11 resulted in elevated bioactive GA levels by up-regulating expression of GA3ox1 and GA20ox genes. Gallium 57-59 gibberellin 3-oxidase 1 Arabidopsis thaliana 98-104 27255484-7 2016 In addition, yeast two-hybrid, coimmunoprecipitation, and transient expression assays showed that AtERF11 enhances GA signaling by antagonizing the function of DELLA proteins via direct protein-protein interaction. Gallium 115-117 eukaryotic release factor 1-1 Arabidopsis thaliana 98-105 27255484-9 2016 The effect of AtERF11 on promoting GA biosynthesis gene expression is likely via its repressive function on ethylene biosynthesis. Gallium 35-37 eukaryotic release factor 1-1 Arabidopsis thaliana 14-21 27255484-10 2016 These results suggest that AtERF11 plays a dual role in promoting internode elongation by inhibiting ethylene biosynthesis and activating GA biosynthesis and signaling pathways. Gallium 138-140 eukaryotic release factor 1-1 Arabidopsis thaliana 27-34 27322137-0 2016 Synthesis and in Vivo Biological Evaluation of (68)Ga-Labeled Carbonic Anhydrase IX Targeting Small Molecules for Positron Emission Tomography. Gallium 51-53 carbonic anhydrase 9 Mus musculus 62-83 27322137-3 2016 In this study, we present the design and synthesis of novel gallium-radiolabeled small-molecule sulfonamides targeting CA IX. Gallium 60-67 carbonic anhydrase 9 Mus musculus 119-124 27405026-4 2016 We postulate that increased Ga-PSMA uptake within the pagetoid bone relates to neovascularity known to occur in Paget disease. Gallium 28-30 folate hydrolase 1 Homo sapiens 31-35 27248781-8 2016 Small animal PET imaging with (68)Ga-labeled NO3A-DM1-Lys-Urea-Glu exhibited significantly higher uptake (p < 0.01) in the PSMA positive PC3-PIP tumors (4.30 +- 0.20%ID/g) at 1 h postinjection than in the PSMA negative PC3-Flu tumors (1.12 +- 0.42%ID/g). Gallium 34-36 folate hydrolase 1 Homo sapiens 126-130 27248781-8 2016 Small animal PET imaging with (68)Ga-labeled NO3A-DM1-Lys-Urea-Glu exhibited significantly higher uptake (p < 0.01) in the PSMA positive PC3-PIP tumors (4.30 +- 0.20%ID/g) at 1 h postinjection than in the PSMA negative PC3-Flu tumors (1.12 +- 0.42%ID/g). Gallium 34-36 folate hydrolase 1 Homo sapiens 208-212 27160689-10 2016 Moreover, the downregulated expression of Bax in MCF-7/adr cells was restored by GA-13315 markedly. Gallium 81-83 BCL2 associated X, apoptosis regulator Homo sapiens 42-45 27336295-6 2016 The tumor uptake of (68)Ga-labeled peptides in vivo significantly correlated with the in vitro Ki values for NTS1. Gallium 24-26 neurotensin Mus musculus 109-113 27160689-11 2016 CONCLUSION: These data suggest that GA-13315 sensitizes multidrug-resistant cells at least partially by impeding the efflux function of ABCB1. Gallium 36-38 ATP binding cassette subfamily B member 1 Homo sapiens 136-141 27160689-12 2016 The upregulation of Bax by GA-13315 may also contribute to the sensitizing action. Gallium 27-29 BCL2 associated X, apoptosis regulator Homo sapiens 20-23 26975008-1 2016 PURPOSE: Investigating the value of Ga-PSMA-PET/CT in biochemically recurring prostate cancer patients with negative F-choline-PET/CT. Gallium 36-38 folate hydrolase 1 Homo sapiens 39-43 26975008-13 2016 CONCLUSIONS: The sequential imaging approach designed to limit Ga-PSMA imaging to patients with negative choline scans resulted in high detection rates. Gallium 63-65 folate hydrolase 1 Homo sapiens 66-70 27055142-1 2016 Ga-labeled prostate-specific membrane antigen (PSMA) is a potential tool in the imaging of recurrent prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 11-45 27160689-6 2016 RESULTS: GA-13315 selectively killed MCF-7/adr cells that overexpress P-glycoprotein (ABCB1) over the parent MCF-7 cells. Gallium 9-11 ATP binding cassette subfamily B member 1 Homo sapiens 70-84 27160689-6 2016 RESULTS: GA-13315 selectively killed MCF-7/adr cells that overexpress P-glycoprotein (ABCB1) over the parent MCF-7 cells. Gallium 9-11 ATP binding cassette subfamily B member 1 Homo sapiens 86-91 27250997-1 2016 We demonstrate a new patterning technique for gallium-based liquid metals on flat substrates, which can provide both high pattern resolution (~20 mum) and alignment precision as required for highly integrated circuits. Gallium 46-53 latexin Homo sapiens 146-149 27076393-1 2016 (68)Ga-labeled, low-molecular-weight imaging agents that target the prostate-specific membrane antigen (PSMA) are increasingly used clinically to detect prostate and other cancers with positron emission tomography (PET). Gallium 4-6 folate hydrolase 1 Homo sapiens 68-102 27076393-1 2016 (68)Ga-labeled, low-molecular-weight imaging agents that target the prostate-specific membrane antigen (PSMA) are increasingly used clinically to detect prostate and other cancers with positron emission tomography (PET). Gallium 4-6 folate hydrolase 1 Homo sapiens 104-108 27074143-0 2016 Intermetallic Nix My (M = Ga and Sn) Nanocrystals: A Non-precious Metal Catalyst for Semi-Hydrogenation of Alkynes. Gallium 26-28 BCL2 interacting protein 3 like Homo sapiens 14-17 26753602-8 2016 RESULTS: 22/31 patients (71.0 %) were (68)Ga-PSMA-11-positive, while 9/31 (29.0 %) patients were (68)Ga-PSMA-11-negative. Gallium 42-44 folate hydrolase 1 Homo sapiens 45-49 26753602-8 2016 RESULTS: 22/31 patients (71.0 %) were (68)Ga-PSMA-11-positive, while 9/31 (29.0 %) patients were (68)Ga-PSMA-11-negative. Gallium 101-103 folate hydrolase 1 Homo sapiens 104-108 26753602-9 2016 The median PSA value in the (68)Ga-PSMA-11-positive group was significantly higher (median = 2.35 ng/mL; range = 0.19 - 130.0 ng/mL) than in the (68)Ga-PSMA-11-negative group (median value: 0.34 ng/mL; range = 0.10 - 4.20 ng/mL). Gallium 32-34 folate hydrolase 1 Homo sapiens 35-39 26753602-13 2016 Time-activity curves derived from PC-recurrence indicative lesions revealed an increasing (68)Ga-PSMA-11 accumulation during dynamic PET acquisition. Gallium 94-96 folate hydrolase 1 Homo sapiens 97-101 26971788-0 2016 Intra-individual comparison of (68)Ga-PSMA-11-PET/CT and multi-parametric MR for imaging of primary prostate cancer. Gallium 35-37 folate hydrolase 1 Homo sapiens 38-42 26795286-3 2016 (68)Ga-PSMA-(N,N"-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid) ((68)Ga-PSMA) PET/CT was used for patient selection and follow-up after PSMA RLT. Gallium 4-6 folate hydrolase 1 Homo sapiens 7-11 26795286-3 2016 (68)Ga-PSMA-(N,N"-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid) ((68)Ga-PSMA) PET/CT was used for patient selection and follow-up after PSMA RLT. Gallium 4-6 folate hydrolase 1 Homo sapiens 100-104 26795286-3 2016 (68)Ga-PSMA-(N,N"-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid) ((68)Ga-PSMA) PET/CT was used for patient selection and follow-up after PSMA RLT. Gallium 4-6 folate hydrolase 1 Homo sapiens 100-104 27282989-2 2016 It has been demonstrated that DELLAs, which are negative regulators of GA signalling, inhibit phytochrome-interacting factors 3 and 4 (PIF3 and PIF4) by sequestering their DNA-recognition domains. Gallium 71-73 phytochrome interacting factor 3 Arabidopsis thaliana 135-139 27282989-2 2016 It has been demonstrated that DELLAs, which are negative regulators of GA signalling, inhibit phytochrome-interacting factors 3 and 4 (PIF3 and PIF4) by sequestering their DNA-recognition domains. Gallium 71-73 phytochrome interacting factor 4 Arabidopsis thaliana 144-148 27055142-1 2016 Ga-labeled prostate-specific membrane antigen (PSMA) is a potential tool in the imaging of recurrent prostate cancer. Gallium 0-2 folate hydrolase 1 Homo sapiens 47-51 26912439-1 2016 UNLABELLED: (68)Ga-ABY-025 is a radiolabeled Affibody molecule for in vivo diagnosis of human epidermal growth factor receptor 2 (HER2)-positive breast cancer tumors with PET. Gallium 16-18 erb-b2 receptor tyrosine kinase 2 Homo sapiens 94-128 26983703-10 2016 CONCLUSION: The development of a simple and ready-to-use freeze-dried DKFZ-PSMA-11 kit for the preparation of Ga-68-based radiotracers constitutes a major step towards the expedition of the widespread and economical screening of PC patients. Gallium 110-112 folate hydrolase 1 Homo sapiens 75-79 26912439-1 2016 UNLABELLED: (68)Ga-ABY-025 is a radiolabeled Affibody molecule for in vivo diagnosis of human epidermal growth factor receptor 2 (HER2)-positive breast cancer tumors with PET. Gallium 16-18 erb-b2 receptor tyrosine kinase 2 Homo sapiens 130-134 27094616-1 2016 BACKGROUND: Gallium-68 (Ga-68) DOTATATE is a radiolabeled peptide-imaging modality that targets the somatostatin receptor (SSTR), especially subtype 2 (SSTR2). Gallium 12-19 somatostatin receptor 2 Homo sapiens 152-157 26998601-1 2016 Neuronal inclusions of poly(GA), a protein unconventionally translated from G4C2 repeat expansions in C9ORF72, are abundant in patients with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) caused by this mutation. Gallium 28-30 C9orf72-SMCR8 complex subunit Homo sapiens 102-109 27108782-11 2016 Notably, co-treatment of EC109 cells with NaHS and GA (an inhibitor of HSP90 pathway) largely suppressed the aforementioned NaHS-induced effects. Gallium 51-53 heat shock protein 90 alpha family class A member 1 Homo sapiens 71-76 26987028-10 2016 The results showed that both GA and cisplatin changed the morphology, inhibited the growth and induced apoptosis in the H446 cells by inducing generation of ROS, disruption of MMP, downregulation of XIAP expression, and upregulation of Bax, Apaf-1, DIABLO and p53 expression. Gallium 29-31 X-linked inhibitor of apoptosis Homo sapiens 199-203 26993231-0 2016 Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana. Gallium 43-45 GAST1 protein homolog 4 Arabidopsis thaliana 69-74 26993231-0 2016 Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana. Gallium 43-45 Gibberellin-regulated family protein Arabidopsis thaliana 79-84 26993231-3 2016 We have found that GASA4 and GASA6 expression is likely mediated through a repressor of GA responses, GA INSENSITIVE (GAI) protein. Gallium 19-21 Gibberellin-regulated family protein Arabidopsis thaliana 29-34 26993239-0 2016 Dissection of Arabidopsis NCED9 promoter regulatory regions reveals a role for ABA synthesized in embryos in the regulation of GA-dependent seed germination. Gallium 127-129 nine-cis-epoxycarotenoid dioxygenase 9 Arabidopsis thaliana 26-31 26987028-10 2016 The results showed that both GA and cisplatin changed the morphology, inhibited the growth and induced apoptosis in the H446 cells by inducing generation of ROS, disruption of MMP, downregulation of XIAP expression, and upregulation of Bax, Apaf-1, DIABLO and p53 expression. Gallium 29-31 BCL2 associated X, apoptosis regulator Homo sapiens 236-239 26987028-10 2016 The results showed that both GA and cisplatin changed the morphology, inhibited the growth and induced apoptosis in the H446 cells by inducing generation of ROS, disruption of MMP, downregulation of XIAP expression, and upregulation of Bax, Apaf-1, DIABLO and p53 expression. Gallium 29-31 apoptotic peptidase activating factor 1 Homo sapiens 241-247 26987028-10 2016 The results showed that both GA and cisplatin changed the morphology, inhibited the growth and induced apoptosis in the H446 cells by inducing generation of ROS, disruption of MMP, downregulation of XIAP expression, and upregulation of Bax, Apaf-1, DIABLO and p53 expression. Gallium 29-31 diablo IAP-binding mitochondrial protein Homo sapiens 249-255 26987028-10 2016 The results showed that both GA and cisplatin changed the morphology, inhibited the growth and induced apoptosis in the H446 cells by inducing generation of ROS, disruption of MMP, downregulation of XIAP expression, and upregulation of Bax, Apaf-1, DIABLO and p53 expression. Gallium 29-31 tumor protein p53 Homo sapiens 260-263 26987028-12 2016 However, inhibition of the generation of ROS by N-acetyl-l-cysteine (NAC), a specific ROS inhibitor, reversed the cell apoptosis induced by cisplatin combined with GA. Gallium 164-166 X-linked Kx blood group Homo sapiens 69-72 27279903-14 2016 A first-in-man PET/CT study proved the high tumor uptake of this (68)Ga-labeled PSMA-targeting compound. Gallium 69-71 folate hydrolase 1 Homo sapiens 80-84 27021201-7 2016 The cell cycle regulator KRP6 partially represses GA-dependent activation of the cell cycle. Gallium 50-52 KIP-related protein 6 Arabidopsis thaliana 25-29 26998601-5 2016 HR23A and HR23B similarly colocalized to poly(GA) inclusions in C9ORF72 expansion carriers. Gallium 46-48 RAD23 homolog A, nucleotide excision repair protein Mus musculus 0-5 26998601-5 2016 HR23A and HR23B similarly colocalized to poly(GA) inclusions in C9ORF72 expansion carriers. Gallium 46-48 RAD23 homolog B, nucleotide excision repair protein Mus musculus 10-15 26998601-5 2016 HR23A and HR23B similarly colocalized to poly(GA) inclusions in C9ORF72 expansion carriers. Gallium 46-48 C9orf72-SMCR8 complex subunit Homo sapiens 64-71 26887824-2 2016 In flowering genetic pathways, DELLA proteins are master transcriptional regulators of gibberelic acid (GA) pathway, and FLOWERING LOCUS C (FLC) is a core repressor of vernalization pathway as well as downstream of DELLAs. Gallium 104-106 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 121-138 26887824-2 2016 In flowering genetic pathways, DELLA proteins are master transcriptional regulators of gibberelic acid (GA) pathway, and FLOWERING LOCUS C (FLC) is a core repressor of vernalization pathway as well as downstream of DELLAs. Gallium 104-106 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 140-143 27064875-5 2016 Meta-analysis by vasculitis type revealed an association between the GG+GA genotype of the MCP-1 -2518 A/G polymorphism and Behcet"s disease (BD; OR = 1.349, 95% CI = 1.013-1.796, p = 0.040). Gallium 72-74 C-C motif chemokine ligand 2 Homo sapiens 91-96 27014317-3 2016 Most recently, CRY1 N terminus (CNT1) has been found to be involved in CRY1 signaling independent of CCT1, and implicated in the inhibition of gibberellin acids (GA)/brassinosteroids (BR)/auxin-responsive gene expression. Gallium 162-164 cryptochrome 1 Arabidopsis thaliana 15-19 26886512-0 2016 AMD3100: A Versatile Platform for CXCR4 Targeting (68)Ga-Based Radiopharmaceuticals. Gallium 54-56 C-X-C motif chemokine receptor 4 Homo sapiens 34-39 26886512-3 2016 Among the different approaches, which were developed for CXCR4 imaging, a CXCR4 antagonist biscyclam system (AMD3100, also called Mozobil), currently used in the clinic for the mobilization of hematopoietic stem cells, was radiolabeled with different radiometals such as (62)Zn, (64)Cu, (67)Ga, or (99m)Tc. Gallium 291-293 C-X-C motif chemokine receptor 4 Homo sapiens 74-79 26866675-14 2016 Our data suggest that (68)Ga-polyaminocarboxylate chelator-conjugated sulfonamides can be used to noninvasively image CA-IX. Gallium 26-28 carbonic anhydrase 9 Mus musculus 118-123 26116958-1 2016 UNLABELLED: Prostate-specific membrane antigen (PSMA) overexpression theoretically enables targeting of prostate cancer (PCa) metastases using gallium Ga 68 ((68)Ga)-labeled PSMA ligands for positron emission tomography/computed tomography (PET/CT) imaging. Gallium 143-150 folate hydrolase 1 Homo sapiens 12-46 26116958-1 2016 UNLABELLED: Prostate-specific membrane antigen (PSMA) overexpression theoretically enables targeting of prostate cancer (PCa) metastases using gallium Ga 68 ((68)Ga)-labeled PSMA ligands for positron emission tomography/computed tomography (PET/CT) imaging. Gallium 143-150 folate hydrolase 1 Homo sapiens 48-52 26708041-7 2016 Consistently, ABI4 overexpressing seedlings have a lower GA/ABA ratio than the wild type. Gallium 57-59 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 14-18 26708041-9 2016 Taken together, these results suggest that ABA and GA antagonize each other by oppositely acting on ABI4 transcript and protein levels. Gallium 51-53 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 100-104 27069763-10 2016 [(68)Ga]Ga-DOTA-Siglec-9 PET showed significant uptake in lungs, kidneys and urinary bladder. Gallium 5-7 sialic acid binding Ig like lectin 9 Homo sapiens 16-24 27069763-11 2016 Normalization of the net uptake rate (Ki) for the tissue perfusion resulted in 4-fold higher uptake rate of [(68)Ga]Ga-DOTA-Siglec-9 in the ARDS lungs. Gallium 113-115 sialic acid binding Ig like lectin 9 Homo sapiens 124-132 27069766-8 2016 Gene expression of somatostatin receptor subtype (SSTR) 2 and Ki67 were both positively correlated to the (68)Ga-DOTATOC uptake (r=0.89; p<0.0001 and r=0.5; p=0.021, respectively). Gallium 110-112 somatostatin receptor 2 Homo sapiens 19-57 27069766-10 2016 This study as the first verifies a positive and close correlation of (68)Ga-DOTATOC uptake and gene expression of SSTR2 in NEC. Gallium 73-75 somatostatin receptor 2 Homo sapiens 114-119 26818732-6 2016 Similar to SCL3, SEU was repressed by the phytohormone GA and induced by the GA biosynthesis inhibitor paclobutrazol, suggesting that SEU acts downstream of GA signaling to regulate MC formation. Gallium 55-57 SEUSS transcriptional co-regulator Arabidopsis thaliana 17-20 26756315-7 2016 On the other hand, mutant p53 RPMI7951 cell death occurred by PBD-GA-mediated mitochondria- and caspase-dependent pathways via lysosomal membrane permeabilization (LMP), but not through p53 signaling. Gallium 66-68 tumor protein p53 Homo sapiens 26-29 26756315-7 2016 On the other hand, mutant p53 RPMI7951 cell death occurred by PBD-GA-mediated mitochondria- and caspase-dependent pathways via lysosomal membrane permeabilization (LMP), but not through p53 signaling. Gallium 66-68 tumor protein p53 Homo sapiens 186-189 26909116-2 2016 This study investigated the feasibility of non-invasive CXCR4-directed imaging with positron emission tomography/computed tomography (PET/CT) using the radiolabelled chemokine receptor ligand (68)Ga-Pentixafor. Gallium 196-198 C-X-C motif chemokine receptor 4 Homo sapiens 56-61 26909116-11 2016 In this pilot study, (68)Ga-Pentixafor retention has been observed in the vast majority of glioblastoma lesions and served as readout for non-invasive determination of CXCR4 expression. Gallium 25-27 C-X-C motif chemokine receptor 4 Homo sapiens 168-173 26116958-1 2016 UNLABELLED: Prostate-specific membrane antigen (PSMA) overexpression theoretically enables targeting of prostate cancer (PCa) metastases using gallium Ga 68 ((68)Ga)-labeled PSMA ligands for positron emission tomography/computed tomography (PET/CT) imaging. Gallium 143-150 folate hydrolase 1 Homo sapiens 174-178 26711576-2 2016 GA modulated thousands of genes in genome-wide expression studies conducted in THP-1 cells and mouse splenocytes. Gallium 0-2 GLI family zinc finger 2 Homo sapiens 79-84 26517689-1 2016 This study identifies BNIP3L as the key regulator of p53-dependent cell death mechanism in colon cancer cells targeted by the novel gallium based anticancer drug, KP46. Gallium 132-139 BCL2 interacting protein 3 like Homo sapiens 22-28 26517689-1 2016 This study identifies BNIP3L as the key regulator of p53-dependent cell death mechanism in colon cancer cells targeted by the novel gallium based anticancer drug, KP46. Gallium 132-139 tumor protein p53 Homo sapiens 53-56 26463014-4 2016 By adjusting the molar ratios of L-lactide (LA)/glycolide (GA) and (LA+GA)/BPLP, full degradation of BPLP-co-PLGA can be achieved in 8-16 weeks. Gallium 59-61 opiorphin prepropeptide Homo sapiens 101-105 26508290-1 2016 PURPOSE: To evaluate the reproducibility of the combination of hybrid PET/MRI and the (68)Ga-PSMA-11 tracer in depicting lymph node (LN) and bone metastases of prostate cancer (PC) in comparison with that of PET/CT. Gallium 90-92 folate hydrolase 1 Homo sapiens 93-97 26834769-5 2015 The present study has determined that GA co-treated with PEG results in lower HO-1 transcript levels and HO activity, which in turn results in the development of vacuoles in aleurone cells, followed by PCD. Gallium 38-40 heme oxygenase 1 Homo sapiens 78-82 26834769-6 2015 The pharmacology approach illustrated that up- or down-regulated HO-1 gene expression and HO activity delayed or accelerated GA-induced PCD. Gallium 125-127 heme oxygenase 1 Homo sapiens 65-69 26834769-10 2015 Together, these results clearly suggest that HO-1 is involved in the alleviation of GA-induced PCD of drought-triggered rice aleurone layers by associating with NO. Gallium 84-86 heme oxygenase 1 Homo sapiens 45-49 26577262-3 2015 METHODS: PET with the specific CXCR4 ligand, gallium-68 ((68)Ga)-pentixafor, was performed in mice (n = 53) and compared with ex vivo autoradiography, immunohistochemistry, and left ventricular flow cytometry. Gallium 45-52 chemokine (C-X-C motif) receptor 4 Mus musculus 31-36 27108428-0 2016 In Vivo Apoptosis Imaging Using Site-Specifically (68)Ga-Labeled Annexin V. Gallium 54-56 annexin A5 Homo sapiens 65-74 26870182-5 2016 GA induced caspase-3, caspase-9 and reactive oxygen species activity, elevated the expression of apoptosis regulator Bcl-2-like protein 4 and reduced the mitochondrial membrane potential in SMMC-7721 cells. Gallium 0-2 caspase 3 Homo sapiens 11-20 26870182-5 2016 GA induced caspase-3, caspase-9 and reactive oxygen species activity, elevated the expression of apoptosis regulator Bcl-2-like protein 4 and reduced the mitochondrial membrane potential in SMMC-7721 cells. Gallium 0-2 caspase 9 Homo sapiens 22-31 26870182-5 2016 GA induced caspase-3, caspase-9 and reactive oxygen species activity, elevated the expression of apoptosis regulator Bcl-2-like protein 4 and reduced the mitochondrial membrane potential in SMMC-7721 cells. Gallium 0-2 BCL2 associated X, apoptosis regulator Homo sapiens 117-137 27045241-4 2016 In this article, Gallium-68 labeled peptide binding to G protein coupled receptor including SSTR, CCKR1 and GLP1R is addressed, and the application of Gallium-68 labeled somatostin analogues and PET-CT for diagnosis of GEP-NETs is evaluated. Gallium 17-24 glucagon like peptide 1 receptor Homo sapiens 108-113 27045241-5 2016 In conclusion, Gallium-68 labeled peptide and molecular imaging will play important roles in diagnosis, prognosis and therapeutic strategy development of GEP-NETs. Gallium 15-22 granulin precursor Homo sapiens 154-157 26561928-14 2015 The level of TNF-alpha, IL-1beta, and COX-2 was also decreased with GA treatment in NR8383 cells that had been stimulated with lipopolysaccharide (LPS). Gallium 68-70 tumor necrosis factor Rattus norvegicus 13-22 26561928-14 2015 The level of TNF-alpha, IL-1beta, and COX-2 was also decreased with GA treatment in NR8383 cells that had been stimulated with lipopolysaccharide (LPS). Gallium 68-70 interleukin 1 beta Rattus norvegicus 24-32 26561928-14 2015 The level of TNF-alpha, IL-1beta, and COX-2 was also decreased with GA treatment in NR8383 cells that had been stimulated with lipopolysaccharide (LPS). Gallium 68-70 cytochrome c oxidase II, mitochondrial Rattus norvegicus 38-43 26561928-15 2015 Interestingly, GA was found to decrease the level of phosphorylated p65 and IkappaBalpha in NR8383 cells. Gallium 15-17 synaptotagmin 1 Rattus norvegicus 68-71 26561928-15 2015 Interestingly, GA was found to decrease the level of phosphorylated p65 and IkappaBalpha in NR8383 cells. Gallium 15-17 NFKB inhibitor alpha Rattus norvegicus 76-88 26643217-2 2015 To increase the hypoxic tissue uptake, we developed (68)Ga-labeled agents based on mono-, bis-, and trisnitroimidazole conjugates with the chelating agent 1,4,7-triazacyclononane-1,4,7-tris[methyl(2-carboxyethyl)phosphinic acid] (TRAP). Gallium 56-58 acid phosphatase 5, tartrate resistant Mus musculus 230-234 26664145-8 2015 Gallium-68 positron emission tomography/computerizsed tomography-positive patients had a higher, albeit not significantly, OS than those with negative results (75% vs 34.3% at 18 months; P=0.06). Gallium 0-7 Moloney sarcoma oncogene Mus musculus 123-125 26169989-6 2015 RESULTS: Women with the AA alleles of ESR2 RS4986938 had the higher prevalence of lifetime major depression than women with other allele frequencies (36.7 % for those with AA versus 28.5 % with GA and 29.1 % with GG, p = 0.02) and chronic major depression (14.7 % for those with AA versus 9.3 % with GA and 9.1 % with GG, p = 0.01). Gallium 194-196 estrogen receptor 2 Homo sapiens 38-42 26169989-6 2015 RESULTS: Women with the AA alleles of ESR2 RS4986938 had the higher prevalence of lifetime major depression than women with other allele frequencies (36.7 % for those with AA versus 28.5 % with GA and 29.1 % with GG, p = 0.02) and chronic major depression (14.7 % for those with AA versus 9.3 % with GA and 9.1 % with GG, p = 0.01). Gallium 300-302 estrogen receptor 2 Homo sapiens 38-42 26530096-12 2015 CONCLUSION: Ga-DOTA-Siglec-9 PET tracer detected VAP-1 positive vasculature in the mild synovitis of rabbits comparable with 18F-FDG, suggesting its potential for in vivo imaging of synovial inflammation in patients with rheumatic diseases. Gallium 12-14 sialic acid binding Ig like lectin 9 Homo sapiens 20-28 26530096-12 2015 CONCLUSION: Ga-DOTA-Siglec-9 PET tracer detected VAP-1 positive vasculature in the mild synovitis of rabbits comparable with 18F-FDG, suggesting its potential for in vivo imaging of synovial inflammation in patients with rheumatic diseases. Gallium 12-14 amine oxidase copper containing 3 Homo sapiens 49-54 26162799-8 2015 RESULTS: The mean volume of (68)Ga-PSMA-11-positive nodes was 0.5 ml (range 0.2 - 2.3 ml), and the mean short-axis diameter was 5.8 mm (range 2.4 - 13.3 mm). Gallium 32-34 folate hydrolase 1 Homo sapiens 35-39 26252737-2 2015 In this study, we used molecular dynamics to examine the interaction of gallium corroles with Hsp90, and found that they can bind preferentially to the ATP-binding N-terminal site. Gallium 72-79 heat shock protein 90 alpha family class A member 1 Homo sapiens 94-99 26449838-1 2016 UNLABELLED: This work was designed to study the safety, biodistribution, and radiation dosimetry of a gastrin-releasing peptide receptor (GRPR)-targeting, (68)Ga-labeled bombesin (BBN) peptide derivative PET tracer, NOTA-Aca-BBN(7-14) (denoted as (68)Ga-BBN) in healthy volunteers and to assess the level of receptor expression in glioma patients. Gallium 159-161 gastrin releasing peptide receptor Homo sapiens 102-136 26449838-1 2016 UNLABELLED: This work was designed to study the safety, biodistribution, and radiation dosimetry of a gastrin-releasing peptide receptor (GRPR)-targeting, (68)Ga-labeled bombesin (BBN) peptide derivative PET tracer, NOTA-Aca-BBN(7-14) (denoted as (68)Ga-BBN) in healthy volunteers and to assess the level of receptor expression in glioma patients. Gallium 159-161 gastrin releasing peptide receptor Homo sapiens 138-142 26449838-1 2016 UNLABELLED: This work was designed to study the safety, biodistribution, and radiation dosimetry of a gastrin-releasing peptide receptor (GRPR)-targeting, (68)Ga-labeled bombesin (BBN) peptide derivative PET tracer, NOTA-Aca-BBN(7-14) (denoted as (68)Ga-BBN) in healthy volunteers and to assess the level of receptor expression in glioma patients. Gallium 159-161 gastrin releasing peptide Homo sapiens 170-178 26449838-1 2016 UNLABELLED: This work was designed to study the safety, biodistribution, and radiation dosimetry of a gastrin-releasing peptide receptor (GRPR)-targeting, (68)Ga-labeled bombesin (BBN) peptide derivative PET tracer, NOTA-Aca-BBN(7-14) (denoted as (68)Ga-BBN) in healthy volunteers and to assess the level of receptor expression in glioma patients. Gallium 159-161 gastrin releasing peptide Homo sapiens 180-183 26449838-7 2016 RESULTS: (68)Ga-BBN was well tolerated in all healthy volunteers, with no adverse symptoms being noticed or reported. Gallium 13-15 gastrin releasing peptide Homo sapiens 16-19 26294298-1 2015 UNLABELLED: PET imaging with the prostate-specific membrane antigen (PSMA)-targeted radioligand (68)Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer (PCa). Gallium 100-103 folate hydrolase 1 Homo sapiens 69-73 26294298-14 2015 CONCLUSION: Within healthy organs, the kidneys and salivary glands showed the highest (68)Ga-PSMA-617 uptake. Gallium 90-92 folate hydrolase 1 Homo sapiens 93-97 26452854-8 2015 Finally, based on bioactive