PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
7050281-0	1982	Localization of thioesterase II, the chain-length regulatory enzyme of milk fatty acid synthesis, in rat mammary gland epithelial cells.	milk fatty acid	71-86	oleoyl-ACP hydrolase	Rattus norvegicus	16-31
32824948-0	2020	Associations between the Bovine Myostatin Gene and Milk Fatty Acid Composition in New Zealand Holstein-Friesian x Jersey-Cross Cows.	milk fatty acid	51-66	myostatin	Bos taurus	32-41
33178884-0	2020	Variation in the stearoyl-CoA desaturase gene (SCD) and its influence on milk fatty acid composition in late-lactation dairy cattle grazed on pasture.	milk fatty acid	73-88	stearoyl-CoA desaturase	Bos taurus	17-40
33178884-0	2020	Variation in the stearoyl-CoA desaturase gene (SCD) and its influence on milk fatty acid composition in late-lactation dairy cattle grazed on pasture.	milk fatty acid	73-88	stearoyl-CoA desaturase	Bos taurus	47-50
31419940-0	2019	Polymorphisms and genetic effects of PRLR, MOGAT1, MINPP1 and CHUK genes on milk fatty acid traits in Chinese Holstein.	milk fatty acid	76-91	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	62-66
31419940-1	2019	BACKGROUND: Our initial genome-wide association study (GWAS) identified 20 promising candidate genes for milk fatty acid (FA) traits in a Chinese Holstein population, including PRLR, MOGAT1, MINPP1 and CHUK genes.	milk fatty acid	105-120	prolactin receptor	Homo sapiens	177-181
31419940-1	2019	BACKGROUND: Our initial genome-wide association study (GWAS) identified 20 promising candidate genes for milk fatty acid (FA) traits in a Chinese Holstein population, including PRLR, MOGAT1, MINPP1 and CHUK genes.	milk fatty acid	105-120	monoacylglycerol O-acyltransferase 1	Homo sapiens	183-189
31419940-1	2019	BACKGROUND: Our initial genome-wide association study (GWAS) identified 20 promising candidate genes for milk fatty acid (FA) traits in a Chinese Holstein population, including PRLR, MOGAT1, MINPP1 and CHUK genes.	milk fatty acid	105-120	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	202-206
30660714-4	2019	Azgp1-/- mice were compared to wild-type to determine its effects on milk fatty acid composition and offspring growth.	milk fatty acid	69-84	alpha-2-glycoprotein 1, zinc	Mus musculus	0-5
28601449-13	2017	In conclusion, the addition of chia seeds at the CHigh level in dairy goat diets negatively affected in vitro rumen fermentation, but increased the milk fatty acid profile of C18:0, C18:1n-9 cis, and C:20, monounsaturated fatty acids, and polyunsaturated fatty acids.	milk fatty acid	148-163	acidic mammalian chitinase	Capra hircus	31-35
29569734-0	2018	Remarkable genetic diversity detected at river buffalo prolactin receptor (PRLR) gene and association studies with milk fatty acid composition.	milk fatty acid	115-130	prolactin receptor	Bubalus bubalis	55-73
29569734-0	2018	Remarkable genetic diversity detected at river buffalo prolactin receptor (PRLR) gene and association studies with milk fatty acid composition.	milk fatty acid	115-130	prolactin receptor	Bubalus bubalis	75-79
29230020-0	2017	SNP co-association and network analyses identify E2F3, KDM5A and BACH2 as key regulators of the bovine milk fatty acid profile.	milk fatty acid	103-118	E2F transcription factor 3	Bos taurus	49-53
29230020-0	2017	SNP co-association and network analyses identify E2F3, KDM5A and BACH2 as key regulators of the bovine milk fatty acid profile.	milk fatty acid	103-118	lysine demethylase 5A	Bos taurus	55-60
29230020-0	2017	SNP co-association and network analyses identify E2F3, KDM5A and BACH2 as key regulators of the bovine milk fatty acid profile.	milk fatty acid	103-118	BTB domain and CNC homolog 2	Bos taurus	65-70
