PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 2544604-8 1989 We show here that capacitated mouse sperm, incubated with ZP glycopeptides, displayed ARs when incubated subsequently with anti-ZP3 IgG; ARs did not occur when parallel sperm samples were incubated with anti-ZP2 IgG or with anti-ZP3 Fab fragments. Glycopeptides 61-74 zona pellucida glycoprotein 3 Mus musculus 128-131 2777373-0 1989 Differences in adhesion of Pseudomonas aeruginosa to mucin glycopeptides from sputa of patients with cystic fibrosis and chronic bronchitis. Glycopeptides 59-72 LOC100508689 Homo sapiens 53-58 2589897-9 1989 The TNF activity was always higher when LPS in an amount of 10 ng/ml was added to the glycopeptides. Glycopeptides 86-99 tumor necrosis factor Mus musculus 4-7 2507289-9 1989 TRH administration in vivo normalized the Concanavalin-A binding pattern of secreted TSH glycopeptides in the PVN lesioned group but had no significant effect in the sham lesioned group. Glycopeptides 89-102 thyrotropin releasing hormone Rattus norvegicus 0-3 2552998-1 1989 Herpes simplex virus type-1 glycoprotein C (gC1) contains several O-linked oligosaccharides clustered near N-linked chains, and Pronase digestion produces glycopeptides carrying both oligosaccharide types. Glycopeptides 155-168 solute carrier family 25 member 22 Homo sapiens 44-47 2552998-3 1989 gC1 was isolated from herpes-simplex-virus-infected BHK (baby-hamster kidney) cells after short labelling periods with [3H]glucosamine, and the labelled Pronase-cleaved glycopeptides fractionated on concanavalin A-Sepharose. Glycopeptides 169-182 solute carrier family 25 member 22 Homo sapiens 0-3 2775488-0 1989 Isolation and structural characterization of sialic-acid-containing glycopeptides of the O-glycosidic type from the urine of two patients with an hereditary deficiency in alpha-N-acetylgalactosaminidase activity. Glycopeptides 68-81 alpha-N-acetylgalactosaminidase Homo sapiens 171-202 2775488-1 1989 Glycopeptides have been isolated from the urine of two patients, aged 5 and 6, with a new lysosomal storage disease characterized by a deficiency in alpha-N-acetylgalactosaminidase activity. Glycopeptides 0-13 alpha-N-acetylgalactosaminidase Homo sapiens 149-180 2544604-8 1989 We show here that capacitated mouse sperm, incubated with ZP glycopeptides, displayed ARs when incubated subsequently with anti-ZP3 IgG; ARs did not occur when parallel sperm samples were incubated with anti-ZP2 IgG or with anti-ZP3 Fab fragments. Glycopeptides 61-74 zona pellucida glycoprotein 2 Mus musculus 208-211 2544604-8 1989 We show here that capacitated mouse sperm, incubated with ZP glycopeptides, displayed ARs when incubated subsequently with anti-ZP3 IgG; ARs did not occur when parallel sperm samples were incubated with anti-ZP2 IgG or with anti-ZP3 Fab fragments. Glycopeptides 61-74 zona pellucida glycoprotein 3 Mus musculus 229-232 2544604-13 1989 Together, these findings are consistent with the hypothesis under examination, and suggest that the aggregation of sperm molecules recognized by ZP3 glycopeptides or by TPA-treated ZP is sufficient to trigger the events that occur during acrosomal exocytosis. Glycopeptides 149-162 zona pellucida glycoprotein 3 Mus musculus 145-148 2470404-2 1989 After conversion to acyl azide, the reagent reacts with the amino group of a glycopeptide, and the modified glycopeptide is deacetalized with a weak acid to unmask the aldehydo group, which is then conjugated to bovine serum albumin (BSA) by reductive alkylation with pyridine-borane. Glycopeptides 77-89 albumin Homo sapiens 219-232 2653823-5 1989 (formula; see text) This structure was verified by binding to the immobilized alpha-Gal-specific lectin, Griffonia simplicifolia I and leukoagglutinating phytohemagglutinin from Phaseolus vulgaris (L-PHA), which binds certain tri- or tetraantennary glycopeptides. Glycopeptides 249-262 glycoprotein galactosyltransferase alpha 1, 3 Mus musculus 78-87 2495036-4 1989 Fast-atom bombardment mass spectrometry analysis of G.K."s erythrocyte glycopeptides detected a series of high mannose-type oligosaccharides, which were not detected in erythrocyte N-glycans of normal cells or of other HEMPAS cases: The former contains polylactosaminoglycans and the latter contains hybrid-type oligosaccharides. Glycopeptides 71-84 SEC23 homolog B, COPII coat complex component Homo sapiens 219-225 2492959-5 1989 Proteolysis occurs near the amino- or carboxy-terminus of ZP2, producing a 23,000 Mr glycopeptide(s) that remains attached to ZP2 by intramolecular disulfide bonds. Glycopeptides 85-97 zona pellucida glycoprotein 2 Mus musculus 58-61 2492959-5 1989 Proteolysis occurs near the amino- or carboxy-terminus of ZP2, producing a 23,000 Mr glycopeptide(s) that remains attached to ZP2 by intramolecular disulfide bonds. Glycopeptides 85-97 zona pellucida glycoprotein 2 Mus musculus 126-129 2470404-2 1989 After conversion to acyl azide, the reagent reacts with the amino group of a glycopeptide, and the modified glycopeptide is deacetalized with a weak acid to unmask the aldehydo group, which is then conjugated to bovine serum albumin (BSA) by reductive alkylation with pyridine-borane. Glycopeptides 108-120 albumin Homo sapiens 219-232 2912731-7 1989 Two mechanisms of binding at the primary sites of oligomannose-type glycopeptides have been identified which account for the 3000-fold increase in affinity of a Man9 glycopeptide relative to that of methyl alpha-D-mannopyranoside. Glycopeptides 68-81 mannosidase alpha class 1A member 1 Homo sapiens 161-165 2912731-7 1989 Two mechanisms of binding at the primary sites of oligomannose-type glycopeptides have been identified which account for the 3000-fold increase in affinity of a Man9 glycopeptide relative to that of methyl alpha-D-mannopyranoside. Glycopeptides 68-80 mannosidase alpha class 1A member 1 Homo sapiens 161-165 2535484-1 1989 The N-linked oligosaccharides of cell-CAM 105, a glycoprotein involved in the intercellular adhesion between rat hepatocytes, were studied by sequential lectin-agarose affinity chromatography of desialylated, [14C]-labelled glycopeptides. Glycopeptides 224-237 CEA cell adhesion molecule 1 Rattus norvegicus 33-45 2523868-6 1989 Amino acid sequencing of glycopeptides prepared from the largest forms of L-CA indicated extensive O-linked glycosylation in at least one of the extra segments. Glycopeptides 25-38 protein tyrosine phosphatase, receptor type, C Rattus norvegicus 74-78 2562506-3 1989 The results obtained indicate that ovalbumin glycopeptides containing four to seven mannose residues and bovine lactotransferrin glycopeptides containing four to nine mannose residues were completely hydrolyzed by the enzyme. Glycopeptides 45-58 ovalbumin Bos taurus 35-44 2562506-3 1989 The results obtained indicate that ovalbumin glycopeptides containing four to seven mannose residues and bovine lactotransferrin glycopeptides containing four to nine mannose residues were completely hydrolyzed by the enzyme. Glycopeptides 129-142 lactotransferrin Bos taurus 112-128 2491877-1 1989 Antisera raised against a major 78 kD glycopeptide from pig epidermis were used to identify desmoglein II-derived glycopeptides in the conA-binding material isolated from human epidermis. Glycopeptides 38-50 CONA Sus scrofa 135-139 2491877-1 1989 Antisera raised against a major 78 kD glycopeptide from pig epidermis were used to identify desmoglein II-derived glycopeptides in the conA-binding material isolated from human epidermis. Glycopeptides 114-127 CONA Sus scrofa 135-139 3253057-8 1988 Taken together, these results demonstrate that the cloned cDNA sequence encodes a lipid-linked, PI-specific phospholipase C releasable surface isoform of N-CAM with core glycopeptide molecular weight corresponding to the authentic muscle 125 x 10(3) Mr N-CAM isoform. Glycopeptides 170-182 neural cell adhesion molecule 1 Homo sapiens 154-159 2701484-1 1989 Bronchial mucin peptide chains were obtained by performing a two-step chemical deglycosylation of the highly glycosylated regions (or glycopeptides) which are the most characteristic part of bronchial mucins. Glycopeptides 134-147 LOC100508689 Homo sapiens 10-15 2971654-3 1988 Fractionation of 32P-labeled glycopeptides followed by amino acid sequence analysis indicated that greater than 95% of the label was incorporated into two out of three glycosylation sites at Asn-82 and Asn-136 of the TGF-beta 1 precursor. Glycopeptides 29-42 transforming growth factor beta-1 proprotein Cricetulus griseus 217-227 3170547-3 1988 Upon hydrazine/nitrous acid fragmentation and radiolabeling with NaB3H4, all human unit B DEAE-resolved glycopeptide fractions yielded an acidic disaccharide which was characterized as Gal-3-SO4 beta 1----4-anhydromannitol. Glycopeptides 104-116 galectin 3 Homo sapiens 185-201 3170547-4 1988 Studies on glycopeptides modified by desialylation, desulfation, and beta-galactosidase treatment indicated that the majority (approximately 70%) of the complex carbohydrate units contain sulfate groups and that Gal-3-SO4 and sialic acid residues can coexist in terminal positions on the same N-linked oligosaccharide. Glycopeptides 11-24 galactosidase beta 1 Homo sapiens 69-87 3170547-4 1988 Studies on glycopeptides modified by desialylation, desulfation, and beta-galactosidase treatment indicated that the majority (approximately 70%) of the complex carbohydrate units contain sulfate groups and that Gal-3-SO4 and sialic acid residues can coexist in terminal positions on the same N-linked oligosaccharide. Glycopeptides 11-24 galectin 3 Homo sapiens 212-217 3211159-8 1988 The binding of SAP to ligand(s) in zymosan extract or ovalbumin was inhibited by the preincubation of SAP with either zymosan extract or ovalbumin glycopeptides, both of which share similar mannose oligosaccharide sequences. Glycopeptides 147-160 amyloid P component, serum Homo sapiens 15-18 3211159-8 1988 The binding of SAP to ligand(s) in zymosan extract or ovalbumin was inhibited by the preincubation of SAP with either zymosan extract or ovalbumin glycopeptides, both of which share similar mannose oligosaccharide sequences. Glycopeptides 147-160 amyloid P component, serum Homo sapiens 102-105 3377767-5 1988 In the present study, equimolar mixtures of two oligomannose type glycopeptides, a Man-6 and a Man-9 glycopeptide, gives a quantitative precipitation profile which shows two protein peaks. Glycopeptides 66-79 mannosidase alpha class 1A member 1 Homo sapiens 95-100 2971395-0 1988 Oligosaccharide structure and amino acid sequence of the major glycopeptides of mature human beta-hexosaminidase. Glycopeptides 63-76 O-GlcNAcase Homo sapiens 93-112 3402460-6 1988 The glycopeptides of AGP-A did not bind to ConA-Sepharose whereas for AGP-B and AGP-C 18% and 44%, respectively, of the glycopeptides were bound as diantennary structures. Glycopeptides 4-17 orosomucoid 1 Homo sapiens 21-26 2453314-3 1988 Reduction of the mucin decreased the reactivity by only 14% indicating that the assay reacts almost as well with mucin glycopeptides as with native mucin. Glycopeptides 119-132 LOC100508689 Homo sapiens 17-22 2453314-3 1988 Reduction of the mucin decreased the reactivity by only 14% indicating that the assay reacts almost as well with mucin glycopeptides as with native mucin. Glycopeptides 119-132 LOC100508689 Homo sapiens 113-118 2453314-3 1988 Reduction of the mucin decreased the reactivity by only 14% indicating that the assay reacts almost as well with mucin glycopeptides as with native mucin. Glycopeptides 119-132 LOC100508689 Homo sapiens 113-118 3298096-1 1987 Two glycopeptides associating the aminoacid sequence of LH-RH with MDP were prepared, using a Lys residue as a linker. Glycopeptides 4-17 gonadotropin releasing hormone 1 Homo sapiens 56-61 3367907-3 1988 Selection of this carbohydrate-containing form of NB with Datura stramonium lectin, its susceptibility to digestion by endo-beta-galactosidase, and determination of the size of NBp glycopeptides by gel filtration chromatography suggested that the increase in molecular weight is due to processing to polylactosaminoglycan. Glycopeptides 181-194 NUBP iron-sulfur cluster assembly factor 1, cytosolic Homo sapiens 177-180 3365364-1 1988 We have recently demonstrated that certain oligomannose and bisected hybrid type glycopeptides and bisected complex type oligosaccharides are bivalent for binding to concanavalin A and can precipitate the lectin [Bhattacharyya, L., Ceccarini, C., Lorenzoni, P., & Brewer, C.F. Glycopeptides 81-94 LOW QUALITY PROTEIN: lectin Glycine max 205-211 2825412-9 1987 In addition to these disaccharides, Pronase-resistant PNA-binding glycopeptides of gC-1 also contained neutral trisaccharides. Glycopeptides 66-79 solute carrier family 25 member 22 Homo sapiens 83-87 3117549-8 1987 259, 6586-6592], the endo-beta-galactosidase of Bacteroides fragilis cannot hydrolyse branch-point beta-galactosidic linkages on erythrocyte membrane glycopeptides. Glycopeptides 150-163 galactosidase beta 1 Homo sapiens 26-44 2444130-8 1987 Glycoasparagine, lacking all amino acids except the carbohydrate-linking asparagine, inhibits IgE-binding to glycopeptide discs up to 100%. Glycopeptides 109-121 immunoglobulin heavy constant epsilon Homo sapiens 94-97 3620357-0 1987 Glycolipids and glycopeptides of red cell membranes in congenital dyserythropoietic anaemia type II (CDA II). Glycopeptides 16-29 SEC23 homolog B, COPII coat complex component Homo sapiens 55-99 3597368-1 1987 Immobilized tomato lectin interacts with high affinity with glycopeptides containing long poly-N-acetyllactosamine chains. Glycopeptides 60-73 LTL Solanum lycopersicum 19-25 3311021-13 1987 Thus the 118,000-Mr component is an integral part of the mucin and, although linked to large glycopeptides by disulphide bonds, this component also has proteinase-sensitive peptide bonds, presumably at terminal locations such that brief treatment with proteinases releases the molecule in a reasonably intact form. Glycopeptides 93-106 solute carrier family 13 member 2 Rattus norvegicus 57-62 3104329-8 1987 TRH caused a 2-fold increase in secretion of [3H]mannose-labeled TSH glycopeptides due almost exclusively to a specific increase in structures that bound to ConA-Sepharose and eluted with 10mM alpha-methylglucoside, corresponding to biantennary complex or unusual hybrid species. Glycopeptides 69-82 thyrotropin releasing hormone Mus musculus 0-3 3104329-11 1987 Moreover, ConA-Sepharose chromatography of secreted [3H]glucosamine- and [3H]fucose-labeled TSH glycopeptides showed similar increases in ConA-Sepharose binding with TRH as noted with [3H]mannose labeling. Glycopeptides 96-109 thyrotropin releasing hormone Mus musculus 166-169 3128279-1 1988 of oligosaccharides of N-acetyl-lactosamine-type released from human erythrocyte glycopeptides by endo-beta-galactosidase. Glycopeptides 81-94 galactosidase beta 1 Homo sapiens 103-121 2453447-7 1988 The hemagglutinating activity of antibody 177.1 is inhibited by purified glycophorin A and its chymotryptic glycopeptides CH1 (amino acid residues 1-64) and CH3 (amino acid residues 35-64), whereas the hemagglutinating activity of 179.3 is inhibited weakly by glycophorin A but not by chymotryptic peptides. Glycopeptides 108-121 SUN domain containing ossification factor Homo sapiens 122-125 2453447-7 1988 The hemagglutinating activity of antibody 177.1 is inhibited by purified glycophorin A and its chymotryptic glycopeptides CH1 (amino acid residues 1-64) and CH3 (amino acid residues 35-64), whereas the hemagglutinating activity of 179.3 is inhibited weakly by glycophorin A but not by chymotryptic peptides. Glycopeptides 108-121 glycophorin A (MNS blood group) Homo sapiens 260-273 3055253-14 1988 High-performance ion exchange chromatography revealed mucin glycopeptides to constitute a very heterogeneous population. Glycopeptides 60-73 LOC100508689 Homo sapiens 54-59 3426806-5 1987 The Ge2 epitopes were found to be located on a tryptic glycopeptide from glycophorin D comprising about 20-30 amino-acid residues. Glycopeptides 55-67 glycophorin C (Gerbich blood group) Homo sapiens 73-86 3435657-8 1987 Some of the changes in glycopeptides were interpreted in terms of the levels of the major components of the matrix such as the interstitial procollagens and fibronectin. Glycopeptides 23-36 fibronectin 1 Bos taurus 157-168 3621238-0 1987 Application of the trichloroacetimidate method to the synthesis of glycopeptides of the mucin type containing a beta-D-Galp-(1----3)-D-GalpNAc unit. Glycopeptides 67-80 LOC100508689 Homo sapiens 88-93 3621238-0 1987 Application of the trichloroacetimidate method to the synthesis of glycopeptides of the mucin type containing a beta-D-Galp-(1----3)-D-GalpNAc unit. Glycopeptides 67-80 galanin like peptide Homo sapiens 119-123 3789744-1 1986 Mannose-labeled epiglycanin was prepared by incubation of TA3-Ha ascites cells with [2-3H]mannose, removal of the epiglycanin by incubation of viable cells with L-1-p-tosylamino-2-phenylethyl chloromethyl ketone-trypsin, and isolation of the large epiglycanin glycopeptides by gel filtration. Glycopeptides 260-273 mucin 21 Mus musculus 16-27 3593280-5 1987 Lectin-binding glycopeptides were eluted with appropriate competing sugars and further analysed by gel filtration, base/borohydride elimination and susceptibility to degradation by glycosidases including endo-beta-galactosidase. Glycopeptides 15-28 galactosidase, beta 1 Mus musculus 209-227 3593280-6 1987 Abundant quantities of N-linked polylactosamine-type glycopeptides, which bound only to the WGA columns, were identified on mature granulocytes but the molecules were highly-branched (i.e. resistant to endo-beta-galactosidase). Glycopeptides 53-66 galactosidase, beta 1 Mus musculus 207-225 3566706-1 1987 The four major isoelectric forms of human liver neuraminidase (with pI values between 3.4 and 4.8) have been isolated by preparative isoelectric focusing and characterized with regard to their substrate specificity using glycoprotein, glycopeptide, oligosaccharide and ganglioside natural substrates. Glycopeptides 235-247 neuraminidase 1 Homo sapiens 48-61 3789744-2 1986 Purification of epiglycanin glycopeptides was performed by wheat germ agglutinin affinity chromatography. Glycopeptides 28-41 mucin 21 Mus musculus 16-27 2428831-5 1986 Glycopeptides bearing the antigenic determinant were identified by their ability to block binding of M-proteins and HNK-1 antibodies to MAG-coated microwells by enzyme-linked immunosorbent assay (ELISA). Glycopeptides 0-13 beta-1,3-glucuronyltransferase 1 Homo sapiens 116-121 2944883-1 1986 The fibronectin receptor is a complex of two cell surface glycopeptides that mediate the binding of cells to fibronectin substrata. Glycopeptides 58-71 fibronectin 1 Homo sapiens 4-15 2944883-1 1986 The fibronectin receptor is a complex of two cell surface glycopeptides that mediate the binding of cells to fibronectin substrata. Glycopeptides 58-71 fibronectin 1 Homo sapiens 109-120 2428831-5 1986 Glycopeptides bearing the antigenic determinant were identified by their ability to block binding of M-proteins and HNK-1 antibodies to MAG-coated microwells by enzyme-linked immunosorbent assay (ELISA). Glycopeptides 0-13 myelin associated glycoprotein Homo sapiens 136-139 2578862-3 1985 alpha 2 M is bound to a low molecular weight glycopeptide, which is released during trypsinization of alpha 2 M. Glycopeptides 45-57 alpha-2-macroglobulin Rattus norvegicus 0-9 3709931-2 1986 Nearly 90% of glycopeptides released from amniotic fluid fibronectin was not bound by concanavalin A-Sepharose, whereas 75% of glycopeptides from plasma fibronectin was bound. Glycopeptides 14-27 fibronectin 1 Homo sapiens 57-68 4043085-3 1985 Glycopeptides liberated from apolipoprotein-B by pronase were fractionated by affinity chromatography on concanavalin-A--Sepharose. Glycopeptides 0-13 apolipoprotein B Homo sapiens 29-45 3920213-8 1985 Removal of polylactosamine sequences from the former glycopeptide by endo-beta-galactosidase digestion caused the elution peak for this fraction to change from 2.0 to 2.5 M, the same as for the complex N-linked carbohydrate-containing glycopeptide. Glycopeptides 53-65 galactosidase beta 1 Homo sapiens 74-92 16664119-13 1985 The smaller glycopeptides (IV, V, VI) were partially susceptible to alpha-mannosidase digestion, but this enzyme did not release any radioactive mannose from the larger-sized glycopeptides. Glycopeptides 12-25 alpha-mannosidase At3g26720 Glycine max 68-85 3967951-4 1985 Neuraminidase treatment of the glycopeptides indicates that only gp87 contains accessible sialic acid moieties. Glycopeptides 31-44 neuraminidase 1 Homo sapiens 0-13 3749029-4 1986 In addition, a quantitative reduction of glycopeptides was observed in mutant livers, when the radioactive peaks from the Bio-Gel P-6 fractionation were pooled and analyzed on a Dowex 50 column, followed by separation on DE-52 columns. Glycopeptides 41-54 exosome component 9 Mus musculus 130-133 3768895-8 1986 Unlike the biantennary glycopeptides of human plasma fibronectin, those from skin fibroblast fibronectin were core-fucosylated and less highly sialylated. Glycopeptides 23-36 fibronectin 1 Homo sapiens 53-64 3755358-1 1986 Endo-beta-galactosidase treatment of glycopeptides derived from the trypsinate and membranes of PC12 pheochromocytoma cells and cultured sympathetic neurons demonstrated the presence of poly(N-acetyllactosaminyl) units on tri- and tetraantennary oligosaccharides, some of which have a core fucose residue and a 2,6-substituted alpha-linked mannose residue. Glycopeptides 37-50 galactosidase, beta 1 Rattus norvegicus 5-23 3514617-12 1986 In contrast, the N Sta glycophorin yielded two CNBr glycopeptides B; both contained fewer amino acid residues and virtually lacked Man and GlcNAc, indicating the absence of the Asn-linked carbohydrate. Glycopeptides 52-65 GCY Homo sapiens 19-22 3088498-7 1986 Treatment with exo-beta-galactosidase transformed the trisaccharide OS II into the disaccharide OS I, indicating that the deficiency of beta-galactosidase in GM1 gangliosidosis type I, but not in type II, also affects glycoprotein catabolism, leading to the accumulation of glycopeptides containing terminal beta-galactosyl residues and N-acetyllactosamine repeating units. Glycopeptides 274-287 galactosidase beta 1 Homo sapiens 19-37 3527818-3 1986 Muramyl peptides (MDP) are synthetic glycopeptides which can substitute mycobacteria in FCA and are also adjuvant-active in saline. Glycopeptides 37-50 dipeptidase 1 Homo sapiens 18-21 3972840-11 1985 Uptake was inhibited by yeast mannan and by glycopeptides isolated from either ovalbumin or uteroferrin. Glycopeptides 44-57 acid phosphatase 5, tartrate resistant Sus scrofa 92-103 2859851-3 1985 Glycopeptides were prepared from Thy-1 obtained from cells labelled by periodate/boro[3H]hydride treatment. Glycopeptides 0-13 thymus cell antigen 1, theta Mus musculus 33-38 3966805-1 1985 Using Sephadex G-75 and DEAE-cellulose column chromatography, an 8270-Da glycopeptide (designated Fragment II) has been isolated from a cyanogen bromide-formic acid digest of a heat-stable factor from Gaucher spleen which activates a lipid-depleted preparation of lysosomal glucocerebrosidase from human liver. Glycopeptides 73-85 glucosylceramidase beta Rattus norvegicus 274-292 2578862-3 1985 alpha 2 M is bound to a low molecular weight glycopeptide, which is released during trypsinization of alpha 2 M. Glycopeptides 45-57 alpha-2-macroglobulin Rattus norvegicus 102-111 6332144-1 1984 In the present study, well-defined immunomodulatory synthetic glycopeptides were used to investigate putative regulatory mechanisms of in vitro IL 2 production by normal human peripheral blood mononuclear cells. Glycopeptides 62-75 interleukin 2 Homo sapiens 144-148 2412908-1 1985 Trypsin digestion of haptoglobin beta (heavy) chain resulted in five glycopeptides. Glycopeptides 69-82 haptoglobin Homo sapiens 21-32 6529554-1 1984 Sialylated biantennary glycopeptides from human fibrinogen were analyzed with fast atom bombardment mass spectrometry. Glycopeptides 23-36 fibrinogen beta chain Homo sapiens 48-58 3968538-6 1985 GP59(E1) contained glycopeptides in two size classes, designated R1.5 and R2.1; E1 contained these and an additional size class, R2.7. Glycopeptides 19-32 small nucleolar RNA, H/ACA box 73A Homo sapiens 0-8 3968538-7 1985 GP43(E2) contained glycopeptides in three size classes, R1.5, R2.1 and R2.7; E2 contained these and size class R3.3. Glycopeptides 19-32 cystatin 12, pseudogene Homo sapiens 0-8 3931095-3 1985 A minimum of four (possibly five) concanavalin A-binding glycopeptides was generated by cyanogen bromide cleavage of IRBP. Glycopeptides 57-70 retinol binding protein 3 Bos taurus 117-121 6433980-5 1984 Glycopeptides from fetal plasma fibronectin contained a population of glycopeptides which bound to both lectin gels. Glycopeptides 70-83 fibronectin 1 Homo sapiens 32-43 6433980-7 1984 In contrast, glycopeptides from adult plasma fibronectin practically lacked such glycopeptides. Glycopeptides 13-26 fibronectin 1 Homo sapiens 45-56 6433980-8 1984 Another difference observed was that fetal plasma fibronectin had a larger amount of concanavalin A-unbound glycopeptides than did adult plasma fibronectin. Glycopeptides 108-121 fibronectin 1 Homo sapiens 50-61 6436230-4 1984 The non- or low-reactivity of placenta fibronectin with this lectin was also demonstrated by affinity chromatography with concanavalin A-agarose, in which more than 90% of the radiolabeled glycopeptides derived from placenta fibronectin was not retained on the gel. Glycopeptides 189-202 fibronectin 1 Homo sapiens 39-50 6094178-7 1984 A proportion of [3H]fucose-labelled glycopeptides was susceptible to endo-beta-galactosidase, confirming the immunoblotting experiment using antibodies against the Lea and the difucosylated Type 2 antigenic determinants. Glycopeptides 36-49 galactosidase beta 1 Homo sapiens 74-92 6736034-2 1984 The glycopeptides were digested by endo-beta-galactosidase under various conditions and oligosaccharides and core glycopeptides thus obtained and intact glycopeptides were analyzed by methylation, exoglycosidase digestion, and fast atom bombardment mass spectrometry. Glycopeptides 4-17 galactosidase beta 1 Homo sapiens 40-58 6203920-3 1984 The chemically defined immunoadjuvant glycopeptide, N-acetyl-muramyl-L-alanyl-D-isoglutamine (MDPL) also promoted an increase in ODC activity at 2 hours that was maximal after 4 hours, while little or no effect was observed with the D-alanyl analog (MDPD) that is devoid of adjuvant activity. Glycopeptides 38-50 ornithine decarboxylase, structural 1 Mus musculus 129-132 6610106-4 1984 The results show that the three disulfide-linked polypeptides of Lyt-2/3 molecules are all surface-expressed glycopeptides possessing hydrophobic regions residing within the lipid bilayer. Glycopeptides 109-122 CD8 antigen, alpha chain Mus musculus 65-72 6725252-3 1984 As described in this report, the latter lectin binds glycopeptides that contain either the repeating N-acetyllactosamine sequence or an outer mannose residue substituted at C-2 and C-6 by N-acetyllactosamine. Glycopeptides 53-66 complement component 2 (within H-2S) Mus musculus 173-176 6725252-3 1984 As described in this report, the latter lectin binds glycopeptides that contain either the repeating N-acetyllactosamine sequence or an outer mannose residue substituted at C-2 and C-6 by N-acetyllactosamine. Glycopeptides 53-66 complement component 6 Mus musculus 181-184 6230110-3 1984 The N-acetylglucosaminyltransferases I and II (enzymes which attach N-acetylglucosamine to either the 3" or 6" core mannose, respectively) were assayed with structurally-defined glycopeptides as specific acceptors and galactosyltransferase was assayed with asialo, agalactosylfetuin (galactose is attached to exposed N-acetylglucosamine termini). Glycopeptides 178-191 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Rattus norvegicus 4-45 6704415-8 1984 These high molecular weight 3H-labeled glycopeptides were degraded with endo-beta-galactosidase but not with testicular hyaluronidase. Glycopeptides 39-52 galactosidase beta 1 Homo sapiens 77-95 6199836-0 1984 A common epitope identified by a monoclonal antibody, MID 2, present on all leucocytes and associated with a group of high molecular weight glycopeptides. Glycopeptides 140-153 midline 2 Homo sapiens 54-59 6199017-9 1984 Therefore the antibody to human small-intestinal mucin appears to recognize a "naked" (non-glycosylated and Pronase-susceptible) peptide region(s) of mucin glycopeptides. Glycopeptides 156-169 LOC100508689 Homo sapiens 49-54 6199017-9 1984 Therefore the antibody to human small-intestinal mucin appears to recognize a "naked" (non-glycosylated and Pronase-susceptible) peptide region(s) of mucin glycopeptides. Glycopeptides 156-169 LOC100508689 Homo sapiens 150-155 6232267-4 1984 Linkage region-enriched glycopeptides, prepared by endo-beta-galactosidase digestion of the peptidokeratan sulfates, behaved similarly to the peptidokeratan sulfates on the same affinity chromatography. Glycopeptides 24-37 galactosidase beta 1 Bos taurus 56-74 6086072-1 1984 The specificity of a human anti-Mg antibody has been evaluated by agglutination-inhibition assays using several peptides and glycopeptides structurally related to the N-terminal end of glycophorin A, which were obtained by chemical synthesis. Glycopeptides 125-138 glycophorin A (MNS blood group) Homo sapiens 185-198 6626573-2 1983 The 1H-NMR chemical shifts of the previously assigned anomeric and H-2 protons from the peripheral residues of the glycopeptide are identical to the corresponding values for the reduced oligosaccharide. Glycopeptides 115-127 relaxin 2 Homo sapiens 67-70 6667476-0 1983 13C-N.m.r.-spectral study of the mode of binding of Gd3+ to various glycopeptides. Glycopeptides 68-81 GRDX Homo sapiens 52-55 6667476-4 1983 When the amino and carboxyl groups of the amino acid are blocked, noticeable interaction of Gd3+ with the glycosidic oxygen atom (O-3) and O-2" for the glycopeptide containing alpha-D-Galp, and with O-3 and N-2" for the glycopeptide containing alpha-D-GalpNAc, is observed. Glycopeptides 152-164 GRDX Homo sapiens 92-95 6667476-4 1983 When the amino and carboxyl groups of the amino acid are blocked, noticeable interaction of Gd3+ with the glycosidic oxygen atom (O-3) and O-2" for the glycopeptide containing alpha-D-Galp, and with O-3 and N-2" for the glycopeptide containing alpha-D-GalpNAc, is observed. Glycopeptides 220-232 GRDX Homo sapiens 92-95 6418744-3 1983 The first mentioned oligosaccharide, which was released in a steady and slow process unaffected by the addition of EDTA, appeared to be primarily the product of endo-beta-N-acetylglucosaminidase action on newly synthesized glycoprotein and such an enzyme with a neutral pH optimum capable of hydrolyzing exogenous glycopeptides and oligosaccharides (Km = 18 microM) was found in the thyroid microsomal fraction. Glycopeptides 314-327 O-GlcNAcase Homo sapiens 166-194 6225773-5 1983 GP-A was then serially digested with exoglycosidases, and the released sugars and the composition of the residual glycopeptides isolated by gel filtration were analyzed by gas-liquid chromatography. Glycopeptides 114-127 glycophorin-A Bos taurus 0-4 6870863-3 1983 Simultaneously, there occur increases in the bindings of 125I-labeled soybean lectin and 125I-Ricinus communis toxin to unsubstituted sites in glycopeptides. Glycopeptides 143-156 LOW QUALITY PROTEIN: lectin Glycine max 78-84 6629141-0 1983 Dermatan sulphate and mucin glycopeptides from the human uterine cervix. Glycopeptides 28-41 LOC100508689 Homo sapiens 22-27 6831431-2 1983 When mouse LM-22 cells (nonmalignant and devoid of gangliosides) were preincubated with GM1 ganglioside (3.0 micrograms/ml), the cell surface glycopeptide inhibitor effectively arrested cell division. Glycopeptides 142-154 coenzyme Q10A Mus musculus 88-91 6870830-7 1983 When the bound glycopeptides were chromatographed on Bio-Gel P-6, it was found that confluent cells contained a larger proportion of lower-molecular-weight glycopeptides than subconfluent cells. Glycopeptides 15-28 S100 calcium binding protein A12 Homo sapiens 61-64 6229300-4 1983 GPI consists of two glycopeptides, an alpha and a beta chain connected by a disulphide bridge. Glycopeptides 20-33 glucose-6-phosphate isomerase Homo sapiens 0-3 6345185-3 1983 The carbohydrate groups present in the glycopeptide cleaved from purified [3H]-GlcNAc-rhodopsin by an enzyme from the retinal pigment epithelium were analyzed in terms of the size of the oligosaccharide chains, the sequence of the sugars and their anomeric linkages. Glycopeptides 39-51 rhodopsin Homo sapiens 86-95 6174521-2 1982 Glycopeptides and oligosaccharides were prepared from alpha-fetoprotein by protease treatment and hydrazinolysis, respectively, and subjected to carbohydrate and amino acid analysis. Glycopeptides 0-13 alpha fetoprotein Homo sapiens 54-71 6832456-4 1983 Addition of soybean trypsin inhibitor (SbTI) blocks almost completely the release of glycopeptides but not the vesiculation. Glycopeptides 85-98 kunitz trypsin protease inhibitor Glycine max 20-37 6284780-10 1982 Paper electrophoresis of [3H]glucosamine-labeled tryptic glycopeptides reveals at least three radioactive peaks, suggesting that the two known glycosylation sites in human POMC may be variably glycosylated. Glycopeptides 57-70 proopiomelanocortin Homo sapiens 172-176 7107587-12 1982 Affinity chromatography of the glycopeptides on concanavalin A-Sepharose also showed that the glycopeptides from fibrinogen are greater than 95% biantennary oligosaccharide chains. Glycopeptides 31-44 fibrinogen beta chain Homo sapiens 113-123 7107587-12 1982 Affinity chromatography of the glycopeptides on concanavalin A-Sepharose also showed that the glycopeptides from fibrinogen are greater than 95% biantennary oligosaccharide chains. Glycopeptides 94-107 fibrinogen beta chain Homo sapiens 113-123 7115737-1 1982 Pronase digestion of human transcortin yielded two major glycopeptides (GID3 and G2D2, in a molar ratio of approx. Glycopeptides 57-70 serpin family A member 6 Homo sapiens 27-38 7093235-2 1982 The array of glycopeptides from cellular E1 and E2 appeared similar to the glycopeptides (S1, S2, S3, and S4) found in mature virus glycoproteins described previously [Hakimi, J., & Atkinson, P. H. (1980) Biochemistry 19, 5619]. Glycopeptides 13-26 small nucleolar RNA, H/ACA box 73A Homo sapiens 41-50 7093235-6 1982 By contrast, the products of PE2 cleavage (E2 and E3) contained sialyl glycopeptides similar to those found in mature virus (S1, S2, and S3). Glycopeptides 71-84 ETS2 repressor factor Homo sapiens 29-32 7093235-6 1982 By contrast, the products of PE2 cleavage (E2 and E3) contained sialyl glycopeptides similar to those found in mature virus (S1, S2, and S3). Glycopeptides 71-84 cystatin 12, pseudogene Homo sapiens 43-52 6948606-8 1982 High-molecular-weight glycopeptides predominated on another human myeloid leukemia cell line KG1, but they were expressed at low levels on both a human monocytic leukemia cel line (THP-1) and a human T-lymphoblastoid cell line (Jurkat). Glycopeptides 22-35 GLI family zinc finger 2 Homo sapiens 181-186 6896906-5 1982 Zn-alpha2-glycoprotein is the only plasma protein which has a common determinant with nephritogenic urinary glycoprotein or glycopeptides. Glycopeptides 124-137 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 0-22 6184028-5 1982 Antigens of H-2 system were detected in fraction IV, which contained three glycopeptides of molecular weights 18000, 37000 and 48000 and isoelectric points 6.0, 5.8, and 6.7 respectively. Glycopeptides 75-88 relaxin 2 Homo sapiens 12-15 7325959-6 1981 Glycopeptides from soya-bean (Glycine max) lectin and fetuin are also strong inhibitors of Datura lectin, indicating that it interacts with internal N-acetylglucosamine residues. Glycopeptides 0-13 LOW QUALITY PROTEIN: