PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
10409658-6	1999	Co expression of minK and KvLQT1 channel subunits induces a slow delayed rectifier K(+) current, I(Ks), characterized by slow activation and a markedly increased magnitude compared with current induced by KvLQT1 subunits alone.	Potassium	99-101	ADP ribosylation factor GTPase activating protein 1 S homeolog	Xenopus laevis	26-32
10409658-8	1999	The decrease in I(Ks) caused by loss of function or altered gating properties explains the prolonged QT interval and increased risk of arrhythmia and sudden death associated with these mutations in KVLQT1.	Potassium	18-20	ADP ribosylation factor GTPase activating protein 1 S homeolog	Xenopus laevis	198-204
10381588-0	1999	The erg-like potassium current in rat lactotrophs.	Potassium	13-22	ETS transcription factor ERG	Rattus norvegicus	4-7
10402472-6	1999	The endocytosis and recycling of E-cadherin and of the transferrin receptor were similarly inhibited by potassium depletion and by bafilomycin treatment, and both proteins were accumulated in intracellular compartments by an 18 degrees C temperature block, suggesting that endocytosis may occur via a clathrin-mediated pathway.	Potassium	104-113	cadherin 1	Homo sapiens	33-43
10408765-9	1999	These findings suggest that hyperinsulinemia and insulin-induced transmembrane shift of extracellular potassium and phosphate may have been involved in the abnormalities of serum electrolytes and development of hypokalemic periodic paralysis in the present patient.	Potassium	102-111	insulin	Homo sapiens	33-40
10430112-8	1999	CONCLUSION: In salt-depleted subjects, selective inhibition of COX-2 causes sodium and potassium retention.	Potassium	87-96	prostaglandin-endoperoxide synthase 2	Homo sapiens	63-68
10501019-9	1999	Moreover, arachidonyltrifluoromethyl ketone (AACOCF3) and quinacrine (QUIN), both phospholipase A2 (PLA2) inhibitors, markedly decreased enhanced [3H]choline transport and [3H]HC-3 binding induced by antecedent exposure to depolarizing concentrations of potassium.	Potassium	254-263	phospholipase A2 group IB	Homo sapiens	100-104
10377339-6	1999	Only rostral hair cells exhibited an inactivating potassium current (IA), whereas an inwardly rectifying potassium current (IK1) was identified only in caudal AP hair cells.	Potassium	105-114	IKAROS family zinc finger 1	Homo sapiens	124-127
10349593-2	1999	With potassium replacement, high CPK blood level and myopathic signs returned to normal.	Potassium	5-14	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	33-36
10385697-11	1999	Elevated potassium stimulation of GAL mRNA was completely blocked, but pituitary adenylyl cyclase-activating polypeptide and histamine stimulations were only partially blocked, by cycloheximide.	Potassium	9-18	galanin and GMAP prepropeptide	Homo sapiens	34-37
10395328-2	1999	Here we demonstrate that AIDS-KS cells express surface interleukin-4 (IL-4) receptors, and that IL-4 toxin (IL-4(38-37)-PE38KDEL) is specifically cytotoxic to these cells.	Potassium	30-32	interleukin 4	Mus musculus	55-68
10395328-2	1999	Here we demonstrate that AIDS-KS cells express surface interleukin-4 (IL-4) receptors, and that IL-4 toxin (IL-4(38-37)-PE38KDEL) is specifically cytotoxic to these cells.	Potassium	30-32	interleukin 4	Mus musculus	70-74
10444309-15	1999	NPY significantly stimulated SS and inhibited basal and potassium-stimulated GHRH release, while potentiating potassium-evoked AVP secretion.	Potassium	56-65	neuropeptide Y	Rattus norvegicus	0-3
10444309-15	1999	NPY significantly stimulated SS and inhibited basal and potassium-stimulated GHRH release, while potentiating potassium-evoked AVP secretion.	Potassium	56-65	growth hormone releasing hormone	Rattus norvegicus	77-81
10444309-15	1999	NPY significantly stimulated SS and inhibited basal and potassium-stimulated GHRH release, while potentiating potassium-evoked AVP secretion.	Potassium	110-119	neuropeptide Y	Rattus norvegicus	0-3
10369308-2	1999	To date, 18 missense mutations in the adult skeletal muscle sodium channel alpha-subunit (SCN4A) gene have been identified to cause a spectrum of muscular diseases, including PMC of von Eulenburg, PMC without cold paralysis, potassium-aggravating myotonia, and hyperkalemic periodic paralysis.	Potassium	225-234	sodium voltage-gated channel alpha subunit 4	Homo sapiens	44-88
10366610-1	1999	Hyperkalaemic periodic paralysis, paramyotonia congenita, and potassium-aggravated myotonia are three autosomal dominant skeletal muscle disorders linked to the SCN4A gene encoding the alpha-subunit of the human voltage-sensitive sodium channel.	Potassium	62-71	sodium voltage-gated channel alpha subunit 4	Homo sapiens	161-166
10369308-2	1999	To date, 18 missense mutations in the adult skeletal muscle sodium channel alpha-subunit (SCN4A) gene have been identified to cause a spectrum of muscular diseases, including PMC of von Eulenburg, PMC without cold paralysis, potassium-aggravating myotonia, and hyperkalemic periodic paralysis.	Potassium	225-234	sodium voltage-gated channel alpha subunit 4	Homo sapiens	90-95
10376919-9	1999	CONCLUSIONS: LQT1-associated mutations in KVLQT1 caused a spectrum of dysfunction in I(Ks) and KvLQT1 channels.	Potassium	87-89	ADP ribosylation factor GTPase activating protein 1 L homeolog	Xenopus laevis	13-17
10336628-26	1999	The Ks of plant CYP51 for LAB170250F (0.29 microM) and gamma-ketotriazole (0.40 microM) calculated from the type-II sp2 nitrogen-binding spectra were in better agreement with their reported effects as plant CYP51 inhibitors than values previously determined with plant microsomes.	Potassium	4-6	sterol 14-demethylase	Saccharomyces cerevisiae S288C	16-21
10336628-26	1999	The Ks of plant CYP51 for LAB170250F (0.29 microM) and gamma-ketotriazole (0.40 microM) calculated from the type-II sp2 nitrogen-binding spectra were in better agreement with their reported effects as plant CYP51 inhibitors than values previously determined with plant microsomes.	Potassium	4-6	sterol 14-demethylase	Saccharomyces cerevisiae S288C	207-212
10352033-0	1999	Potassium-dependent changes in the conformation of the Kv2.1 potassium channel pore.	Potassium	0-9	potassium voltage-gated channel subfamily B member 1	Homo sapiens	55-60
10411997-4	1999	The estimated reversal potential of this T-588 effect was near -90 mV which is the reversal potential of potassium ions in CA1 neurons.	Potassium	105-114	carbonic anhydrase 1	Rattus norvegicus	123-126
10411997-5	1999	In the whole-cell voltage-clamp study, T-588 produced a reversible block of the outward potassium current in CA1 neurons.	Potassium	88-97	carbonic anhydrase 1	Rattus norvegicus	109-112
10411997-7	1999	These results suggest that T-588 has a direct effect on CA1 neurons independent of its cholinergic activity, resulting from blockade of a conductance carried predominantly by potassium ions.	Potassium	175-184	carbonic anhydrase 1	Rattus norvegicus	56-59
10376919-9	1999	CONCLUSIONS: LQT1-associated mutations in KVLQT1 caused a spectrum of dysfunction in I(Ks) and KvLQT1 channels.	Potassium	87-89	ADP ribosylation factor GTPase activating protein 1 L homeolog	Xenopus laevis	42-48
10382996-5	1999	RESULTS: A single systemic injection of Ad.RSV-ANP at a dose of 1.2x10(10) pfu results in a significant increase in urine excretion, water intake, urinary sodium and potassium excretion.	Potassium	166-175	natriuretic peptide A	Rattus norvegicus	47-50
10406005-2	1999	That aberrant potassium (K+) channel function occurs in AD patients is supported by deleterious effects of A beta on normal fibroblast K+ channels and prevention of A beta-induced toxicity by potassium channel openers (KCOs) in neuronal cell culture.	Potassium	14-23	amyloid beta precursor protein	Homo sapiens	107-113
10359214-5	1999	The expression of CD80 in KS cells was required for an effective activation and expansion of Ag-specific T cells.	Potassium	26-28	CD80 molecule	Homo sapiens	18-22
10406005-2	1999	That aberrant potassium (K+) channel function occurs in AD patients is supported by deleterious effects of A beta on normal fibroblast K+ channels and prevention of A beta-induced toxicity by potassium channel openers (KCOs) in neuronal cell culture.	Potassium	14-23	amyloid beta precursor protein	Homo sapiens	165-171
10320357-1	1999	cDNAs of human and bovine retinal rod Na+-Ca2++K+ exchanger (NCKX1) have previously been cloned, but potassium-dependent Na-Ca exchange activity upon heterologous expression has not been demonstrated.	Potassium	101-110	solute carrier family 24 member 1	Homo sapiens	61-66
10405886-2	1999	Indeed, the initial success of systemic IFN-alpha treatment in AIDS-associated Kaposi"s sarcoma (AIDS-KS) occurred before identification of the human immunodeficiency virus (HIV) and in the absence of any coherent view of KS pathogenesis.	Potassium	102-104	interferon alpha 1	Homo sapiens	40-43
10405886-3	1999	With a more comprehensive understanding how KS develops and which circumstances provide an increased virulence of this neoplasm in HIV-infected persons, a more subtle rationale for IFN-alpha treatment arose regarding the disorder of the endogenous IFN-system in HIV-positive individuals.	Potassium	44-46	interferon alpha 1	Homo sapiens	181-190
10405886-3	1999	With a more comprehensive understanding how KS develops and which circumstances provide an increased virulence of this neoplasm in HIV-infected persons, a more subtle rationale for IFN-alpha treatment arose regarding the disorder of the endogenous IFN-system in HIV-positive individuals.	Potassium	44-46	interferon alpha 1	Homo sapiens	181-184
10405886-17	1999	The consequences for treatment options with IFN are a combination with ribavirin in CHC and a graduated systemic treatment schedule in AIDS-KS starting with IFN-treatment in early disease followed by chemotherapy in advanced stages of KS.	Potassium	140-142	interferon alpha 1	Homo sapiens	44-47
10383119-5	1999	[(1996) Mol Cell Neurosci 7:222-238] reported that the high potassium-mediated secretion of brain-derived neurotrophic factor (BDNF) from hippocampal cultures was dependent on extracellular calcium.	Potassium	60-69	brain derived neurotrophic factor	Homo sapiens	92-125
10383119-5	1999	[(1996) Mol Cell Neurosci 7:222-238] reported that the high potassium-mediated secretion of brain-derived neurotrophic factor (BDNF) from hippocampal cultures was dependent on extracellular calcium.	Potassium	60-69	brain derived neurotrophic factor	Homo sapiens	127-131
10207057-5	1999	These phenotypic effects of the mutations correlate with changes in cation uptake and are dependent on a functional Trk1-Trk2 potassium transport system.	Potassium	126-135	Trk1p	Saccharomyces cerevisiae S288C	116-120
10213799-6	1999	Discussed are recent advances in the areas of: 1) g-aminobutyric acid subtype A receptor/benzodiazepine (GABAA/BZ) inverse agonists; 2) nicotinic acetylcholine receptor (nAChR) agonists; 3) serotonin subtype 3 receptor (5-HT3R) antagonists; and 4) potassium (K+) M-channel inhibitors.	Potassium	248-257	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	170-175
10207057-7	1999	These results suggest that the Hal4 and Hal5 protein kinases activate the Trk1-Trk2 potassium transporter, increasing the influx of potassium and decreasing the membrane potential.	Potassium	84-93	Trk2p	Saccharomyces cerevisiae S288C	79-83
10436405-9	1999	EGF also decreased net potassium secretion from -27.7+/-5.9 to -7.8+/-1.5 pmol/mm/min (n = 6, p<0.01).	Potassium	23-32	pro-epidermal growth factor	Oryctolagus cuniculus	0-3
10207057-5	1999	These phenotypic effects of the mutations correlate with changes in cation uptake and are dependent on a functional Trk1-Trk2 potassium transport system.	Potassium	126-135	Trk2p	Saccharomyces cerevisiae S288C	121-125
10436405-13	1999	In conclusion, EGF depolarizes transepithelial voltage by inhibiting sodium transport primarily and potassium and chloride transport secondarily.	Potassium	100-109	pro-epidermal growth factor	Oryctolagus cuniculus	15-18
10207057-6	1999	In addition, hal4 hal5 and trk1 trk2 mutants exhibit similar phenotypes: (i) they are deficient in potassium uptake; (ii) their growth is sensitive to a variety of toxic cations, including lithium, sodium, calcium, tetramethylammonium, hygromycin B, and low pH; and (iii) they exhibit increased uptake of methylammonium, an indicator of membrane potential.	Potassium	99-108	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	13-17
10207057-7	1999	These results suggest that the Hal4 and Hal5 protein kinases activate the Trk1-Trk2 potassium transporter, increasing the influx of potassium and decreasing the membrane potential.	Potassium	84-93	Trk1p	Saccharomyces cerevisiae S288C	74-78
10207057-6	1999	In addition, hal4 hal5 and trk1 trk2 mutants exhibit similar phenotypes: (i) they are deficient in potassium uptake; (ii) their growth is sensitive to a variety of toxic cations, including lithium, sodium, calcium, tetramethylammonium, hygromycin B, and low pH; and (iii) they exhibit increased uptake of methylammonium, an indicator of membrane potential.	Potassium	99-108	protein kinase HAL5	Saccharomyces cerevisiae S288C	18-22
10207057-6	1999	In addition, hal4 hal5 and trk1 trk2 mutants exhibit similar phenotypes: (i) they are deficient in potassium uptake; (ii) their growth is sensitive to a variety of toxic cations, including lithium, sodium, calcium, tetramethylammonium, hygromycin B, and low pH; and (iii) they exhibit increased uptake of methylammonium, an indicator of membrane potential.	Potassium	99-108	Trk1p	Saccharomyces cerevisiae S288C	27-31
10207057-6	1999	In addition, hal4 hal5 and trk1 trk2 mutants exhibit similar phenotypes: (i) they are deficient in potassium uptake; (ii) their growth is sensitive to a variety of toxic cations, including lithium, sodium, calcium, tetramethylammonium, hygromycin B, and low pH; and (iii) they exhibit increased uptake of methylammonium, an indicator of membrane potential.	Potassium	99-108	Trk2p	Saccharomyces cerevisiae S288C	32-36
10207057-7	1999	These results suggest that the Hal4 and Hal5 protein kinases activate the Trk1-Trk2 potassium transporter, increasing the influx of potassium and decreasing the membrane potential.	Potassium	84-93	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	31-35
10207057-7	1999	These results suggest that the Hal4 and Hal5 protein kinases activate the Trk1-Trk2 potassium transporter, increasing the influx of potassium and decreasing the membrane potential.	Potassium	84-93	protein kinase HAL5	Saccharomyces cerevisiae S288C	40-44
10414310-2	1999	HERG encodes the Kr channel, and KVLQT1 and hminK encode subunits that coassemble to form Ks channels.	Potassium	90-92	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	33-39
10087024-0	1999	Precontraction with elevated concentrations of extracellular potassium enables both 5-HT1B and 5-HT2A "silent" receptors in rabbit ear artery.	Potassium	61-70	5-hydroxytryptamine receptor 1B	Oryctolagus cuniculus	84-90
10206953-2	1999	Here we report that the mutation of these residues in Kv1.1 to leucine, proline, or arginine abolished the expression of outward potassium currents in Xenopus oocytes.	Potassium	129-138	potassium channel, voltage gated shaker related subfamily A, member 1 S homeolog	Xenopus laevis	54-59
10218673-5	1999	P53 and Ki-67 immunoreactivity correlated significantly with the histopathologic stage of KS (r=0.63, p=0.0001; r=0.42, p=0.0084, respectively).	Potassium	90-92	tumor protein p53	Homo sapiens	0-3
10218673-10	1999	The expression of p53 and Ki-67 was significantly lower in iatrogenic cases than in the classic cases (p=0.009, p=0.0014, respectively), although no statistical difference was found between the histopathologic stages in the two clinical forms of KS.	Potassium	246-248	tumor protein p53	Homo sapiens	18-21
10098511-8	1999	The Ca2+-mobilizing agonist, potassium (K+; 4 mmol/liter), greatly increased the hCG responses of StAR expression and P production, which conversely were attenuated by Ca2+ antagonists, further supporting the involvement of intracellular free Ca2+ ([Ca2+]i) in these responses.	Potassium	29-38	hypertrichosis 2 (generalised, congenital)	Homo sapiens	81-84
10098511-8	1999	The Ca2+-mobilizing agonist, potassium (K+; 4 mmol/liter), greatly increased the hCG responses of StAR expression and P production, which conversely were attenuated by Ca2+ antagonists, further supporting the involvement of intracellular free Ca2+ ([Ca2+]i) in these responses.	Potassium	29-38	steroidogenic acute regulatory protein	Mus musculus	98-102
10339950-5	1999	In addition, attention should be paid to factors causing an additional reduction in the serum potassium concentration, such as alkalosis, elevated beta 2-adrenergic activity, increased availability of insulin and hypothermia.	Potassium	94-103	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	147-153
10207802-9	1999	In 7-day old hepatic stellate cells, after stimulation of cell transformation with TGF-beta-1, an enhanced [Ca2+]i response to potassium elevation was detected, while inhibition of transformation with IFN-gamma for the same time caused a decreased calcium signal compared with untreated control cultures.	Potassium	127-136	transforming growth factor, beta 1	Rattus norvegicus	83-93
10077678-4	1999	Here we show that the K+ channel KAT1 expressed in Arabidopsis guard cells and yeast is capable of mediating potassium uptake from media containing as little as 10 microM of external K+.	Potassium	109-118	kynurenine aminotransferase 1	Homo sapiens	33-37
10052930-3	1999	We found that when choline or potassium were the major cations present, light caused a 70% inhibition of stimulated ROS-GC in native unstripped membranes.	Potassium	30-39	guanylate cyclase 2D, retinal	Bos taurus	116-122
10082974-0	1999	Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current.	Potassium	86-95	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	10-17
9952418-0	1999	GDNF protection against 6-OHDA-induced reductions in potassium-evoked overflow of striatal dopamine.	Potassium	53-62	glial cell derived neurotrophic factor	Rattus norvegicus	0-4
10070172-0	1999	Potassium supplement upregulates the expression of renal kallikrein and bradykinin B2 receptor in SHR.	Potassium	0-9	kallikrein 1	Rattus norvegicus	51-67
10070908-3	1999	We reasoned that the impact of ACE inhibitors on plasma potassium could be minimized by administering these agents at very low doses.	Potassium	56-65	angiotensin I converting enzyme	Homo sapiens	31-34
10102362-3	1999	Characterization of the potassium dependence of recombinants possessing two mutant trk alleles suggests that the protein products of TRK2 and TRK3 interact functionally, and that TRK1 may serve a regulatory function.	Potassium	24-33	uncharacterized protein	Chlamydomonas reinhardtii	179-183
9973509-3	1999	KS serum and IgG fraction each showed significant (88%) inhibition of asparaginyl-tRNA synthetase (AsnRS) activity, but not of any of the other 19 aminoacyl-tRNA synthetase activities.	Potassium	0-2	asparaginyl-tRNA synthetase 1	Homo sapiens	70-97
9973509-3	1999	KS serum and IgG fraction each showed significant (88%) inhibition of asparaginyl-tRNA synthetase (AsnRS) activity, but not of any of the other 19 aminoacyl-tRNA synthetase activities.	Potassium	0-2	asparaginyl-tRNA synthetase 1	Homo sapiens	99-104
10089235-0	1999	Potassium uptake through the TOK1 K+ channel in the budding yeast.	Potassium	0-9	Tok1p	Saccharomyces cerevisiae S288C	29-33
10202384-9	1999	Capsaicin at 10-6 mol L-1 and potassium at 70 mmol L-1 induced a profound increase in airway tone (50 +/- 9 and 42 +/- 8 cmH2O mL-1 min respectively; P < 0.01) and elevation of both CGRP (6.4 +/- 1.9 and 3.9 +/- 1.1 fmol mL-1 g respectively; P < 0.05) and NKA (3.3 +/- 1.0 and 1.0 +/- 0.2 fmol mL-1 respectively; P < 0.05).	Potassium	30-39	L1 cell adhesion molecule	Mus musculus	51-54
10202384-9	1999	Capsaicin at 10-6 mol L-1 and potassium at 70 mmol L-1 induced a profound increase in airway tone (50 +/- 9 and 42 +/- 8 cmH2O mL-1 min respectively; P < 0.01) and elevation of both CGRP (6.4 +/- 1.9 and 3.9 +/- 1.1 fmol mL-1 g respectively; P < 0.05) and NKA (3.3 +/- 1.0 and 1.0 +/- 0.2 fmol mL-1 respectively; P < 0.05).	Potassium	30-39	L1 cell adhesion molecule	Mus musculus	127-131
10202384-9	1999	Capsaicin at 10-6 mol L-1 and potassium at 70 mmol L-1 induced a profound increase in airway tone (50 +/- 9 and 42 +/- 8 cmH2O mL-1 min respectively; P < 0.01) and elevation of both CGRP (6.4 +/- 1.9 and 3.9 +/- 1.1 fmol mL-1 g respectively; P < 0.05) and NKA (3.3 +/- 1.0 and 1.0 +/- 0.2 fmol mL-1 respectively; P < 0.05).	Potassium	30-39	L1 cell adhesion molecule	Mus musculus	224-228
10202384-9	1999	Capsaicin at 10-6 mol L-1 and potassium at 70 mmol L-1 induced a profound increase in airway tone (50 +/- 9 and 42 +/- 8 cmH2O mL-1 min respectively; P < 0.01) and elevation of both CGRP (6.4 +/- 1.9 and 3.9 +/- 1.1 fmol mL-1 g respectively; P < 0.05) and NKA (3.3 +/- 1.0 and 1.0 +/- 0.2 fmol mL-1 respectively; P < 0.05).	Potassium	30-39	L1 cell adhesion molecule	Mus musculus	224-228
10029533-8	1999	This suggests that K27 in IbTX interacts with a potassium binding site in the pore.	Potassium	48-57	keratin 27	Homo sapiens	19-22
11673956-1	1999	Potassium, rubidium, and cesium thiocarboxylates were found to be synthesized by the reaction of thiocarboxylic acid or its O-trimethylsilyl esters with KF, RbF, and CsF.	Potassium	0-9	colony stimulating factor 2	Homo sapiens	166-169
9878764-1	1999	Cerebellar granule neurons maintained in medium containing 26 mM potassium or in medium (5 mM potassium) with 50 ng/ml brain-derived neurotrophic factor (BDNF) undergo an apoptotic cell death when exposed to 10 microM LY294002, an inhibitor of phosphatidylinositol 3-kinase (PI3-K).	Potassium	94-103	brain derived neurotrophic factor	Homo sapiens	119-152
9878764-1	1999	Cerebellar granule neurons maintained in medium containing 26 mM potassium or in medium (5 mM potassium) with 50 ng/ml brain-derived neurotrophic factor (BDNF) undergo an apoptotic cell death when exposed to 10 microM LY294002, an inhibitor of phosphatidylinositol 3-kinase (PI3-K).	Potassium	94-103	brain derived neurotrophic factor	Homo sapiens	154-158
10025409-7	1999	It abolishes the potassium currents of wild-type KCNQ4 on which it exerts a strong dominant-negative effect.	Potassium	17-26	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	49-54
10093051-10	1999	Membrane depolarization by elevated extracellular potassium ([K+]o) also attenuated the suppression of ET-1 mRNA by flow at [K+]o = 70 mM and completely inhibited it at [K+]o = 135 mM.	Potassium	50-59	endothelin 1	Bos taurus	103-107
10028924-5	1999	This study was designed to investigate the effects of extracellular magnesium (Mg2+) on HERG potassium currents.	Potassium	93-102	potassium voltage-gated channel subfamily H member 2	Homo sapiens	88-92
10090227-0	1999	Long-term (subacute) potassium treatment in congenital HERG-related long QT syndrome (LQTS2).	Potassium	21-30	potassium voltage-gated channel subfamily H member 2	Homo sapiens	55-59
10051143-12	1999	It was concluded that phrixotoxins, are new and specific blockers of Kv4.3 and Kv4.2 potassium currents, and hence of I(to1) that will enable further studies of Kv4.2 and Kv4.3 channel and/or I(to1) expression.	Potassium	85-94	potassium voltage-gated channel, Shal-related family, member 2	Mus musculus	79-84
10328327-17	1999	In conclusion, after enalapril in a salt-depleted state, the functional expression of acute angiotensin II deprivation was partially masked by the activation of a homeostatic system responsible both for improvement in renal salt conservation and for facilitated cellular potassium uptake.	Potassium	271-280	angiotensinogen	Homo sapiens	92-106
11972176-0	1999	[Effects of glutamate on transient outward potassium current of dissociated hippocampal neurons in ca1 sector in rats].	Potassium	43-52	carbonic anhydrase 1	Rattus norvegicus	99-102
9918600-0	1999	Block of potassium currents in guinea pig ventricular myocytes and lengthening of cardiac repolarization in man by the histamine H1 receptor antagonist diphenhydramine.	Potassium	9-18	histamine receptor H1	Homo sapiens	119-140
9890937-2	1999	Depolarization with potassium, activation of glutamate receptors with glutamate, or direct stimulation of protein kinase C with a phorbol ester increased RC3 phosphorylation in wild-type animals but failed to affect RC3 phosphorylation in mice lacking the gamma-subtype of protein kinase C. Our results suggests the following biochemical pathway: activation of a postsynaptic (metabotropic) glutamate receptor stimulates the gamma-subtype of protein kinase C, which in turn phosphorylates RC3.	Potassium	20-29	neurogranin	Mus musculus	154-157
10635373-2	1999	We used our human head injury data base to determine relationships between potassium, glutamate, lactate and cerebral blood flow (CBF).	Potassium	75-84	CCAAT/enhancer binding protein zeta	Rattus norvegicus	130-133
10635373-6	1999	rCBF was negatively correlated with potassium with marginal significance (r = -0.35, p = 0.08).	Potassium	36-45	CCAAT/enhancer binding protein zeta	Rattus norvegicus	0-4
10635373-8	1999	These results in severely head injured patients confirm previous in vitro and animal studies in which relationships between potassium, glutamate, lactate and CBF were found.	Potassium	124-133	CCAAT/enhancer binding protein zeta	Rattus norvegicus	158-161
10330584-2	1999	The computation shows that practically all background neurone permeability for potassium ions is cAMP-dependent.	Potassium	79-88	cathelicidin antimicrobial peptide	Homo sapiens	97-101
10482044-3	1999	We investigated whether supplementation of potassium during euglycaemic glucose clamps influences insulin sensitivity.	Potassium	43-52	insulin	Homo sapiens	98-105
10325966-1	1999	OBJECTIVE: The Shal (or Kv4) gene family has been proposed to be responsible for primary subunits of the transient outward potassium current (Ito).	Potassium	123-132	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	24-27
10325966-6	1999	RESULTS: The transfection of HEK293 cells with rat Kv4.3 resulted in the expression of a time- and voltage-dependent outward potassium current.	Potassium	125-134	potassium voltage-gated channel subfamily D member 3	Rattus norvegicus	51-56
10482044-10	1999	In conclusion, this study shows that potassium supply during hyperinsulinaemic euglycaemic glucose clamps in healthy subjects does not influence the insulin sensitivity index.	Potassium	37-46	insulin	Homo sapiens	66-73
10027087-8	1999	In arteries the angiotensin II were subject to a mild degree of tachyphylaxis: the Emax of the repetitive concentration-response curve (CRC) was reduced from 105 +/- 4% of the potassium-induced contraction to 84 +/- 6% (P < 0.05); the EC50 value was unchanged (P > 0.05).	Potassium	176-185	angiotensinogen	Homo sapiens	16-30
10463998-8	1999	CONCLUSION: Our results suggest that the lower SPC activity in both nonproteinuric and proteinuric PIH may be an early sign of abnormality in the transport of sodium and potassium across the vascular smooth-muscle cell membrane, which is responsible for the maintenance of blood pressure.	Potassium	170-179	pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included)	Homo sapiens	99-102
10079511-11	1999	Our observations show that Shak-B(neural) is one of a set of embryonic gap-junction proteins, and that it is required for the normal temporal development of potassium currents in some larval muscles.	Potassium	157-166	shaking B	Drosophila melanogaster	27-33
9878074-1	1999	Previous patch-clamp studies have shown that the potassium permeability of the plasma membrane in HeLa cells, a cell line derived from an epidermoid carcinoma of the cervix, is controlled by various K+-selective pores including an IRK1 type inwardly rectifying K+ channel.	Potassium	49-58	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	231-235
9878133-2	1999	The elemental analyses of freshly cleaved mica surfaces by XPS showed that the potassium atoms on the surface lattice of mica are not necessarily distributed equally to each surface on cleavage.	Potassium	79-88	MHC class I polypeptide-related sequence A	Homo sapiens	42-46
9878133-2	1999	The elemental analyses of freshly cleaved mica surfaces by XPS showed that the potassium atoms on the surface lattice of mica are not necessarily distributed equally to each surface on cleavage.	Potassium	79-88	MHC class I polypeptide-related sequence A	Homo sapiens	121-125
9878133-3	1999	The adsorbed cationic amphiphile molecules remaining on mica surfaces after rinsing with distilled water were found to be anchored to the surface by ion-exchange, replacing surface potassium and/or other cations.	Potassium	181-190	MHC class I polypeptide-related sequence A	Homo sapiens	56-60
9878133-4	1999	The ratio of adsorbed cationic amphiphile molecules with single alkyl chains to the maximum potassium ions on mica surface was estimated to be twice as large as that of amphiphiles having two alkyl chains.	Potassium	92-101	MHC class I polypeptide-related sequence A	Homo sapiens	110-114
9886365-9	1999	Of particular interest, Ks-restricted virus-specific cytotoxicity-restricted CTLs were identified in the CNS of susceptible SJL/J (H-2s) and B10.S (H-2s) mice inoculated with DAL*-1.	Potassium	24-26	granzyme C	Mus musculus	141-144
9886365-9	1999	Of particular interest, Ks-restricted virus-specific cytotoxicity-restricted CTLs were identified in the CNS of susceptible SJL/J (H-2s) and B10.S (H-2s) mice inoculated with DAL*-1.	Potassium	24-26	erythrocyte membrane protein band 4.1 like 3	Mus musculus	175-181
9861043-0	1998	Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing.	Potassium	56-65	thyroid hormone receptor beta	Mus musculus	0-29
10391443-13	1999	Gp120 appears to activate astrocyte Na+/H+ exchangers to release glutamate and potassium and, subsequent to this, increases in [Ca2+]i in neurons and astrocytes result from activation of excitatory amino acid receptors on astrocytes and neurons, and voltage-operated calcium channels on neurons.	Potassium	79-88	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	0-5
9929573-1	1999	Functional and pharmacological data point to the involvement of KCNQ1/IsK potassium channels in the basolateral potassium conductance of secretory epithelia.	Potassium	74-83	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	64-69
9929573-1	1999	Functional and pharmacological data point to the involvement of KCNQ1/IsK potassium channels in the basolateral potassium conductance of secretory epithelia.	Potassium	74-83	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	70-73
9929573-7	1999	The low activation threshold at approximately -60 mV in combination with the high expression in rectal gland cells make s-KCNQ1 a potential candidate responsible for the basolateral potassium conductance.	Potassium	182-191	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	122-127
9877154-4	1998	This potassium current was increased following CGRP application or co-expression of CRLR, but decreased by PTX or co-expression of transducin.	Potassium	5-14	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	47-51
9824707-9	1998	RELK1 channels mediated slowly activating sustained potassium currents.	Potassium	52-61	potassium voltage-gated channel subfamily H member 4	Rattus norvegicus	0-5
9872395-1	1998	Human ATP1AL1 and corresponding genes of other mammals encode the catalytic alpha subunit of a non-gastric ouabain-sensitive H,K-ATPases, the ion pump presumably involved in maintenance of potassium homeostasis.	Potassium	189-198	ATPase H+/K+ transporting non-gastric alpha2 subunit	Homo sapiens	6-13
9852570-2	1998	Mutations in this channel cause hypokalemic periodic paralysis (HypoPP), a human autosomal dominant disorder characterized by episodic failure of muscle excitability that occurs in association with a decrease in serum potassium.	Potassium	218-227	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	64-70
9877154-4	1998	This potassium current was increased following CGRP application or co-expression of CRLR, but decreased by PTX or co-expression of transducin.	Potassium	5-14	calcitonin receptor-like	Mus musculus	84-88
9877154-4	1998	This potassium current was increased following CGRP application or co-expression of CRLR, but decreased by PTX or co-expression of transducin.	Potassium	5-14	guanine nucleotide binding protein, alpha transducing 1	Mus musculus	131-141
9834237-7	1998	Treatment of the APL-derived NB4 cells and the RA-resistant subclone NB4R4 with antimony trioxide or potassium antimonyl tartrat triggers the degradation of the fusion protein and the concomitant reorganization of the PML nuclear bodies.	Potassium	101-110	PML nuclear body scaffold	Homo sapiens	218-221
9843747-7	1998	We conclude that alteration of the transcellular potassium gradient may affect the regulation of the periovulatory surge of gonadotropins and progesterone secretion, probably by altering the release of GnRH from the hypothalamus.	Potassium	49-58	gonadotropin releasing hormone 1	Mus musculus	202-206
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	240-242	potassium voltage-gated channel modifier subfamily G member 1	Homo sapiens	49-52
9843594-2	1998	To examine the possible interrelationship between apical membrane H-K exchange and basolateral membrane K movement in rat distal colon in the regulation of pHi, experiments were designed to assess whether changes in extracellular potassium can alter pHi.	Potassium	230-239	glucose-6-phosphate isomerase	Rattus norvegicus	250-253
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	240-242	potassium voltage-gated channel modifier subfamily F member 1	Homo sapiens	85-88
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	63-65	potassium voltage-gated channel modifier subfamily F member 1	Homo sapiens	35-38
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	240-242	potassium voltage-gated channel modifier subfamily G member 1	Homo sapiens	93-96
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	63-65	potassium voltage-gated channel modifier subfamily G member 1	Homo sapiens	49-52
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	63-65	potassium voltage-gated channel modifier subfamily F member 1	Homo sapiens	85-88
9827540-4	1998	Two forms generate, after transient expression in COS cells, a potassium-selective current similar to the KCNQ1 current.	Potassium	63-72	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	106-111