28524009-0	2017	A novel polymorphism in the oxytocin receptor encoding gene (OXTR) affects milk fatty acid composition in Italian Mediterranean river buffalo.	milk fatty acid	75-90	oxytocin receptor	Bubalus bubalis	61-65
28524009-10	2017	The results of this study suggest that the OXTR CC animals might be useful in selection toward the improvement of milk fatty acid composition.	milk fatty acid	114-129	oxytocin receptor	Bubalus bubalis	43-47
28252355-7	2017	Milk fatty acid profile can be improved by administrating a moderate level of flaxseed in the diet, however, milk fatty acid profile from Friesian and Jersey cows showed different contents of C18 : 1 trans-11, SFA and MUFA.	milk fatty acid	109-124	MUFA	Bos taurus	218-222
26970560-3	2016	The aims of this study were to verify whether the SCD gene has significant genetic effects on milk fatty acid composition in dairy cattle.	milk fatty acid	94-109	stearoyl-CoA desaturase	Bos taurus	50-53
26970560-10	2016	In summary, our findings provide replicate evidence for our previous GWAS and demonstrate that variants in the SCD gene are significantly associated with milk fatty acid composition in dairy cattle, which provides clear evidence for an increased understanding of milk fatty acid synthesis and enhances opportunities to improve milk-fat composition in dairy cattle.	milk fatty acid	154-169	stearoyl-CoA desaturase	Bos taurus	111-114
26970560-10	2016	In summary, our findings provide replicate evidence for our previous GWAS and demonstrate that variants in the SCD gene are significantly associated with milk fatty acid composition in dairy cattle, which provides clear evidence for an increased understanding of milk fatty acid synthesis and enhances opportunities to improve milk-fat composition in dairy cattle.	milk fatty acid	263-278	stearoyl-CoA desaturase	Bos taurus	111-114
26851858-2	2016	However, the role of THRSP in regulating the synthesis of milk fatty acid composition in goat mammary gland remains unknown.	milk fatty acid	58-73	thyroid hormone-inducible hepatic protein	Capra hircus	21-26
27468856-9	2016	SNPs within FASN, PPARGC1A, ABCG2 and IGF1 showed significant genetic effects on milk fatty acid composition in dairy cattle, indicating their potential functions in milk fatty acids synthesis and metabolism.	milk fatty acid	81-96	fatty acid synthase	Bos taurus	12-16
27468856-9	2016	SNPs within FASN, PPARGC1A, ABCG2 and IGF1 showed significant genetic effects on milk fatty acid composition in dairy cattle, indicating their potential functions in milk fatty acids synthesis and metabolism.	milk fatty acid	81-96	PPARG coactivator 1 alpha	Bos taurus	18-26
27468856-9	2016	SNPs within FASN, PPARGC1A, ABCG2 and IGF1 showed significant genetic effects on milk fatty acid composition in dairy cattle, indicating their potential functions in milk fatty acids synthesis and metabolism.	milk fatty acid	81-96	ATP binding cassette subfamily G member 2	Bos taurus	28-33
27468856-9	2016	SNPs within FASN, PPARGC1A, ABCG2 and IGF1 showed significant genetic effects on milk fatty acid composition in dairy cattle, indicating their potential functions in milk fatty acids synthesis and metabolism.	milk fatty acid	81-96	insulin like growth factor 1	Bos taurus	38-42
21895781-6	2012	Our results indicate that the effect of Co on milk fatty acid profile is mediated at the post-transcriptional level by reduced activity of SCD in the mammary gland.	milk fatty acid	46-61	stearoyl-CoA desaturase	Bos taurus	139-142
26898284-2	2016	The aim of this study was to estimate effects of the DGAT1 polymorphism on milk fatty acid, protein, and mineral composition.	milk fatty acid	75-90	diacylglycerol O-acyltransferase 1	Bos taurus	53-58
