PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
7923575-4	1994	CYP1A1 activity was induced by CdSO4 and monitored by following the O-deethylation of ethoxy fluorescein ethyl ester or of 7-ethoxyresorufin.	cadmium sulfate	31-36	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	0-6
7532934-7	1995	Short-term induction of the MT IIA promoter by CdSO4 or CdCl2 leads to a shift in tissue specificity and does not increase ectopic expression in tissues where the transgene is active in the noninduced state.	cadmium sulfate	47-52	ATPase, class II, type 9A	Mus musculus	31-34
7923575-5	1994	Induced CYP1A1 activities were similar in both cell lines and were dependent on CdSO4 concentration and induction time.	cadmium sulfate	80-85	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	8-14
7923575-6	1994	Maximal CYP1A1 activities were obtained in 4-6 h with 5-7 microM CdSO4.	cadmium sulfate	65-70	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	8-14
8061521-4	1994	When expressed in an MT-deficient (cup1 delta) mutant of yeast, both MT1 and MT2 complemented the cup1 delta mutation, providing a high level of resistance to CuSO4 and moderate resistance to CdSO4.	cadmium sulfate	192-197	metallothionein CUP1	Saccharomyces cerevisiae S288C	35-39
8061521-4	1994	When expressed in an MT-deficient (cup1 delta) mutant of yeast, both MT1 and MT2 complemented the cup1 delta mutation, providing a high level of resistance to CuSO4 and moderate resistance to CdSO4.	cadmium sulfate	192-197	metallothionein 1A	Arabidopsis thaliana	69-72
8061521-5	1994	Although the MT-deficient yeast was not viable in the presence of either 300 microM CuSO4 or 5 microM CdSO4, cells expressing MT1 were able to grow in medium supplemented with 3 mM CuSO4 and 10 microM CdSO4, and those expressing MT2 grew in the presence of 3 mM CuSO4 and 100 microM CdSO4.	cadmium sulfate	201-206	metallothionein 1A	Arabidopsis thaliana	126-129
8061521-5	1994	Although the MT-deficient yeast was not viable in the presence of either 300 microM CuSO4 or 5 microM CdSO4, cells expressing MT1 were able to grow in medium supplemented with 3 mM CuSO4 and 10 microM CdSO4, and those expressing MT2 grew in the presence of 3 mM CuSO4 and 100 microM CdSO4.	cadmium sulfate	201-206	metallothionein 1A	Arabidopsis thaliana	126-129
2002259-5	1991	Exposure of these cells to weak inducing agents such as heat or cadmium sulphate resulted in the synthesis of HSP72 and HSP90, whereas HSP28 and HSP116 synthesis was detected in keratinocytes and fibroblasts following exposure to the strong inducing agent sodium arsenite.	cadmium sulfate	64-80	heat shock protein family A (Hsp70) member 1A	Homo sapiens	110-115
8441385-5	1993	Also, HSF1 undergoes phosphorylation in cells exposed to heat or cadmium sulfate but not in cells treated with the amino acid analog L-azetidine-2-carboxylic acid, indicating that phosphorylation of HSF1 is not essential for its activation.	cadmium sulfate	65-80	heat shock factor 1	Mus musculus	6-10
2002259-5	1991	Exposure of these cells to weak inducing agents such as heat or cadmium sulphate resulted in the synthesis of HSP72 and HSP90, whereas HSP28 and HSP116 synthesis was detected in keratinocytes and fibroblasts following exposure to the strong inducing agent sodium arsenite.	cadmium sulfate	64-80	heat shock protein 90 alpha family class A member 1	Homo sapiens	120-125
1815469-1	1991	The effect of 90-days treatment with Co(NO3)2, NiSO4, CdSO4, ZnSO4 and HgCL2 on the rat liver cytochrome P-450 linked monooxygenases was studied.	cadmium sulfate	54-59	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	94-110