10189269-3	1998	The pH-rate expression was k(pH) = kH1 f1(aH+) + kH2 f2(aH+) + ks + kOH(aOH-), where kH1 and kH2 are the catalytic constants (M(-1) h(-1)) for hydrogen ion activity (aH+), kOH is the catalytic constant for hydroxyl ion activity (aOH-), and ks is the first-order rate constant (h(-1)) for spontaneous degradation.	Potassium	63-65	potassium voltage-gated channel modifier subfamily G member 1	Homo sapiens	93-96
9831708-1	1998	ATP-sensitive potassium (KATP) channels in striated myocytes are heteromultimers of KIR6.2, a weak potassium inward rectifier, plus SUR2A, a low-affinity sulfonylurea receptor.	Potassium	14-23	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	84-90
9786983-1	1998	The Kv3.1 channel subunit, when expressed heterologously, gives rise to a high-threshold noninactivating potassium current.	Potassium	105-114	potassium voltage-gated channel subfamily C member 1	Homo sapiens	4-9
9786983-4	1998	Because spontaneous neuronal activity plays an important role in modulating neuronal excitability during development, we examined the effects of depolarization with an elevated concentration of external potassium ions on the expression of Kv3.1 channel subunits in immature inferior colliculus neurons.	Potassium	203-212	potassium voltage-gated channel subfamily C member 1	Homo sapiens	239-244
9755212-4	1998	Previous analysis of Igf2r, in the mouse-rat comparison, found Ka/Ks patterns that were suggested to be contrary to those expected under the conflict theory of imprinting.	Potassium	66-68	insulin-like growth factor 2 receptor	Mus musculus	21-26
9786983-5	1998	Elevated potassium produced a marked increase in Kv3.1 mRNA levels and in the amplitude of a high-threshold, noninactivating current before the onset of hearing.	Potassium	9-18	potassium voltage-gated channel subfamily C member 1	Homo sapiens	49-54
9763462-0	1998	Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors.	Potassium	51-60	carbonic anhydrase 3	Homo sapiens	96-99
9763462-1	1998	We characterized potassium current activated by G-protein-coupled receptors in acutely dissociated hippocampal CA3 neurons.	Potassium	17-26	carbonic anhydrase 3	Homo sapiens	111-114
9828151-7	1998	In the medium containing choline instead of sodium or the medium without potassium, an elevation of [Mg2+]i with addition of insulin/IGF-1 was moderately suppressed.	Potassium	73-82	insulin	Homo sapiens	125-132
9828151-7	1998	In the medium containing choline instead of sodium or the medium without potassium, an elevation of [Mg2+]i with addition of insulin/IGF-1 was moderately suppressed.	Potassium	73-82	insulin like growth factor 1	Homo sapiens	133-138
9819250-0	1998	Potassium conductance causing hyperpolarization of CA1 hippocampal neurons during hypoxia.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	51-54
9831261-7	1998	Experiments on c-fos gene expression in these cultures showed that while only 12% of the magnocellular OT and VP neurones contained barely detectable Fos protein in their nuclei under control conditions, potassium depolarization of these cultures for 3 h produced intense c-fos expression in 87-91% of these cells.	Potassium	204-213	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	272-277
9760292-0	1998	Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density.	Potassium	37-46	potassium voltage-gated channel subfamily D member 3	Homo sapiens	108-113
9893658-1	1998	S-1 is a novel oral anticancer drug, composed of tegafur (FT), gimestat (CDHP) and otastat potassium (Oxo) in a molar ratio of 1:0.4:1, based on the biochemical modulation of 5-fluorouracil (5-FU).	Potassium	91-100	proteasome 26S subunit, non-ATPase 1	Homo sapiens	0-3
9828151-9	1998	Insulin/ IGF-1 translocates Mg2+ from the extracellular space to intracellular space and these effects are affected by external sodium and potassium.	Potassium	139-148	insulin	Homo sapiens	0-7
9828151-9	1998	Insulin/ IGF-1 translocates Mg2+ from the extracellular space to intracellular space and these effects are affected by external sodium and potassium.	Potassium	139-148	insulin like growth factor 1	Homo sapiens	9-14
9781937-5	1998	We observed that Ang II is a vasoconstrictor of human coronary arteries, with a pEC50 value of 9.26 +/- 0.22 and Emax of 68.7 +/- 9.61% of potassium-induced contraction.	Potassium	139-148	angiotensinogen	Homo sapiens	17-23
9755212-7	1998	The variation in Ks across Igf2r is also repeatable.	Potassium	17-19	insulin like growth factor 2 receptor	Homo sapiens	27-32
9767539-1	1998	BACKGROUND: Potassium depletion increases HCO3- reabsorption in outer medullary collecting duct (OMCD) by activation of colonic (c) H-K-ATPase (HKA).	Potassium	12-21	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	132-142
9777733-3	1998	Neurons that express this gene, such as auditory brain stem neurons, have high-threshold voltage-dependent potassium currents that activate and deactivate unusually rapidly, and whose characteristics match those of the Kv3.1 subunit expressed heterologously.	Potassium	107-116	potassium voltage-gated channel subfamily C member 1	Homo sapiens	219-224
9767539-1	1998	BACKGROUND: Potassium depletion increases HCO3- reabsorption in outer medullary collecting duct (OMCD) by activation of colonic (c) H-K-ATPase (HKA).	Potassium	12-21	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	144-147
9767539-2	1998	The purpose of the current experiments was to examine the role of the isoforms of HKA in HCO3- reabsorption by terminal inner medullary collecting duct (IMCD) cells in potassium depletion.	Potassium	168-177	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	82-85
9767539-5	1998	RESULTS: Gastric (g) HKA mRNA decreased whereas colonic (c) HKA mRNA expression was heavily induced in terminal portion of inner medulla in potassium depleted rats.	Potassium	140-149	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	60-63
9767539-10	1998	CONCLUSIONS: The data indicate that gHKA is suppressed whereas cHKA is induced in potassium depletion and mediates increased HCO3- reabsorption in terminal IMCD.	Potassium	82-91	choline kinase alpha	Rattus norvegicus	63-67
9802016-0	1998	The Nha1 antiporter of Saccharomyces cerevisiae mediates sodium and potassium efflux.	Potassium	68-77	Nha1p	Saccharomyces cerevisiae S288C	4-8
9751185-5	1998	NPY overflow from the rat PVN was increased threefold by perfusion of a depolarizing concentration of potassium (50 mmol/L KCl).	Potassium	102-111	neuropeptide Y	Rattus norvegicus	0-3
9765514-6	1998	In oocytes expressing GRK5 instead of GRK3, both [D-Ala2,N-MePhe4, Gly-ol5]enkephalin and fentanyl, but not morphine, produced desensitization of MOR-activated potassium conductance.	Potassium	160-169	G protein-coupled receptor kinase 5	Homo sapiens	22-26
9794255-0	1998	Effects of high potassium and caffeine exposure on activities of Ca2+-dependent and Ca2+-independent protein kinase C in frog skeletal muscle.	Potassium	16-25	proline rich transmembrane protein 2	Homo sapiens	101-117
10065878-9	1998	Also, the presence of GLP-1 (7-36) amide in the synaptosome fraction and its calcium-dependent release by potassium stimulation, suggest that the peptide may act as a neurotransmitter although further electrophysiological and ultrastructural studies are needed to confirm this possibility.	Potassium	106-115	glucagon	Rattus norvegicus	22-27
9809870-7	1998	The effects of potassium deprivation on the activities of the TRH-like peptides were also investigated.	Potassium	15-24	thyrotropin releasing hormone	Mus musculus	62-65
9730830-0	1998	Catalytic significance of the specificity of divalent cations as KS* and kcat* cofactors for secreted phospholipase A2.	Potassium	65-67	phospholipase A2 group IB	Homo sapiens	102-118
9729621-0	1998	Differential regulation of potassium currents by FGF-1 and FGF-2 in embryonic Xenopus laevis myocytes.	Potassium	27-36	fibroblast growth factor 1 L homeolog	Xenopus laevis	49-54
9729621-0	1998	Differential regulation of potassium currents by FGF-1 and FGF-2 in embryonic Xenopus laevis myocytes.	Potassium	27-36	fibroblast growth factor 2 L homeolog	Xenopus laevis	59-64
9716705-0	1998	Losartan antagonism of angiotensin-II-induced potassium secretion across rat colon.	Potassium	46-55	angiotensinogen	Rattus norvegicus	23-37
9716705-1	1998	The effect of angiotensin II (ANG II) on potassium transport across the short-circuited rat distal colon was investigated using 86Rb+ as a tracer for unidirectional K+ fluxes.	Potassium	41-50	angiotensinogen	Rattus norvegicus	14-28
9716705-1	1998	The effect of angiotensin II (ANG II) on potassium transport across the short-circuited rat distal colon was investigated using 86Rb+ as a tracer for unidirectional K+ fluxes.	Potassium	41-50	angiotensinogen	Rattus norvegicus	30-36
9681500-0	1998	Calcitonin gene-related peptide stimulates potassium efflux through adenosine triphosphate-sensitive potassium channels and produces membrane hyperpolarization in osteoblastic UMR106 cells.	Potassium	43-52	calcitonin-related polypeptide alpha	Rattus norvegicus	0-31
9794255-5	1998	High potassium exposure not only caused a significant translocation of Ca2+-dependent PKC from the cytosol to the membrane, but also changed the distribution of Ca2+-independent PKC, although to a lesser extent.	Potassium	5-14	proline rich transmembrane protein 2	Homo sapiens	86-89
9794255-5	1998	High potassium exposure not only caused a significant translocation of Ca2+-dependent PKC from the cytosol to the membrane, but also changed the distribution of Ca2+-independent PKC, although to a lesser extent.	Potassium	5-14	proline rich transmembrane protein 2	Homo sapiens	178-181
9713846-0	1998	The influence of electric fields on the epileptiform bursts induced by high potassium in CA3 region of rat hippocampal slice.	Potassium	76-85	carbonic anhydrase 3	Rattus norvegicus	89-92
9713846-2	1998	The high potassium hippocampal slice model was used to generate spontaneous burst firing activity similar to interictal spikes in the pyramidal cell layer of CA3.	Potassium	9-18	carbonic anhydrase 3	Rattus norvegicus	158-161
9713846-8	1998	In conclusion, CA3 burst firing activity in high potassium concentration can therefore be altered by electric fields.	Potassium	49-58	carbonic anhydrase 3	Rattus norvegicus	15-18
9737727-4	1998	Adding excess soluble CD24 or removing CD24 from the cell surface with phosphatidylinositol-phospholipase C (PI-PLC) significantly reduced KS cell rolling on P-selectin.	Potassium	139-141	CD24 molecule	Homo sapiens	22-26
9737727-4	1998	Adding excess soluble CD24 or removing CD24 from the cell surface with phosphatidylinositol-phospholipase C (PI-PLC) significantly reduced KS cell rolling on P-selectin.	Potassium	139-141	CD24 molecule	Homo sapiens	39-43
9737727-4	1998	Adding excess soluble CD24 or removing CD24 from the cell surface with phosphatidylinositol-phospholipase C (PI-PLC) significantly reduced KS cell rolling on P-selectin.	Potassium	139-141	phospholipase C gamma 1	Homo sapiens	71-107
9737727-4	1998	Adding excess soluble CD24 or removing CD24 from the cell surface with phosphatidylinositol-phospholipase C (PI-PLC) significantly reduced KS cell rolling on P-selectin.	Potassium	139-141	phospholipase C gamma 1	Homo sapiens	109-115
9737727-4	1998	Adding excess soluble CD24 or removing CD24 from the cell surface with phosphatidylinositol-phospholipase C (PI-PLC) significantly reduced KS cell rolling on P-selectin.	Potassium	139-141	selectin P	Homo sapiens	158-168
9737727-5	1998	The ability of KS cells to roll on P-selectin was positively correlated with the CD24 expression level.	Potassium	15-17	selectin P	Homo sapiens	35-45
9737727-5	1998	The ability of KS cells to roll on P-selectin was positively correlated with the CD24 expression level.	Potassium	15-17	CD24 molecule	Homo sapiens	81-85
9737727-8	1998	Finally, KS cells rolled on vascular endothelium in vivo in a P-selectin-dependent manner.	Potassium	9-11	selectin P	Homo sapiens	62-72
9789303-4	1998	An increase in peripheral AVP results in suppression of amino acid permeability and increases in transport of sodium, potassium ions and water.	Potassium	118-127	arginine vasopressin	Homo sapiens	26-29
9888551-1	1998	Previous studies have shown that the hamster CYP11B2 gene promoter is under the influence of angiotensin II (AII), cAMP and potassium (K+).	Potassium	124-133	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	45-52
9675180-11	1998	However, experiments in normal low-potassium solutions showed that, in contrast to classical C-type inactivation, the inactivation of KvLQT1 is independent of extracellular potassium.	Potassium	35-44	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	134-140
9750011-12	1998	In contrast, potassium diet appears to be a determinant for the concomitant responses in plasma renin activity and renal sodium and potassium excretion.	Potassium	13-22	renin	Rattus norvegicus	96-101
9761383-6	1998	Renal calcium and potassium excretion were significantly elevated at plasma amylin concentrations of approximately 52 pM and 193 pM, respectively.	Potassium	18-27	islet amyloid polypeptide	Rattus norvegicus	76-82
9761383-7	1998	Higher concentrations of plasma amylin decreased plasma calcium and potassium and blunted urinary excretion of these electrolytes.	Potassium	68-77	islet amyloid polypeptide	Rattus norvegicus	32-38
9746905-0	1998	Enhancement of outward potassium current may participate in beta-amyloid peptide-induced cortical neuronal death.	Potassium	23-32	amyloid beta precursor protein	Homo sapiens	60-80
9671963-6	1998	A small subpopulation of freshly dissociated SC (less than 10%) at hyperpolarizing potentials elicited a potassium inward current instead, which in its kinetics closely resembled the inward rectifier (KIR) of mammalian SC.	Potassium	105-114	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	201-204
9714450-2	1998	Here we report effects of recombinant Nef and alpha-scorpion toxins on membrane potassium transport in human U251 astroglioma cells.	Potassium	80-89	S100 calcium binding protein B	Homo sapiens	38-41
9783915-5	1998	Although the release of both IR-ACTH and IR-CRH peptides from transfected AtT20 cells is stimulated in response to exposure to high potassium stimulation (51 mM KCl/SmM CaCl2), the sorting index (SI) suggests that mature ACTH is sorted to the regulated secretory pathway 2.1-fold more efficiently than mature CRH(1-41).	Potassium	132-141	pro-opiomelanocortin-alpha	Mus musculus	32-36
9717743-2	1998	In the present studies, we examined the initial aggregation process of lysozyme (initial crystallization process of lysozyme) in D2O/H2O with sodium ions or potassium ions, and investigated the relationship between the surface hydrophobicity and the aggregation rate of lysozyme.	Potassium	157-166	lysozyme	Homo sapiens	71-79
9651388-4	1998	269, 15195-15203) reported that potassium depletion of lipopolysaccharide-stimulated mouse macrophages induced by the potassium ionophore, nigericin, leads to the rapid release of mature interleukin-1beta (IL-1beta).	Potassium	32-41	interleukin 1 beta	Mus musculus	187-204
9651388-4	1998	269, 15195-15203) reported that potassium depletion of lipopolysaccharide-stimulated mouse macrophages induced by the potassium ionophore, nigericin, leads to the rapid release of mature interleukin-1beta (IL-1beta).	Potassium	32-41	interleukin 1 beta	Mus musculus	206-214
9651388-12	1998	So far, the mechanism by which reduced intracellular potassium ion concentration triggers p45 ICE processing is not known, but further investigation in this area could lead to the discovery of novel molecular targets whereby control of IL-1beta production might be effected.	Potassium	53-62	caspase 1	Homo sapiens	94-97
9651388-12	1998	So far, the mechanism by which reduced intracellular potassium ion concentration triggers p45 ICE processing is not known, but further investigation in this area could lead to the discovery of novel molecular targets whereby control of IL-1beta production might be effected.	Potassium	53-62	interleukin 1 beta	Homo sapiens	236-244
9671854-3	1998	We have compared potassium permeability in erythrocytes from ICD patients and from positive family history subjects (FICD) with control subjects.	Potassium	17-26	FIC domain protein adenylyltransferase	Homo sapiens	117-121
9717743-3	1998	The effect of sodium ions or potassium ions on the initial aggregation process of lysozyme in D2O was clearly different from H2O.	Potassium	29-38	lysozyme	Homo sapiens	82-90
9693779-0	1998	Sustained potassium currents in maturing CA1 hippocampal neurones.	Potassium	10-19	carbonic anhydrase 1	Rattus norvegicus	41-44
9635891-0	1998	Selective blockade of a slowly inactivating potassium current in striatal neurons by (+/-) 6-chloro-APB hydrobromide (SKF82958).	Potassium	44-53	arginyl aminopeptidase	Rattus norvegicus	100-103
9636228-4	1998	NGF secretion is increased in response to elevated glucose or potassium, but decreased in response to dibutyryl cAMP.	Potassium	62-71	nerve growth factor	Homo sapiens	0-3
9603927-3	1998	Recently we have identified two adjacent amino acid residues of the glutamate transporter GLT-1 that influence potassium coupling.	Potassium	111-120	solute carrier family 1 member 2	Homo sapiens	90-95
9614085-0	1998	Ectopic potassium uptake in trk1 trk2 mutants of Saccharomyces cerevisiae correlates with a highly hyperpolarized membrane potential.	Potassium	8-17	Trk1p	Saccharomyces cerevisiae S288C	28-32
9614085-0	1998	Ectopic potassium uptake in trk1 trk2 mutants of Saccharomyces cerevisiae correlates with a highly hyperpolarized membrane potential.	Potassium	8-17	Trk2p	Saccharomyces cerevisiae S288C	33-37
11245064-0	1998	Effects of beta-amyloid peptide on transient outward potassium current of acutely dissociated hippocampal neurons in CA1 sector in rats.	Potassium	53-62	carbonic anhydrase 1	Rattus norvegicus	117-120
9616219-11	1998	Further, the ACTH response to potassium and to forskolin was markedly blunted by the CRH antiserum as well as by the CRH antagonist, alpha-helical CRH(9-41).	Potassium	30-39	corticotropin releasing hormone	Rattus norvegicus	85-88
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	226-235	sodium voltage-gated channel alpha subunit 5	Homo sapiens	159-164
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	112-121	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	123-129
9616219-11	1998	Further, the ACTH response to potassium and to forskolin was markedly blunted by the CRH antiserum as well as by the CRH antagonist, alpha-helical CRH(9-41).	Potassium	30-39	corticotropin releasing hormone	Rattus norvegicus	117-120
9616219-11	1998	Further, the ACTH response to potassium and to forskolin was markedly blunted by the CRH antiserum as well as by the CRH antagonist, alpha-helical CRH(9-41).	Potassium	30-39	corticotropin releasing hormone	Rattus norvegicus	117-120
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	112-121	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	131-136
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	112-121	potassium voltage-gated channel subfamily H member 2	Homo sapiens	142-146
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	226-235	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	123-129
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	226-235	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	131-136
9654228-1	1998	INTRODUCTION: Inherited long QT syndrome (LQTS) recently has been associated with mutations in genes coding for potassium (KVLQT1, KCNE1, and HERG) or sodium (SCN5A) ion channels involved in regulating either sodium inward or potassium outward currents of heart cells, resulting in prolongation of the repolarization period.	Potassium	226-235	potassium voltage-gated channel subfamily H member 2	Homo sapiens	142-146
9603200-8	1998	Prostaglandin E2 and 4-aminopyridine (a blocker of outward potassium currents) also significantly reduced interleukin-1beta production.	Potassium	59-68	interleukin 1 beta	Rattus norvegicus	106-123
9626295-8	1998	However, when either thrombolytic was infused concomitantly with thrombin (1 or 5 U), brain water, sodium, and potassium content all demonstrated a potentiation of thrombin-induced brain injury (P < 0.05).	Potassium	111-120	coagulation factor II	Rattus norvegicus	164-172
9585559-2	1998	In the bovine Hsc70 ATPase fragment, mutation of cysteine 17 or aspartic acid 206 to lysine potentially allows the replacement of an active site potassium ion with the epsilon-amino nitrogen.	Potassium	145-154	heat shock protein family A (Hsp70) member 8	Bos taurus	14-26
9705037-9	1998	Partial correlations of SBP and DBP with the 3-day averages were 0.257 (P < 0.01) and 0.210 (P < 0.05) for sodium; 0.223 (P < 0.05) and 0.222 (P < 0.05) for potassium; 0.127 and 0.091 for urinary volume; and -0.033 and 0.014 for creatinine.	Potassium	169-178	selenium binding protein 1	Homo sapiens	24-27
9727207-9	1998	The plasma potassium concentration was maintained by means of insulin receptors on erythrocytes.	Potassium	11-20	insulin	Homo sapiens	62-69
9572739-6	1998	These results and membrane potential measurements suggest that the AKT1 channel mediates potassium uptake from solutions that contain as little as 10 micromolar potassium.	Potassium	89-98	K+ transporter 1	Arabidopsis thaliana	67-71
9699805-1	1998	The urinary excretion levels of sodium (Na) and potassium (K) in cadmium (Cd)-exposed subjects as related with urinary beta2-microglobulin (beta2-MG) and Cd concentrations were investigated.	Potassium	48-57	beta-2-microglobulin	Homo sapiens	140-148
9572739-6	1998	These results and membrane potential measurements suggest that the AKT1 channel mediates potassium uptake from solutions that contain as little as 10 micromolar potassium.	Potassium	161-170	K+ transporter 1	Arabidopsis thaliana	67-71
9547221-0	1998	Somatodendritic depolarization-activated potassium currents in rat neostriatal cholinergic interneurons are predominantly of the A type and attributable to coexpression of Kv4.2 and Kv4.1 subunits.	Potassium	41-50	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	172-177
9547221-0	1998	Somatodendritic depolarization-activated potassium currents in rat neostriatal cholinergic interneurons are predominantly of the A type and attributable to coexpression of Kv4.2 and Kv4.1 subunits.	Potassium	41-50	potassium voltage-gated channel subfamily D member 1	Rattus norvegicus	182-187
9602050-4	1998	High potassium-induced cell proliferation was blocked by the mitogen-activated protein kinase kinase (MEK1) inhibitor (PD98059, 75 microM).	Potassium	5-14	mitogen activated protein kinase kinase 1	Rattus norvegicus	102-106
9566904-4	1998	Expression of the KS chimera resulted in its autophosphorylation, the phosphorylation of cellular proteins, the upregulation of T-cell activation markers, and the induction of interleukin-2 gene synthesis in a TCR-independent fashion.	Potassium	18-20	interleukin 2	Homo sapiens	176-189
9566904-5	1998	The KS chimera and downstream ZAP-70 or Syk substrates, such as SLP-76, were still phosphorylated when expressed in Lck-deficient JCaM1.6 T cells.	Potassium	4-6	lymphocyte cytosolic protein 2	Homo sapiens	64-70
9566904-5	1998	The KS chimera and downstream ZAP-70 or Syk substrates, such as SLP-76, were still phosphorylated when expressed in Lck-deficient JCaM1.6 T cells.	Potassium	4-6	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	116-119
9581776-5	1998	Injection of 4.6 ng of Vpu mRNA into these cells reduces endogenous potassium conductance by 50%.	Potassium	68-77	Vpu	Human immunodeficiency virus 1	23-26
9526000-2	1998	In AtT-20 cells transfected with rat cannabinoid receptor (CB1), the activation of an inwardly rectifying potassium current (Kir current) and depression of P/Q-type calcium channels by cannabinoids were prevented by stimulation of protein kinase C by 100 nM phorbol 12-myristate 13-acetate (PMA).	Potassium	106-115	cannabinoid receptor 1	Rattus norvegicus	59-62
9526005-4	1998	Using in vitro slices of cerebellum, we have found that basic fibroblast growth factor (bFGF) upregulates both Kv3.1a and Kv3.1b at this developmental stage, but that depolarization by elevated potassium concentrations is without effect.	Potassium	194-203	fibroblast growth factor 2	Rattus norvegicus	56-86
9526005-4	1998	Using in vitro slices of cerebellum, we have found that basic fibroblast growth factor (bFGF) upregulates both Kv3.1a and Kv3.1b at this developmental stage, but that depolarization by elevated potassium concentrations is without effect.	Potassium	194-203	fibroblast growth factor 2	Rattus norvegicus	88-92
9593865-2	1998	In the present in vivo microdialysis study, the effect of unilateral sciatic nerve section on basal and potassium-induced release of CCK-like (CCK-LI) immunoreactivity in the rat dorsal horn was investigated.	Potassium	104-113	cholecystokinin	Rattus norvegicus	133-136
9593865-2	1998	In the present in vivo microdialysis study, the effect of unilateral sciatic nerve section on basal and potassium-induced release of CCK-like (CCK-LI) immunoreactivity in the rat dorsal horn was investigated.	Potassium	104-113	cholecystokinin	Rattus norvegicus	143-146
9593865-3	1998	We also compared the effects of the CCK-B receptor antagonist CI988 on basal and potassium-stimulated CCK-LI release in intact animals and in chronically axotomized rats.	Potassium	81-90	cholecystokinin	Rattus norvegicus	102-105
9516148-2	1998	Several cytokines, including interleukin-6 (IL-6), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF) may be important for survival of KS cells.	Potassium	165-167	interleukin 6	Homo sapiens	29-42
9602152-7	1998	This in vitro cleavage data provides support to the hypothesis that calpromotin (NKEF-B), an erythron peroxiredoxin involved in the regulation of calcium-dependent potassium transport across the plasma membrane, is cleaved by calpain in vivo.	Potassium	164-173	peroxiredoxin 2	Homo sapiens	81-87
9575892-1	1998	To probe the role of the isoforms of H(+)-K(+)-ATPase (HKA) in potassium depletion (KD), rats were placed on a KD diet for 2 wk.	Potassium	63-72	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	37-53
9575892-1	1998	To probe the role of the isoforms of H(+)-K(+)-ATPase (HKA) in potassium depletion (KD), rats were placed on a KD diet for 2 wk.	Potassium	63-72	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	55-58
9516395-5	1998	RESULTS: Erythromycin and motilin increased a calcium-dependent outward potassium current and increased the open probability of KCa channels of cell- attached patches.	Potassium	72-81	promotilin	Oryctolagus cuniculus	26-33
9516148-2	1998	Several cytokines, including interleukin-6 (IL-6), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF) may be important for survival of KS cells.	Potassium	165-167	interleukin 6	Homo sapiens	44-48
9516148-2	1998	Several cytokines, including interleukin-6 (IL-6), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF) may be important for survival of KS cells.	Potassium	165-167	fibroblast growth factor 2	Homo sapiens	51-81
9522169-2	1998	A study has been made to know the effects of clozapine and clothiapine on the responses of rat isolated vas deferens to norepinephrine, dopamine and potassium, those of the rat isolated uterus to serotonin and potassium, and that of guinea pig isolated ileum to histamine.	Potassium	149-158	arginine vasopressin	Rattus norvegicus	104-107
9516148-2	1998	Several cytokines, including interleukin-6 (IL-6), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF) may be important for survival of KS cells.	Potassium	165-167	fibroblast growth factor 2	Homo sapiens	83-87
10099101-4	1998	Medications generally produce hyperkalemia either by causing redistribution of potassium (beta2 -adrenergic blockers, succinylcholine, digitalis overdose, hypertonic mannitol) or by impairing renal potassium excretion.	Potassium	79-88	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	90-95
9511103-5	1998	The thrombin-fibrinogen dissociation constant Ks served as the single adjustable parameter in a least-squares fitting of the model to experimental anticoagulation data.	Potassium	46-48	coagulation factor II, thrombin	Homo sapiens	4-12
9511103-5	1998	The thrombin-fibrinogen dissociation constant Ks served as the single adjustable parameter in a least-squares fitting of the model to experimental anticoagulation data.	Potassium	46-48	fibrinogen beta chain	Homo sapiens	13-23
9587066-6	1998	Mutations in KCNJ1 leading to loss of function of the potassium channel ROMK disrupt potassium recycling back to the tubule lumen and inhibit thereby the NKCC2 activity.	Potassium	54-63	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	13-18
9587066-6	1998	Mutations in KCNJ1 leading to loss of function of the potassium channel ROMK disrupt potassium recycling back to the tubule lumen and inhibit thereby the NKCC2 activity.	Potassium	54-63	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	72-76
9587066-6	1998	Mutations in KCNJ1 leading to loss of function of the potassium channel ROMK disrupt potassium recycling back to the tubule lumen and inhibit thereby the NKCC2 activity.	Potassium	54-63	solute carrier family 12 member 1	Homo sapiens	154-159
9479027-8	1998	These data are consistent with a model in which Y293 contributes to a potassium-binding site close to the outer mouth of the dSlo pore, while F294 contributes to an energy barrier near this site.	Potassium	70-79	slowpoke	Drosophila melanogaster	125-129
9546788-3	1998	Using gel permeation chromatography of the clinical grade hCG and urine concentrates from pregnant women, we demonstrate that an as yet unidentified hCG associated factor (HAF) with anti-HIV, anti-SIV, anti-KS and pro-hematopoietic activities elutes as two peaks corresponding to 15-30 kDa and 2-4 kDa.	Potassium	207-209	hypertrichosis 2 (generalised, congenital)	Homo sapiens	149-152
9538640-5	1998	It has been postulated recently that in many cases the resistancy toward vasopressin is not absolute and these partially vasopressin sensitive patients can be treated successfully by thiazide, and potassium sparing compounds, antiprostaglandin pain killers (non-steroid antiinflammatory drugs) and first of all dDAVP as well as combinations of these preparations.	Potassium	197-206	arginine vasopressin	Homo sapiens	73-84
9538640-5	1998	It has been postulated recently that in many cases the resistancy toward vasopressin is not absolute and these partially vasopressin sensitive patients can be treated successfully by thiazide, and potassium sparing compounds, antiprostaglandin pain killers (non-steroid antiinflammatory drugs) and first of all dDAVP as well as combinations of these preparations.	Potassium	197-206	arginine vasopressin	Homo sapiens	121-132
9454854-9	1998	The low-threshold dendrotoxin-sensitive sustained potassium current (IDS) is associated with principal cells that accommodate and is not expressed in those that fire repetitively.	Potassium	50-59	iduronate 2-sulfatase	Gallus gallus	69-72
9587734-5	1998	The serum level of potassium was observed to be 8.4 mequiv L-1.	Potassium	19-28	immunoglobulin kappa variable 1-16	Homo sapiens	59-62
9518260-8	1998	Proliferative growth levels of mitochondrial (Mn)SOD activities showed an activity spectrum ranging from lowest activity in AIDS-KS cells, to intermediate levels in matched, nonlesional cells from the AIDS-KS donors, to highest activities in HIV normal fibroblasts.	Potassium	129-131	superoxide dismutase 2	Homo sapiens	49-52
9518260-8	1998	Proliferative growth levels of mitochondrial (Mn)SOD activities showed an activity spectrum ranging from lowest activity in AIDS-KS cells, to intermediate levels in matched, nonlesional cells from the AIDS-KS donors, to highest activities in HIV normal fibroblasts.	Potassium	206-208	superoxide dismutase 2	Homo sapiens	49-52
9518260-9	1998	In contrast, following TNF-alpha challenge, the AIDS-KS and KS donor nonlesional cells showed a 11.89- and 5.86-fold respective increase in MnSOD activity, while the normal fibroblasts demonstrated a 1.35-fold decrease.	Potassium	53-55	tumor necrosis factor	Homo sapiens	23-32
9518260-9	1998	In contrast, following TNF-alpha challenge, the AIDS-KS and KS donor nonlesional cells showed a 11.89- and 5.86-fold respective increase in MnSOD activity, while the normal fibroblasts demonstrated a 1.35-fold decrease.	Potassium	53-55	superoxide dismutase 2	Homo sapiens	140-145
9478930-8	1998	As in adrenals cardiac 11beta-hydroxylase and aldosterone-synthase mRNAs were independently regulated by 1 week"s treatment with either low sodium and high potassium diet (which increased aldosterone synthase mRNA level only), angiotensin II (which raised level of both mRNAs), or adrenocorticotropin (which stimulated the 11beta-hydroxylase gene exclusively).	Potassium	156-165	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	46-66
9478930-8	1998	As in adrenals cardiac 11beta-hydroxylase and aldosterone-synthase mRNAs were independently regulated by 1 week"s treatment with either low sodium and high potassium diet (which increased aldosterone synthase mRNA level only), angiotensin II (which raised level of both mRNAs), or adrenocorticotropin (which stimulated the 11beta-hydroxylase gene exclusively).	Potassium	156-165	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	188-208
10407367-4	1998	Similarly, intravenous saline infusion (2 mmol/kg/60 min) resulted in remarkable elevation of plasma ANF levels in patients and in controls (28.89+/-4.72 pg/ml and 20.18+/-2.48 pg/ml, respectively) and in increased urinary sodium and potassium excretion rates in both groups.	Potassium	234-243	natriuretic peptide A	Homo sapiens	101-104
9518260-12	1998	Our data, which show that a perturbation in their cellular thiol redox status accentuates AIDS-KS cellular responsiveness to TNF-alpha, suggest a biochemical rationale for the recognized TNF-alpha AIDS-KS clinical correlation.	Potassium	95-97	tumor necrosis factor	Homo sapiens	125-134
9518260-12	1998	Our data, which show that a perturbation in their cellular thiol redox status accentuates AIDS-KS cellular responsiveness to TNF-alpha, suggest a biochemical rationale for the recognized TNF-alpha AIDS-KS clinical correlation.	Potassium	95-97	tumor necrosis factor	Homo sapiens	187-196
9509993-0	1998	Effects of barium on stimulus induced changes in extracellular potassium concentration in area CA1 of hippocampal slices from normal and pilocarpine-treated epileptic rats.	Potassium	63-72	carbonic anhydrase 1	Rattus norvegicus	95-98