lectin Glycine max 43-49 7317384-5 1981 Spectra of two endo-beta-N-acetylglucosaminidase products of the S4 glycopeptides are reported. Glycopeptides 68-81 O-GlcNAcase Homo sapiens 20-48 7325959-6 1981 Glycopeptides from soya-bean (Glycine max) lectin and fetuin are also strong inhibitors of Datura lectin, indicating that it interacts with internal N-acetylglucosamine residues. Glycopeptides 0-13 LOW QUALITY PROTEIN: lectin Glycine max 98-104 7325959-8 1981 After prolonged proteolytic digestion of reduced and S-carboxymethylated or S-aminoethylated derivatives of the lectin, glycopeptides of mol.wt. Glycopeptides 120-133 LOW QUALITY PROTEIN: lectin Glycine max 112-118 7284304-0 1981 Demonstration of heterogeneity of chick ovalbumin glycopeptides using 360-MHz proton magnetic resonance spectroscopy. Glycopeptides 50-63 ovalbumin (SERPINB14) Gallus gallus 40-49 7407676-4 1980 The PA 1 cells contained also oligomannosyl type glycans, presumably linked to asparagine (fraction C glycopeptides). Glycopeptides 102-115 PAXIP1 associated glutamate rich protein 1 Homo sapiens 4-8 6158338-1 1980 Human follicle-stimulating hormone (human FSH), dansylated human FSH, human FSH-alpha and human FSH-beta subunits were individually conjugated by photoactivation to an azidobenzoyl derivative of a glycopeptide isolated from fetuin. Glycopeptides 197-209 glycoprotein hormones, alpha polypeptide Homo sapiens 76-85 6158338-1 1980 Human follicle-stimulating hormone (human FSH), dansylated human FSH, human FSH-alpha and human FSH-beta subunits were individually conjugated by photoactivation to an azidobenzoyl derivative of a glycopeptide isolated from fetuin. Glycopeptides 197-209 follicle stimulating hormone subunit beta Homo sapiens 96-104 6771264-3 1980 Fibronectin isolated from chick embryo fibroblasts binds both hyaluronic acid and heparin; heparan sulfate is bound less efficiently, and chondroitin sulfate and glycopeptides are bound minimally. Glycopeptides 162-175 fibronectin 1 Gallus gallus 0-11 7358339-3 1980 The Ss blood group antigen determinants were found to be associated with the N-terminal tryptic and chymotryptic glycopeptides (residues 1--35 or 1--32) of the Ss sialoglycoprotein from human erythrocyte membranes. Glycopeptides 113-126 glycophorin B (MNS blood group) Homo sapiens 4-18 7378456-0 1980 Amino acid sequence, location and phylogenetic aspects of the glycopeptides of human lactotransferrin. Glycopeptides 62-75 lactotransferrin Homo sapiens 85-101 6772538-1 1980 The N-terminal amino acid sequence (residues 1--35) of the Ss sialoglycoprotein (or glycophorin B) from human erythrocyte membranes of defined Ss blood group activity was determined by manual sequencing methods, using N-terminal tryptic or chymotryptic glycopeptides and various secondary peptides. Glycopeptides 253-266 glycophorin B (MNS blood group) Homo sapiens 84-97 379005-4 1979 Cyanogen bromide cleavage of glycophorin A from red cells and the K562 cell protein gives apparently identical fragments, and the glycopeptides and oligosaccharides obtained after Pronase and mild alkaline treatment are closely similar. Glycopeptides 130-143 glycophorin A (MNS blood group) Homo sapiens 29-42 518544-0 1979 Bi-and tri-antennary human transferrin glycopeptides and their affinities for the hepatic lectin specific for asialo-glycoproteins. Glycopeptides 39-52 transferrin Homo sapiens 27-38 220199-6 1979 It proved possible to distinguish several categories of hematopoietic cell lines due to the effect that pretreatment of the glycopeptides with neuraminidase or mild acid exerted on their subsequent chromatographic behavior. Glycopeptides 124-137 neuraminidase 1 Homo sapiens 143-156 227363-0 1979 Neuraminidase inhibition by chemically sulphated glycopeptides. Glycopeptides 49-62 neuraminidase 1 Bos taurus 0-13 227363-1 1979 Chemically sulphated glycopeptides (derived from pig duodenal mucosa) inhibited Clostridium perfringens neuraminidase (EC 3.2.1.18) activity in a pH-dependent manner. Glycopeptides 21-34 neuraminidase 1 Bos taurus 104-117 438217-3 1979 One of the prominent features common to all these glycopeptides was that they all contain 1 fucosyl residue at either C-3 or C-6 position of the N-acetylglucosamine which is linked to asparagine. Glycopeptides 50-63 complement C3 Homo sapiens 118-121 438217-3 1979 One of the prominent features common to all these glycopeptides was that they all contain 1 fucosyl residue at either C-3 or C-6 position of the N-acetylglucosamine which is linked to asparagine. Glycopeptides 50-63 complement C6 Homo sapiens 125-128 99447-0 1978 Preparation of glycopeptides and oligosaccharides from thyroxine-binding globulin. Glycopeptides 15-28 serpin family A member 7 Homo sapiens 55-81 668697-3 1978 By correlation of these spectra and comparison with spectra of reference glycopeptides and sialyl-lactose isomers it was possible to assign all signals belonging to anomeric, mannose H-2, sialic acid H-3 and N-acetyl protons. Glycopeptides 73-86 H3 clustered histone 14 Homo sapiens 200-203 99447-10 1978 We propose that TBG contains four oligosaccharide chains as calculated from the molecular weights of the glycopeptides and from compositional data assuming 1 asparagine residue/glycopeptide. Glycopeptides 105-117 serpin family A member 7 Homo sapiens 16-19 99447-11 1978 The carbohydrate structures of the glycopeptides and relative affinities of TBG, glycopeptides and oligosaccharides for hepatocyte plasma membrane binding are presented in the accompanying paper (Zinn, A.B., Marshall, J.S., and Carlson, D.M. Glycopeptides 35-48 serpin family A member 7 Homo sapiens 76-79 308510-0 1978 Studies on the attachment of N-acetylneuraminic acid to glycopeptides from alpha-1-antitrypsin. Glycopeptides 56-69 serpin family A member 1 Homo sapiens 75-94 687592-0 1978 Structural studies on rabbit transferrin: isolation and characterization of the glycopeptides. Glycopeptides 80-93 serotransferrin Oryctolagus cuniculus 29-40 687592-2 1978 The composition and molecular weight of the Pronase glycopeptides revealed that rabbit transferrin contains two heteropolysaccharide units, each composed of 2 sialic acid residues, 2 galactose residues, 3 mannose residues, and 4-N-acetylglucosamine residues. Glycopeptides 52-65 serotransferrin Oryctolagus cuniculus 87-98 668707-6 1978 Treatment with neuraminidase or acetylation of amino groups destroyed the M and N blood-group activity and increased the activity towards Vicia graminea anti-N lectin of all glycopeptides studied. Glycopeptides 174-187 neuraminidase 1 Homo sapiens 15-28 75805-3 1977 Glycopeptides, obtained by excessive pronase treatment of fetuin were partially capable of replacing the nonhydrolyzed fetuin. Glycopeptides 0-13 alpha-2-HS-glycoprotein Ovis aries 58-64 659387-0 1978 Glycopeptides isolated from ovine submaxillary mucin. Glycopeptides 0-13 LOC100508689 Homo sapiens 47-52 620075-1 1978 The carbohydrate-binding specificity of two pokeweed (Phytolacca americana) mitogens (Pa-1 and Pa-2) was investigated by means of hemagglutination inhibition assays and the quantitative inhibition of the binding of 125I-labeled lectins to human erythrocytes using various oligosaccharides, glycopeptides and glycoproteins as hapten inhibitors. Glycopeptides 290-303 PAXIP1 associated glutamate rich protein 1 Homo sapiens 86-99 75805-3 1977 Glycopeptides, obtained by excessive pronase treatment of fetuin were partially capable of replacing the nonhydrolyzed fetuin. Glycopeptides 0-13 alpha-2-HS-glycoprotein Ovis aries 119-125 852928-1 1977 A relatively easy synthetic method is reported for the production of the immunoadjuvant glycopeptide, N-acetyl-muramy-L-alanyl-D-isoglutamine (MDP). Glycopeptides 88-100 dipeptidase 1 Homo sapiens 143-146 849453-3 1977 The glycopeptide fraction from alpha1-acid glycoprotein is complex (i.e., the carbohydrate moiety contains mannose, galactose, N-acetylglucosamine, and sailic acid), as is one of the glycopeptide fractions from thyroglobulin (type I). Glycopeptides 4-16 thyroglobulin Homo sapiens 211-224 986187-1 1976 Approximately 70% of fucose-labeled glycopeptides from the cell surface and cellular material of rat fibroblasts (3Y1B cells) were hydrolyzed by endo-beta-N-acetylglucosaminidase D in the presence of neuraminidase, beta-galactosidase and beta-N-acetylglucosaminidase. Glycopeptides 36-49 galactosidase, beta 1 Rattus norvegicus 215-233 795426-2 1976 The relevant glycopeptides were isolated from tryptic hydrolysates of the glycosylated ribonuclease and analysed. Glycopeptides 13-26 ribonuclease Saccharomyces cerevisiae S288C 87-99 978772-5 1976 Based on analogy with other cell membranes, a schema is given for the structure of the membrane glycopeptides on the neuroblastoma cell. Glycopeptides 96-109 Rho guanine nucleotide exchange factor (GEF) 16 Mus musculus 117-130 986187-2 1976 Structure of the susceptible glycopeptides were found to be very similar to non-membrane glycopeptides of the complex heteropolysaccharide unit, such as the sialylated glycopeptides of thyroglobulin. Glycopeptides 29-42 thyroglobulin Rattus norvegicus 185-198 986187-2 1976 Structure of the susceptible glycopeptides were found to be very similar to non-membrane glycopeptides of the complex heteropolysaccharide unit, such as the sialylated glycopeptides of thyroglobulin. Glycopeptides 89-102 thyroglobulin Rattus norvegicus 185-198 986187-2 1976 Structure of the susceptible glycopeptides were found to be very similar to non-membrane glycopeptides of the complex heteropolysaccharide unit, such as the sialylated glycopeptides of thyroglobulin. Glycopeptides 89-102 thyroglobulin Rattus norvegicus 185-198 821753-7 1976 Although alpha-lactalbumin can switch the specificity of A protein from N-acetyl-D-glucosamine to D-glucose resulting in the production of lactose, no transfer of galactose was observed to beta(1 leads to 4)-linked glycose oligomers or to a collagen glycopeptide, D-glycopyranosyl-alpha(1 leads to 2)-D-galactopyranosyloxy-beta(1 leads to 5)-lysine. Glycopeptides 250-262 lactalbumin alpha Homo sapiens 9-26 59739-12 1976 Studies of the binding of [3H] fetuin glycopeptide to normal lymphocytes demonstrate 7.5 x 10(6) saturable binding sites per cell. Glycopeptides 38-50 alpha-2-HS-glycoprotein Ovis aries 31-37 1170888-4 1975 Further study on the non-calcium-binding peptides from the tryptic digest of fragment 1 revealed the presence of two low molecular weight glycopeptides, GP-1 and GP-2. Glycopeptides 138-151 glycoprotein 2 Bos taurus 153-166 1247569-8 1976 The glycoproteins E1 and E3 revealed glycopeptides of A-type. Glycopeptides 37-50 small nucleolar RNA, H/ACA box 73A Homo sapiens 18-26 389-0 1975 Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity. Glycopeptides 36-49 O-GlcNAcase Homo sapiens 74-102 819146-1 1975 Endo beta-N-acetylglucosaminidase activity was found in a alpha-L-fucosidase preparation purified from human liver homogenates, using glycopeptides from human parotid glycoprotein as a substrate. Glycopeptides 134-147 O-GlcNAcase Homo sapiens 5-33 1170888-17 1975 The glycopeptides, GP-1 and GP-2, were distinguished from each other by differences in their behavior on ion exchange chromatography and in their amino acid composition, and from CBF by their inability to bind calcium under any conditions. Glycopeptides 4-17 glycoprotein 2 Bos taurus 19-32 1156360-9 1975 Cattle transferrin is exceptional in having two glycopeptides in which this position is occupied by serine. Glycopeptides 48-61 serotransferrin Bos taurus 7-18 5690539-8 1968 The amino acid sequences of the glycopeptides carrying these different oligosaccharides are the same in ovotransferrin and serum transferrin, showing that the carbohydrate groups are attached to the same site on the protein molecule. Glycopeptides 32-45 transferrin Homo sapiens 107-118 5101853-0 1971 Glycopeptides isolated from bovine submaxillary mucin. Glycopeptides 0-13 mucin 1, cell surface associated Bos taurus 48-53 5357018-7 1969 In ovalbumin glycopeptides with approximate mannose/hexosamine ratios 5:3 and 5:4, one and two N-acetylglucosamine residues respectively were accessible to the action of beta-N-acetylglucosaminidase. Glycopeptides 13-26 O-GlcNAcase Homo sapiens 170-198 5357018-9 1969 A mixture of alpha-mannosidase and beta-N-acetylglucosaminidase, acting on an ovalbumin glycopeptide with mannose/hexosamine ratio 5:3.7, removed nearly 4moles of mannose and 1.5moles of N-acetylglucosamine. Glycopeptides 88-100 O-GlcNAcase Homo sapiens 35-63 33848722-1 2021 A focused library of water soluble 1,2,3-triazole tethered glycopeptide conjugates derived from variety of azido-monosaccharides and aliphatic azido-alcohols were synthesized through manipulation at the C-terminus of Pam3CAG and screened for their potential as TLR2 agonistic adjuvants against HBsAg antigen. Glycopeptides 59-71 toll like receptor 2 Homo sapiens 261-265 5637058-2 1968 Preparation and properties of glycopeptides isolated from an enzymatic hydrolyzate of alpha-2-M]. Glycopeptides 30-43 alpha-2-macroglobulin Homo sapiens 86-95 33979146-4 2021 Our studies demonstrated the possibility of using synthetic glycopeptides as the adiponectin downsized mimetic for the development of novel therapeutics to treat diseases associated with deficient adiponectin. Glycopeptides 60-73 adiponectin, C1Q and collagen domain containing Mus musculus 81-92 33979146-4 2021 Our studies demonstrated the possibility of using synthetic glycopeptides as the adiponectin downsized mimetic for the development of novel therapeutics to treat diseases associated with deficient adiponectin. Glycopeptides 60-73 adiponectin, C1Q and collagen domain containing Mus musculus 197-208 33676668-5 2021 Thirty-two glycopeptides from human serum immunoglobulin G (IgG) tryptic digests were observed with a greatly improved signal-to-noise ratio (S/N) and also presented high performance in anti-interfering enrichment of glycopeptides from complex samples containing 100-fold bovine serum albumin tryptic digests. Glycopeptides 11-24 albumin Homo sapiens 279-292 33676668-5 2021 Thirty-two glycopeptides from human serum immunoglobulin G (IgG) tryptic digests were observed with a greatly improved signal-to-noise ratio (S/N) and also presented high performance in anti-interfering enrichment of glycopeptides from complex samples containing 100-fold bovine serum albumin tryptic digests. Glycopeptides 217-230 albumin Homo sapiens 279-292 33929864-6 2021 When combining results of these 2 glycopeptides with AFP, the ROC curve analysis demonstrated the AUC value increased to 0.834 (95% CI, 0.748-0.921) and 0.847 (95% CI, 0.766-0.932), respectively, as compared to that of AFP alone (AUC = 0.791, 95% CI, 0.690-0.892). Glycopeptides 34-47 alpha fetoprotein Homo sapiens 219-222 33645601-2 2021 One potential drawback in using the native MUC1 glycopeptide for vaccine design is the instability of the O-glycosyl linkage between the glycan and the peptide backbone to glycosidase. Glycopeptides 48-60 mucin 1, cell surface associated Homo sapiens 43-47 33899899-5 2021 Furthermore, an unnatural sugar, i.e., 6-azidoglucose can be transferred by XT-I introducing a reactive handle onto the glycopeptide for selective functionalization. Glycopeptides 120-132 xylosyltransferase 1 Homo sapiens 76-80 33899899-6 2021 XT-I can be coupled with beta-4-galactosyl transferase-7 for one pot synthesis of glycopeptides bearing galactose-xylose disaccharide, paving the way toward efficient chemoenzymatic synthesis of PG glycopeptides and glycoproteins. Glycopeptides 82-95 xylosyltransferase 1 Homo sapiens 0-4 33787236-11 2021 The method was employed to characterize sialylated glycopeptides derived from bovine fetuin, human alpha-1 acid glycoprotein (AGP), and human erythropoietin (EPO). Glycopeptides 51-64 erythropoietin Homo sapiens 142-156 33787236-11 2021 The method was employed to characterize sialylated glycopeptides derived from bovine fetuin, human alpha-1 acid glycoprotein (AGP), and human erythropoietin (EPO). Glycopeptides 51-64 erythropoietin Homo sapiens 158-161 33889548-8 2021 Among them, glycopeptides from APOH, HPT/HPTR, and PON1 were significantly changed in AFP-negative HCC as compared to LC. Glycopeptides 12-25 apolipoprotein H Homo sapiens 31-35 33889548-8 2021 Among them, glycopeptides from APOH, HPT/HPTR, and PON1 were significantly changed in AFP-negative HCC as compared to LC. Glycopeptides 12-25 alpha fetoprotein Homo sapiens 86-89 33889548-10 2021 The two glycopeptides HAN253WTLTPLK (H5N4S2) and (H5N4S1) corresponding to PON1 were significantly increased in AFP-negative HCC patients, as compared with LC patients. Glycopeptides 8-21 paraoxonase 1 Homo sapiens 75-79 33889548-10 2021 The two glycopeptides HAN253WTLTPLK (H5N4S2) and (H5N4S1) corresponding to PON1 were significantly increased in AFP-negative HCC patients, as compared with LC patients. Glycopeptides 8-21 alpha fetoprotein Homo sapiens 112-115 33316563-9 2021 Finally, the MOF packed in pipette tip was applied to selectively capture the N-linked endogenous glycopeptides from a healthy saliva sample and 64 unique endogenous glycopeptides were identified. Glycopeptides 98-111 lysine acetyltransferase 8 Homo sapiens 13-16 33576634-3 2021 The xylosylated glycopeptides were synthesized via solid phase synthesis, which was followed by the addition of the galactose unit by the galactosyl transferase beta4GalT7. Glycopeptides 16-29 beta-1,4-galactosyltransferase 7 Homo sapiens 161-171 33167210-0 2021 High-throughput glycopeptide profiling of prostate-specific antigen from seminal plasma by MALDI-MS. An altered total seminal plasma glycosylation has been associated with male infertility, and the highly abundant seminal plasma glycoprotein prostate-specific antigen (PSA) plays an important role in fertilization. Glycopeptides 16-28 kallikrein related peptidase 3 Homo sapiens 42-67 33167210-3 2021 In this study, we developed a novel, high-throughput PSA glycopeptide workflow, based on matrix-assisted laser desorption/ionization-mass spectrometry, allowing the discrimination of sialic acid linkage isomers via the derivatization of glycopeptides. Glycopeptides 237-250 kallikrein related peptidase 3 Homo sapiens 53-56 33167210-8 2021 Next to seminal plasma, the method is also expected to be of use for studying PSA glycopeptides derived from other biofluids and/or in other disease contexts. Glycopeptides 82-95 kallikrein related peptidase 3 Homo sapiens 78-81 33469292-5 2021 Methods: An antitumor vaccine was developed, in which MUC1 glycopeptide was used as tumor-associated antigen, alpha-GalCer served as an immune adjuvant and AuNPs was a multivalent carrier. Glycopeptides 59-71 mucin 1, cell surface associated Homo sapiens 54-58 33560106-0 2021 Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin. Glycopeptides 84-97 mucin 1, cell surface associated Homo sapiens 79-83 33560106-4 2021 Isothermal titration calorimetry (ITC) analysis of the binding of hMGL to this library of MUC1 glycopeptides revealed an enthalpy-driven process and an affinity enhancement of an order of magnitude with an increasing glycan count from 6-8 muM for monoglycosylated peptides to 0.6 muM for triglycosylated peptide. Glycopeptides 95-108 C-type lectin domain containing 10A Homo sapiens 66-70 33560106-4 2021 Isothermal titration calorimetry (ITC) analysis of the binding of hMGL to this library of MUC1 glycopeptides revealed an enthalpy-driven process and an affinity enhancement of an order of magnitude with an increasing glycan count from 6-8 muM for monoglycosylated peptides to 0.6 muM for triglycosylated peptide. Glycopeptides 95-108 mucin 1, cell surface associated Homo sapiens 90-94 33406838-7 2021 Our recently developed liquid chromatography-mass spectrometry methodology allowed us to identify LacdiNAc structural motifs on all occupied N-glycopeptides and polyLacNAc structures on six glycopeptides of the spike protein. Glycopeptides 143-156 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 211-216 33316563-9 2021 Finally, the MOF packed in pipette tip was applied to selectively capture the N-linked endogenous glycopeptides from a healthy saliva sample and 64 unique endogenous glycopeptides were identified. Glycopeptides 166-179 lysine acetyltransferase 8 Homo sapiens 13-16 33613735-3 2021 Glycopeptide-modified nanodisks (Gly-A7R-NDs), which demonstrated high capacity of brain targeting via GLUT-mediated transcytosis in our previous reports, were utilized to better understand the whole transcytosis process. Glycopeptides 0-12 solute carrier family 2 member 1 Homo sapiens 103-107 32885544-4 2021 Although the initial yields of the EPO 1-28 glycopeptides were satisfactory, they could be markedly improved by increasing the purity of the peptide using a reversed-phase high-performance liquid chromatography (RP-HPLC) purification of the protected peptide. Glycopeptides 44-57 erythropoietin Homo sapiens 35-38 33001366-0 2020 TF-containing MUC1 glycopeptides fail to entice Galectin-1 recognition of tumor-associated Thomsen-Freidenreich (TF) antigen (CD176) in solution. Glycopeptides 19-32 coagulation factor III, tissue factor Homo sapiens 0-2 32239131-8 2020 Significant predictors for ARO colonization on NF admission included lower functional status (adjusted odds ratio [aOR]>1 for all four AROs) and recent exposure to glycopeptides (aOR>2 for VREfm, VREfc and MRSA) or 3rd/4th-generation cephalosporins (aOR>2 for MRSA and VREfm). Glycopeptides 164-177 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 27-30 32363391-7 2020 Our data on the N- and O-glycosylation are strengthened by extensive manual interpretation of each glycopeptide spectra in addition to using bioinformatics tools to confirm the complexity of glycosylation in the spike protein. Glycopeptides 99-111 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 212-217 33010570-1 2020 The synthesis of MUC1 glycopeptides bearing modified tumor-associated carbohydrate antigens (TACAs) represents an effective strategy to develop potential antitumor vaccines that trigger strong immune response. Glycopeptides 22-35 mucin 1, cell surface associated Homo sapiens 17-21 33001366-0 2020 TF-containing MUC1 glycopeptides fail to entice Galectin-1 recognition of tumor-associated Thomsen-Freidenreich (TF) antigen (CD176) in solution. Glycopeptides 19-32 mucin 1, cell surface associated Homo sapiens 14-18 32615213-0 2020 The reorganization of conformations, stability and aggregation of serum albumin isomers through the interaction of glycopeptide antibiotic teicoplanin: A thermodynamic and spectroscopy study. Glycopeptides 115-127 albumin Homo sapiens 66-79 32615213-2 2020 In this work, we study the binding of teicoplanin (TPN), a glycopeptide antibiotic, with bovine serum albumin (BSA) in its neutral (N), physiological (P) and basic (B) forms, which exist at pH 6, pH 7.4 and pH 9, respectively. Glycopeptides 59-71 albumin Homo sapiens 96-109 33182731-5 2020 Further, utilizing enhanced intact glycopeptide identification afforded by the NGAG workflow, we found that the sugar analog 1,3,4-O-Bu3ManNAc, a "high flux" metabolic precursor for sialic acid biosynthesis, increased sialylation of secreted proteins including recombinant human erythropoietin (rhEPO). Glycopeptides 35-47 erythropoietin Homo sapiens 279-293 33073321-4 2020 Benefitting from the merits of Zr-MOF and glucose-6-phosphate, the as-designed composite exhibits good selectivity (the mass ratio of HRP digests to BSA digests was up to1:200) and low limit of detection (0.1 fmol muL-1) towards the recognition of glycopeptides from standard samples. Glycopeptides 248-261 mitochondrial E3 ubiquitin protein ligase 1 Homo sapiens 214-219 32786366-5 2020 Moreover, we found that the helicity of glycopeptides can affect its antitumor activity and proteolytic stability, and the alpha-linked D-monosaccharides can effectively improve the anti-tumor activity of HYL. Glycopeptides 40-53 megakaryocyte-associated tyrosine kinase Homo sapiens 205-208 33073321-6 2020 Further gene ontology analysis of molecular function and biological process revealed that 13 original glycoproteins of the identified glycopeptides from urine of patients significantly participate in diverse cancer-associated events, including collagen binding, immunoglobulin receptor binding, antigen binding, and complement activation process. Glycopeptides 134-147 megakaryocyte and platelet inhibitory receptor G6b Homo sapiens 262-285 32752208-1 2020 Background: Sialidosis is a rare autosomal recessive disease caused by NEU1 mutations, leading to neuraminidase deficiency and accumulation of sialic acid-containing oligosaccharides and glycopeptides into the tissues. Glycopeptides 187-200 neuraminidase 1 Homo sapiens 71-75 32610041-5 2020 We demonstrate the efficient utilization of such microscale glycopeptide libraries to determine the specificity of glycan-recognizing antibodies (e.g., CTD110.6) using microarrays, enzyme specificity on-array and in-solution (e.g., ST6GalNAc1, GCNT1, and T-synthase), and binding kinetics using fluorescence polarization. Glycopeptides 60-72 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Homo sapiens 232-242 32610041-5 2020 We demonstrate the efficient utilization of such microscale glycopeptide libraries to determine the specificity of glycan-recognizing antibodies (e.g., CTD110.6) using microarrays, enzyme specificity on-array and in-solution (e.g., ST6GalNAc1, GCNT1, and T-synthase), and binding kinetics using fluorescence polarization. Glycopeptides 60-72 glucosaminyl (N-acetyl) transferase 1 Homo sapiens 244-249 32610041-5 2020 We demonstrate the efficient utilization of such microscale glycopeptide libraries to determine the specificity of glycan-recognizing antibodies (e.g., CTD110.6) using microarrays, enzyme specificity on-array and in-solution (e.g., ST6GalNAc1, GCNT1, and T-synthase), and binding kinetics using fluorescence polarization. Glycopeptides 60-72 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Homo sapiens 255-265 32669364-0 2020 Differential splicing of the lectin domain of an O-glycosyltransferase modulates both peptide and glycopeptide preferences. Glycopeptides 98-110 super sex combs Drosophila melanogaster 49-70 32786443-10 2020 To the best of our knowledge, this is the first report of the AQUA of N-glycosylated AFP in human sera using a stable isotope-labeled glycopeptide as an internal standard. Glycopeptides 134-146 alpha fetoprotein Homo sapiens 85-88 33026882-5 2020 Through systematic analysis, we found that herbal extracts combined with antibiotics, such as beta-lactams, quinolones, aminoglycosides, tetracyclines and glycopeptides, could greatly enhance the antibacterial effects of the antibiotics, reduce the dosage and toxic side effects, and reverse MRSA resistance. Glycopeptides 155-168 solute carrier family 9 member A6 Homo sapiens 292-296 32672464-3 2020 In the present study, we focused on the MUC1 associated Tn antigen (alpha-O-GalNAc-Ser/Thr), and substituted the GalNAc monosaccharide by a glycomimic to identify MUC1 based glycopeptides with increased antigenicity. Glycopeptides 174-187 mucin 1, cell surface associated Homo sapiens 163-167 32672464-6 2020 The suitability of the sp2-iminosugar glycopeptides to detect anti-MUC1 antibodies was demonstrated and serological experiments showed stage I breast cancer autoantibodies binding with a specific unnatural glycopeptide with almost no healthy serum interaction. Glycopeptides 38-51 mucin 1, cell surface associated Homo sapiens 67-71 32672464-6 2020 The suitability of the sp2-iminosugar glycopeptides to detect anti-MUC1 antibodies was demonstrated and serological experiments showed stage I breast cancer autoantibodies binding with a specific unnatural glycopeptide with almost no healthy serum interaction. Glycopeptides 38-50 mucin 1, cell surface associated Homo sapiens 67-71 32617538-6 2020 Hydrophilic glycopeptides could be selectively enriched with an extremely low limit of detection (0.33 fmol per muL) and a high selectivity (1 : 100). Glycopeptides 12-25 tripartite motif containing 37 Homo sapiens 112-115 32617538-7 2020 From 2 muL of human serum, 328 unique glycopeptides from 101 glycoproteins were identified. Glycopeptides 38-51 tripartite motif containing 37 Homo sapiens 7-10 32883391-0 2020 Production of sialic acid rich glycopeptide from bovine kappa-casein glycomacropeptide by hydrolyzing with papain. Glycopeptides 31-43 casein kappa Bos taurus 56-68 32485649-2 2020 In this short communication, we studied the effect of an organic modifier in the sample solvent on the solubility of different tryptic glycopeptides of hemopexin and haptoglobin proteins. Glycopeptides 135-148 hemopexin Homo sapiens 152-161 32775865-0 2020 Human Serum Albumin-Inspired Glycopeptide-Based Multifunctional Inhibitor of Amyloid-beta Toxicity. Glycopeptides 29-41 albumin Homo sapiens 12-19 32728216-6 2020 These initial lysosome-targeting chimaeras, which we term LYTACs, consist of a small molecule or antibody fused to chemically synthesized glycopeptide ligands that are agonists of the cation-independent mannose-6-phosphate receptor (CI-M6PR). Glycopeptides 138-150 insulin like growth factor 2 receptor Homo sapiens 184-231 32340989-0 2020 Impact of vanA-positive Enterococcus faecium exhibiting diverse susceptibility phenotypes to glycopeptides on 30-day mortality of patients with a bloodstream infection. Glycopeptides 93-106 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 10-14 32388223-2 2020 This compound is a semisynthetic glycopeptide antibiotic thought to be a mixture of five major compounds (named A2-1 through A2-5) and four minor ones (RS-1 to RS-4), all sharing the same glycopeptide core structure (dubbed A3-1) and differing only on the length of a hydrocarbon side chain. Glycopeptides 33-45 retinoschisin 1 Homo sapiens 152-164 32340989-1 2020 Introduction: This study was performed to evaluate the impacts of vanA-positivity of Enterococcus faecium (EFM) exhibiting diverse susceptibility phenotypes to glycopeptides on clinical outcomes in patients with a bloodstream infection (BSI) through a prospective, multicenter, observational study.Methods: A total of 509 patients with an EFM BSI from eight sentinel hospitals in South Korea during a two-year period were enrolled in this study. Glycopeptides 160-173 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 66-70 32220931-4 2020 Here, we describe several structures of mouse and human FUT8 in the apo state and in complex with guanosine diphosphate (GDP), a mimic of the donor substrate, and with a glycopeptide acceptor substrate at 1.80-2.50 A resolutions. Glycopeptides 170-182 fucosyltransferase 8 Homo sapiens 56-60 32439962-4 2020 The glycopeptide specific CD4+ T cells display a prominent feature of Th2 and Th17 differentiation and exert high efficacy and potency to help Env trimer humoral immune responses. Glycopeptides 4-16 CD4 molecule Homo sapiens 26-29 32439962-4 2020 The glycopeptide specific CD4+ T cells display a prominent feature of Th2 and Th17 differentiation and exert high efficacy and potency to help Env trimer humoral immune responses. Glycopeptides 4-16 endogenous retrovirus group K member 20 Homo sapiens 143-146 32439962-5 2020 Glycopeptide-induced CD4+ T cell response prior to Env trimer immunization elicits neutralizing antibody development and production of antibodies facilitating uptake of immunogens by antigen-presenting cells. Glycopeptides 0-12 CD4 molecule Homo sapiens 21-24 32439962-6 2020 Our identification of gp120 glycopeptide-induced, T cell-specific immune responses offers a foundation for developing future knowledge-based vaccines that elicit strong and long-lasting protective immune responses against HIV-1 infection. Glycopeptides 28-40 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 22-27 32203567-8 2020 In order to discover which fucosylated glycan epitopes are involved in the observed effect, we performed in-depth characterization of multiply-fucosylated N-glycans via tandem mass spectrometry analysis of the EGFR tryptic glycopeptides. Glycopeptides 223-236 epidermal growth factor receptor Homo sapiens 210-214 32212632-6 2020 Then, combined with the quantitative analysis strategy of site-specific N-glycan heterogeneity based on the diagnostic MS2 ion (peptides+GlcNAc, Y1 ions) of glycopeptides, an integrated approach for the quantitation of site-specific N-glycan heterogeneities among charge isomers was established. Glycopeptides 157-170 MS2 Homo sapiens 119-122 32370047-0 2020 Preparation and Evaluation of New Glycopeptides Obtained by Proteolysis from Corn Gluten Meal Followed by Transglutaminase-Induced Glycosylation with Glucosamine. Glycopeptides 34-47 transglutaminase 1 Homo sapiens 106-122 32370047-1 2020 New glycopeptides were generated by proteolysis from corn gluten meal (CGM) followed by transglutaminase (TGase)-induced glycosylation with glucosamine (GlcN). Glycopeptides 4-17 transglutaminase 1 Homo sapiens 88-104 32370047-1 2020 New glycopeptides were generated by proteolysis from corn gluten meal (CGM) followed by transglutaminase (TGase)-induced glycosylation with glucosamine (GlcN). Glycopeptides 4-17 transglutaminase 1 Homo sapiens 106-111 32326261-8 2020 We describe the various types of glycopeptide hypersensitivity reactions associated with glycopeptides and lipoglycopeptides, including IgE-mediated reactions, RMS, and linear immunoglobulin A bullous dermatosis, as well as describe cross-reactivity with other glycopeptides. Glycopeptides 33-45 immunoglobulin heavy constant epsilon Homo sapiens 136-139 32109354-2 2020 In our previous efforts, vaccinating rabbits with evolved HMP mimic glycopeptides containing Man9 resulted in an overall antibody response targeting the glycan core and linker rather than the full glycan or Manalpha1 2Man tips of Man9 glycans. Glycopeptides 68-81 mannosidase alpha class 1A member 1 Homo sapiens 93-97 32109354-2 2020 In our previous efforts, vaccinating rabbits with evolved HMP mimic glycopeptides containing Man9 resulted in an overall antibody response targeting the glycan core and linker rather than the full glycan or Manalpha1 2Man tips of Man9 glycans. Glycopeptides 68-81 mannosidase alpha class 2C member 1 Homo sapiens 207-216 32109354-2 2020 In our previous efforts, vaccinating rabbits with evolved HMP mimic glycopeptides containing Man9 resulted in an overall antibody response targeting the glycan core and linker rather than the full glycan or Manalpha1 2Man tips of Man9 glycans. Glycopeptides 68-81 mannosidase alpha class 1A member 1 Homo sapiens 230-234 32091889-9 2020 These glycopeptides were attributable to eleven different peptide backbones, derived from IgG1, IgG2/3, IgG4, IgA1, IgA2 and the joining chain from dimeric IgA. Glycopeptides 6-19 immunoglobulin heavy constant gamma 3 (G3m marker) Homo sapiens 96-102 32091889-9 2020 These glycopeptides were attributable to eleven different peptide backbones, derived from IgG1, IgG2/3, IgG4, IgA1, IgA2 and the joining chain from dimeric IgA. Glycopeptides 6-19 immunoglobulin heavy constant alpha 1 Homo sapiens 110-114 31729101-8 2020 Molecular dynamics simulations of the MUC1 glycopeptide and peptide revealed distinguishing differences in their conformational preferences. Glycopeptides 43-55 mucin 1, cell surface associated Homo sapiens 38-42 31545160-1 2020 Aims: Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) could be misinterpreted as "susceptible" with routine susceptibility testing procedures, and the subpopulations with reduced susceptibility to glycopeptides can lead to therapeutic failure. Glycopeptides 217-230 mitochondrial antiviral signaling protein Homo sapiens 67-72 31932717-2 2020 We explored the molecular mechanism for GalNAc-T3 glycosylation of FGF23 using engineered cell models and biophysical studies including kinetics, molecular dynamics and X-ray crystallography of GalNAc-T3 complexed to glycopeptide substrates. Glycopeptides 217-229 polypeptide N-acetylgalactosaminyltransferase 3 Homo sapiens 40-49 31932717-2 