GA-dependent of the interaction between AtGID1a and DELLA protein, we generated a new method that could identify and detect bioactive GAs accurately and rapidly with surface plasmon resonance assays. Gallium 28-30 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 68-75 26577262-5 2015 RESULTS: In mice, (68)Ga-pentixafor identified regional CXCR4 upregulation in the infarct region, peaking at 3 days (infarct/remote [I/R] ratio 1.5 +- 0.2 at 3 days vs. 1.2 +- 0.3 at 7 days; p = 0.03), corresponding to a flow cytometry-based peak of CD45+ leukocytes and immunohistochemical detection of CD68+ macrophages and Ly6G+ granulocytes. Gallium 22-24 chemokine (C-X-C motif) receptor 4 Mus musculus 56-61 26577262-5 2015 RESULTS: In mice, (68)Ga-pentixafor identified regional CXCR4 upregulation in the infarct region, peaking at 3 days (infarct/remote [I/R] ratio 1.5 +- 0.2 at 3 days vs. 1.2 +- 0.3 at 7 days; p = 0.03), corresponding to a flow cytometry-based peak of CD45+ leukocytes and immunohistochemical detection of CD68+ macrophages and Ly6G+ granulocytes. Gallium 22-24 protein tyrosine phosphatase, receptor type, C Mus musculus 250-254 26577262-5 2015 RESULTS: In mice, (68)Ga-pentixafor identified regional CXCR4 upregulation in the infarct region, peaking at 3 days (infarct/remote [I/R] ratio 1.5 +- 0.2 at 3 days vs. 1.2 +- 0.3 at 7 days; p = 0.03), corresponding to a flow cytometry-based peak of CD45+ leukocytes and immunohistochemical detection of CD68+ macrophages and Ly6G+ granulocytes. Gallium 22-24 CD68 antigen Mus musculus 304-308 26577262-5 2015 RESULTS: In mice, (68)Ga-pentixafor identified regional CXCR4 upregulation in the infarct region, peaking at 3 days (infarct/remote [I/R] ratio 1.5 +- 0.2 at 3 days vs. 1.2 +- 0.3 at 7 days; p = 0.03), corresponding to a flow cytometry-based peak of CD45+ leukocytes and immunohistochemical detection of CD68+ macrophages and Ly6G+ granulocytes. Gallium 22-24 lymphocyte antigen 6 complex, locus G Mus musculus 326-330 26458445-3 2015 For example, GA was able to detect CDKN2A and CDKN2B deletions in a small region only 69kb in size at 9p21 that were frequently found in patients with double-hit lymphoma. Gallium 13-15 cyclin dependent kinase inhibitor 2A Homo sapiens 35-41 26458445-3 2015 For example, GA was able to detect CDKN2A and CDKN2B deletions in a small region only 69kb in size at 9p21 that were frequently found in patients with double-hit lymphoma. Gallium 13-15 cyclin dependent kinase inhibitor 2B Homo sapiens 46-52 26837170-1 2015 To investigate the effects of gambognic acid (GA) on TRAIL-induced apoptosis of cancer cells, human colon HT-29 cancer cells were treated with GA to promote apoptosis. Gallium 46-48 TNF superfamily member 10 Homo sapiens 53-58 26837170-10 2015 GA promoted activation of Caspase-3, -8, and -9 by TRAIL (P<0.05). Gallium 0-2 caspase 3 Homo sapiens 26-47 26837170-10 2015 GA promoted activation of Caspase-3, -8, and -9 by TRAIL (P<0.05). Gallium 0-2 TNF superfamily member 10 Homo sapiens 51-56 26837170-12 2015 In conclusion, GA sensitizes HT-29 cells to TRAIL-induced apoptosis by promoting ROS-activated ERS pathways, up-regulating of DR4 and DR5, and inhibiting c-FLIP expression. Gallium 15-17 TNF superfamily member 10 Homo sapiens 44-49 26837170-12 2015 In conclusion, GA sensitizes HT-29 cells to TRAIL-induced apoptosis by promoting ROS-activated ERS pathways, up-regulating of DR4 and DR5, and inhibiting c-FLIP expression. Gallium 15-17 major histocompatibility complex, class II, DR beta 4 Homo sapiens 126-129 26837170-12 2015 In conclusion, GA sensitizes HT-29 cells to TRAIL-induced apoptosis by promoting ROS-activated ERS pathways, up-regulating of DR4 and DR5, and inhibiting c-FLIP expression. Gallium 15-17 TNF receptor superfamily member 10b Homo sapiens 134-137 26837170-12 2015 In conclusion, GA sensitizes HT-29 cells to TRAIL-induced apoptosis by promoting ROS-activated ERS pathways, up-regulating of DR4 and DR5, and inhibiting c-FLIP expression. Gallium 15-17 CASP8 and FADD like apoptosis regulator Homo sapiens 154-160 26248643-1 2015 RGa {R=HC[C(Me)N(2,6-iPr2C6H3)]2} reacts with Sb(NMe2)3 with insertion into the Sb-N bond and elimination of RGa(NMe2)2 (2), yielding the Ga-substituted distibene R(Me2N)GaSb=SbGa(NMe2 )R (1). Gallium 1-3 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 49-53 26248643-1 2015 RGa {R=HC[C(Me)N(2,6-iPr2C6H3)]2} reacts with Sb(NMe2)3 with insertion into the Sb-N bond and elimination of RGa(NMe2)2 (2), yielding the Ga-substituted distibene R(Me2N)GaSb=SbGa(NMe2 )R (1). Gallium 1-3 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 113-117 26248643-1 2015 RGa {R=HC[C(Me)N(2,6-iPr2C6H3)]2} reacts with Sb(NMe2)3 with insertion into the Sb-N bond and elimination of RGa(NMe2)2 (2), yielding the Ga-substituted distibene R(Me2N)GaSb=SbGa(NMe2 )R (1). Gallium 1-3 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 113-117 26287143-3 2015 The PSMA-targeting ligand Glu-NH-CO-NH-Lys-(Ahx)-HBED-CC (DKFZ-PSMA-11) has superior imaging properties and allows for highly-specific complexation of the generator-based radioisotope Gallium-68 ((68)Ga). Gallium 184-191 folate hydrolase 1 Homo sapiens 4-8 25412869-2 2015 Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Gallium 16-23 folate hydrolase 1 Homo sapiens 89-93 26222320-8 2015 The brain tissue levels of IL-1beta, IL-6, and TNF-alpha were significantly reduced (p < 0.001) in the group treated with GA. Gallium 125-127 interleukin 1 beta Rattus norvegicus 27-35 26222320-8 2015 The brain tissue levels of IL-1beta, IL-6, and TNF-alpha were significantly reduced (p < 0.001) in the group treated with GA. Gallium 125-127 interleukin 6 Rattus norvegicus 37-41 26222320-8 2015 The brain tissue levels of IL-1beta, IL-6, and TNF-alpha were significantly reduced (p < 0.001) in the group treated with GA. Gallium 125-127 tumor necrosis factor Rattus norvegicus 47-56 26206648-0 2015 Results of (68)Gallium-DOTATATE PET/CT Scanning in Patients with Multiple Endocrine Neoplasia Type 1. Gallium 15-22 menin 1 Homo sapiens 65-100 26206648-9 2015 CONCLUSIONS: (68)Gallium-DOTATATE PET/CT is more sensitive for detecting NETs than (111)In-pentetreotide SPECT/CT and CT scan in patients with MEN1. Gallium 17-24 menin 1 Homo sapiens 143-147 26089548-6 2015 RESULTS: PSMA I&T and its cold gallium and lutetium analog revealed nanomolar affinity toward PSMA. Gallium 35-42 folate hydrolase 1 Homo sapiens 98-102 26013479-1 2015 PURPOSE: Gallium-68 (Ga-68)-labeled tracers for imaging expression of the prostate-specific membrane antigen (PSMA) such as the [(68)Ga]Ga-PSMA-HBED-CC have already demonstrated high potential for the detection of recurrent prostate cancer. Gallium 9-16 folate hydrolase 1 Homo sapiens 74-108 26013479-1 2015 PURPOSE: Gallium-68 (Ga-68)-labeled tracers for imaging expression of the prostate-specific membrane antigen (PSMA) such as the [(68)Ga]Ga-PSMA-HBED-CC have already demonstrated high potential for the detection of recurrent prostate cancer. Gallium 9-16 folate hydrolase 1 Homo sapiens 110-114 26013479-1 2015 PURPOSE: Gallium-68 (Ga-68)-labeled tracers for imaging expression of the prostate-specific membrane antigen (PSMA) such as the [(68)Ga]Ga-PSMA-HBED-CC have already demonstrated high potential for the detection of recurrent prostate cancer. Gallium 9-16 folate hydrolase 1 Homo sapiens 139-143 26243314-5 2015 Expression of the key GA biosynthesis gene GA20ox1 in the BR signaling mutant bri1-301 rescues many of its developmental defects. Gallium 22-24 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 43-50 26243314-5 2015 Expression of the key GA biosynthesis gene GA20ox1 in the BR signaling mutant bri1-301 rescues many of its developmental defects. Gallium 22-24 Leucine-rich receptor-like protein kinase family protein Arabidopsis thaliana 78-82 25681404-1 2015 This study aimed at evaluating the potential effect of gallium-incorporated phosphate-based glasses towards periodontitis-associated bacteria, Porphyromonas gingivalis, and matrix metalloproteinase-13. Gallium 55-62 matrix metallopeptidase 13 Homo sapiens 173-200 25681404-5 2015 In vitro study investigated the effect of gallium on purified recombinant human matrix metalloproteinase-13 activity using matrix metalloproteinase assay kit. Gallium 42-49 matrix metallopeptidase 13 Homo sapiens 80-107 25999035-0 2015 A shortcut to high-affinity Ga-68 and Cu-64 radiopharmaceuticals: one-pot click chemistry trimerisation on the TRAP platform. Gallium 28-30 TRAP Homo sapiens 111-115 25997858-0 2015 Synthesis of (68)Ga-labeled NOTA-RGD-GE11 heterodimeric peptide for dual integrin and epidermal growth factor receptor-targeted tumor imaging. Gallium 17-19 epidermal growth factor receptor Homo sapiens 86-118 25957851-1 2015 With the advent of (68)Ga-labeled prostate-specific membrane antigen-N,N"-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid ((68)Ga-PSMA-HBED-CC) positron emission tomography (PET) hybrid imaging in prostate cancer (PCa), even small metastatic lymph nodes (LNs) can be visualized. Gallium 23-25 folate hydrolase 1 Homo sapiens 154-158 26112024-3 2015 (68)Ga-PSMA (Glu-NH-CO-NH-Lys-(Ahx)-[(68)Ga-N,N"-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid]) has shown promising results in retrospective trials. Gallium 4-6 folate hydrolase 1 Homo sapiens 7-11 26287143-3 2015 The PSMA-targeting ligand Glu-NH-CO-NH-Lys-(Ahx)-HBED-CC (DKFZ-PSMA-11) has superior imaging properties and allows for highly-specific complexation of the generator-based radioisotope Gallium-68 ((68)Ga). Gallium 184-191 folate hydrolase 1 Homo sapiens 63-67 26753456-5 2015 Carriers of the IL-10-1082A>G variant were found to be associated with the Gleason score (GS) > 7 (AA versus GA+GG, OR = 3.47, 95% CI 1.11-10.88, p = 0.033). Gallium 115-117 interleukin 10 Homo sapiens 16-21 25575510-2 2015 It has been previously reported that unconventional repeat-associated non-ATG (RAN) translation of GGGGCC GGCCCC repeats produces five types of dipeptide-repeat proteins (referred to as RAN proteins): poly-glycine-alanine (GA), poly-glycine-proline (GP), poly-glycine-arginine (GR), poly-proline-arginine (PR) and poly-proline-alanine (PA). Gallium 223-225 RAN, member RAS oncogene family Homo sapiens 79-82 25575510-2 2015 It has been previously reported that unconventional repeat-associated non-ATG (RAN) translation of GGGGCC GGCCCC repeats produces five types of dipeptide-repeat proteins (referred to as RAN proteins): poly-glycine-alanine (GA), poly-glycine-proline (GP), poly-glycine-arginine (GR), poly-proline-arginine (PR) and poly-proline-alanine (PA). Gallium 223-225 RAN, member RAS oncogene family Homo sapiens 186-189 25684649-15 2015 CONCLUSIONS: Chelators had a clear influence on the biodistribution and targeting properties of (68)Ga-labeled antagonistic BN analogs. Gallium 100-102 gastrin releasing peptide Homo sapiens 124-126 25760032-2 2015 This reactivity can be extended by using two equivalents of the respective Lewis acid EBr3 (E=Al, Ga) to form the 2:1 Lewis acid-base adducts trans-[(Cy3 P)2 (Br3 Al-Br)Pt(B OAlBr3 )] (18) and trans-[(Cy3 P)2 (Br3 Ga-Br)Pt(B OGaBr3 )] (15). Gallium 98-100 EBR3 Homo sapiens 86-90 26083951-0 2015 Integrin alphavbeta3 as a Promising Target to Image Neoangiogenesis Using In-House Generator-Produced Positron Emitter (68)Ga-Labeled DOTA-Arginine-Glycine-Aspartic Acid (RGD) Ligand. Gallium 123-125 integrin subunit alpha V Homo sapiens 0-20 25790062-6 2015 The MTS reaction using a constitutional isomer of for-HBH that transposed the methylene unit to the carboxylic acid containing region, 5-[(5-aminopentyl)(hydroxy)amino]-5-oxopentanoic acid (for-PPH), gave the macrocycle for-[Fe(HPDFOE)] in a yield significantly less than that for for-[Fe(HHDFOE)], with the gallium(III) analogue for-[Ga(HPDFOE)] unable to be detected. Gallium 308-315 hemoglobin subunit alpha 1 Homo sapiens 54-57 25790062-6 2015 The MTS reaction using a constitutional isomer of for-HBH that transposed the methylene unit to the carboxylic acid containing region, 5-[(5-aminopentyl)(hydroxy)amino]-5-oxopentanoic acid (for-PPH), gave the macrocycle for-[Fe(HPDFOE)] in a yield significantly less than that for for-[Fe(HHDFOE)], with the gallium(III) analogue for-[Ga(HPDFOE)] unable to be detected. Gallium 335-337 hemoglobin subunit alpha 1 Homo sapiens 54-57 25656233-4 2015 We show that GA-related targets are enriched among genes responsive to BBX24 under shade and that the shade-response defect in bbx24 mutants is rescued by a GA treatment that promotes DELLA degradation. Gallium 13-15 B-box zinc finger family protein Arabidopsis thaliana 71-76 25745086-14 2015 Uptake values of (68)Ga-labeled P03034, P04158, and Z02090 in B1R+ tumors were 2.17 +- 0.49, 19.6 +- 4.50, and 14.4 +- 1.63 percentage injected dose per gram, respectively. Gallium 21-23 bradykinin receptor, beta 1 Mus musculus 62-65 25745086-17 2015 With significantly higher tumor uptake and target-to-nontarget ratios, (68)Ga-labeled P04158 and Z02090 are superior to P03034 for imaging B1R expression with PET. Gallium 75-77 bradykinin receptor, beta 1 Mus musculus 139-142 25745086-17 2015 With significantly higher tumor uptake and target-to-nontarget ratios, (68)Ga-labeled P04158 and Z02090 are superior to P03034 for imaging B1R expression with PET. Gallium 75-77 thyroid stimulating hormone receptor Mus musculus 159-162 25825591-7 2015 RESULTS: We found a significant association between TNF-alpha-238 guanine to alanine (GA) polymorphism and carriers of variant allele A between NAFLD patients with and without CAD (P < 0.05). Gallium 86-88 tumor necrosis factor Homo sapiens 52-61 25689638-4 2015 We found evidence of the association between CTLA-4 A49G polymorphism and colorectal cancer risk (GG vs. AA: OR = 2.01, 95% CI = 1.29-3.07, P = 0.002; GA vs. AA: OR = 2.32, 95% CI = 1.53-3.57, P = 0.001; GA + GG vs. AA: OR = 2.16, 95% CI = 1.46-3.21, P = 0.001). Gallium 151-153 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 45-51 25816210-10 2015 The TNF-alpha antagonist (SPD-304) and the RIP1 inhibitor (necrostatin-1, Nec-1) confirmed GA-induced TNFR1-mediated necroptosis. Gallium 91-93 tumor necrosis factor Homo sapiens 4-13 25816210-10 2015 The TNF-alpha antagonist (SPD-304) and the RIP1 inhibitor (necrostatin-1, Nec-1) confirmed GA-induced TNFR1-mediated necroptosis. Gallium 91-93 receptor interacting serine/threonine kinase 1 Homo sapiens 43-47 25816210-10 2015 The TNF-alpha antagonist (SPD-304) and the RIP1 inhibitor (necrostatin-1, Nec-1) confirmed GA-induced TNFR1-mediated necroptosis. Gallium 91-93 proprotein convertase subtilisin/kexin type 1 Homo sapiens 74-79 25816210-10 2015 The TNF-alpha antagonist (SPD-304) and the RIP1 inhibitor (necrostatin-1, Nec-1) confirmed GA-induced TNFR1-mediated necroptosis. Gallium 91-93 TNF receptor superfamily member 1A Homo sapiens 102-107 25592229-4 2015 The aim of the study was to synthesize and investigate the APN/CD13 specificity of a novel (68)Ga-labeled NOTA-c(NGR) molecule in vivo using miniPET. Gallium 95-97 alanyl aminopeptidase, membrane Rattus norvegicus 59-62 25592229-4 2015 The aim of the study was to synthesize and investigate the APN/CD13 specificity of a novel (68)Ga-labeled NOTA-c(NGR) molecule in vivo using miniPET. Gallium 95-97 reticulon 4 receptor Rattus norvegicus 113-116 25592229-12 2015 Using orthotopic transplantation, metastases were developed which showed specific (68)Ga-NOTA-c(NGR) uptake. Gallium 86-88 reticulon 4 receptor Rattus norvegicus 96-99 25680796-5 2015 Knockdown of JMJ524 by RNAi caused a GA-insensitive dwarf phenotype with shrunken leaves and shortened internodes. Gallium 37-39 JmjC-domain protein JMJ524 Solanum lycopersicum 13-19 25680796-8 2015 Nevertheless, only the overexpression of SlGLD1 in tomato resulted in a GA-insensitive dwarf phenotype, suggesting that SlGLD1 acts as a repressor of GA signalling. Gallium 72-74 DELLA protein GAI Solanum lycopersicum 41-47 25635133-13 2015 CONCLUSION: (68)Ga-DOTATATE uptake correlates with SSTR2 expression and offers high diagnostic accuracy to delineate meningioma from tumor-free tissue even in recurrent tumors after previous therapy. Gallium 16-18 somatostatin receptor 2 Homo sapiens 51-56 25676129-7 2015 These results demonstrate that RPN1a may be involved in trichome development through the GA and CK signaling pathways. Gallium 89-91 26S proteasome regulatory subunit S2 1A Arabidopsis thaliana 31-36 25618648-8 2015 Sensitivity in KPC-2 producing category was moderate( 66.7%) using a GA-LDA model. Gallium 69-71 carbapenem-hydrolyzing beta-lactamase KPC-2 Klebsiella pneumoniae 15-20 25656233-4 2015 We show that GA-related targets are enriched among genes responsive to BBX24 under shade and that the shade-response defect in bbx24 mutants is rescued by a GA treatment that promotes DELLA degradation. Gallium 13-15 B-box zinc finger family protein Arabidopsis thaliana 127-132 25049073-0 2015 Gallium-68-labeled anti-HER2 single-chain Fv fragment: development and in vivo monitoring of HER2 expression. Gallium 0-7 erb-b2 receptor tyrosine kinase 2 Homo sapiens 24-28 25049073-0 2015 Gallium-68-labeled anti-HER2 single-chain Fv fragment: development and in vivo monitoring of HER2 expression. Gallium 0-7 erb-b2 receptor tyrosine kinase 2 Homo sapiens 93-97 25049073-1 2015 PURPOSE: We aimed to develop a gallium-68 (Ga-68)-labeled single-chain variable fragment (scFv) targeting the human epidermal growth factor receptor 2 (HER2) to rapidly and noninvasively evaluate the status of HER2 expression. Gallium 31-38 immunglobulin heavy chain variable region Homo sapiens 90-94 25049073-1 2015 PURPOSE: We aimed to develop a gallium-68 (Ga-68)-labeled single-chain variable fragment (scFv) targeting the human epidermal growth factor receptor 2 (HER2) to rapidly and noninvasively evaluate the status of HER2 expression. Gallium 31-38 erb-b2 receptor tyrosine kinase 2 Homo sapiens 110-150 25049073-1 2015 PURPOSE: We aimed to develop a gallium-68 (Ga-68)-labeled single-chain variable fragment (scFv) targeting the human epidermal growth factor receptor 2 (HER2) to rapidly and noninvasively evaluate the status of HER2 expression. Gallium 31-38 erb-b2 receptor tyrosine kinase 2 Homo sapiens 152-156 25049073-1 2015 PURPOSE: We aimed to develop a gallium-68 (Ga-68)-labeled single-chain variable fragment (scFv) targeting the human epidermal growth factor receptor 2 (HER2) to rapidly and noninvasively evaluate the status of HER2 expression. Gallium 31-38 erb-b2 receptor tyrosine kinase 2 Homo sapiens 210-214 26064388-4 2015 As regarding rs62625044 in HTR3E gene, we found there was a significant different between the case and the control group in the distribution of GA genotype and A allele in female but not in male. Gallium 144-146 5-hydroxytryptamine receptor 3E Homo sapiens 27-32 25053229-2 2015 We examined whether gallium-68 (Ga-68)-labeled anti-CD163-antibody can detect the receptor in vivo. Gallium 20-27 CD163 molecule Rattus norvegicus 52-57 25053229-2 2015 We examined whether gallium-68 (Ga-68)-labeled anti-CD163-antibody can detect the receptor in vivo. Gallium 32-34 CD163 molecule Rattus norvegicus 52-57 25475723-9 2015 These results suggest that AtCSP2 negatively regulates seed germination by controlling ABA and GA levels. Gallium 95-97 glycine rich protein 2 Arabidopsis thaliana 27-33 26514519-7 2015 In the subgroup analysis by ethnicity, we detected significant associations between the CYP1A2 rs762551 polymorphism and bladder cancer susceptibility for GA vs GG (OR = 0.78, 95% CI =0.64~0.96) and for the recessive model (OR=0.80, 95% CI=0.66~0.96) in Caucasians, but not for Asians. Gallium 155-157 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 88-94 25640346-11 2015 It was interesting that high-concentration (150 muM) GNPs-GA was not toxic to normal cells, whereas GA alone was cytotoxic. Gallium 58-60 latexin Homo sapiens 48-51 25356824-3 2015 Here we report that GA plays its role through the activation of AMP-activated protein kinase (AMPK) and by regulating mitochondrial function via the activation of peroxisome proliferator-activated receptor-gamma coactivator1alpha (PGC1alpha). Gallium 20-22 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 163-229 25356824-3 2015 Here we report that GA plays its role through the activation of AMP-activated protein kinase (AMPK) and by regulating mitochondrial function via the activation of peroxisome proliferator-activated receptor-gamma coactivator1alpha (PGC1alpha). Gallium 20-22 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 231-240 25356824-9 2015 Taken together, these results indicate that GA plays its beneficial metabolic roles by activating the AMPK/Sirt1/PGC1alpha pathway and by changing the interscapular brown adipose tissue genes related to thermogenesis. Gallium 44-46 sirtuin 1 Mus musculus 107-112 25356824-9 2015 Taken together, these results indicate that GA plays its beneficial metabolic roles by activating the AMPK/Sirt1/PGC1alpha pathway and by changing the interscapular brown adipose tissue genes related to thermogenesis. Gallium 44-46 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 113-122 25205572-5 2014 The TSN1 OE lines displayed phenotypes that may be attributed to the overproduction of GA. Gallium 87-89 TUDOR-SN protein 1 Arabidopsis thaliana 4-8 25240913-1 2015 INTRODUCTION: The purpose of this study was the development of (68)Ga-labeled neolactosylated human serum albumin (LSA) for imaging asialoglycoprotein receptors in the liver by using positron emission tomography (PET), which would enable functional imaging with higher resolution than single-photon emission computed tomography (SPECT). Gallium 67-69 albumin Mus musculus 100-113 25560300-7 2015 BDNF Val66Met interacted with both IL-1beta rs13032029 (Val/Met+ TT, PPerm = 0.029), and IL-6 rs2069837 (Val/Val+ AA, PPerm = 0.021) in Europeans, in addition to IL-1beta rs16944 (Val/Val+ GA, PPerm = 0.006) in African Americans. Gallium 189-191 brain derived neurotrophic factor Homo sapiens 0-4 25294298-4 2014 The singlet Ga4 and Ga8 clusters can be constructed in a singlet ground state from the Ga-dimers in the first excited triplet state of the Ga2-molecule, the (3)Sigmag(-) state. Gallium 12-14 electron transfer flavoprotein subunit alpha Homo sapiens 139-142 24972112-0 2014 Gallium-68-labeled affibody molecule for PET imaging of PDGFRbeta expression in vivo. Gallium 0-7 platelet derived growth factor receptor beta Homo sapiens 56-65 24972112-14 2014 In conclusion, the (68)Ga-labeled affibody molecule Z09591 is a promising candidate for further development as a probe for imaging PDGFRbeta expression in vivo using PET. Gallium 23-25 platelet derived growth factor receptor beta Homo sapiens 131-140 25049057-1 2015 In the present study, interactions of Au(III) and Ga(III) ions on human serum albumin (HSA) were studied comparatively via spectroscopic and thermal analysis methods: UV-vis absorbance spectroscopy, fluorescence spectroscopy, Fourier transform infrared (FT-IR) spectroscopy and isothermal titration calorimetry (ITC). Gallium 50-53 albumin Homo sapiens 87-90 25049057-3 2015 It was found that both Au(III) and Ga(III) ions can interact with HSA, however; Au(III) ions interact with HSA more favorably and with a higher affinity. Gallium 35-37 albumin Homo sapiens 66-69 25049057-3 2015 It was found that both Au(III) and Ga(III) ions can interact with HSA, however; Au(III) ions interact with HSA more favorably and with a higher affinity. Gallium 35-37 albumin Homo sapiens 107-110 25049057-4 2015 FT-IR second derivative analysis results demonstrated that, high concentrations of both metal ions led to a considerable decrease in the alpha-helix content of HSA; while Au(III) led to around 5% of decrease in the alpha-helix content at 200muM, it was around 1% for Ga(III) at the same concentration. Gallium 267-269 albumin Homo sapiens 160-163 25049057-5 2015 Calorimetric analysis gave the binding kinetics of metal-HSA interactions; while the binding affinity (Ka) of Au(III)-HSA binding was around 3.87x10(5)M(-1), it was around 9.68x10(3)M(-1) for Ga(III)-HSA binding. Gallium 192-194 albumin Homo sapiens 57-60 25049057-5 2015 Calorimetric analysis gave the binding kinetics of metal-HSA interactions; while the binding affinity (Ka) of Au(III)-HSA binding was around 3.87x10(5)M(-1), it was around 9.68x10(3)M(-1) for Ga(III)-HSA binding. Gallium 192-194 albumin Homo sapiens 118-121 25049057-5 2015 Calorimetric analysis gave the binding kinetics of metal-HSA interactions; while the binding affinity (Ka) of Au(III)-HSA binding was around 3.87x10(5)M(-1), it was around 9.68x10(3)M(-1) for Ga(III)-HSA binding. Gallium 192-194 albumin Homo sapiens 118-121 27142500-1 2015 (68)Gallium (Ga)-PSMA PET/CT (PSMA stands for "prostate-specific membrane antigen") is a new diagnostic tool for patients with prostate cancer or with prostate cancer metastases. Gallium 4-11 folate hydrolase 1 Homo sapiens 17-21 27142500-1 2015 (68)Gallium (Ga)-PSMA PET/CT (PSMA stands for "prostate-specific membrane antigen") is a new diagnostic tool for patients with prostate cancer or with prostate cancer metastases. Gallium 4-11 folate hydrolase 1 Homo sapiens 30-34 27142500-7 2015 Furthermore, the (68)Ga-PSMA can be produced in the investigating hospital with a gallium generator. Gallium 82-89 folate hydrolase 1 Homo sapiens 24-28 27142505-1 2015 (68)Gallium (Ga)-PSMA PET/CT scans have been introduced in clinical practice in the Netherlands too. Gallium 4-11 folate hydrolase 1 Homo sapiens 17-21 26078814-6 2015 NaHS treatment in gibberellic acid- (GA-) treated aleurone layers also delayed the PCD process, reduced the content of O2 (-), and increased POD activity while decreasing LOX activity. Gallium 37-39 prx7 Hordeum vulgare 142-145 25738547-6 2015 Here we show that the GA biosynthesis inhibitor paclobutrazol substantially reduces the long hypocotyl and petiole phenotypes of Arabidopsis elf3 mutants. Gallium 22-24 hydroxyproline-rich glycoprotein family protein Arabidopsis thaliana 141-145 26055937-0 2014 Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy. Gallium 43-45 strawberry notch homolog 1 Homo sapiens 20-23 26116124-4 2014 The affinity of the (nat)gallium and lutetium complexes to PSMA and the internalization efficiency of the radiotracers were determined on PSMA-expressing LNCaP cells. Gallium 25-32 folate hydrolase 1 Homo sapiens 59-63 25040905-8 2014 The ERF-associated amphiphilic repression (EAR) motif-containing region of XopDXcc8004 interacts with the DELLA domain of RGA and might interfere with the GA-induced binding of GID1, a GA receptor, to RGA. Gallium 123-125 GRAS family transcription factor family protein Arabidopsis thaliana 201-204 25227717-6 2014 While improvement of the brain uptake of (68)Ga complexes appears to be essential, these results suggest that novel PET imaging probes that include (68)Ga as the radionuclide for PET may be feasible. Gallium 152-154 thyroid stimulating hormone receptor Mus musculus 116-119 25227717-6 2014 While improvement of the brain uptake of (68)Ga complexes appears to be essential, these results suggest that novel PET imaging probes that include (68)Ga as the radionuclide for PET may be feasible. Gallium 152-154 thyroid stimulating hormone receptor Mus musculus 179-182 25131538-0 2014 Screening and identification of novel compounds with potential anti-proliferative effects on gallium-resistant lung cancer through an AXL kinase pathway. Gallium 93-100 AXL receptor tyrosine kinase Homo sapiens 134-137 25093246-2 2014 We aimed to evaluate (68)gallium-BNOTA-PRGD2 ((68)Ga-PRGD2) as a new reagent for noninvasive integrin alphavbeta3 imaging in glioma patients. Gallium 25-32 integrin subunit alpha V Homo sapiens 93-113 25117641-3 2014 Despite preclinical efficacy of geldanamycin-anasamycin (GA)-derivatives containing benzoquinone moiety as Hsp90 inhibitors, the hepatotoxicity of these GA-derivatives restricts their therapeutic benefit. Gallium 57-59 heat shock protein 90 alpha family class A member 1 Homo sapiens 107-112 25056926-7 2014 These phenotypes were probably attributed to de-phosphomimic RGA, which retained its transcriptional activation activity