9461611-7	1998	Analysis of NCKX2 function by fluorescent imaging of fura-2-loaded transfected cells demonstrated that NCKX2 is a potassium-dependent sodium/calcium exchanger.	Potassium	114-123	solute carrier family 24 member 2	Rattus norvegicus	12-17
9461611-7	1998	Analysis of NCKX2 function by fluorescent imaging of fura-2-loaded transfected cells demonstrated that NCKX2 is a potassium-dependent sodium/calcium exchanger.	Potassium	114-123	solute carrier family 24 member 2	Rattus norvegicus	103-108
9465105-5	1998	Kvbeta1 subunits reduce potassium currents through inactivation, whereas Kvbeta2 subunits enhance potassium currents by inhibiting the Kvbeta1-mediated inactivation and at the same time by promoting the surface expression of certain potassium channels.	Potassium	24-33	potassium voltage-gated channel subfamily A regulatory beta subunit 1	Homo sapiens	0-7
9465105-5	1998	Kvbeta1 subunits reduce potassium currents through inactivation, whereas Kvbeta2 subunits enhance potassium currents by inhibiting the Kvbeta1-mediated inactivation and at the same time by promoting the surface expression of certain potassium channels.	Potassium	98-107	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Homo sapiens	73-80
9465105-10	1998	Such distinct functional stoichiometry of Kvbeta1 and Kvbeta2 provides a molecular mechanism that is well suited to their contrasting activities of up-regulation or down-regulation of potassium currents.	Potassium	184-193	potassium voltage-gated channel subfamily A regulatory beta subunit 1	Homo sapiens	42-49
9465105-10	1998	Such distinct functional stoichiometry of Kvbeta1 and Kvbeta2 provides a molecular mechanism that is well suited to their contrasting activities of up-regulation or down-regulation of potassium currents.	Potassium	184-193	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Homo sapiens	54-61
9465111-0	1998	Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion.	Potassium	80-89	potassium voltage-gated channel subfamily C member 1	Homo sapiens	14-19
9486222-0	1998	Local upregulation of colonic angiotensin II receptors enhances potassium excretion in chronic renal failure.	Potassium	64-73	angiotensinogen	Rattus norvegicus	30-44
9504932-4	1998	That the mean of the synonymous sequence difference Ks which is defined as the number of synonymous substitution relative to the total number of synonymous sites, within the UbC and CHUB2 genes (0.192 +/- 0.096) is significantly less than Ks between these genes (0.602 +/- 0.057) provides direct evidence for concerted evolution.	Potassium	52-54	ubiquitin C	Homo sapiens	174-177
9556090-8	1998	Raising the serum potassium concentration can increase outward HERG potassium current and is effective in shortening the QTc of patients with HERG mutations.	Potassium	18-27	potassium voltage-gated channel subfamily H member 2	Homo sapiens	63-67
9556090-8	1998	Raising the serum potassium concentration can increase outward HERG potassium current and is effective in shortening the QTc of patients with HERG mutations.	Potassium	18-27	potassium voltage-gated channel subfamily H member 2	Homo sapiens	142-146
9556090-8	1998	Raising the serum potassium concentration can increase outward HERG potassium current and is effective in shortening the QTc of patients with HERG mutations.	Potassium	68-77	potassium voltage-gated channel subfamily H member 2	Homo sapiens	63-67
9504932-4	1998	That the mean of the synonymous sequence difference Ks which is defined as the number of synonymous substitution relative to the total number of synonymous sites, within the UbC and CHUB2 genes (0.192 +/- 0.096) is significantly less than Ks between these genes (0.602 +/- 0.057) provides direct evidence for concerted evolution.	Potassium	239-241	ubiquitin C	Homo sapiens	174-177
9504932-5	1998	Moreover, it also appears that concerted evolutionary events have been much more frequent in CHUB2 than in UbC, because Ks within CHUB2 (0.022 +/- 0.018) is much less than that within UbC (0.362 +/- 0.192).	Potassium	120-122	ubiquitin C	Homo sapiens	107-110
9437012-8	1998	Additionally, RGS4 markedly attenuates the mGluR5-mediated inhibition of potassium currents in hippocampal CA1 neurons.	Potassium	73-82	regulator of G-protein signaling 4	Rattus norvegicus	14-18
9443892-7	1998	Inhibition of clathrin assembly by either potassium depletion or hypertonic buffer inhibited vitronectin internalization, suggesting that vitronectin internalization occurred through coated pits.	Potassium	42-51	vitronectin	Homo sapiens	93-104
9635158-5	1998	Bradykinin (0.1-100 nM) dose dependently (from 1-3 nM upwards) relaxed endothelium-denuded arteries that had been precontracted with a thromboxane (TX) A2 analog (ONO-11113, 0.1 microM) or excess potassium (5 mM Ca2+ in K(+)-Krebs) at a neonatal Po2.	Potassium	196-205	kininogen 1	Homo sapiens	0-10
9437012-8	1998	Additionally, RGS4 markedly attenuates the mGluR5-mediated inhibition of potassium currents in hippocampal CA1 neurons.	Potassium	73-82	carbonic anhydrase 1	Rattus norvegicus	107-110
9437012-8	1998	Additionally, RGS4 markedly attenuates the mGluR5-mediated inhibition of potassium currents in hippocampal CA1 neurons.	Potassium	73-82	glutamate receptor, ionotropic, kainate 1	Mus musculus	43-49
9447989-1	1998	Deletion of TRK1 and TRK2 abolishes high-affinity K+ uptake in Saccharomyces cerevisiae, resulting in the inability to grow on typical synthetic growth medium unless it is supplemented with very high concentrations of potassium.	Potassium	218-227	Trk1p	Saccharomyces cerevisiae S288C	12-16
9463463-2	1998	Taken together, the properties of Kv4 channels compare best with those of low-voltage activating "A-currents" present in the neuronal somatodendritic compartment and widely reported across several types of central and peripheral neurons, as well as the (Ca2+-independent) transient outward potassium conductance of heart cells (Ito).	Potassium	290-299	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	34-37
9454795-0	1998	Dopamine D4 receptor mediated inhibition of potassium current in neurohypophysial nerve terminals.	Potassium	44-53	dopamine receptor D4	Rattus norvegicus	0-20
9447989-1	1998	Deletion of TRK1 and TRK2 abolishes high-affinity K+ uptake in Saccharomyces cerevisiae, resulting in the inability to grow on typical synthetic growth medium unless it is supplemented with very high concentrations of potassium.	Potassium	218-227	Trk2p	Saccharomyces cerevisiae S288C	21-25
9435265-3	1998	Recently, we have identified an amino acid residue of the glutamate transporter GLT-1 (Glu-404) that influences potassium coupling.	Potassium	112-121	solute carrier family 1 member 3	Rattus norvegicus	58-79
9430594-3	1998	Expression of KCNQ2 in frog (Xenopus laevis) oocytes led to potassium-selective currents that activated slowly with depolarization.	Potassium	60-69	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	14-19
9507190-2	1998	During potassium-induced depolarisations, a 93% increase in extracellular levels of NPY was observed.	Potassium	7-16	neuropeptide Y	Rattus norvegicus	84-87
9437375-11	1998	After 1 year of follow-up, 15 (10%) of 146 case patients remaining on a regimen of an ACE inhibitor developed severe hyperkalemia (potassium level > 6.0 mmol/L).	Potassium	131-140	angiotensin I converting enzyme	Homo sapiens	86-89
9435265-3	1998	Recently, we have identified an amino acid residue of the glutamate transporter GLT-1 (Glu-404) that influences potassium coupling.	Potassium	112-121	solute carrier family 1 member 2	Rattus norvegicus	80-85
9694346-0	1998	Potassium deprivation-induced apoptosis of cerebellar granule neurons: cytochrome c release in the absence of altered expression of Bcl-2 family proteins.	Potassium	0-9	cytochrome c, somatic	Homo sapiens	71-83
9440565-6	1998	RESULTS: There was significant (p < 0.05) subsensitivity of systemic beta2-AR responses (as AUC) following FM + PL: for heart rate (before vs after), 760 vs 340 beats (95% confidence interval [CI], 160 to 680), for tremor 0.39 vs 0.19 log units/h (95% CI, 0.01 to 0.41), and for potassium, -0.34 vs -0.19 mmol x h/L (95% CI, -0.04 to -0.28).	Potassium	282-291	adrenoceptor beta 2	Homo sapiens	72-80
9694346-5	1998	However, mitochondrial release of cytochrome c, which is thought to be controlled by Bcl-2 family proteins, is detected 5 h after switching the neurons to low potassium conditions.	Potassium	159-168	cytochrome c, somatic	Homo sapiens	34-46
9382934-0	1998	Neuropeptide Y inhibits ion secretion in intestinal epithelium by reducing chloride and potassium conductance.	Potassium	88-97	neuropeptide Y	Homo sapiens	0-14
9928879-3	1998	The ratio of K2/K1 was 0.80+/-0.04 in control tissues, but fell significantly to 0.26+/-0.08 when 100nM purified CGA was added prior to the second potassium pulse.	Potassium	147-156	chromogranin A	Rattus norvegicus	113-116
9770720-4	1998	When those patients who lost total body potassium were compared with those who had not, there was a significant increase in the baseline and 12-week C-reactive protein concentrations (p < 0.05).	Potassium	40-49	C-reactive protein	Homo sapiens	149-167
9770720-6	1998	There were significant correlations between the mean C-reactive protein concentration and the relative (r = -0.846, p < 0.001) and absolute (r = -0.806, p < 0.001) change in total body potassium over the follow-up period.	Potassium	191-200	C-reactive protein	Homo sapiens	53-71
9459288-8	1998	Insulin is the most reliable agent for promoting transcellular shift of potassium.	Potassium	72-81	insulin	Homo sapiens	0-7
9460706-6	1998	Another point raised by the present results is the possible role of BDNF, acting in an autocrine or paracrine manner, in the trophic effect of high potassium concentration.	Potassium	148-157	brain-derived neurotrophic factor	Rattus norvegicus	68-72
9460706-7	1998	Indeed, repeated additions of BDNF to the culture medium have a trophic effect on cerebellar granule neurons but reproduce only partially the survival effect observed with 25 mM K+ conditions, suggesting that the increased expression of BDNF is not the only mechanism responsible for the trophic effects of high potassium.	Potassium	312-321	brain-derived neurotrophic factor	Rattus norvegicus	30-34
9477571-4	1998	Interestingly, AtKUP1 and AtKUP2 are able to complement the potassium transport deficiency of an E. coli triple mutant.	Potassium	60-69	potassium transporter 1	Arabidopsis thaliana	15-21
9477571-4	1998	Interestingly, AtKUP1 and AtKUP2 are able to complement the potassium transport deficiency of an E. coli triple mutant.	Potassium	60-69	potassium transporter 2	Arabidopsis thaliana	26-32
9477571-5	1998	In addition, transgenic Arabidopsis suspension cells overexpressing AtKUP1 showed increased Rb+ uptake at micromolar concentrations with an apparent K(m) of approximately 22 microM, indicating that AtKUP1 encodes a high-affinity potassium uptake activity in vivo.	Potassium	229-238	potassium transporter 1	Arabidopsis thaliana	68-74
9452013-0	1997	Tumor necrosis factor enhancement of transient outward potassium currents in cultured rat cortical neurons.	Potassium	55-64	tumor necrosis factor-like	Rattus norvegicus	0-21
9477571-5	1998	In addition, transgenic Arabidopsis suspension cells overexpressing AtKUP1 showed increased Rb+ uptake at micromolar concentrations with an apparent K(m) of approximately 22 microM, indicating that AtKUP1 encodes a high-affinity potassium uptake activity in vivo.	Potassium	229-238	potassium transporter 1	Arabidopsis thaliana	198-204
9391005-4	1997	On high potassium depolarization, the labeling of BDNF and TrkB mRNA extends on average to 68% of the dendritic length.	Potassium	8-17	brain derived neurotrophic factor	Homo sapiens	50-54
9391005-4	1997	On high potassium depolarization, the labeling of BDNF and TrkB mRNA extends on average to 68% of the dendritic length.	Potassium	8-17	neurotrophic receptor tyrosine kinase 2	Homo sapiens	59-63
9407042-6	1997	Patch-clamp recordings of hKCa4-transfected HEK 293 cells reveal a large voltage-independent, inwardly rectifying potassium current that is blocked by externally applied tetraethylammonium (Kd = 30 +/- 7 mM), charybdotoxin (Kd = 10 +/- 1 nM), and clotrimazole (Kd = 387 +/- 34 nM), but is resistant to apamin, iberiotoxin, kaliotoxin, scyllatoxin (Kd > 1 microM), and margatoxin (Kd > 100 nM).	Potassium	114-123	potassium calcium-activated channel subfamily N member 4	Homo sapiens	26-31
9407042-7	1997	Single hKCa4 channels have a conductance of 33 +/- 2 picosiemens in symmetrical potassium solutions.	Potassium	80-89	potassium calcium-activated channel subfamily N member 4	Homo sapiens	7-12
9452013-2	1997	Treatment of neurons with TNF resulted in an increase in outward potassium current density, dependent upon the concentration of TNF and the incubation time, without affecting other membrane currents such as barium and N-methyl-D-aspartate (NMDA).	Potassium	65-74	tumor necrosis factor	Rattus norvegicus	26-29
9452013-2	1997	Treatment of neurons with TNF resulted in an increase in outward potassium current density, dependent upon the concentration of TNF and the incubation time, without affecting other membrane currents such as barium and N-methyl-D-aspartate (NMDA).	Potassium	65-74	tumor necrosis factor	Rattus norvegicus	128-131
9452013-3	1997	Long exposures (12-48 hr) to TNF (10-100 ng/ml) increased transient outward potassium current (A-current) density without affecting the parameters of activation and inactivation of the current.	Potassium	76-85	tumor necrosis factor	Rattus norvegicus	29-32
9464452-5	1997	These data suggest that Cdc42, Rac, Ras, and/or Rap (but not Rho) may be needed for glucose- or potassium-mediated secretion.	Potassium	96-105	cell division cycle 42	Rattus norvegicus	24-29
9426226-3	1997	A comparison of the dose-response curves and of the maximum currents obtained indicates that SSTR2 couples most efficiently to this effector, supporting the notion that SSTR2 is involved in activation of potassium conductances by SST in vivo.	Potassium	204-213	somatostatin receptor 2	Rattus norvegicus	93-98
9426226-3	1997	A comparison of the dose-response curves and of the maximum currents obtained indicates that SSTR2 couples most efficiently to this effector, supporting the notion that SSTR2 is involved in activation of potassium conductances by SST in vivo.	Potassium	204-213	somatostatin receptor 2	Rattus norvegicus	169-174
9497875-12	1997	There were no significant changes in plasma catecholamine concentrations with either infusion but potassium concentrations were significantly (P < 0.05) reduced during the IGF-I infusion.	Potassium	98-107	insulin like growth factor 1	Homo sapiens	175-180
9497875-14	1997	IGF-I and insulin under conditions of adequate substrate supply have acute effects on IGFBP-1 and potassium physiology, but have little effect on IGFBP-3, ALS or catecholamines.	Potassium	98-107	insulin like growth factor 1	Homo sapiens	0-5
9497875-14	1997	IGF-I and insulin under conditions of adequate substrate supply have acute effects on IGFBP-1 and potassium physiology, but have little effect on IGFBP-3, ALS or catecholamines.	Potassium	98-107	insulin	Homo sapiens	10-17
9422800-0	1997	Cortistatin increase of a potassium conductance in rat locus coeruleus in vitro.	Potassium	26-35	cortistatin	Rattus norvegicus	0-11
9534323-11	1997	In conclusion, chronic treatment with ACE-inhibitors does not enhance the excretion of sodium in congestive heart failure but just mitigates potassium loss.	Potassium	141-150	angiotensin I converting enzyme	Homo sapiens	38-41
9464452-5	1997	These data suggest that Cdc42, Rac, Ras, and/or Rap (but not Rho) may be needed for glucose- or potassium-mediated secretion.	Potassium	96-105	LDL receptor related protein associated protein 1	Rattus norvegicus	48-51
9464452-8	1997	Recent findings indicate that the carboxyl methylation of Cdc42 is stimulated by only glucose, whereas that of Rap (Kowluru et al., J Clin Invest 98: 540-555, 1996) and Rac (present study) are regulated by glucose or potassium.	Potassium	217-226	cell division cycle 42	Rattus norvegicus	58-63
9652977-6	1997	It is shown that: (1) basal release was not affected by a short-term incubation with neLC; (2) secretion induced by corticotropin-releasing factor (CRF) and other secretagogues (phorbol ester, potassium ion or calcium ionophore) was inhibited by neLC; (3) GC inhibition of CRF-stimulated release was reverted by a monoclonal anti-neLC antibody; (4) rhLC2, rhLC5 and the fragment 212-234 of rhLC5 were without effect.	Potassium	193-202	corticotropin releasing hormone	Mus musculus	116-146
9367159-2	1997	The enzymes that produce PtdIns-4,5-P2 in vitro fall into two related subfamilies (type I and type II PtdInsP-5-OH kinases, or PIP(5)Ks) based on their enzymatic properties and sequence similarities".	Potassium	133-135	prolactin induced protein	Homo sapiens	127-130
9360571-1	1997	STUDY OBJECTIVE: To highlight the dangers of a precipitous rise in serum potassium levels in patients at risk for renal insufficiency, already receiving an angiotensin-converting enzyme (ACE) inhibitor, who are given a potassium-sparing diuretic.	Potassium	73-82	angiotensin I converting enzyme	Homo sapiens	156-185
9360571-1	1997	STUDY OBJECTIVE: To highlight the dangers of a precipitous rise in serum potassium levels in patients at risk for renal insufficiency, already receiving an angiotensin-converting enzyme (ACE) inhibitor, who are given a potassium-sparing diuretic.	Potassium	73-82	angiotensin I converting enzyme	Homo sapiens	187-190
9360571-1	1997	STUDY OBJECTIVE: To highlight the dangers of a precipitous rise in serum potassium levels in patients at risk for renal insufficiency, already receiving an angiotensin-converting enzyme (ACE) inhibitor, who are given a potassium-sparing diuretic.	Potassium	219-228	angiotensin I converting enzyme	Homo sapiens	156-185
9494556-2	1997	The Ks for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.077 mM in the control system, the value decreased by 14-38% in the DDP treated systems.	Potassium	4-6	acetylcholinesterase (Cartwright blood group)	Homo sapiens	64-68
9346924-7	1997	All three versions of Hsc70 possess similar ATP-dependent conformational shifts, and all show potassium ion dependence.	Potassium	94-103	heat shock protein family A (Hsp70) member 8	Bos taurus	22-27
9421167-0	1997	Substance P modulates sensory action potentials in the lamprey via a protein kinase C-mediated reduction of a 4-aminopyridine-sensitive potassium conductance.	Potassium	136-145	tachykinin precursor 1	Homo sapiens	0-11
9326665-4	1997	Expression of hIK1 in Xenopus oocytes gave rise to inwardly rectifying potassium currents, which were activated by submicromolar concentrations of intracellular calcium (K0.5 = 0.3 microM).	Potassium	71-80	potassium calcium-activated channel subfamily N member 4	Homo sapiens	14-18
9314540-4	1997	Protein synthesis also decreased rapidly in both wild-type and Bax-deficient granule cells to 50% of control within 12 h after switching to 5 mM potassium.	Potassium	145-154	BCL2-associated X protein	Mus musculus	63-66
9326866-11	1997	We found close correlations between the serum potassium and creatine kinase concentrations, between the serum myoglobin and potassium concentrations, and between the serum myoglobin and creatine kinase concentrations.	Potassium	124-133	myoglobin	Homo sapiens	110-119
9302275-4	1997	Co-expression of KvLQT1 with the IsK protein elicits slowly activating potassium currents resembling the cardiac Iks current.	Potassium	71-80	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	17-23
9302275-4	1997	Co-expression of KvLQT1 with the IsK protein elicits slowly activating potassium currents resembling the cardiac Iks current.	Potassium	71-80	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	33-36
9425994-10	1997	The inhibitory effect of ET-1 on nitric-oxide-mediated dilation could be mimicked with high potassium (65 +/- 6 microm), but not with phenylephrine (74 +/- 8 microm)-induced constriction.	Potassium	92-101	endothelin 1	Rattus norvegicus	25-29
9312073-1	1997	Calexcitin/cp20 is a low molecular weight GTP- and Ca2+-binding protein, which is phosphorylated by protein kinase C during associative learning, and reproduces many of the cellular effects of learning, such as the reduction of potassium currents in neurons.	Potassium	228-237	lymphocyte cytosolic protein, molecular weight 20kD	Homo sapiens	11-15
9322807-7	1997	Preincubation with metformin also induced an attenuating (vasodilating-like) action of insulin on arterial tissue rings contracted by potassium.	Potassium	134-143	insulin	Homo sapiens	87-94
9322807-8	1997	Conversely, glyburide induced an accentuating action of insulin on potassium-mediated contractions.	Potassium	67-76	insulin	Homo sapiens	56-63
9337622-4	1997	Potassium leakage and hemolysis were light and BCA dose dependent.	Potassium	0-9	B cell linker	Homo sapiens	47-50
9629425-6	1997	Familial episodic ataxias with (EA1-chromosome 12p) and without (chromosome 19p-EA2) myokimia were identified, the first one caused by point mutations in the gene encoding the KCNA1 potassium voltage-gated channel.	Potassium	182-191	potassium voltage-gated channel subfamily A member 1	Homo sapiens	176-181
9323054-2	1997	It has been discovered recently that the KvLQT1 and minK proteins functionally interact to generate a current with biophysical properties similar to I(Ks), the slowly activating delayed-rectifier cardiac potassium current.	Potassium	151-153	ADP ribosylation factor GTPase activating protein 1 L homeolog	Xenopus laevis	41-47
9323054-3	1997	Since I(Ks) modulates the repolarization of cardiac action potentials it is reasonable to hypothesize that mutations in KvLQT1 reduce I(Ks), resulting in the prolongation of cardiac action potential duration.	Potassium	8-10	ADP ribosylation factor GTPase activating protein 1 L homeolog	Xenopus laevis	120-126
9323054-3	1997	Since I(Ks) modulates the repolarization of cardiac action potentials it is reasonable to hypothesize that mutations in KvLQT1 reduce I(Ks), resulting in the prolongation of cardiac action potential duration.	Potassium	136-138	ADP ribosylation factor GTPase activating protein 1 L homeolog	Xenopus laevis	120-126
9315692-3	1997	We show that the model protein, hexaarginine-tagged green fluorescent protein (GFP), binds to mica via its Arg-tag based on ion exchange of naturally occurring potassium cations.	Potassium	160-169	MHC class I polypeptide-related sequence A	Homo sapiens	94-98
9372266-8	1997	A "nondestructive" method of screening cultured cells for their expression of c-NOS was established using depolarization with medium containing 50 mM potassium ion.	Potassium	150-159	nitric oxide synthase 3	Rattus norvegicus	78-83
9321906-7	1997	However, when Na+/H+ exchange was inhibited with EIPA, both bafilomycin A1 sensitive and potassium dependent, Sch-28080-sensitive components of pHi recovery were present.	Potassium	89-98	glucose-6-phosphate isomerase	Oryctolagus cuniculus	144-147
9231793-10	1997	Leptin, 10 microg/h, significantly decreased urine osmolality, increased water intake, and reduced renal potassium excretion compared with vehicle-infused rats.	Potassium	105-114	leptin	Rattus norvegicus	0-6
9261472-7	1997	One of the p53 positive AIDS-KS samples showed mobilized shifts in exon 6 suggestive of a mutation.	Potassium	29-31	tumor protein p53	Homo sapiens	11-14
9310457-7	1997	In three of three cells, addition of 2 mM barium was associated with an inward current, and the TRH-induced inward current was also suppressed, suggesting the presence of a resting barium- and TRH-sensitive potassium conductance.	Potassium	207-216	thyrotropin releasing hormone	Rattus norvegicus	96-99
9310457-7	1997	In three of three cells, addition of 2 mM barium was associated with an inward current, and the TRH-induced inward current was also suppressed, suggesting the presence of a resting barium- and TRH-sensitive potassium conductance.	Potassium	207-216	thyrotropin releasing hormone	Rattus norvegicus	193-196
9303580-11	1997	The reductions in IsK caused by propofol and thiopentone are consistent with the previously reported effects of these anaesthetics on I(Ks) in the heart and support the hypothesis that the min K protein contributes to the molecular basis of the cardiac I(Ks) channel.	Potassium	136-138	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	18-21
9303580-11	1997	The reductions in IsK caused by propofol and thiopentone are consistent with the previously reported effects of these anaesthetics on I(Ks) in the heart and support the hypothesis that the min K protein contributes to the molecular basis of the cardiac I(Ks) channel.	Potassium	255-257	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	18-21
9449035-6	1997	Specific micronutrients, such as potassium, magnesium and zinc also appear to be important for optimal IGF-I synthesis and anabolic effects in animal models.	Potassium	33-42	insulin like growth factor 1	Homo sapiens	103-108
9280211-0	1997	Effect of administered potassium on the renin-aldosterone axis in young blacks compared with whites.	Potassium	23-32	renin	Homo sapiens	40-45
9280211-14	1997	A lower intake of potassium could at least partially account for the suppression of the renin-aldosterone system in blacks.	Potassium	18-27	renin	Homo sapiens	88-93
9280884-5	1997	Considering the probable long elimination period of digitalis and the potentially life-threatening situation the patients were given digoxin-specific antibody (Fab) fragments with potassium replacement therapy.	Potassium	180-189	FA complementation group B	Homo sapiens	160-163
9306093-5	1997	In an effort to examine the H-2 genes of RadLV-susceptible mice for the presence of the H-2 BF1 binding target, we have cloned class I genes from the highly susceptible B10.S mouse strain and have identified both the Ds and the Ks genes.	Potassium	228-230	histocompatibility-2, MHC	Mus musculus	88-91
9272507-12	1997	Along the same line of development of gene-specific therapy, recent data demonstrated that an increase in the extracellular concentration of potassium shortens the QT interval in LQT2 patients suggesting that intervention aimed at increasing potassium plasma levels may represent a specific treatment for LQT2.	Potassium	141-150	potassium voltage-gated channel subfamily H member 2	Homo sapiens	179-183
9272507-12	1997	Along the same line of development of gene-specific therapy, recent data demonstrated that an increase in the extracellular concentration of potassium shortens the QT interval in LQT2 patients suggesting that intervention aimed at increasing potassium plasma levels may represent a specific treatment for LQT2.	Potassium	141-150	potassium voltage-gated channel subfamily H member 2	Homo sapiens	305-309
9272507-12	1997	Along the same line of development of gene-specific therapy, recent data demonstrated that an increase in the extracellular concentration of potassium shortens the QT interval in LQT2 patients suggesting that intervention aimed at increasing potassium plasma levels may represent a specific treatment for LQT2.	Potassium	242-251	potassium voltage-gated channel subfamily H member 2	Homo sapiens	179-183
9272507-12	1997	Along the same line of development of gene-specific therapy, recent data demonstrated that an increase in the extracellular concentration of potassium shortens the QT interval in LQT2 patients suggesting that intervention aimed at increasing potassium plasma levels may represent a specific treatment for LQT2.	Potassium	242-251	potassium voltage-gated channel subfamily H member 2	Homo sapiens	305-309
9263593-2	1997	A high concentration of potassium (26 mM) in the culture medium and BDNF can effectively prevent this apoptosis.	Potassium	24-33	brain-derived neurotrophic factor	Rattus norvegicus	68-72
9262339-4	1997	In addition, both potassium- (100 mM, K+) and d-amphetamine (250 microM)-induced DA overflow were augmented in the striatum and nucleus accumbens of the aged rats injected with GDNF.	Potassium	18-28	glial cell derived neurotrophic factor	Rattus norvegicus	177-181
9263991-0	1997	The IGF-I axis in kidney and skeletal muscle of potassium deficient rats.	Potassium	48-57	insulin-like growth factor 1	Rattus norvegicus	4-9
9240458-1	1997	In the rat adipocyte, insulin increases potassium uptake by a preferential activation of the alpha2 isoform of the Na,K-ATPase.	Potassium	40-49	insulin	Homo sapiens	22-29
9216439-7	1997	The antihypertensive effect of increased potassium intake appears to be mediated by several factors, which include enhancing natriuresis, modulating baroreflex sensitivity, direct vasodilation, or lowering cardiovascular reactivity to norepinephrine or angiotensin II.	Potassium	41-50	angiotensinogen	Homo sapiens	253-267
9230439-0	1997	A minK-HERG complex regulates the cardiac potassium current I(Kr).	Potassium	42-51	potassium voltage-gated channel subfamily H member 2	Homo sapiens	7-11
9263909-0	1997	Corticotropin releasing hormone inhibits an inwardly rectifying potassium current in rat corticotropes.	Potassium	64-73	corticotropin releasing hormone	Rattus norvegicus	0-31
9263910-4	1997	NPY (0.1 microM) depolarized arterial smooth muscle cells from -55 to -47 mV and increased wall tension by 0.22 N m-1, representing 11% of the contraction elicited by a high-potassium solution.	Potassium	174-183	neuropeptide Y	Rattus norvegicus	0-3
9247743-5	1997	18-month old animals showed a reduced ability to release both NPY and noradrenaline to a potassium depolarisation stimulus.	Potassium	89-98	neuropeptide Y	Rattus norvegicus	62-65
9227634-8	1997	However, the expression of cHKA mRNA in the kidney was decreased by approximately 80% in potassium-depleted (HPX+KD) rats (P < 0.01 vs. KD only).	Potassium	89-98	choline kinase alpha	Rattus norvegicus	27-31
9297927-4	1997	Both LQT1 and LQT2 relate with inward rectifying potassium currents and is repolarization related, therefore, it is speculate that patients of LQT1 and LQT2 may have an abnormal T-U-wave on their surface ECG.	Potassium	49-58	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	5-9
9297927-4	1997	Both LQT1 and LQT2 relate with inward rectifying potassium currents and is repolarization related, therefore, it is speculate that patients of LQT1 and LQT2 may have an abnormal T-U-wave on their surface ECG.	Potassium	49-58	potassium voltage-gated channel subfamily H member 2	Homo sapiens	14-18
9297927-4	1997	Both LQT1 and LQT2 relate with inward rectifying potassium currents and is repolarization related, therefore, it is speculate that patients of LQT1 and LQT2 may have an abnormal T-U-wave on their surface ECG.	Potassium	49-58	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	143-147
9297927-4	1997	Both LQT1 and LQT2 relate with inward rectifying potassium currents and is repolarization related, therefore, it is speculate that patients of LQT1 and LQT2 may have an abnormal T-U-wave on their surface ECG.	Potassium	49-58	potassium voltage-gated channel subfamily H member 2	Homo sapiens	152-156
9174520-10	1997	Insulin-treated animals were characterized by improved cardiodynamics and hemodynamics, increased myocardial glucose uptake, and decreased serum potassium.	Potassium	145-154	insulin	Canis lupus familiaris	0-7
9227634-10	1997	Thus potassium depletion increases expression of cHKA in the kidney but not that of gHKA or NHE isoforms.	Potassium	5-14	choline kinase alpha	Rattus norvegicus	49-53
9179597-9	1997	This DTX-sensitive current appeared to be a sustained outward potassium current, consistent with the suggestion that the Shaker-like potassium channel Kv1.6 underlies a portion of the delayed rectifier potassium current in cultured mouse cortical astrocytes.	Potassium	62-71	potassium voltage-gated channel, shaker-related, subfamily, member 6	Mus musculus	151-156
9151721-8	1997	Chronic depolarization with 40 mM potassium stimulated the PACAP secretory rate 10- to 20-fold, with concomitant increases in cellular PACAP peptide and mRNA levels.	Potassium	34-43	adenylate cyclase activating polypeptide 1	Rattus norvegicus	59-64
9151721-8	1997	Chronic depolarization with 40 mM potassium stimulated the PACAP secretory rate 10- to 20-fold, with concomitant increases in cellular PACAP peptide and mRNA levels.	Potassium	34-43	adenylate cyclase activating polypeptide 1	Rattus norvegicus	135-140
9238521-2	1997	The Michaelis-Menten constant (Ks) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.072 mM in the control system, a value decreased by 38-55% in the sevin treated systems.	Potassium	31-33	acetylcholinesterase	Camelus bactrianus	92-96
15810224-0	1997	[Determination of calcium, magnesium and potassium in nurtured cell by AAS with quick-pulsed nebulization technique and NaOH base digestion].	Potassium	41-50	FYVE, RhoGEF and PH domain containing 1	Homo sapiens	71-74
15810224-2	1997	Its Calcium magensium and potassium content are determined by AAS.	Potassium	26-35	FYVE, RhoGEF and PH domain containing 1	Homo sapiens	62-65
9151757-7	1997	Over the range of 40 to 34 degrees C, the Q10 values for evoked release for CGRP were 11.3 (potassium) and 39.7 (capsaicin) and for glutamate, 5.	Potassium	92-101	calcitonin-related polypeptide alpha	Rattus norvegicus	76-80
9186877-6	1997	Plasma insulin rose to a level known to induce cellular potassium uptake (39.2 +/- 7.7 mU/ml) after 60 minutes of drug therapy and remained at this level for four hours.	Potassium	56-65	insulin	Homo sapiens	7-14
9185100-8	1997	Finally, ANP infusion augmented the urinary losses of the main solutes retained in CRF (urea, potassium, phosphorous) with a significant decrease in the plasma levels.	Potassium	94-103	natriuretic peptide A	Homo sapiens	9-12
9153214-1	1997	Deletion of the potassium transporter genes TRK1 and TRK2 impairs potassium uptake in Saccharomyces cerevisiae, resulting in a greatly increased requirement for the ion and the inability to grow on low pH medium.	Potassium	16-25	Trk1p	Saccharomyces cerevisiae S288C	44-48
9185688-6	1997	It was concluded that NPY hyperpolarized submucosal neurons of the guinea-pig descending colon, possibly via a direct action on postsynaptic Y1-receptor and increasing potassium conductance.	Potassium	168-177	pro-neuropeptide Y	Cavia porcellus	22-25
