PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
24750035-6	2015	Androgen agonist mesterolone also increased H2S and induced vasodilatation; effects attenuated by the selective cystathionine-gamma lyase (CSE) inhibitor propargylglycine.	Mesterolone	17-28	cystathionine gamma-lyase	Homo sapiens	112-137
24750035-6	2015	Androgen agonist mesterolone also increased H2S and induced vasodilatation; effects attenuated by the selective cystathionine-gamma lyase (CSE) inhibitor propargylglycine.	Mesterolone	17-28	cystathionine gamma-lyase	Homo sapiens	139-142
6539197-3	1984	1 alpha-Methyl-5 alpha-dihydrotestosterone (1 alpha-methyl-DHT; mesterolone) bound most avidly to sex hormone-binding globulin (SHBG) [relative binding affinity (RBA) about 4 times that of DHT].	Mesterolone	64-75	sex hormone binding globulin	Rattus norvegicus	98-126
6539197-3	1984	1 alpha-Methyl-5 alpha-dihydrotestosterone (1 alpha-methyl-DHT; mesterolone) bound most avidly to sex hormone-binding globulin (SHBG) [relative binding affinity (RBA) about 4 times that of DHT].	Mesterolone	64-75	sex hormone binding globulin	Rattus norvegicus	128-132
31884045-6	2020	Mesterolone, mestanolone and methenolone increased mineralocorticoid but decreased adrenal androgen production, indicating CYP17A1 dysfunction.	Mesterolone	0-11	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	123-130
822257-0	1976	[Effect of mesterolone on the erythropoietin activity and hematocrit in long-term hemodialysis patients].	Mesterolone	11-22	erythropoietin	Homo sapiens	30-44
776594-4	1976	Basal levels of LH and FSH discharge were not influenced by mesterolone, whereas inhibition of LH-RH stimulated gonadotropin release was noted at 25 mug mesterolone/ml medium.	Mesterolone	153-164	gonadotropin releasing hormone 1	Homo sapiens	95-100
22419647-11	2012	In addition, greater DNA concentration and Pax7 protein expression were found in mesterolone-treated birds.	Mesterolone	81-92	paired box 7	Gallus gallus	43-47
29058169-7	2017	MEST treatment increased markedly LDL levels (40%) in sedentary CETP/R1 mice and reduced HDL levels in exercised R1 mice (18%).	Mesterolone	0-4	cholesteryl ester transfer protein	Homo sapiens	64-68
23018244-7	2012	Mesterolone administered to sedentary mice (Sed-C x Sed-M) significantly upregulated NOS I in TA and SOL and NOS III in all three muscles.	Mesterolone	0-11	nitric oxide synthase 3, endothelial cell	Mus musculus	109-116
23018244-8	2012	Mesterolone administered to exercised mice (Ex-C x Ex-M) upregulated NOS I in all three muscles and NOS III in TA and SOL.	Mesterolone	0-11	nitric oxide synthase 1, neuronal	Mus musculus	69-74
23018244-9	2012	The exercise to mesterolone-treated mice (Sed-M x Ex-M) produced a strong increase in NOS I expression in GAS; in contrast it antagonized the mesterolone-induced upregulation of NOS I in TA muscle and NOS III in SOL and GAS.	Mesterolone	16-27	nitric oxide synthase 1, neuronal	Mus musculus	86-91
24260508-12	2013	In the SOL, mesterolone treatment (Sed-M and ex-M) caused dramatic increases in the percentages of fiber types IC, IIAC, IIAD, IID, with concomitant decrease in IIA, but had minimal impact on fiber type percentages in the predominantly fast muscles.	Mesterolone	12-23	myosin, heavy polypeptide 1, skeletal muscle, adult	Mus musculus	127-130
24260508-12	2013	In the SOL, mesterolone treatment (Sed-M and ex-M) caused dramatic increases in the percentages of fiber types IC, IIAC, IIAD, IID, with concomitant decrease in IIA, but had minimal impact on fiber type percentages in the predominantly fast muscles.	Mesterolone	12-23	ATPase, class II, type 9A	Mus musculus	115-118
10935543-8	2000	Strikingly, the transactivation defect of the mutant AR can be rectified in vitro with mesterolone, consistent with the ability of this androgen analog to restore sperm production in vivo.	Mesterolone	87-98	androgen receptor	Homo sapiens	53-55
18808528-7	2008	Treatment with mesterolone increased total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-c) and very LDL-c (VLDL-c) plasma levels.	Mesterolone	15-26	component of oligomeric golgi complex 2	Mus musculus	70-105
18808528-7	2008	Treatment with mesterolone increased total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-c) and very LDL-c (VLDL-c) plasma levels.	Mesterolone	15-26	component of oligomeric golgi complex 2	Mus musculus	107-112
18808528-7	2008	Treatment with mesterolone increased total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-c) and very LDL-c (VLDL-c) plasma levels.	Mesterolone	15-26	component of oligomeric golgi complex 2	Mus musculus	123-128
10935543-9	2000	Mesterolone, but not the physiological androgen dihydrotestosterone, restored mutant LBD interactions with the TAD and with TIF2, when expressed as fusion proteins in the two-hybrid assay.	Mesterolone	0-11	nuclear receptor coactivator 2	Homo sapiens	124-128