PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 6321048-0 1984 Quantitative significance of glutathione and glutathione-S-transferase in regulating benzo[a]pyrene anti diol-epoxide level in reconstituted C3H/10T1/2 cell lysates, and comparison to rat liver. benzo[a] 85-93 hematopoietic prostaglandin D synthase Mus musculus 45-70 2799823-1 1989 m-Xylene (1 g/kg, i.p., 1 h) was shown to decrease aryl hydrocarbon hydroxylase (AHH) activity, a detoxification pathway for benzo[a]pyrene (BaP), in the rat lung. benzo[a] 125-133 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 51-79 2799823-1 1989 m-Xylene (1 g/kg, i.p., 1 h) was shown to decrease aryl hydrocarbon hydroxylase (AHH) activity, a detoxification pathway for benzo[a]pyrene (BaP), in the rat lung. benzo[a] 125-133 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 81-84 28522830-7 2017 Imaging flow cytometry also showed that CD1a and CD1d proteins were retained in early and late endosomal compartments, respectively, supporting an impaired endocytic lipid antigen presentation for T cell activation upon benzo[a]pyrene exposure. benzo[a] 220-228 CD1a molecule Homo sapiens 40-44 28412278-0 2017 Disruption of glutamate neurotransmitter transmission is modulated by SNAP-25 in benzo[a]pyrene-induced neurotoxic effects. benzo[a] 81-89 synaptosome associated protein 25 Homo sapiens 70-77 28522830-7 2017 Imaging flow cytometry also showed that CD1a and CD1d proteins were retained in early and late endosomal compartments, respectively, supporting an impaired endocytic lipid antigen presentation for T cell activation upon benzo[a]pyrene exposure. benzo[a] 220-228 CD1d molecule Homo sapiens 49-53 25854346-6 2015 RESULTS: Findings revealed that PEITC inhibited benzo[a]pyrene-induced rise in rat liver CYP1A1 mRNA in a dose-dependent manner as well as the apoprotein levels of CYP1A. benzo[a] 48-56 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 89-95 28187856-0 2017 Corrigendum to "PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a" [Chem. benzo[a] 58-66 tumor protein p53 Homo sapiens 81-84 28187856-0 2017 Corrigendum to "PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a" [Chem. benzo[a] 58-66 forkhead box O3 Homo sapiens 98-104 20840854-0 2010 Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis. benzo[a] 35-43 tumor protein p53 Homo sapiens 58-61 23052197-3 2013 Recently, the differential gene expression response in wild-type and cancer-prone Xpa (-/-) p53 (+/-) primary mouse hepatocytes after exposure to benzo[a]pyrene (B[a]P) revealed downregulation of cancer-related pathways in Xpa (-/-) p53 (+/-) hepatocytes only. benzo[a] 194-202 xeroderma pigmentosum, complementation group A Mus musculus 82-85 23052197-3 2013 Recently, the differential gene expression response in wild-type and cancer-prone Xpa (-/-) p53 (+/-) primary mouse hepatocytes after exposure to benzo[a]pyrene (B[a]P) revealed downregulation of cancer-related pathways in Xpa (-/-) p53 (+/-) hepatocytes only. benzo[a] 194-202 transformation related protein 53, pseudogene Mus musculus 124-127 23052197-3 2013 Recently, the differential gene expression response in wild-type and cancer-prone Xpa (-/-) p53 (+/-) primary mouse hepatocytes after exposure to benzo[a]pyrene (B[a]P) revealed downregulation of cancer-related pathways in Xpa (-/-) p53 (+/-) hepatocytes only. benzo[a] 194-202 xeroderma pigmentosum, complementation group A Mus musculus 271-274 23052197-3 2013 Recently, the differential gene expression response in wild-type and cancer-prone Xpa (-/-) p53 (+/-) primary mouse hepatocytes after exposure to benzo[a]pyrene (B[a]P) revealed downregulation of cancer-related pathways in Xpa (-/-) p53 (+/-) hepatocytes only. benzo[a] 194-202 transformation related protein 53, pseudogene Mus musculus 313-316 17237483-0 2007 Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation. benzo[a] 40-48 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 63-69 18430445-0 2008 Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo[a]pyrene-exposed human lung cancer cells. benzo[a] 89-97 RAD51 recombinase Homo sapiens 13-18 18430445-0 2008 Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo[a]pyrene-exposed human lung cancer cells. benzo[a] 89-97 mitogen-activated protein kinase 14 Homo sapiens 37-40 18855977-0 2008 Depletion of CD4(+)CD25(+) regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma. benzo[a] 101-109 CD4 antigen Mus musculus 13-16 1335374-5 1992 Only those congeners which bound to the aryl hydrocarbon (Ah) receptor, namely benzo[a]pyrene, benz[a]anthracene, 7,12-dimethylbenz[a]anthracene and MC, caused a decrease in nuclear ER levels. benzo[a] 79-87 aryl hydrocarbon receptor Homo sapiens 40-70 16377763-2 2006 Paradoxically, however, Cyp1a1-/- knockout mice are more sensitive to oral benzo[a]pyrene exposure, compared with wild-type Cyp1a1+/+ mice (Mol Pharmacol 65:1225, 2004). benzo[a] 75-83 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 24-30 7516235-3 1994 This latter nucleotide change results in an altered amino acid (462Ile-->Val), which is purported to increase CYP1A1 enzyme activity and mutagenicity towards benzo[a]pyrene about two-fold among Japanese. benzo[a] 161-169 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 113-119 17029827-3 2006 The p53 protein activation appeared to have been a downstream response to the benzo[a]pyrene-induced DNA damage, suggesting p53 plays important roles in the defense against benzo[a]pyrene-induced genotoxicity. benzo[a] 78-86 tumor protein p53 Homo sapiens 4-7 17029827-3 2006 The p53 protein activation appeared to have been a downstream response to the benzo[a]pyrene-induced DNA damage, suggesting p53 plays important roles in the defense against benzo[a]pyrene-induced genotoxicity. benzo[a] 78-86 tumor protein p53 Homo sapiens 124-127 16433037-4 2006 The results allowed us to draw preliminary conclusions about the structural features of benzo[a]phenoxazines which are important for MDR modulation. benzo[a] 88-96 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 133-136 8847147-3 1995 In uncrowded (Td, 18 hr) and crowded (Td, 32 hr) cultures of benzo[a]pyrene-transformed cells intracellular CD levels were one third and two thirds, respectively, of those measured in hyperconfluent 3T3 cultures. benzo[a] 61-69 cathepsin D Mus musculus 108-110 20693099-1 1994 Cytotoxicity and mutagenicity were measured in human lymphocytes after treatment in vitro with anti- or syn-benzo[a]pyrene diolepoxide, two diastereoisomer metabolites of benzo[a]pyrene. benzo[a] 108-116 synemin Homo sapiens 104-107