9187360-1	1997	Fatty acid (FA) uniport via mitochondrial uncoupling protein (UcP) was detected fluorometrically with PBFI, potassium-binding benzofuran phthalate and SPQ, 6-methoxy-N-(3-sulfopropyl)-quinolinium, indicating K+ and H+, respectively.	Potassium	108-117	uncoupling protein 1	Homo sapiens	62-65
9153214-1	1997	Deletion of the potassium transporter genes TRK1 and TRK2 impairs potassium uptake in Saccharomyces cerevisiae, resulting in a greatly increased requirement for the ion and the inability to grow on low pH medium.	Potassium	16-25	Trk2p	Saccharomyces cerevisiae S288C	53-57
9115204-3	1997	The peptide induced a 100-fold enhancement of potassium currents by activating the Ras-Raf and adenylyl cyclase-adenosine 3",5"-monophosphate (cAMP) pathways.	Potassium	46-55	Raf oncogene	Drosophila melanogaster	87-90
9189911-2	1997	The biophysical properties of KOR are similar to those described for the S-channel (KS) which underlies simple forms of non-associative learning in the marine mollusc Aplysia.	Potassium	84-86	opioid receptor kappa 1	Homo sapiens	30-33
9176335-2	1997	The present studies were designed to determine the effects of vasopressin (VP) and oxytocin (OT) AODNs on osmotically or potassium-stimulated VP and OT release from perifused hypothalamoneurohypophysial (HNS) explants.	Potassium	121-130	arginine vasopressin	Homo sapiens	62-73
9176378-1	1997	We studied the renal expression of the insulin-like growth factor (IGF) system to gain a better perspective of its potential role in the hyperplastic adaptation of the distal nephron to potassium deficiency.	Potassium	186-195	insulin-like growth factor 1	Rattus norvegicus	39-65
9176378-6	1997	Immunohistochemistry performed using a specific IGFBP-1 antibody revealed hyperplasia of distal nephron segments along with an increase in IGFBP-1 in potassium-depleted rats.	Potassium	150-159	insulin-like growth factor binding protein 1	Rattus norvegicus	48-55
9176378-1	1997	We studied the renal expression of the insulin-like growth factor (IGF) system to gain a better perspective of its potential role in the hyperplastic adaptation of the distal nephron to potassium deficiency.	Potassium	186-195	insulin-like growth factor 1	Rattus norvegicus	67-70
9176378-4	1997	At day 10 mRNA for IGFBP-1 in potassium-deficient animals averaged 2.07 +/- 0.53 (mean +/- SD, relative densitometry units) compared with 0.89 +/- 0.26 in control rats (n = 4, P = 0.002).	Potassium	30-39	insulin-like growth factor binding protein 1	Rattus norvegicus	19-26
9176372-0	1997	Differential regulation of CHIF mRNA by potassium intake and aldosterone.	Potassium	40-49	FXYD domain-containing ion transport regulator 4	Rattus norvegicus	27-31
9176378-5	1997	Conversely, IGFBP-3, a binding protein whose mRNA has been localized to the interstitial compartment, averaged 2.40 +/- 0.02 in potassium-deficient rats and 4.77 +/- 0.05 in controls (n = 4, P < 0.03) at day 10 of treatment.	Potassium	128-137	insulin-like growth factor binding protein 3	Rattus norvegicus	12-19
9176378-6	1997	Immunohistochemistry performed using a specific IGFBP-1 antibody revealed hyperplasia of distal nephron segments along with an increase in IGFBP-1 in potassium-depleted rats.	Potassium	150-159	insulin-like growth factor binding protein 1	Rattus norvegicus	139-146
9108097-8	1997	Coexpression of minK with KvLQT1 results in a conductance with pharmacological and biophysical properties more similar to I(Ks) than other known delayed rectifier K+ currents in the heart.	Potassium	124-126	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	26-32
9176189-10	1997	There were positive nonlinear relationships between tissue Ks and circulating concentrations of insulin.	Potassium	59-61	insulin	Sus scrofa	96-103
9152987-2	1997	This study tested the effects of a novel pan-ICE family inhibitor, bocaspartyl(OMe)-fluoromethylketone (boc-Asp-CH2F), against low potassium-induced apoptosis of cultured rat cerebellar granule neurons (CGN).	Potassium	131-140	caspase 1	Rattus norvegicus	45-48
9175891-8	1997	Consistent with the reduction in PSCs, ENK inhibited/hyperpolarized the great majority (81%) of non-serotonergic neurons recorded extra- and intracellularly in the DRN; the ENK effect reversed polarity at -99 +/- 9 mV, close to the potassium reversal potential.	Potassium	232-241	proenkephalin	Rattus norvegicus	39-42
9175891-8	1997	Consistent with the reduction in PSCs, ENK inhibited/hyperpolarized the great majority (81%) of non-serotonergic neurons recorded extra- and intracellularly in the DRN; the ENK effect reversed polarity at -99 +/- 9 mV, close to the potassium reversal potential.	Potassium	232-241	proenkephalin	Rattus norvegicus	173-176
9175891-9	1997	In contrast, ENK inhibited/hyperpolarized only 28% of serotonergic neurons; in the affected cells, the ENK effect, blocked by CTOP, had its reversal potential shifted with change of extracellular potassium in agreement with the value predicted by the Nernst equation for a potassium conductance; serotonin occluded the ENK inhibition.	Potassium	196-205	proenkephalin	Rattus norvegicus	13-16
9175891-9	1997	In contrast, ENK inhibited/hyperpolarized only 28% of serotonergic neurons; in the affected cells, the ENK effect, blocked by CTOP, had its reversal potential shifted with change of extracellular potassium in agreement with the value predicted by the Nernst equation for a potassium conductance; serotonin occluded the ENK inhibition.	Potassium	196-205	proenkephalin	Rattus norvegicus	103-106
9175891-9	1997	In contrast, ENK inhibited/hyperpolarized only 28% of serotonergic neurons; in the affected cells, the ENK effect, blocked by CTOP, had its reversal potential shifted with change of extracellular potassium in agreement with the value predicted by the Nernst equation for a potassium conductance; serotonin occluded the ENK inhibition.	Potassium	196-205	proenkephalin	Rattus norvegicus	103-106
9175891-9	1997	In contrast, ENK inhibited/hyperpolarized only 28% of serotonergic neurons; in the affected cells, the ENK effect, blocked by CTOP, had its reversal potential shifted with change of extracellular potassium in agreement with the value predicted by the Nernst equation for a potassium conductance; serotonin occluded the ENK inhibition.	Potassium	273-282	proenkephalin	Rattus norvegicus	13-16
9175891-9	1997	In contrast, ENK inhibited/hyperpolarized only 28% of serotonergic neurons; in the affected cells, the ENK effect, blocked by CTOP, had its reversal potential shifted with change of extracellular potassium in agreement with the value predicted by the Nernst equation for a potassium conductance; serotonin occluded the ENK inhibition.	Potassium	273-282	proenkephalin	Rattus norvegicus	103-106
9175891-9	1997	In contrast, ENK inhibited/hyperpolarized only 28% of serotonergic neurons; in the affected cells, the ENK effect, blocked by CTOP, had its reversal potential shifted with change of extracellular potassium in agreement with the value predicted by the Nernst equation for a potassium conductance; serotonin occluded the ENK inhibition.	Potassium	273-282	proenkephalin	Rattus norvegicus	103-106
9092603-11	1997	Thus, the effects of cesium on CA1 synchronization and synaptic plasticity appear to be mediated predominantly by blockade of glial voltage-dependent potassium uptake.	Potassium	150-159	carbonic anhydrase 1	Homo sapiens	31-34
9128206-8	1997	Plasma potassium concentration negatively correlated with SBP (r = -0.48, P < .01) and urinary sodium/potassium ratio also correlated inversely with urinary OLC excretion (r = -0.55, P < .01).	Potassium	7-16	spermine binding protein	Rattus norvegicus	58-61
9198848-1	1997	Potassium sparing diuretics in combination with thiazides represent a therapeutical enrichment if applied correctly that is with respect to contraindications, interactions (especially with ACE-inhibitors and AT1-antagonists) and to pharmacokinetic properties.	Potassium	0-9	angiotensin I converting enzyme	Homo sapiens	189-192
9251765-2	1997	Intraperitoneal (ip) injection of alpha-MSH (3 and 9.6 nmol) induced a significant increase in urinary sodium, potassium and water excretion.	Potassium	111-120	proopiomelanocortin	Homo sapiens	34-43
9198848-1	1997	Potassium sparing diuretics in combination with thiazides represent a therapeutical enrichment if applied correctly that is with respect to contraindications, interactions (especially with ACE-inhibitors and AT1-antagonists) and to pharmacokinetic properties.	Potassium	0-9	angiotensin II receptor type 1	Homo sapiens	208-211
9060831-4	1997	Immunostaining for MR was detected in 94 +/- 7% KS cells with spindle morphology.	Potassium	48-50	mannose receptor C-type 1	Homo sapiens	19-21
9098556-0	1997	Neuropeptide Y and [Leu31,Pro34]neuropeptide Y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat.	Potassium	58-67	neuropeptide Y	Rattus norvegicus	0-14
9098556-0	1997	Neuropeptide Y and [Leu31,Pro34]neuropeptide Y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat.	Potassium	58-67	neuropeptide Y	Rattus norvegicus	32-46
9098556-1	1997	This microdialysis study investigated the effects of NPY and the Y1 selective agonist [Leu31, Pro34]NPY on basal and potassium-stimulated noradrenaline release in the PVN of 18-month-old anaesthetised male Sprague-Dawley rats.	Potassium	117-126	neuropeptide Y	Rattus norvegicus	100-103
9098556-7	1997	Thus, in 18-month-old animals with reduced endogenous hypothalamic NPY content, administration of NPY or [Leu31, Pro34]NPY increased potassium-induced noradrenaline release to levels seen in 3-month-old rats.	Potassium	133-142	neuropeptide Y	Rattus norvegicus	98-101
9098556-7	1997	Thus, in 18-month-old animals with reduced endogenous hypothalamic NPY content, administration of NPY or [Leu31, Pro34]NPY increased potassium-induced noradrenaline release to levels seen in 3-month-old rats.	Potassium	133-142	neuropeptide Y	Rattus norvegicus	98-101
9107436-5	1997	Serum triglyceride was higher and potassium was lower in the drinkers with high serum GGT, and were normalized during alcohol moderation.	Potassium	34-43	gamma-glutamyltransferase 1	Homo sapiens	86-89
9164118-1	1997	Thallium-201 chloride (201Tl) kinetics, may be affected by serum insulin levels like potassium kinetics.	Potassium	85-94	insulin	Homo sapiens	65-72
9212648-3	1997	This article suggests that the initial dural damage caused by trauma results in minor bleeding, which in turn causes a raised potassium ion concentration in the hemolytic fluid, which may also cause depolarization and elevated AChE in the dura.	Potassium	126-135	acetylcholinesterase (Cartwright blood group)	Homo sapiens	227-231
9085573-1	1997	Sos1 is an Arabidopsis thaliana mutant with > 20 times higher sensitivity toward Na+ inhibition due to a defective high-affinity potassium-uptake system.	Potassium	132-141	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	0-4
9085573-4	1997	When assayed at 20 mM external NaCl, sos1 seedlings pretreated with low potassium have 32% lower Na+ uptake than the wild type.	Potassium	72-81	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	37-41
9087676-6	1997	We conclude that h-leptin may function as a potassium-sparing diuretic/natriuretic factor.	Potassium	44-53	leptin	Rattus norvegicus	19-25
9081107-2	1997	(2) Does the addition of insulin (glucose-insulin-potassium solution) provide additional effects to those of an amino acid infusion?	Potassium	50-59	insulin	Homo sapiens	25-32
9090882-11	1997	Deprivation of nitrogen, phosphorus, potassium, and sulfur changed spatial expression as well as the expression level of StPT1.	Potassium	37-46	inorganic phosphate transporter	Solanum tuberosum	121-126
9106510-9	1997	Induction of the TPSI1 gene appears to be a response specific to Pi starvation since it is not affected by starvation of other nutrients (nitrogen, potassium and iron).	Potassium	148-157	TPSI1	Solanum lycopersicum	17-22
9040630-3	1997	In 15 patients, glucose-insulin-potassium solution (30% dextrose in water; K+, 80 mEq/L: regular insulin, 50 units) was given intravenously at 1 ml/kg per hour after induction of anesthesia and administration continued for 12 hours after aortic unclamping.	Potassium	32-41	insulin	Homo sapiens	24-31
8988947-6	1997	Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP.	Potassium	126-135	selenium binding protein 1	Homo sapiens	139-142
8999849-0	1997	Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange.	Potassium	46-55	solute carrier family 1 member 2	Homo sapiens	94-99
8988947-6	1997	Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP.	Potassium	126-135	D-box binding PAR bZIP transcription factor	Homo sapiens	147-150
8988947-6	1997	Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP.	Potassium	179-188	selenium binding protein 1	Homo sapiens	192-195
8988947-6	1997	Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP.	Potassium	179-188	D-box binding PAR bZIP transcription factor	Homo sapiens	200-203
9547670-8	1997	We conclude that KS cells express a functional IL-4R and this receptor could serve as a target for novel therapy with agents such as DAB389-IL-4.	Potassium	17-19	interleukin 4 receptor	Homo sapiens	47-52
9227836-2	1997	The present study examined the activation of CaM-kinase II (calcium/calmodulin-dependent protein kinase II) in CA1 and CA3 areas after glutamate or potassium stimulation.	Potassium	148-157	carbonic anhydrase 1	Rattus norvegicus	111-114
9227836-2	1997	The present study examined the activation of CaM-kinase II (calcium/calmodulin-dependent protein kinase II) in CA1 and CA3 areas after glutamate or potassium stimulation.	Potassium	148-157	carbonic anhydrase 3	Rattus norvegicus	119-122
9547670-8	1997	We conclude that KS cells express a functional IL-4R and this receptor could serve as a target for novel therapy with agents such as DAB389-IL-4.	Potassium	17-19	interleukin 4	Homo sapiens	47-51
8978711-5	1997	In low-potassium cultures, the neurotrophic effect of BDNF approached that found in high-potassium cultures but was much more robust than that of NT-3.	Potassium	7-16	brain-derived neurotrophic factor	Rattus norvegicus	54-58
8978711-5	1997	In low-potassium cultures, the neurotrophic effect of BDNF approached that found in high-potassium cultures but was much more robust than that of NT-3.	Potassium	89-98	brain-derived neurotrophic factor	Rattus norvegicus	54-58
8978711-2	1997	A high-potassium culturing condition has been reported to increase the intracellular calcium concentration ([Ca2+]i) and the expression of brain-derived neurotrophic factor (BDNF), which in turn induces the expression of neurotrophin-3 (NT-3) in these neurons.	Potassium	7-16	brain-derived neurotrophic factor	Rattus norvegicus	139-172
8978711-10	1997	Because nitroprusside neurotoxicity is less robust in high-potassium cultures, high-potassium-induced BDNF expression and subsequent NT-3 expression may participate in its neuroprotection and neurotrophism in these cultures.	Potassium	84-93	brain-derived neurotrophic factor	Rattus norvegicus	102-106
8978711-2	1997	A high-potassium culturing condition has been reported to increase the intracellular calcium concentration ([Ca2+]i) and the expression of brain-derived neurotrophic factor (BDNF), which in turn induces the expression of neurotrophin-3 (NT-3) in these neurons.	Potassium	7-16	brain-derived neurotrophic factor	Rattus norvegicus	174-178
8978711-10	1997	Because nitroprusside neurotoxicity is less robust in high-potassium cultures, high-potassium-induced BDNF expression and subsequent NT-3 expression may participate in its neuroprotection and neurotrophism in these cultures.	Potassium	84-93	neurotrophin 3	Rattus norvegicus	133-137
8978711-2	1997	A high-potassium culturing condition has been reported to increase the intracellular calcium concentration ([Ca2+]i) and the expression of brain-derived neurotrophic factor (BDNF), which in turn induces the expression of neurotrophin-3 (NT-3) in these neurons.	Potassium	7-16	neurotrophin 3	Rattus norvegicus	221-235
8978711-2	1997	A high-potassium culturing condition has been reported to increase the intracellular calcium concentration ([Ca2+]i) and the expression of brain-derived neurotrophic factor (BDNF), which in turn induces the expression of neurotrophin-3 (NT-3) in these neurons.	Potassium	7-16	neurotrophin 3	Rattus norvegicus	237-241
9398028-6	1997	A similar decline in reabsorption was seen with intratubular application of Ang 1-7 in a concentration of 10(-12) or 10(-10) M. In contrast, intratubular application of Ang 1-7 in a concentration of 10(-8) M increased fluid, potassium and sodium reabsorption in that nephron segment by 11, 9 and 3%, respectively.	Potassium	225-234	angiogenin	Rattus norvegicus	169-176
8978727-5	1997	GAD-modified neurons released both glutamate and GABA into the surrounding media before and after potassium-induced stimulation, but only the release of glutamate was sensitive to potassium stimulation.	Potassium	98-107	glutamate decarboxylase 1	Homo sapiens	0-3
8978727-5	1997	GAD-modified neurons released both glutamate and GABA into the surrounding media before and after potassium-induced stimulation, but only the release of glutamate was sensitive to potassium stimulation.	Potassium	180-189	glutamate decarboxylase 1	Homo sapiens	0-3
9532579-3	1997	Using patch clamp methods, we studied neurotrophin regulation of voltage-gated sodium, calcium, and potassium currents in SK-N-SH neuroblastoma cells.	Potassium	100-109	brain derived neurotrophic factor	Homo sapiens	38-50
8978385-0	1997	Methionine sulfoximine, a glutamine synthetase inhibitor, attenuates increased extracellular potassium activity during acute hyperammonemia.	Potassium	93-102	glutamate-ammonia ligase	Rattus norvegicus	26-46
9003357-10	1996	The Ks of BB LPH was not different between experimental treatment groups (on average 0.037%/min).	Potassium	4-6	lactase phlorizin hydrolase	Sus scrofa	13-16
9016353-6	1997	Glutamate evoked pertussis toxin-sensitive potassium currents in Xenopus laevis oocytes coexpressing mGluR8 and G protein-coupled inwardly rectifying potassium channels.	Potassium	43-52	glutamate receptor, metabotropic 8	Mus musculus	101-107
8989127-5	1996	Urine volume and urine sodium excretion increased significantly during hBNP infusion when compared with placebo infusion (90 +/- 38 versus 67 +/- 27 mL/h and 2.6 +/- 2.4 versus 1.4 +/- 1.2 mEq/h, respectively, both P < .05 versus placebo), whereas creatinine clearance and urinary potassium excretion did not change.	Potassium	284-293	natriuretic peptide B	Homo sapiens	71-75
9210182-7	1997	Thus, calcitonin inhibition of sodium/potassium transport through synaptic membranes supports a regulatory role of this peptide on neurotransmission.	Potassium	38-47	calcitonin-related polypeptide alpha	Rattus norvegicus	6-16
9000551-3	1997	Under some circumstances when afferent blood supply is compromised, particularly beyond a renal arterial stenosis, use of angiotensin-converting enzyme (ACE) inhibitors can lead to decrements of glomerular filtration rate (GFR) and impaired potassium excretion, which clinicians should be prepared to identify and manage.	Potassium	241-250	angiotensin I converting enzyme	Homo sapiens	153-156
8973193-3	1996	From difference visible spectroscopy experiments using microsomes of yeast expressing various human P450s, 1 selectively interacts only with CYP 2C9 with the appearance of a peak at 429 nm as expected for the formation of a P450 Fe(III)-nitrogenous ligand complex (Ks = 0.4 +/- 0.1 microM).	Potassium	265-267	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	141-148
8968586-1	1996	Recovery from C-type inactivation of Kv1.3 can be accelerated by the binding of extracellular potassium to the channel in a voltage-dependent fashion.	Potassium	94-103	potassium voltage-gated channel subfamily A member 3	Homo sapiens	37-42
8987838-3	1996	The present study examined the ability of GDNF to prevent METH-induced reductions in potassium-evoked overflow of DA, and DA and 5-HT content, in striatum.	Potassium	85-94	glial cell derived neurotrophic factor	Rattus norvegicus	42-46
8958576-3	1996	The possibility that elevation of cAMP also alters potassium-evoked release of CCK from rat brain slices incubated in vitro was also investigated.	Potassium	51-60	cholecystokinin	Rattus norvegicus	79-82
8968552-17	1996	PD155080, in the presence of endothelin-1 and acetylcholine, increased the inward component of the "steady state" potassium current to -1030 +/- 210 pA from a control value of -804 +/- 224 pA at a step potential of -100 mV.	Potassium	114-123	endothelin-1	Oryctolagus cuniculus	29-41
8968552-19	1996	Unlike PD155080, the ETB receptor-selective antagonist, RES-701 (1 microM), only prevented (P < 0.05) the inhibitory effect of endothelin-1 on the inward component of the IK(ACh); at -100 mV, RES-701, in the presence of endothelin-1 and acetylcholine, increased the "steady state" potassium current to -913 +/- 137 pA from -733 +/- 116 pA.	Potassium	284-293	endothelin-1	Oryctolagus cuniculus	130-142
9113130-5	1996	Furthermore, not only elevated potassium ions, but D-amphetamine as well as GBR12909, all produced significant increases in the percentage spontaneous release of acetylcholinesterase.	Potassium	31-40	acetylcholinesterase	Rattus norvegicus	162-182
8982509-0	1996	Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro.	Potassium	34-43	opioid related nociceptin receptor 1	Rattus norvegicus	0-19
8985898-11	1996	The tachykinin substance P could reduce inward and outward rectification in the dorsal cells, the effect on outward rectification only being seen when potassium conductances were blocked by tetraethylammonium (TEA).	Potassium	151-160	tachykinin precursor 1	Homo sapiens	15-26
8982171-2	1996	Pharmacological evidence from the inner ear suggests that isk mediates potassium secretion into the endolymph.	Potassium	71-80	potassium voltage-gated channel, Isk-related subfamily, member 1	Mus musculus	58-61
8977477-14	1996	CONCLUSIONS: The IL application of insulin dilates potassium-contracted pig retinal arteries.	Potassium	51-60	insulin	Sus scrofa	35-42
8968339-5	1996	Two-fold increases in potassium-evoked DA overflow were seen throughout the striatum by means of high-speed chronoamperometry 3 weeks after GDNF injection.	Potassium	22-31	glial cell derived neurotrophic factor	Rattus norvegicus	140-144
8947314-4	1996	Previously, we observed that EtOH and NGF modulate intracellular Ca2+ levels [Ca2+]i) in unstimulated and high potassium stimulated (30 mM KCl) cultured rat embryonic day 21 (E21) MS neurons (Webb et al., Brain Res 701:61-74, 1995).	Potassium	111-120	nerve growth factor	Rattus norvegicus	38-41
8944674-7	1996	GH significantly increased Ks in skeletal muscle and jejunal muscularis, IGF-I significantly increased Ks in jejunal mucosa and muscularis, and neither GH nor IGF-I altered Ks in liver.	Potassium	103-105	insulin-like growth factor 1	Rattus norvegicus	73-78
8944674-7	1996	GH significantly increased Ks in skeletal muscle and jejunal muscularis, IGF-I significantly increased Ks in jejunal mucosa and muscularis, and neither GH nor IGF-I altered Ks in liver.	Potassium	103-105	insulin-like growth factor 1	Rattus norvegicus	73-78
8969884-7	1996	In contrast, both IGF-1 (10 ng/ml) and potassium ions (12 mM) increased the levels of AT1 receptor mRNA.	Potassium	39-48	angiotensin II receptor type 1	Bos taurus	86-89
8900282-0	1996	K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current.	Potassium	69-78	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	0-8
8923010-2	1996	beta-Cell ATP-sensitive potassium currents can be reconstituted by coexpression of the inward rectifier Kir6.2 and the sulfonylurea receptor (SUR), a member of the ATP-binding cassette superfamily.	Potassium	24-33	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	104-110
8923010-2	1996	beta-Cell ATP-sensitive potassium currents can be reconstituted by coexpression of the inward rectifier Kir6.2 and the sulfonylurea receptor (SUR), a member of the ATP-binding cassette superfamily.	Potassium	24-33	ATP binding cassette subfamily C member 8	Homo sapiens	119-140
8923010-2	1996	beta-Cell ATP-sensitive potassium currents can be reconstituted by coexpression of the inward rectifier Kir6.2 and the sulfonylurea receptor (SUR), a member of the ATP-binding cassette superfamily.	Potassium	24-33	ATP binding cassette subfamily C member 8	Homo sapiens	142-145
9346691-0	1996	Glucose and potassium metabolic responses to insulin during liver transplantation.	Potassium	12-21	insulin	Homo sapiens	45-52
8910791-2	1996	We demonstrate that a depolarizing pulse of extracellular potassium can prime neurons to become responsive to basic fibroblast growth factor (bFGF), even when the pulse is brief and occurs prior to addition of bFGF.	Potassium	58-67	fibroblast growth factor 2	Gallus gallus	110-140
8910791-2	1996	We demonstrate that a depolarizing pulse of extracellular potassium can prime neurons to become responsive to basic fibroblast growth factor (bFGF), even when the pulse is brief and occurs prior to addition of bFGF.	Potassium	58-67	fibroblast growth factor 2	Gallus gallus	142-146
8910791-2	1996	We demonstrate that a depolarizing pulse of extracellular potassium can prime neurons to become responsive to basic fibroblast growth factor (bFGF), even when the pulse is brief and occurs prior to addition of bFGF.	Potassium	58-67	fibroblast growth factor 2	Gallus gallus	210-214
9346691-1	1996	Insulin regulates glucose and potassium metabolism by acting differently upon peripheral tissues (e.g., skeletal muscle) and the splanchnic bed, including the liver.	Potassium	30-39	insulin	Homo sapiens	0-7
9346691-5	1996	The present study evaluated the role of the liver in maximal insulin responsiveness of whole-body glucose and potassium metabolism, using a hyperinsulinemic clamp technique, to identify the mechanism(s) underlying post-reperfusion hyperglycemia and intraoperative hyperkalemia.	Potassium	110-119	insulin	Homo sapiens	61-68
9346691-10	1996	Insulin-stimulated exogenous glucose and potassium uptakes were determined in protocol 2 before skin incision and during the dissection, anhepatic, and neohepatic stages.	Potassium	41-50	insulin	Homo sapiens	0-7
9346691-19	1996	Insulin-stimulated potassium uptake, in mEq .	Potassium	19-28	insulin	Homo sapiens	0-7
9346691-25	1996	The liver, even with end-stage disease, accounts for approximately 70% of insulin-stimulated potassium uptake.	Potassium	93-102	insulin	Homo sapiens	74-81
8810295-11	1996	Analysis of PIP2-stimulated PI hydrolysis by a dual substrate binding model of catalysis revealed that the micellar dissociation constant (Ks) of PLCdelta1 for the PI/PS/PC vesicles was reduced from 558 microM to 53 microM, and the interfacial Michaelis constant (Km) was reduced from 0.21 to 0.06 by PIP2.	Potassium	139-141	phospholipase C delta 1	Homo sapiens	146-155
8815916-0	1996	GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons.	Potassium	45-54	carbonic anhydrase 3	Homo sapiens	90-93
8815916-1	1996	GABA and the GABAB receptor agonist baclofen activated a potassium conductance in acutely dissociated hippocampal CA3 neurons.	Potassium	57-66	carbonic anhydrase 3	Homo sapiens	114-117
8798711-8	1996	Kinetic analysis of PLCdelta1-catalyzed PIP2 hydrolysis revealed that the micellar dissociation constant Ks and interfacial Michaelis constant Km were similar in the native, R549K, and R549H enzymes; but the specific activity at the saturated substrate mole fraction and infinite level of substrate (Vmax) of the R549H mutant were reduced by a factor of 15.	Potassium	105-107	phospholipase C delta 1	Homo sapiens	20-29
8873679-8	1996	The SCN5A mutations result in defective sodium channel inactivation, whereas HERG mutations result in decreased outward potassium current.	Potassium	120-129	potassium voltage-gated channel subfamily H member 2	Homo sapiens	77-81
8855942-6	1996	Treatment of the cells either by saccharose hypertonic shock or by potassium depletion, in order to block clathrin-coated vesicle formation, completely inhibited HDL3 internalization, as also observed with LDL.	Potassium	67-76	HDL3	Homo sapiens	162-166
8899894-0	1996	Whole cell patch recordings from forebrain slices demonstrate angiotensin II inhibits potassium currents in subfornical organ neurons.	Potassium	86-95	angiotensinogen	Homo sapiens	62-76
8810295-11	1996	Analysis of PIP2-stimulated PI hydrolysis by a dual substrate binding model of catalysis revealed that the micellar dissociation constant (Ks) of PLCdelta1 for the PI/PS/PC vesicles was reduced from 558 microM to 53 microM, and the interfacial Michaelis constant (Km) was reduced from 0.21 to 0.06 by PIP2.	Potassium	139-141	surfactant protein C	Homo sapiens	167-172
8880194-6	1996	After adjusting for prognostic factors, the most important of which is the median CD4+ T-lymphocyte count at presentation the survival of patients with KS is improving as the AIDS epidemic matures.	Potassium	152-154	CD4 molecule	Homo sapiens	82-85
8896735-0	1996	Development of low potassium solution (EP4 solution) for long-term preservation of a lung transplant: evaluation in primate and murine lung transplant model.	Potassium	19-28	prostaglandin E receptor 4 (subtype EP4)	Mus musculus	39-42
8828493-2	1996	Each of these two pharmacological agents completely inhibited the initiation of CYP11B2 expression and aldosterone biosynthesis in response to a high extracellular potassium concentration (18 mM).	Potassium	164-173	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	80-87
8828493-3	1996	They also suppressed the potassium-induced increases in CYP11B1, CYP11A1, and CYP21A1 messenger RNA levels.	Potassium	25-34	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	56-63
8828493-3	1996	They also suppressed the potassium-induced increases in CYP11B1, CYP11A1, and CYP21A1 messenger RNA levels.	Potassium	25-34	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	65-72
8828493-3	1996	They also suppressed the potassium-induced increases in CYP11B1, CYP11A1, and CYP21A1 messenger RNA levels.	Potassium	25-34	cytochrome P450, family 21, subfamily a, polypeptide 1	Rattus norvegicus	78-85
8840939-2	1996	Whereas insulin and albuterol are effective in lowering plasma potassium acutely, bicarbonate by itself is not.	Potassium	63-72	insulin	Homo sapiens	8-15
8840939-3	1996	Bicarbonate administration may, however, potentiate the effects of insulin and albuterol on plasma potassium.	Potassium	99-108	insulin	Homo sapiens	67-74
8840939-7	1996	Intravenous insulin decreased plasma potassium by a similar degree when given in conjunction with bicarbonate or saline (-0.81 +/- 0.05 mmol/L v -0.85 +/- 0.06 mmol/L at 60 minutes; P = 0.65).	Potassium	37-46	insulin	Homo sapiens	12-19
8887769-10	1996	Both 38 and 44 kDa MBP kinase activities increased significantly during contractions induced by 10 microM acetylcholine, 0.1 microM neurokinin A and 70 mM potassium.	Potassium	155-164	myelin basic protein	Canis lupus familiaris	19-22
8795623-1	1996	In hippocampal neurons, a slowly inactivating aminopyridine-sensitive transient potassium current, D-current, influences the time course of action potential repolarization and therefore activity-dependent Ca2+ entry.	Potassium	80-89	carbonic anhydrase 2	Rattus norvegicus	205-208
8902992-6	1996	A strong inverse correlation was seen between plasma plasminogen activator inhibitor-1 (PAI-1) activity and Ks (r = -0.603, p < 0.001) or fiber mass-length ratio (r = -0.565, p < 0.001) in the patient group.	Potassium	108-110	serpin family E member 1	Homo sapiens	53-86
8902992-6	1996	A strong inverse correlation was seen between plasma plasminogen activator inhibitor-1 (PAI-1) activity and Ks (r = -0.603, p < 0.001) or fiber mass-length ratio (r = -0.565, p < 0.001) in the patient group.	Potassium	108-110	serpin family E member 1	Homo sapiens	88-93
8756540-4	1996	Because the synthesis of testosterone in the potassium-deficient mice was stimulated by exogenous LH, hCG, or GnRH, one can conclude that alteration of the transcellular potassium gradient could affect the regulation of the hypothalamo-hypophyseal-testicular axis by affecting the pulsatile release of GnRH.	Potassium	45-54	gonadotropin releasing hormone 1	Mus musculus	110-114
8884981-3	1996	Results showed that in the submaxillary gland, ANF increased sodium and decreased potassium excretion when salivation was stimulated by methacholine (MC) or substance P (SP).	Potassium	82-91	natriuretic peptide A	Rattus norvegicus	47-50
8884981-5	1996	On the other hand, in the parotid gland, ANF increased both sodium and potassium excretion when salivation was induced either by MC or SP but did not modify electrolyte output in MX induced salivary secretion.	Potassium	71-80	natriuretic peptide A	Rattus norvegicus	41-44
8790040-2	1996	BACKGROUND: Many members of families with inherited long-QT (LQT) syndrome have mutations in HERG, a gene encoding a cardiac potassium channel that is modulated by extracellular potassium.	Potassium	125-134	potassium voltage-gated channel subfamily H member 2	Homo sapiens	93-97
8797398-10	1996	Both beta 2-agonists caused a decrease in serum potassium level that was significantly greater in the fenoterol (0.23 +/- 0.04 mmol/L) than in the salbutamol (0.06 +/- 0.03 mmol/L) group (p = 0.0002).	Potassium	48-57	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	5-11
8756540-4	1996	Because the synthesis of testosterone in the potassium-deficient mice was stimulated by exogenous LH, hCG, or GnRH, one can conclude that alteration of the transcellular potassium gradient could affect the regulation of the hypothalamo-hypophyseal-testicular axis by affecting the pulsatile release of GnRH.	Potassium	170-179	gonadotropin releasing hormone 1	Mus musculus	302-306
8843704-11	1996	In summary, CHIF mRNA is selectively expressed in the medullary collecting duct of the kidney and in the epithelium of the distal colon; its expression varies differently in these two target tissues after alterations in corticosteroid status, potassium depletion, and metabolic acidosis.	Potassium	243-252	FXYD domain-containing ion transport regulator 4	Rattus norvegicus	12-16
8809065-3	1996	sPLA2 immunoreactive with anti-(type II sPLA2) antibody was released from synaptosomes in response to depolarization evoked by a high concentration of potassium in the presence of Ca2+.	Potassium	151-160	phospholipase A2 group IIA	Rattus norvegicus	0-5
8809065-3	1996	sPLA2 immunoreactive with anti-(type II sPLA2) antibody was released from synaptosomes in response to depolarization evoked by a high concentration of potassium in the presence of Ca2+.	Potassium	151-160	phospholipase A2 group IIA	Rattus norvegicus	40-45