30914357-4	2019	Cells were pre-protected with C3G (5-160 mumol/L) for 2 h and then treated with cadmium sulfate (CdSO4) (10-160 mumol/L) for 24 h. The results showed that cytotoxicity, mitochondrial damage, superoxide dismutase 2 (SOD2), and overproduction of reactive oxygen species (ROS) in CdSO4-treated R2C cells were significantly reduced with C3G pre-treatment.	cadmium sulfate	97-102	superoxide dismutase 2	Rattus norvegicus	191-213
34433897-8	2021	Moreover, the plant protein were significantly increased by 60% in T6 (0.25 mg kg-1 of CdSO4 + inoculated seed) and Peroxidase dismutase (POD) was also significantly higher by 346% in T6 (0.25 mg kg-1 of CdSO4 + inoculated seed), however, the Superoxide dismutase (SOD) was significantly higher in T5 (0.75 mg kg-1 of CdSO4 + uninoculated seed) and was 769% higher as compared to control.	cadmium sulfate	204-209	superoxide dismutase	Zea mays	243-263
34433897-8	2021	Moreover, the plant protein were significantly increased by 60% in T6 (0.25 mg kg-1 of CdSO4 + inoculated seed) and Peroxidase dismutase (POD) was also significantly higher by 346% in T6 (0.25 mg kg-1 of CdSO4 + inoculated seed), however, the Superoxide dismutase (SOD) was significantly higher in T5 (0.75 mg kg-1 of CdSO4 + uninoculated seed) and was 769% higher as compared to control.	cadmium sulfate	318-323	superoxide dismutase	Zea mays	243-263
2479474-2	1989	C/CDP-2 was cross-resistant to carboplatin, L-phenylalanine mustard (melphalan), and CdSO4, but not to other anticancer agents.	cadmium sulfate	85-90	cut like homeobox 2	Homo sapiens	2-7
33639196-4	2021	Furthermore, the detection data revealed that levels of m6A modification, methyltransferase-like 3 (METTL3) and fat mass and obesity-associated protein (FTO) were all significantly decreased in CdSO4-induced oxidative damage, which was demonstrated by increasing ROS accumulation and MDA contents as well as decreasing SOD activities.	cadmium sulfate	194-199	methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit	Homo sapiens	74-98
33639196-4	2021	Furthermore, the detection data revealed that levels of m6A modification, methyltransferase-like 3 (METTL3) and fat mass and obesity-associated protein (FTO) were all significantly decreased in CdSO4-induced oxidative damage, which was demonstrated by increasing ROS accumulation and MDA contents as well as decreasing SOD activities.	cadmium sulfate	194-199	methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit	Homo sapiens	100-106
33639196-4	2021	Furthermore, the detection data revealed that levels of m6A modification, methyltransferase-like 3 (METTL3) and fat mass and obesity-associated protein (FTO) were all significantly decreased in CdSO4-induced oxidative damage, which was demonstrated by increasing ROS accumulation and MDA contents as well as decreasing SOD activities.	cadmium sulfate	194-199	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	112-151
33639196-4	2021	Furthermore, the detection data revealed that levels of m6A modification, methyltransferase-like 3 (METTL3) and fat mass and obesity-associated protein (FTO) were all significantly decreased in CdSO4-induced oxidative damage, which was demonstrated by increasing ROS accumulation and MDA contents as well as decreasing SOD activities.	cadmium sulfate	194-199	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	153-156
30914357-4	2019	Cells were pre-protected with C3G (5-160 mumol/L) for 2 h and then treated with cadmium sulfate (CdSO4) (10-160 mumol/L) for 24 h. The results showed that cytotoxicity, mitochondrial damage, superoxide dismutase 2 (SOD2), and overproduction of reactive oxygen species (ROS) in CdSO4-treated R2C cells were significantly reduced with C3G pre-treatment.	cadmium sulfate	97-102	superoxide dismutase 2	Rattus norvegicus	215-219