2020 We explored the molecular mechanism for GalNAc-T3 glycosylation of FGF23 using engineered cell models and biophysical studies including kinetics, molecular dynamics and X-ray crystallography of GalNAc-T3 complexed to glycopeptide substrates. Glycopeptides 217-229 fibroblast growth factor 23 Homo sapiens 67-72 31932717-2 2020 We explored the molecular mechanism for GalNAc-T3 glycosylation of FGF23 using engineered cell models and biophysical studies including kinetics, molecular dynamics and X-ray crystallography of GalNAc-T3 complexed to glycopeptide substrates. Glycopeptides 217-229 polypeptide N-acetylgalactosaminyltransferase 3 Homo sapiens 194-203 31841011-7 2020 Thus, the insertion of alpha-GalCer significantly improved the immunogenicity of the MUC1 glycopeptide and induced strong antigen-specific antitumor responses, indicating that alpha-GalCer is an effective built-in adjuvant for constructing potent chemical synthetic antitumor vaccines. Glycopeptides 90-102 mucin 1, transmembrane Mus musculus 85-89 31103168-8 2019 Compared with the identification scheme using only MS2 spectra of intact glycopeptides or glycosites, this approach enabled quantitative analysis on two levels, i.e. glycosites and site-specific glycoforms, simultaneously. Glycopeptides 73-86 minisatellites detected by probe MMS2 Mus musculus 51-54 31498587-5 2019 The conjugates of MUC1-Tf and -STn glycopeptides with Qbeta were utilized to immunize immune-tolerant human MUC1 transgenic (MUC1.Tg) mice, which elicited superior levels of anti-MUC1 IgG antibodies with titers reaching over 2 million units. Glycopeptides 35-48 mucin 1, cell surface associated Homo sapiens 108-112 31498587-5 2019 The conjugates of MUC1-Tf and -STn glycopeptides with Qbeta were utilized to immunize immune-tolerant human MUC1 transgenic (MUC1.Tg) mice, which elicited superior levels of anti-MUC1 IgG antibodies with titers reaching over 2 million units. Glycopeptides 35-48 mucin 1, cell surface associated Homo sapiens 108-112 31498587-5 2019 The conjugates of MUC1-Tf and -STn glycopeptides with Qbeta were utilized to immunize immune-tolerant human MUC1 transgenic (MUC1.Tg) mice, which elicited superior levels of anti-MUC1 IgG antibodies with titers reaching over 2 million units. Glycopeptides 35-48 mucin 1, transmembrane Mus musculus 108-112 31498587-6 2019 The IgG antibodies recognized a wide range of MUC1 glycopeptides bearing diverse glycans. Glycopeptides 51-64 mucin 1, transmembrane Mus musculus 46-50 31569686-5 2019 Here, serum levels of serotransferrin glycoforms at the glycopeptide level were measured in the sera of CCA (n = 100), PDF (n = 50), and healthy control (n = 100) subjects. Glycopeptides 56-68 transferrin Homo sapiens 22-37 31076819-9 2019 Finally, we confirmed that the area under the receiver operating characteristic curve (AUC = 0.944) for the combination of AFP and VTN increased more so than for a single glycopeptide (AUC = 0.889 for AFP and 0.792 for VTN) with respect to discriminating between HCC and cirrhosis serum. Glycopeptides 171-183 vitronectin Homo sapiens 131-134 31215694-0 2019 Glycopeptides by Linch-Pin C-H Activations for Peptide-Carbohydrate Conjugation by Manganese(I)-Catalysis. Glycopeptides 0-13 dynein light chain LC8-type 1 Homo sapiens 23-26 31642255-5 2019 The retention of glycopeptides on Poly-Trp was investigated revealing that the retention ability decreased as the acetonitrile content of the mobile phase decreased and its acidity increased. Glycopeptides 17-30 transient receptor potential cation channel subfamily C member 5 Bos taurus 39-42 31642255-6 2019 Poly-Trp exhibited higher enrichment selectivity for glycopeptides from bovine fetuin than the commercial material ZIC-HILIC, and aminated silica which could defect the interference of 100-fold amount of substance ratios of bovine serum albumin. Glycopeptides 53-66 transient receptor potential cation channel subfamily C member 5 Bos taurus 5-8 31203640-1 2019 Progranulin is a recently recognized multifunctional glycopeptide shown to be related to obesity and diabetes mellitus. Glycopeptides 53-65 granulin precursor Homo sapiens 0-11 31588183-3 2019 Utilizing an anti-tumor vaccine based on a synthetically prepared glycopeptide, we generated a monoclonal antibody (mAb) GGSK-1/30, selectively recognizing human tumor-associated MUC1. Glycopeptides 66-78 mucin 1, cell surface associated Homo sapiens 179-183 31247730-0 2019 Glycopeptide Nanofiber Platform for Abeta-Sialic Acid Interaction Analysis and Highly Sensitive Detection of Abeta. Glycopeptides 0-12 amyloid beta precursor protein Homo sapiens 36-41 31247730-0 2019 Glycopeptide Nanofiber Platform for Abeta-Sialic Acid Interaction Analysis and Highly Sensitive Detection of Abeta. Glycopeptides 0-12 amyloid beta precursor protein Homo sapiens 109-114 31079966-0 2019 Synthetic glycopeptides reveal specific binding pattern and conformational change at O-mannosylated position of alpha-dystroglycan by POMGnT1 catalyzed GlcNAc modification. Glycopeptides 10-23 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Homo sapiens 134-141 30952968-1 2019 We have previously studied the generation of immune responses after vaccination with tumor-associated carbohydrate antigen (TACA)-containing glycopeptides from the tandem repeat (TR) sequence of MUC4, an aberrantly expressed mucin in pancreatic adenocarcinomas. Glycopeptides 141-154 mucin-4 Oryctolagus cuniculus 195-199 30795648-5 2019 We demonstrate that SP2 can be applied to phosphopeptides and glycopeptides and that the approach is compatible with robotic liquid handling for automated sample processing. Glycopeptides 62-75 Sp2 transcription factor Homo sapiens 20-23 30952968-4 2019 Glycan microarray analysis showed an intriguing binding pattern where the antiserum showed near complete specificity for MUC4 TR glycopeptides and peptides, relative to all components on the array. Glycopeptides 129-142 mucin-4 Oryctolagus cuniculus 121-125 30032777-5 2018 The enrichment efficiency of MAR@MOP to glycopeptides was demonstrated by trapping N-linked glycopeptides from tryptic digests of human immunoglobulin G (IgG), horseradish peroxidase (HRP) and bovine fetuin. Glycopeptides 40-53 interferon regulatory factor 1 Homo sapiens 29-36 30827091-5 2019 This hydrophilic probe presents an extremely high performance in anti-interfering enrichment of glycopeptides from mimic complex samples, even when the molar ratio of immunoglobulin G versus bovine serum albumin was up to about 1:5000. Glycopeptides 96-109 albumin Homo sapiens 198-211 30504228-5 2019 As the MGLshort H259T variant could still bind a single GalNAc monosaccharide on this array, we next investigated its binding characteristics to Tn-containing glycopeptides derived from the MGL ligands mucin 1 (MUC1), MUC2, and CD45. Glycopeptides 159-172 C-type lectin domain containing 10A Homo sapiens 7-10 30504228-5 2019 As the MGLshort H259T variant could still bind a single GalNAc monosaccharide on this array, we next investigated its binding characteristics to Tn-containing glycopeptides derived from the MGL ligands mucin 1 (MUC1), MUC2, and CD45. Glycopeptides 159-172 mucin 1, cell surface associated Homo sapiens 202-209 31364056-2 2019 As the MHC processing pathways communicate cellular health to circulating CD8+ and CD4+ T-cells, MHC-associated glycopeptides are likely a source of neoantigens in cancer. Glycopeptides 112-125 CD8a molecule Homo sapiens 74-77 31364056-2 2019 As the MHC processing pathways communicate cellular health to circulating CD8+ and CD4+ T-cells, MHC-associated glycopeptides are likely a source of neoantigens in cancer. Glycopeptides 112-125 CD4 molecule Homo sapiens 83-86 30384610-3 2018 Here we report the chemoenzymatic synthesis, antigenicity, and immunogenicity of the V3 N334 glycopeptides from HIV-1 A244 gp120, a key component in the partially successful Thai clinical trials. Glycopeptides 93-106 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 123-128 30794378-8 2019 In addition, GO-PEI-Carr exhibited a unique repeatability and stability even after enrichment of glycopeptides for 20 times. Glycopeptides 97-110 arrestin 3, retinal Mus musculus 20-24 30693278-4 2018 In this study, a set of glycopeptides with modifications on the GlcNAc residue, were prepared in a recombinant full-length human OGT-catalyzed reaction, using chemoenzymatically synthesized UDP-GlcNAc derivatives. Glycopeptides 24-37 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 129-132 30344001-1 2018 We have employed genetically-encoded fragment-based discovery to identify novel glycopeptides with affinity for the dendritic cell receptor DC-SIGN. Glycopeptides 80-93 CD209 molecule Homo sapiens 140-147 30261726-7 2018 Moreover, without immunoprecipitation, this multilectin nanoprobe allows the sensitive identification of 51 glycopeptides from 10 of 12 reported sites from onco-protein EGFR. Glycopeptides 108-121 epidermal growth factor receptor Homo sapiens 169-173 30344001-2 2018 Starting from libraries of 108 mannose-conjugated peptides, we identified glycopeptides that exhibited up to a 650-fold increase in multivalent binding affinity for DC-SIGN, which is also preserved in cells. Glycopeptides 74-87 CD209 molecule Homo sapiens 165-172 30344001-5 2018 The natural framework of glycopeptide conjugates and the simplicity of orthogonal conjugation to make these glycopeptides anticipates a promising future for development of DC-SIGN-targeting moieties. Glycopeptides 108-121 CD209 molecule Homo sapiens 172-179 30001488-3 2018 Having a general architecture of N-terminal capping, glycosylation, and an integrin-binding sequence, the glycopeptides self-assemble to form a dynamic continuum of nanostructures (i.e., from nanoparticles to nanofibers) to affect the interactions of integrins, E-selectin, and cadherins with their natural ligands and to act adaptively according to the cellular environment. Glycopeptides 106-119 selectin E Homo sapiens 262-272 30115684-5 2018 Selective labeling of gp120 by N-azidoacetylmannosamine (ManNAz) and N-azidoacetylgalactosamine (GalNAz) incorporation into the gp120 glycan shield was characterized by MS of tryptic glycopeptides. Glycopeptides 183-196 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 22-27 30115684-5 2018 Selective labeling of gp120 by N-azidoacetylmannosamine (ManNAz) and N-azidoacetylgalactosamine (GalNAz) incorporation into the gp120 glycan shield was characterized by MS of tryptic glycopeptides. Glycopeptides 183-196 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 128-133 29885416-7 2018 Compared to non-glycosylated nanodisk, glycopeptide modification could significantly enhance the uptake of disks by brain capillary endothelial cells through glucose transporter 1 (GLUT1). Glycopeptides 39-51 solute carrier family 2 member 1 Homo sapiens 158-179 29885416-7 2018 Compared to non-glycosylated nanodisk, glycopeptide modification could significantly enhance the uptake of disks by brain capillary endothelial cells through glucose transporter 1 (GLUT1). Glycopeptides 39-51 solute carrier family 2 member 1 Homo sapiens 181-186 29784830-7 2018 We demonstrate that 14-3-3 proteins bind O-GlcNAc moieties in human cells, and we present the structures of 14-3-3beta/alpha and gamma bound to glycopeptides, providing biophysical insights into O-GlcNAc-mediated protein-protein interactions. Glycopeptides 144-157 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 195-203 29972295-8 2018 In contrast, the alpha-2-6 sialylated glycoform of the O-glycopeptide of SHBG increases in liver cirrhosis, and a significant 2-fold further increase is observed in HCC. Glycopeptides 57-69 immunoglobulin binding protein 1 Homo sapiens 17-26 29972295-8 2018 In contrast, the alpha-2-6 sialylated glycoform of the O-glycopeptide of SHBG increases in liver cirrhosis, and a significant 2-fold further increase is observed in HCC. Glycopeptides 57-69 sex hormone binding globulin Homo sapiens 73-77 29751197-0 2018 Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach. Glycopeptides 49-61 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 14-29 29185859-11 2018 In conclusion, this study investigated the nature of RIF-R in Italy among RIF-R-MRSA strains, finding a prevalence of ST228, strongly associated with reduced susceptibility to glycopeptides (hVISA). Glycopeptides 176-189 mitochondrial antiviral signaling protein Homo sapiens 191-196 29557479-7 2018 We found that boronic acid chemistry in this study preferred to capture glycopeptides with high mannose glycans, ZIC-HILIC enriched most N-glycopeptides and did not show significant preference during enrichment and PGC was not suitable for separating glycopeptides with a long amino acid sequence. Glycopeptides 139-152 zinc finger protein of the cerebellum 1 Mus musculus 113-116 29644550-2 2018 However, aiming for resolving site-specific glycosylation of sulfated glycopeptides by direct LC-MS2 sequencing is technically most challenging. Glycopeptides 70-83 MS2 Homo sapiens 97-100 30136494-0 2018 [Preparation of cobalt phthalocyanine functionalized polymer monolith and application to enrichment of transferrin glycopeptides]. Glycopeptides 115-128 transferrin Homo sapiens 103-114 29642865-4 2018 RESULTS: Leucine-rich alpha-2-glycoprotein-1 with fucosylated triantennary N-glycan (LRG-FTG) was identified as CRC marker after evaluating 30,000 candidate glycopeptide peaks. Glycopeptides 157-169 leucine rich alpha-2-glycoprotein 1 Homo sapiens 9-44 29642865-4 2018 RESULTS: Leucine-rich alpha-2-glycoprotein-1 with fucosylated triantennary N-glycan (LRG-FTG) was identified as CRC marker after evaluating 30,000 candidate glycopeptide peaks. Glycopeptides 157-169 leucine rich alpha-2-glycoprotein 1 Homo sapiens 85-88 30136494-4 2018 After enrichment of transferrin through the functionalized monolith, 17 glycopeptides were identified by electrospray ionization quadrupole time-of-flight mass spectrometry. Glycopeptides 72-85 transferrin Homo sapiens 20-31 30136494-5 2018 When the concentration of transferrin was reduced to 8.8x10-10mol/L, three glycopeptides could still be obtained. Glycopeptides 75-88 transferrin Homo sapiens 26-37 29107699-6 2017 Rabbit immunization revealed that the synthetic self-adjuvant glycopeptide could elicit substantial glycan-dependent antibodies that exhibited broader recognition of HIV-1 gp120s than the non-glycosylated V3 peptide. Glycopeptides 62-74 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 172-177 29285644-5 2018 Serum haptoglobin enriched by immunoaffinity chromatography was subjected to multispecific proteolysis to generate site-specific glycopeptides and to investigate the macroheterogeneity and microheterogeneity. Glycopeptides 129-142 haptoglobin Homo sapiens 6-17 29046357-8 2017 The crystal structures of PILRalpha complexed with these glycopeptides highlighted the importance of stereochemical positioning of the O4 atom of the sugar moiety. Glycopeptides 57-70 paired immunoglobin like type 2 receptor alpha Homo sapiens 26-35 29045792-0 2017 Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile toward Macrophage Galactose-Type Lectin (MGL) Orthologs. Glycopeptides 0-13 mucin 1, transmembrane Mus musculus 56-60 29166012-1 2017 A structure-based design of a new generation of tumor-associated glycopeptides with improved affinity against two anti-MUC1 antibodies is described. Glycopeptides 65-78 mucin 1, cell surface associated Homo sapiens 119-123 29022615-0 2017 Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides. Glycopeptides 105-118 LOC100508689 Homo sapiens 14-19 29022615-0 2017 Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides. Glycopeptides 105-118 mucin 1, cell surface associated Homo sapiens 100-104 29045792-0 2017 Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile toward Macrophage Galactose-Type Lectin (MGL) Orthologs. Glycopeptides 0-13 C-type lectin domain family 10, member A Mus musculus 98-130 29045792-0 2017 Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile toward Macrophage Galactose-Type Lectin (MGL) Orthologs. Glycopeptides 0-13 C-type lectin domain family 10, member A Mus musculus 132-135 29016103-9 2017 In particular, isobaric tag labeled glycopeptides after C18 desalting could be readily enriched by SAX and RAX cartridges but not by HILIC to enable quantitative glycoproteomics. Glycopeptides 36-49 Bardet-Biedl syndrome 9 Homo sapiens 56-59 29045792-0 2017 Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile toward Macrophage Galactose-Type Lectin (MGL) Orthologs. Glycopeptides 61-74 mucin 1, transmembrane Mus musculus 56-60 29045792-0 2017 Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile toward Macrophage Galactose-Type Lectin (MGL) Orthologs. Glycopeptides 61-74 C-type lectin domain family 10, member A Mus musculus 98-130 29045792-0 2017 Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile toward Macrophage Galactose-Type Lectin (MGL) Orthologs. Glycopeptides 61-74 C-type lectin domain family 10, member A Mus musculus 132-135 29045792-3 2017 To estimate the ability of distinct MGL orthologs to recognize aberrant glycan cores in mucins, we applied evanescent-field detection to a versatile MUC1-like glycopeptide microarray platform. Glycopeptides 159-171 mucin 1, transmembrane Mus musculus 149-153 28921955-4 2017 Three enzymes, trypsin, AspN, and pepsin, were used separately to generate suitable glycopeptides for online LC tandem MS analysis. Glycopeptides 84-97 asporin Homo sapiens 24-28 28675699-2 2017 We showed that vaccines containing tumor-associated human MUC1 glycopeptides induce strong humoral antitumor responses in mice. Glycopeptides 63-76 mucin 1, cell surface associated Homo sapiens 58-62 28678517-3 2017 Here, we examined the specificity and activity of human FUT8 toward tri- and tetra-antennary N-glycans in the forms of glycopeptides. Glycopeptides 119-132 fucosyltransferase 8 Homo sapiens 56-60 28741944-2 2017 To analyze how UGGT recognizes non-native glycoproteins, we chemically synthesized site-specifically 15N-labeled interleukin 8 (IL-8) C-terminal (34-72) glycopeptides bearing a Man9GlcNAc2 (M9) oligosaccharide. Glycopeptides 153-166 C-X-C motif chemokine ligand 8 Homo sapiens 113-126 28741944-2 2017 To analyze how UGGT recognizes non-native glycoproteins, we chemically synthesized site-specifically 15N-labeled interleukin 8 (IL-8) C-terminal (34-72) glycopeptides bearing a Man9GlcNAc2 (M9) oligosaccharide. Glycopeptides 153-166 C-X-C motif chemokine ligand 8 Homo sapiens 128-132 28681051-5 2017 ENGase biocatalysts are now finding burgeoning application for the production of biologically active glycopeptides and glycoproteins, including therapeutic monoclonal antibodies (mAbs) for which the oligosaccharides have been remodelled to optimise effector functions. Glycopeptides 101-114 endo-beta-N-acetylglucosaminidase Homo sapiens 0-6 28514044-4 2017 Using synthetic glycopeptides with O-GalNAc (the Tn antigen) or O-GlcNAc, we demonstrated that the method is selective for glycopeptides with O-GalNAc and can distinguish between these two modifications. Glycopeptides 16-29 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 35-72 29048831-4 2017 Thus, POP-1 was tried to be used for glycopeptides enrichment from tryptic digest of standard protein and complex biosamples in hydrophilic mode. Glycopeptides 37-50 processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) Mus musculus 6-11 28685598-2 2017 MATERIALS & METHODS: Porcine cardiac tissue was analyzed for the presence of CgA-derived glycopeptides using a global O-glycoproteomic strategy. Glycopeptides 93-106 chromogranin A Homo sapiens 81-84 28685598-5 2017 RESULTS: We identified CgA-derived glycopeptides exclusively in the atrial tissue. Glycopeptides 35-48 chromogranin A Homo sapiens 23-26 28623326-7 2017 This approach was applied for the analysis of tryptic glycopeptides of prostate specific antigen, which shows highly complex and heterogeneous glycosylation. Glycopeptides 54-67 kallikrein related peptidase 3 Homo sapiens 71-96 28514044-4 2017 Using synthetic glycopeptides with O-GalNAc (the Tn antigen) or O-GlcNAc, we demonstrated that the method is selective for glycopeptides with O-GalNAc and can distinguish between these two modifications. Glycopeptides 123-136 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 35-72 28442774-2 2017 In this study, for the first time, a "one for two" hydrophilic magnetic amino-functionalized metal-organic framework (MOF) was designed and synthesized for selective enrichment of both glycopeptides and phosphopeptides. Glycopeptides 185-198 lysine acetyltransferase 8 Homo sapiens 93-122 28440596-2 2017 However, tumor-associated aberrantly glycosylated MUC1 glycopeptides are endogenous structures, "self-antigens", that exhibit only low immunogenicity. Glycopeptides 55-68 mucin 1, cell surface associated Homo sapiens 50-54 28247191-8 2017 The results of PLS-DA showed that 167 glycopeptides were found to be significantly different between the naturally derived and recombinant hCG products. Glycopeptides 38-51 chorionic gonadotropin subunit beta 5 Homo sapiens 139-142 28391691-0 2017 Both PepT1 and GLUT Intestinal Transporters Are Utilized by a Novel Glycopeptide Pro-Hyp-CONH-GlcN. Glycopeptides 68-80 solute carrier family 15 member 1 Homo sapiens 5-10 28391691-0 2017 Both PepT1 and GLUT Intestinal Transporters Are Utilized by a Novel Glycopeptide Pro-Hyp-CONH-GlcN. Glycopeptides 68-80 solute carrier family 2 member 1 Homo sapiens 15-19 27909778-3 2017 Here, we present a novel, simplified technique for HILIC enrichment termed "Drop-HILIC", which was applied to systematically evaluate the mobile phase effect on ZIC-HILIC (zwitterionic type of hydrophilic interaction chromatography) glycopeptide enrichment. Glycopeptides 233-245 Zic family member 1 Homo sapiens 161-164 28251761-6 2017 Here, we report the crystal structures of the POMK catalytic domain in the absence and presence of an ATP analogue and O-mannosylated glycopeptide. Glycopeptides 134-146 protein O-mannose kinase Homo sapiens 46-50 28298421-5 2017 Fluorophore-labeled Man9-V3 glycopeptides bound to bnAb memory B cells and were able to be used to isolate a V3-glycan bnAb from an HIV-1-infected individual. Glycopeptides 28-41 mannosidase alpha class 1A member 1 Homo sapiens 20-24 27966990-5 2017 The objectives of the present study were to characterize N-glycosylation sites in VEGFR-2 via enzymatic release of the glycans and concomitant incorporation of 18O into formerly N-glycosylated sites followed by tandem mass spectrometry (MS/MS) analysis to determine N-glycosylation site occupancy and the site-specific N-glycan heterogeneity of VEGFR-2 glycopeptides. Glycopeptides 353-366 kinase insert domain receptor Homo sapiens 82-89 28139739-0 2017 Combination of cephalosporins with vancomycin or teicoplanin enhances antibacterial effect of glycopeptides against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and VISA. Glycopeptides 94-107 mitochondrial antiviral signaling protein Homo sapiens 177-182 28139739-0 2017 Combination of cephalosporins with vancomycin or teicoplanin enhances antibacterial effect of glycopeptides against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and VISA. Glycopeptides 94-107 mitochondrial antiviral signaling protein Homo sapiens 178-182 27873468-0 2017 Synthetic Mucin-Like Glycopeptides as Versatile Tools to Measure Effects of Glycan Structure/Density/Position on the Interaction with Adhesion/Growth-Regulatory Galectins in Arrays. Glycopeptides 21-34 LOC100508689 Homo sapiens 10-15 28323416-3 2017 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HCC), the assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides), respectively. Glycopeptides 146-159 alpha fetoprotein Homo sapiens 19-36 28323416-3 2017 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HCC), the assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides), respectively. Glycopeptides 146-159 alpha fetoprotein Homo sapiens 38-41 28323416-3 2017 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HCC), the assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides), respectively. Glycopeptides 146-158 alpha fetoprotein Homo sapiens 19-36 28323416-3 2017 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HCC), the assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides), respectively. Glycopeptides 146-158 alpha fetoprotein Homo sapiens 38-41 28323416-3 2017 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HCC), the assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides), respectively. Glycopeptides 257-270 alpha fetoprotein Homo sapiens 38-41 28323416-3 2017 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HCC), the assay has high purification specificity (20 glycopeptides) with 2-fold and 10-fold superior total glycopeptide intensity compared to non-one-pot method (9 glycopeptides) or without enrichment (6 glycopeptides), respectively. Glycopeptides 257-270 alpha fetoprotein Homo sapiens 38-41 27957777-0 2017 Photoinduced Thiol-ene Chemistry Applied to the Synthesis of Self-Assembling Elastin-Inspired Glycopeptides. Glycopeptides 94-107 elastin Homo sapiens 77-84 27957777-2 2017 Herein, for the first time, taking advantage of thiol-ene chemistry coupled to solid-phase peptide synthesis, a self-assembling peptide inspired by elastin protein was bioconjugated to three carbohydrates in order to obtain the corresponding glycopeptides. Glycopeptides 242-255 elastin Homo sapiens 148-155 27810711-0 2016 Obstacles and solutions for chemical synthesis of syndecan-3 (53-62) glycopeptides with two heparan sulfate chains. Glycopeptides 69-82 syndecan 3 Homo sapiens 50-60 27743362-5 2017 These glycopeptides are then separated and detected using an integrated C18-porous graphitized carbon-liquid chromatography (PGC-LC) setup online coupled to a high-resolution electrospray ionization (ESI)-quadrupole time-of-flight (QTOF)-mass spectrometer operated in a combined higher- and lower-energy CID (stepping-energy CID) mode. Glycopeptides 6-19 Bardet-Biedl syndrome 9 Homo sapiens 72-75 27810711-4 2016 For assembly of glycans, a convergent 3+2+3 approach was developed producing two different octasaccharide amino acid cassettes, which were utilized towards syndecan-3 glycopeptides. Glycopeptides 167-180 syndecan 3 Homo sapiens 156-166 27487254-2 2016 However, appropriate analytical tools to characterize acidic and high-molecular-weight (hMW) glycopeptides are still lacking. Glycopeptides 93-106 cilia and flagella associated protein 97 Homo sapiens 88-91 27591639-3 2016 The functionalized magnetic nanoparticles exhibited superior performance in glycopeptide enrichment of HRP tryptic digest, demonstrating low detection limit (0.04ng/muL), high selectivity (a mixture of HRP and BSA at the mass ratio of 1:50) and reproducibility (5 repeating cycles). Glycopeptides 76-88 tripartite motif containing 37 Homo sapiens 165-168 27591658-0 2016 Classification of congenital disorders of glycosylation based on analysis of transferrin glycopeptides by capillary liquid chromatography-mass spectrometry. Glycopeptides 89-102 transferrin Homo sapiens 77-88 27477788-1 2016 Glycopeptide antibiotic biosynthesis involves a complex cascade of reactions centred on a non-ribosomal peptide synthetase and modifiying proteins acting in trans, such as Cytochrome P450 enzymes. Glycopeptides 0-12 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 183-187 27752135-0 2016 F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE. Glycopeptides 24-36 zinc finger protein, FOG family member 1 Homo sapiens 0-5 27487254-3 2016 In this study, we demonstrate that the addition of supercharging reagent, m-nitrobenzyl alcohol (m-NBA), into mobile phases greatly facilitates the analysis of acidic and hMW glycopeptides. Glycopeptides 175-188 cilia and flagella associated protein 97 Homo sapiens 171-174 27487254-7 2016 Our results indicated that incorporation of m-NBA into reversed-phase liquid chromatography (LC) solvents improves sensitivity, charging, and chromatographic resolution for acidic and hMW glycopeptides. Glycopeptides 188-201 cilia and flagella associated protein 97 Homo sapiens 184-187 26399494-3 2015 However, the enzymatic release of glycopeptides captured by hydrazide beads through direct incubation of the beads with PNGase F is not efficient due to the inherent steric hindrance effect. Glycopeptides 34-47 N-glycanase 1 Homo sapiens 120-126 27380866-7 2016 Moreover, the elicited antisera reacted with the STn-MUC1 antigen-positive tumor cells, indicating that the carbohydrate antigen modification strategy may hold potential to overcome the weak immunogenicity of natural MUC1 glycopeptides. Glycopeptides 222-235 mucin 1, transmembrane Mus musculus 217-221 27340743-1 2016 Synthetic macromolecular MUC1 glycopeptides have been used to unravel molecular mechanisms in antibody recognition of disease-specific epitopes. Glycopeptides 30-43 mucin 1, cell surface associated Homo sapiens 25-29 27340743-3 2016 We have accomplished the synthesis of 77 amino acid MUC1 glycopeptides (MW = 12 759) having three major antigenic O-glycoforms [Tn, core 1 (T), and core 2 structures] at 10 designated positions out of 19 potential O-glycosylation sites. Glycopeptides 57-70 mucin 1, cell surface associated Homo sapiens 52-56 26858738-5 2016 Mass spectrometric analysis of IgA1 glycopeptides revealed the presence of complex biantennary N-glycans with terminal N-acetylglucosamine present on the N-glycosylation site of the CH2 domain in the IgA1 alpha chain. Glycopeptides 36-49 immunoglobulin heavy constant alpha 1 Homo sapiens 31-35 26858738-5 2016 Mass spectrometric analysis of IgA1 glycopeptides revealed the presence of complex biantennary N-glycans with terminal N-acetylglucosamine present on the N-glycosylation site of the CH2 domain in the IgA1 alpha chain. Glycopeptides 36-49 immunoglobulin heavy constant alpha 1 Homo sapiens 200-204 26824070-3 2016 A segment coupling strategy performed by native chemical ligation using six peptide segments including glycopeptides yielded homogeneous EPO glycopeptides, and folding experiments of these glycopeptides afforded the correctly folded EPO glycoforms. Glycopeptides 103-116 erythropoietin Homo sapiens 137-140 26582205-4 2016 Sequential digestion of TIB-141 with lysyl endopeptidase and trypsin resulted in the identification of a glycopeptide (H-Lys13-Try3; 48 amino acid residues) with a single N-linked oligosaccharide near the N terminus capable of neutralizing the effect of galectin-9 and another glycopeptide with two N-linked oligosaccharides (H-Lys13-Try1; 16 amino acid residues) having lower activity. Glycopeptides 105-117 PRSS3 pseudogene 3 Homo sapiens 127-131 26582205-4 2016 Sequential digestion of TIB-141 with lysyl endopeptidase and trypsin resulted in the identification of a glycopeptide (H-Lys13-Try3; 48 amino acid residues) with a single N-linked oligosaccharide near the N terminus capable of neutralizing the effect of galectin-9 and another glycopeptide with two N-linked oligosaccharides (H-Lys13-Try1; 16 amino acid residues) having lower activity. Glycopeptides 105-117 galectin 9 Homo sapiens 254-264 26582205-4 2016 Sequential digestion of TIB-141 with lysyl endopeptidase and trypsin resulted in the identification of a glycopeptide (H-Lys13-Try3; 48 amino acid residues) with a single N-linked oligosaccharide near the N terminus capable of neutralizing the effect of galectin-9 and another glycopeptide with two N-linked oligosaccharides (H-Lys13-Try1; 16 amino acid residues) having lower activity. Glycopeptides 105-117 serine protease 1 Homo sapiens 334-338 26467158-7 2016 We purified BACE1 from Neuro2A cells and performed LC/ESI/MS analysis for BACE1-derived glycopeptides and mapped bisecting GlcNAc-modified sites on BACE1. Glycopeptides 88-101 beta-site APP cleaving enzyme 1 Mus musculus 74-79 26467158-7 2016 We purified BACE1 from Neuro2A cells and performed LC/ESI/MS analysis for BACE1-derived glycopeptides and mapped bisecting GlcNAc-modified sites on BACE1. Glycopeptides 88-101 beta-site APP cleaving enzyme 1 Mus musculus 74-79 26700048-0 2016 Characterization of Protein N-Glycosylation by Analysis of ZIC-HILIC-Enriched Intact Proteolytic Glycopeptides. Glycopeptides 97-110 Zic family member 1 Homo sapiens 59-62 27472370-4 2016 A variety of adjuvants have been used with MUC1 glycopeptides to improve their immunogenicity. Glycopeptides 48-61 mucin 1, transmembrane Mus musculus 43-47 27139140-3 2016 Here we proposed pGlyco, a novel pipeline for the identification of intact glycopeptides by using complementary MS techniques: 1) HCD-MS/MS followed by product-dependent CID-MS/MS was used to provide complementary fragments to identify the glycans, and a novel target-decoy method was developed to estimate the false discovery rate of the glycan identification; 2) data-dependent acquisition of MS3 for some most intense peaks of HCD-MS/MS was used to provide fragments to identify the peptide backbones. Glycopeptides 75-88 MS3 Homo sapiens 395-398 27139140-4 2016 By integrating HCD-MS/MS, CID-MS/MS and MS3, intact glycopeptides could be confidently identified. Glycopeptides 52-65 MS3 Homo sapiens 40-43 26610890-6 2016 We now report on the glycopeptide substrate utilization of a series of glycopeptide (human-ppGalNAc-T4, T7, T10, T12 and fly PGANT7) and peptide-preferring transferases (T2, T3 and T5) by exploiting a series of random glycopeptide substrates designed to probe the functions of their catalytic and lectin domains. Glycopeptides 21-33 Polypeptide N-Acetylgalactosaminyltransferase 7 Drosophila melanogaster 125-131 26820384-0 2016 Structure of OxyA tei: completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade. Glycopeptides 53-65 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 87-102 26820384-1 2016 Cyclization of glycopeptide antibiotic precursors occurs in either three or four steps catalyzed by Cytochrome P450 enzymes. Glycopeptides 15-27 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 100-115 26692014-0 2016 Molecular basis of antibody binding to mucin glycopeptides in lung cancer. Glycopeptides 45-58 LOC100508689 Homo sapiens 39-44 26692014-9 2016 These findings indicate that clusters of both TR backbones and sugars are essential for mAb binding to mucin glycopeptides. Glycopeptides 109-122 LOC100508689 Homo sapiens 103-108 26831703-0 2016 Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis. Glycopeptides 27-39 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 95-110 26384718-5 2015 The utility of the methodology is demonstrated in the rapid synthesis of complex glycopeptide fragments of the epithelial glycoproteins MUC5AC and MUC4 and through the total synthesis of the structured, cysteine (Cys)-free protein eglin C. Glycopeptides 81-93 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 136-142 26399494-4 2015 In this study, we developed a hydroxylamine assisted PNGase F deglycosylation (HAPD) method using the hydroxylamine to release glycopeptides captured on the hydrazide beads through the cleavage of hydrazone bonds by transamination followed with the PNGase F deglycosylation of the released glycopeptides in the free solution. Glycopeptides 127-140 N-glycanase 1 Homo sapiens 53-59 26384718-5 2015 The utility of the methodology is demonstrated in the rapid synthesis of complex glycopeptide fragments of the epithelial glycoproteins MUC5AC and MUC4 and through the total synthesis of the structured, cysteine (Cys)-free protein eglin C. Glycopeptides 81-93 mucin 4, cell surface associated Homo sapiens 147-151 26399494-4 2015 In this study, we developed a hydroxylamine assisted PNGase F deglycosylation (HAPD) method using the hydroxylamine to release glycopeptides captured on the hydrazide beads through the cleavage of hydrazone bonds by transamination followed with the PNGase F deglycosylation of the released glycopeptides in the free solution. Glycopeptides 127-140 N-glycanase 1 Homo sapiens 249-255 26399494-4 2015 In this study, we developed a hydroxylamine