that induces GA biosynthetic genes, but lost the transcription repressor function that inhibits GA-responsive genes. Gallium 134-136 GRAS family transcription factor family protein Arabidopsis thaliana 61-64 25056926-9 2014 In contrast, phosphomimic RGA overexpression caused GA-deficient phenotypes with non-degradable RGA. Gallium 27-29 GRAS family transcription factor family protein Arabidopsis thaliana 96-99 25046113-0 2014 GA binding protein augments autophagy via transcriptional activation of BECN1-PIK3C3 complex genes. Gallium 0-2 beclin 1 Homo sapiens 72-77 25046113-0 2014 GA binding protein augments autophagy via transcriptional activation of BECN1-PIK3C3 complex genes. Gallium 0-2 phosphatidylinositol 3-kinase catalytic subunit type 3 Homo sapiens 78-84 25075574-3 2014 GA reversed glutamate-suppressed B-cell lymphoma 2 levels, inhibited glutamate-enhanced expressions of Bax and cleaved caspase 3, and reduced cytochrome C (Cyto C) release. Gallium 0-2 BCL2 associated X, apoptosis regulator Rattus norvegicus 103-106 25075574-4 2014 Exposure to glutamate strongly inhibited phosphorylation of AKT (protein kinase B) and extracellular signal-regulated kinases (ERKs); however, GA pretreatment enhanced activation of ERKs but not AKT. Gallium 143-145 AKT serine/threonine kinase 1 Rattus norvegicus 60-63 24903095-0 2014 Targeting P-selectin by gallium-68-labeled fucoidan positron emission tomography for noninvasive characterization of vulnerable plaques: correlation with in vivo 17.6T MRI. Gallium 24-31 selectin, platelet Mus musculus 10-20 24444547-7 2014 On the other hand, GA co-treatment exhibited a significant protection by reverting back the altered levels of LDH-isoenzymes, antioxidants, collagen and MMP-2/MMP-9 activities. Gallium 19-21 matrix metallopeptidase 2 Mus musculus 153-158 24845461-5 2014 Through studies in human MS and its animal model, experimental autoimmune encephalomyelitis (EAE), we have discovered two novel CD8+ T cell populations that play an essential immunoregulatory role in disease: (1) MHC class Ia-restricted neuroantigen-specific "autoregulatory" CD8+ T cells and (2) glatiramer acetate (GA/Copaxone( )) therapy-induced Qa-1/HLA-E-restricted GA-specific CD8+ T cells. Gallium 317-319 CD8a molecule Homo sapiens 128-131 25010794-7 2014 Genetic and biochemical analyses indicated that TOPP4 regulates GA signal transduction mainly via promoting DELLA protein degradation. Gallium 64-66 type one serine/threonine protein phosphatase 4 Arabidopsis thaliana 48-53 24989044-4 2014 In this study, we demonstrate that LIP1 is specifically expressed in the epidermis and that its L1 box sequence mediates GA-induced transcription. Gallium 121-123 Ras-related small GTP-binding family protein Arabidopsis thaliana 35-39 25035403-6 2014 GA responsiveness was decreased in the double mutant gaf1 idd1, whereas it was enhanced in a GAF1 overexpressor. Gallium 0-2 Polymerase/histidinol phosphatase-like protein Arabidopsis thaliana 53-62 24979809-5 2014 GA is known to promote flowering, and we find that svp mutants contain elevated levels of GA that correlate with GA-related phenotypes such as early flowering and organ elongation. Gallium 0-2 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 51-54 24979809-6 2014 The ga20ox2 mutation suppresses the elevated GA levels and partially suppresses the growth and early flowering phenotypes of svp mutants. Gallium 45-47 gibberellin 20 oxidase 2 Arabidopsis thaliana 4-11 24444547-7 2014 On the other hand, GA co-treatment exhibited a significant protection by reverting back the altered levels of LDH-isoenzymes, antioxidants, collagen and MMP-2/MMP-9 activities. Gallium 19-21 matrix metallopeptidase 9 Mus musculus 159-164 24444547-8 2014 The results of this study indicate that topical application of GA inhibits DMBA/Croton oil induced two-stage skin carcinogenic process by modulating the antioxidants and MMPs (-2 & -9) in the mouse skin. Gallium 63-65 matrix metallopeptidase 2 Mus musculus 170-174 25010794-11 2014 These studies provide direct evidence for a crucial role of protein dephosphorylation mediated by TOPP4 in the GA signaling pathway. Gallium 111-113 type one serine/threonine protein phosphatase 4 Arabidopsis thaliana 98-103 24633452-0 2014 A new (68)Ga-labeled BBN peptide with a hydrophilic linker for GRPR-targeted tumor imaging. Gallium 10-12 gastrin releasing peptide Homo sapiens 21-24 24633452-0 2014 A new (68)Ga-labeled BBN peptide with a hydrophilic linker for GRPR-targeted tumor imaging. Gallium 10-12 gastrin releasing peptide receptor Homo sapiens 63-67 24633452-13 2014 The accumulation of (68)Ga-labeled GRPR antagonists in the subcutaneous PC-3 tumors could be visualized via small animal PET. Gallium 24-26 gastrin releasing peptide receptor Homo sapiens 35-39 24816840-6 2014 In addition, exogenous application of bioactive GA could promote GhSusA1 expression in cultured fibers, as well as in cotton hypocotyls. Gallium 48-50 sucrose synthase 2 Gossypium hirsutum 65-72 24530366-0 2014 Biodistribution of a (67)Ga-labeled anti-TNF VHH single-domain antibody containing a bacterial albumin-binding domain (Zag). Gallium 25-27 tumor necrosis factor Mus musculus 41-44 24530366-0 2014 Biodistribution of a (67)Ga-labeled anti-TNF VHH single-domain antibody containing a bacterial albumin-binding domain (Zag). Gallium 25-27 alpha-2-glycoprotein 1, zinc Mus musculus 119-122 24651198-2 2014 Here we report the first thermally robust monomeric MX2 radicals of gallium, indium and thallium. Gallium 68-75 MX dynamin like GTPase 2 Homo sapiens 52-55 24761071-1 2014 (68)Ga-labelled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-NaI3-Octreotide ((68)Ga-DOTANOC) positron emission tomography/computed tomography (PET/CT) is an excellent modality in patients with carcinoma of unknown primary of neuroendocrine origin. Gallium 4-6 mediator complex subunit 25 Homo sapiens 75-82 24598702-4 2014 Our results demonstrated that there was a borderline evidence of an association between the Aurora-A V57I polymorphism and the decreased risk of overall cancer in two genetic models: AA vs. GA+GG and AA vs. GG. Gallium 190-192 aurora kinase A Homo sapiens 92-100 24528333-3 2014 The long-distance effect of GA4 was demonstrated by the observation that its application to the shoot apex of the GA-deficient mutant ga3ox1/ga3ox2 rescued the short-root phenotype. Gallium 28-30 gibberellin 3-oxidase 1 Arabidopsis thaliana 134-140 24528333-3 2014 The long-distance effect of GA4 was demonstrated by the observation that its application to the shoot apex of the GA-deficient mutant ga3ox1/ga3ox2 rescued the short-root phenotype. Gallium 28-30 gibberellin 3-oxidase 2 Arabidopsis thaliana 141-147 24528333-8 2014 Reciprocal grafting of GA-deficient mutant plants to 35S::CLE6 transformants complemented the shoot phenotype associated with GA deficiency, demonstrating the systemic effect of CLE6 from root to shoot. Gallium 23-25 CLAVATA3/ESR-RELATED 6 Arabidopsis thaliana 178-182 24528333-8 2014 Reciprocal grafting of GA-deficient mutant plants to 35S::CLE6 transformants complemented the shoot phenotype associated with GA deficiency, demonstrating the systemic effect of CLE6 from root to shoot. Gallium 126-128 CLAVATA3/ESR-RELATED 6 Arabidopsis thaliana 58-62 24685237-7 2014 CONCLUSION: Taken together, the cumulative effects of SNPs of ORAI1 gene in breast cancer association study were well demonstrated in terms of GA-generated SNP models. Gallium 143-145 ORAI calcium release-activated calcium modulator 1 Homo sapiens 62-67 24491461-1 2014 We have developed a novel radiogallium (Ga)-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging. Gallium 40-42 C-X-C motif chemokine receptor 4 Homo sapiens 112-117 24520274-6 2014 The meta-analysis showed a significant correlation between the UGRP1-112G/A polymorphism and asthma for AA versus GG (P=0.01) and AA versus GA/GG (P=0.02). Gallium 140-142 secretoglobin family 3A member 2 Homo sapiens 63-68 24438818-6 2014 Biodistribution of (68)Ga-DOTA-NGR was determined in normal mice by dissection method. Gallium 23-25 reticulon 4 receptor Mus musculus 31-34 24438818-7 2014 (68)Ga-DOTA-NGR PET was performed in A549 and MDA-MB231 xenografts, and included dynamic and static imaging. Gallium 4-6 reticulon 4 receptor Mus musculus 12-15 24438818-9 2014 RESULTS: The radiochemical purity of (68)Ga-DOTA-NGR was 98.0% +- 1.4% with a specific activity of about 17.49 MBq/nmol. Gallium 41-43 reticulon 4 receptor Homo sapiens 49-52 24380838-9 2014 Furthermore, 18beta-GA, DAG, 20(S)-GF1 and Rh1 at 10 muM significantly inhibited CYP3A4/5 activity, while emodin activated the metabolism of midazolam in human liver microsomes. Gallium 19-22 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 81-87 24438818-16 2014 CONCLUSIONS: (68)Ga-DOTA-NGR was easily synthesized and showed favorable biodistribution and kinetics. Gallium 17-19 reticulon 4 receptor Homo sapiens 25-28 24438818-17 2014 (68)Ga-DOTA-NGR could also specifically bind to the APN receptor in vitro and in vivo, and might be a potential molecular probe for the noninvasive detection of APN-positive tumors and neovasculature. Gallium 4-6 reticulon 4 receptor Homo sapiens 12-15 24438818-17 2014 (68)Ga-DOTA-NGR could also specifically bind to the APN receptor in vitro and in vivo, and might be a potential molecular probe for the noninvasive detection of APN-positive tumors and neovasculature. Gallium 4-6 alanyl aminopeptidase, membrane Homo sapiens 52-55 24438818-17 2014 (68)Ga-DOTA-NGR could also specifically bind to the APN receptor in vitro and in vivo, and might be a potential molecular probe for the noninvasive detection of APN-positive tumors and neovasculature. Gallium 4-6 alanyl aminopeptidase, membrane Homo sapiens 161-164 24574031-1 2014 The reaction of fac-[M(III)F3(Me3tacn)] x H2O with Gd(NO3)3 5H2O affords a series of fluoride-bridged, trigonal bipyramidal {Gd(III)3M(III)2} (M = Cr (1), Fe (2), Ga (3)) complexes without signs of concomitant GdF3 formation, thereby demonstrating the applicability even of labile fluoride-complexes as precursors for 3d-4f systems. Gallium 163-165 FA complementation group C Homo sapiens 16-19 24331419-0 2014 Hydrogen sulfide delays GA-triggered programmed cell death in wheat aleurone layers by the modulation of glutathione homeostasis and heme oxygenase-1 expression. Gallium 24-26 heme oxygenase 1, chloroplastic Triticum aestivum 133-149 24294902-4 2014 Stimulation of DCs with GA and GB resulted in up-regulation of CD40, CD86 and MHC-II molecules indicating their effects on the maturation of DCs. Gallium 24-26 CD40 antigen Mus musculus 63-67 24294902-4 2014 Stimulation of DCs with GA and GB resulted in up-regulation of CD40, CD86 and MHC-II molecules indicating their effects on the maturation of DCs. Gallium 24-26 CD86 antigen Mus musculus 69-73 24294902-4 2014 Stimulation of DCs with GA and GB resulted in up-regulation of CD40, CD86 and MHC-II molecules indicating their effects on the maturation of DCs. Gallium 24-26 histocompatibility-2, MHC Mus musculus 78-84 24294902-7 2014 In conclusion, these results indicate that GA and GB may insert their immunomodulatory effects by enhancing DC maturation and modulating Th1/Th2 response through an increase in Th1 responses, implying their beneficial in host defense against infectious diseases. Gallium 43-45 negative elongation factor complex member C/D, Th1l Mus musculus 137-140 24294902-7 2014 In conclusion, these results indicate that GA and GB may insert their immunomodulatory effects by enhancing DC maturation and modulating Th1/Th2 response through an increase in Th1 responses, implying their beneficial in host defense against infectious diseases. Gallium 43-45 negative elongation factor complex member C/D, Th1l Mus musculus 177-180 23994402-13 2014 CONCLUSIONS: SOCS1 prevents GA progression by preserving endothelial function and attenuating cytokine-induced adhesion molecule expression in vascular endothelium. Gallium 28-30 suppressor of cytokine signaling 1 Mus musculus 13-18 24404203-4 2014 Exogenous GA application increased the expression level of AtEXP2 during seed germination, while ABA application had no effect on AtEXP2 expression. Gallium 10-12 expansin A2 Arabidopsis thaliana 59-65 24331419-10 2014 NaHS-triggered HO-1 gene expression in GA-treated layers was also confirmed. Gallium 39-41 heme oxygenase 1, chloroplastic Triticum aestivum 15-19 24418890-6 2013 GA also inhibited, under stress conditions, phosphorylation of eIF2alpha and stress granule formation. Gallium 0-2 eukaryotic translation initiation factor 2A Homo sapiens 63-72 24497809-2 2014 We here present (68)Ga-labelled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-Nal3-Octreotide positron emission tomography computed tomography findings in a 52 year old female with VHL syndrome, demonstrating both CNS and visceral tumors. Gallium 20-22 mediator complex subunit 25 Homo sapiens 91-98 24281950-3 2014 Furthermore, the levels of the bioactive phytohormone GA4 as well as of several intermediates of the GA biosynthetic pathway are reduced in AtGRP7-ox plants. Gallium 54-56 cold, circadian rhythm, and rna binding 2 Arabidopsis thaliana 140-146 24281950-8 2014 Thus, exogenous GA has only a small additional effect in reducing the number of leaves at the onset of flowering in AtGRP7-ox plants. Gallium 16-18 cold, circadian rhythm, and rna binding 2 Arabidopsis thaliana 116-122 24415299-12 2014 Boy with GG Cdx2 genotype had lower total Ca (GG = 2.3 +- 0.17 mmol/l, GA+AA = 2.43 +- 0.17 mmol/l, p = 0.004) compare with carriers of A allele. Gallium 71-73 caudal type homeobox 2 Homo sapiens 12-16 25060207-0 2014 Positron emission tomographic imaging of copper 64- and gallium 68-labeled chelator conjugates of the somatostatin agonist tyr3-octreotate. Gallium 56-63 somatostatin Homo sapiens 102-114 24192296-5 2014 The induction of those genes triggered by shoot-applied GA4 was observed, even in the fit-2 mutant which had reduced endogenous GA levels caused by treatment with paclobutrazol (PBZ), a GA biosynthesis inhibitor. Gallium 128-130 gibberellin 3-oxidase 1 Arabidopsis thaliana 56-59 24009336-5 2013 We found that the recombinant CYP714A1 protein catalyzes the conversion of GA12 to 16-carboxylated GA12 (16-carboxy-16beta,17-dihydro GA12), a previously unidentified GA metabolite. Gallium 75-77 cytochrome P450, family 714, subfamily A, polypeptide 1 Arabidopsis thaliana 30-38 24374505-7 2014 These results suggested that overexpression of GhMADS14 in Arabidopsis may alter expression levels of the genes related to GA biosynthetic and metabolic pathways, resulting in the reduction of endogenous GA amounts in cells. Gallium 123-125 agamous-like MADS-box protein AGL11 Gossypium hirsutum 47-55 24374505-7 2014 These results suggested that overexpression of GhMADS14 in Arabidopsis may alter expression levels of the genes related to GA biosynthetic and metabolic pathways, resulting in the reduction of endogenous GA amounts in cells. Gallium 204-206 agamous-like MADS-box protein AGL11 Gossypium hirsutum 47-55 24163006-6 2014 On the other hand, agelasine (AGL) and garcinolic acid (GA) facilitated the P2X7 response to ATP in all three cell populations. Gallium 56-58 purinergic receptor P2X 7 Homo sapiens 76-80 24163006-7 2014 GA also enhanced the YO-PRO-1 uptake, whereas AGL did not affect the ATP-stimulated intracellular accumulation of this dye. Gallium 0-2 lamin A/C Homo sapiens 24-29 24376736-9 2013 The pooled results suggested the CTLA-4 60G/A polymorphism was significantly associated with an increased skin cancer risk (AA vs. GG: OR = 1.32, 95%CI = 1.09-1.59; AA vs. GA+GG: OR = 1.26, 95%CI = 1.07-1.48). Gallium 172-174 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 33-39 23910093-0 2013 GA-optimized feedforward-PID tracking control for a rugged electrohydraulic system design. Gallium 0-2 metastasis associated 1 family member 2 Homo sapiens 25-28 23958249-4 2013 (68)Ga-DOTATATE is a (68)Ga-labeled radiotracer with specific affinity to somatostatin receptor subtype-2 (SSTR-2). Gallium 4-6 somatostatin receptor 2 Mus musculus 74-105 23982476-3 2013 The 6-COOH group of GA, especially its beta configuration, was found to be an indispensable pharmacophore group for GA recognition and binding to AtGID1A. Gallium 20-22 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 146-153 23979969-10 2013 These studies further our fundamental understanding of the regulation of GA biosynthesis and catabolism at the tissue and organ level and demonstrate that the timing/localization of GA3ox expression within an organ affects both GA homeostasis and GA1 levels, and thereby growth. Gallium 73-75 succinyl-CoA:glutarate-CoA transferase Homo sapiens 182-185 24116792-0 2013 Spontaneous growth of gallium-filled microcapillaries on ion-bombarded GaN. Gallium 22-29 gigaxonin Homo sapiens 71-74 23958249-4 2013 (68)Ga-DOTATATE is a (68)Ga-labeled radiotracer with specific affinity to somatostatin receptor subtype-2 (SSTR-2). Gallium 4-6 somatostatin receptor 2 Mus musculus 107-113 23818868-11 2013 Accordingly, further genetic analysis showed that abi4 recovered the delayed germination phenotype of cyp707a1 and cyp707a2 and further, rescued the non-germinating phenotype of ga1-t. Taken together, this study suggests that ABI4 is a key factor that regulates primary seed dormancy by mediating the balance between ABA and GA biogenesis. Gallium 325-327 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 50-54 23878229-6 2013 In line with a critical regulatory role for GNC and GNL downstream from both auxin and GA signaling, we show here that the constitutive activation of GA signaling is sufficient to suppress arf2 mutant phenotypes through repression of GNC and GNL. Gallium 87-89 auxin response factor 2 Arabidopsis thaliana 189-193 23818171-2 2013 GA binding to the GIBBERELLIN-INSENSITIVE DWARF1 (GID1) GA receptors stimulates GID1-GA-DELLA complex formation, which in turn triggers DELLA protein ubiquitination and proteolysis via the SCF(SLY1) E3 ubiquitin ligase and 26S proteasome. Gallium 0-2 F-box family protein Arabidopsis thaliana 193-197 23624123-7 2013 The presence of variant A-allele for CD3EAP rs967591 was associated with increased lung cancer risk [GA versus GG, OR (95% CI)=2.53 (1.16-5.48), P=0.02 and GA+AA versus GG, OR (95% CI)=2.46 (1.16-5.20), P=0.02]. Gallium 101-103 RNA polymerase I subunit G Homo sapiens 37-43 23683509-5 2013 The final step in GA biosynthesis is catalysed by StGA3ox1 and StGA3ox2 activity, that convert inactive forms of GA into active GA1 and GA4. Gallium 18-20 gibberellin 3-beta-dioxygenase 1-like Solanum tuberosum 63-71 23612252-7 2013 Overall, significant association was found between the CCR2-V64I polymorphism and cancer risk (OR=1.84, 95% CI=1.35-2.51, AA vs GA/GG, P=0.37). Gallium 128-130 C-C motif chemokine receptor 2 Homo sapiens 55-59 23579096-7 2013 Activation of IGF-1R, after GA addition, promoted a reduction in the catalase content through the constitutive activation of Ras and erk1/2 proteins which were, in turn, responsible of the observed GA-induced senescence. Gallium 28-30 insulin like growth factor 1 receptor Homo sapiens 14-20 23579096-7 2013 Activation of IGF-1R, after GA addition, promoted a reduction in the catalase content through the constitutive activation of Ras and erk1/2 proteins which were, in turn, responsible of the observed GA-induced senescence. Gallium 198-200 insulin like growth factor 1 receptor Homo sapiens 14-20 23579096-7 2013 Activation of IGF-1R, after GA addition, promoted a reduction in the catalase content through the constitutive activation of Ras and erk1/2 proteins which were, in turn, responsible of the observed GA-induced senescence. Gallium 198-200 catalase Homo sapiens 69-77 23579096-7 2013 Activation of IGF-1R, after GA addition, promoted a reduction in the catalase content through the constitutive activation of Ras and erk1/2 proteins which were, in turn, responsible of the observed GA-induced senescence. Gallium 198-200 mitogen-activated protein kinase 3 Homo sapiens 133-139 23698293-5 2013 On the other hand, APOBEC3F and to a lesser extent other APOBEC3 members induce G-to-A changes within the nucleotide GA. Gallium 117-119 apolipoprotein B mRNA editing enzyme catalytic subunit 3F Homo sapiens 19-27 23764439-1 2013 The application of an inductively coupled plasma mass spectrometry (ICP-MS) assay for quantifying in vitro binding of a gallium-based anticancer drug, tris(8-quinolinolato)gallium(III), to serum albumin and transferrin and in human serum is described. Gallium 120-127 transferrin Homo sapiens 207-218 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 75-109 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 118-152 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 154-158 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 187-191 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 207-213 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor B Homo sapiens 215-221 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor C Homo sapiens 223-229 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor D Homo sapiens 231-237 23741766-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-vascular endothelial growth factor-121 The vascular endothelial growth factor (VEGF) family is composed of five VEGF glycoproteins (VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E) and includes at least six isoforms of various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 platelet derived growth factor C Homo sapiens 243-249 23741766-13 2004 (11) prepared (68)Ga-1,4,7-triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-VEGF121 ((68)Ga-NOTA-VEGF121) for use with positron emission tomography (PET) imaging of VEGFR expression in nude mice bearing U87MG human glioblastoma xenografts. Gallium 18-20 kinase insert domain receptor Homo sapiens 178-183 23235484-6 2013 The objective of this pictorial article was to provide an illustrative tutorial showing the clinical utility of Ga-labeled somatostatin analog [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-NaI3-octreotide (Ga-DOTANOC) PET/CT for imaging usual and unusual metastatic sites in patients with NETs. Gallium 112-114 mediator complex subunit 25 Homo sapiens 202-209 23679914-2 2013 We found that the activation barrier of H2O dissociation at the kinked site of the Ga-terminated GaN surface is about 0.8 eV, which is significantly lower than that at the stepped site of about 1.2 eV. Gallium 83-85 gigaxonin Homo sapiens 97-100 23700641-0 2004 (111)In/(68)Ga-Labeled anti-epidermal growth factor receptor, native chemical ligation cyclized Affibody ZHER2:342min The human epidermal growth factor receptor-2 (HER2, ErbB2) modulates its activity through a tyrosine kinase (TK) signaling pathway and is involved in the development of a variety of cancers (1, 2). Gallium 12-14 epidermal growth factor receptor Homo sapiens 28-60 23679914-3 2013 This is consistent with the experimental observation where a step-terrace structure is observed after the etching process of Ga-terminated GaN surfaces with catalyst-referred etching method. Gallium 125-127 gigaxonin Homo sapiens 139-142 23299948-6 2013 In patients with ectopic ACTH secretion, Ga-68-DOTANOC-PET/CT may play an important role in the localization of EAPA. Gallium 41-43 proopiomelanocortin Homo sapiens 25-29 23142764-5 2013 Another notable function of MYC2 is the regulation of crosstalk between the signaling pathways of JA and those of other phytohormones such as abscisic acid (ABA), salicylic acid (SA), gibberellins (GAs), and auxin (IAA). Gallium 198-201 Basic helix-loop-helix (bHLH) DNA-binding family protein Arabidopsis thaliana 28-32 23425858-3 2013 We recently characterized the function of a core component of the GA signal transduction pathway: RGL3. Gallium 66-68 ral guanine nucleotide dissociation stimulator like 3 Homo sapiens 98-102 23179945-0 2013 PET imaging with a [68Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions. Gallium 25-32 folate hydrolase 1 Homo sapiens 42-46 23390663-0 2004 (68)Ga-Labeled DOTA-conjugated sCCK8[Phe(2)(p-CH2SO3H),Nle(3,6)], a sulfated cholecystokinin 8 (sCCK8) peptide derivative The three subtypes of the cholecystokinin (CCK) receptor (CCKR), designated CCK1R, CCK2R, and CCK2i4svR, belong to the G-protein-coupled receptor family and are classified on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 4-6 cholecystokinin B receptor Homo sapiens 205-210 23695543-6 2013 Even with these additional production mechanisms, open ocean GA concentrations would have remained at or below ~1 muM, much smaller than the 1-2 M concentrations required for prebiotic synthesis routes like those proposed by Powner et al. Gallium 61-63 latexin Homo sapiens 114-117 23390663-0 2004 (68)Ga-Labeled DOTA-conjugated sCCK8[Phe(2)(p-CH2SO3H),Nle(3,6)], a sulfated cholecystokinin 8 (sCCK8) peptide derivative The three subtypes of the cholecystokinin (CCK) receptor (CCKR), designated CCK1R, CCK2R, and CCK2i4svR, belong to the G-protein-coupled receptor family and are classified on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 4-6 cholecystokinin Homo sapiens 32-35 23390663-0 2004 (68)Ga-Labeled DOTA-conjugated sCCK8[Phe(2)(p-CH2SO3H),Nle(3,6)], a sulfated cholecystokinin 8 (sCCK8) peptide derivative The three subtypes of the cholecystokinin (CCK) receptor (CCKR), designated CCK1R, CCK2R, and CCK2i4svR, belong to the G-protein-coupled receptor family and are classified on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 4-6 cholecystokinin A receptor Homo sapiens 198-203 23469825-10 2013 The highest luminescence intensity is found for Gd3(Ga,Al)5O12 with 40% of Al(3+) replaced by Ga(3+). Gallium 52-54 GRDX Homo sapiens 48-51 23463984-0 2013 Gallium analogue of soluble Prussian blue KGa[Fe(CN)6] nH2O: synthesis, characterization, and potential biomedical applications. Gallium 0-7 glutaminase Homo sapiens 42-45 23463984-1 2013 The gallium analogue of the soluble Prussian blue with the formula KGa[Fe(CN)6] nH2O is synthesized and structurally characterized. Gallium 4-11 glutaminase Homo sapiens 67-70 23086343-7 2013 We also demonstrate that GA-induced reserve mobilization, SlCysEP accumulation and processing, and PCD in tomato endosperm are antagonized by ABA. Gallium 25-27 KDEL-tailed cysteine endopeptidase CysEP Solanum lycopersicum 58-65 23390663-0 2004 (68)Ga-Labeled DOTA-conjugated sCCK8[Phe(2)(p-CH2SO3H),Nle(3,6)], a sulfated cholecystokinin 8 (sCCK8) peptide derivative The three subtypes of the cholecystokinin (CCK) receptor (CCKR), designated CCK1R, CCK2R, and CCK2i4svR, belong to the G-protein-coupled receptor family and are classified on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 4-6 cholecystokinin Homo sapiens 97-100 23390663-0 2004 (68)Ga-Labeled DOTA-conjugated sCCK8[Phe(2)(p-CH2SO3H),Nle(3,6)], a sulfated cholecystokinin 8 (sCCK8) peptide derivative The three subtypes of the cholecystokinin (CCK) receptor (CCKR), designated CCK1R, CCK2R, and CCK2i4svR, belong to the G-protein-coupled receptor family and are classified on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 4-6 gastrin Homo sapiens 347-354 23459406-0 2013 Novel molecular imaging of atherosclerosis with gallium-68-labeled apolipoprotein A-I mimetic peptide and positron emission tomography. Gallium 48-55 apolipoprotein A-I Oryctolagus cuniculus 67-85 23304755-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-Cpa-cyclo(d-Cys-amino-Phe-hydroorotic acid-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)-D-Tyr-NH2 (JR11) Somatostatin (SST) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 growth hormone 1 Homo sapiens 215-227 23304755-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-Cpa-cyclo(d-Cys-amino-Phe-hydroorotic acid-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)-D-Tyr-NH2 (JR11) Somatostatin (SST) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 insulin Homo sapiens 239-246 23304757-0 2004 (68)Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-Cpa-cyclo(d-Cys-amino-Phe-hydroorotic acid-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)-D-Tyr-NH2 (JR11) Somatostatin (SST) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 growth hormone 1 Homo sapiens 214-226 23304757-0 2004 (68)Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-Cpa-cyclo(d-Cys-amino-Phe-hydroorotic acid-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)-D-Tyr-NH2 (JR11) Somatostatin (SST) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 insulin Homo sapiens 238-245 22879045-2 2013 In order to study these effects in vivo a new (68)Ga-labeled PET tracer was developed which serves as a substrate of the Pgp and therefore indirectly mirrors the Pgp activity. Gallium 50-52 ATP binding cassette subfamily B member 1 Homo sapiens 121-124 22879045-2 2013 In order to study these effects in vivo a new (68)Ga-labeled PET tracer was developed which serves as a substrate of the Pgp and therefore indirectly mirrors the Pgp activity. Gallium 50-52 ATP binding cassette subfamily B member 1 Homo sapiens 162-165 23096079-2 2013 In the present study, we prepared and evaluated (68)Ga-1,4,7-triazacyclononane-1,4,7-triacetic acid-benzyl (NOTA)-VEGF(121) as a positron emission tomography (PET) radioligand for the in vivo imaging of VEGFR expression. Gallium 52-54 vascular endothelial growth factor A Homo sapiens 114-118 23096079-2 2013 In the present study, we prepared and evaluated (68)Ga-1,4,7-triazacyclononane-1,4,7-triacetic acid-benzyl (NOTA)-VEGF(121) as a positron emission tomography (PET) radioligand for the in vivo imaging of VEGFR expression. Gallium 52-54 kinase insert domain receptor Homo sapiens 203-208 24858991-8 2013 The results for VKORC1 were as follows: 49.5% (GG), 28.6% (GA), and 22.0% (AA); meanwhile, those for the genotype CYP4F2 were 57.1% (CC), 34.1% (CT), and 7.7% (TT). Gallium 59-61 vitamin K epoxide reductase complex subunit 1 Homo sapiens 16-22 23090695-11 2013 Together, our results suggested that HO-1 is involved in NO- and cGMP-induced alpha-Amy2/54 gene expression in GA-treated aleurone layers. Gallium 111-113 heme oxygenase 1, chloroplastic Triticum aestivum 37-41 23536800-6 2013 Many GA-responsive gene expression alterations in the brm-1 mutant are likely due to depleted levels of active GAs. Gallium 5-7 transcription regulatory protein SNF2 Arabidopsis thaliana 54-57 23536800-8 2013 Given the central position occupied by SWI/SNF complexes within regulatory networks controlling fundamental biological processes, the identification of diverse functional intersections of BRM with GA-dependent processes in this study suggests a role for SWI/SNF in facilitating crosstalk between GA-mediated regulation and other cellular pathways. Gallium 197-199 transcription regulatory protein SNF2 Arabidopsis thaliana 188-191 23536800-8 2013 Given the central position occupied by SWI/SNF complexes within regulatory networks controlling fundamental biological processes, the identification of diverse functional intersections of BRM with GA-dependent processes in this study suggests a role for SWI/SNF in facilitating crosstalk between GA-mediated regulation and other cellular pathways. Gallium 296-298 transcription regulatory protein SNF2 Arabidopsis thaliana 188-191 23383017-9 2013 A shared GA-rich motif was identified in three of these genes but had opposite effects on expression when mutated in the nmr-1 and twk-16 DVA regulatory elements. Gallium 9-11 LITAF domain-containing protein Caenorhabditis elegans 121-126 23437128-7 2013 Several sugar-responsive and GA biosynthetic gene expressions were altered in the cbl1 mutant. Gallium 29-31 calcineurin B-like protein 1 Arabidopsis thaliana 82-86 23383017-9 2013 A shared GA-rich motif was identified in three of these genes but had opposite effects on expression when mutated in the nmr-1 and twk-16 DVA regulatory elements. Gallium 9-11 TWiK family of potassium channels Caenorhabditis elegans 131-137 22918762-0 2013 (68)Ga-labeled bombesin analogs for receptor-mediated imaging. Gallium 4-6 gastrin releasing peptide Homo sapiens 15-23 23256568-4 2012 This study aims to demonstrate that inhibition of the heat shock protein 90 (Hsp90) either by inhibitors geldanamycin/17-N-Allylamino-17-demethoxygeldanamycin (GA/17-AAG) or siRNA technique in human lung cancer cells induces c-FLIPL degradation and cellular apoptosis through C-terminus of Hsp70-interacting protein (CHIP)-mediated mechanisms. Gallium 160-162 heat shock protein 90 alpha family class A member 1 Homo sapiens 54-75 23256568-4 2012 This study aims to demonstrate that inhibition of the heat shock protein 90 (Hsp90) either by inhibitors geldanamycin/17-N-Allylamino-17-demethoxygeldanamycin (GA/17-AAG) or siRNA technique in human lung cancer cells induces c-FLIPL degradation and cellular apoptosis through C-terminus of Hsp70-interacting protein (CHIP)-mediated mechanisms. Gallium 160-162 heat shock protein 90 alpha family class A member 1 Homo sapiens 77-82 23256568-4 2012 This study aims to demonstrate that inhibition of the heat shock protein 90 (Hsp90) either by inhibitors geldanamycin/17-N-Allylamino-17-demethoxygeldanamycin (GA/17-AAG) or siRNA technique in human lung cancer cells induces c-FLIPL degradation and cellular apoptosis through C-terminus of Hsp70-interacting protein (CHIP)-mediated mechanisms. Gallium 160-162 CASP8 and FADD like apoptosis regulator Homo sapiens 225-232 23256220-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-HER2-specific Affibody ZHER2:2891 Epidermal growth factor (EGF) is a 53-amino acid growth factor (6.2 kDa) that is secreted by ectodermic cells, monocytes, kidneys, and duodenal glands (1). Gallium 4-6 erb-b2 receptor tyrosine kinase 2 Homo sapiens 69-73 23166959-7 2004 It was demonstrated that (64)Cu- or (68)Ga-labeled AE105 can be used with PET to detect and visualize xenograft tumors that overexpressed uPAR in rodents (5, 6). Gallium 40-42 plasminogen activator, urokinase receptor Homo sapiens 138-142 23136680-0 2004 (68)Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2 Somatostatin (SST) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 insulin Homo sapiens 212-219 23136682-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2 Somatostatin (SSTR) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 growth hormone 1 Homo sapiens 190-202 23136682-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2 Somatostatin (SSTR) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 insulin Homo sapiens 214-221 23136682-15 2004 (10) prepared (68)Ga-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-LM3 ((68)Ga-DOTA-LM3) as a positron emission tomography (PET) imaging agent for SSTR2. Gallium 18-20 somatostatin receptor 2 Homo sapiens 158-163 23115809-0 2004 (11)C/(68)Ga-Labeled sel-tagged anti-epidermal growth factor receptor 2 affibody ZHER2:342 The human epidermal growth factor receptor-2 (HER2, ErbB2) modulates its activity through a tyrosine kinase signaling pathway and is involved in the development of various types of cancers (1, 2). Gallium 10-12 erb-b2 receptor tyrosine kinase 2 Homo sapiens 37-71 23115809-0 2004 (11)C/(68)Ga-Labeled sel-tagged anti-epidermal growth factor receptor 2 affibody ZHER2:342 The human epidermal growth factor receptor-2 (HER2, ErbB2) modulates its activity through a tyrosine kinase signaling pathway and is involved in the development of various types of cancers (1, 2). Gallium 10-12 erb-b2 receptor tyrosine kinase 2 Homo sapiens 101-135 23115809-0 2004 (11)C/(68)Ga-Labeled sel-tagged anti-epidermal growth factor receptor 2 affibody ZHER2:342 The human epidermal growth factor receptor-2 (HER2, ErbB2) modulates its activity through a tyrosine kinase signaling pathway and is involved in the development of various types of cancers (1, 2). Gallium 10-12 erb-b2 receptor tyrosine kinase 2 Homo sapiens 82-86 23115809-0 2004 (11)C/(68)Ga-Labeled sel-tagged anti-epidermal growth factor receptor 2 affibody ZHER2:342 The human epidermal growth factor receptor-2 (HER2, ErbB2) modulates its activity through a tyrosine kinase signaling pathway and is involved in the development of various types of cancers (1, 2). Gallium 10-12 erb-b2 receptor tyrosine kinase 2 Homo sapiens 143-148 24377605-5 2013 RESULTS: Genotype frequencies of XRCC1 Arg399Gln observed in controls were 34.2%, 42.5% and 23.3% for GG (Arg/Arg), GA (Arg/Gln), AA( Gln/Gln), respectively, and 28.3%, 66.7% and 5% in cases, with an odds ratio (OR)=5.7 and 95% confidence interval (CI) =2.3-14.1 (p=0.0001). Gallium 116-118 X-ray repair cross complementing 1 Homo sapiens 33-38 23020316-7 2012 Furthermore, our cellular and molecular analysis of the GA-response signaling mutants suggest that RGA and GAI are the major repressors regulating GA-induced chloroplast division, but other DELLA proteins (RGL1, RGL2 and RGL3) also play a role in repressing chloroplast division in Arabidopsis. Gallium 56-58 GRAS family transcription factor family protein Arabidopsis thaliana 99-102 23020316-7 2012 Furthermore, our cellular and molecular analysis of the GA-response signaling mutants suggest that RGA and GAI are the major repressors regulating GA-induced chloroplast division, but other DELLA proteins (RGL1, RGL2 and RGL3) also play a role in repressing chloroplast division in Arabidopsis. Gallium 56-58 RGA-like 1 Arabidopsis thaliana 206-210 23020316-7 2012 Furthermore, our cellular and molecular analysis of the GA-response signaling mutants suggest that RGA and GAI are the major repressors regulating GA-induced chloroplast division, but other DELLA proteins (RGL1, RGL2 and RGL3) also play a role in repressing chloroplast division in Arabidopsis. Gallium 56-58 RGA-like 2 Arabidopsis thaliana 212-216 23020316-7 2012 Furthermore, our cellular and molecular analysis of the GA-response signaling mutants suggest that RGA and GAI are the major repressors regulating GA-induced chloroplast division, but other DELLA proteins (RGL1, RGL2 and RGL3) also play a role in repressing chloroplast division in Arabidopsis. Gallium 56-58 RGA-like protein 3 Arabidopsis thaliana 221-225 23136680-0 2004 (68)Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2 Somatostatin (SST) is an inhibitor of the release of somatotropin, glucagon, insulin, gastrointestinal hormones, and other secretory proteins (1). Gallium 4-6 growth hormone 1 Homo sapiens 188-200 23086813-0 2012 GA/GB fold switching may modulate fatty acid transfer from human serum albumin to bacteria. Gallium 0-2 albumin Homo sapiens 65-78 22918762-6 2013 To develop a Bn-like peptide with favorable tumor targeting and pharmacokinetic characteristics for possible clinical use, several modifications in the Bn-like peptides, such as the use of a variety of chelating agents, i.e., acyclic and macrocyclic agents with different spacer groups and with different metal ions (gallium), have been performed in recent years without significant disturbance of the vital binding scaffold. Gallium 317-324 gastrin releasing peptide Homo sapiens 13-15 22885569-4 2012 Experimental results indicate that the XRD peak shift of SnO(2) to a larger angle increases with the increasing amount of Ga doping. Gallium 122-124 strawberry notch homolog 1 Homo sapiens 57-60 23057095-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 120-128 23057095-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 192-217 23057095-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 219-222 23057095-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide receptor Homo sapiens 267-280 23057095-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide receptor Homo sapiens 282-286 23054472-4 2012 Recently, we reported that BPC1 binds to guanine and adenine (GA)-rich consensus sequences in the seedstick (STK) promoter in vitro and induces conformational changes. Gallium 62-64 basic pentacysteine1 Arabidopsis thaliana 27-31 23054472-4 2012 Recently, we reported that BPC1 binds to guanine and adenine (GA)-rich consensus sequences in the seedstick (STK) promoter in vitro and induces conformational changes. Gallium 62-64 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 109-112 23016165-0 2004 (68)Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-1,2-diaminoethane-gamma-5,8-dideazfolic acid (P3238) Folic acid (folate) is a water-soluble B vitamin (1) that is essential for methylation and DNA synthesis. Gallium 4-6 mediator complex subunit 25 Homo sapiens 58-64 23016166-0 2004 (68)Ga-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-1,2-diaminoethane-gamma-folate (P3246) Folic acid (folate) is a water-soluble B vitamin (1) that is essential for methylation and DNA synthesis. Gallium 4-6 mediator complex subunit 25 Homo sapiens 58-64 22885569-6 2012 The maximum quantum efficiency of Ga(2)O(3)/SnO(2):Ga core-shell nanowires is around 0.362%. Gallium 34-36 strawberry notch homolog 1 Homo sapiens 44-47 22885569-6 2012 The maximum quantum efficiency of Ga(2)O(3)/SnO(2):Ga core-shell nanowires is around 0.362%. Gallium 51-53 strawberry notch homolog 1 Homo sapiens 44-47 22885569-7 2012 The UV light on-off current contrast ratio of Ga(2)O(3)/SnO(2):Ga core-shell nanowires is around 1066.7 at a bias of 5 V. Moreover, the dynamic response of Ga(2)O(3)/SnO(2):Ga core-shell nanowires has an on-off current contrast ratio of around 16. Gallium 63-65 strawberry notch homolog 1 Homo sapiens 56-59 22885569-7 2012 The UV light on-off current contrast ratio of Ga(2)O(3)/SnO(2):Ga core-shell nanowires is around 1066.7 at a bias of 5 V. Moreover, the dynamic response of Ga(2)O(3)/SnO(2):Ga core-shell nanowires has an on-off current contrast ratio of around 16. Gallium 63-65 strawberry notch homolog 1 Homo sapiens 166-169 23798936-5 2012 RESULTS: THE FOLLOWING GENOTYPES WERE IDENTIFIED FOR TM: GG in 69.2%, GA in27.2%, and AA in 3.6% of the participants. Gallium 70-72 thrombomodulin Homo sapiens 53-55 22623027-0 2012 Univalent gallium and indium phosphane complexes: from pyramidal M(PPh3)3(+) to carbene-analogous bent M(PtBu3)2(+) (M=Ga, In) complexes. Gallium 10-17 protein phosphatase 4 catalytic subunit Homo sapiens 67-71 22820377-2 2012 Here we show that BR and GA act interdependently through a direct interaction between the BR-activated BZR1 and GA-inactivated DELLA transcription regulators. Gallium 25-27 Brassinosteroid signaling positive regulator (BZR1) family protein Arabidopsis thaliana 103-107 22787691-14 2004 This chapter presents the results obtained with (111)In/(68)Ga-labeled DOTA-cyclo-MG1 ([(111)In/(68)Ga]-DOTA-cyclo-MG1). Gallium 60-62 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 82-85 22787691-14 2004 This chapter presents the results obtained with (111)In/(68)Ga-labeled DOTA-cyclo-MG1 ([(111)In/(68)Ga]-DOTA-cyclo-MG1). Gallium 60-62 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 115-118 22839758-4 2012 We found that the RBM5 RRM2 could preferentially bind to both CU rich and GA rich sequences with affinity in 10(-5) molar range. Gallium 74-76 RNA binding motif protein 5 Homo sapiens 18-22 22839758-4 2012 We found that the RBM5 RRM2 could preferentially bind to both CU rich and GA rich sequences with affinity in 10(-5) molar range. Gallium 74-76 ribonucleotide reductase regulatory subunit M2 Homo sapiens 23-27 22855967-0 2004 (111)In/(68)Ga-Labeled DOTA conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Nle-Asp-Phe-NH2 (cyclo-MG2), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein coupled receptor family and are classified (CCK1R, CCK2R and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues and molecular structure (1). Gallium 12-14 cholecystokinin Homo sapiens 169-172 22855967-0 2004 (111)In/(68)Ga-Labeled DOTA conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Nle-Asp-Phe-NH2 (cyclo-MG2), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein coupled receptor family and are classified (CCK1R, CCK2R and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues and molecular structure (1). Gallium 12-14 cholecystokinin A receptor Homo sapiens 259-264 22855967-0 2004 (111)In/(68)Ga-Labeled DOTA conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Nle-Asp-Phe-NH2 (cyclo-MG2), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein coupled receptor family and are classified (CCK1R, CCK2R and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues and molecular structure (1). Gallium 12-14 cholecystokinin B receptor Homo sapiens 266-271 22855967-0 2004 (111)In/(68)Ga-Labeled DOTA conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Nle-Asp-Phe-NH2 (cyclo-MG2), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein coupled receptor family and are classified (CCK1R, CCK2R and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues and molecular structure (1). Gallium 12-14 cholecystokinin Homo sapiens 185-188 22855967-0 2004 (111)In/(68)Ga-Labeled DOTA conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Nle-Asp-Phe-NH2 (cyclo-MG2), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein coupled receptor family and are classified (CCK1R, CCK2R and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues and molecular structure (1). Gallium 12-14 gastrin Homo sapiens 111-118 22855967-14 2004 This chapter presents the results obtained with (111)In/(68)Ga- labeled DOTA-cyclo-MG2 ([(111)In/(68)Ga]-DOTA-cyclo-MG1). Gallium 60-62 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 116-119 22855967-15 2004 The biodistribution and imaging characteristics of (111)In/(68)Ga- labeled DOTA-cyclo-MG1 are presented in a companion chapter in MICAD (www.micad.nih.gov) (8). Gallium 63-65 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 86-89 22336375-12 2012 The 10-fold higher affinity to SSTR2 of DOTA-TATE as compared to DOTA-TOC known from studies in transfected cells was reflected in a slightly more intense binding of [67/68Ga]Ga-DOTA-TATE than of [67/68Ga]Ga-DOTA-TOC in the monkey brain sections in vitro, but not in vivo in the rat. Gallium 172-174 somatostatin receptor 2 Rattus norvegicus 31-36 22966590-6 2012 These results demonstrate that Ga, In, and Hf doping can effectively enhance the performance of SnO2-based TFT devices. Gallium 31-33 strawberry notch homolog 2 Homo sapiens 96-99 22336375-12 2012 The 10-fold higher affinity to SSTR2 of DOTA-TATE as compared to DOTA-TOC known from studies in transfected cells was reflected in a slightly more intense binding of [67/68Ga]Ga-DOTA-TATE than of [67/68Ga]Ga-DOTA-TOC in the monkey brain sections in vitro, but not in vivo in the rat. Gallium 175-177 somatostatin receptor 2 Rattus norvegicus 31-36 22494113-3 2012 This prompted us to investigate the role of two members of the miR159 family and their putative strawberry target gene, GAMYB, in relation to changes in GA content during the course of fruit development. Gallium 120-122 MIR159b Arabidopsis thaliana 63-69 22531829-1 2012 OBJECTIVE: To prospectively evaluate the role of Ga-labelled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI-octreotide (Ga-DOTA-NOC) PET-CT in patients with recurrent medullary thyroid carcinoma (MTC) and compare the same with F-fluorodeoxyglucose (F-FDG) PET-CT. MATERIALS AND METHODS: Fifty-two consecutive patients with recurrent MTC based on raised serum calcitonin levels underwent Ga-DOTA-NOC PET-CT. Gallium 49-51 nocturnin Homo sapiens 146-149 22787690-0 2004 (68)Ga-Labeled NODAGA-conjugated ghrelin receptor agonists and inverse agonists Ghrelin is a 28-amino-acid peptide hormone that is produced and secreted mainly by the gastric mucosa and triggers the secretion of growth hormone (GH) from the pituitary by binding to the ghrelin receptor (previously known as the GH secretagogue receptor 1a or GHSR1a) (1). Gallium 4-6 growth hormone secretagogue receptor Homo sapiens 33-49 22787690-0 2004 (68)Ga-Labeled NODAGA-conjugated ghrelin receptor agonists and inverse agonists Ghrelin is a 28-amino-acid peptide hormone that is produced and secreted mainly by the gastric mucosa and triggers the secretion of growth hormone (GH) from the pituitary by binding to the ghrelin receptor (previously known as the GH secretagogue receptor 1a or GHSR1a) (1). Gallium 4-6 growth hormone 1 Homo sapiens 212-226 22787690-0 2004 (68)Ga-Labeled NODAGA-conjugated ghrelin receptor agonists and inverse agonists Ghrelin is a 28-amino-acid peptide hormone that is produced and secreted mainly by the gastric mucosa and triggers the secretion of growth hormone (GH) from the pituitary by binding to the ghrelin receptor (previously known as the GH secretagogue receptor 1a or GHSR1a) (1). Gallium 4-6 growth hormone 1 Homo sapiens 228-230 22531829-1 2012 OBJECTIVE: To prospectively evaluate the role of Ga-labelled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI-octreotide (Ga-DOTA-NOC) PET-CT in patients with recurrent medullary thyroid carcinoma (MTC) and compare the same with F-fluorodeoxyglucose (F-FDG) PET-CT. MATERIALS AND METHODS: Fifty-two consecutive patients with recurrent MTC based on raised serum calcitonin levels underwent Ga-DOTA-NOC PET-CT. Gallium 49-51 nocturnin Homo sapiens 413-416 22787690-0 2004 (68)Ga-Labeled NODAGA-conjugated ghrelin receptor agonists and inverse agonists Ghrelin is a 28-amino-acid peptide hormone that is produced and secreted mainly by the gastric mucosa and triggers the secretion of growth hormone (GH) from the pituitary by binding to the ghrelin receptor (previously known as the GH secretagogue receptor 1a or GHSR1a) (1). Gallium 4-6 growth hormone secretagogue receptor Homo sapiens 269-285 22787691-0 2004 (111)In/(68)Ga-Labeled DOTA-conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Met-Asp-Phe-NH2 (cyclo-MG1), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein-coupled receptor family and are classified (CCK1R, CCK2R, and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 12-14 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 99-102 22764389-0 2004 (66)Ga-Labeled PEGylated nano-graphene oxide (GO) covalently linked to NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody TRC105 The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked, homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 92-97 22787691-0 2004 (111)In/(68)Ga-Labeled DOTA-conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Met-Asp-Phe-NH2 (cyclo-MG1), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein-coupled receptor family and are classified (CCK1R, CCK2R, and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 12-14 cholecystokinin Homo sapiens 169-172 22787691-0 2004 (111)In/(68)Ga-Labeled DOTA-conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Met-Asp-Phe-NH2 (cyclo-MG1), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein-coupled receptor family and are classified (CCK1R, CCK2R, and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 12-14 cholecystokinin A receptor Homo sapiens 259-264 22787691-0 2004 (111)In/(68)Ga-Labeled DOTA-conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Met-Asp-Phe-NH2 (cyclo-MG1), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein-coupled receptor family and are classified (CCK1R, CCK2R, and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 12-14 cholecystokinin B receptor Homo sapiens 266-271 22787691-0 2004 (111)In/(68)Ga-Labeled DOTA-conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Met-Asp-Phe-NH2 (cyclo-MG1), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein-coupled receptor family and are classified (CCK1R, CCK2R, and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 12-14 cholecystokinin Homo sapiens 185-188 22787691-0 2004 (111)In/(68)Ga-Labeled DOTA-conjugated cyclo[gamma-d-Glu-Ala-Tyr-d-Lys]-Trp-Met-Asp-Phe-NH2 (cyclo-MG1), a minigastrin analog The three subtypes of the cholecystokinin (CCK) receptors (CCKR) belong to the G-protein-coupled receptor family and are classified (CCK1R, CCK2R, and CCK2i4svR) on the basis of their affinities for the CCK and the gastrin peptides, differential distribution in the tissues, and molecular structure (1). Gallium 12-14 gastrin Homo sapiens 111-118 22680305-9 2012 Because gallium is chemically similar to zinc, it can interfere with the activity of matrix metalloproteinases (zinc-bearing proteases), which have been implicated in the etiology of neuropathic pain, and it may suppress the secretion of substance P. Gallium 8-15 tachykinin precursor 1 Homo sapiens 238-249 22764389-0 2004 (66)Ga-Labeled PEGylated nano-graphene oxide (GO) covalently linked to NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody TRC105 The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked, homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 99-107 22764389-0 2004 (66)Ga-Labeled PEGylated nano-graphene oxide (GO) covalently linked to NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody TRC105 The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked, homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 149-154 22764389-0 2004 (66)Ga-Labeled PEGylated nano-graphene oxide (GO) covalently linked to NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody TRC105 The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked, homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 164-172 22764389-0 2004 (66)Ga-Labeled PEGylated nano-graphene oxide (GO) covalently linked to NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody TRC105 The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked, homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 transforming growth factor, beta 1 Mus musculus 327-335 22764389-14 2004 used PET to evaluate (66)Ga-labeled PEGylated nano-GO covalently linked to NOTA-conjugated TRC105 ([(66)Ga]-NOTA-GO-TRC105) to visualize and target tumors that express the CD105 antigen in mice (15). Gallium 25-27 endoglin Mus musculus 172-177 22621181-0 2012 Gallium-67-labeled lactam bridge-cyclized alpha-MSH peptides with enhanced melanoma uptake and reduced renal uptake. Gallium 0-7 pro-opiomelanocortin-alpha Mus musculus 42-51 22741183-0 2004 (66)Ga-Labeled NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 36-41 22741183-0 2004 (66)Ga-Labeled NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 43-51 22741183-0 2004 (66)Ga-Labeled NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 86-91 22741183-0 2004 (66)Ga-Labeled NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 endoglin Mus musculus 101-109 22741183-0 2004 (66)Ga-Labeled NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked homodimeric transmembrane glycoprotein that is a co-receptor for the transforming growth factor beta (TGF-beta) (1). Gallium 4-6 transforming growth factor, beta 1 Mus musculus 263-271 24750608-1 2012 GA-13315 (13-chlorine-3,15-dioxy-gibberllic acid methyl ester) was semi-synthesized by GA3 (gibberellic acid) as a potential anticancer drug. Gallium 0-2 succinyl-CoA:glutarate-CoA transferase Homo sapiens 87-90 24750608-3 2012 So, GA-13315/CD complexes were prepared with native beta-cyclodextrin and its derivatives (hydroxypropyl-beta-cyclodextrin (HPbetaCD)) and their inclusion complexation behavior, characterization and binding ability in both solution and the solid state was studied by means of UV, XRD, DSC, SEM, (1)H and 2D NMR spectroscopy. Gallium 4-6 desmocollin 3 Homo sapiens 285-288 22669881-9 2012 Our results demonstrate that MYC2 is also connected to GA signaling in regulating a subset of genes. Gallium 55-57 Basic helix-loop-helix (bHLH) DNA-binding family protein Arabidopsis thaliana 29-33 22696780-0 2004 (68)Ga-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12 Epidermal growth factor (EGF) is a 53-amino acid cytokine (6.2 kDa) that is secreted by ectodermic cells, monocytes, kidneys, and duodenal glands (1). Gallium 4-6 epidermal growth factor receptor Mus musculus 51-55 22573618-7 2012 Similarly, impairing GA signalling in the vascular tissue reduces FT and TSF mRNA levels and delays flowering. Gallium 21-23 PEBP (phosphatidylethanolamine-binding protein) family protein Arabidopsis thaliana 73-76 21872645-2 2012 SCOPE OF THE REVIEW: This review deals with the mechanisms of aluminum(III), cobalt(III), uranium(VI), gallium(III) and bismuth(III) uptake by transferrin and interaction with receptor 1. Gallium 103-110 transferrin Homo sapiens 143-154 22015946-6 2012 The genotype frequency for WT1 rs16754 was 6.8% for AA, 39.7% for GA, and 53.4% for GG. Gallium 66-68 WT1 transcription factor Homo sapiens 