30914357-4	2019	Cells were pre-protected with C3G (5-160 mumol/L) for 2 h and then treated with cadmium sulfate (CdSO4) (10-160 mumol/L) for 24 h. The results showed that cytotoxicity, mitochondrial damage, superoxide dismutase 2 (SOD2), and overproduction of reactive oxygen species (ROS) in CdSO4-treated R2C cells were significantly reduced with C3G pre-treatment.	cadmium sulfate	97-102	Rap guanine nucleotide exchange factor 1	Rattus norvegicus	333-336
29526093-6	2018	Furthermore, by using the mutant strains deficient in catalase, superoxide dismutase, or glutathione synthase, NBT, 5-DN, and TAN appear to contribute to the increased tolerance by activating cytosolic catalase under CCl4, while the antioxidant protection conferred by 5-DT against H2O2 and CdSO4 seems to require cytosolic catalase and glutathione, respectively.	cadmium sulfate	291-296	glutathione synthase	Saccharomyces cerevisiae S288C	89-109
25183031-6	2014	Co-treatment of CdSO4 and ANF significantly down-regulated the mRNA level of multidrug resistance-associated protein (mrp) 1 and cytochrome P450 (cyp) 1a, which constituted the protective mechanisms for zebrafish embryos to chemical toxins.	cadmium sulfate	16-21	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	Danio rerio	77-124
26726675-3	2015	This study explored the effects of ammonium sulfate on the CdS film produced by CBD using cadmium sulfate as the cadmium source.	cadmium sulfate	90-105	CDP-diacylglycerol synthase 1	Homo sapiens	59-62
26726675-6	2015	Agglomeration of CdS particles that is usually present in films deposited using cadmium sulfate as a precursor was also noticeably reduced.	cadmium sulfate	80-95	CDP-diacylglycerol synthase 1	Homo sapiens	17-20
25183031-6	2014	Co-treatment of CdSO4 and ANF significantly down-regulated the mRNA level of multidrug resistance-associated protein (mrp) 1 and cytochrome P450 (cyp) 1a, which constituted the protective mechanisms for zebrafish embryos to chemical toxins.	cadmium sulfate	16-21	cytochrome P450, family 1, subfamily A	Danio rerio	129-153
15542109-3	2004	This study was undertaken to investigate the ability of cadmium chloride (CdCl(2)) and cadmium sulphate (CdSO(4)) to induce point mutations in codon 12 of the K-ras protooncogene assessed by polymerase chain reaction-single strand conformation polymorphisms (PCR-SSCP) and RFLP-enriched PCR methods.	cadmium sulfate	87-103	KRAS proto-oncogene, GTPase	Homo sapiens	159-164
22171716-4	2012	Nanocrystal CdS can be reduced from CdSO(4) at a high solvothermal temperature of 350  C, and the TiO(2)/CdS nanocomposite spheres prepared by this method exhibit superior visible-light-driven photocatalytic efficiency because of its effective heterointerface and high crystallinity.	cadmium sulfate	36-43	CDP-diacylglycerol synthase 1	Homo sapiens	12-15
18541455-1	2008	Nanoparticles of CdS were prepared at 303 K by aqueous precipitation method using CdSO4 and (NH4)2S in presence of the stabilizing agent thioglycerol.	cadmium sulfate	82-87	CDP-diacylglycerol synthase 1	Homo sapiens	17-20
16929849-2	2006	Fusion protein GST-Cd2+-hMT-3 was expressed after isopropyl-beta-D-thiogalactopyranoside (IPTG) induction and addition of 0.1 mmol/L CdSO4 into the culture medium, and mainly existed in cellular soluble fraction as revealed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis.	cadmium sulfate	133-138	glutathione S-transferase kappa 1	Homo sapiens	15-18
16929849-2	2006	Fusion protein GST-Cd2+-hMT-3 was expressed after isopropyl-beta-D-thiogalactopyranoside (IPTG) induction and addition of 0.1 mmol/L CdSO4 into the culture medium, and mainly existed in cellular soluble fraction as revealed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis.	cadmium sulfate	133-138	metallothionein 3	Homo sapiens	24-29