assisted PNGase F deglycosylation (HAPD) method using the hydroxylamine to release glycopeptides captured on the hydrazide beads through the cleavage of hydrazone bonds by transamination followed with the PNGase F deglycosylation of the released glycopeptides in the free solution. Glycopeptides 290-303 N-glycanase 1 Homo sapiens 53-59 26244810-6 2015 Glycopeptides carrying fucosylated glycans were collected by Aleuria aurantia lectin (AAL) affinity chromatography from kidney homogenates of wild-type and Fut9 knockout mice. Glycopeptides 0-13 fucosyltransferase 9 Mus musculus 156-160 25776945-4 2015 Using the potent antiviral lectin griffithsin (GRFT) as a model, we identified by NMR spectroscopy, SPR, analytical ultracentrifugation, and microcalorimetry glycopeptides that fully recapitulate the specificity and kinetics of binding to Man9 GlcNAc2 Asn and a synthetic nonamannoside. Glycopeptides 158-171 sepiapterin reductase Homo sapiens 100-103 28717478-1 2015 The combination of solid phase peptide synthesis and endo-beta-N-acetylglucosaminidase (ENGase) catalysed glycosylation is a powerful convergent synthetic method allowing access to glycopeptides bearing full-length N-glycan structures. Glycopeptides 181-194 O-GlcNAcase Homo sapiens 58-86 28717478-1 2015 The combination of solid phase peptide synthesis and endo-beta-N-acetylglucosaminidase (ENGase) catalysed glycosylation is a powerful convergent synthetic method allowing access to glycopeptides bearing full-length N-glycan structures. Glycopeptides 181-194 endo-beta-N-acetylglucosaminidase Homo sapiens 88-94 25939779-3 2015 Here we present the first crystal structures of complexes of GalNAc-T2 with glycopeptides that together with enhanced sampling molecular dynamics simulations demonstrate a cooperative mechanism by which the lectin domain enables free acceptor sites binding of glycopeptides into the catalytic domain. Glycopeptides 76-89 polypeptide N-acetylgalactosaminyltransferase 2 Homo sapiens 61-70 26129647-6 2015 The most notable feature of the binding of MUC1 glycopeptides to galectin-3 was a shift from a favorable enthalpy to an entropy-driven binding process. Glycopeptides 48-61 mucin 1, cell surface associated Homo sapiens 43-47 26129647-6 2015 The most notable feature of the binding of MUC1 glycopeptides to galectin-3 was a shift from a favorable enthalpy to an entropy-driven binding process. Glycopeptides 48-61 galectin 3 Homo sapiens 65-75 25939779-3 2015 Here we present the first crystal structures of complexes of GalNAc-T2 with glycopeptides that together with enhanced sampling molecular dynamics simulations demonstrate a cooperative mechanism by which the lectin domain enables free acceptor sites binding of glycopeptides into the catalytic domain. Glycopeptides 260-273 polypeptide N-acetylgalactosaminyltransferase 2 Homo sapiens 61-70 25776945-4 2015 Using the potent antiviral lectin griffithsin (GRFT) as a model, we identified by NMR spectroscopy, SPR, analytical ultracentrifugation, and microcalorimetry glycopeptides that fully recapitulate the specificity and kinetics of binding to Man9 GlcNAc2 Asn and a synthetic nonamannoside. Glycopeptides 158-171 mannosidase alpha class 1A member 1 Homo sapiens 239-243 25548287-5 2015 The gC-1 O-glycosylation was regulated in an orderly manner initiated by synchronous addition of one GalNAc unit each to Thr-87 and Thr-91 and one GalNAc unit to either Thr-99 or Thr-101, forming a core glycopeptide for subsequent additions of in all 11 GalNAc residues to selected Ser and Thr residues of the Thr-76-Lys-107 stretch of the mucin domain. Glycopeptides 203-215 olfactomedin 4 Homo sapiens 4-8 25755023-6 2015 In this study, MUC4 tandem-repeat glycopeptides were conjugated to the tetanus toxoid and used for vaccination of mice. Glycopeptides 34-47 mucin 4 Mus musculus 15-19 25748228-2 2015 Herein, we report a suitable (18)F-labeled high-molecular-weight glycopeptide for imaging of peripheral neuropeptide Y (NPY) Y1 receptor (Y1R)-positive tumors by preclinical small-animal positron emission tomography (PET). Glycopeptides 65-77 neuropeptide Y Mus musculus 120-123 25748228-2 2015 Herein, we report a suitable (18)F-labeled high-molecular-weight glycopeptide for imaging of peripheral neuropeptide Y (NPY) Y1 receptor (Y1R)-positive tumors by preclinical small-animal positron emission tomography (PET). Glycopeptides 65-77 neuropeptide Y receptor Y1 Mus musculus 138-141 25748228-2 2015 Herein, we report a suitable (18)F-labeled high-molecular-weight glycopeptide for imaging of peripheral neuropeptide Y (NPY) Y1 receptor (Y1R)-positive tumors by preclinical small-animal positron emission tomography (PET). Glycopeptides 65-77 thyroid stimulating hormone receptor Mus musculus 217-220 25748228-9 2015 In vitro autoradiography with Y1R-positive MCF-7 tumor tissue slices indicated high specific binding of the (18)F-labeled glycopeptide, when binding was reduced by 95% ([Pra(4),F(7),P(34)]NPY) and by 86% (BIBP3226 Y1R antagonist) in competition studies. Glycopeptides 122-134 neuropeptide Y receptor Y1 Mus musculus 30-33 25748228-9 2015 In vitro autoradiography with Y1R-positive MCF-7 tumor tissue slices indicated high specific binding of the (18)F-labeled glycopeptide, when binding was reduced by 95% ([Pra(4),F(7),P(34)]NPY) and by 86% (BIBP3226 Y1R antagonist) in competition studies. Glycopeptides 122-134 neuropeptide Y Mus musculus 188-191 25748228-9 2015 In vitro autoradiography with Y1R-positive MCF-7 tumor tissue slices indicated high specific binding of the (18)F-labeled glycopeptide, when binding was reduced by 95% ([Pra(4),F(7),P(34)]NPY) and by 86% (BIBP3226 Y1R antagonist) in competition studies. Glycopeptides 122-134 neuropeptide Y receptor Y1 Mus musculus 214-217 25748228-13 2015 PET imaging studies with MCF-7 tumor-bearing nude mice demonstrated uptake of the (18)F-labeled glycopeptide in the tumor region at 60 min p.i., whereas only negligible tumor uptake was observed in animals injected with a nonbinding (18)F-labeled glycopeptide pendant as a measure of nonspecific binding. Glycopeptides 96-108 thyroid stimulating hormone receptor Mus musculus 0-3 25824568-0 2015 Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Glycopeptides 0-12 selectin P ligand Homo sapiens 26-32 25824568-0 2015 Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Glycopeptides 0-12 selectin P Homo sapiens 41-51 25723283-0 2015 Characterization of monoclonal antibody LpMab-3 recognizing sialylated glycopeptide of podoplanin. Glycopeptides 71-83 podoplanin Homo sapiens 87-97 25723283-5 2015 In this study, we produced and characterized a novel anti-podoplanin monoclonal antibody, LpMab-3, the epitope of which is a sialylated glycopeptide of podoplanin. Glycopeptides 136-148 podoplanin Homo sapiens 58-68 25723283-5 2015 In this study, we produced and characterized a novel anti-podoplanin monoclonal antibody, LpMab-3, the epitope of which is a sialylated glycopeptide of podoplanin. Glycopeptides 136-148 podoplanin Homo sapiens 152-162 25750456-3 2015 Mass Spectrometry (MS) has evolved as one of the most powerful tools in glycomics and glycoproteomics and in combination with porous graphitized carbon-liquid chromatography (PGC-LC) it is a versatile and sensitive technique for the analysis of glycans and to some extent also glycopeptides. Glycopeptides 277-290 progastricsin Homo sapiens 175-178 25750456-8 2015 In addition, we will briefly review PGC analysis approaches for glycopeptides, glycosaminoglycans (GAGs) and human milk oligosaccharides (HMOs). Glycopeptides 64-77 progastricsin Homo sapiens 36-39 25265424-6 2014 Core fucosylation is detectable in only trace amounts in haptoglobin but with confidence on hemopexin and complement factor H, where core fucosylation of the bi-antennary glycans on select glycopeptides reaches 15-20% intensity. Glycopeptides 189-202 complement factor H Homo sapiens 106-125 25691903-13 2015 Sinus mucin fragmentation produced mucin subunits and glycopeptide units of smaller molecular sizes which are likely to have lower viscoelastic properties. Glycopeptides 54-66 LOC100508689 Homo sapiens 6-11 25665441-8 2015 In addition, results on deglycosylation of metabolically labeled cathepsin Z are shown and the alterations in the apparent size of the glycopeptides are explained. Glycopeptides 135-148 cathepsin Z Homo sapiens 65-76 26156539-5 2015 Sulfated polysaccharides/glycopeptides and flavonoids may have synergistic effects with targeted anti-angiogenic drugs mainly targeting VEGF pathway by inhibiting bFGF and HIF-1alpha pathway, respectively. Glycopeptides 25-38 vascular endothelial growth factor A Homo sapiens 136-140 26156539-5 2015 Sulfated polysaccharides/glycopeptides and flavonoids may have synergistic effects with targeted anti-angiogenic drugs mainly targeting VEGF pathway by inhibiting bFGF and HIF-1alpha pathway, respectively. Glycopeptides 25-38 fibroblast growth factor 2 Homo sapiens 163-167 26156539-5 2015 Sulfated polysaccharides/glycopeptides and flavonoids may have synergistic effects with targeted anti-angiogenic drugs mainly targeting VEGF pathway by inhibiting bFGF and HIF-1alpha pathway, respectively. Glycopeptides 25-38 hypoxia inducible factor 1 subunit alpha Homo sapiens 172-182 25329175-0 2014 Synthesis aided structural determination of amyloid-beta(1-15) glycopeptides, new biomarkers for Alzheimer"s disease. Glycopeptides 63-76 amyloid beta precursor protein Homo sapiens 44-56 25329175-2 2014 Aided by these glycopeptides and tandem mass spectrometry analysis, the naturally existing amyloid-beta glycopeptides, isolated from Alzheimer"s disease patients, were determined to contain an alpha-linked N-acetyl galactosamine at the modified tyrosine 10 residue. Glycopeptides 15-28 amyloid beta precursor protein Homo sapiens 91-103 24957836-1 2014 Glycopeptides are known to select for heterogeneous vancomycin-intermediate Staphylococcus aureus (h-VISA) from susceptible strains. Glycopeptides 0-13 mitochondrial antiviral signaling protein Homo sapiens 101-105 25324212-0 2014 Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin. Glycopeptides 119-132 LOC100508689 Homo sapiens 113-118 25324212-0 2014 Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin. Glycopeptides 119-132 C-type lectin domain containing 10A Homo sapiens 146-178 25324212-2 2014 NMR and modeling-based data on the molecular recognition features of synthetic Tn-bearing glycopeptides by MGL are presented. Glycopeptides 90-103 C-type lectin domain containing 10A Homo sapiens 107-110 25303614-4 2014 We tested a small library consisting of 27 MUC1 glycopeptides with different O-glycosylations against anti-MUC1 mAb clone VU-3C6. Glycopeptides 48-61 mucin 1, cell surface associated Homo sapiens 43-47 25303614-4 2014 We tested a small library consisting of 27 MUC1 glycopeptides with different O-glycosylations against anti-MUC1 mAb clone VU-3C6. Glycopeptides 48-61 mucin 1, cell surface associated Homo sapiens 107-111 25092234-7 2014 Analysis of hFXI glycopeptides by LC-MS/MS enabled site-specific glycan profiling and occupancy. Glycopeptides 17-30 coagulation factor XI Homo sapiens 12-16 24957836-2 2014 In certain clinical situations, h-VISA strains have been isolated from patients without previous exposure to glycopeptides, such as cystic fibrosis patients, who frequently receive repeated treatments with beta-lactam antibiotics. Glycopeptides 109-122 mitochondrial antiviral signaling protein Homo sapiens 34-38 24884609-5 2014 First, we confirmed that the four ITIH4 N-X-S/T sequons (N81, N207, N517, and N577) were glycosylated by treating ITIH4 tryptic/GluC glycopeptides with PNGaseF in the presence of (18)O water. Glycopeptides 133-146 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 34-39 24884609-5 2014 First, we confirmed that the four ITIH4 N-X-S/T sequons (N81, N207, N517, and N577) were glycosylated by treating ITIH4 tryptic/GluC glycopeptides with PNGaseF in the presence of (18)O water. Glycopeptides 133-146 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 114-119 24884609-5 2014 First, we confirmed that the four ITIH4 N-X-S/T sequons (N81, N207, N517, and N577) were glycosylated by treating ITIH4 tryptic/GluC glycopeptides with PNGaseF in the presence of (18)O water. Glycopeptides 133-146 glucosylceramidase beta 3 (gene/pseudogene) Homo sapiens 128-132 24645849-3 2014 From libraries of ~10(13) glycopeptides containing multiple Man9 glycan(s), we selected variants that bind to HIV broadly neutralizing antibody 2G12 with picomolar to low nanomolar affinity. Glycopeptides 26-39 mannosidase alpha class 1A member 1 Homo sapiens 60-64 24576160-0 2014 Can amphipathic helices influence the CNS antinociceptive activity of glycopeptides related to beta-endorphin? Glycopeptides 70-83 proopiomelanocortin Homo sapiens 95-109 25635161-7 2014 RESULTS: MS/MS analysis of glycopeptides captured from BxPC-3 cells revealed 18 proteins predicted or known to be associated with the plasma membrane, including CD109, which has not been reported in pancreatic cancer. Glycopeptides 27-40 CD109 molecule Homo sapiens 161-166 24246952-0 2014 A straightforward protocol for the preparation of high performance microarray displaying synthetic MUC1 glycopeptides. Glycopeptides 104-117 mucin 1, cell surface associated Homo sapiens 99-103 24246952-4 2014 RESULTS: Selective imine-coupling between aminooxy-functionalized methacrylic copolymer with phosphorylcholine unit and synthetic MUC1 glycopeptides-capped by a ketone linker at N-terminus provided a facile and seamless protocol for the preparation of glycopeptides microarray platform. Glycopeptides 135-148 mucin 1, cell surface associated Homo sapiens 130-134 24246952-4 2014 RESULTS: Selective imine-coupling between aminooxy-functionalized methacrylic copolymer with phosphorylcholine unit and synthetic MUC1 glycopeptides-capped by a ketone linker at N-terminus provided a facile and seamless protocol for the preparation of glycopeptides microarray platform. Glycopeptides 252-265 mucin 1, cell surface associated Homo sapiens 130-134 24393138-0 2014 Glycan analysis of Prostate Specific Antigen (PSA) directly from the intact glycoprotein by HR-ESI/TOF-MS. Glycans are important modulators of the biological function of proteins and are normally characterized from proteolytic glycopeptides or from (N-)glycans released enzymatically by glycosidase treatment or chemically by hydrazinolysis. Glycopeptides 227-240 kallikrein related peptidase 3 Homo sapiens 46-49 24239874-3 2014 In order to study how glycogenin-1 and -2 interactions may influence each other"s glucosylations we setup a cell-free expression system for in vitro production and glucosylation of glycogenin-1 and -2 in various combinations, and used a mass spectrometry based workflow for the characterization and quantitation of tryptic glycopeptides originating from glycogenin-1 and -2. Glycopeptides 323-336 glycogenin 1 Homo sapiens 22-41 24164404-5 2013 Here, we show the feasibility of formerly N-glycopeptide identification and quantification at MS1 level using genomic N-glycosite prediction (GenoGlyco) coupled with stable isotopic labeling and accurate mass matching. Glycopeptides 44-56 MS Homo sapiens 94-97 24307362-0 2013 A unified strategy for the synthesis of mucin cores 1-4 saccharides and the assembled multivalent glycopeptides. Glycopeptides 98-111 LOC100508689 Homo sapiens 40-45 24123641-6 2013 A site-specific glycoform profile variation was obtained by comparing the glycoform profile of CH2 and 13 CD2 glycopeptides. Glycopeptides 110-123 CD2 molecule Homo sapiens 106-109 23909558-7 2013 By implementing the rules into an algorithm to score potential assignments against ETD-MS/MS data, we applied the method to glycopeptides generated from various O-glycosylated proteins including mucin, erythropoietin, fetuin, and an HIV envelope protein, 1086.C gp120. Glycopeptides 124-137 LOC100508689 Homo sapiens 195-200 24160308-2 2013 These glycosylamino acids can be employed directly in the solid-phase synthesis of glycopeptides, as demonstrated by the efficient preparation of tumor-associated MUC1 glycopeptide fragments. Glycopeptides 83-96 mucin 1, cell surface associated Homo sapiens 163-167 24097394-7 2013 LC/ETD was also performed on ions from the smaller glycopeptides obtained from erythropoietin. Glycopeptides 51-64 erythropoietin Homo sapiens 79-93 23912193-6 2013 Fmoc-solid phase peptide synthesis was carried out using COMU as the coupling reagent for the introduction of [Hyp(L-Araf0-3)] derivatives as well as further elongation to the CLV3 glycopeptides. Glycopeptides 181-194 CLAVATA3 Arabidopsis thaliana 176-180 23909558-7 2013 By implementing the rules into an algorithm to score potential assignments against ETD-MS/MS data, we applied the method to glycopeptides generated from various O-glycosylated proteins including mucin, erythropoietin, fetuin, and an HIV envelope protein, 1086.C gp120. Glycopeptides 124-137 erythropoietin Homo sapiens 202-216 23909558-7 2013 By implementing the rules into an algorithm to score potential assignments against ETD-MS/MS data, we applied the method to glycopeptides generated from various O-glycosylated proteins including mucin, erythropoietin, fetuin, and an HIV envelope protein, 1086.C gp120. Glycopeptides 124-137 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 262-267 23535562-0 2013 One-pot multi-enzyme (OPME) chemoenzymatic synthesis of sialyl-Tn-MUC1 and sialyl-T-MUC1 glycopeptides containing natural or non-natural sialic acid. Glycopeptides 89-102 mucin 1, cell surface associated Homo sapiens 84-88 23535562-1 2013 A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. Glycopeptides 33-46 eukaryotic translation elongation factor 1 alpha 2 Homo sapiens 12-15 23535562-1 2013 A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. Glycopeptides 33-46 mucin 1, cell surface associated Homo sapiens 28-32 23535562-1 2013 A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. Glycopeptides 33-46 mucin 1, cell surface associated Homo sapiens 28-32 23535562-1 2013 A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. Glycopeptides 33-45 eukaryotic translation elongation factor 1 alpha 2 Homo sapiens 12-15 23535562-1 2013 A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. Glycopeptides 33-45 mucin 1, cell surface associated Homo sapiens 28-32 23535562-1 2013 A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. Glycopeptides 33-45 mucin 1, cell surface associated Homo sapiens 28-32 23732560-0 2013 Convergent synthesis of MUC1 glycopeptides via serine ligation. Glycopeptides 29-42 mucin 1, cell surface associated Homo sapiens 24-28 23829323-9 2013 We further demonstrate the effectiveness of this approach by analyzing plasma-derived haptoglobin, identifying 136 N-linked glycopeptide spectra at a false discovery rate of 0.4%, representing 15 distinct glycopeptides on at least three of the four N-linked glycosylation sites. Glycopeptides 205-218 haptoglobin Homo sapiens 86-97 23831758-3 2013 We report here the design, synthesis and antigenic evaluation of new cyclic V1V2 glycopeptides carrying defined N-linked glycans at the conserved glycosylation sites (Asn160 and Asn156 or Asn173) derived from gp120 of two HIV-1 isolates. Glycopeptides 81-94 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 209-214 23732560-1 2013 Syntheses of MUC1 glycopeptides (40-mer and 80-mer) are described. Glycopeptides 18-31 mucin 1, cell surface associated Homo sapiens 13-17 23616304-0 2013 Self-adjuvanting synthetic antitumor vaccines from MUC1 glycopeptides conjugated to T-cell epitopes from tetanus toxoid. Glycopeptides 56-69 mucin 1, cell surface associated Homo sapiens 51-55 23676437-2 2013 A cluster of genes homologous to enterococcal glycopeptides resistance vanG genes was found in the genome of C. difficile 630, although this strain remains sensitive to vancomycin. Glycopeptides 46-59 D-alanine--D-serine ligase VanG-Cd Clostridioides difficile 630 71-75 23380952-6 2013 In this study, 3-AQ/CHCA LM was applied to tryptic digests of HER2 to reveal its N-glycosylation state and to evaluate the utility of this LM in characterizing glycopeptides. Glycopeptides 160-173 erb-b2 receptor tyrosine kinase 2 Homo sapiens 62-66 23652307-2 2013 As we have found autoantibodies to MUC1 glycopeptides to be elevated in early-stage breast cancer patients, in this study we analysed these autoantibodies in large population cohorts of sera taken before cancer diagnosis. Glycopeptides 40-53 mucin 1, cell surface associated Homo sapiens 35-39 23256149-6 2013 Comparison of mono-, di- and triarabinosylated CLV3 glycopeptides revealed that the biological activity increased progressively as the arabinose chain length increased. Glycopeptides 52-65 CLAVATA3 Arabidopsis thaliana 47-51 23389048-9 2013 The exoglycosidase-assisted LC-MS-MRM workflow, optimized for the quantification of fucosylated glycoforms of haptoglobin, can be used for quantification of these glycoforms on other glycopeptides with appropriate analytical behavior. Glycopeptides 183-196 haptoglobin Homo sapiens 110-121 22381366-2 2012 Synthetic cluster glycopeptides (e.g., triGalNAc) bind with high affinity to ASGP-R and, when conjugated to a therapeutic agent, can drive receptor-mediated uptake in liver. Glycopeptides 18-31 mucin 4, cell surface associated Rattus norvegicus 77-81 23280874-3 2013 A new thioether-ligation method for the synthesis of two- and three-component vaccines that contain MUC1 glycopeptides as the B-cell epitopes, a T-cell epitope peptide, and the Pam(3)CSK(4) lipopeptide is described. Glycopeptides 105-118 mucin 1, transmembrane Mus musculus 100-104 23934307-0 2013 Root-derived CLE glycopeptides control nodulation by direct binding to HAR1 receptor kinase. Glycopeptides 17-30 CM0216.560.nc Lotus japonicus 71-75 23023583-6 2012 The immunogenicity of synthetic MUC1 glycopeptides bearing Tn or sialyl-Tn antigens have been studied in mouse models, while authentic glyco-epitopes expressed by tumor cells remain unclear. Glycopeptides 37-50 mucin 1, transmembrane Mus musculus 32-36 23023583-8 2012 Antibody responses to individual glyco-epitopes were determined by chemically synthesized candidate MUC1 glycopeptides predicted through computational glycomics. Glycopeptides 105-118 mucin 1, transmembrane Mus musculus 100-104 22559037-0 2012 HIV inhibition by CD4 and CCR5-derived glycopeptides. Glycopeptides 39-52 C-C motif chemokine receptor 5 Homo sapiens 26-30 22559037-10 2012 Notably, the combination of CD4 and CCR5 glycopeptides enhanced the neutralization potential as compared to the single peptides. Glycopeptides 41-54 C-C motif chemokine receptor 5 Homo sapiens 36-40 22265686-9 2012 GENERAL SIGNIFICANCE: Novel glycomics designated for investigating proteoglycan biosynthesis, namely real-time GAGomics using synthetic glycopeptides as PGIs, should facilitate greatly dynamic profiling of GAGs in the living cells. Glycopeptides 136-149 prostaglandin I2 synthase Homo sapiens 153-157 22393263-1 2012 Improved enrichment methods for mucin core-1 type glycopeptides. Glycopeptides 50-63 LOC100508689 Homo sapiens 32-37 22393263-3 2012 Bovine serum samples were subjected to lectin affinity-chromatography both at the protein- and peptide-level in order to selectively isolate glycopeptides with the most common, mucin core-1 sugar. Glycopeptides 141-154 LOC100508689 Homo sapiens 177-182 22678432-2 2012 This protocol describes workflows for the characterization of glycopeptides and their site-specific heterogeneity, showing examples of the analysis of recombinant human erythropoietin (rHuEPO), alpha1-proteinase inhibitor (A1PI) and immunoglobulin (IgG). Glycopeptides 62-75 erythropoietin Homo sapiens 169-183 23113753-8 2013 In a subset of patients who received initial treatment with glycopeptides, only the patients whose isolates were hVISA(+)/BIVR(+) displayed a significantly higher mortality rate in comparison to those with non-hVISA(+)/BIVR(+) (80.0% vs 31.3%, p = 0.004). Glycopeptides 60-73 mitochondrial antiviral signaling protein Homo sapiens 113-118 23113753-8 2013 In a subset of patients who received initial treatment with glycopeptides, only the patients whose isolates were hVISA(+)/BIVR(+) displayed a significantly higher mortality rate in comparison to those with non-hVISA(+)/BIVR(+) (80.0% vs 31.3%, p = 0.004). Glycopeptides 60-73 mitochondrial antiviral signaling protein Homo sapiens 210-215 23259747-0 2013 Site-specific conformational alteration induced by sialylation of MUC1 tandem repeating glycopeptides at an epitope region for the anti-KL-6 monoclonal antibody. Glycopeptides 88-101 mucin 1, cell surface associated Homo sapiens 66-70 23259747-3 2013 Systematic nuclear magnetic resonance (NMR) study revealed that sialylation of the MUC1 tandem repeating glycopeptide, Pro-Pro-Ala-His-Gly-Val-Thr-Ser-Ala-Pro-Asp-Thr-Arg-Pro-Ala-Pro-Gly-Ser-Thr-Ala with core 2-type O-glycans at five potential glycosylation sites, afforded a specific conformational change at one of the most important cancer-relevant epitopes (Pro-Asp-Thr-Arg). Glycopeptides 105-117 mucin 1, cell surface associated Homo sapiens 83-87 23943488-3 2013 This will be exemplified for mucin-type glycopeptides and the construction of glycopeptide microarrays. Glycopeptides 40-53 LOC100508689 Homo sapiens 29-34 22444368-6 2012 Features of the native mucin motifs impact their relative immunogenicity and are accurately encoded in the antibody binding site, with the conformational integrity being preserved in isolated glycopeptides, as reflected in the antibody binding profile to array components. Glycopeptides 192-205 LOC100508689 Homo sapiens 23-28 21822974-7 2012 The few cases of MR-hVISA infections evaluated in our study demonstrated that 5 out of 9 patients (55%) receiving a glycopeptide, died. Glycopeptides 116-128 mitochondrial antiviral signaling protein Homo sapiens 20-25 21780104-9 2012 In particular, fucosylation at Asn 241 of beta-Hp in sera of colon cancer patients was clearly higher than in the other groups, and the ratio of fucosylated glycopeptides containing Asn 241 decreased greatly after treatment with alpha1-3/4 fucosidase. Glycopeptides 157-170 adrenoceptor alpha 1D Homo sapiens 229-237 22042768-0 2012 Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates. Glycopeptides 147-159 polypeptide N-acetylgalactosaminyltransferase 3 Homo sapiens 69-127 22329400-8 2012 (iii) Studies of [14C] sialylated human sera showed larger mucin glycopeptides and >2-fold larger mucin-type chains in human serum compared to [14C]sialyl labeled glycans of fetuin. Glycopeptides 65-78 LOC100508689 Homo sapiens 59-64 22042768-4 2012 Here, we report a new strategy to give insight on the sugar recognition ability and the function of the GalNAc-T3 lectin domain using chemically synthesized natural-type (alpha-GalNAc-O-Thr) and unnatural-type [beta-GalNAc-O-Thr, alpha-Fuc-O-Thr and beta-GlcNAc-O-Thr] MUC5AC glycopeptides. Glycopeptides 276-289 polypeptide N-acetylgalactosaminyltransferase 3 Homo sapiens 104-113 21768105-6 2011 Using a glycopeptide array with a library of synthetic and recombinant glycopeptides based on sequences of mucins MUC1, MUC2, MUC4, MUC5AC, MUC6, and MUC7 as well as a random glycopeptide bead library, we examined the binding properties of four different lectin domains. Glycopeptides 71-84 mucin 1, cell surface associated Homo sapiens 114-118 22539431-7 2012 The rKLK6 glycoform composition of each peak was assessed by lectin affinity and MS/MS based glycopeptide quantification by product ion monitoring. Glycopeptides 93-105 kallikrein related-peptidase 6 Rattus norvegicus 4-9 22365600-3 2012 We report the molecular details of the interaction of a bacterial O-GlcNAcase homolog with three different synthetic glycopeptides derived from characterized O-GlcNAc sites in the human proteome. Glycopeptides 117-130 O-GlcNAcase Homo sapiens 66-77 22365600-3 2012 We report the molecular details of the interaction of a bacterial O-GlcNAcase homolog with three different synthetic glycopeptides derived from characterized O-GlcNAc sites in the human proteome. Glycopeptides 117-130 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 66-74 22122935-0 2012 Analysis of recombinant human erythropoietin glycopeptides by capillary electrophoresis electrospray-time of flight-mass spectrometry. Glycopeptides 45-58 erythropoietin Homo sapiens 30-44 22122935-3 2012 Neuraminidase was first used to enhance the detection of the glycopeptides and detect all possible glycoforms contained in each glycosylation site. Glycopeptides 61-74 neuraminidase 1 Homo sapiens 0-13 22081384-5 2012 All five glycopeptides contained the hydroxy-amino acids serine and threonine, suggesting that Acm2 is O-glycosylated. Glycopeptides 9-22 cell wall hydrolase Lactobacillus plantarum WCFS1 95-99 23272204-8 2012 Tryptic glycopeptides of Hpt were also analyzed by mass spectrometry, and a decreased amount of sialylated glycan chains was found in glycopeptides of skin Hpt, as compared with Hpt from plasma. Glycopeptides 134-147 haptoglobin Homo sapiens 156-159 23272204-8 2012 Tryptic glycopeptides of Hpt were also analyzed by mass spectrometry, and a decreased amount of sialylated glycan chains was found in glycopeptides of skin Hpt, as compared with Hpt from plasma. Glycopeptides 134-147 haptoglobin Homo sapiens 156-159 22253738-1 2012 Glycopeptides are still the gold standard to treat MRSA (Methicillin Resistant Staphylococcus aureus) infections, but their widespread use has led to vancomycin-reduced susceptibility [heterogeneous Vancomycin-Intermediate-Staphylococcus aureus (hVISA) and Vancomycin-Intermediate-Staphylococcus aureus (VISA)], in which different genetic loci (regulatory, autolytic, cell-wall turnover and cell-envelope positive charge genes) are involved. Glycopeptides 0-13 mitochondrial antiviral signaling protein Homo sapiens 246-251 22253738-1 2012 Glycopeptides are still the gold standard to treat MRSA (Methicillin Resistant Staphylococcus aureus) infections, but their widespread use has led to vancomycin-reduced susceptibility [heterogeneous Vancomycin-Intermediate-Staphylococcus aureus (hVISA) and Vancomycin-Intermediate-Staphylococcus aureus (VISA)], in which different genetic loci (regulatory, autolytic, cell-wall turnover and cell-envelope positive charge genes) are involved. Glycopeptides 0-13 mitochondrial antiviral signaling protein Homo sapiens 247-251 22180206-8 2011 This study demonstrates the capabilities of ETD MS/MS for site-specific characterisation of mucin-type glycopeptides containing high-density O-linked glycan clusters, using accessible and relative low-resolution/low-mass accuracy IT MS instrumentation. Glycopeptides 103-116 LOC100508689 Homo sapiens 92-97 21898809-3 2011 A new method was developed to selectively enrich glycopeptides from complex sample by coupling C18 fractionation with titanium dioxide (TiO(2)) enrichment. Glycopeptides 49-62 Bardet-Biedl syndrome 9 Homo sapiens 95-98 21959619-6 2011 CONCLUSIONS: The thickened nerve fiber layer was probably caused by accumulation of metabolic products such as sialylated oligosaccharides and glycopeptides, suggesting that SD- OCT, due to its enhanced resolution, can be a useful tool for diagnosis of rare neurological conditions. Glycopeptides 143-156 plexin A2 Homo sapiens 178-181 21880669-2 2012 KL-6/mAb is thought to recognize the specific glycopeptides sequence of MUC1, but the precise glycan structure of the epitope is unclear. Glycopeptides 46-59 mucin 1, cell surface associated Homo sapiens 0-8 21880669-2 2012 KL-6/mAb is thought to recognize the specific glycopeptides sequence of MUC1, but the precise glycan structure of the epitope is unclear. Glycopeptides 46-59 mucin 1, cell surface associated Homo sapiens 72-76 22970605-3 2012 Copeptin is a glycopeptide of 39 amino acid residues that is cleaved from a precursor of ADH and secreted to the circulation in an equimolar manner with ADH. Glycopeptides 14-26 arginine vasopressin Homo sapiens 0-8 22970605-3 2012 Copeptin is a glycopeptide of 39 amino acid residues that is cleaved from a precursor of ADH and secreted to the circulation in an equimolar manner with ADH. Glycopeptides 14-26 arginine vasopressin Homo sapiens 89-92 22970605-3 2012 Copeptin is a glycopeptide of 39 amino acid residues that is cleaved from a precursor of ADH and secreted to the circulation in an equimolar manner with ADH. Glycopeptides 14-26 arginine vasopressin Homo sapiens 153-156 22259131-1 2012 The characterization of mucin-type O-glycosylation is fraught with extreme difficulty at almost every level of analysis: from difficulties in obtaining glycopeptides suitable for study, their structural heterogeneity, lack of broad acting glycosidase tools capable of simplifying the glycans, and finally the vast complexity of performing analysis on multiply glycosylated glycopeptides. Glycopeptides 152-165 LOC100508689 Homo sapiens 24-29 22259131-1 2012 The characterization of mucin-type O-glycosylation is fraught with extreme difficulty at almost every level of analysis: from difficulties in obtaining glycopeptides suitable for study, their structural heterogeneity, lack of broad acting glycosidase tools capable of simplifying the glycans, and finally the vast complexity of performing analysis on multiply glycosylated glycopeptides. Glycopeptides 373-386 LOC100508689 Homo sapiens 24-29 23272204-8 2012 Tryptic glycopeptides of Hpt were also analyzed by mass spectrometry, and a decreased amount of sialylated glycan chains was found in glycopeptides of skin Hpt, as compared with Hpt from plasma. Glycopeptides 134-147 haptoglobin Homo sapiens 25-28 21768105-6 2011 Using a glycopeptide array with a library of synthetic and recombinant glycopeptides based on sequences of mucins MUC1, MUC2, MUC4, MUC5AC, MUC6, and MUC7 as well as a random glycopeptide bead library, we examined the binding properties of four different lectin domains. Glycopeptides 71-84 mucin 4, cell surface associated Homo sapiens 126-130 21768105-6 2011 Using a glycopeptide array with a library of synthetic and recombinant glycopeptides based on sequences of mucins MUC1, MUC2, MUC4, MUC5AC, MUC6, and MUC7 as well as a random glycopeptide bead library, we examined the binding properties of four different lectin domains. Glycopeptides 71-84 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 132-138 21768105-7 2011 The lectin domains of GalNAc-T1, -T2, -T3, and -T4 bound different subsets of small glycopeptides. Glycopeptides 84-97 polypeptide N-acetylgalactosaminyltransferase 1 Homo sapiens 22-31 21563953-7 2011 vanA-Enterococcus faecium isolates were recovered from 4 of 103 tested samples, and they showed glycopeptide and erythromycin resistances. Glycopeptides 96-108 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 0-4 21712440-4 2011 In addition to 33 unglycosylated APP/Abeta peptides, we identified 37 APP/Abeta glycopeptides with sialylated core 1 like O-glycans attached to Thr(-39, -21, -20, and -13), in a series of APP/AbetaX-15 glycopeptides, where X was -63, -57, -52, and -45, in relation to Asp1 of the Abeta sequence. Glycopeptides 202-215 amyloid beta precursor protein Homo sapiens 74-79 21819298-8 2011 The profiling of sera immunoreactivity of colon cancer patients allowed the identification of cancer-associated autoantibodies to various mucin (MUC)1 and MUC4 glycopeptides carrying aberrant glycosylation. Glycopeptides 160-173 mucin 4, cell surface associated Homo sapiens 155-159 21712440-4 2011 In addition to 33 unglycosylated APP/Abeta peptides, we identified 37 APP/Abeta glycopeptides with sialylated core 1 like O-glycans attached to Thr(-39, -21, -20, and -13), in a series of APP/AbetaX-15 glycopeptides, where X was -63, -57, -52, and -45, in relation to Asp1 of the Abeta sequence. Glycopeptides 80-93 amyloid beta precursor protein Homo sapiens 74-79 21712440-4 2011 In addition to 33 unglycosylated APP/Abeta peptides, we identified 37 APP/Abeta glycopeptides with sialylated core 1 like O-glycans attached to Thr(-39, -21, -20, and -13), in