27-30 22074401-0 2012 Gallium compound GaQ(3) -induced Ca(2+) signalling triggers p53-dependent and -independent apoptosis in cancer cells. Gallium 0-7 tumor protein p53 Homo sapiens 61-64 22349459-5 2012 Genetic study revealed that GA-enhanced hook development was dependent on HOOKLESS 1 (HLS1), a central regulator mediating the input of the multiple signaling pathways during apical hook development. Gallium 28-30 Acyl-CoA N-acyltransferases (NAT) superfamily protein Arabidopsis thaliana 74-84 22349459-5 2012 Genetic study revealed that GA-enhanced hook development was dependent on HOOKLESS 1 (HLS1), a central regulator mediating the input of the multiple signaling pathways during apical hook development. Gallium 28-30 Acyl-CoA N-acyltransferases (NAT) superfamily protein Arabidopsis thaliana 86-90 22445450-4 2012 Under basal conditions glutaric (GA) and 3-OH-glutaric (3OHGA) acids were elevated in all tissues of the Gcdh(-/-) mice, but were essentially absent in WT animals. Gallium 33-35 glutaryl-Coenzyme A dehydrogenase Mus musculus 105-109 22445450-6 2012 Following a single intra-peritoneal (IP) injection of lysine (Lys) there was a moderate increase of brain GA concentration in Gcdh(-/-) mice, but no change in WT. Gallium 106-108 glutaryl-Coenzyme A dehydrogenase Mus musculus 126-130 22553890-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-aminohexanoic acid-Lys(40)-exendin-4 Glucagon-like peptide-1 (GLP-1, 30 amino acids) is secreted from enteroendocrine cells of the distal small intestine in response to food ingestion (1). Gallium 4-6 glucagon Homo sapiens 106-129 22553890-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-aminohexanoic acid-Lys(40)-exendin-4 Glucagon-like peptide-1 (GLP-1, 30 amino acids) is secreted from enteroendocrine cells of the distal small intestine in response to food ingestion (1). Gallium 4-6 glucagon Homo sapiens 131-136 22553890-11 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-aminohexanoic acid-Lys(40)-exendin-4 ([Lys(40)(Ahx-DOTA-(68)Ga)NH2]-exendin-4) is being developed for positron emission tomography (PET) imaging of the GLP-1 receptor (6). Gallium 4-6 glucagon like peptide 1 receptor Homo sapiens 221-235 22286053-3 2012 The ligand formed various monomeric metal complex species MLH3, MLH2, MLH, ML and MLH(-1) with Ga(III) and In(III); MLH3, ML and MLH(-1) with Al(III). Gallium 95-97 mutL homolog 3 Homo sapiens 58-62 22286053-3 2012 The ligand formed various monomeric metal complex species MLH3, MLH2, MLH, ML and MLH(-1) with Ga(III) and In(III); MLH3, ML and MLH(-1) with Al(III). Gallium 95-97 PMS1 homolog 1, mismatch repair system component Homo sapiens 64-68 22286053-3 2012 The ligand formed various monomeric metal complex species MLH3, MLH2, MLH, ML and MLH(-1) with Ga(III) and In(III); MLH3, ML and MLH(-1) with Al(III). Gallium 95-97 mutL homolog 1 Homo sapiens 82-88 22202439-3 2012 We first observed that Ga treatment inhibited the expression of Rankl-induced early differentiation marker genes, while the same treatment performed subsequently did not modify the expression of late differentiation marker genes. Gallium 23-25 TNF superfamily member 11 Homo sapiens 64-69 22202439-5 2012 We next demonstrated that Ga strongly up-regulated the expression of Traf6, p62 and Cyld genes, and we observed concomitantly an inhibition of IkappaB degradation and a blockade of NFkappaB nuclear translocation, which regulates the initial induction of Nfatc1 gene expression. Gallium 26-28 TNF receptor associated factor 6 Homo sapiens 69-74 22202439-5 2012 We next demonstrated that Ga strongly up-regulated the expression of Traf6, p62 and Cyld genes, and we observed concomitantly an inhibition of IkappaB degradation and a blockade of NFkappaB nuclear translocation, which regulates the initial induction of Nfatc1 gene expression. Gallium 26-28 nucleoporin 62 Homo sapiens 76-79 22202439-5 2012 We next demonstrated that Ga strongly up-regulated the expression of Traf6, p62 and Cyld genes, and we observed concomitantly an inhibition of IkappaB degradation and a blockade of NFkappaB nuclear translocation, which regulates the initial induction of Nfatc1 gene expression. Gallium 26-28 CYLD lysine 63 deubiquitinase Homo sapiens 84-88 22202439-5 2012 We next demonstrated that Ga strongly up-regulated the expression of Traf6, p62 and Cyld genes, and we observed concomitantly an inhibition of IkappaB degradation and a blockade of NFkappaB nuclear translocation, which regulates the initial induction of Nfatc1 gene expression. Gallium 26-28 nuclear factor kappa B subunit 1 Homo sapiens 181-189 22202439-5 2012 We next demonstrated that Ga strongly up-regulated the expression of Traf6, p62 and Cyld genes, and we observed concomitantly an inhibition of IkappaB degradation and a blockade of NFkappaB nuclear translocation, which regulates the initial induction of Nfatc1 gene expression. Gallium 26-28 nuclear factor of activated T cells 1 Homo sapiens 254-260 22202439-6 2012 In addition, Ga inhibited c-Fos gene expression, and subsequently the auto-amplification stage of Nfatc1 gene expression. Gallium 13-15 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 26-31 22202439-7 2012 Lastly, considering calcium signaling, we observed upon Ga treatment an inhibition of calcium-induced Creb phosphorylation, as well as a blockade of gadolinium-induced calcium entry through TRPV-5 calcium channels. Gallium 56-58 cAMP responsive element binding protein 1 Homo sapiens 102-106 22202439-9 2012 In addition, our results strongly suggest that the TRPV-5 calcium channel, which is located within the plasma membrane, is a target of Ga action on human osteoclast progenitor cells. Gallium 135-137 transient receptor potential cation channel subfamily V member 5 Homo sapiens 51-57 22227336-10 2012 Results from this study may imply that GA could counteract the development of type 2 diabetes mellitus by improving insulin sensitivity and probably by reduction of H6PDH, 11beta-HSD1 and a selective decrease in PEPCK activities. Gallium 39-41 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Rattus norvegicus 165-170 22227336-10 2012 Results from this study may imply that GA could counteract the development of type 2 diabetes mellitus by improving insulin sensitivity and probably by reduction of H6PDH, 11beta-HSD1 and a selective decrease in PEPCK activities. Gallium 39-41 hydroxysteroid 11-beta dehydrogenase 1 Rattus norvegicus 172-183 22227336-10 2012 Results from this study may imply that GA could counteract the development of type 2 diabetes mellitus by improving insulin sensitivity and probably by reduction of H6PDH, 11beta-HSD1 and a selective decrease in PEPCK activities. Gallium 39-41 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus 212-217 22080333-0 2012 Low valent and hydride complexes of NHC coordinated gallium and indium. Gallium 52-59 high mobility group nucleosomal binding domain 4 Homo sapiens 36-39 22264762-5 2012 (68)Ga-DOTA-4-FBn-TN14003 was reproducibly obtained in isolated radiochemical yields of 72.5+-4.9% with an excellent radiochemical purity of >99.5%. Gallium 4-6 fibrillin 1 Homo sapiens 14-17 21643957-8 2012 These results suggest that the expression of BnGID1a and BnSLY1 may be negatively regulated by the level of endogenous GA in B. napus. Gallium 119-121 F-box protein GID2 Brassica napus 57-63 22122546-6 2012 KYP/SUVH4 expression is regulated by abscisic acid (ABA) and gibberellins (GA). Gallium 75-77 histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4-like protein Arabidopsis thaliana 0-3 22122546-6 2012 KYP/SUVH4 expression is regulated by abscisic acid (ABA) and gibberellins (GA). Gallium 75-77 histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4-like protein Arabidopsis thaliana 4-9 22567844-6 2012 Furthermore, CKMM AA genotype was associated with high values of VO2(max) (AA - 58.98 (3.44) ml/kg/min, GA - 56.99 (4.36) ml/kg/min, GG - 52.87 (4.32) ml/kg/min, p = 0.0097). Gallium 104-106 creatine kinase, M-type Homo sapiens 13-17 23133809-1 2012 The carcinoembryonic antigen (CEA) was visualized in vitro in tissue from patients with colorectal cancer with trivalent bispecific antibody TF2 and two hapten molecules, [(67/68)Ga]Ga-IMP461 and [(67/68)Ga]Ga-IMP485 by means of pretargeting. Gallium 179-181 CEA cell adhesion molecule 3 Homo sapiens 4-28 23133809-1 2012 The carcinoembryonic antigen (CEA) was visualized in vitro in tissue from patients with colorectal cancer with trivalent bispecific antibody TF2 and two hapten molecules, [(67/68)Ga]Ga-IMP461 and [(67/68)Ga]Ga-IMP485 by means of pretargeting. Gallium 179-181 CEA cell adhesion molecule 3 Homo sapiens 30-33 22616033-1 2012 Gallium-67 localization is based on the fact that it binds to plasma proteins like transferrin and lactoferrin, which have iron-binding sites. Gallium 0-7 transferrin Homo sapiens 83-94 22147338-0 2011 TRAP, a powerful and versatile framework for gallium-68 radiopharmaceuticals. Gallium 45-52 TRAP Homo sapiens 0-4 21858448-7 2012 GA-treatment induced transcript accumulation of members of both alpha-amylase groups, as well as alpha- and beta-amylase enzyme activity in sprout and "sub-eye" tissues. Gallium 0-2 alpha-amylase Solanum tuberosum 64-77 21858448-7 2012 GA-treatment induced transcript accumulation of members of both alpha-amylase groups, as well as alpha- and beta-amylase enzyme activity in sprout and "sub-eye" tissues. Gallium 0-2 alpha-amylase Solanum tuberosum 97-120 21858448-8 2012 In sprouts, CAR interacts with the GA-mediated accumulation of alpha-amylase transcripts in an alpha-AMY2-specific and dose-dependent manner. Gallium 35-37 alpha-amylase Solanum tuberosum 63-76 22099153-3 2011 In this study we analyzed abundances miRNA-125b and miRNA-146a in magnesium-, iron-, gallium, and aluminum-sulfate-stressed human-astroglial (HAG) cells, a structural and immune-responsive brain cell type. Gallium 85-92 microRNA 146a Homo sapiens 52-62 21963238-6 2011 HOTAIR lncRNA preferentially occupies a GA-rich DNA motif to nucleate broad domains of Polycomb occupancy and histone H3 lysine 27 trimethylation. Gallium 40-42 HOX transcript antisense RNA Homo sapiens 0-6 22091478-16 2004 (10) have investigated the potential of (68)Ga-DOTA-MG0 for positron emission tomography (PET) CCK2R-expressing tumors in nude mice. Gallium 44-46 cholecystokinin B receptor Mus musculus 95-100 21554205-6 2011 Because gallium absorbed from orally administered GaM is bound predominately to serum transferrin, which travels to all tissues in the body, GaM has the potential to treat even distant metastases. Gallium 8-15 transferrin Homo sapiens 86-97 22045709-0 2011 PET of CXCR4 expression by a (68)Ga-labeled highly specific targeted contrast agent. Gallium 33-35 C-X-C motif chemokine receptor 4 Homo sapiens 7-12 21771122-5 2011 Here, we show that LA activity is mediated in part by GA. Gallium 54-56 cycloidea Solanum lycopersicum 19-21 21771122-6 2011 Expression of the SlGA20 oxidase1 (SlGA20ox1) gene, which encodes an enzyme in the GA biosynthesis pathway, is increased in gain-of-function La mutants and reduced in plants that over-express miR319. Gallium 20-22 microRNA MIR319 Solanum lycopersicum 192-198 21771122-8 2011 The miR319 over-expression phenotype is suppressed by exogenous GA application and by a mutation in the PROCERA (PRO) gene, which encodes an inhibitor of the GA response. Gallium 64-66 microRNA MIR319 Solanum lycopersicum 4-10 21771122-8 2011 The miR319 over-expression phenotype is suppressed by exogenous GA application and by a mutation in the PROCERA (PRO) gene, which encodes an inhibitor of the GA response. Gallium 158-160 microRNA MIR319 Solanum lycopersicum 4-10 21850779-0 2004 Gallium-68-dotamaleimide-Cys165-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys165-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys165-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 47-54 annexin A5 Homo sapiens 32-42 21850779-0 2004 Gallium-68-dotamaleimide-Cys165-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys165-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys165-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 47-54 annexin A5 Homo sapiens 100-105 21850779-0 2004 Gallium-68-dotamaleimide-Cys165-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys165-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys165-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 47-54 annexin A5 Homo sapiens 147-152 21850779-0 2004 Gallium-68-dotamaleimide-Cys165-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys165-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys165-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 0-2 annexin A5 Homo sapiens 32-42 21850779-0 2004 Gallium-68-dotamaleimide-Cys165-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys165-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys165-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 0-2 annexin A5 Homo sapiens 100-105 21850779-0 2004 Gallium-68-dotamaleimide-Cys165-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys165-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys165-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 0-2 annexin A5 Homo sapiens 147-152 21850779-22 2004 synthesized two radionuclide agents, (68)Ga-Cys2-AnxA5 and (68)Ga-Cys165-AnxA5 (1). Gallium 63-65 annexin A5 Homo sapiens 73-78 21850779-27 2004 showed that both (68)Ga-Cys2-AnxA5 and (68)Ga-Cys165-AnxA5 exhibit a clear binding to apoptotic cells and are promising tracers for the rapid evaluation of cancer therapy (1). Gallium 21-23 annexin A5 Homo sapiens 29-34 21850781-0 2004 Gallium-68-dotamaleimide-Cys2-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys2-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys2-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 45-52 annexin A5 Homo sapiens 30-40 21850781-0 2004 Gallium-68-dotamaleimide-Cys2-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys2-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys2-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 45-52 annexin A5 Homo sapiens 96-101 21850781-0 2004 Gallium-68-dotamaleimide-Cys2-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys2-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys2-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 45-52 annexin A5 Homo sapiens 141-146 21850781-0 2004 Gallium-68-dotamaleimide-Cys2-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys2-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys2-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 0-2 annexin A5 Homo sapiens 30-40 21850781-0 2004 Gallium-68-dotamaleimide-Cys2-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys2-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys2-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 0-2 annexin A5 Homo sapiens 96-101 21850781-0 2004 Gallium-68-dotamaleimide-Cys2-annexin A5 The gallium-68 ((68)Ga)-dotamaleimide-Cys2-annexin A5 (AnxA5) conjugate, abbreviated as (68)Ga-Cys2-AnxA5, is a radionuclide agent developed by Bauwens et al. Gallium 0-2 annexin A5 Homo sapiens 141-146 21850781-22 2004 synthesized two radionuclide agents, (68)Ga-Cys2-AnxA5 and (68)Ga-Cys165-AnxA5 (1). Gallium 63-65 annexin A5 Homo sapiens 73-78 21850781-27 2004 showed that both (68)Ga-Cys2-AnxA5 and (68)Ga-Cys165-AnxA5 exhibit a clear binding to apoptotic cells and are promising tracers for the rapid evaluation of cancer therapy (1). Gallium 21-23 annexin A5 Homo sapiens 29-34 21535259-4 2011 The level of GA activity determines the speed of hook formation and the extent of the curvature during the formation phase independently of ethylene, probably by modulating auxin transport and response through HLS1, PIN3, and PIN7. Gallium 13-15 Acyl-CoA N-acyltransferases (NAT) superfamily protein Arabidopsis thaliana 210-214 21535259-4 2011 The level of GA activity determines the speed of hook formation and the extent of the curvature during the formation phase independently of ethylene, probably by modulating auxin transport and response through HLS1, PIN3, and PIN7. Gallium 13-15 Auxin efflux carrier family protein Arabidopsis thaliana 216-220 21535259-4 2011 The level of GA activity determines the speed of hook formation and the extent of the curvature during the formation phase independently of ethylene, probably by modulating auxin transport and response through HLS1, PIN3, and PIN7. Gallium 13-15 Auxin efflux carrier family protein Arabidopsis thaliana 226-230 21834177-0 2004 (68)Ga-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-2-(2-nitroimidazolyl)ethylamine Hypoxia is found in a variety of solid tumors and leads to tumor progression and resistance to chemotherapy and radiotherapy (1, 2). Gallium 4-6 PTOV1 extended AT-hook containing adaptor protein Homo sapiens 55-61 20824508-13 2011 CONCLUSIONS: Two (68)Ga-labeled ligands appear to be valuable for imaging non-invasively the intratumoral Pgp activity. Gallium 21-23 ATP binding cassette subfamily B member 1 Homo sapiens 106-109 21718947-2 2011 Herein, we report on preclinical results using a novel DOTA-Bz-EDA-folate conjugate radiolabeled with [(67)Ga]-gallium. Gallium 111-118 ectodysplasin-A Mus musculus 63-66 21553855-7 2011 The kinetic parameters for phosphite dianion activation of the reactions of [1-(13)C]-GA catalyzed by wildtype Tbb TIM are similar to those reported for the enzyme from rabbit muscle [Amyes, T. L. and Richard, J. P. (2007) Biochemistry 46, 5841-5854], but there is no detectable dianion activation of the reaction catalyzed by monoTIM. Gallium 86-88 triosephosphate isomerase Oryctolagus cuniculus 115-118 21382684-2 2011 In this investigation, the MEEKC technique was applied for estimation of n-octanol-water partition coefficient (logP(oct)) of a series of antiproliferative complexes of gallium(III) and iron(III) with (4)N-substituted alpha-N-heterocyclic thiosemicarbazones. Gallium 169-176 plexin A2 Homo sapiens 75-78 21382684-5 2011 Extension of the logP(oct) programs by adding DeltalogP(oct) data resulted in good lipophilicity predictions for the complexes of gallium(III) and iron(III) included in one regression set. Gallium 130-137 plexin A2 Homo sapiens 22-25 21382684-5 2011 Extension of the logP(oct) programs by adding DeltalogP(oct) data resulted in good lipophilicity predictions for the complexes of gallium(III) and iron(III) included in one regression set. Gallium 130-137 plexin A2 Homo sapiens 46-60 21463326-7 2011 The mean probing depth in patients carrying the AA genotype was significantly higher than that of patients carrying the GA + GG genotype of two polymorphisms of S100A8 (rs3795391, p = 0.035; rs3806232, p = 0.040), whereas the levels of calprotectin between different genotypes were not significantly different (rs3795391, p = 0.11; rs3806232, p = 0.15). Gallium 120-122 S100 calcium binding protein A8 Homo sapiens 161-167 20567846-6 2011 Moreover, the GA+AA genotype of the RIPK1 rs2272990 and the GG genotype of the CASP7 rs2227310 were significantly correlated with a worse disease-free (hazard ratio [HR] = 2.093; P = 0.007 and HR = 2.641; 0.002, respectively) and disease-specific survival (HR = 2.222; P = 0.013 and HR = 2.247; P = 0.031, respectively) in a multivariate survival analysis. Gallium 14-16 receptor interacting serine/threonine kinase 1 Homo sapiens 36-41 21634076-0 2004 (67/68)Ga-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-1,2-diaminoethane-gamma-folate Folic acid (folate) is a water-soluble B vitamin (1) that is essential for methylation and DNA synthesis. Gallium 7-9 mediator complex subunit 25 Homo sapiens 58-64 21571950-8 2011 Furthermore, GA treatment resulted in a skotomorphogenic-like phenotype in light-grown 2x35S:ENY and RAB18:ENY seedlings. Gallium 13-15 RAB GTPASE HOMOLOG B18 Arabidopsis thaliana 101-106 21390401-3 2011 It was found that in the reduced gallium-modified mordenite (Ga-MOR) both Ga(3+) and Ga(+) exchanged cations are present and can be detected by CO adsorption. Gallium 33-40 opioid receptor mu 1 Homo sapiens 64-67 21390401-3 2011 It was found that in the reduced gallium-modified mordenite (Ga-MOR) both Ga(3+) and Ga(+) exchanged cations are present and can be detected by CO adsorption. Gallium 61-63 opioid receptor mu 1 Homo sapiens 64-67 21390401-6 2011 It was found, however, that Ga(3+) intrazeolite exchanged cations which form upon high-temperature disproportionation of Ga(+) cations in the reduced Ga-MFI and Ga-MOR can be stabilized by high-temperature oxidation of these zeolites. Gallium 28-30 opioid receptor mu 1 Homo sapiens 164-167 21390401-6 2011 It was found, however, that Ga(3+) intrazeolite exchanged cations which form upon high-temperature disproportionation of Ga(+) cations in the reduced Ga-MFI and Ga-MOR can be stabilized by high-temperature oxidation of these zeolites. Gallium 121-123 opioid receptor mu 1 Homo sapiens 164-167 21492787-7 2011 CONCLUSION: Both (68)Ga-Cys2-AnxA5 and (68)Ga-Cys165-AnxA5 show a clear binding to apoptotic cells and are promising tracers for rapid evaluation of cancer therapy. Gallium 21-23 annexin A5 Mus musculus 29-34 21421412-9 2011 However, phenotypes shown in the ftl1-1D/ddf1 were restored by treatment with exogenous gibberellin (GA3), indicating the involvement of a GA pathway in FTL1/DDF1-mediated tolerance. Gallium 101-103 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 41-45 21421412-9 2011 However, phenotypes shown in the ftl1-1D/ddf1 were restored by treatment with exogenous gibberellin (GA3), indicating the involvement of a GA pathway in FTL1/DDF1-mediated tolerance. Gallium 101-103 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 158-162 21711801-0 2011 Gallium hydride vapor phase epitaxy of GaN nanowires. Gallium 0-7 gigaxonin Homo sapiens 39-42 21711801-4 2011 The increase in growth rate with H2 content is a direct consequence of the reaction of Ga with H2 which leads to the formation of Ga hydride that reacts efficiently with NH3 at the top of the GaN NWs. Gallium 87-89 gigaxonin Homo sapiens 192-195 21492787-7 2011 CONCLUSION: Both (68)Ga-Cys2-AnxA5 and (68)Ga-Cys165-AnxA5 show a clear binding to apoptotic cells and are promising tracers for rapid evaluation of cancer therapy. Gallium 43-45 annexin A5 Mus musculus 53-58 21348056-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-polyethylene glycol-single-chain Cys-tagged vascular endothelial growth factor-121 Vascular endothelial growth factor (VEGF) consists of at least six isoforms with various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 96-130 21348056-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-polyethylene glycol-single-chain Cys-tagged vascular endothelial growth factor-121 Vascular endothelial growth factor (VEGF) consists of at least six isoforms with various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 135-169 21348057-12 2004 In this chapter, (68)Ga-N,N"-bis[2-Hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid-PEG-scVEGF ((68)Ga-HBED-CC-PEG-scVEGF) is being developed for positron emission tomography (PET) imaging of VEGFR-2 in tumor vasculature (10). Gallium 21-23 kinase insert domain receptor Homo sapiens 209-216 21348056-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-polyethylene glycol-single-chain Cys-tagged vascular endothelial growth factor-121 Vascular endothelial growth factor (VEGF) consists of at least six isoforms with various numbers of amino acids (121, 145, 165, 183, 189, and 206 amino acids) produced through alternative splicing (1). Gallium 4-6 vascular endothelial growth factor A Homo sapiens 171-175 20799032-12 2011 PET/CT images, performed with (68)Ga-P3026, showed high uptake in the kidneys and clear visualization of the FR-positive tumours. Gallium 34-36 thyroid stimulating hormone receptor Mus musculus 0-3 21245327-13 2011 Our data further show that SCL3 and DELLA antagonize each other in controlling both downstream GA responses and upstream GA biosynthetic genes. Gallium 95-97 scarecrow-like 3 Arabidopsis thaliana 27-31 21245327-13 2011 Our data further show that SCL3 and DELLA antagonize each other in controlling both downstream GA responses and upstream GA biosynthetic genes. Gallium 121-123 scarecrow-like 3 Arabidopsis thaliana 27-31 21057316-8 2011 MEASUREMENTS AND MAIN RESULTS: We measured plasma albumin and transferrin levels and determined the Gallium-transferrin pulmonary leak index, the American European Consensus Conference criteria, and the lung injury score. Gallium 100-107 transferrin Homo sapiens 108-119 21223390-0 2011 The Arabidopsis tandem zinc finger protein AtTZF1 affects ABA- and GA-mediated growth, stress and gene expression responses. Gallium 67-69 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 43-49 21223390-7 2011 The developmental phenotypes of plants over-expressing AtTZF1 were only partially rescued by exogenous application of GA, implying a reduction in the GA response or defects in other mechanisms. Gallium 118-120 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 55-61 21223390-10 2011 Notably, a gene network centered on a GA-inducible and ABA/sugar-repressible putative peptide hormone encoded by GASA6 was severely repressed by AtTZF1 over-expression. Gallium 38-40 Gibberellin-regulated family protein Arabidopsis thaliana 113-118 21223390-10 2011 Notably, a gene network centered on a GA-inducible and ABA/sugar-repressible putative peptide hormone encoded by GASA6 was severely repressed by AtTZF1 over-expression. Gallium 38-40 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 145-151 20830741-3 2010 The aim of the present study was to examine whether Ga-Al-As laser irradiation could enhance BMP2-induced alkaline phosphatase (ALP) activity in C2C12 cells. Gallium 52-54 bone morphogenetic protein 2 Mus musculus 93-97 21089232-0 2004 (68)Ga-Labeled anti-EpCAM diabody against epithelial cell adhesion molecule Epithelial cell adhesion molecules (EpCAM) are found on the cell surface of epithelial cells of many epithelial tissues such as the pancreas, jejunum, colon, kidney, salivary gland, and prostate (1). Gallium 4-6 epithelial cell adhesion molecule Homo sapiens 20-25 21089232-0 2004 (68)Ga-Labeled anti-EpCAM diabody against epithelial cell adhesion molecule Epithelial cell adhesion molecules (EpCAM) are found on the cell surface of epithelial cells of many epithelial tissues such as the pancreas, jejunum, colon, kidney, salivary gland, and prostate (1). Gallium 4-6 epithelial cell adhesion molecule Homo sapiens 112-117 20977253-4 2010 Thus, in these GaX(2) complexes, the gallyl ligand behaves predominantly as a sigma donor, and the short M-Ga bond lengths can be attributed to high gallium s-orbital character in the M-Ga sigma-bonding orbitals. Gallium 149-156 MAX dimerization protein MGA Homo sapiens 105-109 20977253-4 2010 Thus, in these GaX(2) complexes, the gallyl ligand behaves predominantly as a sigma donor, and the short M-Ga bond lengths can be attributed to high gallium s-orbital character in the M-Ga sigma-bonding orbitals. Gallium 149-156 MAX dimerization protein MGA Homo sapiens 184-188 21086574-0 2004 (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-synthetic HER2 specific Affibody ZHER2:342-pep2 Epidermal growth factor (EGF) is a 53-amino acid cytokine (6.2 kDa) that is secreted by ectodermic cells, monocytes, kidneys and duodenal glands (1). Gallium 4-6 erb-b2 receptor tyrosine kinase 2 Homo sapiens 79-83 22174625-9 2011 Moreover, we found that TaHO1 mRNA could be differentially induced by the well-known nitric oxide (NO) donor sodium nitroprusside (SNP), gibberellin acid (GA), abscisic acid (ABA), hydrogen peroxide (H(2)O(2)) and NaCl treatments. Gallium 155-157 heme oxygenase 1, chloroplastic Triticum aestivum 24-29 20797999-3 2011 Meanwhile, HO activity and HO-1 protein expression exhibited lower levels in GA-treated layers, whereas the hydrogen peroxide (H(2)O(2)) content was apparently increased. Gallium 77-79 heme oxygenase 1, chloroplastic Triticum aestivum 27-31 20797999-6 2011 The application of the HO-1 inducer, haematin, and the enzymatic reaction product of HO, carbon monoxide (CO) aqueous solution, both of which brought about a noticeable induction of HO expression, substantially