8809065-7	1996	When neuronally differentiated PC12 cells were stimulated with carbamylcholine or potassium, sPLA2 was released into the medium and reached a maximal approximately 40% release by 15 min.	Potassium	82-91	phospholipase A2 group IIA	Rattus norvegicus	93-98
8886404-16	1996	The TAPP-induced diuretic action, increased sodium/potassium excretion and elevated urinary cyclic GMP levels were also reversed by anti-ANF antibodies.	Potassium	51-60	natriuretic peptide A	Rattus norvegicus	137-140
8756540-4	1996	Because the synthesis of testosterone in the potassium-deficient mice was stimulated by exogenous LH, hCG, or GnRH, one can conclude that alteration of the transcellular potassium gradient could affect the regulation of the hypothalamo-hypophyseal-testicular axis by affecting the pulsatile release of GnRH.	Potassium	45-54	gonadotropin releasing hormone 1	Mus musculus	302-306
8877285-11	1996	In addition, ET-1 transiently enhanced 86Rb(+)-efflux from 86Rb(+)-prelabelled islets both in the presence (p < 0.001) and in the absence (p < 0.001) of extracellular Ca2+ suggesting that ET-1 does not elicit insulin secretion by inhibition of the potassium permeability.	Potassium	254-263	endothelin 1	Mus musculus	13-17
8756540-4	1996	Because the synthesis of testosterone in the potassium-deficient mice was stimulated by exogenous LH, hCG, or GnRH, one can conclude that alteration of the transcellular potassium gradient could affect the regulation of the hypothalamo-hypophyseal-testicular axis by affecting the pulsatile release of GnRH.	Potassium	170-179	gonadotropin releasing hormone 1	Mus musculus	110-114
8902599-4	1996	The Michaelis-Menten constant (Ks) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.123 mM in the control system, and the MTX-treated systems showed a 10-35% decrease in this value.	Potassium	31-33	acetylcholinesterase	Camelus dromedarius	92-96
8889439-6	1996	Furthermore, insulin infusion increased forearm lactate release and potassium uptake.	Potassium	68-77	insulin	Homo sapiens	13-20
8872472-10	1996	These data confirm the role of KVLQT1 in the LQTS and suggest that mutant KVLQT1 proteins may exert a dominant negative effect on repolarizing potassium currents by forming multimers with normal potassium channel protein subunits, dramatically reducing the number of fully-functional KVLQT1 channels.	Potassium	143-152	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	74-80
8872472-10	1996	These data confirm the role of KVLQT1 in the LQTS and suggest that mutant KVLQT1 proteins may exert a dominant negative effect on repolarizing potassium currents by forming multimers with normal potassium channel protein subunits, dramatically reducing the number of fully-functional KVLQT1 channels.	Potassium	143-152	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	74-80
8872957-0	1996	Potassium depletion modulates aldose reductase mRNA in rat renal inner medulla.	Potassium	0-9	aldo-keto reductase family 1 member B1	Rattus norvegicus	30-46
8872957-9	1996	Data suggested that aldose reductase mRNA abundance was reduced in potassium depletion irrespective of medullary sodium content.	Potassium	67-76	aldo-keto reductase family 1 member B1	Rattus norvegicus	20-36
8973378-3	1996	When expressed in Xenopus oocytes, two of these clones (Kir4.1 and Kir2.3) gave rise to inwardly rectifying potassium currents.	Potassium	108-117	potassium inwardly rectifying channel subfamily J member 10 S homeolog	Xenopus laevis	56-62
8872957-11	1996	Our finding constitutes the first demonstration of the relationship between a potassium deficiency and the abundance of aldose reductase mRNA, an osmoregulatory protein in the kidney.	Potassium	78-87	aldo-keto reductase family 1 member B1	Rattus norvegicus	120-136
8768839-9	1996	These results suggest a selective modulation by vitamin D of the renal response to PTH; 1,25-(OH)2D3 facilitates PTH-induced calcium and sodium reabsorption, but does not influence PTH-induced cAMP excretion; phosphorus, potassium, and bicarbonate tubular transport, or 1 alpha-hydroxylation of 25-hydroxyvitamin D3.	Potassium	221-230	parathyroid hormone	Homo sapiens	83-86
8799178-7	1996	The coexpression of hslo-beta mRNA together with hslo-alpha subunits in either Xenopus oocytes or stably transfected HEK 293 cells give rise to Ca(2+)-activated potassium currents with a much increased calcium and/or voltage sensitivity.	Potassium	161-170	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	20-29
8866349-3	1996	In the present study, the whole-cell configuration of the patch-clamp technique was used to investigate the modulation of potassium conductances by calcium and hCG, in the Leydig cells from mature rat testis.	Potassium	122-131	chorionic gonadotropin subunit beta 5	Homo sapiens	160-163
8842207-1	1996	Potassium conduction through unblocked inwardly rectifying (IRK1, Kir2.1) potassium channels was measured in inside-out-patches from Xenopus oocytes, after removal of polyamine-induced strong inward rectification.	Potassium	0-9	potassium inwardly rectifying channel subfamily J member 2 L homeolog	Xenopus laevis	60-64
8973378-3	1996	When expressed in Xenopus oocytes, two of these clones (Kir4.1 and Kir2.3) gave rise to inwardly rectifying potassium currents.	Potassium	108-117	potassium inwardly rectifying channel subfamily J member 4 S homeolog	Xenopus laevis	67-73
8842207-1	1996	Potassium conduction through unblocked inwardly rectifying (IRK1, Kir2.1) potassium channels was measured in inside-out-patches from Xenopus oocytes, after removal of polyamine-induced strong inward rectification.	Potassium	0-9	potassium inwardly rectifying channel subfamily J member 2 L homeolog	Xenopus laevis	66-72
8764657-0	1996	Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species.	Potassium	0-9	caspase 1	Homo sapiens	132-135
8764613-0	1996	Endothelin-1 increases arachidonic acid release in C6 glioma cells through a potassium-modulated influx of calcium.	Potassium	77-86	endothelin 1	Homo sapiens	0-12
8809828-0	1996	Complement factor C5a and epidermal growth factor trigger the activation of outward potassium currents in cultured murine microglia.	Potassium	84-93	hemolytic complement	Mus musculus	18-21
8809828-0	1996	Complement factor C5a and epidermal growth factor trigger the activation of outward potassium currents in cultured murine microglia.	Potassium	84-93	epidermal growth factor	Mus musculus	26-49
8871202-0	1996	Inhibition of transient potassium current in cultured and acutely dissociated mouse hippocampal neurons by GABAA receptor activation.	Potassium	24-33	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	107-112
9070382-2	1996	The benefits of ACE inhibition include not only a reduction in blood pressure but also improved insulin responsiveness, prevention of potassium loss, diminished myocardial oxygen demand, suppression of catecholamines, and interaction with bradykinin and prostaglandins.	Potassium	134-143	angiotensin I converting enzyme	Homo sapiens	16-19
8674891-4	1996	SSPG correlated with the percentage decrease of branched chain amino acids, free fatty acids, and serum potassium during the insulin sensitivity test.	Potassium	104-113	insulin	Homo sapiens	125-132
8670799-2	1996	Co-injection of mRNAs encoding Kir 4.1 and Kir 5.1 resulted in potassium currents that (i) were much larger than those seen from expression of Kir 4.1 alone, (ii) increased rather than decreased during several seconds at strongly negative potentials and (iii) had an underlying unitary conductance of 43 pS rather than the 12 pS seen with Kir 4.1 alone.	Potassium	63-72	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	31-38
8670799-2	1996	Co-injection of mRNAs encoding Kir 4.1 and Kir 5.1 resulted in potassium currents that (i) were much larger than those seen from expression of Kir 4.1 alone, (ii) increased rather than decreased during several seconds at strongly negative potentials and (iii) had an underlying unitary conductance of 43 pS rather than the 12 pS seen with Kir 4.1 alone.	Potassium	63-72	potassium inwardly-rectifying channel, subfamily J, member 16	Rattus norvegicus	43-50
8813709-4	1996	The Michaelis-Menten constant (Ks) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.13 mM in the control system, a value decreased by 30-61% in the MTX treated systems.	Potassium	31-33	acetylcholinesterase (Cartwright blood group)	Homo sapiens	92-96
8641193-4	1996	The high potassium concentration also caused distinct increases in the levels of CYP11B1, CYP11A1, and CYP21A1 mRNA, comparable to those induced by ACTH.	Potassium	9-18	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	81-88
8641193-4	1996	The high potassium concentration also caused distinct increases in the levels of CYP11B1, CYP11A1, and CYP21A1 mRNA, comparable to those induced by ACTH.	Potassium	9-18	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	90-97
8641193-4	1996	The high potassium concentration also caused distinct increases in the levels of CYP11B1, CYP11A1, and CYP21A1 mRNA, comparable to those induced by ACTH.	Potassium	9-18	cytochrome P450, family 21, subfamily a, polypeptide 1	Rattus norvegicus	103-110
8641193-7	1996	According to these results, potassium initiates CYP11B2 biosynthesis most likely at the level of transcription or by increasing mRNA stability.	Potassium	28-37	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	48-55
8789768-2	1996	Recently the beta-2 stimulatory drug salbutamol has been shown to be an effective agent to treat hyperkalaemia by inducing a shift of potassium into the intracellular compartment.	Potassium	134-143	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	13-19
8756495-0	1996	Regulation of Arabidopsis thaliana (L.) Heynh Arginine decarboxylase by potassium deficiency stress.	Potassium	72-81	arginine decarboxylase 1	Arabidopsis thaliana	46-68
8756495-2	1996	ARGdc enzyme activity has been shown to be induced by many environmental factors, including potassium deficiency stress.	Potassium	92-101	arginine decarboxylase 1	Arabidopsis thaliana	0-5
8756495-3	1996	We investigated the mechanism for induction of ARGdc activity during potassium deficiency stress in Arabidopsis thaliana (L.) Heynh.	Potassium	69-78	arginine decarboxylase 1	Arabidopsis thaliana	47-52
8756495-4	1996	We show that A. thaliana responds to potassium deficiency stress by increasing ARGdc activity by up to 10-fold over unstressed plants with a corresponding increase in putrescine levels of up to 20-fold.	Potassium	37-46	arginine decarboxylase 1	Arabidopsis thaliana	79-84
8756495-8	1996	The increase in ARGdc enzyme activity due to potassium deficiency stress does not appear to involve changes in mRNA or protein abundance.	Potassium	45-54	arginine decarboxylase 1	Arabidopsis thaliana	16-21
8832156-4	1996	However, recently also the beta 2 stimulatory drug salbutamol has been shown to be an effective agent to treat hyperkalemia by inducing a shift of potassium into the intracellular compartment.	Potassium	147-156	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	27-33
9139127-1	1996	Complementary DNAs involved in potassium transport in Schizosaccharomyces pombe were selected by complementation of defective K+ uptake in a trk1 trk2 mutant of Saccharomyces cerevisiae.	Potassium	31-40	Trk1p	Saccharomyces cerevisiae S288C	141-145
9139127-1	1996	Complementary DNAs involved in potassium transport in Schizosaccharomyces pombe were selected by complementation of defective K+ uptake in a trk1 trk2 mutant of Saccharomyces cerevisiae.	Potassium	31-40	Trk2p	Saccharomyces cerevisiae S288C	146-150
8662851-3	1996	Phorbol 12-myristate 13-acetate treatment enhanced high potassium-induced [3H]-norepinephrine release, and a 28-kDa protein recognized by an anti-SNAP-25 antibody was phosphorylated on Ser residues.	Potassium	56-65	synaptosome associated protein 25	Rattus norvegicus	146-153
8760660-6	1996	The prevention of the secondary effects of diuretics and ACE inhibitors on renal function, serum sodium, potassium and magnesium concentrations, is based on an initial low dose prescription, the detection and correction of risk factors and strict clinical and biological surveillance.	Potassium	105-114	angiotensin I converting enzyme	Homo sapiens	57-60
8641193-1	1996	The effects of the extracellular potassium concentration on the expression of four steroidogenic cytochromes P-450 (CYP11B2, CYP11B1, CYP11A1, and CYP21A1) in cultured rat adrenal zona glomerulosa cells were studied by Northern blot analysis.	Potassium	33-42	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	116-123
8641193-1	1996	The effects of the extracellular potassium concentration on the expression of four steroidogenic cytochromes P-450 (CYP11B2, CYP11B1, CYP11A1, and CYP21A1) in cultured rat adrenal zona glomerulosa cells were studied by Northern blot analysis.	Potassium	33-42	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	125-132
8641193-1	1996	The effects of the extracellular potassium concentration on the expression of four steroidogenic cytochromes P-450 (CYP11B2, CYP11B1, CYP11A1, and CYP21A1) in cultured rat adrenal zona glomerulosa cells were studied by Northern blot analysis.	Potassium	33-42	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	134-141
8641193-1	1996	The effects of the extracellular potassium concentration on the expression of four steroidogenic cytochromes P-450 (CYP11B2, CYP11B1, CYP11A1, and CYP21A1) in cultured rat adrenal zona glomerulosa cells were studied by Northern blot analysis.	Potassium	33-42	cytochrome P450, family 21, subfamily a, polypeptide 1	Rattus norvegicus	147-154
8641193-2	1996	At a potassium concentration of 6.4 mM, the CYP11B2 messenger RNA (mRNA) level and aldosterone production were undetectable.	Potassium	5-14	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	44-51
8641193-3	1996	Upon increasing the potassium concentration to 18 mM, CYP11B2 mRNA and aldosterone production became measurable and reached a plateau within 4 days.	Potassium	20-29	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	54-61
8632147-1	1996	In bovine chromaffin cells forskolin, phorbol ester, or high potassium levels induce a rapid increase of c-fos, c-jun, and junB mRNA levels, which precede an induction of proenkephalin gene expression.	Potassium	61-70	Fos proto-oncogene, AP-1 transcription factor subunit	Bos taurus	107-110
8632147-1	1996	In bovine chromaffin cells forskolin, phorbol ester, or high potassium levels induce a rapid increase of c-fos, c-jun, and junB mRNA levels, which precede an induction of proenkephalin gene expression.	Potassium	61-70	JunB proto-oncogene, AP-1 transcription factor subunit	Bos taurus	123-127
8632147-1	1996	In bovine chromaffin cells forskolin, phorbol ester, or high potassium levels induce a rapid increase of c-fos, c-jun, and junB mRNA levels, which precede an induction of proenkephalin gene expression.	Potassium	61-70	proenkephalin	Bos taurus	171-184
8713674-2	1996	A patient with severe hypertension was found to have mildly impaired 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) activity on the basis of urinary steroid metabolite ratios, low plasma aldosterone, angiotensin II and renin levels and marginally low levels of plasma potassium.	Potassium	272-281	carbohydrate sulfotransferase 3	Homo sapiens	115-118
8645223-5	1996	(2) Kinetic analysis indicated that the inhibitory mode of KS-505a for the 61 kDa isoenzyme was competitive with respect to Ca2+/CaM; the K1 for KS-505a was 0.089 microM.	Potassium	59-61	calmodulin 1	Rattus norvegicus	129-132
8645223-9	1996	Taken together, these results suggest that KS-505a apparently bound to a site in the Ca2+/CaM-binding domain of the 61 kDa isoenzyme and selectively inhibited Ca2+/CaM-activated 61 kDa isoenzyme activity.	Potassium	43-45	calmodulin 1	Rattus norvegicus	90-93
8645223-9	1996	Taken together, these results suggest that KS-505a apparently bound to a site in the Ca2+/CaM-binding domain of the 61 kDa isoenzyme and selectively inhibited Ca2+/CaM-activated 61 kDa isoenzyme activity.	Potassium	43-45	calmodulin 1	Rattus norvegicus	164-167
8635257-7	1996	The Ile593Arg mutation may result in a change in potassium selectivity and permeability leading to a loss of HERG function, thereby resulting in LQT.	Potassium	49-58	potassium voltage-gated channel subfamily H member 2	Homo sapiens	109-113
8626822-0	1996	Body composition derived from whole body counting of potassium in growth hormone-deficient adults: a possible low intracellular potassium concentration.	Potassium	128-137	growth hormone 1	Homo sapiens	66-80
8813350-2	1996	The Kv1.1 channel was expressed in oocytes of Xenopus laevis and potassium currents were investigated in outside-out and inside-out membrane patches.	Potassium	65-74	potassium channel, voltage gated shaker related subfamily A, member 1 S homeolog	Xenopus laevis	4-9
8809443-3	1996	Body composition was measured by a four compartment method, which by combining determinations of total body water and total body potassium allows a distinction between the two variable components of fat free mass (FFM): BCM and extracellular water (ECW).	Potassium	129-138	TNF receptor superfamily member 17	Homo sapiens	220-223
8638845-8	1996	CONCLUSIONS: Although both ketamine and halothane inhibit potassium currents through the Kv2.1 channel, their mechanisms of action at this potential target may be different.	Potassium	58-67	potassium voltage-gated channel subfamily B member 1	Homo sapiens	89-94
8780004-1	1996	Membrane depolarization stimuli (high potassium concentration and veratridine) increased neuropeptide Y (NPY) mRNA abundance time-dependently, without a change in beta-actin mRNA level, in NG108-15 and PC12 cells.	Potassium	38-47	neuropeptide Y	Mus musculus	89-103
8780004-1	1996	Membrane depolarization stimuli (high potassium concentration and veratridine) increased neuropeptide Y (NPY) mRNA abundance time-dependently, without a change in beta-actin mRNA level, in NG108-15 and PC12 cells.	Potassium	38-47	neuropeptide Y	Mus musculus	105-108
8784785-16	1996	Stimulation by immunosuppressants of transmitter release in potassium depolarized synaptosomes may result from augmented phosphorylation of synapsin I, whose phosphorylation is known to facilitate transmitter release.	Potassium	60-69	synapsin I	Rattus norvegicus	140-150
8887965-5	1996	In all control groups, application of potassium ions (60 mM) evoked a significant release of acetylcholinesterase in the substantia nigra (p < 0.05) and this effect persisted in the surviving neurones following a partial lesion by neurotoxin pre-treatment.	Potassium	38-47	acetylcholinesterase	Cavia porcellus	93-113
9812742-5	1996	CONCLUSION: The mechanism of anti-arrhythmic action of EBP was to prolong the APD through inhibiting the delayed rectified potassium current.	Potassium	123-132	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Cavia porcellus	55-58
8621781-7	1996	Consequently, we studied the effect in rats of 11 days" potassium deprivation on urine production and AQP2 expression and distribution.	Potassium	56-65	aquaporin 2	Rattus norvegicus	102-106
8621781-11	1996	After return to a potassium-containing diet both urine output and AQP2 labels normalized within 7 d. Immunocytochemistry confirmed decreased AQP2 labeling in principal cells of both inner medullary and cortical collecting ducts.	Potassium	18-27	aquaporin 2	Rattus norvegicus	66-70
8621781-11	1996	After return to a potassium-containing diet both urine output and AQP2 labels normalized within 7 d. Immunocytochemistry confirmed decreased AQP2 labeling in principal cells of both inner medullary and cortical collecting ducts.	Potassium	18-27	aquaporin 2	Rattus norvegicus	141-145
8967334-1	1996	Chronic potassium restriction leads to active potassium reabsorption in the late distal nephron and collecting duct, segments known to express "gastric" H(+)-K(+)-adenosinetriphosphatase (H(+)-K(+)-ATPase) alpha-subunit mRNA.	Potassium	8-17	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	188-219
8818978-10	1996	The biochemical studies indicated that glucagon could be released from the retina in a calcium dependent manner by high potassium stimulation.	Potassium	120-129	glucagon	Homo sapiens	39-47
8728473-0	1996	Tetrahydroberberine suppresses dopamine-induced potassium current in acutely dissociated CA1 pyramidal neurons from rat hippocampus.	Potassium	48-57	carbonic anhydrase 1	Rattus norvegicus	89-92
8609894-2	1996	After transfection with IRK1 and m1 muscarinic receptor genes, tsA cells expressed a cesium-sensitive inwardly rectifying potassium conductance that was reduced on application of the muscarinic receptor agonist carbachol.	Potassium	122-131	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	24-28
12239394-0	1996	SOS1, a Genetic Locus Essential for Salt Tolerance and Potassium Acquisition.	Potassium	55-64	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	0-4
12239394-8	1996	Uptake experiments using 86Rb showed that sos1 mutants are defective in high-affinity potassium uptake.	Potassium	86-95	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	42-46
12239394-9	1996	sos1 plants became deficient in potassium when treated with NaCl.	Potassium	32-41	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	0-4
8607800-3	1996	Co-expression of rat Kir6.2 and sulfonylurea receptor in human embryonic kidney cells generated a potassium current with the properties of the beta-cell ATP-sensitive potassium channel.	Potassium	98-107	potassium inwardly-rectifying channel, subfamily J, member 11	Rattus norvegicus	21-27
8613967-1	1996	The mu-opioid receptor is an autoreceptor on hypothalamic beta-endorphin neurons that when activated inhibits cell firing via increasing an inwardly rectifying potassium conductance.	Potassium	160-169	mu-type opioid receptor	Cavia porcellus	4-22
8760461-1	1996	The properties of the inward-rectifying potassium current (IK1) were studied in the single myocytes isolated from adult mouse ventricles by the whole-cell patch-clamp technique for the first time.	Potassium	40-49	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	59-62
8609894-9	1996	As IRK1 is widely distributed throughout the central nervous system, it is possible that such an action on IRK1 underlies the inhibitory effects of muscarinic receptor stimulation on inwardly rectifying potassium conductances observed in the brain.	Potassium	203-212	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	3-7
8609894-9	1996	As IRK1 is widely distributed throughout the central nervous system, it is possible that such an action on IRK1 underlies the inhibitory effects of muscarinic receptor stimulation on inwardly rectifying potassium conductances observed in the brain.	Potassium	203-212	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	107-111
8868050-1	1996	We have studied potassium currents through a cloned Ca(2+)-dependent K+ channel (hslo) from human myometrium.	Potassium	16-25	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	81-85
8710161-1	1996	Whole-cell outward potassium currents (IK) were measured in interferon (IFN)-gamma-activated cultured murine microglial cells.	Potassium	19-28	interferon gamma	Mus musculus	60-82
8603696-0	1996	Streptozotocin, an inducer of NAD+ decrease, attenuates M-potassium current inhibition by ATP, bradykinin, angiotensin II, endothelin 1 and acetylcholine in NG108-15 cells.	Potassium	58-67	endothelin 1	Mus musculus	123-135
8804117-10	1996	Nerve terminals are highly concentrated in the superficial laminae of the dorsal horn, where NPFF-immunoreactivity can be released by, e.g., potassium and substance P.	Potassium	141-150	neuropeptide FF-amide peptide precursor	Homo sapiens	93-97
8852815-8	1996	A concentration-dependent in vitro release of potassium from tissues of parotid and submandibular glands in response to NPY occurred and here, submandibular gland tissue was the most sensitive.	Potassium	46-55	neuropeptide Y	Rattus norvegicus	120-123
8815525-5	1996	Insulin therapy is associated with precocious sodium and potassium replacement, and with gradual rehydration coupled to intensive monitoring.	Potassium	57-66	insulin	Homo sapiens	0-7
8621734-0	1996	Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approximately 80-kDa mdr1a gene product.	Potassium	13-22	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	Mus musculus	123-128
8603696-1	1996	The M-potassium current was inhibited by bath application of 100 micron ATP, 10 nM bradykinin, 100 nM angiotensin II and 100 nM endothelin 1 as well as by 10 micron acetylcholine in an m1-muscarinic acetylcholine receptor-transformed NG108-15 cell line.	Potassium	6-15	endothelin 1	Mus musculus	128-140
8789096-1	1996	Extracellular potassium modulates recovery from C-type inactivation of Kv1.3 in human T lymphocytes.	Potassium	14-23	potassium voltage-gated channel subfamily A member 3	Homo sapiens	71-76
8635540-7	1996	Elevated potassium concentration 24.2 mM) in the culture medium during development significantly increased neuronal vulnerability to Glu treatment, indicated by a higher increase of NSE content in the medium and by a more pronounced Glu-induced decrease of the number of TH-IR cells.	Potassium	9-18	enolase 2	Rattus norvegicus	182-185
8800898-5	1996	The amount of VIP released in vitro by high potassium concentration or veratridine was similar for penile tissue slices of normal and diabetic rats.	Potassium	44-53	vasoactive intestinal peptide	Rattus norvegicus	14-17
8602670-10	1996	There was a significant positive correlation between maximal change in blood potassium concentration and the respective AChR concentration in the gastrocnemius of the same animal (r = 0.81, P<0.01).	Potassium	77-86	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	120-124
8602670-13	1996	The magnitude of the increase in blood potassium to SCh was directly dependent on AChR number.	Potassium	39-48	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	82-86
8785398-8	1996	In water-deprived, sodium-loaded, and potassium-loaded rats, the inner medullary sorbitol content increased significantly in accordance with the rise in the enzymatic activity and the level of aldose reductase mRNA.	Potassium	38-47	aldo-keto reductase family 1 member B1	Rattus norvegicus	193-209
8777958-8	1996	Serum potassium was significantly lower both before (4.0 +/- 0.2 mmol.L-1) and after (3.9 +/- 0.2 mmol.L-1) the withdrawal of oral beta 2-agonists compared with the control group (4.2 +/- 0.2 mmol.L-1).	Potassium	6-15	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	131-137
8820606-1	1996	AKT1, a putative inwardly directed K+ channel of Arabidopsis, restores long-term potassium uptake in a yeast mutant defective in K+ absorption.	Potassium	81-90	K+ transporter 1	Arabidopsis thaliana	0-4
8820905-0	1996	A cyclic AMP analog and high potassium prevent the death of cultured septal cholinergic neurons after nerve growth factor withdrawal.	Potassium	29-38	nerve growth factor	Homo sapiens	102-121
9053775-9	1996	Potassium challenge (56 mM KCl) significantly stimulated LHRH release from the ME of both intact and castrate male rats suggesting that all tissues were able to respond to a stimulus, and that castration did not alter the responsiveness of the LHRH neuron to a nonspecific secretagogue.	Potassium	0-9	gonadotropin releasing hormone 1	Rattus norvegicus	57-61
8551342-0	1996	A slowly inactivating potassium current in CA3 pyramidal cells of rat hippocampus in vitro.	Potassium	22-31	carbonic anhydrase 3	Rattus norvegicus	43-46
8549659-9	1996	However, in cells treated with the potassium ionophore nonactin, which blocks mitochondrial import, only the precursor form of Hsp60 accumulates, providing evidence that at least partial mitochondrial import of Hsp60 is necessary for its maturation.	Potassium	35-44	heat shock protein family D (Hsp60) member 1	Homo sapiens	127-132
8549659-9	1996	However, in cells treated with the potassium ionophore nonactin, which blocks mitochondrial import, only the precursor form of Hsp60 accumulates, providing evidence that at least partial mitochondrial import of Hsp60 is necessary for its maturation.	Potassium	35-44	heat shock protein family D (Hsp60) member 1	Homo sapiens	211-216
8787195-1	1996	Incubation of hypothalamo-neurohypophysial explants in Locke"s solution containing 28 nM/L thyrotropin-releasing hormone (TRH) resulted in an inhibition of vasopressin and oxytocin secretion during depolarization due to excess potassium.	Potassium	227-236	thyrotropin releasing hormone	Rattus norvegicus	91-120
8787195-1	1996	Incubation of hypothalamo-neurohypophysial explants in Locke"s solution containing 28 nM/L thyrotropin-releasing hormone (TRH) resulted in an inhibition of vasopressin and oxytocin secretion during depolarization due to excess potassium.	Potassium	227-236	thyrotropin releasing hormone	Rattus norvegicus	122-125
8596709-4	1996	Kir activity increased with elevation of extracellular potassium and was blocked by extracellular Cs+ or Ba2+ Antisense oligodeoxynucleotides directed against Kir blocked both mRNA and functional expression of Kir channels.	Potassium	55-64	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	0-3
8596709-4	1996	Kir activity increased with elevation of extracellular potassium and was blocked by extracellular Cs+ or Ba2+ Antisense oligodeoxynucleotides directed against Kir blocked both mRNA and functional expression of Kir channels.	Potassium	55-64	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	159-162
8596709-4	1996	Kir activity increased with elevation of extracellular potassium and was blocked by extracellular Cs+ or Ba2+ Antisense oligodeoxynucleotides directed against Kir blocked both mRNA and functional expression of Kir channels.	Potassium	55-64	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	159-162
8825352-23	1996	By use of conventional whole cell recording methods and conditions that suppressed BKCa openings, outward potassium currents were activated by depolarizing potentials positive to -35 mV from a holding potential of -65 mV.	Potassium	106-115	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	83-87
8569718-8	1996	Ang II-induced G alpha q/G alpha 11 down-regulation was reversed by prevention of cellular receptor processing with phenylarsine oxide or chronic potassium depletion.	Potassium	146-155	angiotensinogen	Rattus norvegicus	0-6
8536617-2	1996	High potassium-induced membrane depolarization and calcium influx have previously been shown to activate kinases that phosphorylate and thereby activate the transcription factor cAMP response element (CRE-binding protein (CREB) binding to CREs.	Potassium	5-14	cAMP responsive element binding protein 1	Homo sapiens	201-220
8536617-2	1996	High potassium-induced membrane depolarization and calcium influx have previously been shown to activate kinases that phosphorylate and thereby activate the transcription factor cAMP response element (CRE-binding protein (CREB) binding to CREs.	Potassium	5-14	cAMP responsive element binding protein 1	Homo sapiens	222-226
8536617-2	1996	High potassium-induced membrane depolarization and calcium influx have previously been shown to activate kinases that phosphorylate and thereby activate the transcription factor cAMP response element (CRE-binding protein (CREB) binding to CREs.	Potassium	5-14	cystatin 8	Homo sapiens	239-243
8866625-0	1996	Effect of beta 2-adrenoceptor agonists on plasma potassium and cardiopulmonary responses on exercise in patients with chronic obstructive pulmonary disease.	Potassium	49-58	adrenoceptor beta 2	Homo sapiens	10-29
8929628-7	1996	Patients with oxytocin resistant labour had lower intracellular potassium (p < .0006) and phosphorus (p < .02), and higher chloride (p < .05) and sodium (p < .03) compared to levels found in patients who responded to oxytocin treatment.	Potassium	64-73	oxytocin/neurophysin I prepropeptide	Homo sapiens	14-22
8929628-9	1996	The reduced level of potassium and phosphorus together with the high sodium and chloride levels found in patients with oxytocin resistant labour may be connected to an impairment in sodium-potassium pump and muscle dysfunction, clinically diagnosed as dystocia.	Potassium	21-30	oxytocin/neurophysin I prepropeptide	Homo sapiens	119-127
8719027-1	1996	The 5-hydroxytryptamine1A (5-HT1A) receptor in the CA1 region of the hippocampus is linked through a G protein to an inwardly rectifying potassium conductance.	Potassium	137-146	5-hydroxytryptamine receptor 1A	Rattus norvegicus	4-25
8719027-1	1996	The 5-hydroxytryptamine1A (5-HT1A) receptor in the CA1 region of the hippocampus is linked through a G protein to an inwardly rectifying potassium conductance.	Potassium	137-146	5-hydroxytryptamine receptor 1A	Rattus norvegicus	27-33
8719027-1	1996	The 5-hydroxytryptamine1A (5-HT1A) receptor in the CA1 region of the hippocampus is linked through a G protein to an inwardly rectifying potassium conductance.	Potassium	137-146	carbonic anhydrase 1	Rattus norvegicus	51-54
8592732-3	1996	Potassium currents in the myocardium can be classified into one of two general categories: 1) inward rectifying currents such as IK1, IKACh, and IKATP; and 2) primarily voltage-gated currents such as IKs, IKr, IKp, IKur, and Ito.	Potassium	0-9	potassium calcium-activated channel subfamily N member 4	Homo sapiens	129-132
8592732-3	1996	Potassium currents in the myocardium can be classified into one of two general categories: 1) inward rectifying currents such as IK1, IKACh, and IKATP; and 2) primarily voltage-gated currents such as IKs, IKr, IKp, IKur, and Ito.	Potassium	0-9	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	145-157
8911881-10	1996	Based on simulation, our model predicted that a continuous infusion of 2.0 micrograms.min-1 (highest rate examined) would increase heart rate to 113 beats.min-1 at steady state and lower the plasma potassium concentration to 2.77 mmol.1(-1) 1.5 h after beginning the infusion.	Potassium	198-207	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
8911881-10	1996	Based on simulation, our model predicted that a continuous infusion of 2.0 micrograms.min-1 (highest rate examined) would increase heart rate to 113 beats.min-1 at steady state and lower the plasma potassium concentration to 2.77 mmol.1(-1) 1.5 h after beginning the infusion.	Potassium	198-207	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8852501-5	1996	Intravenous infusion of insulin and glucose (5 mU/kg/min for 60 min) significantly lowered plasma potassium from 6.3 +/- 0.1 to 5.7 +/- 0.1 mEq/l (p < 0.01).	Potassium	98-107	insulin	Homo sapiens	24-31