a series of APP/AbetaX-15 glycopeptides, where X was -63, -57, -52, and -45, in relation to Asp1 of the Abeta sequence. Glycopeptides 80-93 beta-secretase 2 Homo sapiens 268-272 21712440-4 2011 In addition to 33 unglycosylated APP/Abeta peptides, we identified 37 APP/Abeta glycopeptides with sialylated core 1 like O-glycans attached to Thr(-39, -21, -20, and -13), in a series of APP/AbetaX-15 glycopeptides, where X was -63, -57, -52, and -45, in relation to Asp1 of the Abeta sequence. Glycopeptides 202-215 amyloid beta precursor protein Homo sapiens 74-79 21712440-4 2011 In addition to 33 unglycosylated APP/Abeta peptides, we identified 37 APP/Abeta glycopeptides with sialylated core 1 like O-glycans attached to Thr(-39, -21, -20, and -13), in a series of APP/AbetaX-15 glycopeptides, where X was -63, -57, -52, and -45, in relation to Asp1 of the Abeta sequence. Glycopeptides 80-93 amyloid beta precursor protein Homo sapiens 74-79 21712440-5 2011 Unexpectedly, we also identified a series of 27 glycopeptides, the Abeta1-X series, where X was 20 (DAEFRHDSGYEVHHQKLVFF), 19, 18, 17, 16, and 15, which were all uniquely glycosylated on Tyr10. Glycopeptides 48-61 AA1 Homo sapiens 67-73 21613225-5 2011 Surprisingly, mass spectrometric analysis of LIF glycopeptides enriched on the CI-MPR column revealed that all six N-glycan sites could be Man-6-P-modified. Glycopeptides 49-62 LIF interleukin 6 family cytokine Homo sapiens 45-48 21613225-5 2011 Surprisingly, mass spectrometric analysis of LIF glycopeptides enriched on the CI-MPR column revealed that all six N-glycan sites could be Man-6-P-modified. Glycopeptides 49-62 insulin like growth factor 2 receptor Homo sapiens 79-85 19477606-9 2011 The two patients with E. faecium VanA had been previously given glycopeptides for 10 days. Glycopeptides 64-77 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 33-37 21455712-0 2011 Glycopeptide and daptomycin resistance in community-associated MRSA in the UK. Glycopeptides 0-12 solute carrier family 9 member A6 Homo sapiens 63-67 21451866-2 2011 This derivative exhibits a similar affinity for a natural lectin as for the natural Tn and retains the bioactive conformation observed in the Tn-containing glycopeptides with anti-MUC1 antibodies. Glycopeptides 156-169 mucin 1, cell surface associated Homo sapiens 180-184 21538615-0 2011 Towards a fully synthetic MUC1-based anticancer vaccine: efficient conjugation of glycopeptides with mono-, di-, and tetravalent lipopeptides using click chemistry. Glycopeptides 82-95 mucin 1, cell surface associated Homo sapiens 26-30 21538615-4 2011 These fully synthetic vaccine candidates were prepared by solid-phase synthesis of the MUC1 glycopeptides. Glycopeptides 92-105 mucin 1, cell surface associated Homo sapiens 87-91 21469647-4 2011 The strategy described herein involves the analysis of a complex mixture of glycopeptides generated from immobilized-Pronase digestion of a cocktail of glycoproteins consisting of bovine lactoferrin, kappa casein, and bovine fetuin using nanoflow liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (nano-LC-Q-TOF MS). Glycopeptides 76-89 lactotransferrin Bos taurus 187-198 20598637-1 2010 Methicillin-resistant Staphylococcus aureus (MRSA) with decreased susceptibility to glycopeptides can be categorized as first, heteroresistant to vancomycin (hVISA); second, with intermediate susceptibility to vancomycin (VISA); and third, fully resistant to vancomycin (VRSA). Glycopeptides 84-97 mitochondrial antiviral signaling protein Homo sapiens 158-163 21443200-0 2011 Elucidation of glycoprotein structures by unspecific proteolysis and direct nanoESI mass spectrometric analysis of ZIC-HILIC-enriched glycopeptides. Glycopeptides 134-147 Zic family member 1 Homo sapiens 115-118 21443200-5 2011 This method has now been refined for two aspects: (1) separation of glycopeptides by use of ZIC-HILIC SPE and (2) the use of unspecific proteases like thermolysin, elastase, or a trypsin/chymotrypsin mixture leading per se to a mass-based separation, that is, small nonglycosylated peptides and almost exclusively glycopeptides at higher m/z values. Glycopeptides 68-81 Zic family member 1 Homo sapiens 92-95 21423632-6 2011 Synthesis and biological evaluation of the designed glycopeptides provided novel structure-activity relationship (SAR) understanding of binding to A(q) and DR4. Glycopeptides 52-65 major histocompatibility complex, class II, DR beta 4 Homo sapiens 156-159 21264968-0 2011 An efficient approach for the characterization of mucin-type glycopeptides: the effect of O-glycosylation on the conformation of synthetic mucin peptides. Glycopeptides 61-74 LOC100508689 Homo sapiens 50-55 21264968-0 2011 An efficient approach for the characterization of mucin-type glycopeptides: the effect of O-glycosylation on the conformation of synthetic mucin peptides. Glycopeptides 61-74 LOC100508689 Homo sapiens 139-144 20878823-0 2010 Synthetic antitumor vaccines from tetanus toxoid conjugates of MUC1 glycopeptides with the Thomsen-Friedenreich antigen and a fluorine-substituted analogue. Glycopeptides 68-81 mucin 1, cell surface associated Homo sapiens 63-67 20823119-6 2010 To address this problem, we analyzed all glycoforms of the HR glycopeptides of a Gal-deficient IgA1 myeloma protein, mimicking the aberrant IgA1 in patients with IgAN, by use of a combination of IgA-specific proteases + trypsin and AI-ECD Fourier transform ion cyclotron resonance (FT-ICR) tandem mass spectrometry (MS/MS). Glycopeptides 62-75 immunoglobulin heavy constant alpha 1 Homo sapiens 95-99 21344374-6 2011 Seromic profiling of patients with colorectal cancer identified cancer-associated autoantibodies to a set of aberrant glycopeptides derived from MUC1 and MUC4. Glycopeptides 118-131 mucin 1, cell surface associated Homo sapiens 145-149 21344374-6 2011 Seromic profiling of patients with colorectal cancer identified cancer-associated autoantibodies to a set of aberrant glycopeptides derived from MUC1 and MUC4. Glycopeptides 118-131 mucin 4, cell surface associated Homo sapiens 154-158 20598637-1 2010 Methicillin-resistant Staphylococcus aureus (MRSA) with decreased susceptibility to glycopeptides can be categorized as first, heteroresistant to vancomycin (hVISA); second, with intermediate susceptibility to vancomycin (VISA); and third, fully resistant to vancomycin (VRSA). Glycopeptides 84-97 mitochondrial antiviral signaling protein Homo sapiens 159-163 20563275-4 2010 By incorporation of T(N)-Fmoc-beta3hThr conjugate into the 20 amino acid tandem repeat sequence of MUC1 using sequential solid-phase glycopeptide synthesis, a first example of a mixed alpha/beta-hybrid glycopeptide building block was obtained. Glycopeptides 133-145 mucin 1, cell surface associated Homo sapiens 99-103 20726594-6 2010 As proof-of-concept, we have demonstrated that MUC1 glycopeptides could be assembled and used to detect autoantibodies in vaccine-induced disease-free breast cancer patients and in patients with confirmed disease at time of diagnosis. Glycopeptides 52-65 mucin 1, cell surface associated Homo sapiens 47-51 20574591-1 2010 MUC1 glycopeptide was efficiently coupled to glycosylphosphatidylinositol (GPI) derivatives by sortase A (SrtA), verifying that SrtA can accept sterically hindered glycopeptide as substrate for ligation with GPIs. Glycopeptides 5-17 mucin 1, cell surface associated Homo sapiens 0-4 20429820-12 2010 CONCLUSION: The results of this meta-analysis suggest higher success rates for linezolid and the new glycopeptides (dalbavancin and telavancin) in MRSA-confirmed cSSTIs. Glycopeptides 101-114 solute carrier family 9 member A6 Homo sapiens 147-151 20335177-8 2010 Liquid chromatography/multiple-stage mass spectrometry analysis of Glu-C glycopeptides of each VN determined the site-specific glycosylation. Glycopeptides 73-86 vitronectin Rattus norvegicus 95-97 20563275-4 2010 By incorporation of T(N)-Fmoc-beta3hThr conjugate into the 20 amino acid tandem repeat sequence of MUC1 using sequential solid-phase glycopeptide synthesis, a first example of a mixed alpha/beta-hybrid glycopeptide building block was obtained. Glycopeptides 202-214 mucin 1, cell surface associated Homo sapiens 99-103 19819901-6 2010 The recombinant tomato PNGase showed optimum activity at pH 4.5 and 40 degrees C. It did not require any metal ions for full enzymatic activity and could release the complex-type N-glycan from glycopeptides. Glycopeptides 193-206 peptide N-glycanase Solanum lycopersicum 23-29 20209506-0 2010 Characterization of sialylated and fucosylated glycopeptides of beta2-glycoprotein I by a combination of HILIC LC and MALDI MS/MS. Glycopeptides 47-60 apolipoprotein H Homo sapiens 64-84 20415687-1 2010 AIM: To design, manufacture and test a second generation leptin receptor (ObR) agonist glycopeptide derivative. Glycopeptides 87-99 leptin Mus musculus 57-63 20816477-4 2010 Additionally, we have developed an in vivo production system for mammalian mucin-type glycopeptides using a genetically engineered yeast strain. Glycopeptides 86-99 LOC100508689 Homo sapiens 75-80 20043307-2 2010 After investigation and optimization of various surface materials, surface chemistries and reaction parameters, microstructures and microarrays of biotin, oligonucleotides, peptides, and MUC1 tandem repeat glycopeptides were prepared with this photoimmobilization method. Glycopeptides 206-219 mucin 1, transmembrane Mus musculus 187-191 20091489-2 2010 To pursue this diagnostic approach, we used mass spectrometric analysis to search for specific structures in IgA1 hinge glycopeptides in 30 IgAN patients contrasted with 30 healthy controls. Glycopeptides 120-133 immunoglobulin heavy constant alpha 1 Homo sapiens 109-113 20091489-2 2010 To pursue this diagnostic approach, we used mass spectrometric analysis to search for specific structures in IgA1 hinge glycopeptides in 30 IgAN patients contrasted with 30 healthy controls. Glycopeptides 120-133 IGAN1 Homo sapiens 140-144 20091489-11 2010 These results open the possibility for preparation of lectin and/or antibodies binding to specific glycopeptides in IgAN. Glycopeptides 99-112 IGAN1 Homo sapiens 116-120 20816484-13 2010 Here, we present examples of fluorescence-based solid-phase assays to study P- and L-selectin and galectin-1 binding to immobilized glycopeptides, oligosaccharides, and cells. Glycopeptides 132-145 selectin L Homo sapiens 83-93 20816484-13 2010 Here, we present examples of fluorescence-based solid-phase assays to study P- and L-selectin and galectin-1 binding to immobilized glycopeptides, oligosaccharides, and cells. Glycopeptides 132-145 galectin 1 Homo sapiens 98-108 19007994-2 2009 The latter results in appearance of new antigenic tumor specific glycopeptides not found on normal glycoforms of the mucin. Glycopeptides 65-78 LOC100508689 Homo sapiens 117-122 19852465-1 2009 An efficient protocol for the construction of MUC1-related glycopeptide analogues having complex O-glycan and N-glycan chains was established by integrating chemical and enzymatic approaches on the functional polymer platforms. Glycopeptides 59-71 mucin 1, cell surface associated Homo sapiens 46-50 20161377-3 2009 Here we describe new methods for the synthesis of glycopeptides that have emerged from the erythropoietin adventure, including the development of unique C-terminal acyl donors, novel amide bond forming methods, and new ligation and coupling strategies. Glycopeptides 50-63 erythropoietin Homo sapiens 91-105 19899793-4 2009 In the present study, a novel compound library of synthetic MUC1 glycopeptides allowed the first rapid and precise evaluation of the specific epitope structure of anti-KL-6 MAb by combined use of a tailored glycopeptides library and common ELISA protocol. Glycopeptides 65-78 mucin 1, cell surface associated Homo sapiens 60-64 19899793-4 2009 In the present study, a novel compound library of synthetic MUC1 glycopeptides allowed the first rapid and precise evaluation of the specific epitope structure of anti-KL-6 MAb by combined use of a tailored glycopeptides library and common ELISA protocol. Glycopeptides 65-78 mucin 1, cell surface associated Homo sapiens 168-172 19899793-4 2009 In the present study, a novel compound library of synthetic MUC1 glycopeptides allowed the first rapid and precise evaluation of the specific epitope structure of anti-KL-6 MAb by combined use of a tailored glycopeptides library and common ELISA protocol. Glycopeptides 207-220 mucin 1, cell surface associated Homo sapiens 60-64 19899793-4 2009 In the present study, a novel compound library of synthetic MUC1 glycopeptides allowed the first rapid and precise evaluation of the specific epitope structure of anti-KL-6 MAb by combined use of a tailored glycopeptides library and common ELISA protocol. Glycopeptides 207-220 mucin 1, cell surface associated Homo sapiens 168-172 19899793-10 2009 In other words, combined use of anti-KL-6 MAb and some probes that can differentiate the sugars substituted at the O-6 position of the GalNAc residue in MUC1 glycopeptides including the PDTRPAP sequence might be a promising diagnostic protocol for individual disease-specific biomarkers. Glycopeptides 158-171 mucin 1, cell surface associated Homo sapiens 37-41 19899793-10 2009 In other words, combined use of anti-KL-6 MAb and some probes that can differentiate the sugars substituted at the O-6 position of the GalNAc residue in MUC1 glycopeptides including the PDTRPAP sequence might be a promising diagnostic protocol for individual disease-specific biomarkers. Glycopeptides 158-171 mucin 1, cell surface associated Homo sapiens 153-157 19007994-4 2009 No study has yet reported presentation of MUC1 glycopeptides on MHC class I molecules as stimulators of cytotoxic T-cells. Glycopeptides 47-60 mucin 1, cell surface associated Homo sapiens 42-46 19674964-0 2009 Affinity enrichment and characterization of mucin core-1 type glycopeptides from bovine serum. Glycopeptides 62-75 LOC100508689 Homo sapiens 44-49 19007994-5 2009 In this study we show that human immunoproteasomes and cathepsin-L can generate octa to undecameric glycopeptides from the MUC1 repeat domain in vitro. Glycopeptides 100-113 cathepsin L Homo sapiens 55-66 19007994-5 2009 In this study we show that human immunoproteasomes and cathepsin-L can generate octa to undecameric glycopeptides from the MUC1 repeat domain in vitro. Glycopeptides 100-113 mucin 1, cell surface associated Homo sapiens 123-127 19524017-0 2009 Site directed processing: role of amino acid sequences and glycosylation of acceptor glycopeptides in the assembly of extended mucin type O-glycan core 2. Glycopeptides 85-98 LOC100508689 Homo sapiens 127-132 19453144-7 2009 The resulting fucosylated glycopeptides were subjected to two different runs of LC-MSn using a Fourier- transform ion cyclotron resonance mass spectrometer (FTICR-MS) and an ion trap-type mass spectrometer. Glycopeptides 26-39 moesin Mus musculus 83-86 19387707-2 2009 Compared with vancomycin-susceptible S. aureus (n = 30), hVISA and VISA infections (n = 10) are found to be associated with a longer period of prior glycopeptide use (P = 0.01), bone/joint (P < 0.01) and prosthetic infections (P = 0.04), as well as treatment failure, as evidenced by longer bacteremic (P < 0.01) and culture positivity (P < 0.01) periods. Glycopeptides 149-161 mitochondrial antiviral signaling protein Homo sapiens 57-62 19387707-2 2009 Compared with vancomycin-susceptible S. aureus (n = 30), hVISA and VISA infections (n = 10) are found to be associated with a longer period of prior glycopeptide use (P = 0.01), bone/joint (P < 0.01) and prosthetic infections (P = 0.04), as well as treatment failure, as evidenced by longer bacteremic (P < 0.01) and culture positivity (P < 0.01) periods. Glycopeptides 149-161 mitochondrial antiviral signaling protein Homo sapiens 58-62 19426130-7 2009 We conclude that MUC1 glycopeptides induce stronger immunity in MUC1-Tg mice because they are recognized as "foreign" rather than ;self" and because they are cross-presented preferentially by DCs. Glycopeptides 22-35 mucin 1, transmembrane Mus musculus 17-21 19426130-7 2009 We conclude that MUC1 glycopeptides induce stronger immunity in MUC1-Tg mice because they are recognized as "foreign" rather than ;self" and because they are cross-presented preferentially by DCs. Glycopeptides 22-35 mucin 1, transmembrane Mus musculus 64-68 19129245-6 2009 More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP. Glycopeptides 100-113 myelin basic protein Homo sapiens 88-91 19203595-1 2009 Determination of O-glycosylation sites in glycopeptides was developed by using two model compounds designed from mucin2 tandem repeat motif and erythropoietin. Glycopeptides 42-55 mucin 2, oligomeric mucus/gel-forming Homo sapiens 113-119 19129245-6 2009 More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP. Glycopeptides 100-113 myelin basic protein Homo sapiens 88-91 19088067-7 2009 After transfection in COS7 cells, the three FUT10s and at least one FUT11, link alpha-l-fucose onto conalbumin glycopeptides and biantennary N-glycan acceptors but not onto short lactosaminyl acceptor substrates as do classical monoexonic alpha1,3-fucosyltransferases. Glycopeptides 111-124 fucosyltransferase 11 Homo sapiens 68-73 19244429-1 2009 nov., a glycopeptide-resistant species isolated from human faeces. Glycopeptides 8-20 cellular communication network factor 3 Homo sapiens 0-3 19236026-1 2009 This paper reports the synthesis of a 40-residue glycopeptide having two antigenic sialyl-T(N) (NeuAc-alpha-(2,6)-GalNAc-Thr) residues in the MUC1 sequence. Glycopeptides 49-61 mucin 1, cell surface associated Homo sapiens 142-146 19074376-2 2009 In their free-living state, S. meliloti and B. abortus mutants lacking BacA have reductions in their outer membrane lipid A very-long-chain fatty acid (VLCFA) contents and exhibit low-level resistance to the glycopeptide bleomycin in comparison to their respective parent strains. Glycopeptides 208-220 putative udecaprenol kinase BacA Escherichia coli 71-75 19180724-0 2008 The interaction of mannose binding lectin (MBL) with mannose containing glycopeptides and the resultant potential impact on invasive fungal infection. Glycopeptides 72-85 mannose-binding lectin (protein C) 2 Mus musculus 43-46 19099505-2 2009 To assess the reliability of this method for determining the fucosylation levels of glycoproteins, we conducted mass spectrometry of fucosylated glycopeptides from transferrin and haptoglobin. Glycopeptides 145-158 transferrin Homo sapiens 164-175 19099505-3 2009 The biantennary glycans containing antenna alpha1,3/4 fucose or alpha1,6 core fucose showed different fragmentation behaviors in collision-induced dissociation of protonated glycopeptides. Glycopeptides 174-187 adrenoceptor alpha 1D Homo sapiens 43-51 19099505-3 2009 The biantennary glycans containing antenna alpha1,3/4 fucose or alpha1,6 core fucose showed different fragmentation behaviors in collision-induced dissociation of protonated glycopeptides. Glycopeptides 174-187 adrenoceptor alpha 1D Homo sapiens 64-72 19099505-9 2009 The mass spectrometric profiling of glycopeptides from transferrin of congenital disorders of glycosylation (CDG-Ia and CDG-IIc) patients demonstrated that the elevation or reduction of fucosylation in pathological conditions can be reliably determined by MS of glycopeptides. Glycopeptides 36-49 transferrin Homo sapiens 55-66 18220508-6 2008 We also describe a new experimental vaccine model for the generation of CD8+ cytotoxic T cells (CTL) that involves designer TACA-containing glycopeptides with high affinity for class I molecules of the major histocompatibility complex (MHC). Glycopeptides 140-153 CD8a molecule Homo sapiens 72-75 18562306-4 2008 We demonstrate that the lectin domain of hT2 directs glycosylation site selection for glycopeptide substrates. Glycopeptides 86-98 solute carrier family 25 member 5 Homo sapiens 41-44 18563860-7 2008 The technique described herein provides a mean to detect glycopeptides from commercially available pharmaceutical preparations of rhEPO with the sensitivity required to analyze pmol amounts of hEPO, which could ultimately lead to the identification of structural differences between the recombinant and the human forms of the hormone. Glycopeptides 57-70 erythropoietin Homo sapiens 131-135 18272656-6 2008 We verified this approach with the 150 serotransferrin glycopeptide spectra, where we automatically generated 10(5) putative interpretations from >10(9) theoretical glycopeptides. Glycopeptides 168-181 transferrin Homo sapiens 39-54 18683685-12 2008 Twelve vancomycin-resistant Enterococcus faecium isolates showed incongruence between phenotype and genotype for glycopeptides resistance (vanA genotype and vanB phenotype). Glycopeptides 113-126 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 139-143 18178603-7 2008 Furthermore, we examined the O-glycan structure of IgA1 hinge glycopeptides by mass spectrometry (MS). Glycopeptides 62-75 immunoglobulin heavy constant alpha 1 Homo sapiens 51-55 18178603-11 2008 MS showed that peak distribution of IgA1 hinge glycopeptides was shifted to smaller molecular weights in high HAA-IgA-binding IgAN patients. Glycopeptides 47-60 immunoglobulin heavy constant alpha 1 Homo sapiens 36-40 18178603-11 2008 MS showed that peak distribution of IgA1 hinge glycopeptides was shifted to smaller molecular weights in high HAA-IgA-binding IgAN patients. Glycopeptides 47-60 IGAN1 Homo sapiens 126-130 17592722-12 2007 It was shown that the presence of Fbs1 perturb the activity of PNGase toward high-mannose-type glycopeptides. Glycopeptides 95-108 F-box protein 2 Homo sapiens 34-38 17766267-8 2007 The improved enzyme CgtB(OH4384)DeltaC-MalE was used to galactosylate a glyco-peptide acceptor based on the interferon alpha2b protein O-linked glycosylation site as confirmed by the CE-MS analysis of the reaction products. Glycopeptides 72-85 interferon alpha 2 Homo sapiens 108-126 17960575-5 2007 Glycopeptides derived from all three N-glycosylation sites of FETUA were observed, and the corresponding CID spectra proved the respective glycans to be oligosaccharides of the triantennary complex type. Glycopeptides 0-13 alpha 2-HS glycoprotein Homo sapiens 62-67 17960575-7 2007 An in-solution tryptic/chymotryptic digest of human transferrin (TRFE) was analyzed directly for glycopeptides subsequent to the addition of methanol and formic acid. Glycopeptides 97-110 transferrin Homo sapiens 52-63 17960575-7 2007 An in-solution tryptic/chymotryptic digest of human transferrin (TRFE) was analyzed directly for glycopeptides subsequent to the addition of methanol and formic acid. Glycopeptides 97-110 transferrin Homo sapiens 65-69 17960575-8 2007 Disialylated diantennary glycans were observed in glycopeptides of both N-glycosylation sites of TRFE. Glycopeptides 50-63 transferrin Homo sapiens 97-101 17720138-3 2007 Inspection of the NMR data obtained by use of the isotopically labeled glycopeptide indicated that Fbs1 interacts with sugar-peptide junctions, which are shielded in native glycoprotein, in many cases, but become accessible to Fbs1 in unfolded glycoproteins. Glycopeptides 71-83 fibrosin Homo sapiens 99-103 17602511-6 2007 We showed by confocal microscopy and flow cytometry that fluorescent-labeled Melan-A glycoclusters containing either dimannoside or Lewis oligosaccharide were taken up by DC and concentrated in acidic vesicles; conversely lactoside glycopeptides were not at all taken up. Glycopeptides 232-245 melan-A Homo sapiens 77-84 17804752-4 2007 Glycopeptides corresponding to three tandem repeats of MUC1, enzymatically glycosylated with 9 or 15 mol of GalNAc, were shown to specifically bind and to be internalized by immature monocyte-derived DCs (iDCs). Glycopeptides 0-13 mucin 1, cell surface associated Homo sapiens 55-59 17804752-7 2007 Confocal analysis and ELISA done on subcellular fractions of iDCs showed that the Tn-MUC1 glycopeptides colocalized with HLA class I and II compartments after internalization. Glycopeptides 90-103 mucin 1, cell surface associated Homo sapiens 85-89 17956937-3 2008 In the present study, the glycan profiles of free and complexed forms of PSA from cancer patient serum and of seminal plasma PSA were compared by analyzing the glycopeptides obtained by lysylendopeptidase digestion of the electrophoretically separated PSA with mass spectrometry. Glycopeptides 160-173 kallikrein related peptidase 3 Homo sapiens 73-76 17712550-5 2007 Here, we report the analysis of IgA1 O-glycan heterogeneity by use of FT-ICR MS and liquid chromatography FT-ICR MS to obtain unbiased accurate mass profiles of IgA1 HR glycopeptides from three different IgA1 myeloma proteins. Glycopeptides 169-182 immunoglobulin heavy constant alpha 1 Homo sapiens 32-36 17712550-5 2007 Here, we report the analysis of IgA1 O-glycan heterogeneity by use of FT-ICR MS and liquid chromatography FT-ICR MS to obtain unbiased accurate mass profiles of IgA1 HR glycopeptides from three different IgA1 myeloma proteins. Glycopeptides 169-182 immunoglobulin heavy constant alpha 1 Homo sapiens 161-165 17712550-5 2007 Here, we report the analysis of IgA1 O-glycan heterogeneity by use of FT-ICR MS and liquid chromatography FT-ICR MS to obtain unbiased accurate mass profiles of IgA1 HR glycopeptides from three different IgA1 myeloma proteins. Glycopeptides 169-182 immunoglobulin heavy constant alpha 1 Homo sapiens 161-165 17513023-6 2007 At the same time, intermediate sensitive and resistant MRSA strains to glycopeptides appeared. Glycopeptides 71-84 solute carrier family 9 member A6 Homo sapiens 55-59 17592722-12 2007 It was shown that the presence of Fbs1 perturb the activity of PNGase toward high-mannose-type glycopeptides. Glycopeptides 95-108 N-glycanase 1 Homo sapiens 63-69 17295374-0 2007 Synthetic glycopeptides from the E-selectin ligand 1 with varied sialyl Lewis(x) structure as cell-adhesion inhibitors of E-selectin. Glycopeptides 10-23 golgi glycoprotein 1 Homo sapiens 33-52 17623277-7 2007 Glycosylation site and oligosaccharide structures were elucidated from MS and MS/MS spectra of trypsin-digested DCE glycopeptides. Glycopeptides 116-129 24-dehydrocholesterol reductase Homo sapiens 112-115 17623277-13 2007 During mass spectrometric analysis of DCE glycopeptides, their CID patterns were highly intriguing, in that some glycopeptides underwent both C-terminal rearrangement and formation of dimeric structures during CID. Glycopeptides 42-55 24-dehydrocholesterol reductase Homo sapiens 38-41 17623277-13 2007 During mass spectrometric analysis of DCE glycopeptides, their CID patterns were highly intriguing, in that some glycopeptides underwent both C-terminal rearrangement and formation of dimeric structures during CID. Glycopeptides 113-126 24-dehydrocholesterol reductase Homo sapiens 38-41 17502600-4 2007 To better understand the bactericidal mechanism of PGRPs, we determined the crystal structure of the C-terminal PGN-binding domain of human PGRP-I beta in complex with NAG-NAM-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala, a synthetic glycopeptide comprising a complete PGN repeat. Glycopeptides 225-237 SPG7 matrix AAA peptidase subunit, paraplegin Homo sapiens 112-115 17502600-4 2007 To better understand the bactericidal mechanism of PGRPs, we determined the crystal structure of the C-terminal PGN-binding domain of human PGRP-I beta in complex with NAG-NAM-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala, a synthetic glycopeptide comprising a complete PGN repeat. Glycopeptides 225-237 peptidoglycan recognition protein 4 Homo sapiens 140-151 17330941-11 2007 We show that analysis by cysteine-containing glycopeptides allows detection of low-abundance proteins such as the epidermal growth factor receptor, the Vitamin K-dependent protein Z, the hepatocyte growth factor activator, and the lymphatic endothelium-specific hyaluronan receptor as these proteins were not detected in the glycopeptide control analysis. Glycopeptides 45-58 epidermal growth factor receptor Mus musculus 114-146 17330941-11 2007 We show that analysis by cysteine-containing glycopeptides allows detection of low-abundance proteins such as the epidermal growth factor receptor, the Vitamin K-dependent protein Z, the hepatocyte growth factor activator, and the lymphatic endothelium-specific hyaluronan receptor as these proteins were not detected in the glycopeptide control analysis. Glycopeptides 45-58 protein Z, vitamin K-dependent plasma glycoprotein Mus musculus 152-181 17330941-11 2007 We show that analysis by cysteine-containing glycopeptides allows detection of low-abundance proteins such as the epidermal growth factor receptor, the Vitamin K-dependent protein Z, the hepatocyte growth factor activator, and the lymphatic endothelium-specific hyaluronan receptor as these proteins were not detected in the glycopeptide control analysis. Glycopeptides 45-58 hepatocyte growth factor activator Mus musculus 187-221 17400357-1 2007 In the present study the structures of two glycopeptides (G1 and G1"), isolated from FU RvH(1)-b and two glycopeptides (G2 and G3), isolated from the structural subunit RvH(1) of Rapana venosa hemocyanin, were determined. Glycopeptides 43-56 proline rich protein BstNI subfamily 3 Homo sapiens 58-68 17283034-1 2007 OBJECTIVES AND METHODS: The transferability of vanA and vanB glycopeptide resistance determinants with a defined plasmid (n = 9) or chromosomal (n = 4) location between Enterococcus faecium strains of human and animal origins was compared using filter mating (in vitro) and germ-free mice (in vivo) as experimental models. Glycopeptides 61-73 D-alanine--D-lactate ligase Enterococcus faecium 56-60 17050588-4 2007 Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycopeptides 54-67 mucin 1, transmembrane Mus musculus 49-53 17050588-4 2007 Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycopeptides 54-67 mucin 1, transmembrane Mus musculus 96-100 17050588-8 2007 In the present study, we define the immunodominant epitope on Tn/STn-MUC1 glycopeptides to the region including the amino acids GSTA of the MUC1 20-amino acid tandem repeat (HGVTSAPDTRPAPGSTAPPA). Glycopeptides 74-87 mucin 1, transmembrane Mus musculus 69-73 17050588-8 2007 In the present study, we define the immunodominant epitope on Tn/STn-MUC1 glycopeptides to the region including the amino acids GSTA of the MUC1 20-amino acid tandem repeat (HGVTSAPDTRPAPGSTAPPA). Glycopeptides 74-87 mucin 1, transmembrane Mus musculus 140-144 17194161-5 2007 On-line digestion allowed extensive cleavage of the model protein (ribonuclease B), yielding to glycopeptides with peptide moieties up to eight amino acids, carrying the Man5-Man9 N-glycans each, selectively resolved on an Amide-80 column. Glycopeptides 96-109 mannosidase alpha class 1A member 1 Homo sapiens 175-179 17295374-0 2007 Synthetic glycopeptides from the E-selectin ligand 1 with varied sialyl Lewis(x) structure as cell-adhesion inhibitors of E-selectin. Glycopeptides 10-23 selectin E Homo sapiens 33-43 16940100-9 2006 In summary, hVISA/VISA arises from fully VSSA during persistent infection that fails to respond to glycopeptide therapy and is associated with significant phenotypic changes, including a marked reduction in biofilm-forming ability. Glycopeptides 99-111 mitochondrial antiviral signaling protein Homo sapiens 12-17 17604678-5 2007 MUC16 from NHBE cells was a high-molecular-mass, monomeric mucin which gave rise to large glycopeptides after proteolysis. Glycopeptides 90-103 mucin 16, cell surface associated Homo sapiens 0-5 17604678-5 2007 MUC16 from NHBE cells was a high-molecular-mass, monomeric mucin which gave rise to large glycopeptides after proteolysis. Glycopeptides 90-103 LOC100508689 Homo sapiens 59-64 16940100-9 2006 In summary, hVISA/VISA arises from fully VSSA during persistent infection that fails to respond to glycopeptide therapy and is associated with significant phenotypic changes, including a marked reduction in biofilm-forming ability. Glycopeptides 99-111 mitochondrial antiviral signaling protein Homo sapiens 13-17 16470771-1 2006 An array of sugar oxazolines was synthesized and tested as donor substrates for the Arthrobacter endo-beta-N-acetylglucosaminidase (Endo-A)-catalyzed glycopeptide synthesis. Glycopeptides 150-162 endo-beta-N-acetylglucosaminidase Homo sapiens 97-130 17017874-0 2006 Synthetic glycopeptides from the mucin family as potential tools in cancer immunotherapy. Glycopeptides 10-23 LOC100508689 Homo sapiens 33-38 17017874-9 2006 In this review, methodologies for the synthesis of mucin-type glycopeptides containing complex tumor-associated antigen structures are described. Glycopeptides 62-75 LOC100508689 Homo sapiens 51-56 16642533-8 2006 Taken together, the joined sequence GVTSAPDTR represents the largest structural model of MUC1 derived glycopeptides analyzed so far. Glycopeptides 102-115 mucin 1, cell surface associated Homo sapiens 89-93 16599599-0 2006 Construction of highly glycosylated mucin-type glycopeptides based on microwave-assisted solid-phase syntheses and enzymatic modifications. Glycopeptides 47-60 LOC100508689 Homo sapiens 36-41 16467946-0 2006 Formation of lactones from sialylated MUC1 glycopeptides. Glycopeptides 43-56 mucin 1, cell surface associated Homo sapiens 38-42 16506767-6 2006 Beautifully, 5 exhibited antimicrobial activity (MIC = 31 microg/mL) against a VanA-resistant organism that remodels its D-Ala-D-Ala cell wall precursor to d-Ala-d-Lac upon glycopeptide antibiotic challenge, displaying a potency that reflects these binding characteristics. Glycopeptides 173-185 lactase Homo sapiens 164-167 16207894-0 2006 Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycopeptides 54-67 eukaryotic translation elongation factor 1 alpha 2 Homo sapiens 45-48 16207894-0 2006 Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycopeptides 54-67 mucin 1, cell surface associated Homo sapiens 49-53 16207894-0 2006 Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycopeptides 54-67 mucin 1, cell surface associated Homo sapiens 96-100 16207894-3 2006 In this study, we have developed chemoenzymatic synthesis of extended MUC1 TR glycopeptides with cancer-associated O-glycosylation using a panel of recombinant human glycosyltransferases. Glycopeptides 78-91 mucin 1, cell surface associated Homo sapiens 70-74 16207894-5 2006 Glycopeptides with complete O-glycan occupancy (five sites per repeat) elicited the strongest antibody response reacting with MUC1 expressed in breast cancer cell lines in both Balb/c and MUC1.Tg mice. Glycopeptides 0-13 mucin 1, transmembrane Mus musculus 126-130 16207894-5 2006 Glycopeptides with complete O-glycan occupancy (five sites per repeat) elicited the strongest antibody response reacting with MUC1 expressed in breast cancer cell lines in both Balb/c and MUC1.Tg mice. Glycopeptides 0-13 mucin 1, transmembrane Mus musculus 188-192 16204891-1 2005 The NNA7 Fab antibody fragment recognizes the human N-type blood-group antigen comprised of the N-terminal glycopeptide of glycophorin A (GPA). Glycopeptides 107-119 FA complementation group B Homo sapiens 9-12 16177266-3 2006 In this study, we prepared a series of mucin-type glycopeptides using human glycosyltransferases, that is, ST6GalNAc1, Core1Gal-T1 and -T2, beta3Gn-T6, and Core2GnT1, and investigated their binding to immobilized Jacalin by frontal affinity chromatography (FAC). Glycopeptides 50-63 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Homo sapiens 107-117 17091533-0 2006 Direct structural assignment of neutral and sialylated N-glycans of glycopeptides using collision-induced dissociation MSn spectral matching. Glycopeptides 68-81 moesin Gallus gallus 119-122 16456804-0 2006 Complementary structural information of positive- and negative-ion MSn spectra of glycopeptides with neutral and sialylated N-glycans. Glycopeptides 82-95 moesin Gallus gallus 67-70 16456804-1 2006 Positive- and negative-ion MSn spectra of chicken egg yolk glycopeptides binding a neutral and a