prevented GA-induced PCD. Gallium 221-223 heme oxygenase 1, chloroplastic Triticum aestivum 23-27 20238169-8 2011 Semi-quantitative RT-PCR showed that GhWRKY3 is up-regulated by application of various phytohormones including salicylic acid (SA), methyl jasmonate (MeJA), abscisic acid (ABA), gibberellins (GAs) and ethylene (ET). Gallium 192-195 probable WRKY transcription factor 3 Gossypium hirsutum 37-44 22102866-2 2011 The paralog GATA transcription factors GNC and CGA1/GNL up-regulated by light, nitrogen and cytokinin while also being repressed by GA signaling. Gallium 12-14 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 39-42 22102866-2 2011 The paralog GATA transcription factors GNC and CGA1/GNL up-regulated by light, nitrogen and cytokinin while also being repressed by GA signaling. Gallium 12-14 cytokinin-responsive gata factor 1 Arabidopsis thaliana 47-55 21278461-5 2011 As the test results, it was found that GA level in actual river water varied widely from less than the determination limit of 23 [1/L] to 1,100 [1/L] by quantitative comparison, and the value was also equivalent to more than 50 times the level of tap water. Gallium 39-41 nuclear RNA export factor 1 Homo sapiens 247-250 21098733-8 2010 Substitution of the loop region or a few amino acids of At GID1b with those of At GID1a diminished its GA-independent interaction with GAI while maintaining the GA-dependent interaction. Gallium 103-105 gibberellin receptor GID1B Brassica napus 59-64 20510679-7 2010 Reactivity increased from Ortho-4 to Ortho-6 for PXE- and VX-inhibited hAChE and from Ortho-4 to Ortho-7 for GA-inhibited hAChE and decreased again with Ortho-8 and Ortho-9. Gallium 109-111 acetylcholinesterase (Cartwright blood group) Homo sapiens 122-127 20430474-5 2010 In addition, we found that GA 3-oxidase 1 (GA3ox1), encoding a key enzyme involved in endogenous bioactive GA biosynthesis, was up-regulated by sucrose in the dark, whereas GIBBERELLIN INSENSITIVE DWARF 1a (AtGID1a), encoding a GA receptor and playing an important role during GAs degradation to DELLA proteins (DELLAs, repressors of GA-induced plant growth), was down-regulated. Gallium 27-29 gibberellin 3-oxidase 1 Arabidopsis thaliana 43-49 20593813-10 2010 In the GaX(2) ligands, gallium dominantly behaves as a sigma donor. Gallium 23-30 mesenchyme homeobox 2 Homo sapiens 7-10 20646200-2 2010 Gallium maltolate (GaM) provides significant gallium bioavailability to people and mice following oral administration and to neonatal foals following intragastric administration. Gallium 45-52 glutaminase Homo sapiens 19-22 20457603-5 2010 We found that MAZ specifically binds to the duplex and quadruplex conformations of the GA-element, whereas PARP-1 shows specificity only for the G-quadruplex. Gallium 87-89 MYC-associated zinc finger protein (purine-binding transcription factor) Mus musculus 14-17 20221582-10 2010 A yeast two-hybrid assay confirmed that this mutation inhibited the interaction between Bnrga-ds/Atrga-ds and the GA receptor, AtGID1A, in the presence of GA(3), suggesting that the conserved proline residue in the VHYNP motif of DELLA protein directly participates in DELLA-GID1 interaction. Gallium 114-116 DELLA protein RGA2 Brassica napus 88-93 20505882-4 2010 METHODS: gallium(III) complexes (5a and 5b) possessing octahedral geometry were synthesized, analytically characterized, and evaluated for their potential to serve as probes of Pgp-mediated functional transport activity in cellulo and in vivo. Gallium 9-16 phosphoglycolate phosphatase Homo sapiens 177-180 20149476-3 2010 To address these questions, three GA 20-oxidase homologous genes (GhGA20ox1-3) were cloned and the endogenous bioactive GA content in developing ovules and fibers determined by liquid chromatography-electrospray ionization-mass spectrometry. Gallium 34-36 auxin-responsive protein SAUR32 Gossypium hirsutum 66-77 20149476-6 2010 Transgenic cotton, over-expressing GhGA20ox1, showed GA over-production phenotypes with increased endogenous GA levels (especially GA(4)) in fibers and ovules. Gallium 53-55 auxin-responsive protein SAUR32 Gossypium hirsutum 35-44 20149476-6 2010 Transgenic cotton, over-expressing GhGA20ox1, showed GA over-production phenotypes with increased endogenous GA levels (especially GA(4)) in fibers and ovules. Gallium 53-55 auxin-responsive protein SAUR32 Gossypium hirsutum 35-44 20221582-10 2010 A yeast two-hybrid assay confirmed that this mutation inhibited the interaction between Bnrga-ds/Atrga-ds and the GA receptor, AtGID1A, in the presence of GA(3), suggesting that the conserved proline residue in the VHYNP motif of DELLA protein directly participates in DELLA-GID1 interaction. Gallium 114-116 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 127-134 19427761-2 2010 METHODS: Pulmonary permeability was measured by the pulmonary leak index (PLI) for (67)gallium-labeled transferrin and EVLW and blood volumes by the transpulmonary indicator dilution technique in 20 mechanically ventilated patients, before and after fluid loading, guided by changes in central venous pressure. Gallium 87-94 transferrin Homo sapiens 103-114 20486702-2 2010 The reactions proceed with addition of the alkynes across the Ga-N-C fragment resulting in carbon-carbon and carbon-gallium bonds. Gallium 116-123 glucosidase alpha, neutral C Homo sapiens 62-68 20302929-9 2010 In conclusion, our results indicate a low but specific efflux transport for GA, 3-OH-GA, and MMA across pBCEC, an in vitro model of the BBB, via OAT1 and OAT3 but not across hCPEC, an in vitro model of the choroid plexus. Gallium 76-78 solute carrier family 22 member 6 Homo sapiens 145-149 20302929-9 2010 In conclusion, our results indicate a low but specific efflux transport for GA, 3-OH-GA, and MMA across pBCEC, an in vitro model of the BBB, via OAT1 and OAT3 but not across hCPEC, an in vitro model of the choroid plexus. Gallium 76-78 solute carrier family 22 member 8 Homo sapiens 154-158 20437086-0 2010 Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. Glutaryl-CoA dehydrogenase deficiency or glutaric acidemia type I (GA I) is an inherited neurometabolic disorder biochemically characterized by tissue accumulation of predominantly glutaric (GA) and 3-hydroxyglutaric (3OHGA) acids and clinically by severe neurological symptoms and structural brain abnormalities, manifested as progressive cerebral atrophy and acute striatum degeneration following encephalopathic crises, whose pathophysiology is still in debate. Gallium 186-188 S100 calcium binding protein B Homo sapiens 13-18 20388661-8 2010 Plant decapitation also produced changes in transcript levels of genes encoding enzymes of GA biosynthesis (SlCPS and SlGA20ox1) in the ovary, quite similar to those found in NPA-induced fruits. Gallium 91-93 copalyl diphosphate synthase Solanum lycopersicum 108-113 20396901-6 2010 Furthermore, we found that the expression of a key enzyme for GA biosynthesis, AtGA20ox3, was downregulated obviously in AtTudor2 T-DNA insertion mutant and AtTudor1/AtTudor2 RNAi transgenic lines. Gallium 62-64 gibberellin 20-oxidase 3 Arabidopsis thaliana 79-88 20396901-6 2010 Furthermore, we found that the expression of a key enzyme for GA biosynthesis, AtGA20ox3, was downregulated obviously in AtTudor2 T-DNA insertion mutant and AtTudor1/AtTudor2 RNAi transgenic lines. Gallium 62-64 TUDOR-SN protein 2 Arabidopsis thaliana 121-129 20396901-6 2010 Furthermore, we found that the expression of a key enzyme for GA biosynthesis, AtGA20ox3, was downregulated obviously in AtTudor2 T-DNA insertion mutant and AtTudor1/AtTudor2 RNAi transgenic lines. Gallium 62-64 TUDOR-SN protein 1 Arabidopsis thaliana 157-165 20396901-6 2010 Furthermore, we found that the expression of a key enzyme for GA biosynthesis, AtGA20ox3, was downregulated obviously in AtTudor2 T-DNA insertion mutant and AtTudor1/AtTudor2 RNAi transgenic lines. Gallium 62-64 TUDOR-SN protein 2 Arabidopsis thaliana 166-174 24900199-0 2010 Synthesis of a (68)ga-labeled peptoid-Peptide hybrid for imaging of neurotensin receptor expression in vivo. Gallium 19-21 neurotensin Mus musculus 68-79 20685471-1 2010 A new gallium (Ga(III)) ion-imprinted multi-walled carbon nanotubes (CNTs) composite sorbent was synthesized by a surface imprinting technique. Gallium 6-13 l(2)46Cc Drosophila melanogaster 15-22 19639269-4 2010 The beneficial effects of gallium supplementation on improvement of cage layer osteoporosis were attributable mainly to decrease TRAP activity, C-terminal crosslinked telopeptides of collagen type I level, plasma calcium and phosphate concentrations, and increase the mineral content in the bones and osteocalcin level in plasma. Gallium 26-33 bone gamma-carboxyglutamate protein Gallus gallus 301-312 20379501-3 2010 A fine beam of Ga(+) ions, applying different doses, damages/removes these SAMs to correspondingly form a pattern containing sets of lines. Gallium 15-17 methionine adenosyltransferase 1A Homo sapiens 75-79 20208118-1 2010 Pt contact on p-Si nanowires (NWs) using Ga-ion-induced deposition by a focused ion beam was formed with a specific contact resistance (rho(c)) of 1.54 x 10(-6) Omega cm(2). Gallium 41-43 ras homolog family member C Homo sapiens 136-142 20397300-8 2010 Ga also dramatically reduced the formation of TRAP-positive multinucleated cells. Gallium 0-2 acid phosphatase 5, tartrate resistant Mus musculus 46-50 20162198-0 2010 Synthesis and in situ transformation of PST-1: a potassium gallosilicate natrolite with a high Ga content. Gallium 95-97 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Homo sapiens 40-45 20162198-1 2010 The synthetic details of a novel potassium gallosilicate natrolite with Si/Ga = 1.28, denoted PST-1, are described. Gallium 75-77 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Homo sapiens 94-99 20162198-3 2010 PST-1 transforms rapidly into TNU-6 under hydrothermal conditions, behaviour that contrasts sharply with its very high thermal and hydrothermal stability, which is unusual for a material of such a high Ga content. Gallium 202-204 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Homo sapiens 0-5 19757159-6 2010 The expression of BnSLY1 under exogenous gibberellins acid-3 (GA3), abscisic acid (ABA) and GA biosynthetic inhibitor paclobutrazol (PAC) was analyzed using real-time PCR. Gallium 62-64 F-box protein GID2 Brassica napus 18-24 20384132-9 2010 The aforementioned experimental results will not only provide some guides to investigate the effects of fusion partner Trx on the unfolding thermodynamics, kinetics and refolding process of Trx-GcGASA, but also will be useful for further studies on the strucuture of GA-induced cysteine-rich protein with the help of spectroscopic methods. Gallium 196-198 thioredoxin Homo sapiens 119-122 20384132-9 2010 The aforementioned experimental results will not only provide some guides to investigate the effects of fusion partner Trx on the unfolding thermodynamics, kinetics and refolding process of Trx-GcGASA, but also will be useful for further studies on the strucuture of GA-induced cysteine-rich protein with the help of spectroscopic methods. Gallium 196-198 thioredoxin Homo sapiens 190-193 20034680-2 2010 Here we show that GA treatment of mice with experimental autoimmune encephalomyelitis (EAE) biases cytokine production by B cells towards cytokines associated with regulation in MS including interleukin (IL)-4, -10 and -13 and reduces pro-inflammatory IL-6, IL-12, and TNF alpha levels. Gallium 18-20 interleukin 4 Mus musculus 191-222 20034680-2 2010 Here we show that GA treatment of mice with experimental autoimmune encephalomyelitis (EAE) biases cytokine production by B cells towards cytokines associated with regulation in MS including interleukin (IL)-4, -10 and -13 and reduces pro-inflammatory IL-6, IL-12, and TNF alpha levels. Gallium 18-20 interleukin 6 Mus musculus 252-256 20034680-2 2010 Here we show that GA treatment of mice with experimental autoimmune encephalomyelitis (EAE) biases cytokine production by B cells towards cytokines associated with regulation in MS including interleukin (IL)-4, -10 and -13 and reduces pro-inflammatory IL-6, IL-12, and TNF alpha levels. Gallium 18-20 tumor necrosis factor Mus musculus 269-278 20034680-3 2010 GA also down-regulates expression of B cell-activating factor (BAFF) of the TNF family and a proliferation-inducing ligand (APRIL), as well as the BAFF receptor in mice with EAE. Gallium 0-2 tumor necrosis factor (ligand) superfamily, member 13b Mus musculus 37-68 20034680-3 2010 GA also down-regulates expression of B cell-activating factor (BAFF) of the TNF family and a proliferation-inducing ligand (APRIL), as well as the BAFF receptor in mice with EAE. Gallium 0-2 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 91-122 20034680-3 2010 GA also down-regulates expression of B cell-activating factor (BAFF) of the TNF family and a proliferation-inducing ligand (APRIL), as well as the BAFF receptor in mice with EAE. Gallium 0-2 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 124-129 20034680-3 2010 GA also down-regulates expression of B cell-activating factor (BAFF) of the TNF family and a proliferation-inducing ligand (APRIL), as well as the BAFF receptor in mice with EAE. Gallium 0-2 tumor necrosis factor receptor superfamily, member 13c Mus musculus 147-160 19757159-9 2010 These results suggest that the expression of BnSLY1 was regulated by the exogenous GA3, ABA and PAC and may be related to endogenous level of GA in B. napus. Gallium 83-85 F-box protein GID2 Brassica napus 45-51 19936342-3 2009 Since the therapeutic response was unsatisfactory, a gallium-68 ((68)Ga)-Dotatoc-positron emission tomography (PET) was performed and demonstrated an enhanced SSTR 2 expression in the primary tumor but not in the liver metastases. Gallium 53-60 somatostatin receptor 2 Homo sapiens 159-165 20168287-0 2010 Biodistribution of the Ga-68 labeled somatostatin analogue DOTA-NOC in patients with neuroendocrine tumors: characterization of uptake in normal organs and tumor lesions. Gallium 23-25 nocturnin Homo sapiens 64-67 20641746-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 65-73 20641746-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 94-102 20641746-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 166-191 20641746-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 193-196 20641746-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide Homo sapiens 241-244 20641746-0 2004 (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Gallium 4-6 gastrin releasing peptide receptor Homo sapiens 256-260 20028185-11 2010 The model was found to be well-correlated (R = 0.9) with experimental oxime affinity for binding to GA-inhibited AChE. Gallium 100-102 acetylcholinesterase (Cartwright blood group) Homo sapiens 113-117 20028185-13 2010 These results provided the first predictive pharmacophore model of oxime affinity for binding toward GA-inhibited AChE. Gallium 101-103 acetylcholinesterase (Cartwright blood group) Homo sapiens 114-118 21832523-4 2009 Theoretically simulated STM images for Mn/GaAs(110) indicate round protrusions at As sites and Ga sites, the latter being dependent on the Mn adsorption site (i.e. in different atomic layers). Gallium 42-44 sulfotransferase family 1A member 3 Homo sapiens 24-27 19919057-0 2009 Gallium-67-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide for primary and metastatic melanoma imaging. Gallium 0-7 pro-opiomelanocortin-alpha Mus musculus 42-78 20021553-4 2009 Recent studies showed that GA modulates the expression of genes essential for JA biosynthesis to promote JA production and high levels of JA will induce the expression of three MYB genes MYB21, MYB24 and MYB57. Gallium 27-29 myb domain protein 21 Arabidopsis thaliana 187-192 20021553-4 2009 Recent studies showed that GA modulates the expression of genes essential for JA biosynthesis to promote JA production and high levels of JA will induce the expression of three MYB genes MYB21, MYB24 and MYB57. Gallium 27-29 myb domain protein 24 Arabidopsis thaliana 194-199 20021553-4 2009 Recent studies showed that GA modulates the expression of genes essential for JA biosynthesis to promote JA production and high levels of JA will induce the expression of three MYB genes MYB21, MYB24 and MYB57. Gallium 27-29 myb domain protein 57 Arabidopsis thaliana 204-209 20222429-14 2009 CONCLUSION: GA could inhibit the secondary inflamation of AA rats and decrease the level of TNF-alpha and IL-1beta protein in the AA rats serum. Gallium 12-14 tumor necrosis factor Rattus norvegicus 92-101 20222429-14 2009 CONCLUSION: GA could inhibit the secondary inflamation of AA rats and decrease the level of TNF-alpha and IL-1beta protein in the AA rats serum. Gallium 12-14 interleukin 1 beta Rattus norvegicus 106-114 20222429-15 2009 GA could inhibit the proliferation of AA rat synoviocytes in vitro and induce apoptosis which mechanism was concerned with down-regulating the mRNA expression of Bcl-2 and up-regulating that of Bax. Gallium 0-2 BCL2, apoptosis regulator Rattus norvegicus 162-167 20222429-15 2009 GA could inhibit the proliferation of AA rat synoviocytes in vitro and induce apoptosis which mechanism was concerned with down-regulating the mRNA expression of Bcl-2 and up-regulating that of Bax. Gallium 0-2 BCL2 associated X, apoptosis regulator Rattus norvegicus 194-197 32938150-4 2009 The limits of detection obtained for GA and ABA in leaf samples were 9.6 and 6.9 ng mL-1, respectively, which were in the concentration range (from hundreds to several ng g-1) for GA and ABA in leaves in different periods. Gallium 37-39 L1 cell adhesion molecule Mus musculus 84-88 32938150-4 2009 The limits of detection obtained for GA and ABA in leaf samples were 9.6 and 6.9 ng mL-1, respectively, which were in the concentration range (from hundreds to several ng g-1) for GA and ABA in leaves in different periods. Gallium 180-182 L1 cell adhesion molecule Mus musculus 84-88 20028185-5 2010 In an attempt to develop a rational strategy for the discovery and design of novel reactivators with lower toxicity and increased efficacy in reactivating GA-inhibited AChE, we developed the first in silico pharmacophore model for binding affinity of GA-inhibited AChE from a set of 11 oximes. Gallium 155-157 acetylcholinesterase (Cartwright blood group) Homo sapiens 168-172 20028185-5 2010 In an attempt to develop a rational strategy for the discovery and design of novel reactivators with lower toxicity and increased efficacy in reactivating GA-inhibited AChE, we developed the first in silico pharmacophore model for binding affinity of GA-inhibited AChE from a set of 11 oximes. Gallium 155-157 acetylcholinesterase (Cartwright blood group) Homo sapiens 264-268 20028185-7 2010 Quantum chemical methods were sequentially used from semiempirical AM1 to hierarchical ab initio calculations to determine the stereoelectronic properties of nine oximes exhibiting affinity for binding to GA-inhibited AChE in vivo. Gallium 205-207 acetylcholinesterase (Cartwright blood group) Homo sapiens 218-222 19939886-11 2010 By contrast, the loss-of-function erf1-2 mutant exhibited resistance to paclobutrazol, suggesting that eRF1-2 may exert a negative effect on the GA signalling pathway. Gallium 145-147 eukaryotic release factor 1-2 Arabidopsis thaliana 34-40 19939886-11 2010 By contrast, the loss-of-function erf1-2 mutant exhibited resistance to paclobutrazol, suggesting that eRF1-2 may exert a negative effect on the GA signalling pathway. Gallium 145-147 eukaryotic release factor 1-1 Arabidopsis thaliana 103-107 19874540-5 2010 Germination of dag1phyB seeds showed a reduced requirement of gibberellins as compared with phyB mutant seeds, both in the presence and in the absence of GA biosynthesis. Gallium 154-156 Dof-type zinc finger DNA-binding family protein Arabidopsis thaliana 15-19 19874540-8 2010 Our data indicate that in the phyB pathway leading to seed germination, DAG1 negatively regulates GA biosynthesis and suggest that DAG1 acts downstream of PIL5. Gallium 98-100 phytochrome B Arabidopsis thaliana 30-34 19874540-8 2010 Our data indicate that in the phyB pathway leading to seed germination, DAG1 negatively regulates GA biosynthesis and suggest that DAG1 acts downstream of PIL5. Gallium 98-100 Dof-type zinc finger DNA-binding family protein Arabidopsis thaliana 72-76 20011054-6 2010 GA administration also resulted in up-regulation of total PPARgamma and LPL expression levels in the visceral and subcutaneous adipose tissues, abdominal and quadriceps femoris muscles, as well as liver and kidney, with a significant up-regulation only in the visceral adipose tissue, abdominal and quadriceps femoris muscles. Gallium 0-2 peroxisome proliferator-activated receptor gamma Rattus norvegicus 58-67 20011054-6 2010 GA administration also resulted in up-regulation of total PPARgamma and LPL expression levels in the visceral and subcutaneous adipose tissues, abdominal and quadriceps femoris muscles, as well as liver and kidney, with a significant up-regulation only in the visceral adipose tissue, abdominal and quadriceps femoris muscles. Gallium 0-2 lipoprotein lipase Rattus norvegicus 72-75 19648230-10 2009 Genetic analysis showed that the cho1 mutation partially restored delayed seed germination and reduced GA biosynthesis activity in the ABA-overaccumulating cyp707a2-1 mutant background but did not restore seed germination in the GA-deficient ga1-3 mutant background. Gallium 103-105 AINTEGUMENTA-like 5 Arabidopsis thaliana 33-37 19360404-0 2009 (68)Ga-labeled NOTA-RGD-BBN peptide for dual integrin and GRPR-targeted tumor imaging. Gallium 4-6 gastrin releasing peptide Homo sapiens 24-27 19360404-0 2009 (68)Ga-labeled NOTA-RGD-BBN peptide for dual integrin and GRPR-targeted tumor imaging. Gallium 4-6 gastrin releasing peptide receptor Homo sapiens 58-62 19520291-0 2009 Development of high-specific-activity (68)Ga-labeled DOTA-rhenium-cyclized alpha-MSH peptide analog to target MC1 receptors overexpressed by melanoma tumors. Gallium 42-44 pro-opiomelanocortin-alpha Mus musculus 75-84 19687220-6 2009 Inflammatory disease has been imaged, even before the advent of PET, with planar and SPECT imaging using gallium-67, a radiometal that binds to transferrin. Gallium 105-112 transferrin Homo sapiens 144-155 19576768-6 2009 Moreover, by visualizing the cell cycle marker cyclinB1::beta-glucuronidase in GA-signaling mutants, we show that GA modulate cell cycle activity in the root meristem via a DELLA-dependent mechanism. Gallium 79-81 cyclin B1 Arabidopsis thaliana 47-55 19576768-6 2009 Moreover, by visualizing the cell cycle marker cyclinB1::beta-glucuronidase in GA-signaling mutants, we show that GA modulate cell cycle activity in the root meristem via a DELLA-dependent mechanism. Gallium 114-116 cyclin B1 Arabidopsis thaliana 47-55 19576770-5 2009 Targeting the expression of gai (a non-GA-degradable mutant form of GAI) in the root meristem disrupts cell proliferation. Gallium 39-41 GRAS family transcription factor family protein Arabidopsis thaliana 28-31 19576770-5 2009 Targeting the expression of gai (a non-GA-degradable mutant form of GAI) in the root meristem disrupts cell proliferation. Gallium 39-41 GRAS family transcription factor family protein Arabidopsis thaliana 68-71 19464431-0 2009 Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma. Gallium 18-20 heat shock protein 90 alpha family class A member 1 Rattus norvegicus 0-5 19493962-2 2009 Additionally, induction of AtCOX6b-1 by GA(3) and AtCOX6b-3 by 6-benzylaminopurine was observed. Gallium 40-42 cytochrome C oxidase 6B Arabidopsis thaliana 27-34 19277466-6 2009 Nonetheless, anti-NKp30 or anti-CD86 inhibited GA-enhanced human NK cell lysis of immature DCs. Gallium 47-49 natural cytotoxicity triggering receptor 3 Homo sapiens 18-23 19159928-0 2009 (68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin alphavbeta3 PET imaging. Gallium 4-6 integrin subunit alpha V Homo sapiens 88-108 19308988-2 2009 In control and GA-treated rat gliosarcoma cells, it has been reported that the translational efficiency of hsp90alpha is higher than hsp90beta. Gallium 15-17 heat shock protein 90 alpha family class B member 1 Rattus norvegicus 133-142 19228341-2 2009 Coordination of the two pathways involves the O-linked N-acetylglucosamine transferase SPINDLY (SPY) that suppresses GA signaling and promotes cytokinin responses in Arabidopsis. Gallium 117-119 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 87-94 19228341-2 2009 Coordination of the two pathways involves the O-linked N-acetylglucosamine transferase SPINDLY (SPY) that suppresses GA signaling and promotes cytokinin responses in Arabidopsis. Gallium 117-119 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 96-99 19228341-5 2009 Using chimeric GFP-SPY fused to a nuclear-export signal or to a glucocorticoid receptor, we show that cytosolic SPY promotes cytokinin responses and suppresses GA signaling. Gallium 160-162 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 112-115 19567707-7 2009 The KN1 binding site is conserved in ga2ox1 genes of different grasses, suggesting that the local regulation of bioactive GA levels through KNOX proteins is a common theme in grasses. Gallium 122-124 homeotic protein knotted-1 Zea mays 4-7 19470447-4 2009 From rat data, it is estimated that a 185-MBq injection of (67)Ga-diethylenetriaminepentaacetic acid-ACTH into a human might result in an estimated absorbed dose of 2.22 mGy to the whole body; the highest absorbed dose was in the bladder wall with 82.1 mGy and the organs that received the next highest doses were the lungs 31.8, liver 22.6 and spleen 8.72 mGy. Gallium 63-65 proopiomelanocortin Homo sapiens 101-105 19928283-7 2009 It is observed that Ga(3d) core level peak shifts during nitridation and N(1s) core level spectra shows that the intensity of the nitrogen peak increases and the Ga (LMM) auger peak shifts towards the higher binding energy, reveal the forming of N bonds with Ga by replacing the Ga-As bonds, forming GaN. Gallium 20-22 gigaxonin Homo sapiens 300-303 19221880-7 2009 StCDPK1 expression was induced by GA, ABA and BAP. Gallium 34-36 calcium-dependent protein kinase Solanum tuberosum 0-7 19296634-5 2009 The optimizations at the MP2 level distorted the D(2h) C(2)E(4) (E = Ga, In, and Tl) slightly and the distortion energies are less than 0.02 kcal/mol. Gallium 69-71 tryptase pseudogene 1 Homo sapiens 25-28 19296634-6 2009 The C(2)E(4) (E = Al, Ga, In, and Tl) with dptCs are 18.0, 18.3, 13.4, and 12.2 kcal/mol energetically more favorable than their nearest isomers, respectively, at the CCSD(T)//MP2 level with aug-cc-pVTZ for C and Al and aug-cc-pVTZ-PP for Ga, In, and Tl basis set. Gallium 22-24 tryptase pseudogene 1 Homo sapiens 176-179 19277466-6 2009 Nonetheless, anti-NKp30 or anti-CD86 inhibited GA-enhanced human NK cell lysis of immature DCs. Gallium 47-49 CD86 molecule Homo sapiens 32-36 19277466-8 2009 Further, GA inhibited the release of IFN-gamma 24 h but increased the release of TNF-alpha 48 h after incubation with NK cells. Gallium 9-11 interferon gamma Homo sapiens 37-46 19242338-6 2009 Septic patients had greater pulmonary capillary permeability, edema, and severity of lung injury than nonseptic patients (p < 0.01), as measured by the pulmonary leak index (PLI) for Gallium-labeled transferrin, extravascular lung water (EVLW), and lung injury score (LIS), respectively. Gallium 186-193 transferrin Homo sapiens 202-213 19277466-8 2009 Further, GA inhibited the release of IFN-gamma 24 h but increased the release of TNF-alpha 48 h after incubation with NK cells. Gallium 9-11 tumor necrosis factor Homo sapiens 81-90 19121107-4 2009 Nod factor-induced root hair deformation was severely blocked in the presence of GA, which was phenocopied by nsp2 mutants. Gallium 81-83 Protein NODULATION SIGNALING PATHWAY 2 Lotus japonicus 110-114 19121107-7 2009 Nod factor-dependent induction of NSP2 and NIN was inhibited by exogenous GA. Gallium 74-76 Protein NODULATION SIGNALING PATHWAY 2 Lotus japonicus 34-38 19121107-8 2009 Furthermore, the cytokinin-dependent induction of NIN was