24351793-6	2014	The milk fatty acid pattern showed a highly significant decrease of over 10 % in the amount of saturated fatty acids (SFA) in both oil feedings and a highly significant increase in mono (MUFA) and poly (PUFA) unsaturated fatty acids, conjugated linoleic acids (CLA) included.	milk fatty acid	4-19	MUFA	Bos taurus	187-191
24351793-6	2014	The milk fatty acid pattern showed a highly significant decrease of over 10 % in the amount of saturated fatty acids (SFA) in both oil feedings and a highly significant increase in mono (MUFA) and poly (PUFA) unsaturated fatty acids, conjugated linoleic acids (CLA) included.	milk fatty acid	4-19	PUFA	Bos taurus	203-207
22114848-0	2012	Polymorphisms in genes in the SREBP1 signalling pathway and SCD are associated with milk fatty acid composition in Holstein cattle.	milk fatty acid	84-99	sterol regulatory element binding transcription factor 1	Bos taurus	30-36
22921629-1	2012	We determined the effect of insulin on milk fatty acid (FA) and lipid composition in goats.	milk fatty acid	39-54	insulin	Capra hircus	28-35
22818476-1	2012	In 136 cows with altogether 969 milk samples, we investigated the effect of the acyl-coenzyme A:diacylglycerol acyltransferase 1 (DGAT1) K232A polymorphism on milk fatty acid (FA) composition and how, in combination with copper concentration in milk, this influences the occurrence of spontaneous oxidized flavor.	milk fatty acid	159-174	diacylglycerol O-acyltransferase 1	Bos taurus	130-135
22114848-0	2012	Polymorphisms in genes in the SREBP1 signalling pathway and SCD are associated with milk fatty acid composition in Holstein cattle.	milk fatty acid	84-99	stearoyl-CoA desaturase 5	Bos taurus	60-63
17582140-1	2007	The effect of the stearoyl-CoA desaturase (SCD) gene on milk fatty acid composition was tested.	milk fatty acid	56-71	stearoyl-CoA desaturase	Bos taurus	18-41
21700058-0	2011	Short communication: influence of the muscle hypertrophy mutation of the myostatin gene on milk production traits and milk fatty acid composition in dual-purpose Belgian Blue dairy cattle.	milk fatty acid	118-133	myostatin	Bos taurus	73-82
21700058-1	2011	The objective of this study was to estimate genetic effects for the muscle hypertrophy mutation (mh) of the myostatin gene for conventional milk production traits and for milk fatty acid composition in dual-purpose Belgian Blue dairy cows.	milk fatty acid	171-186	myostatin	Bos taurus	108-117
20723706-0	2010	Association between the polymorphism of the goat stearoyl-CoA desaturase 1 (SCD1) gene and milk fatty acid composition in Murciano-Granadina goats.	milk fatty acid	91-106	stearoyl-CoA desaturase	Capra hircus	49-74
20723706-0	2010	Association between the polymorphism of the goat stearoyl-CoA desaturase 1 (SCD1) gene and milk fatty acid composition in Murciano-Granadina goats.	milk fatty acid	91-106	stearoyl-CoA desaturase	Capra hircus	76-80
20723706-5	2010	Associations with milk fatty acid composition might be explained by the global effects that SCD1 exerts on mammary gland lipid metabolism through the down-modulation of key transcription factors.	milk fatty acid	18-33	stearoyl-CoA desaturase	Capra hircus	92-96
20399061-0	2010	Pleiotropic effects of the goat prolactin receptor genotype on milk fatty acid composition.	milk fatty acid	63-78	prolactin receptor	Capra hircus	32-50
20399061-3	2010	Conversely, and to the best of our knowledge, the effects of PRLR genotype on milk fatty acid content have not been studied so far in any mammalian species.	milk fatty acid	78-93	prolactin receptor	Homo sapiens	61-65