sialylated N-glycan were acquired by using electrospray ionization linear ion trap time-of-flight mass spectrometry (ESI-LIT-TOFMS) and collision-induced dissociation (CID) with helium as collision gas. Glycopeptides 59-72 moesin Gallus gallus 27-30 16204891-1 2005 The NNA7 Fab antibody fragment recognizes the human N-type blood-group antigen comprised of the N-terminal glycopeptide of glycophorin A (GPA). Glycopeptides 107-119 glycophorin A (MNS blood group) Homo sapiens 123-136 15656939-4 2005 Genetic studies in yeast, and biochemical data from higher eukaryotes, indicate that glycopeptides utilise the Sec61 translocon. Glycopeptides 85-98 translocon subunit SEC61 Saccharomyces cerevisiae S288C 111-116 16042579-3 2005 These natural responses to tumour-associated MUC1 glycoforms indicate that antibody reactivities are more directed to glycopeptide than to non-glycosylated peptide epitopes. Glycopeptides 118-130 mucin 1, cell surface associated Homo sapiens 45-49 15814824-6 2005 We also examined the conformational changes of MUC1 glycopeptides induced by the concerted DT to ES replacements and revealed a higher conformational flexibility of ES/P peptides compared to DT/P peptides. Glycopeptides 52-65 mucin 1, cell surface associated Homo sapiens 47-51 16104759-0 2005 Combinatorial synthesis of MUC1 glycopeptides: polymer blotting facilitates chemical and enzymatic synthesis of highly complicated mucin glycopeptides. Glycopeptides 32-45 mucin 1, cell surface associated Homo sapiens 27-31 16104759-0 2005 Combinatorial synthesis of MUC1 glycopeptides: polymer blotting facilitates chemical and enzymatic synthesis of highly complicated mucin glycopeptides. Glycopeptides 32-45 LOC100508689 Homo sapiens 131-136 16104759-0 2005 Combinatorial synthesis of MUC1 glycopeptides: polymer blotting facilitates chemical and enzymatic synthesis of highly complicated mucin glycopeptides. Glycopeptides 137-150 mucin 1, cell surface associated Homo sapiens 27-31 16104759-0 2005 Combinatorial synthesis of MUC1 glycopeptides: polymer blotting facilitates chemical and enzymatic synthesis of highly complicated mucin glycopeptides. Glycopeptides 137-150 LOC100508689 Homo sapiens 131-136 16104759-5 2005 We report here a high-throughput synthetic system for the various types of MUC1 glycopeptides exhibiting a variety of sugar moieties. Glycopeptides 80-93 mucin 1, cell surface associated Homo sapiens 75-79 16116288-2 2005 The building blocks were utilized in the solid-phase synthesis of a glycopeptide carrying two O-glycans with the consensus sequence of the tandem-repeat domain of MUC5AC. Glycopeptides 68-80 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 163-169 15826181-0 2005 Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers. Glycopeptides 0-13 proopiomelanocortin Homo sapiens 25-39 15640183-8 2005 In conclusion, our observations suggest that the molecular unit of persistence of glycopeptide resistance is a common mobile plasmid-mediated vanA-containing element within a polyclonal GREF population that changes over time. Glycopeptides 82-94 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 142-146 16400877-10 2005 All the MRSA isolates were multidrug resistant but sensitive to glycopeptides. Glycopeptides 64-77 solute carrier family 9 member A6 Homo sapiens 8-12 15519221-1 2004 Previously, we have characterized the HIV-I(SF2) gp120 glycopeptides using matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS) and nanospray electrospray ionization (ESI). Glycopeptides 55-68 serine and arginine rich splicing factor 1 Homo sapiens 44-47 15519221-1 2004 Previously, we have characterized the HIV-I(SF2) gp120 glycopeptides using matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS) and nanospray electrospray ionization (ESI). Glycopeptides 55-68 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 49-54 15491501-17 2004 G-CSF treatment is very expensive, likewise glycopeptides. Glycopeptides 44-57 colony stimulating factor 3 (granulocyte) Mus musculus 0-5 15292166-7 2004 Extensive Pronase E digestion of unlabeled Muclin was used to produce glycopeptides, which competed for binding of [35S]sulfate-labeled Muclin to zymogens. Glycopeptides 70-83 deleted in malignant brain tumors 1 Homo sapiens 43-49 15466199-4 2004 The recombinant ST6GalNAc-I and ST6GalNAc-II showed similar substrate specificity toward glycoproteins and GalNAcalpha-O-Ser/Thr glycopeptides, such as glycopeptides derived from the MUC2 mucin and the HIVgp120. Glycopeptides 129-142 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Homo sapiens 16-27 15466199-4 2004 The recombinant ST6GalNAc-I and ST6GalNAc-II showed similar substrate specificity toward glycoproteins and GalNAcalpha-O-Ser/Thr glycopeptides, such as glycopeptides derived from the MUC2 mucin and the HIVgp120. Glycopeptides 129-142 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Homo sapiens 32-44 15292166-7 2004 Extensive Pronase E digestion of unlabeled Muclin was used to produce glycopeptides, which competed for binding of [35S]sulfate-labeled Muclin to zymogens. Glycopeptides 70-83 deleted in malignant brain tumors 1 Homo sapiens 136-142 15320440-1 2004 DISTURBING EPIDEMIOLOGICAL DATA: Over the past decade there has been a continuous progression in the percentage of Staphylococcus aureus strains resistant to methicillin (MRSA), a slight progression in coagulase-negative staphylococci strains resistant to methicillin and a spectacular progression of enterococci resistant to glycopeptides, not only in hospitals but also in intensive care settings. Glycopeptides 326-339 solute carrier family 9 member A6 Homo sapiens 171-175 15283567-5 2004 MALDI/PSD analysis of glycopeptides converted to their acetyl phosphonium derivatives is an effective alternative to electron capture dissociation, as illustrated by the positioning of up to three GalNac residues along the full tandem repeat peptide sequence derived from the MUC 5AC mucin. Glycopeptides 22-35 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 276-283 15182249-5 2004 Internalized Db- and Kb-binding glycopeptides, detected with high specificity using an anti-galabiose (Gal2) monoclonal antibody, were found to appear on the cell surface of BFA-treated cells after intracellular MHC-I-binding. Glycopeptides 32-45 galectin 2 Homo sapiens 103-107 15045167-9 2004 Comparison with US ICARE (Intensive Care Antimicrobial Resistance Epidemiology)/AUR (Antimicrobial Use and Resistance) data revealed a higher AD for glycopeptides and 3rd generation cephalosporins in ICARE/AUR ICUs, but a higher AD for carbapenems in German SARI ICUs regardless of the type of ICU. Glycopeptides 149-162 basic leucine zipper ATF-like transcription factor 2 Homo sapiens 258-262 14993254-3 2004 Here we demonstrate that by using glycopeptides with high affinity for the major histocompatibility complex and glycosylated in a position corresponding to a critical T cell receptor (TcR) contact, it is possible to induce anti-TACA CTL in vivo. Glycopeptides 34-47 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 167-182 14993254-3 2004 Here we demonstrate that by using glycopeptides with high affinity for the major histocompatibility complex and glycosylated in a position corresponding to a critical T cell receptor (TcR) contact, it is possible to induce anti-TACA CTL in vivo. Glycopeptides 34-47 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 184-187 14993254-4 2004 In the current study we show that designer glycopeptides containing the Thomsen-Freidenreich (TF) antigen (beta-Gal-[1-->3]-alpha-GalNAc-O-serine) are immunogenic in vivo and generate TF-specific CTL capable of recognizing a variety of tumor cells in vitro including a MUC1-expressing tumor. Glycopeptides 43-56 mucin 1, cell surface associated Homo sapiens 272-276 12925576-0 2003 Conformational studies on the MUC1 tandem repeat glycopeptides: implication for the enzymatic O-glycosylation of the mucin protein core. Glycopeptides 49-62 mucin 1, cell surface associated Homo sapiens 30-34 14733546-0 2004 Chemical synthesis of normal and transformed PSA glycopeptides. Glycopeptides 49-62 kallikrein related peptidase 3 Homo sapiens 45-48 14991920-4 2004 For the construction of immunostimulating antigens, glycopeptide partial structures from the mucins MUC1 and MUC4 carrying the tumor-associated sialyl-T(N), alpha2,6-sialyl-T and alpha2,3-sialyl-T antigens have been synthesized. Glycopeptides 52-64 mucin 1, cell surface associated Homo sapiens 100-104 14991920-4 2004 For the construction of immunostimulating antigens, glycopeptide partial structures from the mucins MUC1 and MUC4 carrying the tumor-associated sialyl-T(N), alpha2,6-sialyl-T and alpha2,3-sialyl-T antigens have been synthesized. Glycopeptides 52-64 mucin 4, cell surface associated Homo sapiens 109-113 14679514-3 2003 The advantages of the PTMSEL linker are demonstrated in the synthesis of glycopeptides from the liver intestine (LI)-cadherin and the mucin MUC1, bearing carbohydrate moieties such as N-linked chitobiose or O-linked sialyl-T(N)-residues. Glycopeptides 73-86 cadherin 17 Homo sapiens 96-125 14558142-7 2003 Moreover, the interaction between IMP2 and GAL6/BLH1, a recently isolated gene involved in the regulation of GAL genes that shares with Imp2 the ability to protect cells from the glycopeptide bleomycin, was also analysed. Glycopeptides 179-191 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 34-38 14604374-0 2003 Chemical synthesis of CD52 glycopeptides containing the acid-labile fucosyl linkage. Glycopeptides 27-40 CD52 molecule Homo sapiens 22-26 14517945-2 2003 Mutations in the sialidase gene NEU1, located on chromosome 6p21.3, result in autosomal recessive disorder, sialidosis, which is characterized by the progressive lysosomal storage of sialylated glycopeptides and oligosaccharides. Glycopeptides 194-207 neuraminidase 1 Homo sapiens 32-36 14552419-1 2003 Based on structural information reported for the tumour-associated epithelial mucin MUC1, glycopeptides have been synthesized which contain tumour-associated saccharide antigens. Glycopeptides 90-103 mucin 1, cell surface associated Homo sapiens 84-88 12847092-6 2003 Like P-selectin, A. phagocytophilum bound to purified human PSGL-1 and to glycopeptides modeled after the N terminus of human PSGL-1 that presented sLex on an O-glycan. Glycopeptides 74-87 selectin P ligand Homo sapiens 126-132 12945896-1 2003 Glycopeptides that bind to MHC molecules on antigen presenting cells may elicit carbohydrate selective T cells. Glycopeptides 0-13 major histocompatibility complex, class I, C Homo sapiens 27-30 12929179-5 2003 The phosphate group on site Ser12 of tryptic peptide 8-22 of most phosphorylated alpha(s1)-CN (11 phosphate groups) was localized and the oligosaccharide sequence of the main tryptic glycopeptides of two kappa-CN components was determined by means of MS/MS analysis. Glycopeptides 183-196 proteasome 26S subunit, non-ATPase 1 Homo sapiens 81-93 12945896-6 2003 Our observation suggests an explanation for previous findings, which show that glycopeptides isolated from MHC molecules in nature usually carry small saccharides. Glycopeptides 79-92 major histocompatibility complex, class I, C Homo sapiens 107-110 12778480-1 2003 Multi-component glycopeptide libraries and single glycopeptides were used for immunization of mice with the aim of inducing strong T helper cell responses to the repetitive sequence of MUC1 expressed by human tumor cells. Glycopeptides 50-63 mucin 1, transmembrane Mus musculus 185-189 12778480-2 2003 The glycopeptides and glycopeptide libraries were modeled upon the native human MUC1 amino acid variable number of tandem repeats sequence by introduction of modifications in the MHC anchor positions to optimally fulfil the binding requirements of the A(d) MHC class II molecule in the BALB/c mouse. Glycopeptides 4-17 mucin 1, cell surface associated Homo sapiens 80-84 12778480-3 2003 The immunogenicity of the MUC1 glycopeptides in BALB/c mice was determined by immunization in complete Freund"s adjuvant and assaying lymph node T cells for a proliferative response to the glycopeptide used. Glycopeptides 31-44 mucin 1, transmembrane Mus musculus 26-30 12778480-3 2003 The immunogenicity of the MUC1 glycopeptides in BALB/c mice was determined by immunization in complete Freund"s adjuvant and assaying lymph node T cells for a proliferative response to the glycopeptide used. Glycopeptides 31-43 mucin 1, transmembrane Mus musculus 26-30 14633362-6 2003 A 17-kb composite cluster was identified in a single hospital isolate linking determinants for glycopeptide (vanA), macrolide-lincosamide-streptogramin B [erm(B)], and aminoglycoside-streptothricin (aadE-sat4-aphA-3) resistances. Glycopeptides 95-107 aminoglycoside phosphotransferase Enterococcus faecium 209-215 12770769-4 2003 Protection against the action of PLG, PLP and sulfhydryl modifying reagents was offered by GDP-fucose, GDP, and the acceptor substrate, a transferrin-derived biantennary glycopeptide with terminal GlcNAc residues. Glycopeptides 170-182 pyridoxal phosphatase Homo sapiens 38-41 12527303-6 2003 The IgG-Fc is a homodimer of N-linked glycopeptide chains comprised of two immunoglobulin domains (Cgamma2, Cgamma3) that dimerise via inter-heavy chain disulphide bridges at the N-terminal region and non-covalent interactions between the C-terminal Cgamma3 domains. Glycopeptides 38-50 immunoglobulin heavy constant gamma 3 (G3m marker) Homo sapiens 108-115 12523830-0 2003 Glycopeptides as oligosaccharide mimics: high affinity sialopeptide ligands for sialoadhesin from combinatorial libraries. Glycopeptides 0-13 sialic acid binding Ig like lectin 1 Homo sapiens 80-92 12770766-6 2003 During the synthesis three intermediate glycopeptides containing O-linked GalNAc, Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, and Neu5Ac(alpha2-3)Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, respectively, were isolated in mg quantities. Glycopeptides 40-53 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 86-93 12770766-6 2003 During the synthesis three intermediate glycopeptides containing O-linked GalNAc, Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, and Neu5Ac(alpha2-3)Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, respectively, were isolated in mg quantities. Glycopeptides 40-53 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 101-108 12770766-6 2003 During the synthesis three intermediate glycopeptides containing O-linked GalNAc, Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, and Neu5Ac(alpha2-3)Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, respectively, were isolated in mg quantities. Glycopeptides 40-53 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 114-121 12770766-6 2003 During the synthesis three intermediate glycopeptides containing O-linked GalNAc, Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, and Neu5Ac(alpha2-3)Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, respectively, were isolated in mg quantities. Glycopeptides 40-53 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 170-177 12770766-6 2003 During the synthesis three intermediate glycopeptides containing O-linked GalNAc, Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, and Neu5Ac(alpha2-3)Gal(beta1-4)GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc, respectively, were isolated in mg quantities. Glycopeptides 40-53 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 183-190 12565922-0 2003 Chemoenzymatic synthesis of high-mannose type HIV-1 gp120 glycopeptides. Glycopeptides 58-71 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 52-57 12565922-2 2003 Thus, the high-mannose type glycopeptides [gp120 (336-342)] containing Man(9), Man(6) and Man(5) moieties, respectively, were synthesized in satisfactory yields via transglycosylation to the acetylglucosaminyl peptide, using the recombinant Arthrobacter Endo-beta-N-acetyl-glucosaminidase (Endo-A) as the key enzyme. Glycopeptides 28-41 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 43-48 12565922-2 2003 Thus, the high-mannose type glycopeptides [gp120 (336-342)] containing Man(9), Man(6) and Man(5) moieties, respectively, were synthesized in satisfactory yields via transglycosylation to the acetylglucosaminyl peptide, using the recombinant Arthrobacter Endo-beta-N-acetyl-glucosaminidase (Endo-A) as the key enzyme. Glycopeptides 28-41 endo-beta-N-acetylglucosaminidase Homo sapiens 254-288 12565922-2 2003 Thus, the high-mannose type glycopeptides [gp120 (336-342)] containing Man(9), Man(6) and Man(5) moieties, respectively, were synthesized in satisfactory yields via transglycosylation to the acetylglucosaminyl peptide, using the recombinant Arthrobacter Endo-beta-N-acetyl-glucosaminidase (Endo-A) as the key enzyme. Glycopeptides 28-41 endo-beta-N-acetylglucosaminidase Homo sapiens 290-296 12461079-5 2002 We show that DCs endocytose MUC1 glycopeptides, transport them to acidic compartments, process them into smaller peptides, and present them on major histocompatability complex (MHC) class II molecules without removing the carbohydrates. Glycopeptides 33-46 mucin 1, cell surface associated Homo sapiens 28-32 11697954-7 2001 The outlined chemoenzymatic approach was applied to glycopeptides from the tandem repeat domain of the mucin MUC1, as well as to neoglycosylated derivatives of a T cell stimulating viral peptide. Glycopeptides 52-65 mucin 1, cell surface associated Homo sapiens 109-113 12473113-6 2002 All pp-GalNAc-T isozymes tested exhibited distinct specificities toward glycopeptides. Glycopeptides 72-85 beta-1,4-N-acetyl-galactosaminyltransferase 1 Homo sapiens 7-15 11867604-11 2002 LC-ESMS analysis of tryptic peptides indicated that PEDF A and B exhibit differences in glycopeptides containing N-acetylneuraminic acid (NeuAc) and N-acetylhexosamine (HexNAc). Glycopeptides 88-101 serpin family F member 1 Homo sapiens 52-56 12175243-0 2002 Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains. Glycopeptides 66-79 LOC100508689 Homo sapiens 14-19 11907045-4 2002 We now report that monoclonal antibodies-induced L-selectin dimerization enhances L-selectin leukocyte tethering to purified physiological L-selectin ligands and glycopeptides. Glycopeptides 162-175 selectin L Homo sapiens 49-59 11907045-4 2002 We now report that monoclonal antibodies-induced L-selectin dimerization enhances L-selectin leukocyte tethering to purified physiological L-selectin ligands and glycopeptides. Glycopeptides 162-175 selectin L Homo sapiens 82-92 11907045-4 2002 We now report that monoclonal antibodies-induced L-selectin dimerization enhances L-selectin leukocyte tethering to purified physiological L-selectin ligands and glycopeptides. Glycopeptides 162-175 selectin L Homo sapiens 82-92 11939716-5 2002 The radioscanning of the samples prepared from the culture medium and the apical epithelial membranes subjected to SDS-PAGE and western blotting disclosed that the released, water soluble 97kDa MBP glycopeptide was labeled with proline and palmitate. Glycopeptides 198-210 myelin basic protein Rattus norvegicus 194-197 29712138-2 2001 It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential. Glycopeptides 83-95 golgi glycoprotein 1 Homo sapiens 151-170 11710528-2 2001 The radiolabeled hTR glycopeptides were prepared and fractionated by a lectin chromatography of Concanavalin A-Sepharose. Glycopeptides 21-34 telomerase RNA component Homo sapiens 17-20 11710528-3 2001 The composition analysis of hTR glycopeptides revealed that Con A-I contains both mannose and fucose, whereas Con A-III has mannose exclusively. Glycopeptides 32-45 telomerase RNA component Homo sapiens 28-31 29712138-2 2001 It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential. Glycopeptides 83-95 golgi glycoprotein 1 Homo sapiens 172-177 29712138-2 2001 It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential. Glycopeptides 83-95 selectin E Homo sapiens 151-161 12240213-1 2001 The protease-catalyzed synthesis of amino acid est-carbohydrate conjugates as glycopeptide analogues has been achieved in a highly regioselective and carbohydrate-specific manner using amino acid vinyl ester acyl donors and minimally or completely unprotected carbohydrate acyl acceptors, which together probed active sites of proteases to reveal yield efficiencies that are modulated by the carbohydrate C-2 substitutent, and that may be exploited to allow selective one-pot syntheses. Glycopeptides 78-90 complement C2 Homo sapiens 405-408 11278534-7 2001 However, when incubated with MUC5AC and EA2 glycopeptides (obtained by the prior action of ppGaNTase-T1), additional incorporation of GalNAc was achieved, resulting in new hydroxyamino acid modification. Glycopeptides 44-57 calcium voltage-gated channel subunit alpha1 A Homo sapiens 40-43 11675980-8 2001 However, there is also reason for concern about the recent emergence of MRSA resistant to glycopeptides, such as vancomycin. Glycopeptides 90-103 solute carrier family 9 member A6 Homo sapiens 72-76 11555617-0 2001 Evidence for glycosylation-dependent activities of polypeptide N-acetylgalactosaminyltransferases rGalNAc-T2 and -T4 on mucin glycopeptides. Glycopeptides 126-139 chondroitin sulfate N-acetylgalactosaminyltransferase 2 Rattus norvegicus 98-108 11555617-0 2001 Evidence for glycosylation-dependent activities of polypeptide N-acetylgalactosaminyltransferases rGalNAc-T2 and -T4 on mucin glycopeptides. Glycopeptides 126-139 LOC100508689 Homo sapiens 120-125 11384997-7 2001 The CRDs of DC-SIGN and DC-SIGNR bind Man(9)GlcNAc(2) oligosaccharide 130- and 17-fold more tightly than mannose, and affinity for a glycopeptide bearing two such oligosaccharides is increased by a further factor of 5- to 25-fold. Glycopeptides 133-145 C-type lectin domain family 4 member M Homo sapiens 24-32 11445553-2 2001 In vitro metabolic labeling of cells with either [(3)H] glucosamine or [(3)H] threonine, together with tomato lectin staining, revealed that nerve growth factor (NGF) stimulation caused a decrease in the poly-N-acetyllactosamine synthesis of high-molecular-weight glycopeptides from PC12 cells. Glycopeptides 264-277 nerve growth factor Rattus norvegicus 162-165 11240145-0 2001 Structure determination and by-product profile of the NK(2) receptor antagonist nepadutant, a bicyclic glycopeptide. Glycopeptides 103-115 tachykinin receptor 2 Homo sapiens 54-68 11263562-1 2001 Selective glycopeptide mapping of recombinant human erythropoietin (rhEPO) used as a model glycoprotein was successfully carried out by on-line high-performance liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) using a Vydac C18 column eluted in acetonitrile-1 mM ammonium acetate, pH 6.8. rhEPO expressed in a Chinese hamster ovary clone was exhaustively digested into four glycopeptides and nine peptides with endoproteinase Glu-C. Glycopeptides 401-414 erythropoietin Homo sapiens 52-66 16557681-0 2001 Two Structurally Distinct VanA Resistance Elements at Different Locations in a Glycopeptide-Resistant Strain of Enterococcus faecalis. Glycopeptides 79-91 VanA Enterococcus faecalis 26-30 11231363-4 2001 The variety of O-glycan glycoform was determined by estimating the precise molecular weights of the IgA1 hinge glycopeptides using matrix-assisted laser desorption ionization time of flight mass spectrometry. Glycopeptides 111-124 immunoglobulin heavy constant alpha 1 Homo sapiens 100-104 11231363-5 2001 RESULTS: The peak distribution of IgA1 hinge glycopeptides clearly shifted to lesser molecular weights in both glomerular and serum IgA1 in IgAN compared with the serum IgA1 of controls. Glycopeptides 45-58 immunoglobulin heavy constant alpha 1 Homo sapiens 34-38 11231363-5 2001 RESULTS: The peak distribution of IgA1 hinge glycopeptides clearly shifted to lesser molecular weights in both glomerular and serum IgA1 in IgAN compared with the serum IgA1 of controls. Glycopeptides 45-58 immunoglobulin heavy constant alpha 1 Homo sapiens 132-136 11231363-5 2001 RESULTS: The peak distribution of IgA1 hinge glycopeptides clearly shifted to lesser molecular weights in both glomerular and serum IgA1 in IgAN compared with the serum IgA1 of controls. Glycopeptides 45-58 IGAN1 Homo sapiens 140-144 11231363-5 2001 RESULTS: The peak distribution of IgA1 hinge glycopeptides clearly shifted to lesser molecular weights in both glomerular and serum IgA1 in IgAN compared with the serum IgA1 of controls. Glycopeptides 45-58 immunoglobulin heavy constant alpha 1 Homo sapiens 132-136 11231363-8 2001 These results indicate that the decreased sialylation and galactosylation of the IgA1 hinge glycopeptides play a crucial role in its glomerular deposition in IgAN. Glycopeptides 92-105 immunoglobulin heavy constant alpha 1 Homo sapiens 81-85 11231363-8 2001 These results indicate that the decreased sialylation and galactosylation of the IgA1 hinge glycopeptides play a crucial role in its glomerular deposition in IgAN. Glycopeptides 92-105 IGAN1 Homo sapiens 158-162 11290314-8 2001 Although the frequency of enterococcal infections is very low in most Latin America countries, the finding of glycopeptide (VanA) resistance in E. faecalis increases concern about apreading antimicrobial resistance in this region. Glycopeptides 110-122 VanA Enterococcus faecalis 124-128 11141302-7 2001 An analytical method for the microheterogeneity of the IgA1 hinge glycopeptide (HGP33) was developed to determine the difference between these IgA1 fractions by capillary electrophoresis (CE). Glycopeptides 66-78 immunoglobulin heavy constant alpha 1 Homo sapiens 55-59 11221889-6 2001 When the MUC2 tandem repeat peptide was glycosylated with a mixture of the normal mucosa extract and recombinant N-acetylgalactosaminyltransferase-3, larger amounts of glycopeptides with higher contents of GalNAc residues were produced. Glycopeptides 168-181 mucin 2, oligomeric mucus/gel-forming Homo sapiens 9-13 11221889-6 2001 When the MUC2 tandem repeat peptide was glycosylated with a mixture of the normal mucosa extract and recombinant N-acetylgalactosaminyltransferase-3, larger amounts of glycopeptides with higher contents of GalNAc residues were produced. Glycopeptides 168-181 chondroitin sulfate synthase 3 Homo sapiens 113-148 11141302-7 2001 An analytical method for the microheterogeneity of the IgA1 hinge glycopeptide (HGP33) was developed to determine the difference between these IgA1 fractions by capillary electrophoresis (CE). Glycopeptides 66-78 immunoglobulin heavy constant alpha 1 Homo sapiens 143-147 11399322-1 2000 Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry was applied to studies of the molecular heterogeneity of desialylated human IgA1 hinge region glycopeptides released with two IgA1 proteases. Glycopeptides 183-196 immunoglobulin heavy constant alpha 1 Homo sapiens 165-169 11114588-5 2001 Three glycopeptides, having one Asn residue to which the carbohydrate chain is linked, are obtained by lysylendopeptidase digestion of the heat-solubilized zonae containing intact ZPB, and lysylendopeptidase and chymotryptic digestions of endo-beta-galactosidase-digested ZPB. Glycopeptides 6-19 zona pellucida glycoprotein 4 Sus scrofa 180-183 11114588-5 2001 Three glycopeptides, having one Asn residue to which the carbohydrate chain is linked, are obtained by lysylendopeptidase digestion of the heat-solubilized zonae containing intact ZPB, and lysylendopeptidase and chymotryptic digestions of endo-beta-galactosidase-digested ZPB. Glycopeptides 6-19 zona pellucida glycoprotein 4 Sus scrofa 272-275 11399322-1 2000 Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry was applied to studies of the molecular heterogeneity of desialylated human IgA1 hinge region glycopeptides released with two IgA1 proteases. Glycopeptides 183-196 immunoglobulin heavy constant alpha 1 Homo sapiens 215-219 11249650-4 2000 In this review, we will discuss such crystal structures, as well as structures of glycopeptides and alternative T-cell antigens presented by MHC molecules. Glycopeptides 82-95 major histocompatibility complex, class I, C Homo sapiens 141-144 10952577-7 2000 The vanB2 resistance element appears to be widespread among VanB glycopeptide-resistant E. faecium strains isolated in Scottish hospitals. Glycopeptides 65-77 D-alanine--D-lactate ligase Enterococcus faecalis 4-9 10952577-7 2000 The vanB2 resistance element appears to be widespread among VanB glycopeptide-resistant E. faecium strains isolated in Scottish hospitals. Glycopeptides 65-77 D-alanine--D-lactate ligase Enterococcus faecium 60-64 10963678-8 2000 Overall, the data are consistent with a mode of lipoglycan recognition similar to that proposed for glycopeptides, in which the TCR alpha and beta chains survey a surface composed of both mCD1.1 and the carbohydrate portion of alpha-GalCer. Glycopeptides 100-113 T cell receptor alpha chain Mus musculus 128-137 10963678-8 2000 Overall, the data are consistent with a mode of lipoglycan recognition similar to that proposed for glycopeptides, in which the TCR alpha and beta chains survey a surface composed of both mCD1.1 and the carbohydrate portion of alpha-GalCer. Glycopeptides 100-113 CD1d1 antigen Mus musculus 188-194 11019912-8 2000 Together, these data provide further evidence for the natural presentation by human class I MHC of glycopeptides carrying terminal O-GlcNAc residues in vivo. Glycopeptides 99-112 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 131-139 10882013-3 2000 To further characterize this system, the synthesis of glycopeptides from PSGL-1 was undertaken. Glycopeptides 54-67 selectin P ligand Homo sapiens 73-79 10660465-1 2000 We have developed an assay system for endo-beta-N-acetylglucosaminidase and glycoamidase (PNGase), using Eu(3+)-labeled Man(9)GlcNAc(2) glycopeptides as substrates in combination with lectin capture. Glycopeptides 136-149 O-GlcNAcase Homo sapiens 43-71 11085411-7 2000 The analysis of phospholipase A2 from the venom of individual bees indicated that the variation and relative abundances of different glycopeptides were similar between the younger and the older bees. Glycopeptides 133-146 phospholipase A2 Apis mellifera 16-32 10784033-5 2000 As demonstrated by both ELISA and FACS analysis, the glycopeptides induced high titers of anti-Tn antibodies in mice, in the absence of a carrier molecule. Glycopeptides 53-66 acyl-CoA synthetase long-chain family member 1 Mus musculus 34-38 10425209-14 1999 The binding was non-covalent and not strong because the asialo-, agalacto-hinge glycopeptide was eluted slightly slower than the native one from the column and the bound IgA1 was dissociated in the presence of 1 M NaCl. Glycopeptides 80-92 immunoglobulin heavy constant alpha 1 Homo sapiens 170-174 10588068-5 1999 The glycopeptides [beta-D-Glc-(1-->6)-alpha-D-Man-(1-->6)-D-Man]-O-Ser2-Pro2 (No. Glycopeptides 4-17 jagged canonical Notch ligand 2 Homo sapiens 73-77 10532235-0 1999 NMR analysis of human salivary mucin (MUC7) derived O-linked model glycopeptides: comparison of structural features and carbohydrate-peptide interactions. Glycopeptides 67-80 LOC100508689 Homo sapiens 31-36 10532235-0 1999 NMR analysis of human salivary mucin (MUC7) derived O-linked model glycopeptides: comparison of structural features and carbohydrate-peptide interactions. Glycopeptides 67-80 mucin 7, secreted Homo sapiens 38-42 10094775-6 1999 Examples are shown with mannosyl- and mucin-type glycopeptides. Glycopeptides 49-62 LOC100508689 Homo sapiens 38-43 10341169-3 1999 Accumulating evidence now indicates that the use of the glycopeptide avoparcin as a growth promoter has created in food animals a major reservoir of Enterococcus faecium, which contains the high level glycopeptide resistance determinant vanA, located on the Tn1546 transposon. Glycopeptides 56-68 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 237-241 10200322-2 1999 Bleomycin (BLM), a clinically used glycopeptide anticancer agent, is deaminated in vitro by Blmh. Glycopeptides 35-47 bleomycin hydrolase Mus musculus 92-96 10417422-0 1999 Crystallization and preliminary X-ray characterization of VanA from Enterococcus faecium BM4147: towards the molecular basis of bacterial resistance to the glycopeptide antibiotic vancomycin. Glycopeptides 156-168 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 58-62 10348770-6 1999 Furthermore, the msbB mutant was resistant to glycopeptides (vancomycin, teicoplanin), whereas the rfa, lpxA, and lpxD mutants were susceptible. Glycopeptides 46-59 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase Escherichia coli 17-21 10226365-0 1999 Characterization of O-glycosylation sites in MUC2 glycopeptides by nanoelectrospray QTOF mass spectrometry. Glycopeptides 50-63 mucin 2, oligomeric mucus/gel-forming Homo sapiens 45-49 10230695-5 1999 In addition, two methods were developed to detect the different genotypes of glycopeptide resistance described in enterococci: a multiplex PCR assay for detection of vanA, vanB, vanC-1, vanC-2/3 ligase genes including 16S rRNA gene control primers and a sandwich hybridization assay to confirm vanA and vanB PCR-positive strains. Glycopeptides 77-89 D-alanine--D-lactate ligase Enterococcus faecium 172-176 10230695-5 1999 In addition, two methods were developed to detect the different genotypes of glycopeptide resistance described in enterococci: a multiplex PCR assay for detection of vanA, vanB, vanC-1, vanC-2/3 ligase genes including 16S rRNA gene control primers and a sandwich hybridization assay to confirm vanA and vanB PCR-positive strains. Glycopeptides 77-89 D-alanine--D-lactate ligase Enterococcus faecium 303-307 10230695-7 1999 Four strains were found with acquired resistance to glycopeptides: one E. faecium and one E. gallinarum were vanA positive, and two E. faecium isolates were vanB positive. Glycopeptides 52-65 D-alanine--D-lactate ligase Enterococcus faecium 157-161 10021921-1 1999 Glycopeptides of hMOG(30-50) containing a glucosyl moiety on the side-chains of Asn, Ser or Hyp at position 31 were synthesised. Glycopeptides 0-13 myelin oligodendrocyte glycoprotein Homo sapiens 17-21 10021921-1 1999 Glycopeptides of hMOG(30-50) containing a glucosyl moiety on the side-chains of Asn, Ser or Hyp at position 31 were synthesised. Glycopeptides 0-13 phosphate regulating endopeptidase homolog X-linked Homo sapiens 92-95 10021921-3 1999 Anti-hMOG(30-50) antibodies were detected only using the glycopeptide [Asn31(N-Glc)]hMOG(30-50). Glycopeptides 57-69 myelin oligodendrocyte glycoprotein Homo sapiens 5-9 10021921-3 1999 Anti-hMOG(30-50) antibodies were detected only using the glycopeptide [Asn31(N-Glc)]hMOG(30-50). Glycopeptides 57-69 myelin oligodendrocyte glycoprotein Homo sapiens 84-88 9824507-1 1998 The CAMPATH-1H (CD52) antigen is a 21 000-28 000 MW glycopeptide antigen that is highly expressed on T and B lymphocytes and is coupled to the membrane by a glycosylphosphatidylinositol (GPI) anchoring structure. Glycopeptides 52-64 CD52 molecule Homo sapiens 16-20 10217327-0 1999 Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides. Glycopeptides 120-133 mucin 1, cell surface associated Homo sapiens 39-43 10217327-0 1999 Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides. Glycopeptides 120-133 mucin 1, cell surface associated Homo sapiens 83-87 10023770-2 1999 Immunization with an H-2Kb-restricted glycopeptide RGY8-6H-Gal2 generates a population of cytotoxic T cells that express both alpha/beta TCR, specific for glycopeptide, and gamma/delta TCR, specific for the disaccharide, even on glycolipids. Glycopeptides 38-50 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 137-140 10023770-2 1999 Immunization with an H-2Kb-restricted glycopeptide RGY8-6H-Gal2 generates a population of cytotoxic T cells that express both alpha/beta TCR, specific for glycopeptide, and gamma/delta TCR, specific for the disaccharide, even on glycolipids. Glycopeptides 38-50 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 155-188 9873537-1 1998 Application of the Ugi four-component condensation to rapidly synthesize a library of glycopeptide mimics of the tetrasaccharide