8852501-6	1996	The combined infusion of bicarbonate and insulin with glucose showed the greatest decline in plasma potassium, from 6.2 +/- 0.2 to 5.2 +/- 0.1 mEq/l (p < 0.01).	Potassium	100-109	insulin	Homo sapiens	41-48
8938715-0	1996	Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes.	Potassium	0-9	ether a go-go	Drosophila melanogaster	55-58
8848143-0	1996	Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: protection by cyclic AMP analogue and high potassium.	Potassium	153-162	nerve growth factor	Homo sapiens	0-19
8821750-12	1995	Angiotensin II attenuated both the peak and the steady-state potassium currents, suggesting that angiotensin II may modulate area postrema activity by inhibiting voltage-gated potassium channels.	Potassium	61-70	angiotensinogen	Rattus norvegicus	0-14
8821750-12	1995	Angiotensin II attenuated both the peak and the steady-state potassium currents, suggesting that angiotensin II may modulate area postrema activity by inhibiting voltage-gated potassium channels.	Potassium	61-70	angiotensinogen	Rattus norvegicus	97-111
8569718-8	1996	Ang II-induced G alpha q/G alpha 11 down-regulation was reversed by prevention of cellular receptor processing with phenylarsine oxide or chronic potassium depletion.	Potassium	146-155	G protein subunit alpha q	Rattus norvegicus	15-24
8569718-8	1996	Ang II-induced G alpha q/G alpha 11 down-regulation was reversed by prevention of cellular receptor processing with phenylarsine oxide or chronic potassium depletion.	Potassium	146-155	G protein subunit alpha 11	Rattus norvegicus	25-35
8878363-3	1996	The chemical analysis of fog during 32 episodes of local fog (pH, chloride, nitrate, sulphate, sodium, ammonia, potassium, magnesium, calcium) has shown a greater concentration of pollutants and greater acidity in the smaller particles (2-6 microns) which are able to penetrate the bronchial tree.	Potassium	112-121	zinc finger protein, FOG family member 1	Homo sapiens	25-28
8530381-5	1995	Here we demonstrate that the mt-Hsp70.Mim44 complex contains ADP and that a nonhydrolyzable analog of ATP dissociates the mt-Hsp70.Mim44 complex in the presence of potassium ions.	Potassium	164-173	heat shock protein family A (Hsp70) member 4	Homo sapiens	32-37
8847404-5	1995	In vivo electrochemical recordings in the ipsilateral caudate and putamen 3 weeks after GDNF administration revealed increased potassium-evoked release of dopamine in trophic factor recipients.	Potassium	127-136	glial cell derived neurotrophic factor	Macaca mulatta	88-92
8530381-5	1995	Here we demonstrate that the mt-Hsp70.Mim44 complex contains ADP and that a nonhydrolyzable analog of ATP dissociates the mt-Hsp70.Mim44 complex in the presence of potassium ions.	Potassium	164-173	heat shock protein family A (Hsp70) member 4	Homo sapiens	125-130
8530381-7	1995	In the presence of potassium ions, mt-Hsp70 undergoes a conformational change that is not observed with a mutant Hsp70 defective in binding to Mim44.	Potassium	19-28	heat shock protein family A (Hsp70) member 9	Homo sapiens	35-43
8530381-7	1995	In the presence of potassium ions, mt-Hsp70 undergoes a conformational change that is not observed with a mutant Hsp70 defective in binding to Mim44.	Potassium	19-28	heat shock protein family A (Hsp70) member 4	Homo sapiens	38-43
8574549-3	1995	Chlortoluron produced a type I binding spectrum with cytochrome P450 3A4 with a Ks value of 200 microM.	Potassium	80-82	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	53-72
7588295-6	1995	Furthermore, depolarizing concentrations of potassium (56 mM) increased by 3-fold the release of immunoreactive PRL by incubated hypothalamo-neurohypophyseal explants.	Potassium	44-53	prolactin	Rattus norvegicus	112-115
7502075-0	1995	Sodium-driven potassium uptake by the plant potassium transporter HKT1 and mutations conferring salt tolerance.	Potassium	14-23	cation transporter HKT1	Triticum aestivum	66-70
7490138-8	1995	After ANP gene delivery, there were significant increases in urinary volume and urinary potassium output (n = 6, P < .05) but not in body weight, heart rate, water intake, urinary sodium output, urinary creatine, and urinary protein.	Potassium	88-97	natriuretic peptide A	Homo sapiens	6-9
8566020-4	1995	The KS cells after MLR were predominantly CD3+, CD25+, HLA-DR+, Ki67+ and CD45RO+ T cells, and the CD4/CD8 ratio was heterogeneous (from 0.8 to 2.7).	Potassium	4-6	interleukin 2 receptor subunit alpha	Homo sapiens	48-52
8566020-4	1995	The KS cells after MLR were predominantly CD3+, CD25+, HLA-DR+, Ki67+ and CD45RO+ T cells, and the CD4/CD8 ratio was heterogeneous (from 0.8 to 2.7).	Potassium	4-6	CD4 molecule	Homo sapiens	74-77
8555458-0	1995	Organization and expression of the gene coding for the potassium transport system AKT1 of Arabidopsis thaliana.	Potassium	55-64	K+ transporter 1	Arabidopsis thaliana	82-86
8720036-4	1995	(2) ANP infusion significantly increased urine flow rate (UFR), creatinine clearance (CCr), fractional excretion rates of sodium (FENa) and chloride (FECl), and urinary phosphorus and magnesium (Mg) excretions in a dose-dependent manner without affecting renal plasma flow and fractional excretion rates of potassium and urea in cisplatin-treated rats.	Potassium	307-316	natriuretic peptide A	Rattus norvegicus	4-7
7490619-11	1995	Thrombin-induced brain edema was accompanied by increases in brain sodium and chloride contents and a decrease in brain potassium content.	Potassium	120-129	coagulation factor II	Rattus norvegicus	0-8
8555458-1	1995	We have isolated and sequenced the genomic clone coding for the potassium transport system AKT1 of Arabidopsis thaliana.	Potassium	64-73	K+ transporter 1	Arabidopsis thaliana	91-95
7502040-3	1995	Coexpression with the sulfonylurea receptor SUR reconstituted an inwardly rectifying potassium conductance of 76 picosiemens that was sensitive to adenosine triphosphate (ATP) (IKATP) and was inhibited by sulfonylureas and activated by diazoxide.	Potassium	85-94	ATP binding cassette subfamily C member 8	Homo sapiens	44-47
8581477-5	1995	Application of mGluR agonist t-ACPD inhibited both the peak and the steady state voltage-gated potassium current in 39 out of 56 visceral afferent neurons tested (70%) by 22.0 +/- 3 and 22.8 +/- 2%, respectively.	Potassium	95-104	homer scaffold protein 2	Homo sapiens	31-35
8581477-7	1995	Increasing the holding potential from -100 mV to -30 mV only partially attenuated the inhibitory effects of t-ACPD (decreased effect by 11%), suggesting that t-ACPD modulates both a voltage insensitive and a voltage-sensitive potassium current.	Potassium	226-235	homer scaffold protein 2	Homo sapiens	160-164
7593351-3	1995	Nitric oxide synthase (NOS) inhibition by brain topical superfusion with N omega-nitro-L-arginine (L-NA) revealed (a) Addition of L-NA to high-potassium ACSF reduced the rCBF increase from +94 +/- 36% to +21 +/- 18% (p < or = 0.01, n = 7).	Potassium	143-152	nitric oxide synthase 2	Homo sapiens	0-21
7490555-0	1995	Growth hormone (GH) receptor and GH-binding protein deficiency in the growth failure of potassium-depleted rats.	Potassium	88-97	growth hormone receptor	Rattus norvegicus	0-28
7473173-10	1995	In conclusion, the present results showed that long-term angiotensin-converting enzyme inhibition in parallel reduced plasma digoxin-like factor, enhanced arterial potassium relaxation (probably reflecting enhanced function of Na+,K(+)-ATPase) and normalized plasma Na+:K+ ratio in this type of genetic hypertension.	Potassium	164-173	angiotensin I converting enzyme	Rattus norvegicus	57-86
8576855-0	1995	Voltage-gated potassium currents in stratum oriens-alveus inhibitory neurones of the rat CA1 hippocampus.	Potassium	14-23	carbonic anhydrase 1	Rattus norvegicus	89-92
8576856-0	1995	Potassium conductances underlying repolarization and after-hyperpolarization in rat CA1 hippocampal interneurones.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	84-87
7570021-3	1995	Ryanodine and thapsigargin inhibited Ca2+ sparks and Ca(2+)-dependent potassium (KCa) currents, suggesting that Ca2+ sparks activate KCa channels.	Potassium	70-79	casein kappa	Homo sapiens	81-84
7592636-4	1995	Six of these mutated KAT1 cDNAs complemented a K+ uptake-deficient yeast strain at low concentrations of potassium.	Potassium	105-114	histone acetyltransferase catalytic subunit HAT1	Saccharomyces cerevisiae S288C	21-25
8592191-2	1995	The properties of voltage-gated potassium currents were studied in acutely isolated rat hippocampal pyramidal cells from area CA1 and CA3 at postnatal ages of day 6-8, 9-14, and 26-29 (P6-8, P9-14, and P26-29) with the use of the whole cell version of the patch-clamp technique.	Potassium	32-41	carbonic anhydrase 1	Rattus norvegicus	126-129
8592191-2	1995	The properties of voltage-gated potassium currents were studied in acutely isolated rat hippocampal pyramidal cells from area CA1 and CA3 at postnatal ages of day 6-8, 9-14, and 26-29 (P6-8, P9-14, and P26-29) with the use of the whole cell version of the patch-clamp technique.	Potassium	32-41	KH RNA binding domain containing, signal transduction associated 1	Rattus norvegicus	185-189
8592208-0	1995	G alpha o1 decapeptide modulates the hippocampal 5-HT1A potassium current.	Potassium	56-65	5-hydroxytryptamine receptor 1A	Homo sapiens	49-55
8592208-2	1995	The serotonin1A (5-HT1A) receptor is coupled to an inwardly rectifying potassium current (IKir) via a G protein.	Potassium	71-80	5-hydroxytryptamine receptor 1A	Homo sapiens	4-33
7577962-0	1995	Aggregation of acidic lipid vesicles by myelin basic protein: dependence on potassium concentration.	Potassium	76-85	myelin basic protein	Homo sapiens	40-60
7570021-3	1995	Ryanodine and thapsigargin inhibited Ca2+ sparks and Ca(2+)-dependent potassium (KCa) currents, suggesting that Ca2+ sparks activate KCa channels.	Potassium	70-79	casein kappa	Homo sapiens	133-136
8777900-0	1995	Evidence for decreased calcium dependent potassium conductance in hippocampal CA3 neurons of genetically epilepsy-prone rats.	Potassium	41-50	carbonic anhydrase 3	Rattus norvegicus	78-81
8640353-2	1995	We have studied three hypoxia-induced phenomena in the CA1 stratum pyramidale of the rat hippocampal slice: (a) the increase in extracellular potassium ion concentration ([K+]e) measured with ion-sensitive microelectrodes, (b) the intracellularly-recorded pyramidal cell hyperpolarization and (c) the extracellularly-recorded depression of the synaptically-evoked field potential recorded in stratum pyramidale.	Potassium	142-151	carbonic anhydrase 1	Rattus norvegicus	55-58
8575169-6	1995	Potassium-induced depolarization around the probe tip located in the preoptic area and in the hypothalamus induced an increase in SS concentrations in dialysate at each location.	Potassium	0-9	somatostatin	Capra hircus	130-132
7485470-9	1995	These data argue that ATP1AL1 is the catalytic alpha-subunit of a human nongastric P-type ATPase capable of exchanging extracellular potassium for intracellular protons.	Potassium	133-142	ATPase H+/K+ transporting non-gastric alpha2 subunit	Homo sapiens	22-29
8777900-7	1995	Since calcium dependent potassium conductance produces both spike frequency adaptation and AHP, our results suggest that this conductance is reduced in the GEPR CA3 neurons.	Potassium	24-33	carbonic anhydrase 3	Rattus norvegicus	161-164
8547550-11	1995	Venous ET-1 levels were significantly correlated with venous oxygen content, pH, PO2, oxygen saturation, base excess, blood sodium concentration, and potassium concentration.	Potassium	150-159	endothelin 1	Homo sapiens	7-11
8589279-4	1995	Moreover, the beta-adrenergic agonist albuterol has been shown to be a useful adjunct to insulin for acutely lowering plasma potassium.	Potassium	125-134	insulin	Homo sapiens	89-96
7472417-1	1995	Rat brain cannabinoid receptor (CB-1) was stably transfected into the murine tumor line AtT-20 to study its coupling to inwardly rectifying potassium currents (Kir) and high voltage-activated calcium currents (ICa).	Potassium	140-149	cannabinoid receptor 1 (brain)	Mus musculus	32-36
8593294-11	1995	Our findings indicate that VIP stimulates the jejunal secretion of water, sodium, potassium and bicarbonate and that VIP does not inhibit glucose absorption when the secretion of luminal fluid is accelerated by VIP in the jejunal loop of sheep.	Potassium	82-91	vasoactive intestinal peptide	Ovis aries	27-30
7554128-8	1995	The rat Cx40 channel had a maximum conductance of 180 +/- 18 pS (n = 3) in 120 mmol/L KCl and a detectable chloride permeability of 0.29 relative to potassium, indicating some selectivity for cations over anions.	Potassium	149-158	gap junction protein, alpha 5	Rattus norvegicus	8-12
7501604-10	1995	When the potassium level is < or = 3.9 mmol/l the aldosterone/renin ratio should be measured in supine position since it evaluates the dissociation between renin and aldosterone seen in primary hyperaldosteronism.	Potassium	9-18	renin	Homo sapiens	159-164
8519990-4	1995	Recent data show that injections of high concentrations of min K mRNA also induce a chloride current with very different biophysical, pharmacological, and regulatory properties from the min K potassium current.	Potassium	192-201	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	59-64
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	22-24	tumor associated calcium signal transducer 2	Homo sapiens	40-47
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	22-24	tumor associated calcium signal transducer 2	Homo sapiens	89-96
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	22-24	tumor associated calcium signal transducer 2	Homo sapiens	89-96
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	71-73	tumor associated calcium signal transducer 2	Homo sapiens	40-47
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	71-73	tumor associated calcium signal transducer 2	Homo sapiens	89-96
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	71-73	tumor associated calcium signal transducer 2	Homo sapiens	89-96
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	71-73	tumor associated calcium signal transducer 2	Homo sapiens	40-47
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	71-73	tumor associated calcium signal transducer 2	Homo sapiens	89-96
8549644-4	1995	Their rate constants (ks = 1.1 x 10(12) M-1 s-1 for oxymethazoline and ks = 4.7 x 10(10) M-1 s-1 for xylomethazoline) exceeded the rate constant of a known powerful scavenger cimetidine (ks = 1.8 x 10(10) M-1 s-1).	Potassium	71-73	tumor associated calcium signal transducer 2	Homo sapiens	89-96
8519990-4	1995	Recent data show that injections of high concentrations of min K mRNA also induce a chloride current with very different biophysical, pharmacological, and regulatory properties from the min K potassium current.	Potassium	192-201	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	186-191
9384677-6	1995	Likewise, TNF-alpha and/or INF-gamma augmented T cell proliferation induced by CD80-transfected KS cells.	Potassium	96-98	tumor necrosis factor	Homo sapiens	10-19
7568043-0	1995	Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.	Potassium	44-53	fructose-bisphosphatase 1	Sus scrofa	85-112
9384677-6	1995	Likewise, TNF-alpha and/or INF-gamma augmented T cell proliferation induced by CD80-transfected KS cells.	Potassium	96-98	CD80 molecule	Homo sapiens	79-83
9384677-3	1995	In order to reconstitute the potential to induce primary T cell activation, we transfected CD80 into a breast (KS) and an ovarian carcinoma (GG) cell line.	Potassium	111-113	CD80 molecule	Homo sapiens	91-95
9384677-7	1995	Furthermore, T lymphocytes stimulated with cytokine-treated CD80+ KS cells gave rise to a long term proliferating CD8+ CTL line with class I MHC restricted cytolytic antitumor activity.	Potassium	66-68	CD80 molecule	Homo sapiens	60-64
9384677-4	1995	CD80 expression in KS cells resulted in improved primary T cell activation, whereas it was ineffective in the case of GG cells.	Potassium	19-21	CD80 molecule	Homo sapiens	0-4
9384677-7	1995	Furthermore, T lymphocytes stimulated with cytokine-treated CD80+ KS cells gave rise to a long term proliferating CD8+ CTL line with class I MHC restricted cytolytic antitumor activity.	Potassium	66-68	CD8a molecule	Homo sapiens	60-63
8534918-7	1995	gpIRK1 complements a trk1 delta trk2 delta strain, which is defective in potassium uptake.	Potassium	73-82	Trk1p	Saccharomyces cerevisiae S288C	21-25
8534918-7	1995	gpIRK1 complements a trk1 delta trk2 delta strain, which is defective in potassium uptake.	Potassium	73-82	Trk2p	Saccharomyces cerevisiae S288C	32-36
7501705-3	1995	Alteration of the concentration of Mg2+ may cause neuromuscular hyperactivity, psychiatric disturbances, calcium/potassium abnormalities, and overactivity of cardiac muscle.	Potassium	113-122	mucin 7, secreted	Homo sapiens	35-38
7473243-16	1995	Raising the external potassium concentration from 3.5 to 8.5 mM, which elicited burst firing in CA3 pyramidal cells, resulted in a barrage of EPSCs and action potentials in basket cells.	Potassium	21-30	carbonic anhydrase 3	Rattus norvegicus	96-99
7642616-4	1995	In contrast, aptamers selected against R70E thrombin were able to bind and inhibit both wild-type and R70E thrombins, and displayed potassium-independent inhibition.	Potassium	132-141	coagulation factor II, thrombin	Homo sapiens	44-52
8527655-7	1995	The concentration dependence of hKv1.5 inhibition revealed apparent KD values of 27.3 +/- 2.8 and 4.1 +/- 0.7 microM for S(-)-bupivacaine and R(+)-bupivacaine, respectively, with Hill coefficients close to unity, suggesting that binding of one enantiomer molecule per channel was sufficient to block potassium permeation.	Potassium	300-309	potassium voltage-gated channel subfamily A member 5	Homo sapiens	32-38
7629980-0	1995	Diet and serum potassium in patients on ACE inhibitors.	Potassium	15-24	angiotensin I converting enzyme	Homo sapiens	40-43
7589016-2	1995	However, there was a significant increase in body weight with beta-blockers and changes in the body potassium homeostasis with ACE inhibitors.	Potassium	100-109	angiotensin I converting enzyme	Homo sapiens	127-130
7473194-2	1995	Block by external tetraethylammonium (TEA) was examined on currents carried by potassium (K+) and sodium (Na+) through the cloned delayed rectifier K+ channel Kv2.1.	Potassium	79-88	potassium voltage-gated channel subfamily B member 1	Homo sapiens	159-164
7472364-2	1995	An in vitro slice model of ischemia was used to study changes in extracellular potassium concentration and diffusion properties in the stratum pyramidale of CA1 and CA3 regions of the hippocampus and in the cortex of the rat.	Potassium	79-88	carbonic anhydrase 1	Rattus norvegicus	157-160
7472364-2	1995	An in vitro slice model of ischemia was used to study changes in extracellular potassium concentration and diffusion properties in the stratum pyramidale of CA1 and CA3 regions of the hippocampus and in the cortex of the rat.	Potassium	79-88	carbonic anhydrase 3	Rattus norvegicus	165-168
7472364-6	1995	The bathing medium contained 5 mM potassium, and in vitro ischemia caused the potassium concentration to rise to 45 mM in CA1, 12 mM in CA3, and 32 mM in cortex.	Potassium	78-87	carbonic anhydrase 1	Rattus norvegicus	122-125
7472364-6	1995	The bathing medium contained 5 mM potassium, and in vitro ischemia caused the potassium concentration to rise to 45 mM in CA1, 12 mM in CA3, and 32 mM in cortex.	Potassium	78-87	carbonic anhydrase 3	Rattus norvegicus	136-139
7478230-2	1995	The injection of ANGII into LV in rats with volume expansion reduced the sodium, potassium and urine excretion in comparison to the control injections of isotonic saline, whereas prazosin (alpha 1 antagonist) potentiated these effects.	Potassium	81-90	angiotensinogen	Rattus norvegicus	17-22
7618108-3	1995	On removal of potassium, Kv2.1 displayed a large sodium conductance that was inhibited by low concentrations of potassium.	Potassium	14-23	potassium voltage-gated channel subfamily B member 1	Homo sapiens	25-30
7618108-3	1995	On removal of potassium, Kv2.1 displayed a large sodium conductance that was inhibited by low concentrations of potassium.	Potassium	112-121	potassium voltage-gated channel subfamily B member 1	Homo sapiens	25-30
7618108-5	1995	In contrast, Kv1.5 displayed a negligible sodium conductance on removal of potassium.	Potassium	75-84	potassium voltage-gated channel subfamily A member 5	Homo sapiens	13-18
7581380-3	1995	In contrast, dominant myotonias sensitive to potassium are caused by point mutations in SCN4A on chromosome 17q, the gene for the alpha subunit of the adult skeletal muscle sodium channel.	Potassium	45-54	sodium voltage-gated channel alpha subunit 4	Homo sapiens	88-93
7628475-6	1995	In contrast, the Km values were increased, as was the Ks value for binding of CYP11A1 to the [H56T]adrenodoxin.	Potassium	54-56	cholesterol side-chain cleavage enzyme, mitochondrial	Bos taurus	78-85
7612008-1	1995	Secretin is a gastrointestinal hormone responsible for the regulation of bicarbonate, potassium ion and enzyme secretion from the pancreas.	Potassium	86-95	secretin	Homo sapiens	0-8
7604285-2	1995	The properties of HERG channels are consistent with the gating properties of Eag-related and other outwardly rectifying, S4-containing potassium channels, but with the addition of an inactivation mechanism that attenuates potassium efflux during depolarization.	Potassium	135-144	potassium voltage-gated channel subfamily H member 2	Homo sapiens	18-22
7604285-2	1995	The properties of HERG channels are consistent with the gating properties of Eag-related and other outwardly rectifying, S4-containing potassium channels, but with the addition of an inactivation mechanism that attenuates potassium efflux during depolarization.	Potassium	135-144	potassium voltage-gated channel subfamily H member 1	Homo sapiens	77-80
7582505-0	1995	The effect of neuropeptide Y on sodium, chloride and potassium transport across the rat distal colon.	Potassium	53-62	neuropeptide Y	Rattus norvegicus	14-28
8567442-0	1995	Evidence that glutathione is the unidentified amine (Unk 2.5) released by high potassium into cochlear fluids.	Potassium	79-88	unk zinc finger	Homo sapiens	53-56
7562882-7	1995	After ACE inhibition, fasting plasma potassium levels correlated with the decline in mean arterial BP (r = -0.71; P < 0.006).	Potassium	37-46	angiotensin I converting enzyme	Homo sapiens	6-9
7576598-0	1995	The secretion of parathyroid hormone-related protein in the saliva of sheep and its effects on the salivary clearance of phosphate, calcium, magnesium, potassium and sodium ions.	Potassium	152-161	parathyroid hormone-related protein	Ovis aries	17-52
7552360-5	1995	With potassium-free recording solutions, neurotensin evoked voltage-insensitive cationic currents.	Potassium	5-14	neurotensin	Rattus norvegicus	41-52
7598716-4	1995	Depolarization by potassium also resulted in DBH reduction which was reversed by the voltage dependent Ca++ channel blockers nifedipine and verapamil.	Potassium	18-27	dopamine beta-hydroxylase	Bos taurus	45-48
7672036-8	1995	Potassium-evoked dopamine release, measured using in vivo chronoamperometry, revealed significantly increased extracellular overflow in transplants treated with GDNF during development.	Potassium	0-9	glial cell derived neurotrophic factor	Homo sapiens	161-165
7552366-0	1995	Hydrogen peroxide hyperpolarizes rat CA1 pyramidal neurons by inducing an increase in potassium conductance.	Potassium	86-95	carbonic anhydrase 1	Rattus norvegicus	37-40
7552366-10	1995	We suggest that hydrogen peroxide is able to induce an increase in potassium conductance in rat CA1 pyramidal neurons.	Potassium	67-76	carbonic anhydrase 1	Rattus norvegicus	96-99
7666362-0	1995	Thrombin-induced inhibition of potassium currents in human retinal glial (Muller) cells.	Potassium	31-40	coagulation factor II, thrombin	Homo sapiens	0-8
7665693-8	1995	CONCLUSIONS: The high androgen levels in KS+ patients, particularly in the early stages of the disease (> 500 CD4 cells/mm3), may affect the immune system by inducing an abnormal cytokine profile, or by increasing T8 proliferation and activation, or both.	Potassium	41-44	CD4 molecule	Homo sapiens	113-116
7790911-0	1995	Effects of estradiol and progesterone on voltage-gated calcium and potassium conductances in rat CA1 hippocampal neurons.	Potassium	67-76	carbonic anhydrase 1	Rattus norvegicus	97-100
7761447-5	1995	Cyclic AMP-, protein kinase C-, and calmodulin-dependent second messenger pathways all modulated norepinephrine secretion caused by acetylcholine and high potassium and showed a distinct hierarchy in their effectiveness.	Potassium	155-164	calmodulin 1	Rattus norvegicus	36-46
7797497-0	1995	Inhibition of low threshold calcium channels by angiotensin II in adrenal glomerulosa cells through activation of protein kinase C. In adrenal glomerulosa cells, low threshold voltage-activated (T-type) calcium channels play a crucial role in coupling physiological variations of extracellular potassium to aldosterone biosynthesis.	Potassium	294-303	angiotensinogen	Homo sapiens	48-62
7768552-0	1995	Potassium negatively regulates angiotensin II type 1 receptor expression in human adrenocortical H295R cells.	Potassium	0-9	angiotensin II receptor type 1	Homo sapiens	31-61
7665693-5	1995	The KS+ patients with more than 500 CD4 lymphocytes per mm3 had significantly higher serum DHEA, DHEA sulphate, and testosterone than the KS- patients with the same CD4 counts; those with 500-200 CD4 cells/mm3 had higher serum DHEA and testosterone than the equivalent KS- men; and those with < 200 CD4 cells/mm3 had raised DHEA only compared with KS- men.	Potassium	4-6	CD4 molecule	Homo sapiens	36-39
7665693-5	1995	The KS+ patients with more than 500 CD4 lymphocytes per mm3 had significantly higher serum DHEA, DHEA sulphate, and testosterone than the KS- patients with the same CD4 counts; those with 500-200 CD4 cells/mm3 had higher serum DHEA and testosterone than the equivalent KS- men; and those with < 200 CD4 cells/mm3 had raised DHEA only compared with KS- men.	Potassium	4-6	CD4 molecule	Homo sapiens	165-168
7665693-5	1995	The KS+ patients with more than 500 CD4 lymphocytes per mm3 had significantly higher serum DHEA, DHEA sulphate, and testosterone than the KS- patients with the same CD4 counts; those with 500-200 CD4 cells/mm3 had higher serum DHEA and testosterone than the equivalent KS- men; and those with < 200 CD4 cells/mm3 had raised DHEA only compared with KS- men.	Potassium	4-6	CD4 molecule	Homo sapiens	165-168
7665693-5	1995	The KS+ patients with more than 500 CD4 lymphocytes per mm3 had significantly higher serum DHEA, DHEA sulphate, and testosterone than the KS- patients with the same CD4 counts; those with 500-200 CD4 cells/mm3 had higher serum DHEA and testosterone than the equivalent KS- men; and those with < 200 CD4 cells/mm3 had raised DHEA only compared with KS- men.	Potassium	4-6	CD4 molecule	Homo sapiens	165-168
7473515-1	1995	The renin-angiotensin-aldosterone hormonal servo-control system plays a major role in defending normotension and sodium and potassium balance.	Potassium	124-133	renin	Homo sapiens	4-9
7760061-1	1995	The adenosine A2a receptor inhibition of potassium (15 mM)-evoked GABA release from striatal nerve terminals has been examined.	Potassium	41-50	adenosine A2a receptor	Homo sapiens	4-26
7651611-0	1995	Potassium currents in isolated CA1 neurons of the rat after kindling epileptogenesis.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	31-34
7786304-4	1995	Carbachol (1 mM) and potassium (100 mM) caused a time (T1/2 = 3 and 4 min, respectively) and dose (EC50 = 6.95 microM and 34.7 mM respectively) related increase in cAMP formation.	Potassium	21-30	CD5 molecule	Homo sapiens	55-69
7669262-5	1995	An increase in serum potassium levels may occur after coadministration of potassium-sparing diuretics and ACE inhibitors, resulting in hyperkalaemia especially in patients with renal insufficiency.	Potassium	21-30	angiotensin I converting enzyme	Homo sapiens	106-109
7752097-0	1995	Kappa opioid receptor-mediated suppression of voltage-activated potassium current in a catecholaminergic neuronal cell line.	Potassium	64-73	opioid receptor kappa 1	Homo sapiens	0-21
7603774-6	1995	In vivo, growth hormone induced a rapid increase in the absorption rates of water, sodium, chloride, and potassium.	Potassium	105-114	gonadotropin releasing hormone receptor	Rattus norvegicus	9-23
7646841-9	1995	Likewise, in the human coronary artery, the hyperpolarization elicited by bradykinin, which is also mediated by EDHF, is augmented in the presence of perindoprilat and prevented by potassium-induced depolarization.	Potassium	181-190	kininogen 1	Homo sapiens	74-84
7752079-5	1995	At this dose, Ang II produced significant decreases in glomerular filtration rate (GFR), filtration fraction (FF), urine volume (UV) and urinary excretion of sodium (UNaV) and potassium (UkV) in SHR without altering any of these parameters in WKY rats.	Potassium	176-185	angiotensinogen	Rattus norvegicus	14-20
8646567-5	1995	Since high-potassium-induced release of CRF is probably due to opening of voltage-dependent calcium channels, it is likely that IL-2 is releasing CRF by this mechanism.	Potassium	11-20	interleukin 2	Rattus norvegicus	128-132
7733313-9	1995	We conclude that one function of the maxi K channel located in the apical membrane of the rat CCT may be to release intracellular solute (potassium) during a volume regulatory decrease induced by placing a dilute solution on the basolateral surface or when the apical osmolarity is reduced in the presence of vasopressin.	Potassium	138-147	arginine vasopressin	Rattus norvegicus	309-320
7737113-0	1995	Potassium-inhibited processing of IL-1 beta in human monocytes.	Potassium	0-9	interleukin 1 beta	Homo sapiens	34-43
7652188-2	1995	A decrease in potassium conductance may depolarize the plasma membrane, activating calcium channels with a resultant stimulation in CCK release.	Potassium	14-23	cholecystokinin	Homo sapiens	132-135
7703232-8	1995	The average dissociation constants Ks were 3.4 and 20.2 microM for MB-COMT and S-COMT, respectively.	Potassium	35-37	catechol-O-methyltransferase	Homo sapiens	70-74
7703232-8	1995	The average dissociation constants Ks were 3.4 and 20.2 microM for MB-COMT and S-COMT, respectively.	Potassium	35-37	catechol-O-methyltransferase	Homo sapiens	81-85
7724613-1	1995	Kaliuretic peptide, a new peptide hormone consisting of amino acids 79-98 of the 126 amino acid atrial natriuretic factor (ANF) prohormone, is synthesized in the heart and is a potent stimulator of potassium excretion.	Potassium	198-207	natriuretic peptide A	Homo sapiens	123-126
7796112-10	1995	This was demonstrated by the finding that the upregulation in GFAP mRNA induced by the potassium exposure was totally blocked by prior administration of MK-801, an NMDA antagonist that blocks spreading depression.	Potassium	87-96	glial fibrillary acidic protein	Homo sapiens	62-66
7733984-0	1995	Inhibition of angiotensin II- and potassium-mediated aldosterone secretion by KN-62 suggests involvement of Ca(2+)-calmodulin dependent protein kinase II in aldosterone secretion.	Potassium	34-43	calmodulin 1	Homo sapiens	115-125
7733984-3	1995	We have shown here that calmodulin-dependent kinase II is involved in angiotensin II- and potassium-evoked aldosterone secretion as judged by the marked inhibitory effect of KN-62, a specific inhibitor of such a kinase, on aldosterone secretion and this inhibition was similar to that produced by calmodulin inhibitor, W-7.	Potassium	90-99	calmodulin 1	Homo sapiens	24-34
7733984-3	1995	We have shown here that calmodulin-dependent kinase II is involved in angiotensin II- and potassium-evoked aldosterone secretion as judged by the marked inhibitory effect of KN-62, a specific inhibitor of such a kinase, on aldosterone secretion and this inhibition was similar to that produced by calmodulin inhibitor, W-7.	Potassium	90-99	calmodulin 1	Homo sapiens	297-307
7897237-4	1995	Here we show that AIDS-KS cells constitutively produce and release bioactive bFGF in the absence of cell death, and that extracellular bFGF exist in both a soluble and a bound form; the latter can be released by treatment with trypsin, heparin, or heparinase I.	Potassium	23-25	fibroblast growth factor 2	Homo sapiens	77-81
7897237-5	1995	Inflammatory cytokines stimulate both the synthesis and release of biologically active bFGF from KS cells and enhance their ability to induce angiogenic KS-like lesions in nude mice.	Potassium	97-99	fibroblast growth factor 2	Mus musculus	87-91
7897237-6	1995	Because bFGF is highly expressed in primary KS lesions, and is a mediator of KS-like lesion formation, these results suggest that the export of bFGF induced by inflammatory cytokines may play a critical role in the induction and progression of KS in HIV-1-infected homosexual men.	Potassium	44-46	fibroblast growth factor 2	Mus musculus	8-12
7897237-6	1995	Because bFGF is highly expressed in primary KS lesions, and is a mediator of KS-like lesion formation, these results suggest that the export of bFGF induced by inflammatory cytokines may play a critical role in the induction and progression of KS in HIV-1-infected homosexual men.	Potassium	44-46	fibroblast growth factor 2	Mus musculus	144-148
7897237-6	1995	Because bFGF is highly expressed in primary KS lesions, and is a mediator of KS-like lesion formation, these results suggest that the export of bFGF induced by inflammatory cytokines may play a critical role in the induction and progression of KS in HIV-1-infected homosexual men.	Potassium	77-79	fibroblast growth factor 2	Mus musculus	8-12
7897237-6	1995	Because bFGF is highly expressed in primary KS lesions, and is a mediator of KS-like lesion formation, these results suggest that the export of bFGF induced by inflammatory cytokines may play a critical role in the induction and progression of KS in HIV-1-infected homosexual men.	Potassium	77-79	fibroblast growth factor 2	Mus musculus	144-148
7714460-8	1995	The plasma potassium level was negatively correlated to plasma aldosterone (r = -0.57; P < 0.01) and renin activity (r = -0.69; P < 0.001).	Potassium	11-20	renin	Homo sapiens	104-109
