PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9641623-4	1998	The anticoagulant activity of CMDBS was due both to direct thrombin inhibition and to catalysis of thrombin inhibition by HCII.	cmdbs	30-35	coagulation factor II, thrombin	Homo sapiens	59-67
9641623-7	1998	A kinetic study showed that all the CMDBS exhibited higher affinity for thrombin than heparin did but lower affinity than DXSu did, suggesting that the benzylamide and sulfate groups potentiate the interaction between the dextran derivatives and thrombin.	cmdbs	36-41	coagulation factor II, thrombin	Homo sapiens	246-254
9641623-4	1998	The anticoagulant activity of CMDBS was due both to direct thrombin inhibition and to catalysis of thrombin inhibition by HCII.	cmdbs	30-35	coagulation factor II, thrombin	Homo sapiens	99-107
9641623-4	1998	The anticoagulant activity of CMDBS was due both to direct thrombin inhibition and to catalysis of thrombin inhibition by HCII.	cmdbs	30-35	serpin family D member 1	Homo sapiens	122-126
9641623-7	1998	A kinetic study showed that all the CMDBS exhibited higher affinity for thrombin than heparin did but lower affinity than DXSu did, suggesting that the benzylamide and sulfate groups potentiate the interaction between the dextran derivatives and thrombin.	cmdbs	36-41	coagulation factor II, thrombin	Homo sapiens	72-80
9068899-1	1997	The kinetics of thrombin inhibition by heparin cofactor II (HC II) in the presence of dermatan sulphates, native (DS), or oversulphated (DSS 1 and DSS 2) and a biospecific dextran derivative substituted with carboxymethyl, carboxymethyl-benzylamide and carboxymethyl benzylamide-sulphonate functional groups (CMDBS), has been studied as a function of the sulphated polysaccharide concentration.	cmdbs	309-314	coagulation factor II, thrombin	Homo sapiens	16-24
9068899-9	1997	The reaction rate remained unchanged for CMDBS concentrations equal to or higher than 10(-5) M, whereas CMDBS was found to interfere strongly with the fibrinogen-thrombin interaction.	cmdbs	104-109	coagulation factor II, thrombin	Homo sapiens	162-170
9434099-1	1997	The present study demonstrates at the molecular level that dextran derivatives carboxymethyl dextran benzylamine (CMDB) and carboxymethyl dextran benzylamine sulfonate (CMDBS), characterized by a statistical distribution of anionic carboxylic groups, hydrophobic benzylamide units, and/or sulfonate moieties, interact with HIV-1 LAI gp120 and V3 consensus clades B domain.	cmdbs	169-174	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	333-338