SLe(x) as inhibitors of E- and P-selectin, and to study the effect of varied functionality in mimics on the inhibition is described. Glycopeptides 86-98 selectin P Homo sapiens 160-170 10211705-1 1998 Glycopeptides containing the N-linked oligosaccharide from human serum IgA1 were analyzed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS). Glycopeptides 0-13 immunoglobulin heavy constant alpha 1 Homo sapiens 71-75 10211705-5 1998 On the other hand, the GP2 fraction corresponded to the glycopeptides having a fully galactosylated and fucosylated bianntena sugar chain partly bearing a bisecting GlcNAc residue. Glycopeptides 56-69 glycoprotein 2 Homo sapiens 23-26 9788808-9 1998 However, these relatively new enterococcal resistances appear still to be evolving; there have now been reports of transferable VanB resistance associated with either large chromosomally borne transposons or plasmids, genetic linkage of glycopeptide resistance and genes conferring high-level resistance to aminoglycoside antibiotics, epidemic strains of glycopeptide-resistant Enterococcus faecium isolated from multiple patients in numerous hospitals, and of glycopeptide dependence (mutant enterococci that actually require these agents for growth). Glycopeptides 237-249 D-alanine--D-lactate ligase Enterococcus faecium 128-132 9788808-9 1998 However, these relatively new enterococcal resistances appear still to be evolving; there have now been reports of transferable VanB resistance associated with either large chromosomally borne transposons or plasmids, genetic linkage of glycopeptide resistance and genes conferring high-level resistance to aminoglycoside antibiotics, epidemic strains of glycopeptide-resistant Enterococcus faecium isolated from multiple patients in numerous hospitals, and of glycopeptide dependence (mutant enterococci that actually require these agents for growth). Glycopeptides 355-367 D-alanine--D-lactate ligase Enterococcus faecium 128-132 9705282-6 1998 Upon incubation of a glycosylatable peptide R-Asn-X-Thr-R" with permeabilized yeast spheroplasts, we detected formation of both glycosylated peptide and the peptide product expected from PNGase-mediated deglycosylation of this glycopeptide, namely, R-Asp-X-Thr-R". Glycopeptides 227-239 N-glycanase 1 Homo sapiens 187-193 9801825-2 1998 The solution conformation of these MUC1-related synthetic glycopeptides and the control, non-glycosylated decapeptide AcPAPGSTAPPA have been investigated using NMR spectroscopy. Glycopeptides 58-71 mucin 1, cell surface associated Homo sapiens 35-39 9574545-1 1998 The M and N human blood group glycopeptide Ags are carried on RBCs by glycophorin A. Glycopeptides 30-42 glycophorin A (MNS blood group) Homo sapiens 70-83 9870359-0 1998 Different O-glycosylation of respiratory mucin glycopeptides from a patient with cystic fibrosis. Glycopeptides 47-60 LOC100508689 Homo sapiens 41-46 9870359-1 1998 The O-linked oligosaccharides from three fractions of highly glycosylated mucin glycopeptides obtained from sputum of a patient with cystic fibrosis were characterized and compared regarding size, composition, sequence and when possible linkage positions. Glycopeptides 80-93 LOC100508689 Homo sapiens 74-79 9705247-3 1998 We have previously demonstrated that tanapox virus (TPV) infected cells secrete an early 38 kDa glycopeptide that binds to human (h) interferon-gamma, hIL-2, and hIL-5. Glycopeptides 96-108 interferon gamma Homo sapiens 133-149 9705247-3 1998 We have previously demonstrated that tanapox virus (TPV) infected cells secrete an early 38 kDa glycopeptide that binds to human (h) interferon-gamma, hIL-2, and hIL-5. Glycopeptides 96-108 interleukin 2 Homo sapiens 151-156 9705247-3 1998 We have previously demonstrated that tanapox virus (TPV) infected cells secrete an early 38 kDa glycopeptide that binds to human (h) interferon-gamma, hIL-2, and hIL-5. Glycopeptides 96-108 interleukin 5 Homo sapiens 162-167 9705247-9 1998 Based on TNF-alpha affinity chromatography, this activity appears to be associated with a 38 kDa glycopeptide. Glycopeptides 97-109 tumor necrosis factor Homo sapiens 9-18 9881747-5 1998 CD studies of natural and synthetic diproline-rich peptides and glycopeptides indicated that polyproline type structures do play a significant role in the conformational dynamics of MUC7. Glycopeptides 64-77 mucin 7, secreted Homo sapiens 182-186 9555659-0 1998 Analyses of IgA1 hinge glycopeptides in IgA nephropathy by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Glycopeptides 23-36 immunoglobulin heavy constant alpha 1 Homo sapiens 12-16 9613824-2 1998 Glycopeptides from the ConA-bound fraction corresponding to the component PP3 were obtained by Pronase digestion and were separated by gel filtration into high and low-molecular-mass glycopeptides. Glycopeptides 183-196 glycosylation dependent cell adhesion molecule 1 Bos taurus 74-77 9555659-9 1998 These results suggested the presence of a defect in the Gal and/or GalNAc residues in the IgA1 hinge glycopeptides in IgAN. Glycopeptides 101-114 immunoglobulin heavy constant alpha 1 Homo sapiens 90-94 9555659-9 1998 These results suggested the presence of a defect in the Gal and/or GalNAc residues in the IgA1 hinge glycopeptides in IgAN. Glycopeptides 101-114 IGAN1 Homo sapiens 118-122 9455924-1 1997 We previously demonstrated that gp120/160 (Env) of HIV-1 interact in a carbohydrate-specific manner with mannosyl/N-acetylglucosaminyl derivatives and that HIV-1LAI infection of monocytic U937 and lymphoid CEM cells was inhibited by CD4-free Concanavalin A-reactive glycopeptides from U937 cells. Glycopeptides 266-279 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 32-41 9485374-1 1998 Bleomycin hydrolase (BH) is unusual among cysteine proteinases because it appears to form multihomomeric structures, inactivates the antitumor glycopeptide bleomycin, and contains a unique C-terminal amino acid sequence. Glycopeptides 143-155 bleomycin hydrolase Homo sapiens 0-19 9485374-1 1998 Bleomycin hydrolase (BH) is unusual among cysteine proteinases because it appears to form multihomomeric structures, inactivates the antitumor glycopeptide bleomycin, and contains a unique C-terminal amino acid sequence. Glycopeptides 143-155 bleomycin hydrolase Homo sapiens 21-23 9548367-5 1998 We show here that phosphorylation of L1 is reduced concomitant with reduced neurite outgrowth when the L1/NCAM interaction is inhibited by oligomannosidic glycopeptides. Glycopeptides 155-168 neural cell adhesion molecule 1 Mus musculus 106-110 9579798-6 1998 To overcome these difficulties, without resynthesis, the STn(c) glycopeptide was modified by attachment of an MMCCH (4-(4-N-maieimidomethyl) cyclohexane-1-carboxyl hydrazide) spacer arm to the aldehyde derivative, and then conjugated with thiolated KLH. Glycopeptides 64-76 eukaryotic translation elongation factor 1 alpha 2 Homo sapiens 57-60 9455924-1 1997 We previously demonstrated that gp120/160 (Env) of HIV-1 interact in a carbohydrate-specific manner with mannosyl/N-acetylglucosaminyl derivatives and that HIV-1LAI infection of monocytic U937 and lymphoid CEM cells was inhibited by CD4-free Concanavalin A-reactive glycopeptides from U937 cells. Glycopeptides 266-279 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 43-46 9455924-6 1997 Mannan also inhibited Env binding to surface glycopeptides obtained after trypsin treatment of macrophages. Glycopeptides 45-58 endogenous retrovirus group K member 20 Homo sapiens 22-25 9189858-2 1997 The competitive inhibition assays of the IgA1-IgA1 binding were performed using the following candidates for inhibitors: native IgA1 hinge glycopeptide (nHGP), IgA1, IgA2, and IgG. Glycopeptides 139-151 immunoglobulin heavy constant alpha 1 Homo sapiens 41-45 18636497-3 1997 Sialylation profiles were quantitated by reversed-phase HPLC separations of the site-specific pools of tryptic glycopeptides representing IFN-gamma"s two potential N-linked glycosylation sites (i.e., Asn(25) and Asn(97)). Glycopeptides 111-124 interferon gamma Homo sapiens 138-147 9189858-2 1997 The competitive inhibition assays of the IgA1-IgA1 binding were performed using the following candidates for inhibitors: native IgA1 hinge glycopeptide (nHGP), IgA1, IgA2, and IgG. Glycopeptides 139-151 immunoglobulin heavy constant alpha 1 Homo sapiens 46-50 9189858-2 1997 The competitive inhibition assays of the IgA1-IgA1 binding were performed using the following candidates for inhibitors: native IgA1 hinge glycopeptide (nHGP), IgA1, IgA2, and IgG. Glycopeptides 139-151 immunoglobulin heavy constant alpha 1 Homo sapiens 46-50 9189858-2 1997 The competitive inhibition assays of the IgA1-IgA1 binding were performed using the following candidates for inhibitors: native IgA1 hinge glycopeptide (nHGP), IgA1, IgA2, and IgG. Glycopeptides 139-151 immunoglobulin heavy constant alpha 1 Homo sapiens 46-50 9065790-4 1997 Our investigations indicated that a peptide:N-glycanase (PNGase) is present in ER membranes that has the capacity to release from radiolabelled glycopeptides glucosylated as well as non-glucosylated polymannose oligosaccharides terminating at their reducing end in a di-N-acetylchitobiose sequence (OS-GlcNAc2). Glycopeptides 144-157 N-glycanase 1 Rattus norvegicus 36-55 9109096-7 1997 Both glycopeptides with little or no antimicrobial activity and semisynthetic glycopeptides active against VanA resistant enterococci were inducers. Glycopeptides 78-91 VanA Enterococcus faecalis 107-111 9259029-6 1997 If the incidence of MRSA increases, drugs such as the glycopeptides will be of more importance. Glycopeptides 54-67 solute carrier family 9 member A6 Homo sapiens 20-24 9065790-4 1997 Our investigations indicated that a peptide:N-glycanase (PNGase) is present in ER membranes that has the capacity to release from radiolabelled glycopeptides glucosylated as well as non-glucosylated polymannose oligosaccharides terminating at their reducing end in a di-N-acetylchitobiose sequence (OS-GlcNAc2). Glycopeptides 144-157 N-glycanase 1 Rattus norvegicus 57-63 8756692-5 1996 Tryptic cleavage of pig AE2 in the Z-loop produced C-terminal glycopeptides and was unaffected by deglycosylation, whereas the smaller rabbit AE2 C-terminal tryptic peptide lacked oligosaccharide, consistent with the respective amino acid sequences. Glycopeptides 62-75 solute carrier family 4 member 2 Sus scrofa 24-27 9013598-3 1997 The mass spectra of the glycopeptides exhibit characteristic clusters of peaks which indicate the N-linked glycans in tACE to be mostly of the biantennary, fucosylated complex type. Glycopeptides 24-37 ADAM metallopeptidase domain 17 Homo sapiens 118-122 9299760-2 1997 In order to establish detailed fragmentation patterns and to dissect fragment ions with and without carbohydrate content, the same O-linked MUC1-derived glycopeptides with acetylated and non-acetylated sugars were analysed and compared. Glycopeptides 153-166 mucin 1, cell surface associated Homo sapiens 140-144 8910378-1 1996 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1-->6fucosyltransferase (alpha1-6FucT; EC 2.4.1.68), which catalyzes the transfer of fucose from GDP-Fuc to N-linked type complex glycopeptides, was purified from a Triton X-100 extract of porcine brain microsomes. Glycopeptides 178-191 fucosyltransferase 8 Rattus norvegicus 40-71 8910378-1 1996 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1-->6fucosyltransferase (alpha1-6FucT; EC 2.4.1.68), which catalyzes the transfer of fucose from GDP-Fuc to N-linked type complex glycopeptides, was purified from a Triton X-100 extract of porcine brain microsomes. Glycopeptides 178-191 fucosyltransferase 8 Rattus norvegicus 73-85 9133635-1 1997 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide:alpha1-6 fucosyltransferase (alpha1-6 FucT), which catalyzes the transfer of fucose from GDP-Fuc to N-linked type complex glycopeptides, was purified from a culture supernatant of human gastric cancer cell line MKN45. Glycopeptides 162-175 fucosyltransferase 8 Homo sapiens 0-67 9133635-1 1997 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide:alpha1-6 fucosyltransferase (alpha1-6 FucT), which catalyzes the transfer of fucose from GDP-Fuc to N-linked type complex glycopeptides, was purified from a culture supernatant of human gastric cancer cell line MKN45. Glycopeptides 162-175 fucosyltransferase 8 Homo sapiens 69-82 8981985-4 1997 Transcription of cat and vanX was inducible by glycopeptides in partial diploids harboring vanS and vanS(omega)cat but was constitutive in strains containing only vanS(omega)cat. Glycopeptides 47-60 VanX protein Enterococcus faecium 25-29 8981985-4 1997 Transcription of cat and vanX was inducible by glycopeptides in partial diploids harboring vanS and vanS(omega)cat but was constitutive in strains containing only vanS(omega)cat. Glycopeptides 47-60 VanS protein Enterococcus faecium 91-95 8981985-4 1997 Transcription of cat and vanX was inducible by glycopeptides in partial diploids harboring vanS and vanS(omega)cat but was constitutive in strains containing only vanS(omega)cat. Glycopeptides 47-60 VanS protein Enterococcus faecium 100-104 8981985-4 1997 Transcription of cat and vanX was inducible by glycopeptides in partial diploids harboring vanS and vanS(omega)cat but was constitutive in strains containing only vanS(omega)cat. Glycopeptides 47-60 VanS protein Enterococcus faecium 100-104 8828507-3 1996 Exposure of the cells to a culture temperature of 37 C, compared to 33 C, had a fast and irreversibly suppressive effect on the levels of an abundant epididymal messenger RNA (mRNA), CE5, which represents the canine counterpart of the human CD52/HE5 mRNA, encoding a major glycosylphoshatidylinnositol (GPI)-anchored sperm membrane glycopeptide. Glycopeptides 332-344 CD52 molecule Canis lupus familiaris 183-186 8756692-9 1996 Chymotryptic cleavage in the pig AE2 Z-loop produced C-terminal glycopeptides. Glycopeptides 64-77 solute carrier family 4 member 2 Sus scrofa 33-36 8889826-0 1996 Estimation of the number of O-linked oligosaccharides per heavy chain of human serum IgA1 by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS) analysis of the hinge glycopeptide. Glycopeptides 206-218 immunoglobulin heavy constant alpha 1 Homo sapiens 85-89 8889826-4 1996 In order to determine the number of linked sugar chains, we applied matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS) to the hinge glycopeptide prepared from human serum IgA1. Glycopeptides 172-184 immunoglobulin heavy constant alpha 1 Homo sapiens 211-215 8889826-12 1996 The reason why only four out of five sites on the hinge glycopeptide were fully glycosylated in the IgA1 from the IgA1 myeloma patient is not clear. Glycopeptides 56-68 immunoglobulin heavy constant alpha 1 Homo sapiens 100-104 8889826-12 1996 The reason why only four out of five sites on the hinge glycopeptide were fully glycosylated in the IgA1 from the IgA1 myeloma patient is not clear. Glycopeptides 56-68 immunoglobulin heavy constant alpha 1 Homo sapiens 114-118 8626722-7 1996 The immobilized calreticulin proved to be a highly effective tool for sorting out monoglucosylated polymannose oligosaccharides or glycopeptides from complex mixtures of processing intermediates. Glycopeptides 131-144 calreticulin Homo sapiens 16-28 9387790-4 1996 These results suggest that the carbohydrate moiety of hCG participate in the signal transduction among receptor, G-protein and adenylatecyclase which is inhibited by Asn-linked oligosaccharide chains from ovalbumin glycopeptides. Glycopeptides 215-228 hypertrichosis 2 (generalised, congenital) Homo sapiens 54-57 8869094-14 1996 Our preliminary clinical results suggest that a humoral immune response to PEM protects against disease progression, and further support the idea of using synthetic peptides or glycopeptides containing the immunogenic core of the mucin as cancer vaccines. Glycopeptides 177-190 mucin 1, cell surface associated Homo sapiens 75-78 8799292-1 1996 The fraction of sulphated oligosaccharide alditols isolated from mucin glycopeptides of porcine small intestine "insoluble" mucin complex was analysed by negative-ion fast atom bombardment (FAB) tandem mass spectrometry. Glycopeptides 71-84 LOC100508689 Homo sapiens 65-70 8631778-10 1996 1H NMR spectroscopy and electrospray ionization-mass spectrometry showed that the LEC14 core glycopeptides contain a new GlcNAc residue that substitutes the core beta(1-4)-Man residue at O-2 to give the following novel, N-linked core structure. Glycopeptides 93-106 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 162-170 8758482-1 1996 Glycopeptides which have excellent in vitro activity against the Gram-positive causal agents of meningitis unfortunately have a poor CSF penetration. Glycopeptides 0-13 colony stimulating factor 2 Homo sapiens 133-136 11667093-1 1996 The selective C-terminal deprotection of O-glycopeptide (methoxyethoxy)ethyl esters is achieved under mild conditions (pH 6.6, 37 degrees C) by enzymatic hydrolysis using papain or lipase M from Mucor javanicus to give building blocks useful for chain-extending glycopeptide synthesis. Glycopeptides 43-55 probable feruloyl esterase A Triticum aestivum 181-187 11667093-2 1996 On the other hand, the selective removal of acetyl protecting groups from the saccharide portion of glycopeptides is accomplished by alternative enzymatic hydrolysis with lipase WG from wheat germ to furnish model substrates for enzymatic glycosyl transfer reactions in order to extend the carbohydrate side chain of these conjugates. Glycopeptides 100-113 probable feruloyl esterase A Triticum aestivum 171-177 8605919-6 1996 With two of these glycopeptides, with galabiose (Gal alpha 1-4Gal; Gal2) bound to a homocysteine (via an ethylene spacer arm) in position 4 or 6 in a vesicular stomatitis virus nucleoprotein-derived peptide (RGYVYQGL binding to Kb), CTL were generated which preferentially killed target cells treated with glycopeptide compared to those treated with the core peptide. Glycopeptides 18-31 lectin, galactose-binding, soluble 2 Mus musculus 67-71 8850552-3 1996 These sequences are nearly identical to the two human fibrinogen glycopeptides, Val-Glu-Asn(CHO)-Lys (gamma-chain), and Met-Gly-Glu-Asn(CHO)-Arg (beta-chain). Glycopeptides 65-78 fibrinogen beta chain Homo sapiens 54-64 8605919-6 1996 With two of these glycopeptides, with galabiose (Gal alpha 1-4Gal; Gal2) bound to a homocysteine (via an ethylene spacer arm) in position 4 or 6 in a vesicular stomatitis virus nucleoprotein-derived peptide (RGYVYQGL binding to Kb), CTL were generated which preferentially killed target cells treated with glycopeptide compared to those treated with the core peptide. Glycopeptides 18-30 lectin, galactose-binding, soluble 2 Mus musculus 67-71 8641764-3 1996 The agglutination reaction was specifically inhibited by glycopeptides derived from bovine lactoferrin or alpha-methyl-D-mannoside. Glycopeptides 57-70 lactotransferrin Bos taurus 91-102 8825618-0 1996 Inhibition of human immunodeficiency virus infection of CD4+ cells by CD4-free glycopeptides from monocytic U937 cells. Glycopeptides 79-92 CD4 molecule Homo sapiens 56-59 8742080-0 1996 Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry. Glycopeptides 59-72 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 41-49 8742080-5 1996 In this report, synthetic glycopeptides were generated and used to demonstrate that O-GlcNAc-modified peptides can be rapidly identified in complex mixtures by HPLC-coupled electrospray mass spectrometry due to the partial loss of the O-linked glycan (204 amu) at a modest orifice potential. Glycopeptides 26-39 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 84-92 8825618-0 1996 Inhibition of human immunodeficiency virus infection of CD4+ cells by CD4-free glycopeptides from monocytic U937 cells. Glycopeptides 79-92 CD4 molecule Homo sapiens 70-73 8825618-3 1996 CD4-free tryptic glycopeptides, prepared from the membrane of CD4+ monocytic U937 cells and partially purified by ConA-agarose affinity chromatography, could be eluted by mannan but not by methyl-alpha-mannose or methyl-alpha-glucose, which strongly suggests that they displayed oligomannosidic structures. Glycopeptides 17-30 CD4 molecule Homo sapiens 0-3 8825618-3 1996 CD4-free tryptic glycopeptides, prepared from the membrane of CD4+ monocytic U937 cells and partially purified by ConA-agarose affinity chromatography, could be eluted by mannan but not by methyl-alpha-mannose or methyl-alpha-glucose, which strongly suggests that they displayed oligomannosidic structures. Glycopeptides 17-30 CD4 molecule Homo sapiens 62-65 7559574-4 1995 The larger of these (17 kDa) begins at Gln-209 near the end of the carbonic anhydrase-like domain of phosphacan/RPTP zeta/beta, whereas a 13-kDa glycopeptide begins at His-361 located in the middle of the fibronectin type III-like domain. Glycopeptides 145-157 protein tyrosine phosphatase receptor type Z1 Homo sapiens 101-111 8834812-7 1996 Glycopeptides obtained from [3H]galactose-labelled cells bind to VIP36 and can be eluted with N-acetyl-D-galactosamine. Glycopeptides 0-13 lectin, mannose binding 2 Canis lupus familiaris 65-70 8556161-7 1995 By reversed-phase HPLC of tryptic digested neuraminidase treated rFVIIa the glycopeptides containing the heavy chain N-glycosylated site elute as two peaks compared to the four peaks corresponding to glycopeptides with 0 to 3 N-acetyl-neuraminic acids seen for untreated rFVIIa. Glycopeptides 76-89 neuraminidase 1 Homo sapiens 43-56 8770386-5 1995 It is suggested that dimeric SLex glycopeptides of the mucin type would be effective ligands for E-selectin. Glycopeptides 34-47 selectin E Homo sapiens 97-107 7559574-6 1995 Based on the amino acid sequence of phosphacan, it can be concluded that each of the tryptic peptides contains one potential N-glycosylation site (at Asn-232 and Asn-381), and analyses of the isolated glycopeptides demonstrated the presence of sialylated complex-type oligosaccharides. Glycopeptides 201-214 protein tyrosine phosphatase receptor type Z1 Homo sapiens 36-46 8595249-9 1995 Immune responses generated by these synthetic glycopeptides are highly specific in recognizing the native cancer associated mucin. Glycopeptides 46-59 LOC100508689 Homo sapiens 124-129 9158786-3 1995 In 5 of 13 samples of raw minced meat of pigs originating from 13 different butcher"s shops, glycopeptide-resistant E. faecium (VanA type) could be detected after overnight broth cultivation of these samples. Glycopeptides 93-105 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 128-132 7626668-4 1995 Glycopeptides prepared from the N-terminal region of glycophorin A containing most of the sialosaccharide chains of the molecule inhibited the binding of ox-LDL although the potency was lower than that of glycophorin A. Glycopeptides 0-13 glycophorin A Mus musculus 53-66 7545084-6 1995 Binding of BW835 to glycopeptide 17 or to MUC1 was competitively inhibited by peanut agglutinin and by the synthetic glycopeptides TF alpha Ser or TF alpha Thr but not by their beta-anomers. Glycopeptides 117-130 mucin 1, cell surface associated Homo sapiens 42-46 7626668-4 1995 Glycopeptides prepared from the N-terminal region of glycophorin A containing most of the sialosaccharide chains of the molecule inhibited the binding of ox-LDL although the potency was lower than that of glycophorin A. Glycopeptides 0-13 glycophorin A Mus musculus 205-218 7795415-1 1995 A method for the separation of O-linked oligosaccharides into neutral, sialic acid-containing and sulfated species was applied to oligosaccharides released by alkaline borohydride from mucin glycopeptides from porcine small intestine. Glycopeptides 191-204 LOC100508689 Homo sapiens 185-190 8572267-5 1995 Next, RCA I was used to isolate glycopeptides from the O-GlcNAc-bearing basic phosphoprotein (BPP) of human cytomegalovirus. Glycopeptides 32-45 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 55-63 7786020-2 1995 PNGase activities were determined using 14C-labeled fetuin glycopeptide I as a substrate by a newly improved enzyme assay based on the paper chromatographic and paper electrophoretic analyses. Glycopeptides 59-71 N-glycanase 1 Mus musculus 0-6 7496141-5 1995 A galactose-terminated triantennary N-glycoside, having one N-acetyl-lactosamine unit on the 6 branch and two N-acetyl-lactosamine units on the 3 branch of the trimannosyl core structure, showed affinity enhancement of approximately 10(5) over a monovalent ligand for HHL, while the same glycopeptide showed enhancement of about 2000-fold for rM-ASGP-BP. Glycopeptides 288-300 C-type lectin domain containing 10A Rattus norvegicus 343-353 7613477-2 1995 A recently described mass spectrometric technique involving monitoring of carbohydrate-specific fragment ions during HPLC/ESIMS was employed to locate eight different groups of glycopeptides in a digest of a human LCAT protein preparation. Glycopeptides 177-190 lecithin-cholesterol acyltransferase Homo sapiens 214-218 7613477-3 1995 In addition to the four expected N-linked glycopeptides of LCAT, a di-O-linked glycopeptide was detected, as well as three additional glycopeptides. Glycopeptides 42-55 lecithin-cholesterol acyltransferase Homo sapiens 59-63 7768507-3 1995 Both native mucin and glycopeptides bound to mature HAP crystals, but the glycopeptides were much more readily displaced by phosphate ions. Glycopeptides 74-87 LOC100508689 Homo sapiens 12-17 7872492-5 1995 It is believed that cathepsin D plays a main role in the degradation of rod outer segments and rhodopsin into glycopeptides. Glycopeptides 110-123 rhodopsin Rattus norvegicus 95-104 7710067-3 1995 Desialylation and beta-galactosidase digestion conditions were developed to produce asialo- and asialo-agalacto glycopeptides. Glycopeptides 112-125 galactosidase beta 1 Bos taurus 18-36 7733455-3 1995 The method was applied on a mixture of neutral oligosaccharides released from mucin glycopeptides of rat small intestine by alkaline borohydride. Glycopeptides 84-97 solute carrier family 13 member 2 Rattus norvegicus 78-83 9346848-5 1995 While alpha-linked glycopeptides can bind to MHC without major alterations in the spatial arrangements and hydrogen bonding pattern of class II-peptide binding, the binding of beta-linked glycopeptides is considerably less favorable due to steric and columbic conflicts. Glycopeptides 19-32 major histocompatibility complex, class I, C Homo sapiens 45-48 7872492-5 1995 It is believed that cathepsin D plays a main role in the degradation of rod outer segments and rhodopsin into glycopeptides. Glycopeptides 110-123 cathepsin D Rattus norvegicus 20-31 9346848-0 1995 Computer design of T-cell agonist or antagonist glycopeptides: the effect of sugar identity and anomeric configuration on MHC binding. Glycopeptides 48-61 major histocompatibility complex, class I, C Homo sapiens 122-125 7966627-7 1994 Furthermore, the major sites of O-GlcNAc attachment to the rBPP were mapped on high-performance liquid chromatography-purified glycopeptides by gas phase microsequencing, manual Edman degradation, and electrospray-mass spectrometry. Glycopeptides 127-140 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 32-40 7551253-2 1995 This provides the basis for our development of synthetic carbohydrate, peptide, and glycopeptide-based ASI agents corresponding to the cancer-associated mucin epitopes. Glycopeptides 84-96 LOC100508689 Homo sapiens 153-158 7757427-6 1994 Glycopeptides containing N-glycans derived from lamp-1 were fractionated by sequential lectin affinity chromatography. Glycopeptides 0-13 lysosome-associated membrane glycoprotein 1 Cricetulus griseus 48-54 7864366-0 1994 Analysis by electrospray mass spectrometry of glycopeptides from the in vitro O-glycosylation reaction using human mucin motif peptide. Glycopeptides 46-59 LOC100508689 Homo sapiens 115-120 7873664-12 1994 These data demonstrate that the YEE(GalNAcAH)3 synthetic glycopeptide can be used as a ligand in targeted delivery of DNA to the liver-specific ASGPr. Glycopeptides 57-69 asialoglycoprotein receptor 1 Homo sapiens 144-149 7854121-7 1994 These results establish that VanX is required for production of a D,D-dipeptidase that hydrolyses D-Ala-D-Ala, thereby preventing pentapeptide synthesis and subsequent binding of glycopeptides to D-Ala-D-Ala-containing peptidoglycan precursors at the cell surface. Glycopeptides 179-192 VanX Enterococcus faecalis 29-33 7854121-1 1994 Cloning and nucleotide sequencing indicated that transposon Tn1546 from Enterococcus faecium BM4147 encodes a 23,365 Da protein, VanX, required for glycopeptide resistance. Glycopeptides 148-160 VanX protein Enterococcus faecium 129-133 8181460-3 1994 Most glycopeptides were excellent substrates for core 1 beta 3-Gal-T compared to benzyl alpha-D-galactosamine as indicated by their relatively high Vmax/Km. Glycopeptides 5-18 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 Rattus norvegicus 49-68 7921174-5 1994 A 1-h gas-phase hydrolysis time seems to be appropriate for the majority of glycopeptides and 1.5 h is suitable for the majority of phosphopeptides. Glycopeptides 76-89 BCL2 related protein A1 Homo sapiens 0-3 8034696-5 1994 The O-GlcNAcase also shows substantially stronger relative activity against O-GlcNAc-synthetic glycopeptides than other hexosaminidases. Glycopeptides 95-108 O-GlcNAcase Rattus norvegicus 4-15 8067523-8 1994 In the mapping of the CHO IL-4 glycoprotein, detection of the trypsin-generated glycopeptides was only possible by MALDI, where their detection was greatly improved by using the super-DHB (sDHB) matrix, a 9:1 mixture of 2,5-dihydroxybenzoic acid (DHB) with 2-hydroxy-5-methoxybenzoic acid. Glycopeptides 80-93 interleukin 4 Homo sapiens 26-30 8181460-2 1994 Series of glycopeptides have been synthesized by solid-phase synthesis, protected with an acetyl group on the amino terminal and an amide group on the carboxy terminal, based on variations of the repeat sequences of human intestinal mucin. Glycopeptides 10-23 LOC100508689 Homo sapiens 233-238 8344946-5 1993 The predominant sites of O-GlcNAc attachment on NF-L and NF-M are identified using proteolysis, purification of the glycopeptides, and subsequent analysis by automated gas-phase sequencing, manual Edman degradation, and laser desorption mass spectrometry. Glycopeptides 116-129 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 25-33 7507111-6 1994 Thus O-glycosylation is likely to play an important role in controlling the fate of the NH2-terminal portion of pro-opiomelanocortin, thereby affecting the biological events that are influenced by peptides and glycopeptides derived from this domain. Glycopeptides 210-223 proopiomelanocortin Bos taurus 112-132 8373354-2 1993 A rat intestinal lambda ZAP II cDNA library was screened using a polyclonal antiserum which was prepared against deglycosylated high-molecular-mass glycopeptides of the purified mucin. Glycopeptides 148-161 solute carrier family 13 member 2 Rattus norvegicus 178-183 8168955-9 1994 These bands were partially or completely displaced by nonradiolabeled respiratory mucin glycopeptides but not by tetramethylurea, suggesting that they recognized carbohydrate sites. Glycopeptides 88-101 LOC100508689 Homo sapiens 82-87 8360471-0 1993 Glycopeptides bind MHC molecules and elicit specific T cell responses. Glycopeptides 0-13 major histocompatibility complex, class I, C Homo sapiens 19-22 8360471-9 1993 T cells directed to Gal2-52-61 recognized glycopeptides having significant variation in the disaccharide structure, such as HEL(52-61) glycopeptides carrying lactose, cellobiose, or hepta-o-acetylated galabiose. Glycopeptides 42-55 galectin 2 Homo sapiens 20-24 8360471-9 1993 T cells directed to Gal2-52-61 recognized glycopeptides having significant variation in the disaccharide structure, such as HEL(52-61) glycopeptides carrying lactose, cellobiose, or hepta-o-acetylated galabiose. Glycopeptides 135-148 galectin 2 Homo sapiens 20-24 8344946-5 1993 The predominant sites of O-GlcNAc attachment on NF-L and NF-M are identified using proteolysis, purification of the glycopeptides, and subsequent analysis by automated gas-phase sequencing, manual Edman degradation, and laser desorption mass spectrometry. Glycopeptides 116-129 neurofilament light chain Homo sapiens 48-52 8344946-5 1993 The predominant sites of O-GlcNAc attachment on NF-L and NF-M are identified using proteolysis, purification of the glycopeptides, and subsequent analysis by automated gas-phase sequencing, manual Edman degradation, and laser desorption mass spectrometry. Glycopeptides 116-129 neurofilament medium chain Homo sapiens 57-61 1456441-10 1992 The SNA-bound glycopeptides were further fractionated by LPHA affinity chromatography. Glycopeptides 14-27 secretoglobin family 1D member 1 Homo sapiens 57-61 8419650-7 1993 Fragmentation of the gp120-derived 35SO4-labeled glycopeptides by treatment with hydrazine and nitrous acid and subsequent reduction generated galactosyl-anhydromannitol-6-35SO4, which is the expected reaction product from GlcNAc-6-sulfate within a sulfated lactosamine moiety. Glycopeptides 49-62 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 21-26 8419650-8 1993 Charge analysis of the [3H]galactose- and [3H]glucosamine-labeled glycopeptides from gp120 and gp160 indicates that approximately 14% of the complex-type N-linked oligosaccharides are sulfated. Glycopeptides 66-79 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 85-90 8400551-3 1993 The amino acid sequence data demonstrated that the glycopeptides were derived from rhodopsin and confirmed the presence of two N-glycosylation sites, at residues Asn2 and Asn15. Glycopeptides 51-64 rhodopsin Homo sapiens 83-92 7685744-6 1993 Computer modeling of the MUC-1 immunoreactive glycopeptide containing the H type-3 trisaccharide alpha Fuc 1-2 beta Gal 1-3 alpha GalNAc- bound to the threonine of the PDTRP-pentapeptide shows that the peptide epitope might be masked when the fucose is positioned over the arginine. Glycopeptides 46-58 mucin 1, cell surface associated Homo sapiens 25-30 8448122-0 1993 Structure and dynamics of mucin-like glycopeptides. Glycopeptides 37-50 LOC100508689 Homo sapiens 26-31 8448122-12 1993 These changes are consistent with the extrapolations of the mucin chain dimension data to glycopeptides of this size. Glycopeptides 90-103 LOC100508689 Homo sapiens 60-65 1445223-9 1992 In addition, the N-terminal amino acid sequence of the larger glycopeptide was found to be part of one of the selected MG2 cDNA clones. Glycopeptides 62-74 mucin 7, secreted Homo sapiens 119-122 1418987-7 1992 Purified O-glycopeptides were characterized with respect to amino acid and carbohydrate compositions and sequenced by automated Edman degradation; alpha OGP was a 41-residue glycopeptide with three O-linked sugar chains. Glycopeptides 11-23 oviductal glycoprotein 1 Mus musculus 153-156 1419961-1 1992 study of interaction between sugar and peptide moieties in mucin-type model glycopeptides. Glycopeptides 76-89 LOC100508689 Homo sapiens 59-64 1418987-8 1992 Sequence comparisons revealed a 75% identity between alpha OGP and a corresponding segment of rabbit rec55 zona protein; beta OGP was a 25-residue glycopeptide characterized by the presence of one N-linked and five O-linked sugar chains and a trypsin-resistant internal arginine residue. Glycopeptides 147-159 oviductal glycoprotein 1 Mus musculus 126-129 1346959-0 1992 Interaction between secretory leucocyte proteinase inhibitor and bronchial mucins or glycopeptides. Glycopeptides 85-98 endogenous retrovirus group K member 25 Homo sapiens 40-50 1346959-2 1992 The interaction of secretory leucocyte proteinase inhibitor with bronchial mucins and glycopeptides was studied by means of c.d. Glycopeptides 86-99 endogenous retrovirus group K member 25 Homo sapiens 39-49 1346959-8 1992 Glycopeptides treated with neuraminidase gave similar profiles of difference spectra in three different mixtures, indicating that the interaction was smaller. Glycopeptides 0-13 