suppressed by GA. From these results, we conclude that GA inhibits the nodulation signaling pathway downstream of cytokinin, possibly at NSP2, which is required for Nod factor-dependent NIN expression. Gallium 72-74 Protein NODULATION SIGNALING PATHWAY 2 Lotus japonicus 195-199 19106376-8 2008 Overexpression of CDPK1 inhibited the feedback regulation of a GA 20-oxidase gene and resulted in sensitization to the GA biosynthetic inhibitor. Gallium 63-65 calcium-dependent protein kinase 21-like Nicotiana tabacum 18-23 19325888-9 2009 Further genetic and molecular studies demonstrate that GA suppresses DELLAs to mobilize the expression of the key JA biosynthesis gene DAD1, and this is consistent with the observation that the JA content in the young flower buds of the GA-deficient quadruple mutant ga1-3 gai-t6 rga-t2 rgl1-1 is much lower than that in the WT. Gallium 55-57 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 135-139 19325888-9 2009 Further genetic and molecular studies demonstrate that GA suppresses DELLAs to mobilize the expression of the key JA biosynthesis gene DAD1, and this is consistent with the observation that the JA content in the young flower buds of the GA-deficient quadruple mutant ga1-3 gai-t6 rga-t2 rgl1-1 is much lower than that in the WT. Gallium 55-57 GRAS family transcription factor family protein Arabidopsis thaliana 280-283 19325888-9 2009 Further genetic and molecular studies demonstrate that GA suppresses DELLAs to mobilize the expression of the key JA biosynthesis gene DAD1, and this is consistent with the observation that the JA content in the young flower buds of the GA-deficient quadruple mutant ga1-3 gai-t6 rga-t2 rgl1-1 is much lower than that in the WT. Gallium 55-57 RGA-like 1 Arabidopsis thaliana 287-291 19325888-10 2009 We conclude that GA promotes JA biosynthesis to control the expression of MYB21, MYB24, and MYB57. Gallium 17-19 myb domain protein 21 Arabidopsis thaliana 74-79 19325888-10 2009 We conclude that GA promotes JA biosynthesis to control the expression of MYB21, MYB24, and MYB57. Gallium 17-19 myb domain protein 24 Arabidopsis thaliana 81-86 19325888-10 2009 We conclude that GA promotes JA biosynthesis to control the expression of MYB21, MYB24, and MYB57. Gallium 17-19 myb domain protein 57 Arabidopsis thaliana 92-97 19704711-1 2009 We recently reported that the DELLA factor RGL2 represses testa rupture in response to changes in ABA and GA levels. Gallium 106-108 ral guanine nucleotide dissociation stimulator like 2 Homo sapiens 43-47 18643985-9 2008 These results demonstrate that, under salinity stress, Arabidopsis plants actively reduce endogenous GA levels via the induction of GA 2-oxidase, with the result that growth is repressed for stress adaptation. Gallium 101-103 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 132-136 18446369-6 2008 The results of immunohistochemistry confirmed that transgelin was indeed over-expressed in 22 cases of GA (22/41, 53.66%), with strong cytoplasmic staining in cancer cells of positive samples, this was absent in most paired non-neoplastic mucosa cells or gastric ulcer tissues (n = 20). Gallium 103-105 transgelin Homo sapiens 51-61 18586083-6 2008 N-Acetyl-L-cysteine blocked gallium-induced MT2A and HO-1 expression and increased gallium"s cytotoxicity. Gallium 28-35 metallothionein 2A Homo sapiens 44-48 18080306-5 2008 GA was incorporated into the polymer chain to prevent crystallization of PCL component and increase the polymer degradation. Gallium 0-2 PHD finger protein 1 Homo sapiens 73-76 18586083-2 2008 Using a DNA microarray to examine genes induced by gallium nitrate in CCRF-CEM cells, we found that gallium increased metallothionein-2A (MT2A) and heme oxygenase-1 (HO-1) gene expression and altered the levels of other stress-related genes. Gallium 51-58 metallothionein 2A Homo sapiens 118-136 18586083-2 2008 Using a DNA microarray to examine genes induced by gallium nitrate in CCRF-CEM cells, we found that gallium increased metallothionein-2A (MT2A) and heme oxygenase-1 (HO-1) gene expression and altered the levels of other stress-related genes. Gallium 51-58 metallothionein 2A Homo sapiens 138-142 18586083-2 2008 Using a DNA microarray to examine genes induced by gallium nitrate in CCRF-CEM cells, we found that gallium increased metallothionein-2A (MT2A) and heme oxygenase-1 (HO-1) gene expression and altered the levels of other stress-related genes. Gallium 51-58 heme oxygenase 1 Homo sapiens 148-164 18586083-2 2008 Using a DNA microarray to examine genes induced by gallium nitrate in CCRF-CEM cells, we found that gallium increased metallothionein-2A (MT2A) and heme oxygenase-1 (HO-1) gene expression and altered the levels of other stress-related genes. Gallium 51-58 heme oxygenase 1 Homo sapiens 166-170 18827182-5 2008 The sly1 mutants accumulate more DELLA proteins but display less severe dwarf and germination phenotypes than the GA biosynthesis mutant ga1-3 or the gid1abc triple mutant. Gallium 114-116 F-box family protein Arabidopsis thaliana 4-8 18630902-2 2008 Accordingly, the insertion of Ga(DDP) into the Ga-Me bond of GaMe 3 yield in the complexes [{(DDP)GaMe}GaMe 2] ( 1) and [{(DDP)GaMe} 2GaMe] ( 2), respectively, which show a temperature-dependent equilibrium between 1 at higher temperatures and 2 at lower temperatures. Gallium 30-32 translocase of inner mitochondrial membrane 8A Homo sapiens 33-36 18630902-2 2008 Accordingly, the insertion of Ga(DDP) into the Ga-Me bond of GaMe 3 yield in the complexes [{(DDP)GaMe}GaMe 2] ( 1) and [{(DDP)GaMe} 2GaMe] ( 2), respectively, which show a temperature-dependent equilibrium between 1 at higher temperatures and 2 at lower temperatures. Gallium 30-32 translocase of inner mitochondrial membrane 8A Homo sapiens 94-97 18757556-5 2008 We show that cold/CBF1 enhances the accumulation of a green fluorescent protein (GFP)-tagged DELLA protein (GFP-RGA) by reducing GA content through stimulating expression of GA-inactivating GA 2-oxidase genes. Gallium 113-115 recombination signal binding protein for immunoglobulin kappa J region Homo sapiens 18-22 18757556-5 2008 We show that cold/CBF1 enhances the accumulation of a green fluorescent protein (GFP)-tagged DELLA protein (GFP-RGA) by reducing GA content through stimulating expression of GA-inactivating GA 2-oxidase genes. Gallium 129-131 recombination signal binding protein for immunoglobulin kappa J region Homo sapiens 18-22 18757556-7 2008 Both phenotypes are suppressed when CBF1 is expressed in a line lacking two DELLA proteins, GA-INSENSITIVE and REPRESSOR OF GA1-3. Gallium 92-94 recombination signal binding protein for immunoglobulin kappa J region Homo sapiens 36-40 18586083-6 2008 N-Acetyl-L-cysteine blocked gallium-induced MT2A and HO-1 expression and increased gallium"s cytotoxicity. Gallium 28-35 heme oxygenase 1 Homo sapiens 53-57 18586083-9 2008 Gallium-induced Nrf-2 activation and HO-1 expression were diminished by a p38 MAP kinase inhibitor. Gallium 0-7 NFE2 like bZIP transcription factor 2 Homo sapiens 16-21 18586083-9 2008 Gallium-induced Nrf-2 activation and HO-1 expression were diminished by a p38 MAP kinase inhibitor. Gallium 0-7 heme oxygenase 1 Homo sapiens 37-41 20641543-0 2004 (64)Cu-[cinnamoyl-Phe-D-Leu-Phe-D-Leu-Phe-Lys(PEG-1,4,7,10-Tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid)-NH2] White blood cells radiolabeled with indium (as (111)In-hexamethylpropyleneamine oxime), technetium (as (99m)Tc-stannous chloride), or gallium (as (67)Ga-citrate) are often used for the detection of infection and inflammation (1). Gallium 252-259 mesoderm specific transcript Homo sapiens 46-51 18285551-6 2008 Similarly, for the m301G>A>T, major allele carriers displayed maximal reduction of CRP over noncarriers (-20 for GG, -15 for GA and GT, and -0.3% for TA and AA; P = 0.020). Gallium 131-133 C-reactive protein Homo sapiens 89-92 18025811-7 2008 For imaging experiments, the SSTR ligands (68)Ga-DOTATOC or (68)Ga-DOTANOC were injected intravenously, and animals were subsequently examined in an animal positron emission tomography scanner and a clinical 3T (tesla) magnetic resonance imager. Gallium 46-48 somatostatin receptor 3 Rattus norvegicus 29-33 18180041-1 2008 The interactions of transferrin (Tf) with the water soluble corrole 1 and with its gallium (1-Ga) and manganese (1-Mn) complexes were studied to establish the possible utilization of corrole-transferrin conjugates for targeting these corroles to cells that express the transferrin receptor. Gallium 83-90 transferrin Homo sapiens 20-31 18180041-1 2008 The interactions of transferrin (Tf) with the water soluble corrole 1 and with its gallium (1-Ga) and manganese (1-Mn) complexes were studied to establish the possible utilization of corrole-transferrin conjugates for targeting these corroles to cells that express the transferrin receptor. Gallium 83-90 transferrin Homo sapiens 33-35 19825541-10 2008 Additionally, a 2-oxidase inhibitor (Trinexapac Ethyl) enhanced the activity of applied GA(4), as did limiting C-16,17 epoxidation in 16,17-dihydro GAs or after C-13 hydroxylation. Gallium 88-90 homeobox C13 Homo sapiens 161-165 19825541-11 2008 Overall, deactivation of GA(1) and GA(4) just below the shoot apex effectively restricts their florigenicity in Lolium and, conversely, with GA(5), C-2 and C-13 protection against deactivation allows its high florigenicity. Gallium 25-27 complement C2 Homo sapiens 148-151 19825541-11 2008 Overall, deactivation of GA(1) and GA(4) just below the shoot apex effectively restricts their florigenicity in Lolium and, conversely, with GA(5), C-2 and C-13 protection against deactivation allows its high florigenicity. Gallium 25-27 homeobox C13 Homo sapiens 156-160 19825541-11 2008 Overall, deactivation of GA(1) and GA(4) just below the shoot apex effectively restricts their florigenicity in Lolium and, conversely, with GA(5), C-2 and C-13 protection against deactivation allows its high florigenicity. Gallium 35-37 homeobox C13 Homo sapiens 156-160 19825541-11 2008 Overall, deactivation of GA(1) and GA(4) just below the shoot apex effectively restricts their florigenicity in Lolium and, conversely, with GA(5), C-2 and C-13 protection against deactivation allows its high florigenicity. Gallium 35-37 homeobox C13 Homo sapiens 156-160 18069939-7 2008 The ga20ox2 phenotype revealed that GA promotes the number of stem internodes that elongate upon bolting, and does so independently of its effect on internode elongation. Gallium 36-38 gibberellin 20 oxidase 2 Arabidopsis thaliana 4-11 18411850-4 2008 The structures of M(Bu(t))3 (M = Al, Ga, In) have been calculated ab initio and those for the aluminium and gallium derivatives are in good agreement with the electron-diffraction structures. Gallium 37-39 solute carrier family 25 member 5 Homo sapiens 18-27 18411850-4 2008 The structures of M(Bu(t))3 (M = Al, Ga, In) have been calculated ab initio and those for the aluminium and gallium derivatives are in good agreement with the electron-diffraction structures. Gallium 108-115 solute carrier family 25 member 5 Homo sapiens 18-27 17964545-4 2007 The variant frequency of GSTP1 among the present subjects (n=210) was AA 71.0%; GA 27.0% and GG 1.9%. Gallium 80-82 glutathione S-transferase pi 1 Homo sapiens 25-30 17944527-2 2007 Earlier investigations showed successful imaging of HER2-positive tumors in patients using indium- or gallium-labeled Affibody molecules. Gallium 102-109 erb-b2 receptor tyrosine kinase 2 Homo sapiens 52-56 17963786-7 2007 Moreover, the simultaneous addition of GA and dihydrokainate (DHK), a specific inhibitor of GLT1, resulted in a significantly higher inhibition of [(3)H]glutamate uptake by cortical slices of 7-day-old rats than that induced by the sole presence of DHK. Gallium 39-41 solute carrier family 1 member 2 Rattus norvegicus 92-96 17617464-6 2007 Compared with an LC(50) (the half-maximal cytotoxic concentration) value of 1.93 microM in drug-sensitive (Pgp-) cells, the gallium(III) complex 5 demonstrated an LC(50) value>100 microM in drug-resistant (Pgp+) cells, thus indicating that 5 was recognized by the Pgp as its substrate, thereby extruded from the cells and sequestered away from their cytotoxic targets. Gallium 124-131 ATP binding cassette subfamily B member 1 Homo sapiens 107-110 17643429-6 2007 We observed that Akt was degraded more rapidly in the presence of GA than upon translation inhibition without NPM-ALK expression. Gallium 66-68 AKT serine/threonine kinase 1 Homo sapiens 17-20 17617464-6 2007 Compared with an LC(50) (the half-maximal cytotoxic concentration) value of 1.93 microM in drug-sensitive (Pgp-) cells, the gallium(III) complex 5 demonstrated an LC(50) value>100 microM in drug-resistant (Pgp+) cells, thus indicating that 5 was recognized by the Pgp as its substrate, thereby extruded from the cells and sequestered away from their cytotoxic targets. Gallium 124-131 ATP binding cassette subfamily B member 1 Homo sapiens 209-212 17617464-6 2007 Compared with an LC(50) (the half-maximal cytotoxic concentration) value of 1.93 microM in drug-sensitive (Pgp-) cells, the gallium(III) complex 5 demonstrated an LC(50) value>100 microM in drug-resistant (Pgp+) cells, thus indicating that 5 was recognized by the Pgp as its substrate, thereby extruded from the cells and sequestered away from their cytotoxic targets. Gallium 124-131 ATP binding cassette subfamily B member 1 Homo sapiens 209-212 17600139-5 2007 The role of the transferrin receptor (TfR) in gallium maltolate"s action was examined using monoclonal antibody (MoAb) 42/6 to block TfR function. Gallium 46-53 transferrin receptor Homo sapiens 16-36 17998097-0 2007 Gallium-68-labeled DOTA-rhenium-cyclized alpha-melanocyte-stimulating hormone analog for imaging of malignant melanoma. Gallium 0-7 proopiomelanocortin Homo sapiens 41-77 17600139-5 2007 The role of the transferrin receptor (TfR) in gallium maltolate"s action was examined using monoclonal antibody (MoAb) 42/6 to block TfR function. Gallium 46-53 transferrin receptor Homo sapiens 38-41 17600139-10 2007 Gallium maltolate is incorporated into lymphoma cells to a greater extent than gallium nitrate via both TfR-independent and -dependent pathways; it has significant activity against gallium nitrate-resistant cells and acts independently of p53. Gallium 0-7 transferrin receptor Homo sapiens 104-107 17503074-8 2007 As genes involved in the control of GA synthesis (LeT6, LeT12 and LeCUC2) and response (SPY) are also altered in the pat ovary, it is suggested that the pat mutation affects a regulatory gene located upstream of the control of fruit set exerted by GAs. Gallium 36-38 homeobox protein knotted-1-like LET12 Solanum lycopersicum 56-61 17503074-8 2007 As genes involved in the control of GA synthesis (LeT6, LeT12 and LeCUC2) and response (SPY) are also altered in the pat ovary, it is suggested that the pat mutation affects a regulatory gene located upstream of the control of fruit set exerted by GAs. Gallium 36-38 probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Solanum lycopersicum 88-91 17884779-5 2007 Administration of organic gallium and gallium chloride treatments increased the bone density, bone cortex thickness and the percentage of bone trabecula, and Ga, Ca, P contents in the femur and teeth, but lowered the activity of TRAP and AKP, suggesting decreased bone conversion rate. Gallium 26-33 acid phosphatase 5, tartrate resistant Rattus norvegicus 229-233 17644628-4 2007 Although scc7-D is hypersensitive to light, transgenic seedlings expressing GA2ox at a level higher than scc7-D showed a constitutive photomorphogenic phenotype, confirming a general role of GA2ox and GA in the suppression of hypocotyl elongation. Gallium 76-78 electron transfer flavoprotein subunit alpha Homo sapiens 191-194 20641498-15 2004 For this, a gallium ((68)Ga)-labeled F(ab ) fragment of trastuzumab, which is a commercially available antibody against EGFR, was used to determine the alterations of HER2 expression in response to 17-AAG (3). Gallium 12-19 epidermal growth factor receptor Homo sapiens 120-124 17333251-6 2007 Mutation of eight conserved Tyr residues of RGL2 into alanine shows four mutant proteins (Y52A, Y89A, Y223A and Y435A) are resistant to GA-induced degradation. Gallium 136-138 RGA-like 2 Arabidopsis thaliana 44-48 17333251-8 2007 However, further mutation of these four Tyrs into conservative phenylalanine (Y --> F) rendered the mutant proteins sensitive to GA like the wild-type RGL2. Gallium 132-134 RGA-like 2 Arabidopsis thaliana 154-158 20641498-15 2004 For this, a gallium ((68)Ga)-labeled F(ab ) fragment of trastuzumab, which is a commercially available antibody against EGFR, was used to determine the alterations of HER2 expression in response to 17-AAG (3). Gallium 12-19 erb-b2 receptor tyrosine kinase 2 Homo sapiens 167-171 17461792-9 2007 Chromatin immunoprecipitation results indicated that AtGA20ox1, a gene encoding the key enzyme in GA biosynthesis, is a target gene regulated by AtOFP1. Gallium 55-57 ovate family protein 1 Arabidopsis thaliana 145-151 17547397-4 2007 The experimental results are discussed in comparison with molecular dynamic calculations to assess the presence of covalent character of the dimeric Ga2 units in liquid nanostructured gallium. Gallium 184-191 electron transfer flavoprotein subunit alpha Homo sapiens 149-152 17514342-0 2007 Structural diversity in gallium(III) complexes of the tripodal triarsine MeC(CH2AsMe2)3. Gallium 24-31 C-C motif chemokine ligand 28 Homo sapiens 73-76 17486124-6 2007 Addition of exogenous GA(3) could partially rescue the dwarf phenotype, suggesting that the dwarf phenotype of the pds3 mutant might be due to GA deficiency. Gallium 22-24 phytoene desaturase 3 Arabidopsis thaliana 115-119 17556810-3 2007 Results of semi-quantitative reverse transcription PCR (RT-PCR) analysis indicated that AtCPK30 was highly expressed in root and induced by ABA, IAA, 2,4-D, GA(3) and 6-BA treatment. Gallium 157-159 calcium-dependent protein kinase 30 Arabidopsis thaliana 88-95 17486124-7 2007 Microarray and RT-PCR analysis showed that disrupting PDS3 gene resulted in gene expression changes involved in at least 20 metabolic pathways, including the inhibition of many genes in carotenoid, chlorophyll, and GA biosynthesis pathways. Gallium 215-217 phytoene desaturase 3 Arabidopsis thaliana 54-58 17322332-4 2007 Expression of the key GA biosynthetic genes GA3ox1 and 2 was greatly reduced in cts seeds and genetic analysis suggested that CTS was epistatic to RGL2, a germination-repressing DELLA protein that is degraded by GA. Gallium 22-24 gibberellin 3-oxidase 1 Arabidopsis thaliana 44-56 17322332-4 2007 Expression of the key GA biosynthetic genes GA3ox1 and 2 was greatly reduced in cts seeds and genetic analysis suggested that CTS was epistatic to RGL2, a germination-repressing DELLA protein that is degraded by GA. Gallium 22-24 peroxisomal ABC transporter 1 Arabidopsis thaliana 80-83 17322332-4 2007 Expression of the key GA biosynthetic genes GA3ox1 and 2 was greatly reduced in cts seeds and genetic analysis suggested that CTS was epistatic to RGL2, a germination-repressing DELLA protein that is degraded by GA. Gallium 22-24 peroxisomal ABC transporter 1 Arabidopsis thaliana 126-129 17322332-4 2007 Expression of the key GA biosynthetic genes GA3ox1 and 2 was greatly reduced in cts seeds and genetic analysis suggested that CTS was epistatic to RGL2, a germination-repressing DELLA protein that is degraded by GA. Gallium 22-24 RGA-like 2 Arabidopsis thaliana 147-151 17383526-10 2007 GA caused a specific early upregulation of TNF-alpha mRNA expression and intracellular TNF-alpha synthesis. Gallium 0-2 tumor necrosis factor Mus musculus 43-52 17383526-10 2007 GA caused a specific early upregulation of TNF-alpha mRNA expression and intracellular TNF-alpha synthesis. Gallium 0-2 tumor necrosis factor Mus musculus 87-96 17383526-11 2007 The GA and THD groups showed early serum IL-2 production with reduction of IL-10 mRNA expression and intracellular IL-10 synthesis in the early post-operative phase. Gallium 4-6 interleukin 2 Mus musculus 41-45 17383526-11 2007 The GA and THD groups showed early serum IL-2 production with reduction of IL-10 mRNA expression and intracellular IL-10 synthesis in the early post-operative phase. Gallium 4-6 interleukin 10 Mus musculus 75-80 17383526-11 2007 The GA and THD groups showed early serum IL-2 production with reduction of IL-10 mRNA expression and intracellular IL-10 synthesis in the early post-operative phase. Gallium 4-6 interleukin 10 Mus musculus 115-120 17006669-5 2007 The mutant phenotype prompted the hypothesis that AMP1 is involved in ethylene and GA signalling pathways or in a parallel pathway-controlling cell and hypocotyl elongation and cellular organization. Gallium 83-85 Peptidase M28 family protein Arabidopsis thaliana 50-54 17277098-6 2007 We have identified a cis-acting sequence responsible for the GA-negative feedback of AtGA3ox1 using transgenic plants. Gallium 61-63 gibberellin 3-oxidase 1 Arabidopsis thaliana 85-93 17277098-10 2007 Our results suggest that AGF1 plays a role in the homeostasis of GAs through binding to the cis-acting sequence of the GA-negative feedback of AtGA3ox1. Gallium 65-67 AT-hook protein of GA feedback 1 Arabidopsis thaliana 25-29 17277098-10 2007 Our results suggest that AGF1 plays a role in the homeostasis of GAs through binding to the cis-acting sequence of the GA-negative feedback of AtGA3ox1. Gallium 65-67 gibberellin 3-oxidase 1 Arabidopsis thaliana 143-151 17384169-4 2007 Unlike ga1-3, the GA-insensitive sly1 mutants show variable seed dormancy. Gallium 18-20 F-box family protein Arabidopsis thaliana 33-37 17384169-8 2007 Without GA, several GA-induced genes show increased accumulation in sly1 seeds compared with ga1-3. Gallium 20-22 F-box family protein Arabidopsis thaliana 68-72 16868182-5 2007 In analyzing the function of Hsp90 regarding the cytotoxicity/viability of macrophages, we found that the combination of LPS and GA increases apoptosis, as evidenced by the increased caspase-3 activity and the proportion of nuclear/chromatin condensation. Gallium 129-131 heat shock protein 90 alpha family class A member 1 Homo sapiens 29-34 17268055-1 2007 We have recently reported that transferrin (Tf)-unbound gallium-67 (67Ga) may be taken up into the liver of carbon tetrachloride (CCl4)-treated rats. Gallium 56-63 transferrin Rattus norvegicus 31-42 17268055-1 2007 We have recently reported that transferrin (Tf)-unbound gallium-67 (67Ga) may be taken up into the liver of carbon tetrachloride (CCl4)-treated rats. Gallium 56-63 C-C motif chemokine ligand 4 Rattus norvegicus 130-134 17308060-5 2007 Gallium-resistant cells were found to display a marked increase in gene expression for metallothionein-2A and the zinc transporter ZnT-1. Gallium 0-7 metallothionein 2A Homo sapiens 87-105 17308060-5 2007 Gallium-resistant cells were found to display a marked increase in gene expression for metallothionein-2A and the zinc transporter ZnT-1. Gallium 0-7 solute carrier family 30 member 1 Homo sapiens 131-136 17308060-10 2007 Our studies show for the first time that gallium acts on pathways related to zinc metabolism and that metal-responsive transcription factor-1 activity and metallothionein expression contribute to the development of gallium drug resistance. Gallium 215-222 metal regulatory transcription factor 1 Homo sapiens 102-141 17142481-10 2007 The DELLA motif in RGA is essential for GA-induced proteolysis of RGA, and deletion of this motif (as in rga-delta17) causes a GA-insensitive dwarf phenotype. Gallium 20-22 GRAS family transcription factor family protein Arabidopsis thaliana 66-69 17142481-10 2007 The DELLA motif in RGA is essential for GA-induced proteolysis of RGA, and deletion of this motif (as in rga-delta17) causes a GA-insensitive dwarf phenotype. Gallium 20-22 GRAS family transcription factor family protein Arabidopsis thaliana 105-108 17142481-10 2007 The DELLA motif in RGA is essential for GA-induced proteolysis of RGA, and deletion of this motif (as in rga-delta17) causes a GA-insensitive dwarf phenotype. Gallium 40-42 GRAS family transcription factor family protein Arabidopsis thaliana 19-22 17142481-10 2007 The DELLA motif in RGA is essential for GA-induced proteolysis of RGA, and deletion of this motif (as in rga-delta17) causes a GA-insensitive dwarf phenotype. Gallium 40-42 GRAS family transcription factor family protein Arabidopsis thaliana 66-69 17142481-10 2007 The DELLA motif in RGA is essential for GA-induced proteolysis of RGA, and deletion of this motif (as in rga-delta17) causes a GA-insensitive dwarf phenotype. Gallium 40-42 GRAS family transcription factor family protein Arabidopsis thaliana 105-108 19071278-1 2007 A poly(vinyl alcohol) film cross-linked with glutaraldehyde (PVA-GA) was introduced to the surface of a tyrosinase-based carbon paste electrode. Gallium 65-67 tyrosinase Homo sapiens 104-114 17352436-2 2007 Their structures and the influence of their ligands (phosphorus and nitrogen atoms directly bonded to the Ga(8) moieties) are discussed on the basis of DFT calculations, providing an insight into a probable mechanism for insertion reactions between GaX and GaX(3) species that lead to a reaction cascade via halides like Ga(2)X(4) and Ga(5)X(7) to Ga(8)X(10) and Ga(8)X(12) (2-), respectively. Gallium 106-108 mesenchyme homeobox 2 Homo sapiens 249-252 17352436-2 2007 Their structures and the influence of their ligands (phosphorus and nitrogen atoms directly bonded to the Ga(8) moieties) are discussed on the basis of DFT calculations, providing an insight into a probable mechanism for insertion reactions between GaX and GaX(3) species that lead to a reaction cascade via halides like Ga(2)X(4) and Ga(5)X(7) to Ga(8)X(10) and Ga(8)X(12) (2-), respectively. Gallium 106-108 mesenchyme homeobox 2 Homo sapiens 257-260 16868182-5 2007 In analyzing the function of Hsp90 regarding the cytotoxicity/viability of macrophages, we found that the combination of LPS and GA increases apoptosis, as evidenced by the increased caspase-3 activity and the proportion of nuclear/chromatin condensation. Gallium 129-131 caspase 3 Homo sapiens 183-192 16868182-8 2007 Furthermore, we established the mechanism of GA interference with Hsp90 function for LPS-stimulated macrophages, resulting in increased ROS production and caspase-3 activation, and consequently leading to synergistic enhancement of macrophage apoptosis. Gallium 45-47 heat shock protein 90 alpha family class A member 1 Homo sapiens 66-71 16868182-8 2007 Furthermore, we established the mechanism of GA interference with Hsp90 function for LPS-stimulated macrophages, resulting in increased ROS production and caspase-3 activation, and consequently leading to synergistic enhancement of macrophage apoptosis. Gallium 45-47 caspase 3 Homo sapiens 155-164 17121930-12 2006 Our results suggest that TfR function rather than TfR number is important in gallium targeting to cells and that apoptosis is triggered by gallium through the mitochondrial pathway by activating proapoptotic Bax. Gallium 77-84 transferrin receptor Homo sapiens 25-28 17194763-3 2006 The triple mutant displayed a dwarf phenotype more severe than that of the extreme GA-deficient mutant ga1-3. Gallium 83-85 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 103-108 17308060-0 2007 Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. Gallium 28-35 solute carrier family 30 member 1 Homo sapiens 167-185 17308060-0 2007 Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. Gallium 50-57 metal regulatory transcription factor 1 Homo sapiens 102-141 17308060-0 2007 Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. Gallium 50-57 metallothionein 2A Homo sapiens 143-161 17308060-0 2007 Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. Gallium 50-57 solute carrier family 30 member 1 Homo sapiens 167-185 17121930-0 2006 Gallium-induced cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition. Gallium 0-7 transferrin receptor Homo sapiens 48-68 17121930-0 2006 Gallium-induced cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition. Gallium 