7890648-3	1995	Results from classic depolarizing stimuli, high potassium (30-140 mM) and 1,1-dimethyl-4-phenylpiperazinium (3-50 microM), show a dependence of peak cytosolic Ca2+ concentration and catecholamine release on secretagogue concentration.	Potassium	48-57	carbonic anhydrase 2	Bos taurus	159-162
8847943-4	1995	Ritodrine and salbutamol significantly increased plasma cyclic AMP and decreased serum potassium concentrations indicating the presence of beta 2-adrenoceptor stimulation.	Potassium	87-96	adrenoceptor beta 2	Homo sapiens	139-158
7892240-4	1995	SytIV mRNA accumulation is transiently induced in PC12 cells by potassium depolarization, calcium ionophore, ATP, and forskolin.	Potassium	64-73	synaptotagmin 4	Rattus norvegicus	0-5
7892273-1	1995	The TRK2 gene in Saccharomyces cerevisiae encodes a membrane protein involved in potassium transport and is expressed at extremely low levels.	Potassium	81-90	Trk2p	Saccharomyces cerevisiae S288C	4-8
7900841-2	1995	Infusions of ANF caused a significantly greater increase in urinary excretion of fluid, sodium, and potassium in virgin than in pregnant (13-15 days and 21 days) rats.	Potassium	100-109	natriuretic peptide A	Rattus norvegicus	13-16
7836457-0	1995	How potassium affects the activity of the molecular chaperone Hsc70.	Potassium	4-13	heat shock protein family A (Hsp70) member 8	Homo sapiens	62-67
7900835-3	1995	The kidney H(+)-K(+)-ATPase protein(s) contribute to potassium reabsorption and secretion of hydrogen ions to maintain potassium and acid-base homeostasis.	Potassium	53-62	ATPase, H+/K+ exchanging, beta polypeptide	Mus musculus	11-27
7900835-3	1995	The kidney H(+)-K(+)-ATPase protein(s) contribute to potassium reabsorption and secretion of hydrogen ions to maintain potassium and acid-base homeostasis.	Potassium	119-128	ATPase, H+/K+ exchanging, beta polypeptide	Mus musculus	11-27
7900835-9	1995	Overall, these data indicate that the gastric H(+)-K(+)-ATPase beta-subunit is found in the kidney and probably associates with the gastric H(+)-K(+)-ATPase alpha-subunit and/or other P-type ATPase alpha-subunits, thus contributing to acid-base and potassium homeostasis.	Potassium	249-258	ATPase, H+/K+ exchanging, beta polypeptide	Mus musculus	46-62
7900835-9	1995	Overall, these data indicate that the gastric H(+)-K(+)-ATPase beta-subunit is found in the kidney and probably associates with the gastric H(+)-K(+)-ATPase alpha-subunit and/or other P-type ATPase alpha-subunits, thus contributing to acid-base and potassium homeostasis.	Potassium	249-258	ATPase, H+/K+ exchanging, beta polypeptide	Mus musculus	140-156
8520522-5	1995	Interestingly, the reduction in serum potassium levels during the ITT was also lower in the patients than in the controls (0.6 +/- 0.06 mEq/l vs 1.06 +/- 0.07 mEq/l, P < 0.05), suggesting that the insulin resistance observed in psoriasis is not only related to glucose metabolism, but also to another important action of insulin, namely extrarenal potassium homeostasis.	Potassium	38-47	insulin	Homo sapiens	200-207
8520522-5	1995	Interestingly, the reduction in serum potassium levels during the ITT was also lower in the patients than in the controls (0.6 +/- 0.06 mEq/l vs 1.06 +/- 0.07 mEq/l, P < 0.05), suggesting that the insulin resistance observed in psoriasis is not only related to glucose metabolism, but also to another important action of insulin, namely extrarenal potassium homeostasis.	Potassium	38-47	insulin	Homo sapiens	324-331
7900906-5	1995	Potassium uptake rate (KUR; mumol K+.g wet wt-1.min-1) was also measured (as 86Rb+ uptake) and was also lower in larger mammals, yielding the equations KUR = 1.2 M-0.14 in liver slices and KUR = 3.4 M-0.13 for kidney cortex slices.	Potassium	0-9	cilia and flagella associated protein 298	Homo sapiens	23-26
7900906-5	1995	Potassium uptake rate (KUR; mumol K+.g wet wt-1.min-1) was also measured (as 86Rb+ uptake) and was also lower in larger mammals, yielding the equations KUR = 1.2 M-0.14 in liver slices and KUR = 3.4 M-0.13 for kidney cortex slices.	Potassium	0-9	cilia and flagella associated protein 298	Homo sapiens	152-155
7900906-5	1995	Potassium uptake rate (KUR; mumol K+.g wet wt-1.min-1) was also measured (as 86Rb+ uptake) and was also lower in larger mammals, yielding the equations KUR = 1.2 M-0.14 in liver slices and KUR = 3.4 M-0.13 for kidney cortex slices.	Potassium	0-9	cilia and flagella associated protein 298	Homo sapiens	152-155
7790611-2	1995	We refer to a patient with a brain stem compression after head injury, who developed a profound hypokalemia (K+ = 1.2 mmol/l) with life-threatening arrhythmias, probably due to a catecholamine induced intracellular potassium shift (beta-2-stimulation).	Potassium	215-224	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	232-238
7891132-0	1995	Genetic analysis of Drosophila neurons: Shal, Shaw, and Shab encode most embryonic potassium currents.	Potassium	83-92	Shaker cognate l	Drosophila melanogaster	40-44
7891132-0	1995	Genetic analysis of Drosophila neurons: Shal, Shaw, and Shab encode most embryonic potassium currents.	Potassium	83-92	Shaker cognate w	Drosophila melanogaster	46-50
7891132-0	1995	Genetic analysis of Drosophila neurons: Shal, Shaw, and Shab encode most embryonic potassium currents.	Potassium	83-92	Shaker cognate b	Drosophila melanogaster	56-60
7836457-2	1995	Potassium is required for optimal ATPase activity.	Potassium	0-9	dynein axonemal heavy chain 8	Homo sapiens	34-40
7836457-3	1995	Several functions of the 70-kilodalton heat shock cognate protein (Hsc70), such as peptide binding/release and clathrin uncoating, have been shown to require potassium ions.	Potassium	158-167	heat shock protein family A (Hsp70) member 8	Homo sapiens	67-72
7847370-3	1995	HypoPP is characterized by acute attacks of muscle weakness concomitant with a fall in blood potassium levels.	Potassium	93-102	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	0-6
7864190-1	1995	Although it has long been established that cerebrospinal fluid potassium concentration (CSF [K]) is very tightly regulated, it has been reported that rats made hypertensive by central infusions of aldosterone have significantly lower CSF [K] compared with normotensive controls.	Potassium	63-72	colony stimulating factor 2	Rattus norvegicus	88-91
7821278-0	1995	Effects of glutamate, N-methyl-D-aspartate, high potassium, and hypoxia on unit discharges in CA1 area of hippocampal slices of DBA and C57 mice.	Potassium	49-58	carbonic anhydrase 1	Mus musculus	94-97
7836458-3	1995	Crystallographic anomalous scattering from potassium at 1.7 A resolution reveals two monovalent ions that interact with MgADP and P(i) in the nucleotide binding cleft of wild-type recombinant bovine Hsc70 ATPase fragment.	Potassium	43-52	heat shock protein family A (Hsp70) member 8	Bos taurus	199-204
7836458-0	1995	How potassium affects the activity of the molecular chaperone Hsc70.	Potassium	4-13	heat shock protein family A (Hsp70) member 8	Bos taurus	62-67
7724045-0	1995	Protein kinase C mediates neurotensin inhibition of inwardly rectifying potassium currents in rat substantia nigra dopaminergic neurons.	Potassium	72-81	protein kinase C, gamma	Rattus norvegicus	0-16
7843274-0	1995	Fibronectin receptor internalization and AP-2 complex reorganization in potassium-depleted fibroblasts.	Potassium	72-81	fibronectin 1	Homo sapiens	0-11
7843274-0	1995	Fibronectin receptor internalization and AP-2 complex reorganization in potassium-depleted fibroblasts.	Potassium	72-81	transcription factor AP-2 alpha	Homo sapiens	41-45
7843274-4	1995	Potassium-depleted fibroblasts endocytosed antibody-tagged FNR and also internalized fluorescent fibronectin that previously had been adsorbed to the substratum.	Potassium	0-9	fibronectin 1	Homo sapiens	97-108
7843274-6	1995	Plasma membrane AP-2 complexes, which were undetectable in potassium-depleted cells, reappeared at the cell surface above the nucleus and then spread toward the cell margins.	Potassium	59-68	transcription factor AP-2 alpha	Homo sapiens	16-20
7724045-6	1995	Dialyzing DA neurons with protein kinase C (PKC) inhibitors, staurosporine and PKC(19-31), prevented neurotensin from decreasing the potassium conductance.	Potassium	133-142	protein kinase C, gamma	Rattus norvegicus	26-42
7724045-0	1995	Protein kinase C mediates neurotensin inhibition of inwardly rectifying potassium currents in rat substantia nigra dopaminergic neurons.	Potassium	72-81	neurotensin	Rattus norvegicus	26-37
7724045-6	1995	Dialyzing DA neurons with protein kinase C (PKC) inhibitors, staurosporine and PKC(19-31), prevented neurotensin from decreasing the potassium conductance.	Potassium	133-142	protein kinase C, gamma	Rattus norvegicus	44-47
7724045-6	1995	Dialyzing DA neurons with protein kinase C (PKC) inhibitors, staurosporine and PKC(19-31), prevented neurotensin from decreasing the potassium conductance.	Potassium	133-142	protein kinase C, gamma	Rattus norvegicus	79-82
7724045-1	1995	Whole-cell voltage-clamp recordings were used to investigate the molecular transduction mechanism by which neurotensin decreases the inwardly rectifying potassium conductance of dopaminergic (DA) neurons acutely isolated from the rat substantia nigra (SN).	Potassium	153-162	neurotensin	Rattus norvegicus	107-118
7724045-6	1995	Dialyzing DA neurons with protein kinase C (PKC) inhibitors, staurosporine and PKC(19-31), prevented neurotensin from decreasing the potassium conductance.	Potassium	133-142	neurotensin	Rattus norvegicus	101-112
7835694-0	1995	Expression of a putative ATPase suppresses the growth defect of a yeast potassium transport mutant: identification of a mammalian member of the Clp/HSP104 family.	Potassium	72-81	calmodulin like 3	Homo sapiens	144-147
7724045-7	1995	Our results propose that neurotensin activates PKC of SN DA neurons via PTX-insensitive G-proteins and that PKC mediates the neurotensin inhibition of inwardly rectifying potassium currents.	Potassium	171-180	protein kinase C, gamma	Rattus norvegicus	108-111
7724045-7	1995	Our results propose that neurotensin activates PKC of SN DA neurons via PTX-insensitive G-proteins and that PKC mediates the neurotensin inhibition of inwardly rectifying potassium currents.	Potassium	171-180	neurotensin	Rattus norvegicus	125-136
7751417-0	1995	Selected aspects of ACE inhibitor therapy for patients with renal disease: impact on proteinuria, lipids and potassium.	Potassium	109-118	angiotensin I converting enzyme	Homo sapiens	20-23
8582318-1	1995	We have investigated the electrophysiological basis of potassium inward rectification of the KAT1 gene product from Arabidopsis thaliana expressed in Xenopus oocytes and of functionally related K+ channels in the plasma membrane of guard and root cells from Vicia faba and Zea mays.	Potassium	55-64	1	Arabidopsis thaliana	93-97
7798924-12	1995	Potassium stimulation led to increased Asp, Glu, Gly, and Tau levels, whereas Gln content decreased and Ser remained unaltered.	Potassium	0-9	microtubule associated protein tau	Homo sapiens	58-61
7529828-4	1995	Using whole-cell, perforated-patch, and single-channel recording, we found that treatment with NGF increased levels of voltage-gated sodium, calcium, and potassium currents.	Potassium	154-163	nerve growth factor	Homo sapiens	95-98
7529828-5	1995	In contrast, CNTF treatment increased levels of potassium currents only.	Potassium	48-57	ciliary neurotrophic factor	Homo sapiens	13-17
16031800-3	1995	A severe cyclonic disturbance in early 1988, Cyclone Bola, was associated with changes in pasture sodium, potassium and magnesium, urinary sodium, and serum magnesium concentrations.	Potassium	106-115	MHC class I antigen clone 2	Bos taurus	53-57
7793316-3	1995	In this review we propose that aberrant expression SF and c-met is central to the pathogenesis of KS.	Potassium	98-100	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	58-63
7793316-13	1995	We believe, however, that recognition of SF/c-met as a participant in this disease is necessary if we are to more fully understand the pathogenesis of AIDS-associated KS.	Potassium	167-169	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	44-49
7600450-0	1995	Changes of activation and inactivation gating of the transient potassium current of rat pituitary melanotrophs caused by micromolar Cd2+ and Zn2+.	Potassium	63-72	Cd2 molecule	Rattus norvegicus	132-135
7529828-6	1995	NGF and CNTF appeared to regulate the same delayed-rectifier potassium current; in addition, NGF treatment resulted in increased levels of a second potassium current component.	Potassium	61-70	nerve growth factor	Homo sapiens	0-3
7529828-6	1995	NGF and CNTF appeared to regulate the same delayed-rectifier potassium current; in addition, NGF treatment resulted in increased levels of a second potassium current component.	Potassium	61-70	ciliary neurotrophic factor	Homo sapiens	8-12
8696309-6	1995	By using slice patch-clamp techniques, AII inhibited the transient outward potassium current in the SON neurons.	Potassium	75-84	angiotensinogen	Rattus norvegicus	39-42
8538827-5	1995	A significant decrease in the fractional excretion of sodium, potassium, and phosphate was observed during the last 90 min of the IGF-I infusion period.	Potassium	62-71	insulin like growth factor 1	Homo sapiens	130-135
8538827-8	1995	IGF-I also enhances potassium and phosphate uptake by extrarenal tissues and reduces renal potassium and phosphate excretion.	Potassium	20-29	insulin like growth factor 1	Homo sapiens	0-5
8538827-8	1995	IGF-I also enhances potassium and phosphate uptake by extrarenal tissues and reduces renal potassium and phosphate excretion.	Potassium	91-100	insulin like growth factor 1	Homo sapiens	0-5
7830499-5	1995	Adrenomedullin dose dependently inhibited aldosterone secretion stimulated by 10(-9) M angiotensin II and 10 mM potassium, whereas 10(-9) M ACTH-stimulated aldosterone was not significantly inhibited by adrenomedullin.	Potassium	112-121	adrenomedullin	Rattus norvegicus	0-14
7535902-6	1995	By contrast, an outward potassium current was observed on 71 of 95 granulocyte/macrophage colony-stimulating factor-grown cells.	Potassium	24-33	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	67-115
7535902-10	1995	In such resting microglia a short-term treatment with granulocyte/macrophage colony-stimulating factor or interferon-gamma provoked a strong appearance of outward potassium currents, however, only the interferon-gamma-trigger resulted in efficient antigen presentation.	Potassium	163-172	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	54-102
7535902-10	1995	In such resting microglia a short-term treatment with granulocyte/macrophage colony-stimulating factor or interferon-gamma provoked a strong appearance of outward potassium currents, however, only the interferon-gamma-trigger resulted in efficient antigen presentation.	Potassium	163-172	interferon gamma	Mus musculus	106-122
7535902-10	1995	In such resting microglia a short-term treatment with granulocyte/macrophage colony-stimulating factor or interferon-gamma provoked a strong appearance of outward potassium currents, however, only the interferon-gamma-trigger resulted in efficient antigen presentation.	Potassium	163-172	interferon gamma	Mus musculus	201-217
7697882-0	1994	Potassium currents in acutely isolated maturing rat hippocampal CA1 neurones.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	64-67
7697882-1	1994	Whole-cell voltage clamp techniques were used to characterize the postnatal development of current amplitude and inactivation and activation kinetics of two potassium currents in acutely isolated CA1 cells from rats P4 to P52: the A-current (IA) and a slow-rising, slow inactivating current (IK).	Potassium	157-166	carbonic anhydrase 1	Rattus norvegicus	196-199
7716276-4	1994	Results showed that ANG II decreased bile flow and the excretion of sodium, potassium, chloride and bile acids whereas it increased pH, bile osmolality and the excretion rate of bicarbonate and calcium.	Potassium	76-85	angiotensinogen	Rattus norvegicus	20-26
7882030-5	1994	Basal, potassium-stimulated and NMDA-stimulated release of nitric oxide products were significantly inhibited by the NMDA-receptor antagonist D(-)-2-amino-5-phosphopentanoic acid (AP5) at 10(-4) M and by the NMDA-channel blocker ketamine at 10(-4) M. We conclude that nitric oxide mediates the stimulatory action of glutamic acid on the release of alpha-MSH from the rat hypothalamus.	Potassium	7-16	proopiomelanocortin	Rattus norvegicus	348-357
7881352-11	1994	The potassium elevation was treated successfully with hyperventilation, calcium chloride, sodium bicarbonate, glucose, and insulin.	Potassium	4-13	insulin	Homo sapiens	123-130
7961651-5	1994	E. coli flavodoxin binds P450c17 directly and with relatively high affinity (apparent Ks approximately 0.2 microM) at low ionic strength, as evidenced by a change in spin state of the P450c17 heme iron upon titration with flavodoxin.	Potassium	86-88	steroid 17-alpha-hydroxylase/17,20 lyase	Bos taurus	25-32
7858862-0	1994	Neuropeptide Y inhibits potassium-stimulated glutamate release through Y2 receptors in rat hippocampal slices in vitro.	Potassium	24-33	neuropeptide Y	Rattus norvegicus	0-14
7895068-0	1994	Nerve growth factor treatment induces high-potassium-evoked calcium-dependent acetylcholine release in cultured embryonic rat septal cells.	Potassium	43-52	nerve growth factor	Rattus norvegicus	0-19
7895068-3	1994	High-potassium-evoked ACh release was observed in NGF-treated cells but not in untreated and dbcAMP-treated cells.	Potassium	5-14	nerve growth factor	Rattus norvegicus	50-53
7982958-0	1994	Conformation-dependent phosphorylation of Na,K-ATPase by protein kinase A and protein kinase C. Phosphorylation of sodium and potassium ion-activated adenosine triphosphatase (Na,K-ATPase) by protein kinase A (PKA) and protein kinase C (PKC) was investigated in vitro, where substrate conformation, kinase activity, and consequent effects on Na,K-ATPase activity could be controlled.	Potassium	126-135	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	57-73
7982958-0	1994	Conformation-dependent phosphorylation of Na,K-ATPase by protein kinase A and protein kinase C. Phosphorylation of sodium and potassium ion-activated adenosine triphosphatase (Na,K-ATPase) by protein kinase A (PKA) and protein kinase C (PKC) was investigated in vitro, where substrate conformation, kinase activity, and consequent effects on Na,K-ATPase activity could be controlled.	Potassium	126-135	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	192-208
7982958-0	1994	Conformation-dependent phosphorylation of Na,K-ATPase by protein kinase A and protein kinase C. Phosphorylation of sodium and potassium ion-activated adenosine triphosphatase (Na,K-ATPase) by protein kinase A (PKA) and protein kinase C (PKC) was investigated in vitro, where substrate conformation, kinase activity, and consequent effects on Na,K-ATPase activity could be controlled.	Potassium	126-135	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	210-213
7706397-8	1994	When internalization via coated pits was inhibited by two different methods, potassium depletion and cytosol acidification, endocytosis of IL2 and its receptors was only partly inhibited, while transferrin entry was strongly affected.	Potassium	77-86	interleukin 2	Homo sapiens	139-142
7898749-1	1994	We demonstrate in PC12 cells that although nerve growth factor, forskolin or potassium-evoked depolarisation independently induced minimal or no expression from the rat preprotachykinin-A gene (rPPT) promoter linked to a reporter gene, exposure of the cells to various combinations of these stimuli specifically activated the rPPT promoter in transient transfection assays.	Potassium	77-86	tachykinin, precursor 1	Rattus norvegicus	326-330
7767869-2	1994	The injection of endothelin-1 (1 nmol/kg body weight) induced a sharp and transient decrease in urine flow, sodium and potassium excretion, glomerular filtration rate, renal plasma flow, and renal blood flow, a significant increase in renal vascular resistance, and a small but significant increase in arterial pressure.	Potassium	119-128	endothelin 1	Rattus norvegicus	17-29
7937077-1	1994	The rat HBP1 cDNA was cloned by its capacity to suppress the potassium transport-defective phenotype of mutant Saccharomyces cerevisiae cells.	Potassium	61-70	HMG-box transcription factor 1	Rattus norvegicus	8-12
7855730-0	1994	Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro.	Potassium	68-77	carbonic anhydrase 3	Cavia porcellus	101-104
7820067-7	1994	Application of potassium ions (60 mM) or veratridine (100 microM) both evoked release of AChE in control animals: however, when expressed as a percentage of basal levels, this increase in release was not influenced by drug treatment or state of consciousness.	Potassium	15-24	acetylcholinesterase	Cavia porcellus	89-93
7813050-4	1994	Comparison of sustained potassium current during postnatal development showed a significant increase in current amplitude with age reaching a peak between P20 and P30.	Potassium	24-33	heat shock protein family B (small) member 6	Rattus norvegicus	155-158
7957868-0	1994	Changes in activation gating of IsK potassium currents brought about by mutations in the transmembrane sequence.	Potassium	36-45	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	32-35
7824079-7	1994	Furthermore, the opioid peptide [D-Pro10]Dynorphin(1-11) which acts via the kappa opioid receptor, significantly inhibited basal and potassium-stimulated AVP secretion, an effect which was abolished when cells were cultured in the presence of cortisol.	Potassium	133-142	kappa-type opioid receptor	Ovis aries	76-97
7943248-5	1994	CGRP activation of potassium currents was prevented by dialysis of the cell cytoplasm with guanosine 5"-O-(2-thiodiphosphate) (5 mM) or a specific peptide inhibitor of protein kinase A (2.3 microM).	Potassium	19-28	calcitonin related polypeptide alpha	Homo sapiens	0-4
7882162-1	1994	The elastin-laminin receptor was shown to be present on several benign and malignant cell types and to mediate several important cell reactions such as chemotactic movements of fibroblasts and monocytes, release of lytic enzymes and oxygen free radicals from leucocytes, increased adhesion of mesenchymal cells to elastin fibers as well as modifications of ion fluxes-increase of calcium and sodium influxes and decrease of ouabain-dependent potassium influx.	Potassium	442-451	elastin	Rattus norvegicus	4-11
7860419-3	1994	The mechanism of action of VIP on corporal relaxation was investigated with respect to the activation of cyclic GMP and the mobilization of calcium and potassium ions.	Potassium	152-161	VIP peptides	Oryctolagus cuniculus	27-30
7860419-10	1994	In calcium-free high-potassium physiologic salt solution, VIP inhibited the calcium-induced contraction.	Potassium	21-30	VIP peptides	Oryctolagus cuniculus	58-61
7836703-5	1994	The effect of serum prolactin elevation on renal sodium and potassium excretion was studied in all patients after thyrotropin-releasing hormone stimulation (200 micrograms), with seven consecutive hourly urinary samples.	Potassium	60-69	prolactin	Homo sapiens	20-29
7985807-4	1994	In addition, measurements of the ks of MHC in skeletal muscle of rats in vivo using radioisotope-tracer methodologies are described.	Potassium	33-35	major histocompatibility complex, class I, C	Homo sapiens	39-42
7811548-2	1994	In this study we show that AIDS-KS cells express approximately 1100 high-affinity IL-6 receptors (IL-6R) per cell with a dissociation constant (Kd) of 110 pM.	Potassium	32-34	interleukin 6 receptor	Homo sapiens	82-96
7811548-2	1994	In this study we show that AIDS-KS cells express approximately 1100 high-affinity IL-6 receptors (IL-6R) per cell with a dissociation constant (Kd) of 110 pM.	Potassium	32-34	interleukin 6 receptor	Homo sapiens	98-103
7811548-3	1994	Furthermore, AIDS-KS cells express the IL-6R alpha subunit, detected as a single 5.0-kb messenger ribonucleic acid species, and the high-affinity converting, signal-transducing IL-6R beta subunit designated as gp130.	Potassium	18-20	interleukin 6 receptor	Homo sapiens	39-50
7811548-3	1994	Furthermore, AIDS-KS cells express the IL-6R alpha subunit, detected as a single 5.0-kb messenger ribonucleic acid species, and the high-affinity converting, signal-transducing IL-6R beta subunit designated as gp130.	Potassium	18-20	interleukin 6 cytokine family signal transducer	Homo sapiens	177-187
7811548-3	1994	Furthermore, AIDS-KS cells express the IL-6R alpha subunit, detected as a single 5.0-kb messenger ribonucleic acid species, and the high-affinity converting, signal-transducing IL-6R beta subunit designated as gp130.	Potassium	18-20	interleukin 6 cytokine family signal transducer	Homo sapiens	210-215
7811548-4	1994	Similarly, tumor tissue obtained from patients with KS and AIDS expresses IL-6R messenger ribonucleic acid.	Potassium	52-54	interleukin 6 receptor	Homo sapiens	74-79
7811548-7	1994	DAB389-IL-6 inhibited protein synthesis in AIDS-KS-derived spindle cells at very low concentrations (IC50 of 3.4 x 10(-11) M).	Potassium	48-50	interleukin 6	Homo sapiens	7-11
7811548-10	1994	Thus, DAB389-IL-6 is a potential agent for the treatment of AIDS-associated KS.	Potassium	76-78	interleukin 6	Homo sapiens	13-17
7874236-6	1994	Taken together, these data indicate that potassium-induced LTP may be related to modifications in both pre- and postsynaptic properties and confirm the hypothesis that PLA2 activation is an important mechanism in long-term changes of synaptic operation.	Potassium	41-50	phospholipase A2 group IB	Homo sapiens	168-172
7821363-4	1994	Infusion of adrenomedullin at the rates of 4 and 20 ng.kg-1.min-1 increased urine flow and the urinary excretion of sodium and potassium dose dependently.	Potassium	127-136	adrenomedullin	Canis lupus familiaris	12-26
8087923-9	1994	ProANFs 1-30, 31-67, 79-98, and ANF increased potassium excretion 2- to 3-fold, 0-fold, 3- to 4-fold, and 2-fold, respectively.	Potassium	46-55	natriuretic peptide A	Homo sapiens	3-6
7874236-0	1994	Potassium-induced long-term potentiation in area CA1 of the hippocampus involves phospholipase activation.	Potassium	0-9	carbonic anhydrase 1	Homo sapiens	49-52
7874236-1	1994	Previous studies have shown that potassium-induced long-term potentiation (LTP) of the Schaffer collateral/commissural synapses in area CA1 of the hippocampus shares common properties with tetanus-induced LTP.	Potassium	33-42	carbonic anhydrase 1	Homo sapiens	136-139
7874236-2	1994	In the present investigation, we performed electrophysiological and binding experiments on CA1 hippocampal slices to evaluate the location and nature of the changes underlying potassium-induced LTP.	Potassium	176-185	carbonic anhydrase 1	Homo sapiens	91-94
7874236-4	1994	In addition, KCl-induced LTP was associated with an increase in 3H-AMPA ([3H]-amino-3-hydroxy-5-methylisoxazole-4-propionate) binding to CA1 synaptic membranes when measured 40 min after high-potassium exposure; however, no changes were detected in binding of an antagonist ([3H]-6-cyano-7-nitroquinoxaline-2,3-dione; 3H-CNQX) to AMPA receptors in slices expressing KCl-induced LTP.	Potassium	192-201	carbonic anhydrase 1	Homo sapiens	137-140
7874236-5	1994	Administration of the phospholipase A2 (PLA2) inhibitor bromophenacyl bromide (BPB) prior to potassium application prevented LTP formation as well as the changes in paired-pulse facilitation and 3H-AMPA binding that characterized this type of potentiation.	Potassium	93-102	phospholipase A2 group IB	Homo sapiens	22-38
8045293-4	1994	The ATP1AL1 encoded protein was proposed to represent a new separate group within the family of human potassium-dependent ion pumps.	Potassium	102-111	ATPase H+/K+ transporting non-gastric alpha2 subunit	Homo sapiens	4-11
7526050-0	1994	Safety of concomitant potassium-sparing diuretics in angiotensin-converting enzyme inhibitor therapy in severe congestive heart failure.	Potassium	22-31	angiotensin I converting enzyme	Homo sapiens	53-82
7804607-0	1994	Modulation of expression of glucose transporters GLUT3 and GLUT1 by potassium and N-methyl-D-aspartate in cultured cerebellar granule neurons.	Potassium	68-77	solute carrier family 2 member 3	Homo sapiens	49-54
7804607-0	1994	Modulation of expression of glucose transporters GLUT3 and GLUT1 by potassium and N-methyl-D-aspartate in cultured cerebellar granule neurons.	Potassium	68-77	solute carrier family 2 member 1	Homo sapiens	59-64
8021011-3	1994	Reducing potassium concentration of endothelial cell media (normally 5.1 to 6.1 mmol/L) to 3.0 mmol/L exponentially increased the rate of cytochrome c reduction, up to 8.4-fold at 2 hours; raising potassium concentration to 5.5 or 7.0 mmol/L at 1 hour reduced the maximal rate of cytochrome c reduction by 86% or 93%.	Potassium	9-18	cytochrome c, somatic	Homo sapiens	138-150
7953702-0	1994	Involvement of a Ca2+/calmodulin-dependent protein kinase II-associated mechanism in the induction of an outward potassium current by quisqualate.	Potassium	113-122	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	17-60
7953702-5	1994	These results suggest a novel mechanism linked to CaMKII, by which quisqualate induces an outward potassium current.	Potassium	98-107	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	50-56
8021011-3	1994	Reducing potassium concentration of endothelial cell media (normally 5.1 to 6.1 mmol/L) to 3.0 mmol/L exponentially increased the rate of cytochrome c reduction, up to 8.4-fold at 2 hours; raising potassium concentration to 5.5 or 7.0 mmol/L at 1 hour reduced the maximal rate of cytochrome c reduction by 86% or 93%.	Potassium	9-18	cytochrome c, somatic	Homo sapiens	280-292
8021011-3	1994	Reducing potassium concentration of endothelial cell media (normally 5.1 to 6.1 mmol/L) to 3.0 mmol/L exponentially increased the rate of cytochrome c reduction, up to 8.4-fold at 2 hours; raising potassium concentration to 5.5 or 7.0 mmol/L at 1 hour reduced the maximal rate of cytochrome c reduction by 86% or 93%.	Potassium	197-206	cytochrome c, somatic	Homo sapiens	138-150
8021011-5	1994	Potassium reduced the rate of cytochrome c reduction by 49% (endothelial cells) to 55% (monocytes/macrophages) between 3.0 and 7.0 mmol/L; the greatest decrement (20% to 26%) occurred between 3.0 and 4.0 mmol/L.	Potassium	0-9	cytochrome c, somatic	Homo sapiens	30-42
8021238-4	1994	In addition, deletion of the cytoplasmic domains of beta PP or depletion of potassium in medium, both of which resulted in reduced beta PP internalization, significantly diminished A beta release.	Potassium	76-85	amyloid beta precursor protein	Homo sapiens	181-187
7958155-7	1994	Furthermore, there was a significant positive relationship between ET-1 excretion and urine flow rate (r = 0.67, P < 0.0001), CCR (r = 0.40, P < 0.0025), Cosm (r = 0.58, P < 0.001), sodium (r = 0.56, P < 0.001) and potassium excretion (r = 0.42, P < 0.001).	Potassium	227-236	endothelin 1	Homo sapiens	67-71
7969755-5	1994	Potassium stimulated TRH release from olfactory bulb was not different from basal release at any time.	Potassium	0-9	thyrotropin releasing hormone	Rattus norvegicus	21-24
7919903-1	1994	OBJECTIVE: The goal of this study was to examine the metabolic and hemodynamic effects of a glucose-insulin-potassium infusion in elective coronary surgery, when blood cardioplegia was used for cardiac protection.	Potassium	108-117	insulin	Homo sapiens	100-107
8013643-4	1994	Xenopus oocytes injected with cRNA derived from this clone expressed a potassium current which showed inward-rectifying channel characteristics similar to MB-IRK1 and RB-IRK2 currents, but distinct from ROMK1 or GIRK1 current.	Potassium	71-80	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	158-162
11362144-0	1994	Interleukin-4 tried for KS.	Potassium	24-26	interleukin 4	Homo sapiens	0-13
8206564-8	1994	After treatment, intracellular potassium and magnesium were both associated with higher serum insulin (P < .001 for each), and serum potassium was associated with higher and serum magnesium with lower serum glucose (P < .01 for each).	Potassium	31-40	insulin	Homo sapiens	94-101
8189223-8	1994	Neurons deprived of NGF gradually lost the ability to respond to elevated external potassium with an increase in [Ca2+]i during the first 24 h after trophic factor deprivation.	Potassium	83-92	nerve growth factor	Rattus norvegicus	20-23
7921529-6	1994	Both beta 2-agonists significantly decreased plasma potassium.	Potassium	52-61	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	5-11
8189249-3	1994	At the presynaptic level, neuropeptide Y inhibits by 45%, with an EC50 of 50 nM, the potassium-evoked noradrenaline release from pineal nerve endings.	Potassium	85-94	neuropeptide Y	Rattus norvegicus	26-40
8014882-7	1994	In addition, the muscles from GH-treated aged rats had values of potassium conductance completely restored down to the adult ones.	Potassium	65-74	gonadotropin releasing hormone receptor	Rattus norvegicus	30-32
7912276-8	1994	High extracellular potassium concentrations or carbachol evoked release of endogenous VIP.	Potassium	19-28	VIP peptides	Cavia porcellus	86-89
7931509-0	1994	5-HT1A receptor linked to inward-rectifying potassium current in hippocampal CA3 pyramidal cells.	Potassium	44-53	5-hydroxytryptamine receptor 1A	Rattus norvegicus	0-6
7931509-0	1994	5-HT1A receptor linked to inward-rectifying potassium current in hippocampal CA3 pyramidal cells.	Potassium	44-53	carbonic anhydrase 3	Rattus norvegicus	77-80
7931509-18	1994	On the basis of these results, we conclude that 5-HT hyperpolarized hippocampal CA3 pyramidal cells by increasing an inward-rectifying potassium conductance.	Potassium	135-144	carbonic anhydrase 3	Rattus norvegicus	80-83
8195155-13	1994	ADP was less active than ATP at initiating the post-translational maturation and release of IL-1 beta and AMP, GTP, and UTP were totally inactive, ATP, nigericin, A204, and lasalocid promoted a rapid and complete loss of the potassium analog 86Rb+ from cells that were preloaded with this cation; valinomycin-treated cells released only a portion of the radiolabeled cation.	Potassium	225-234	interleukin 1 beta	Mus musculus	92-101
7938088-0	1994	Interactions between the renin-angiotensin system and prostanoids in modulating renal function in potassium-depleted healthy women.	Potassium	98-107	renin	Homo sapiens	25-30
7911016-4	1994	In vivo expression analysis showed that HCT10 encoded potassium-ion non-activated acetoacetyl-CoA thiolase with no 3-ketooctanoyl-CoA thiolase activity, which is characteristic for CT.	Potassium	54-63	acetyl-CoA acetyltransferase 1	Homo sapiens	82-106