21727445-5	2005	CdS nanoparticles were formed through a photoinduced reaction of CdSO(4) and Na(2)S(2)O(3) in an aqueous solution.	cadmium sulfate	65-72	CDP-diacylglycerol synthase 1	Homo sapiens	0-3
22767315-4	2012	Treatment with cadmium sulfate (cadmium) increased the expression of COX-2 mRNA.	cadmium sulfate	15-30	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	69-74
17538243-6	2007	Comparison with our previous DNA microarray results for 5 muM CdSO(4)-exposed HeLa cells revealed several genes that are regulated by both metals in parallel, and a gene reciprocally regulated by them.	cadmium sulfate	62-69	latexin	Homo sapiens	58-61
15049340-2	2004	In vitro, CdSO4 inhibited pure and brain AChE in concentrations higher than 0.1 mM, while it activated by approximately 70% (P<0.001) brain Na+, K+ -ATPase in concentrations up to 0.1 mM and inhibited its activity in higher concentrations.	cadmium sulfate	10-15	acetylcholinesterase	Rattus norvegicus	41-45
15049340-4	2004	A dose-response study of brain CdSO4 (1,2 and 5 mg/kg once 8 hr before decapitation) revealed a dose-dependent decrease (-14 to -30%, P<0.001) of brain AChE activity, an increase of Na+, K+ -ATPase activity (+47 to +200%, P<0.001) and an increase of Mg2+ -ATPase only after the highest dose (5mg/kg) in the short-term treatment of rats.	cadmium sulfate	31-36	acetylcholinesterase	Rattus norvegicus	155-159
14765218-1	2004	Co(II) sulfate reacts with the flexible ligand 1,4-bis(imidazol-1-ylmethyl)benzene (bix) to yield the coordination network [Co(bix)2(H2O)2](SO4).7H2O, containing polymeric ribbons of rings which penetrate and catenate a 3D single frame of the CdSO4 topology, to produce an open-channel entangled architecture with nanoporous behaviour.	cadmium sulfate	243-248	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	0-6
12686747-5	2003	CdSO(4) also inhibits MAO-A, but not MAO-B in monkey brain mitochondria.	cadmium sulfate	0-7	monoamine oxidase A	Rattus norvegicus	22-27
9733285-10	1998	Over 80% of all control or ACTH-stimulated cells were viable after incubation in the presence or absence of various CdAc2 or CdSO4 concentrations.	cadmium sulfate	125-130	pro-opiomelanocortin-alpha	Mus musculus	27-31
9733285-13	1998	Similarly, the first CdSO4 concentration to significantly inhibit basal and ACTH-stimulated steroid secretion was 10.0 microg/ml medium (39.0 micromol/L); the IC50 was 7.8 microg/ml (29.8 micromol/L).	cadmium sulfate	21-26	pro-opiomelanocortin-alpha	Mus musculus	76-80
9733285-17	1998	Based on the results from the present studies, both CdAc2 and CdSO4 appeared to incrementally inhibit control and ACTH-stimulated steroidogenesis without affecting cell viability and to be more potent inhibitors of adrenocortical cell steroid secretion than CdCl2.	cadmium sulfate	62-67	pro-opiomelanocortin-alpha	Mus musculus	114-118
11058091-4	2000	The formation of HAP bodies is part of a general cell response to stress agents, such as heat shock and cadmium sulfate, which also affect the distribution of hnRNP protein M. Electron microscopy demonstrates that in untreated cells, similar to other hnRNP proteins, HAP is associated to perichromatin fibrils.	cadmium sulfate	104-119	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	159-164
11058091-4	2000	The formation of HAP bodies is part of a general cell response to stress agents, such as heat shock and cadmium sulfate, which also affect the distribution of hnRNP protein M. Electron microscopy demonstrates that in untreated cells, similar to other hnRNP proteins, HAP is associated to perichromatin fibrils.	cadmium sulfate	104-119	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	251-256