20059933-4	2010	Based on this, we performed a quantitative trait loci (QTL) analysis of an ovine chromosome (22) that harbors the SCD gene for effects on milk fatty acid composition traits and classical milk production traits.	milk fatty acid	138-153	acyl-CoA desaturase	Ovis aries	114-117
19233803-13	2009	The study demonstrated that cows fed a diet low in fiber and low in PUFA may exhibit subacute ruminal acidosis and moderate changes to milk fatty acid profile but without concomitant milk fat depression.	milk fatty acid	135-150	PUFA	Bos taurus	68-72
18483775-5	2008	Milk fatty acid composition for transgenic goats, as determined by gas chromatography, was found to have significantly fewer short chain fatty acids (P < 0.01) and more saturated fatty acids (P < 0.05) compared to controls, suggesting an overall metabolic stress and/or decreased expression of key enzymes (e.g. fatty acid synthase, stearoyl-CoA desaturase).	milk fatty acid	0-15	fatty acid synthase	Capra hircus	318-337
18483775-5	2008	Milk fatty acid composition for transgenic goats, as determined by gas chromatography, was found to have significantly fewer short chain fatty acids (P < 0.01) and more saturated fatty acids (P < 0.05) compared to controls, suggesting an overall metabolic stress and/or decreased expression of key enzymes (e.g. fatty acid synthase, stearoyl-CoA desaturase).	milk fatty acid	0-15	stearoyl-CoA desaturase	Capra hircus	339-362
18420645-0	2008	Milk fatty acid unsaturation: genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and acyl CoA: diacylglycerol acyltransferase 1 (DGAT1).	milk fatty acid	0-15	stearoyl-CoA desaturase	Bos taurus	64-87
18420645-0	2008	Milk fatty acid unsaturation: genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and acyl CoA: diacylglycerol acyltransferase 1 (DGAT1).	milk fatty acid	0-15	stearoyl-CoA desaturase	Bos taurus	89-93
18420645-0	2008	Milk fatty acid unsaturation: genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and acyl CoA: diacylglycerol acyltransferase 1 (DGAT1).	milk fatty acid	0-15	diacylglycerol O-acyltransferase 1	Bos taurus	143-148
18420645-6	2008	We genotyped the cows for the SCD1 A293V and DGAT1 K232A polymorphisms, which are known to alter milk fatty acid composition.	milk fatty acid	97-112	stearoyl-CoA desaturase	Bos taurus	30-34
18420645-6	2008	We genotyped the cows for the SCD1 A293V and DGAT1 K232A polymorphisms, which are known to alter milk fatty acid composition.	milk fatty acid	97-112	diacylglycerol O-acyltransferase 1	Bos taurus	45-50
17582140-1	2007	The effect of the stearoyl-CoA desaturase (SCD) gene on milk fatty acid composition was tested.	milk fatty acid	56-71	stearoyl-CoA desaturase	Bos taurus	43-46
16772575-9	2006	The milk fatty acid composition indicated that delta9-desaturase was reduced significantly for both CLA treatments, but the reduction was greater for the treatment with trans-10, trans-12 CLA.	milk fatty acid	4-19	stearoyl-CoA desaturase	Bos taurus	47-64
16840616-7	2006	Milk fatty acid pairs dependent on Delta(9)-desaturase were decreased over time, with responses reaching a nadir within 6 d of marker administration.	milk fatty acid	0-15	stearoyl-CoA desaturase	Bos taurus	35-54
15377629-0	2004	Hot topic: using a stearoyl-CoA desaturase transgene to alter milk fatty acid composition.	milk fatty acid	62-77	stearoyl-CoA desaturase	Homo sapiens	19-42
34315401-0	2021	Determination of genetic effects and functional SNPs of bovine HTR1B gene on milk fatty acid traits.	milk fatty acid	77-92	5-hydroxytryptamine receptor 1B	Bos taurus	63-68
34315401-4	2021	In this study, we aimed to investigate whether the HTR1B gene had significant genetic effects on milk fatty acid traits.	milk fatty acid	97-112	5-hydroxytryptamine receptor 1B	Bos taurus	51-56