neuraminidase 1 Homo sapiens 27-40 1822238-1 1991 In this paper we report the first application of fast atom bombardment mass spectrometry (FAB-MS) to O-linked N-acetylglucosamine (O-GlcNAc)-bearing glycopeptides. Glycopeptides 149-162 FA complementation group B Homo sapiens 90-93 1587263-5 1992 The staining procedure is also used following isoelectric focusing of mucin-derived glycopeptides to visualize their charge differences and the increase of their isoelectric point after neuraminidase treatment. Glycopeptides 84-97 LOC100508689 Homo sapiens 70-75 1587263-5 1992 The staining procedure is also used following isoelectric focusing of mucin-derived glycopeptides to visualize their charge differences and the increase of their isoelectric point after neuraminidase treatment. Glycopeptides 84-97 neuraminidase 1 Homo sapiens 186-199 1822238-1 1991 In this paper we report the first application of fast atom bombardment mass spectrometry (FAB-MS) to O-linked N-acetylglucosamine (O-GlcNAc)-bearing glycopeptides. Glycopeptides 149-162 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 131-139 1822238-8 1991 The propionylation/FAB-MS procedure has been combined with gas-phase sequencing strategies and shows promise for defining the sites of glycosylation of O-GlcNAc glycopeptides that are available in limited quantities. Glycopeptides 161-174 FA complementation group B Homo sapiens 19-22 1822238-8 1991 The propionylation/FAB-MS procedure has been combined with gas-phase sequencing strategies and shows promise for defining the sites of glycosylation of O-GlcNAc glycopeptides that are available in limited quantities. Glycopeptides 161-174 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 152-160 1822238-2 1991 Using N-acetylgalactosamine (GalNAc)- and Gal-GalNAc-containing glycopeptides (isolated from Tn glycophorin and desialylated normal glycophorin, respectively) as readily available model compounds, rapid and sensitive derivatization/FAB-MS strategies applicable to serine/threonine-rich glycopeptides have been devised. Glycopeptides 64-77 FA complementation group B Homo sapiens 232-235 1822238-3 1991 Peptides and glycopeptides were propionylated in a 1 min reaction using a mixture of trifluoroacetic anhydride and propionic acid, and the product mixtures were analysed directly by FAB-MS. Glycopeptides and peptides rich in hydroxylated residues afforded characteristic clusters of molecular ions at high sensitivity. Glycopeptides 190-203 FA complementation group B Homo sapiens 182-185 1822238-5 1991 These methods were used in a study of O-GlcNAc glycopeptides produced by purified O-GlcNAc transferase addition of GlcNAc to the synthetic peptides YSDSPSTST and YSGSPSTST in which Y is tyrosine, S is serine, D is aspartic acid, P is proline, T is threonine and G is glycine. Glycopeptides 47-60 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 38-46 1823621-1 1991 The fibronectin fragment VTHPGY and the corresponding glycopeptides V(Gal beta 3GalNAc alpha)THPGY and V(Gal beta 3GalNAc beta)THPGY were synthesized by the FMOC/solid phase approach. Glycopeptides 54-67 fibronectin 1 Homo sapiens 4-15 1822238-5 1991 These methods were used in a study of O-GlcNAc glycopeptides produced by purified O-GlcNAc transferase addition of GlcNAc to the synthetic peptides YSDSPSTST and YSGSPSTST in which Y is tyrosine, S is serine, D is aspartic acid, P is proline, T is threonine and G is glycine. Glycopeptides 47-60 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 82-90 2045542-9 1991 Although these extended regions do not contain a glycosylation site, they show striking similarity with the glycopeptide moiety (copeptin) of toad vasotocin and mammalian vasopressin precursors. Glycopeptides 108-120 arginine vasopressin Homo sapiens 171-182 1712019-4 1991 On treatment with V8 protease, GP-I was converted to two glycopeptides, one with poor reactivity and the other with intermediate reactivity. Glycopeptides 57-70 glucose-6-phosphate isomerase Homo sapiens 31-35 2052617-10 1991 We conclude that in newborn rat kidney (i) podocalyxin contains both O- and N-linked oligosaccharides [high mannose or hybrid type, biantennary, and complex (sialylated) type], (ii) podocalyxin is sulfated, and (iii) sulfate is located on both O-linked oligosaccharides and on glycopeptides carrying tri- or tetrantennary N-linked structures. Glycopeptides 277-290 podocalyxin-like Rattus norvegicus 182-193 1723282-6 1991 In the CH-eluted fraction, 50 and 52 kDa glycopeptides were revealed by ConA and WGA, whereas in the CE-immunopurified fraction no band was visualized. Glycopeptides 41-54 CONA Bos taurus 72-76 2243102-5 1990 The poly-N-acetyllactosaminyl structures of isolated glycopeptides were confirmed by the susceptibility of their released oligosaccharides to endo-beta-galactosidase. Glycopeptides 53-66 galactosidase beta 1 Homo sapiens 147-165 2224891-3 1990 Ester groups were removed from the carbohydrate moieties with methanolic hydrazine, to give the TN and T antigen glycopeptides which were coupled to bovine serum albumin (BSA) via a carbodi-imide procedure and without any spacer groups. Glycopeptides 113-126 albumin Homo sapiens 156-169 2150408-4 1990 Calcium ionophore-induced degranulation of beta-glucuronidase and elastase were slightly impaired (Student two-tailed; P less than 0.1) by both glycopeptides (beta-glucuronidase) and teicoplanin only (elastase). Glycopeptides 144-157 glucuronidase beta Homo sapiens 43-61 2211711-6 1990 The inhibitory potency of a variety of complex glycopeptides against radiolabeled ligand binding to both rat hepatocytes and soluble lectin are in agreement with photoaffinity results that galactose 8 of triantennary glycopeptide is of unique importance by binding solely to the minor subunits (RHL2/3) of the asialoglycoprotein receptor on hepatocytes. Glycopeptides 47-60 asialoglycoprotein receptor 2 Rattus norvegicus 295-299 2211711-6 1990 The inhibitory potency of a variety of complex glycopeptides against radiolabeled ligand binding to both rat hepatocytes and soluble lectin are in agreement with photoaffinity results that galactose 8 of triantennary glycopeptide is of unique importance by binding solely to the minor subunits (RHL2/3) of the asialoglycoprotein receptor on hepatocytes. Glycopeptides 47-59 asialoglycoprotein receptor 2 Rattus norvegicus 295-299 2223825-10 1990 The lectin profiles obtained for the complex N-glycans of the transferrin receptor glycopeptides were similar to those for the total cellular glycopeptides of NS-1 cells. Glycopeptides 83-96 transferrin Mus musculus 62-73 2223825-11 1990 Reverse-phase HPLC analysis of tryptic glycopeptides of the isolated [3H]mannose-labelled transferrin receptor gave three 3H-labelled peaks, indicating that all three potential N-glycosylation sites on the receptor are utilised. Glycopeptides 39-52 transferrin Mus musculus 90-101 2148751-0 1990 Vasopressin in the brain of the golden hamster: the distribution of vasopressin binding sites and of immunoreactivity to the vasopressin-related glycopeptide. Glycopeptides 145-157 arginine vasopressin Rattus norvegicus 0-11 2148751-0 1990 Vasopressin in the brain of the golden hamster: the distribution of vasopressin binding sites and of immunoreactivity to the vasopressin-related glycopeptide. Glycopeptides 145-157 arginine vasopressin Rattus norvegicus 125-136 2291654-11 1990 The vanA gene was not detected in the glycopeptide-producing strains of Amycolatopsis orientalis (vancomycin) and Actinoplanes teichomyceticus (teicoplanin) or in various gram-positive bacteria intrinsically resistant to glycopeptides. Glycopeptides 221-234 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 4-8 2400992-0 1990 Evidence that high mannose glycopeptides are able to functionally interact with recombinant tumor necrosis factor and recombinant interleukin 1. Glycopeptides 27-40 tumor necrosis factor Mus musculus 92-113 2400992-0 1990 Evidence that high mannose glycopeptides are able to functionally interact with recombinant tumor necrosis factor and recombinant interleukin 1. Glycopeptides 27-40 interleukin 1 complex Mus musculus 130-143 2395332-8 1990 Digestion of the glycopeptides with endo-beta-galactosidase, which specifically cleaves polylactosaminoglycans, showed the presence of material containing N-acetyllactosamine repeating units in Gaucher liver glycopeptide fractions, but not in control and Niemann-Pick type C derived glycopeptide fractions. Glycopeptides 17-29 galactosidase beta 1 Homo sapiens 41-59 2395332-8 1990 Digestion of the glycopeptides with endo-beta-galactosidase, which specifically cleaves polylactosaminoglycans, showed the presence of material containing N-acetyllactosamine repeating units in Gaucher liver glycopeptide fractions, but not in control and Niemann-Pick type C derived glycopeptide fractions. Glycopeptides 17-29 protein interacting with PRKCA 1 Homo sapiens 263-267 2395332-8 1990 Digestion of the glycopeptides with endo-beta-galactosidase, which specifically cleaves polylactosaminoglycans, showed the presence of material containing N-acetyllactosamine repeating units in Gaucher liver glycopeptide fractions, but not in control and Niemann-Pick type C derived glycopeptide fractions. Glycopeptides 208-220 galactosidase beta 1 Homo sapiens 41-59 2113054-9 1990 The disulfide bonds of sCD4 were determined to be within domains 1, 2, and 4 and isolation of glycopeptides showed that both N-linked sites were glycosylated. Glycopeptides 94-107 stearoyl-coenzyme A desaturase 4 Rattus norvegicus 23-27 2194988-2 1990 In retinal pigment epithelium, cathepsin D degrades rod outer segments and rhodopsin into glycopeptides. Glycopeptides 90-103 cathepsin D Bos taurus 31-42 2194988-2 1990 In retinal pigment epithelium, cathepsin D degrades rod outer segments and rhodopsin into glycopeptides. Glycopeptides 90-103 rhodopsin Bos taurus 75-84 6652065-3 1983 Exo- and endoglycosidase digestion, periodate oxidation, permethylation analysis, and lectin reactivity provided evidence for a tentative carbohydrate structure for the glycopeptide mixture. Glycopeptides 169-181 5'-3' exoribonuclease 1 Mus musculus 0-3 1694506-7 1990 In the present study we have shown that glycopeptides and oligosaccharides prepared from hCG, transferrin, fetuin, alpha 1-acid glycoprotein and ovalbumin inhibit the binding of hCG to its receptor. Glycopeptides 40-53 glycoprotein hormones, alpha polypeptide Homo sapiens 89-92 1694506-7 1990 In the present study we have shown that glycopeptides and oligosaccharides prepared from hCG, transferrin, fetuin, alpha 1-acid glycoprotein and ovalbumin inhibit the binding of hCG to its receptor. Glycopeptides 40-53 transferrin Homo sapiens 94-105 1694506-7 1990 In the present study we have shown that glycopeptides and oligosaccharides prepared from hCG, transferrin, fetuin, alpha 1-acid glycoprotein and ovalbumin inhibit the binding of hCG to its receptor. Glycopeptides 40-53 glycoprotein hormones, alpha polypeptide Homo sapiens 178-181 2106488-0 1990 In vitro inhibition of IL-2 biosynthesis in activated human peripheral blood mononuclear cells by a trauma-induced glycopeptide. Glycopeptides 115-127 interleukin 2 Homo sapiens 23-27 2335508-1 1990 Binding characteristics of human spleen soluble galactoside-binding protein (galaptin) were studied using simple galactosides, galactose-terminated disaccharides, cluster glycosides containing up to 6 terminal lactosyl residues, bovine serum albumin derivatives containing 7 to 40 lactosyl residues, desialylated serum glycoproteins, and glycopeptides derived thereof as inhibitors in a newly developed binding assay. Glycopeptides 338-351 galectin 1 Homo sapiens 77-85 2387072-5 1990 Glycopeptides derived from a glycoprotein, fibronectin, secreted from CF fibroblasts were also examined by 1H-NMR spectroscopy and showed no evidence of fucosyl residues linked alpha 1----3 to branch N-acetylglucosamine and a lesser percentage of core fucose than found in the peripheral membrane glycopeptides. Glycopeptides 0-13 fibronectin 1 Homo sapiens 43-54 34652821-7 2021 Compared to controls, 24% of glycopeptides had reduced abundance in PMM2-deficient fibroblasts, 46% of which improved upon treatment. Glycopeptides 29-42 phosphomannomutase 2 Homo sapiens 68-72 34840084-5 2022 As a result, GO@MPDA@Arg composites exhibited excellent enrichment performance for glycopeptides, containing good selectivity (IgG digests : BSA digests = 1:50, molar ratio), low detection limit for IgG digests (10 fmol muL-1), high loading capacity for IgG digests (200 mug mg-1), and good size exclusion (IgG digests : IgG : BSA = 1:100:100, mass ratio). Glycopeptides 83-96 mitochondrial ubiquitin ligase activator of NFKB 1 Mus musculus 220-225 34152412-7 2021 The variation in O-glycoforms was evaluated by estimating the molecular weights of IgA1 hinge glycopeptides using reversed-phase liquid chromatography (LC) and tandem mass spectrometry under electron-transfer/higher-energy collision dissociation (EThcD) fragmentation mode. Glycopeptides 94-107 immunoglobulin heavy constant alpha 1 Homo sapiens 83-87 34155551-0 2021 Simultaneous enrichment and separation of neutral and sialyl glycopeptides of SARS-CoV-2 spike protein enabled by dual-functionalized Ti-IMAC material. Glycopeptides 61-74 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 89-94 34102146-4 2022 Results identified haptoglobin as the protein associated with HexNAc4-Hex5-NeuAc2, thus directly linking glycan imaging with intact glycopeptide identification. Glycopeptides 132-144 haptoglobin Canis lupus familiaris 19-30 34780171-0 2021 ZIC-cHILIC-Based StageTip for Simultaneous Glycopeptide Enrichment and Fractionation toward Large-Scale N-Sialoglycoproteomics. Glycopeptides 43-55 Zic family member 1 Homo sapiens 0-3 34780171-3 2021 Here, we present the first implementation of zwitterionic hydrophilic interaction chromatography with the exposed choline group (ZIC-cHILIC) in StageTip for simultaneous enrichment and fractionation of intact glycopeptides. Glycopeptides 209-222 Zic family member 1 Homo sapiens 129-132 34780171-6 2021 Most importantly, the ZIC-cHILIC stepwise strategy demonstrated good reproducibility (>80% in triplicate analysis) as well as superior coverage of 4.6- to 12.0-fold and 2.1- to 35.6-fold more glycopeptides and sialoglycopeptides compared to conventional TiO2 and ZIC-HILIC, respectively. Glycopeptides 192-205 Zic family member 1 Homo sapiens 22-25 34364505-3 2021 Inspired by the prevalence of hydrophilic interaction chromatography for glycopeptide enrichment, a novel magnetic mesoporous silica nanomaterial (Fe3O4@mSiO2-TSG) with strongly hydrophilic property was developed through a one-pot method. Glycopeptides 73-85 twisted gastrulation BMP signaling modulator 1 Homo sapiens 159-162 34711323-4 2021 Owing to the complexity of the intact protein, information about EPO glycosylation is commonly derived from released glycan and glycopeptide analysis using mass spectrometry (MS). Glycopeptides 128-140 erythropoietin Homo sapiens 65-68 34695439-6 2021 Glycopeptide analysis confirmed the presence of the glucose-beta1,3-fucose product of B3GLCT on TSP1 in wildtype (WT) cells and its absence in KO cells. Glycopeptides 0-12 beta 3-glucosyltransferase Homo sapiens 86-92 34695439-6 2021 Glycopeptide analysis confirmed the presence of the glucose-beta1,3-fucose product of B3GLCT on TSP1 in wildtype (WT) cells and its absence in KO cells. Glycopeptides 0-12 thrombospondin 1 Homo sapiens 96-100 34192302-5 2021 In this study, we analyzed site-specific N-glycan structures of serum M2BP using Glyco-RIDGE (Glycan heterogeneity-based Relational IDentification of Glycopeptide signals on Elution profile) method. Glycopeptides 150-162 galectin 3 binding protein Homo sapiens 70-74 34812564-0 2021 The Development of Vaccines from Synthetic Tumor-Associated Mucin Glycopeptides and their Glycosylation-Dependent Immune Response. Glycopeptides 66-79 LOC100508689 Homo sapiens 60-65 34578474-0 2021 ZIC-cHILIC Functionalized Magnetic Nanoparticle for Rapid and Sensitive Glycopeptide Enrichment from <1 microL Serum. Glycopeptides 72-84 Zic family member 1 Homo sapiens 0-3 34092405-10 2021 Since the symptoms of ALG12-CDG are quite diverse, the combination of whole-exome sequencing and transferrin glycopeptide analysis with MS, can help diagnosis of ALG12-CDG. Glycopeptides 109-121 ALG12 alpha-1,6-mannosyltransferase Homo sapiens 22-27 34092405-10 2021 Since the symptoms of ALG12-CDG are quite diverse, the combination of whole-exome sequencing and transferrin glycopeptide analysis with MS, can help diagnosis of ALG12-CDG. Glycopeptides 109-121 transferrin Homo sapiens 97-108 34127537-6 2021 Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls. Glycopeptides 186-199 immunoglobulin heavy constant alpha 1 Homo sapiens 75-79 34127537-6 2021 Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls. Glycopeptides 186-199 CD79a molecule Homo sapiens 84-88 34127537-6 2021 Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls. Glycopeptides 186-199 IGAN1 Homo sapiens 92-96 34127537-6 2021 Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls. Glycopeptides 186-199 CD79a molecule Homo sapiens 209-212 34127537-10 2021 Finally, glycopeptides were a better predictor of IgAN and glomerular function than galactose-deficient IgA1 levels measured by lectin-based ELISA. Glycopeptides 9-22 IGAN1 Homo sapiens 50-54 34482887-7 2021 Combining with the inherent properties of COF structure, the established platform achieved simultaneous enrichment of phosphopeptides and glycopeptides with excellent selectivity (1:1:1000 M ratio of alpha-casein/IgG/BSA), high sensitivity (0.05 fmol/muL alpha-casein; 0.05 fmol/muL IgG), and good size-exclusion effect (alpha-casein digests/IgG digests/BSA, 1:1:500). Glycopeptides 138-151 tripartite motif containing 37 Homo sapiens 251-254 34482887-7 2021 Combining with the inherent properties of COF structure, the established platform achieved simultaneous enrichment of phosphopeptides and glycopeptides with excellent selectivity (1:1:1000 M ratio of alpha-casein/IgG/BSA), high sensitivity (0.05 fmol/muL alpha-casein; 0.05 fmol/muL IgG), and good size-exclusion effect (alpha-casein digests/IgG digests/BSA, 1:1:500). Glycopeptides 138-151 tripartite motif containing 37 Homo sapiens 279-282 34778211-8 2021 A total of 7,127 unique N-linked glycosite-containing intact glycopeptides (IGPs), 928 glycosites, and 442 glycoproteins were identified from FUT8KO and WT CHO cells. Glycopeptides 61-74 alpha-(1,6)-fucosyltransferase Cricetulus griseus 142-148 34375180-4 2022 Here, we describe the design and in vivo biological evaluation of three vaccine candidates based on MUC1 glycopeptides that comprise unnatural elements in their structure. Glycopeptides 105-118 mucin 1, transmembrane Mus musculus 100-104 34375180-8 2022 According to our data, the development of effective MUC1-based vaccines should use surrogates that mimic the conformational space of aberrantly glycosylated MUC1 glycopeptides found in tumors. Glycopeptides 162-175 mucin 1, transmembrane Mus musculus 52-56 34375180-8 2022 According to our data, the development of effective MUC1-based vaccines should use surrogates that mimic the conformational space of aberrantly glycosylated MUC1 glycopeptides found in tumors. Glycopeptides 162-175 mucin 1, transmembrane Mus musculus 157-161 35388920-0 2022 New enantioselective liquid chromatography method development and validation of dipeptidyl peptidase IV inhibitors using a macrocyclic glycopeptide (vancomycin) chiral stationary phase under polar ionic mode condition. Glycopeptides 135-147 dipeptidyl peptidase 4 Homo sapiens 80-103 34345007-0 2021 Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting. Glycopeptides 70-83 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 64-69 34345007-1 2021 We describe an analytical method for the identification, mapping and relative quantitation of glycopeptides from SARS-CoV-2 Spike protein. Glycopeptides 94-107 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 124-129 34345007-6 2021 In combination with MSMS and pseudo MS3, we have constructed a detailed mass-retention time database for Spike glycopeptides. Glycopeptides 111-124 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 105-110 34345007-7 2021 This database allows any accurate mass LC-MS laboratory to reliably identify and quantify Spike glycopeptides from a single overnight elastase digest in less than 90 minutes. Glycopeptides 96-109 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 90-95 34421504-1 2021 Sialidosis is a rare autosomal recessive disease that presents with progressive lysosomal storage of sialylated glycopeptides and oligosaccharides caused by homozygous or compound heterozygous sequence variants in the neuraminidase 1 (NEU1) gene. Glycopeptides 112-125 neuraminidase 1 Homo sapiens 218-233 34421504-1 2021 Sialidosis is a rare autosomal recessive disease that presents with progressive lysosomal storage of sialylated glycopeptides and oligosaccharides caused by homozygous or compound heterozygous sequence variants in the neuraminidase 1 (NEU1) gene. Glycopeptides 112-125 neuraminidase 1 Homo sapiens 235-239 34402270-5 2021 Then XIC peak shapes,standard deviation of peak area,and fold change were applied for further screening and 5 glycopeptides with significant differences in DCG and DHG were confirmed,which could serve as potential biomarkers for distinguishing DCG and DHG. Glycopeptides 110-123 X chromosome inactivation center Homo sapiens 5-8 34100586-0 2021 Dual-Functional Ti(IV)-IMAC Material Enables Simultaneous Enrichment and Separation of Diverse Glycopeptides and Phosphopeptides. Glycopeptides 95-108 C-C motif chemokine ligand 26 Homo sapiens 23-27 34100586-2 2021 In this work, we report a new approach to enable simultaneous enrichment and separation of glycopeptides, phosphopeptides, and mannose-6-phosphate (M6P) glycopeptides by using a dual-functional Ti(IV)-IMAC material. Glycopeptides 91-104 C-C motif chemokine ligand 26 Homo sapiens 201-205 34100586-6 2021 This is the first report on simultaneous enrichment and separation of neutral and sialyl glycopeptides, mono- and multi-phosphopeptides, and M6P glycopeptides via dual-functional Ti(IV)- IMAC, revealing novel insights into potential crosstalk among these important PTMs. Glycopeptides 89-102 C-C motif chemokine ligand 26 Homo sapiens 187-191 34100586-6 2021 This is the first report on simultaneous enrichment and separation of neutral and sialyl glycopeptides, mono- and multi-phosphopeptides, and M6P glycopeptides via dual-functional Ti(IV)- IMAC, revealing novel insights into potential crosstalk among these important PTMs. Glycopeptides 145-158 C-C motif chemokine ligand 26 Homo sapiens 187-191 34207451-5 2021 This platform utilizes an online purification of LC for sample desalting, and an in silico haptoglobin glycopeptide library constructed by combining peptides and N-glycans to readily identify glycopeptides. Glycopeptides 103-115 haptoglobin Homo sapiens 91-102 34207451-5 2021 This platform utilizes an online purification of LC for sample desalting, and an in silico haptoglobin glycopeptide library constructed by combining peptides and N-glycans to readily identify glycopeptides. Glycopeptides 192-205 haptoglobin Homo sapiens 91-102 34093861-5 2021 Through quantification analysis of intact glycopeptides, we found that the majority of core-fucosylated intact glycopeptides from folate receptor alpha (FOLR1) were up-regulated in the three HGF-treated cell lines. Glycopeptides 42-55 folate receptor alpha Homo sapiens 130-151 34093861-5 2021 Through quantification analysis of intact glycopeptides, we found that the majority of core-fucosylated intact glycopeptides from folate receptor alpha (FOLR1) were up-regulated in the three HGF-treated cell lines. Glycopeptides 42-55 folate receptor alpha Homo sapiens 153-158 34093861-5 2021 Through quantification analysis of intact glycopeptides, we found that the majority of core-fucosylated intact glycopeptides from folate receptor alpha (FOLR1) were up-regulated in the three HGF-treated cell lines. Glycopeptides 42-55 hepatocyte growth factor Homo sapiens 191-194 34093861-5 2021 Through quantification analysis of intact glycopeptides, we found that the majority of core-fucosylated intact glycopeptides from folate receptor alpha (FOLR1) were up-regulated in the three HGF-treated cell lines. Glycopeptides 111-124 folate receptor alpha Homo sapiens 130-151 34093861-5 2021 Through quantification analysis of intact glycopeptides, we found that the majority of core-fucosylated intact glycopeptides from folate receptor alpha (FOLR1) were up-regulated in the three HGF-treated cell lines. Glycopeptides 111-124 folate receptor alpha Homo sapiens 153-158 34093861-5 2021 Through quantification analysis of intact glycopeptides, we found that the majority of core-fucosylated intact glycopeptides from folate receptor alpha (FOLR1) were up-regulated in the three HGF-treated cell lines. Glycopeptides 111-124 hepatocyte growth factor Homo sapiens 191-194 34853246-5 2021 Here, we show that the DDRs observed as the phosphorylation of H2AX (gammaH2AX) and caspase-3-dependent apoptosis-induction are under critical control in the intestine of C57BL mice that were injected intraperitoneally with bleomycin, a natural glycopeptide used clinically as an antitumor agent. Glycopeptides 245-257 H2A.X variant histone Mus musculus 63-67 34853246-5 2021 Here, we show that the DDRs observed as the phosphorylation of H2AX (gammaH2AX) and caspase-3-dependent apoptosis-induction are under critical control in the intestine of C57BL mice that were injected intraperitoneally with bleomycin, a natural glycopeptide used clinically as an antitumor agent. Glycopeptides 245-257 H2A.X variant histone Mus musculus 69-78 34853246-5 2021 Here, we show that the DDRs observed as the phosphorylation of H2AX (gammaH2AX) and caspase-3-dependent apoptosis-induction are under critical control in the intestine of C57BL mice that were injected intraperitoneally with bleomycin, a natural glycopeptide used clinically as an antitumor agent. Glycopeptides 245-257 caspase 3 Mus musculus 84-93 35388920-1 2022 The direct separation of dipeptidyl peptidase IV (DPP-4) inhibitors such as Sitagliptin (STG), Linagliptin (LIG), and Saxagliptin (SAG) enantiomers in normal phase conditions have been achieved on immobilized polysaccharide-based chiral stationary phases (CSPs), as well as on the macrocyclic glycopeptide vancomycin chiral stationary phase (Chirobiotic V2) under polar ionic mode. Glycopeptides 293-305 dipeptidyl peptidase 4 Homo sapiens 25-48 35388920-1 2022 The direct separation of dipeptidyl peptidase IV (DPP-4) inhibitors such as Sitagliptin (STG), Linagliptin (LIG), and Saxagliptin (SAG) enantiomers in normal phase conditions have been achieved on immobilized polysaccharide-based chiral stationary phases (CSPs), as well as on the macrocyclic glycopeptide vancomycin chiral stationary phase (Chirobiotic V2) under polar ionic mode. Glycopeptides 293-305 dipeptidyl peptidase 4 Homo sapiens 50-55 35093648-5 2022 According to electrospray ionization mass spectrometry (ESI-MS) analysis, there are two types of glycopeptides in the mixture, TGase and non-enzymatic glycated counterparts. Glycopeptides 97-110 transglutaminase 1 Homo sapiens 127-132 35510762-3 2022 In this study, a novel hydrogel (denoted as ZIF-8/SAP) with a stable three-dimensional (3D) network structure and excellent hydrophilicity was successfully fabricated to capture glycopeptides with high efficiency. Glycopeptides 178-191 SH2 domain containing 1A Homo sapiens 50-53 35510762-5 2022 Inspired by the great enrichment performance of the as-prepared material toward glycopeptides, ZIF-8/SAP was further applied to capture glycopeptides from a real human serum sample. Glycopeptides 80-93 SH2 domain containing 1A Homo sapiens 101-104 35510762-5 2022 Inspired by the great enrichment performance of the as-prepared material toward glycopeptides, ZIF-8/SAP was further applied to capture glycopeptides from a real human serum sample. Glycopeptides 136-149 SH2 domain containing 1A Homo sapiens 101-104 35462306-0 2022 OGA activated glycopeptide-based nano-activator to activate PKM2 tetramerization for switching catabolic pathways and sensitizing chemotherapy resistance. Glycopeptides 14-26 O-GlcNAcase Homo sapiens 0-3 35420609-4 2022 In addition, Fe3O4@ILI-01@Ti4+ exhibits superior enrichment performance on synchronous enrichment of phosphopeptides/glycopeptides from beta-casein/HRP tryptic digests. Glycopeptides 117-130 casein beta Homo sapiens 136-147 35544340-6 2022 The general applicability and robustness of this approach are exemplified by efficient preparation of 16 well-defined SARS-CoV-2 O-glycopeptides, 4 complex MUC1 glycopeptides, and a 31-mer glycosylated glucagon-like peptide-1. Glycopeptides 161-174 mucin 1, cell surface associated Homo sapiens 156-160 35462306-0 2022 OGA activated glycopeptide-based nano-activator to activate PKM2 tetramerization for switching catabolic pathways and sensitizing chemotherapy resistance. Glycopeptides 14-26 pyruvate kinase M1/2 Homo sapiens 60-64 35462306-3 2022 Herein, we developed a glycopeptide-based PKM2 nano-activator, which could induce the tetramerization of PKM2 based on serine bonding to Domain C of PKM2. Glycopeptides 23-35 pyruvate kinase M1/2 Homo sapiens 42-46 35462306-3 2022 Herein, we developed a glycopeptide-based PKM2 nano-activator, which could induce the tetramerization of PKM2 based on serine bonding to Domain C of PKM2. Glycopeptides 23-35 pyruvate kinase M1/2 Homo sapiens 105-109 35462306-3 2022 Herein, we developed a glycopeptide-based PKM2 nano-activator, which could induce the tetramerization of PKM2 based on serine bonding to Domain C of PKM2. Glycopeptides 23-35 pyruvate kinase M1/2 Homo sapiens 149-153 35462306-5 2022 The glycopeptide assembled into nanoparticles under aqueous conditions and in the circulation, which in situ transformed into PKM2 nano-activator with nanofibrillar structure after specifically activated by O-GlcNAcase recognition upregulated in a wide range of human tumors. Glycopeptides 4-16 pyruvate kinase M1/2 Homo sapiens 126-130 35462306-5 2022 The glycopeptide assembled into nanoparticles under aqueous conditions and in the circulation, which in situ transformed into PKM2 nano-activator with nanofibrillar structure after specifically activated by O-GlcNAcase recognition upregulated in a wide range of human tumors. Glycopeptides 4-16 O-GlcNAcase Homo sapiens 207-218 35462306-6 2022 Moreover, the glycopeptide-based PKM2 nano-activator successfully accumulated at the tumor sites and boosted the chemo-drug sensitivity against prostate and breast cancers. Glycopeptides 14-26 pyruvate kinase M1/2 Homo sapiens 33-37 35462306-7 2022 Attributed to these intriguing results, the newly developed glycopeptide-based PKM2 nano-activator can be envisioned a promising candidate for the treatment of tumors by switching catabolic pathways. Glycopeptides 60-72 pyruvate kinase M1/2 Homo sapiens 79-83 35182004-4 2022 This material manifests excellent property in glycopeptides enrichment, with high selectivity (1:5000), low detection limit (0.1 fmol muL-1 ), high recovery rate (99.4 +- 0.5%) and good repeatability. Glycopeptides 46-59 mitochondrial E3 ubiquitin protein ligase 1 Homo sapiens 134-139 35572668-0 2022 Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 by Suppressing the Proteolytic Activity of Cathepsin L. Glycopeptides 0-12 cathepsin L Homo sapiens 113-124 35572668-3 2022 We previously reported that teicoplanin, a glycopeptide antibiotic that has been commonly used in the clinic to treat bacterial infection, significantly restrained the cell entry of Ebola virus, SARS-CoV, and MERS-CoV by specifically inhibiting the activity of cathepsin L (CTSL). Glycopeptides 43-55 cathepsin L Homo sapiens 261-272 35572668-3 2022 We previously reported that teicoplanin, a glycopeptide antibiotic that has been commonly used in the clinic to treat bacterial infection, significantly restrained the cell entry of Ebola virus, SARS-CoV, and MERS-CoV by specifically inhibiting the activity of cathepsin L (CTSL). Glycopeptides 43-55 cathepsin L Homo sapiens 274-278 35495706-10 2022 Further in silico analyses revealed that an IS1216E-based composite transposon was generated in SC1762-D, and it disrupted the vanH gene, likely affecting the structure and expression of the vanA gene cluster and resulting in resensitization to glycopeptides. Glycopeptides 245-258 VanH protein Enterococcus faecium 127-131 35496372-7 2022 Individual glycopeptide analysis found separation between the AD patients and controls on complement proteins and apolipoprotein B. Glycopeptides 11-23 apolipoprotein B Homo sapiens 114-130 35573732-6 2022 Glycoproteomic analysis revealed the abundance of glycopeptides from LAMP2, NICA, and CEIP2 was significantly changed during NGI-1 treatment. Glycopeptides 50-63 lysosomal associated membrane protein 2 Homo sapiens 69-74 35350332-9 2022 By cross-comparison with our previous urinary glycoproteomic dataset for aggressive prostate cancer, we reported a total of four glycopeptides from glycoproteins DSC2, MGAM, PIK3IP1, and CD55, commonly identified to be prostate cancer-specific. Glycopeptides 129-142 desmocollin 2 Homo sapiens 162-166 35371101-6 2022 In addition, Alum adjuvant and built-in TLR7a synergistically enhanced MUC1 glycopeptide-specific memory CD8+ T-cell immune responses. Glycopeptides 76-88 mucin 1, transmembrane Mus musculus 71-75 35364384-3 2022 The stability of the new glycopeptide derivatives 10a,b is confirmed by assessing the physical character, HOMO-LUMO gap energy, ESP, and the corresponding correlation of 2D-NMR analysis. Glycopeptides 25-37 protein tyrosine phosphatase receptor type V, pseudogene Homo sapiens 128-131 35415375-5 2022 As compared to the parental cells, cells with mutations in exon 9 (E545K) or exon 20 (H1047R) of the PIK3CA gene exhibited site-specific glycosylation alterations in 464 of the 1999 glycopeptides quantified. Glycopeptides 182-195 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens 101-107 35350332-9 2022 By cross-comparison with our previous urinary glycoproteomic dataset for aggressive prostate cancer, we reported a total of four glycopeptides from glycoproteins DSC2, MGAM, PIK3IP1, and CD55, commonly identified to be prostate cancer-specific. Glycopeptides 129-142 maltase-glucoamylase Homo sapiens 168-172 35350332-9 2022 By cross-comparison with our previous urinary glycoproteomic dataset for aggressive prostate cancer, we reported a total of four glycopeptides from glycoproteins DSC2, MGAM, PIK3IP1, and CD55, commonly identified to be prostate cancer-specific. Glycopeptides 129-142 phosphoinositide-3-kinase interacting protein 1 Homo sapiens 174-181 35350332-9 2022 By cross-comparison with our previous urinary glycoproteomic dataset for aggressive prostate cancer, we reported a total of four glycopeptides from glycoproteins DSC2, MGAM, PIK3IP1, and CD55, commonly identified to be prostate cancer-specific. Glycopeptides 129-142 CD55 molecule (Cromer blood group) Homo sapiens 187-191 34991034-2 2022 Here, a co-assembled glycopeptide nanotransforrs (GPNTs) named MRP@DOX as a drug delivery system is reported. Glycopeptides 21-33 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 63-66 35122907-7 2022 CONCLUSIONS: A glycopeptide based diagnostic tool would be beneficial for patient stratification by providing information about the functionality of HNF1A. Glycopeptides 15-27 HNF1 homeobox A Homo sapiens 149-154 34991034-3 2022 The MRP@DOX co-assemble nanoparticles consisting of glycopeptide, cationic peptide, and doxorubicin (DOX). Glycopeptides 52-64 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus 4-7 35186526-2 2022 They are Gram-positive, catalase-negative cocci that are intrinsically resistant to glycopeptides, including vancomycin. Glycopeptides 84-97 catalase Homo sapiens 24-32