0-7 BCL2 associated X, apoptosis regulator Homo sapiens 93-96 17121930-12 2006 Our results suggest that TfR function rather than TfR number is important in gallium targeting to cells and that apoptosis is triggered by gallium through the mitochondrial pathway by activating proapoptotic Bax. Gallium 139-146 BCL2 associated X, apoptosis regulator Homo sapiens 208-211 16740147-8 2006 Consistent with these gene-expression patterns, the amount of bioactive GA was higher in the pil5 mutant and lower in the PIL5 overexpression line. Gallium 72-74 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 93-97 16970376-1 2006 An ab initio computational study of the properties of the neutral AH2 radicals (A = B, Al, Ga) as hydrogen-bond (HB) acceptors, with H-X (X = F, Cl, Br, CN, and CCH) as HB donors, is carried out at the UMP2/6-311++G(2d,2p) level. Gallium 91-93 zinc finger RANBP2-type containing 3 Homo sapiens 66-69 16718728-1 2006 The topology of many modifications of elemental gallium is reflected in the large variety of metalloid Ga clusters that have been isolated as intermediates on the way from the metastable molecular GaX species (X=Cl, Br, I) by means of disproportionation to the bulk metal. Gallium 48-55 mesenchyme homeobox 2 Homo sapiens 197-200 16819174-1 2006 We have reported that transferrin (Tf)-unbound Gallium-67 ((67)Ga) was taken up into hepatocytes 1 d after carbon tetrachloride (CCl(4))-treatment in rats. Gallium 47-54 transferrin Rattus norvegicus 22-33 16819174-1 2006 We have reported that transferrin (Tf)-unbound Gallium-67 ((67)Ga) was taken up into hepatocytes 1 d after carbon tetrachloride (CCl(4))-treatment in rats. Gallium 47-54 transferrin Rattus norvegicus 35-37 16938349-7 2006 This implies that transferrin would rather mediate the accumulation of gallium antineoplastic agents in solid tumors. Gallium 71-78 transferrin Homo sapiens 18-29 17010113-6 2006 In addition, the ability to synthesize GA was improved in the aba2-2 mutant compared with wild type during dark-imbibition after an FR light pulse. Gallium 39-41 NAD(P)-binding Rossmann-fold superfamily protein Arabidopsis thaliana 62-66 17010113-7 2006 Activation of GA biosynthesis in the aba2-2 mutant was also observed during seed development. Gallium 14-16 NAD(P)-binding Rossmann-fold superfamily protein Arabidopsis thaliana 37-41 16815957-4 2006 A detailed dissection of ChrC promoter revealed a GA-responsive element, gacCTCcaa, the mutation of which abolished ChrC activation by GA. Gallium 50-52 plastid lipid associated protein CHRC Solanum lycopersicum 25-29 16815957-4 2006 A detailed dissection of ChrC promoter revealed a GA-responsive element, gacCTCcaa, the mutation of which abolished ChrC activation by GA. Gallium 50-52 plastid lipid associated protein CHRC Solanum lycopersicum 116-120 16815957-5 2006 This cis-element is different from the GARE motif and is involved in ChrC activation probably via negative regulation, similar to other GA-responsive systems. Gallium 39-41 plastid lipid associated protein CHRC Solanum lycopersicum 69-73 16740147-8 2006 Consistent with these gene-expression patterns, the amount of bioactive GA was higher in the pil5 mutant and lower in the PIL5 overexpression line. Gallium 72-74 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 122-126 16740147-9 2006 Lastly, we showed that red and far-red light signals trigger PIL5 protein degradation through the 26S proteasome, thus releasing the inhibition of bioactive GA biosynthesis by PIL5. Gallium 157-159 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 61-65 16740147-9 2006 Lastly, we showed that red and far-red light signals trigger PIL5 protein degradation through the 26S proteasome, thus releasing the inhibition of bioactive GA biosynthesis by PIL5. Gallium 157-159 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 176-180 16740147-10 2006 Taken together, our data indicate that phytochromes promote seed germination by degrading PIL5, which leads to increased GA biosynthesis and decreased GA degradation. Gallium 121-123 phytochrome interacting factor 3-like 5 Arabidopsis thaliana 90-94 16987073-6 2006 The number of thrombocytes was significantly lower in patients with the GA-238 genotype (low TNF-alpha producers) compared with patients with the GG-238 genotype. Gallium 72-74 tumor necrosis factor Homo sapiens 93-102 16679458-6 2006 Genetic and gene expression analyses suggest that GIS acts in a GA-responsive pathway upstream of the trichome initiation regulator GLABROUS1 (GL1) and downstream of the GA signaling repressor SPINDLY (SPY). Gallium 64-66 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 50-53 16460863-0 2006 The influence of gallium and other metal ions on the uptake of non-transferrin-bound iron by rat hepatocytes. Gallium 17-24 transferrin Rattus norvegicus 67-78 16679458-6 2006 Genetic and gene expression analyses suggest that GIS acts in a GA-responsive pathway upstream of the trichome initiation regulator GLABROUS1 (GL1) and downstream of the GA signaling repressor SPINDLY (SPY). Gallium 64-66 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 202-205 16679458-7 2006 GIS mediates the induction of GL1 expression by GA in inflorescence organs and is antagonized in its action by the DELLA repressor GAI. Gallium 48-50 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 0-3 16373528-9 2006 Furthermore, because HFE regulates iron and gallium uptake, the two Tf-TfR1-HFE complexes in R cells may be involved in reduced (67)Ga and (59)Fe uptake compared with S cells. Gallium 44-51 homeostatic iron regulator Homo sapiens 21-24 16709201-4 2006 AtGID1b was unique in its binding affinity to GA(4) and in its pH dependence when compared with the other two, by only showing binding in a narrow pH range (pH 6.4-7.5) with 10-fold higher affinity (apparent K(d) for GA(4) = 3 x 10(-8) m) than AtGID1a and AtGID1c. Gallium 46-48 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 0-7 16709201-4 2006 AtGID1b was unique in its binding affinity to GA(4) and in its pH dependence when compared with the other two, by only showing binding in a narrow pH range (pH 6.4-7.5) with 10-fold higher affinity (apparent K(d) for GA(4) = 3 x 10(-8) m) than AtGID1a and AtGID1c. Gallium 217-219 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 0-7 16562970-3 2006 Reaction of the first complex leads to [(Ph3P)2Rh{Ga(DDP)}(mu-Cl)] (1), exhibiting a chloride bridging the gallium and the rhodium atoms, whereas the second complex leads to a full insertion of the Ga(DDP) ligand into the Rh-Cl bond giving [(COE)(benzene)Rh{(DDP)GaCl}] (2) on coordination of the solvent C6H6. Gallium 107-114 translocase of inner mitochondrial membrane 8A Homo sapiens 50-57 16562970-3 2006 Reaction of the first complex leads to [(Ph3P)2Rh{Ga(DDP)}(mu-Cl)] (1), exhibiting a chloride bridging the gallium and the rhodium atoms, whereas the second complex leads to a full insertion of the Ga(DDP) ligand into the Rh-Cl bond giving [(COE)(benzene)Rh{(DDP)GaCl}] (2) on coordination of the solvent C6H6. Gallium 107-114 translocase of inner mitochondrial membrane 8A Homo sapiens 53-56 16549467-5 2006 The infusion of the GA mixture, however, decreased (P < 0.001) the plasma urea concentration and urea entry rate in Otc(spf-ash) mice compared with controls. Gallium 20-22 ornithine transcarbamylase Mus musculus 119-122 16499355-3 2006 The gallium complex [GaL2]Cl.2.5H2O, the metal-free ligand (HL), and the starting compound used for the preparation of HL were assessed in vitro for their cytotoxicity in a panel of human tumor cell lines. Gallium 4-11 galectin 2 Homo sapiens 21-25 16460513-7 2006 Phenotypic characterization and quantitative analysis of the endogenous GA content of ga3ox1 and ga3ox2 single and ga3ox1/ga3ox2 double mutants revealed distinct as well as overlapping roles of AtGA3ox1 and AtGA3ox2 in Arabidopsis development. Gallium 72-74 gibberellin 3-oxidase 1 Arabidopsis thaliana 86-92 16460513-7 2006 Phenotypic characterization and quantitative analysis of the endogenous GA content of ga3ox1 and ga3ox2 single and ga3ox1/ga3ox2 double mutants revealed distinct as well as overlapping roles of AtGA3ox1 and AtGA3ox2 in Arabidopsis development. Gallium 72-74 gibberellin 3-oxidase 2 Arabidopsis thaliana 97-103 16460513-9 2006 The stage-specific severe GA-deficient phenotypes of the ga3ox1/ga3ox2 mutant suggest that AtGA3ox3 and AtGA3ox4 are tightly regulated by developmental cues; AtGA3ox3 and AtGA3ox4 are not upregulated to compensate for GA deficiency during vegetative growth of the double mutant. Gallium 26-28 gibberellin 3-oxidase 1 Arabidopsis thaliana 57-70 16460513-9 2006 The stage-specific severe GA-deficient phenotypes of the ga3ox1/ga3ox2 mutant suggest that AtGA3ox3 and AtGA3ox4 are tightly regulated by developmental cues; AtGA3ox3 and AtGA3ox4 are not upregulated to compensate for GA deficiency during vegetative growth of the double mutant. Gallium 26-28 gibberellin 3-oxidase 3 Arabidopsis thaliana 91-99 16460513-9 2006 The stage-specific severe GA-deficient phenotypes of the ga3ox1/ga3ox2 mutant suggest that AtGA3ox3 and AtGA3ox4 are tightly regulated by developmental cues; AtGA3ox3 and AtGA3ox4 are not upregulated to compensate for GA deficiency during vegetative growth of the double mutant. Gallium 26-28 gibberellin 3-oxidase 4 Arabidopsis thaliana 104-112 16460513-9 2006 The stage-specific severe GA-deficient phenotypes of the ga3ox1/ga3ox2 mutant suggest that AtGA3ox3 and AtGA3ox4 are tightly regulated by developmental cues; AtGA3ox3 and AtGA3ox4 are not upregulated to compensate for GA deficiency during vegetative growth of the double mutant. Gallium 26-28 gibberellin 3-oxidase 3 Arabidopsis thaliana 158-166 16460513-9 2006 The stage-specific severe GA-deficient phenotypes of the ga3ox1/ga3ox2 mutant suggest that AtGA3ox3 and AtGA3ox4 are tightly regulated by developmental cues; AtGA3ox3 and AtGA3ox4 are not upregulated to compensate for GA deficiency during vegetative growth of the double mutant. Gallium 26-28 gibberellin 3-oxidase 4 Arabidopsis thaliana 171-179 16403494-3 2006 A gene was constructed to encode barley alpha-amylase 1 (AMY1) fused C-terminally to this SBD via a 37 residue GA-I linker segment. Gallium 111-113 LOC548210 Hordeum vulgare 40-55 16403494-3 2006 A gene was constructed to encode barley alpha-amylase 1 (AMY1) fused C-terminally to this SBD via a 37 residue GA-I linker segment. Gallium 111-113 LOC548210 Hordeum vulgare 57-61 16422638-1 2006 Detailed theoretical and experimental investigations have been presented on a novel binuclear gallium complex Ga2(saph)2q2, a potentially active and novel material for organic light-emitting diodes (OLEDs). Gallium 94-101 electron transfer flavoprotein subunit alpha Homo sapiens 110-113 16373528-9 2006 Furthermore, because HFE regulates iron and gallium uptake, the two Tf-TfR1-HFE complexes in R cells may be involved in reduced (67)Ga and (59)Fe uptake compared with S cells. Gallium 44-51 transferrin receptor Homo sapiens 71-75 16326028-10 2006 Our hypothesis may also partially explain why gallium, an atomically iron-like toxic metal that binds to transferrin and the TfR is incorporated into cells and was previously demonstrated to have anti-tumor activity in patients with lymphomas refractory to other chemotherapeutic treatments. Gallium 46-53 transferrin Homo sapiens 105-116 16936323-1 2006 2"-O-methyl-RNAs incorporating 3-deazaguanine (c3G) were synthesized by use of N,N-diphenylcarbamoyl and N,N-dimethylaminomethylene as its base protecting groups to suppress sheared-type 5"-GA-3"/5"-GA-3" tandem mismatched base pairing which requires the N3 atom. Gallium 190-192 Rap guanine nucleotide exchange factor 1 Homo sapiens 47-50 16936323-1 2006 2"-O-methyl-RNAs incorporating 3-deazaguanine (c3G) were synthesized by use of N,N-diphenylcarbamoyl and N,N-dimethylaminomethylene as its base protecting groups to suppress sheared-type 5"-GA-3"/5"-GA-3" tandem mismatched base pairing which requires the N3 atom. Gallium 199-201 Rap guanine nucleotide exchange factor 1 Homo sapiens 47-50 16326028-10 2006 Our hypothesis may also partially explain why gallium, an atomically iron-like toxic metal that binds to transferrin and the TfR is incorporated into cells and was previously demonstrated to have anti-tumor activity in patients with lymphomas refractory to other chemotherapeutic treatments. Gallium 46-53 transferrin receptor Homo sapiens 125-128 16269603-6 2005 Binding specificity, affinity, internalization, and retention of (68)Ga-DOTA-hEGF was studied in 2 EGFR-expressing cell lines, U343 glioma cells and A431 cervical carcinoma cells. Gallium 69-71 epidermal growth factor Homo sapiens 77-81 16365293-3 2005 Glatiramer acetate [(GA) Copaxone], an approved drug for the treatment of multiple sclerosis, has been shown to induce Th2/3 cells that accumulate in the CNS, expressing in situ antiinflammatory cytokines and BDNF. Gallium 20-24 brain derived neurotrophic factor Mus musculus 209-213 16365293-4 2005 In the present study, we investigated whether s.c. injections of GA, applied at various stages of experimental autoimmune encephalomyelitis, affect the expression of NTs, particularly BDNF, in the brain. Gallium 65-67 brain derived neurotrophic factor Mus musculus 184-188 16365293-6 2005 In contrast, GA treatment led to sustained augmentation in the expression of BDNF, NT-3, and NT-4 in various brain regions as demonstrated by histological analysis of immunostained brain sections. Gallium 13-15 brain derived neurotrophic factor Mus musculus 77-81 16365293-10 2005 Of importance, in GA-treated mice, intense BDNF expression was manifested by neuronal progenitors that migrated into lesions in injured regions. Gallium 18-20 brain derived neurotrophic factor Mus musculus 43-47 16384500-0 2005 Role of defect sites and Ga polarization in the magnetism of Mn-doped GaN. Gallium 25-27 gigaxonin Homo sapiens 70-73 16235193-6 2005 We discuss as a possible solution to this paradoxical situation that EL2+ is an isolated antisite at room temperature, which at low temperature, where all magnetic resonance experiments are performed, associates itself with shallow acceptors such as Zn(Ga)- more than two nearest neighbour distances away. Gallium 253-255 spectrin alpha, erythrocytic 1 Homo sapiens 69-72 16292477-1 2005 PURPOSE: The aim of the study is to assess the feasibility of imaging specific activity of myeloperoxidase (MPO), a leukocyte enzyme with important roles in inflammation and atherosclerosis, by single photon emission computed tomography (SPECT) using a novel (67)Ga-labeled radiotracer obtained by conjugating desferrioxamine (DF) and hydroxyindolyl acetic acid in vivo. Gallium 263-265 myeloperoxidase Mus musculus 91-106 16292477-1 2005 PURPOSE: The aim of the study is to assess the feasibility of imaging specific activity of myeloperoxidase (MPO), a leukocyte enzyme with important roles in inflammation and atherosclerosis, by single photon emission computed tomography (SPECT) using a novel (67)Ga-labeled radiotracer obtained by conjugating desferrioxamine (DF) and hydroxyindolyl acetic acid in vivo. Gallium 263-265 myeloperoxidase Mus musculus 108-111 15876695-3 2005 The three independent Ga atoms are located on sites with imposed symmetry 2 (Wickoff positions 4a for Ga1 and 4b for Ga2 and Ga3). Gallium 22-24 electron transfer flavoprotein subunit alpha Homo sapiens 117-128 15925514-2 2005 The human serum iron transport protein transferrin (Tf) can bind to many metals including gallium and cobalt. Gallium 90-97 transferrin Homo sapiens 39-50 15925514-2 2005 The human serum iron transport protein transferrin (Tf) can bind to many metals including gallium and cobalt. Gallium 90-97 transferrin Homo sapiens 52-54 15861481-7 2005 Accordingly, for the Ga atom in its excited 2S state, the Ga-N2 bond energy can be estimated to be around 79 kJ mol(-1). Gallium 21-23 DDB1 and CUL4 associated factor 8 Homo sapiens 58-63 15870903-3 2005 We investigated the role of 18 beta-glycyrrhetinic acid (GA), a saponin isolated from licorice roots, on TNF-alpha-induced IL-8 production in human colonic epithelial cells. Gallium 57-59 tumor necrosis factor Homo sapiens 105-114 15870903-3 2005 We investigated the role of 18 beta-glycyrrhetinic acid (GA), a saponin isolated from licorice roots, on TNF-alpha-induced IL-8 production in human colonic epithelial cells. Gallium 57-59 C-X-C motif chemokine ligand 8 Homo sapiens 123-127 15870903-6 2005 GA suppressed TNF-alpha-induced IL-8 production in a concentration-dependent manner. Gallium 0-2 tumor necrosis factor Homo sapiens 14-23 15870903-6 2005 GA suppressed TNF-alpha-induced IL-8 production in a concentration-dependent manner. Gallium 0-2 C-X-C motif chemokine ligand 8 Homo sapiens 32-36 15870903-7 2005 In addition, GA inhibited TNF-alpha-induced phosphorylation of p38 MAPK and extracellular-regulated kinases (ERK), I kappa B alpha degradation, and NF-kappa B activation. Gallium 13-15 tumor necrosis factor Homo sapiens 26-35 15870903-7 2005 In addition, GA inhibited TNF-alpha-induced phosphorylation of p38 MAPK and extracellular-regulated kinases (ERK), I kappa B alpha degradation, and NF-kappa B activation. Gallium 13-15 NFKB inhibitor alpha Homo sapiens 115-130 15870903-7 2005 In addition, GA inhibited TNF-alpha-induced phosphorylation of p38 MAPK and extracellular-regulated kinases (ERK), I kappa B alpha degradation, and NF-kappa B activation. Gallium 13-15 nuclear factor kappa B subunit 1 Homo sapiens 148-158 15870903-8 2005 These results suggest that GA has the inhibitory effects on TNF-alpha-induced IL-8 production in the intestinal epithelial cells through blockade in the phosphorylation of MAPKs, following I kappa B alpha degradation and NF-kappa B activation. Gallium 27-29 tumor necrosis factor Homo sapiens 60-69 15870903-8 2005 These results suggest that GA has the inhibitory effects on TNF-alpha-induced IL-8 production in the intestinal epithelial cells through blockade in the phosphorylation of MAPKs, following I kappa B alpha degradation and NF-kappa B activation. Gallium 27-29 C-X-C motif chemokine ligand 8 Homo sapiens 78-82 15870903-8 2005 These results suggest that GA has the inhibitory effects on TNF-alpha-induced IL-8 production in the intestinal epithelial cells through blockade in the phosphorylation of MAPKs, following I kappa B alpha degradation and NF-kappa B activation. Gallium 27-29 NFKB inhibitor alpha Homo sapiens 189-204 15870903-8 2005 These results suggest that GA has the inhibitory effects on TNF-alpha-induced IL-8 production in the intestinal epithelial cells through blockade in the phosphorylation of MAPKs, following I kappa B alpha degradation and NF-kappa B activation. Gallium 27-29 nuclear factor kappa B subunit 1 Homo sapiens 221-231 32689188-5 2005 Measurement of endogenous gibberellin (GA) showed that bioactive GA4 levels in mutant plants were reduced compared with wild type (WT) plants. Gallium 39-41 gibberellin 3-oxidase 1 Arabidopsis thaliana 65-68 32689188-6 2005 Like other known mutants defective in GA biosynthesis, the late-flowering phenotype observed in our T-DNA-tagged line could be largely repressed by application of exogenous GA3. Gallium 38-40 GA requiring 3 Arabidopsis thaliana 173-176 16167898-6 2005 RGL2 undergoes GA-induced degradation, and this process is blocked by proteasome inhibitors and serine/threonine phosphatase inhibitors; however, serine/threonine kinase inhibitors had no detectable effect, suggesting that dephosphorylation of serine/threonine is probably a prerequisite for degradation of RGL2 via the proteasome pathway. Gallium 15-17 RGA-like 2 Arabidopsis thaliana 0-4 15777326-3 2005 HGF were exposed to gallium-aluminum-arsenide diode laser at dosages of 1.5 or 3 J/cm(2) and then cultured on commercially pure titanium discs. Gallium 20-27 hepatocyte growth factor Homo sapiens 0-3 15921034-0 2005 Gallium-inducible transferrin-independent iron acquisition is a property of many cell types: possible role of alterations in the plasma membrane. Gallium 0-7 transferrin Homo sapiens 18-29 15651855-0 2005 Insertion of Ga(DDP) into the Au-Cl bond of (PPh3)AuCl: a first structurally characterized Au-Ga bond. Gallium 13-15 translocase of inner mitochondrial membrane 8A Homo sapiens 16-19 15651855-0 2005 Insertion of Ga(DDP) into the Au-Cl bond of (PPh3)AuCl: a first structurally characterized Au-Ga bond. Gallium 13-15 caveolin 1 Homo sapiens 45-49 15651855-0 2005 Insertion of Ga(DDP) into the Au-Cl bond of (PPh3)AuCl: a first structurally characterized Au-Ga bond. Gallium 94-96 translocase of inner mitochondrial membrane 8A Homo sapiens 16-19 15651855-0 2005 Insertion of Ga(DDP) into the Au-Cl bond of (PPh3)AuCl: a first structurally characterized Au-Ga bond. Gallium 94-96 caveolin 1 Homo sapiens 45-49 15324308-7 2005 Competitive binding occurs exclusively within the RGS domain and involves a cluster of positively charged residues located on the surface opposite to the Ga interaction site. Gallium 154-156 paired like homeodomain 2 Homo sapiens 50-53 15653666-13 2005 In addition, (68)Ga-DOTA-based bombesin derivatives are being investigated with some success in patients with prostate cancer. Gallium 17-19 gastrin releasing peptide Homo sapiens 31-39 15634200-3 2005 The tir3-1 allele of BIG reduces the response of plants to application of the gibberellin (GA) precursors ent-kaurenoic acid and GA12 and its semidwarf phenotype is partially reversed by C19-GAs. Gallium 91-93 auxin transport protein (BIG) Arabidopsis thaliana 4-8 15608330-1 2005 SPINDLY (SPY) is a negative regulator of gibberellin (GA) responses; however, spy mutants exhibit various phenotypic alterations not found in GA-treated plants. Gallium 54-56 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 0-7 15608330-1 2005 SPINDLY (SPY) is a negative regulator of gibberellin (GA) responses; however, spy mutants exhibit various phenotypic alterations not found in GA-treated plants. Gallium 54-56 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 9-12 15608330-1 2005 SPINDLY (SPY) is a negative regulator of gibberellin (GA) responses; however, spy mutants exhibit various phenotypic alterations not found in GA-treated plants. Gallium 54-56 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 78-81 15634200-5 2005 1-N-naphthylphthalamic acid (NPA) and triiodobenzoic acid lead to overexpression of the GA-biosynthetic gene AtGA20ox1 comparable in magnitude to the overexpression observed in seedlings treated with paclobutrazol, a GA biosynthesis inhibitor. Gallium 88-90 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 109-118 15608330-3 2005 GA also repressed the effects of cytokinin, suggesting that there is cross talk between the two hormone-response pathways, which may involve SPY function. Gallium 0-2 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 141-144 15608330-8 2005 Our results demonstrate that SPY acts as both a repressor of GA responses and a positive regulator of cytokinin signaling. Gallium 61-63 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 29-32 15454116-7 2004 18alpha,beta-Glycyrrhetic acid (GA) did not inhibit IL-8 but inhibited eotaxin 1. Gallium 32-34 C-C motif chemokine ligand 11 Homo sapiens 71-80 15627016-8 2004 Gallium"s mechanisms of action include its binding to transferrin, targeting to transferrin receptors on lymphoma cells, and inhibiting ribonucleotide reductase. Gallium 0-7 transferrin Homo sapiens 54-65 15627016-8 2004 Gallium"s mechanisms of action include its binding to transferrin, targeting to transferrin receptors on lymphoma cells, and inhibiting ribonucleotide reductase. Gallium 0-7 transferrin Homo sapiens 80-91 15651176-3 2004 Gallium shares certain chemical properties with iron; therefore, it binds avidly to the iron transport protein transferrin. Gallium 0-7 transferrin Homo sapiens 111-122 15651176-4 2004 Transferrin-gallium complexes preferentially target cells that express transferrin receptors on their surface. Gallium 12-19 transferrin Homo sapiens 0-11 15651176-4 2004 Transferrin-gallium complexes preferentially target cells that express transferrin receptors on their surface. Gallium 12-19 transferrin Homo sapiens 71-82 15516508-4 2004 In addition, we show that the formation of ectopic trichome cells on lec2 and fus3 embryos is a GA-dependent process as in true leaves, suggesting that the GA pathway is misactivated in embryonic mutants. Gallium 96-98 AP2/B3-like transcriptional factor family protein Arabidopsis thaliana 69-73 15516508-4 2004 In addition, we show that the formation of ectopic trichome cells on lec2 and fus3 embryos is a GA-dependent process as in true leaves, suggesting that the GA pathway is misactivated in embryonic mutants. Gallium 96-98 AP2/B3-like transcriptional factor family protein Arabidopsis thaliana 78-82 15516508-4 2004 In addition, we show that the formation of ectopic trichome cells on lec2 and fus3 embryos is a GA-dependent process as in true leaves, suggesting that the GA pathway is misactivated in embryonic mutants. Gallium 156-158 AP2/B3-like transcriptional factor family protein Arabidopsis thaliana 69-73 15516508-4 2004 In addition, we show that the formation of ectopic trichome cells on lec2 and fus3 embryos is a GA-dependent process as in true leaves, suggesting that the GA pathway is misactivated in embryonic mutants. Gallium 156-158 AP2/B3-like transcriptional factor family protein Arabidopsis thaliana 78-82 15516508-5 2004 We next demonstrate that the GA-biosynthesis gene AtGA3ox2, which encodes the key enzyme AtGA3ox2 that catalyzes the conversion of inactive to bioactive GAs, is ectopically activated in embryos of the two mutants. Gallium 29-31 gibberellin 3-oxidase 2 Arabidopsis thaliana 50-58 15516508-5 2004 We next demonstrate that the GA-biosynthesis gene AtGA3ox2, which encodes the key enzyme AtGA3ox2 that catalyzes the conversion of inactive to bioactive GAs, is ectopically activated in embryos of the two mutants. Gallium 29-31 gibberellin 3-oxidase 2 Arabidopsis thaliana 89-97 15367002-12 2004 This work shows that the Ga atom at its first excited state in the presence of silane molecules in gas phase leads to the formation of SiH(3) radicals, H atoms, GaH hydrides, as well as gallium silicide molecules. Gallium 25-27 guanine deaminase Homo sapiens 161-164 15261817-7 2004 The relationship between gibberallic acid (GA) and LFY expression was also revealed by this method. Gallium 43-45 floral meristem identity control protein LEAFY (LFY) Arabidopsis thaliana 51-54 15509835-4 2004 When GfCPS/KS was overexpressed and targeted to plastids, a range of GA-deficient phenotypes of the ga1-3 and ga2-1 mutants (defective in CPS and KS, respectively) were restored to wild type. Gallium 69-71 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 100-105 15347799-2 2004 Many, if not all, GA-dependent responses require SPY protein, and to improve our understanding of how the SPY signaling pathway operates, a yeast two-hybrid screen was used to identify both upstream and downstream components that might regulate the activity of the HvSPY protein. Gallium 18-20 Tetratricopeptide repeat (TPR)-like superfamily protein Arabidopsis thaliana 49-52 15308775-6 2004 Overexpression of SLY1 in sly1-2 and sly1-10 plants rescues the recessive GA-insensitive phenotype of these mutants. Gallium 74-76 F-box family protein Arabidopsis thaliana 18-22 15107994-5 2004 This suggests that mutation in the MS33 gene may suppress the GA biosynthetic pathway that leads to GA4 via GA9 and the early 13-H C20 GAs. Gallium 62-64 gibberellin 3-oxidase 1 Arabidopsis thaliana 100-103 15305020-1 2004 We recently suggested that the transferrin (Tf)-gallium-67 (67Ga) complex dissociated on the surface of the hepatocytes after partial hepatectomy and free 67Ga bound to heparan sulfate in the extracellular matrix. Gallium 48-55 transferrin Rattus norvegicus 31-42 15305020-1 2004 We recently suggested that the transferrin (Tf)-gallium-67 (67Ga) complex dissociated on the surface of the hepatocytes after partial hepatectomy and free 67Ga bound to heparan sulfate in the extracellular matrix. Gallium 48-55 transferrin Rattus norvegicus 44-46