7911016-4	1994	In vivo expression analysis showed that HCT10 encoded potassium-ion non-activated acetoacetyl-CoA thiolase with no 3-ketooctanoyl-CoA thiolase activity, which is characteristic for CT.	Potassium	54-63	acetyl-CoA acetyltransferase 1	Homo sapiens	41-43
8182084-3	1994	In PC-12 cells, potassium-induced membrane depolarization increased expression of a CRH-reporter construct in a cAMP-dependent manner.	Potassium	16-25	corticotropin releasing hormone	Rattus norvegicus	84-87
8182084-5	1994	RNase protection assays demonstrated increased levels of CRH-reporter transcripts in stably transfected cells after treatment with cAMP and potassium, with the induced transcripts initiating at the major transcription initiation site of the human CRH gene.	Potassium	140-149	corticotropin releasing hormone	Homo sapiens	57-60
8182084-5	1994	RNase protection assays demonstrated increased levels of CRH-reporter transcripts in stably transfected cells after treatment with cAMP and potassium, with the induced transcripts initiating at the major transcription initiation site of the human CRH gene.	Potassium	140-149	corticotropin releasing hormone	Homo sapiens	247-250
8195155-14	1994	Agents that promoted the maturation and release of IL-1 beta from LPS-stimulated macrophages, therefore, shared an ability to mobilize intracellular potassium.	Potassium	149-158	interleukin 1 beta	Mus musculus	51-60
8182084-7	1994	Additionally, DNase I protection assays demonstrated similar nuclear protein/DNA binding profiles across the cAMP-responsive element after treatment of PC-12 cells with potassium or potassium/cAMP.	Potassium	169-178	deoxyribonuclease 1	Rattus norvegicus	14-21
8182084-7	1994	Additionally, DNase I protection assays demonstrated similar nuclear protein/DNA binding profiles across the cAMP-responsive element after treatment of PC-12 cells with potassium or potassium/cAMP.	Potassium	182-191	deoxyribonuclease 1	Rattus norvegicus	14-21
7515565-0	1994	Atrial natriuretic peptide enhances activity of potassium conductance in adrenal glomerulosa cells.	Potassium	48-57	natriuretic peptide A	Homo sapiens	0-26
7489328-8	1994	Because activation of PLA2 requires an increase in intracellular calcium ion (Ca2+) concentrations, we evaluated the effect of alpha-MSH on the release of CRF induced by a high concentration of potassium (56 mM).	Potassium	194-203	proopiomelanocortin	Homo sapiens	127-136
8039040-17	1994	The reduction of potassium was significantly correlated with the elevation of insulin (i.v.	Potassium	17-26	insulin	Homo sapiens	78-85
7519198-2	1994	Substance P induced a significant relaxation in segments with intact endothelium pre-contracted by potassium or 5-hydroxytryptamine.	Potassium	99-108	tachykinin precursor 1	Homo sapiens	0-11
8137725-2	1994	To investigate the possibility that NPY exerts a modulatory role on the release of neurohypophysial hormones, we have studied the actions of NPY on potassium-evoked release of vasopressin and oxytocin from the rat neurointermediate lobe in vitro.	Potassium	148-157	arginine vasopressin	Rattus norvegicus	176-187
8137725-3	1994	NPY dose-dependently potentiated vasopressin release evoked by high extracellular potassium (56 mM), with a maximal enhancement of 223% (10(-7) M NPY).	Potassium	82-91	neuropeptide Y	Rattus norvegicus	0-3
8137725-3	1994	NPY dose-dependently potentiated vasopressin release evoked by high extracellular potassium (56 mM), with a maximal enhancement of 223% (10(-7) M NPY).	Potassium	82-91	arginine vasopressin	Rattus norvegicus	33-44
7516007-3	1994	ET-1, ET-2, and ET-3 induced significantly higher maximum contraction (measured in percentage of contraction induced by 60 mM potassium) and more potent responses in veins as compared with arteries.	Potassium	126-135	endothelin 1	Homo sapiens	0-4
7516007-3	1994	ET-1, ET-2, and ET-3 induced significantly higher maximum contraction (measured in percentage of contraction induced by 60 mM potassium) and more potent responses in veins as compared with arteries.	Potassium	126-135	endothelin 2	Homo sapiens	6-10
7516007-3	1994	ET-1, ET-2, and ET-3 induced significantly higher maximum contraction (measured in percentage of contraction induced by 60 mM potassium) and more potent responses in veins as compared with arteries.	Potassium	126-135	endothelin 3	Homo sapiens	16-20
8194069-7	1994	The Ks for beta-, alpha-, and gamma-CD determined in apple juice, which contains a mixture of PPO substrates, were found to correlate with PPO activity-related data.	Potassium	4-6	polyphenol oxidase, chloroplastic	Malus domestica	94-97
8137958-4	1994	Xenopus oocytes injected with cRNA derived from RB-IRK2 expressed a potassium current which showed inward-rectifying channel characteristics similar to the IRK1 current, but distinct from the ROMK1 or the GIRK1 currents.	Potassium	68-77	potassium inwardly-rectifying channel, subfamily J, member 12	Rattus norvegicus	51-55
8194069-7	1994	The Ks for beta-, alpha-, and gamma-CD determined in apple juice, which contains a mixture of PPO substrates, were found to correlate with PPO activity-related data.	Potassium	4-6	polyphenol oxidase, chloroplastic	Malus domestica	139-142
8047284-0	1994	Potassium efflux from infant and adult rat choroid plexuses: effects of CSF anion substitution, N-ethylmaleimide and Cl transport inhibitors.	Potassium	0-9	colony stimulating factor 2	Rattus norvegicus	72-75
8006915-5	1994	However potassium intake, prostaglandin and kallikrein excretions are low in blacks and black/white differences exist in the distribution of the restriction fragment length polymorphism at the gene loci for renin.	Potassium	8-17	renin	Homo sapiens	207-212
8011980-3	1994	The chronic administration of IL-2 (100,000 U/kg, thrice daily, ip) resulted in a significant increase in body weight, a decrease in GFR and in the urinary excretion of sodium and potassium, and an increase in the urinary excretion of thromboxane (TXB2).	Potassium	180-189	interleukin 2	Rattus norvegicus	30-34
7907136-0	1994	Effect of potassium-induced depolarization on somatostatin gene expression in cultured fetal rat cerebrocortical cells.	Potassium	10-19	somatostatin	Rattus norvegicus	46-58
7907136-1	1994	The stimulatory effect of potassium depolarization upon somatostatin (SS) mRNA levels in primary cultures of fetal cerebrocortical cells was analyzed.	Potassium	26-35	somatostatin	Rattus norvegicus	56-68
7907136-6	1994	In contrast, Na+ channel blockade by TTX did not modify the 24 hr potassium-induced increase in SS mRNA, although it partially abolished potassium-induced SS secretion.	Potassium	137-146	somatostatin	Rattus norvegicus	155-157
7907136-1	1994	The stimulatory effect of potassium depolarization upon somatostatin (SS) mRNA levels in primary cultures of fetal cerebrocortical cells was analyzed.	Potassium	26-35	somatostatin	Rattus norvegicus	70-72
7907137-7	1994	Fifty percent (22 of 45) of pyramidal cells were hyperpolarized by [Met5]enkephalin; this resulted from an increase in potassium conductance, and it was mimicked by DPDPE and blocked by naltrindole.	Potassium	119-128	proenkephalin	Rattus norvegicus	73-83
7907136-4	1994	At this time, potassium (30 and 56 mM) acted as a secretagogue, stimulating SS secretion, but was also effective in stimulating SS mRNA levels, suggesting that SS secretion can be coupled to SS mRNA accumulation.	Potassium	14-23	somatostatin	Rattus norvegicus	76-78
7907136-4	1994	At this time, potassium (30 and 56 mM) acted as a secretagogue, stimulating SS secretion, but was also effective in stimulating SS mRNA levels, suggesting that SS secretion can be coupled to SS mRNA accumulation.	Potassium	14-23	somatostatin	Rattus norvegicus	128-130
7907136-4	1994	At this time, potassium (30 and 56 mM) acted as a secretagogue, stimulating SS secretion, but was also effective in stimulating SS mRNA levels, suggesting that SS secretion can be coupled to SS mRNA accumulation.	Potassium	14-23	somatostatin	Rattus norvegicus	128-130
7907136-4	1994	At this time, potassium (30 and 56 mM) acted as a secretagogue, stimulating SS secretion, but was also effective in stimulating SS mRNA levels, suggesting that SS secretion can be coupled to SS mRNA accumulation.	Potassium	14-23	somatostatin	Rattus norvegicus	128-130
8108449-4	1994	In addition, three K-ras alleles, designated as susceptible (Ks), intermediate (Ki), or resistant (Kr), were identified by sequence analysis of the second intron of the K-ras gene from 32 strains of mice.	Potassium	61-63	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	19-24
7908173-7	1994	Northern blot analysis demonstrated that renal alpha 2B-AR mRNA levels increased (190% of control) after 4 or 14 days on a potassium-deficient diet.	Potassium	123-132	adrenoceptor alpha 2B	Rattus norvegicus	47-58
8013552-3	1994	The potassium (K+)-evoked acetylcholine release from the splanchnic nerve terminals was inhibited by morphine (10 microM), a mu-opioid receptor agonist, and [D-Pen2,D-Pen5]enkephalin (DPDPE, 1 and 10 microM), a delta-opioid receptor agonist.	Potassium	4-13	proenkephalin	Rattus norvegicus	172-182
7507836-0	1994	Both low sodium and high potassium intake increase the level of adrenal angiotensin-II receptor type 1, but not that of adrenocorticotropin receptor.	Potassium	25-34	angiotensinogen	Rattus norvegicus	72-86
8141164-3	1994	In essential hypertensive subjects, intracellular potassium is decreased and intracellular sodium increased, which is consistent with insulin resistance.	Potassium	50-59	insulin	Homo sapiens	134-141
8086322-4	1994	Interest has been expressed on the influence of diuretic induced hypokalemia (and intracellular potassium deficiency) in inducing insulin resistance.	Potassium	96-105	insulin	Homo sapiens	130-137
7507836-8	1994	We have shown that a high potassium intake increased plasma aldosterone levels to 25.9 ng/dl and also led to 1.84- and 1.95-fold increases in the level of ZG AT1 receptor protein and AT1 receptor mRNA, whereas the ZG P450c18 mRNA level was increased 3.5-fold.	Potassium	26-35	angiotensin II receptor, type 1a	Rattus norvegicus	158-161
7507836-8	1994	We have shown that a high potassium intake increased plasma aldosterone levels to 25.9 ng/dl and also led to 1.84- and 1.95-fold increases in the level of ZG AT1 receptor protein and AT1 receptor mRNA, whereas the ZG P450c18 mRNA level was increased 3.5-fold.	Potassium	26-35	angiotensin II receptor, type 1a	Rattus norvegicus	183-186
22133110-1	1994	Abstract   In Table I of the paper Growth hormone responsive dermatosis in three dogs (New Zealand Veterinary Journal 41, 19.5-9, 1993), the units for the following biochemical tests are given in mumol/l, whereas the correct units are mmol/l: blood urea, glucose, cholesterol, calcium, inorganic phosphate, sodium and potassium.	Potassium	318-327	somatotropin	Canis lupus familiaris	35-49
7507836-11	1994	Collectively, these results indicate that the increased aldosterone secretion induced by low sodium or high potassium intake involves concomitant increases in AT1 receptor and P450c18 mRNAs, which are effectively translated into their respective proteins, and that the expression of both proteins is mediated in part by AII.	Potassium	108-117	angiotensin II receptor, type 1a	Rattus norvegicus	159-162
7507836-11	1994	Collectively, these results indicate that the increased aldosterone secretion induced by low sodium or high potassium intake involves concomitant increases in AT1 receptor and P450c18 mRNAs, which are effectively translated into their respective proteins, and that the expression of both proteins is mediated in part by AII.	Potassium	108-117	angiotensinogen	Rattus norvegicus	320-323
8191539-4	1994	The suppression of dehydrogenase activity allows glucocorticoids to activate the mineralocorticoid receptor, leading to classical mineralocorticoid type effects such as sodium retention and potassium excretion.	Potassium	190-199	nuclear receptor subfamily 3 group C member 2	Homo sapiens	81-107
7638042-3	1994	Of the greatest importance is the direct influence of Mg2+ on the cardiomyocyte which includes: reduction of cytoplasmatic calcium overload, protection of mitochondria against calcium influx, and diminution of cellular potassium, magnesium and ATP depletion.	Potassium	219-228	mucin 7, secreted	Homo sapiens	54-57
8290553-4	1994	In this study, we show that exposure of primary rat and human astrocytes to heat-activated HIV-1 virions, or to eukaryotically expressed HIV-1 and HIV-2 envelope glycoproteins (gp120) stimulates amiloride-sensitive Na+/H+ antiport, potassium conductance, and glutamate efflux.	Potassium	232-241	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	177-182
7911685-5	1994	The NMDA receptor antagonist CPP abolished the flurbiprofen-induced potentiation to both modes of stimulation, whilst the metabotropic glutamate receptor antagonist, L-AP3, blocked potassium-stimulated enhancement but had a variable effect on veratridine-stimulated release.	Potassium	181-190	leucine aminopeptidase 3	Rattus norvegicus	166-171
7942378-0	1994	Some effects of a low sodium diet high in potassium on the renin-angiotensin system and plasma electrolyte concentrations in normal dogs.	Potassium	42-51	renin	Canis lupus familiaris	59-64
7527103-8	1994	Trandolaprilat potentiated the endothelium-dependent hyperpolarizations evoked by a subthreshold concentration of bradykinin, and these endothelium-dependent hyperpolarizations were inhibited by high-potassium solution.	Potassium	200-209	kininogen 1	Canis lupus familiaris	114-124
8285977-3	1994	Increased serum glucose and insulin may also contribute to the intracellular shift of potassium after sympathomimetic use.	Potassium	86-95	insulin	Homo sapiens	28-35
8012686-2	1994	Ang(1-7) had three major effects producing, (1) a substantial natriuresis and diuresis, (2) an increase in urinary sodium concentration associated with a fall in potassium concentration and (3) an increase in glomerular filtration rate without affecting renal vascular resistance.	Potassium	162-171	angiogenin	Rattus norvegicus	0-7
7875033-7	1994	The reversal potential for the SS-28-induced hyperpolarization was -116 mV, which is approximately the potassium equilibrium potential.	Potassium	103-112	somatostatin	Rattus norvegicus	31-36
8070497-1	1994	The influence of angiotensin converting enzyme (ACE) inhibition on acute extrarenal and renal potassium elimination in stable chronic renal failure has been examined in 10 male patients median age 44 y; mean CLCR 42 ml.min-1.1.73 m-2.	Potassium	94-103	angiotensin I converting enzyme	Homo sapiens	48-51
7729694-5	1994	In agreement with other reports, lower Ks values for Adh correlate with a high level of gene expression and relatively high percentage of G+C content in the third codon position, while the opposite applies to Adh-dup.	Potassium	39-41	Alcohol dehydrogenase	Drosophila melanogaster	53-56
7700069-6	1994	The effects of angiotensin-converting enzyme inhibition on insulin sensitivity and glucose tolerance are reviewed in the context of the glucose-potassium cycle.	Potassium	144-153	insulin	Homo sapiens	59-66
7931240-2	1994	All the compounds tested interacted with cyt P-450 with Ks values ranging between 14 and 358 microM (clorgyline Ks = 10.5 microM).	Potassium	56-58	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	41-50
7908953-10	1994	In contrast, bath application of high potassium (7 mM) and bicuculline (10 microM) generated spontaneous and evoked epileptiform activity in both nonirradiated and irradiated CA3 regions.	Potassium	38-47	carbonic anhydrase 3	Rattus norvegicus	175-178
8263511-5	1994	Potassium-stimulated TRH release was significantly elevated over basal release 12, 24, and 48 h after ECS.	Potassium	0-9	thyrotropin releasing hormone	Rattus norvegicus	21-24
8263511-6	1994	Potassium-stimulated calcium-dependent TRH release increased linearly after ECS, reaching its highest level 48 h after seizure.	Potassium	0-9	thyrotropin releasing hormone	Rattus norvegicus	39-42
8263511-7	1994	Thus, although enhanced calcium-dependent TRH release was associated with elevated tissue levels, this relationship was not proportional in that tissue TRH was elevated to the same extent at all times after ECS, whereas potassium-evoked calcium-dependent TRH release increased gradually over time after seizure.	Potassium	220-229	thyrotropin releasing hormone	Rattus norvegicus	42-45
8014889-8	1994	Neurotensin also caused an inward current even in potassium-free internal and external solutions; this current was accompanied by a conductance increase, reversed close to 0 mV and was inhibited by reduction of the extracellular sodium concentration (from 150 to 20 mM).	Potassium	50-59	neurotensin	Rattus norvegicus	0-11
7507992-7	1994	These results are consistent with the hypothesis that the neuromodulatory action of ANF is mediated by the activation of potassium conductances.	Potassium	121-130	natriuretic peptides A	Oryctolagus cuniculus	84-87
7915002-5	1994	ANF produced a significantly greater suppression of potassium-induced aldosterone secretion in cells from OVX estradiol-treated rats than in cells from OVX progesterone-treated animals.	Potassium	52-61	natriuretic peptide A	Rattus norvegicus	0-3
8253841-5	1993	When coexpressed in Xenopus oocytes with a beta subunit isolated from the same cDNA library, the ATPase is able to transport rubidium (a potassium surrogate) inward, and hydrogen outward, leading to alkalization of the intracellular compartment and acidification of the external medium.	Potassium	137-146	dynein axonemal heavy chain 8	Homo sapiens	97-103
8145891-0	1994	Voltage-dependent potassium currents in ovine somatotrophs and their function in growth hormone secretion.	Potassium	18-27	somatotropin	Ovis aries	81-95
8145892-0	1994	Epidermal growth factor treatment induces D2 dopamine receptors functionally coupled to delayed outward potassium current (IK) in GH4C1 clonal anterior pituitary cells.	Potassium	104-113	epidermal growth factor like 1	Rattus norvegicus	0-23
7597651-6	1994	For example, since the wild-type KAT1 K+ channel reduces the potassium requirement of trk1 delta trk2 delta cells from approximately 50 mM to less than 50 microM, the function of mutant channels can be assessed over a 1,000-fold range in concentration of the permeant ion.	Potassium	61-70	histone acetyltransferase catalytic subunit HAT1	Saccharomyces cerevisiae S288C	33-37
7597651-6	1994	For example, since the wild-type KAT1 K+ channel reduces the potassium requirement of trk1 delta trk2 delta cells from approximately 50 mM to less than 50 microM, the function of mutant channels can be assessed over a 1,000-fold range in concentration of the permeant ion.	Potassium	61-70	Trk1p	Saccharomyces cerevisiae S288C	86-90
7597651-6	1994	For example, since the wild-type KAT1 K+ channel reduces the potassium requirement of trk1 delta trk2 delta cells from approximately 50 mM to less than 50 microM, the function of mutant channels can be assessed over a 1,000-fold range in concentration of the permeant ion.	Potassium	61-70	Trk2p	Saccharomyces cerevisiae S288C	97-101
8298079-1	1993	We present a biophysical model of a slowly inactivating potassium ion current IKS, based on recent voltage-clamp data from layer V pyramidal neurons in the cat sensorimotor cortex and show that the interplay between a persistent sodium current INaP and IKS is able to produce intrinsic membrane potential oscillations in the 10- to 50-frequency range.	Potassium	56-65	NFKB inhibitor zeta	Homo sapiens	244-248
8179835-3	1993	Also, the renin-aldosterone stimulation testing on this patient performed by sodium restricted diet and furosemide, upright position and by angiotensin converting enzyme inhibition (captopril, 50 mg) showed the blunted renin and aldosterone responses to each of these stimuli, almost no changes from baseline renin and aldosterone levels, it was concluded that the underlying defect responsible for hyperkalemia in this case was hyporeninemic hypoaldosteronism and this was aggravated by other factors or drugs affecting potassium homeostasis.	Potassium	521-530	renin	Homo sapiens	10-15
8179835-3	1993	Also, the renin-aldosterone stimulation testing on this patient performed by sodium restricted diet and furosemide, upright position and by angiotensin converting enzyme inhibition (captopril, 50 mg) showed the blunted renin and aldosterone responses to each of these stimuli, almost no changes from baseline renin and aldosterone levels, it was concluded that the underlying defect responsible for hyperkalemia in this case was hyporeninemic hypoaldosteronism and this was aggravated by other factors or drugs affecting potassium homeostasis.	Potassium	521-530	renin	Homo sapiens	219-224
8179835-3	1993	Also, the renin-aldosterone stimulation testing on this patient performed by sodium restricted diet and furosemide, upright position and by angiotensin converting enzyme inhibition (captopril, 50 mg) showed the blunted renin and aldosterone responses to each of these stimuli, almost no changes from baseline renin and aldosterone levels, it was concluded that the underlying defect responsible for hyperkalemia in this case was hyporeninemic hypoaldosteronism and this was aggravated by other factors or drugs affecting potassium homeostasis.	Potassium	521-530	renin	Homo sapiens	219-224
8145166-0	1993	Potassium currents operated by thyrotrophin-releasing hormone in dissociated CA1 pyramidal neurones of rat hippocampus.	Potassium	0-9	thyrotropin releasing hormone	Rattus norvegicus	31-61
7509860-7	1993	CCKA receptor-related inhibition was generated by a potassium current that reversed at a reversal potential E(rev) of -73 +/- 1 (mean +/- SE) mV with bathing potassium concentration [K+]o = 6 mM and at -88 +/- 1 with [K+]o = 3 mM, in agreement with the Nernst equation for potassium ions.	Potassium	52-61	cholecystokinin A receptor	Rattus norvegicus	0-13
7509860-7	1993	CCKA receptor-related inhibition was generated by a potassium current that reversed at a reversal potential E(rev) of -73 +/- 1 (mean +/- SE) mV with bathing potassium concentration [K+]o = 6 mM and at -88 +/- 1 with [K+]o = 3 mM, in agreement with the Nernst equation for potassium ions.	Potassium	158-167	cholecystokinin A receptor	Rattus norvegicus	0-13
7509860-7	1993	CCKA receptor-related inhibition was generated by a potassium current that reversed at a reversal potential E(rev) of -73 +/- 1 (mean +/- SE) mV with bathing potassium concentration [K+]o = 6 mM and at -88 +/- 1 with [K+]o = 3 mM, in agreement with the Nernst equation for potassium ions.	Potassium	158-167	cholecystokinin A receptor	Rattus norvegicus	0-13
7509860-12	1993	CCKB receptor-related excitation, in the neurons (30% of cases) in which clear response reversal was observed, appeared to be generated by a decrease of a potassium conductance.	Potassium	155-164	cholecystokinin B receptor	Rattus norvegicus	0-13
8145166-0	1993	Potassium currents operated by thyrotrophin-releasing hormone in dissociated CA1 pyramidal neurones of rat hippocampus.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	77-80
8274279-5	1993	Inhibition of RNA or protein synthesis, or treatment with potassium, all of which prevent PCD after nerve growth factor deprivation, prevented LIF-induced death.	Potassium	58-67	nerve growth factor	Homo sapiens	100-119
8274438-6	1993	In vivo zona glomerulosa expression of CYP11B1 was enhanced by ACTH treatment or potassium depletion and was lowered by potassium repletion.	Potassium	81-90	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	39-46
8274438-6	1993	In vivo zona glomerulosa expression of CYP11B1 was enhanced by ACTH treatment or potassium depletion and was lowered by potassium repletion.	Potassium	120-129	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	39-46
8274438-7	1993	CYP11B2 expression disappeared upon potassium depletion or ACTH treatment, but reappeared during potassium repletion.	Potassium	36-45	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	0-7
8274438-7	1993	CYP11B2 expression disappeared upon potassium depletion or ACTH treatment, but reappeared during potassium repletion.	Potassium	97-106	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	0-7
8274438-8	1993	In vitro, only CYP11B1 activity was detectable and responsive to ACTH treatment in zona glomerulosa cells cultured at a potassium concentration of 6.4 mmol/l.	Potassium	120-129	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	15-22
8274438-9	1993	Aldosterone biosynthetic activity and mRNA encoding CYP11B2 could be detected only after at least 1 day of exposure to a high extracellular potassium concentration (> or = 12 mmol/l).	Potassium	140-149	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	52-59
7903859-0	1993	Myosin light chain kinase occurs in bullfrog sympathetic neurons and may modulate voltage-dependent potassium currents.	Potassium	100-109	myosin light chain kinase	Gallus gallus	0-25
8274279-5	1993	Inhibition of RNA or protein synthesis, or treatment with potassium, all of which prevent PCD after nerve growth factor deprivation, prevented LIF-induced death.	Potassium	58-67	LIF interleukin 6 family cytokine	Homo sapiens	143-146
8215747-10	1993	The beneficial effects of ACE inhibition may be due to both hemodynamic (eg, reduction in glomerular capillary and intraglomerular pressures) and nonhemodynamic (eg, potassium-sparing and reduction in mesangial proliferation) mechanisms.	Potassium	166-175	angiotensin I converting enzyme	Homo sapiens	26-29
8248201-0	1993	Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.	Potassium	60-69	insulin like growth factor 1	Homo sapiens	94-122
8306432-0	1993	Potassium-induced changes in excitability in the hippocampal CA1 region of immature and adult rats.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	61-64
8306434-7	1993	The pattern of c-fos expression in adult animals after mechanical damage was compared with other models of focal brain injury: application of potassium to the cortical surface and devascularization.	Potassium	142-151	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	15-20
8306434-8	1993	Though all models generated c-fos expression far from the lesion site, potassium application resulted in higher numbers of c-fos-positive cells, particularly in the cingulate cortex.	Potassium	71-80	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	123-128
8291761-5	1993	Concentrations of total protein, albumin, and IgG were greater, and concentrations of glucose and potassium were lower in CSF obtained from the lumbar rather than the cisternal site.	Potassium	98-107	colony stimulating factor 2	Homo sapiens	122-125
8187634-7	1993	At no stage during the early development of trigeminal neurons do depolarising levels of potassium ions affect the expression of either p75 mRNA or trkA mRNA.	Potassium	89-98	PC4 and SFRS1 interacting protein 1	Homo sapiens	136-139
8287405-2	1993	The aim of the study was to determine whether age related changes in L-type calcium current (ICa), transient outward potassium current (ITO), and inwardly rectifying potassium current (IK1) are involved in the prolongation of the early (ICa, ITO) and late (IK1) portions of the rat action potential plateau.	Potassium	166-175	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	185-188
8275698-0	1993	Effect of potassium deficiency and gossypol on urinary N-acetyl-beta-glucosaminidase excretion in the rat.	Potassium	10-19	O-GlcNAcase	Rattus norvegicus	55-84
8275698-4	1993	The low potassium diet produced high NAG levels rather than the gossypol.	Potassium	8-17	O-GlcNAcase	Rattus norvegicus	37-40
8187634-7	1993	At no stage during the early development of trigeminal neurons do depolarising levels of potassium ions affect the expression of either p75 mRNA or trkA mRNA.	Potassium	89-98	neurotrophic receptor tyrosine kinase 1	Homo sapiens	148-152
8229210-5	1993	Here, we report the functional properties and developmental localization of a second Xenopus Shaker-like gene (Xenopus Kv 1.1; XSha1; GenBank accession number M94258) encoding a potassium current.	Potassium	178-187	potassium channel, voltage gated shaker related subfamily A, member 1 S homeolog	Xenopus laevis	127-132
8236352-3	1993	METHODS: Rat interleukin-1 beta cDNA, synthesized from stimulated rat peritoneal macrophage RNA by reverse transcription and polymerase chain reaction and cloned in plasmid Bluescript KS+, was used to evaluate the expression of interleukin-1 beta mRNA in cerebral cortex from spontaneously hypertensive rats and normotensive rats subjected to permanent middle cerebral artery occlusion.	Potassium	184-187	interleukin 1 beta	Rattus norvegicus	13-31
8117514-10	1993	Factors that may contribute to the reduction in VA by ACE inhibitors include: increase in serum potassium; unloading of the ventricle; decrease in myocardial oxygen consumption.	Potassium	96-105	angiotensin I converting enzyme	Homo sapiens	54-57
7505348-0	1993	Renal vascular induction of TGF-beta 2 and renin by potassium depletion.	Potassium	52-61	transforming growth factor, beta receptor 2	Rattus norvegicus	28-38
7505348-0	1993	Renal vascular induction of TGF-beta 2 and renin by potassium depletion.	Potassium	52-61	renin	Rattus norvegicus	43-48
7505348-6	1993	Potassium depletion induced both TGF-beta 2 and renin immunoreactivity in renal arterioles and the JGA but had no effect on TGF-beta 1 and TGF-beta 3 isoforms.	Potassium	0-9	transforming growth factor, beta receptor 2	Rattus norvegicus	33-43
7505348-6	1993	Potassium depletion induced both TGF-beta 2 and renin immunoreactivity in renal arterioles and the JGA but had no effect on TGF-beta 1 and TGF-beta 3 isoforms.	Potassium	0-9	renin	Rattus norvegicus	48-53
8198803-7	1993	Therefore, in potassium depletion the decreased synthesis of cortical and medullary prostanoids, in the face of the increased generation of AT II, contributed to reducing the glomerular filtration rate and facilitate the expression of vasopressin action.	Potassium	14-23	angiotensinogen	Homo sapiens	140-145
8238396-1	1993	Whole cell and single-channel inwardly rectifying potassium currents (IK1) of freshly isolated single fetal (12 and 18 days) and neonatal (1, 5, and 10 days) rat ventricular myocytes were recorded using patch-clamp techniques.	Potassium	50-59	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	70-73
8198803-7	1993	Therefore, in potassium depletion the decreased synthesis of cortical and medullary prostanoids, in the face of the increased generation of AT II, contributed to reducing the glomerular filtration rate and facilitate the expression of vasopressin action.	Potassium	14-23	arginine vasopressin	Homo sapiens	235-246
8270912-1	1993	M-1 cells, derived from a microdissected cortical collecting duct of a transgenic mouse, grown to confluence on a permeable support, develop a lumen-negative amiloride-sensitive transepithelial potential, reabsorb sodium, and secrete potassium.	Potassium	234-243	cholinergic receptor, muscarinic 1, CNS	Mus musculus	0-3
7904926-2	1993	Atrial natriuretic factor effects on neuronal noradrenaline release evoked by angiotensin II or III and high potassium solution plus angiotensin II and III in the rat hypothalamus were studied.	Potassium	109-118	natriuretic peptide A	Rattus norvegicus	0-25
8408463-0	1993	Effects of acute mineralocorticoid and glucocorticoid receptor blockade on the excretion of an acute potassium load in healthy humans.	Potassium	101-110	nuclear receptor subfamily 3 group C member 1	Homo sapiens	39-62
7905923-16	1993	The somatostatin-induced desensitization was of the homologous type; no cross-desensitization to opiate or alpha 2-adrenoceptor agonists (which activate the same potassium conductance) occurred.	Potassium	162-171	somatostatin	Cavia porcellus	4-16
8378352-5	1993	Whereas the KS cells express wild-type p53, the protein is undetectable in the parental K562 cells.	Potassium	12-14	tumor protein p53	Homo sapiens	39-42
7692301-1	1993	The Drosophila ether-a-go-go (eag) mutant is responsible for altered potassium currents in excitable tissue.	Potassium	69-78	ether a go-go	Drosophila melanogaster	15-28
7692301-1	1993	The Drosophila ether-a-go-go (eag) mutant is responsible for altered potassium currents in excitable tissue.	Potassium	69-78	ether a go-go	Drosophila melanogaster	30-33
8239277-3	1993	When incorporated into this bilayer, the A beta P forms cation selective channels capable of transporting calcium and some monovalent cations including cesium, lithium, potassium, and sodium.	Potassium	169-178	amyloid beta precursor protein	Homo sapiens	41-47
8214016-0	1993	Angiotensin II type 2 receptor-modulated changes in potassium currents in cultured neurons.	Potassium	52-61	angiotensin II receptor, type 2	Rattus norvegicus	0-30
8242372-3	1993	Exogenous CGA (purified from human adrenals) when applied to perfused rat retina potently inhibited the potassium-induced release of endogenous dopamine (DA).	Potassium	104-113	chromogranin A	Homo sapiens	10-13
8403806-11	1993	In addition, whereas the glycaemic profile was superimposable, the response of the plasma insulin concentration was significantly greater with than without maintenance of the plasma potassium concentration (total area 79 +/- 14 versus 63 +/- 8 nmol l-1 3 h, P < 0.04).	Potassium	182-191	insulin	Homo sapiens	90-97
8403806-13	1993	We conclude that (a) insulin causes antinatriuresis, antikaliuresis and hypokalaemia under physiological conditions; (b) in hyperinsulinaemic (insulin-resistant) patients with essential hypertension, the antinatriuretic action of insulin is quantitatively preserved; and (c) clamping plasma potassium levels prevents insulin-induced antikaliuresis but not antinatriuresis, and potentiates the insulin secretory response to glucose.	Potassium	291-300	insulin	Homo sapiens	21-28
8242056-0	1993	A novel SCN4A mutation causing myotonia aggravated by cold and potassium.	Potassium	63-72	sodium voltage-gated channel alpha subunit 4	Homo sapiens	8-13
8373370-5	1993	In addition, the values of Km for thrombin-fibrinogen reaction were measured at different solution viscosities in order to derive the equilibrium dissociation constant, Ks, of this interaction.	Potassium	169-171	coagulation factor II, thrombin	Homo sapiens	34-42
8373370-5	1993	In addition, the values of Km for thrombin-fibrinogen reaction were measured at different solution viscosities in order to derive the equilibrium dissociation constant, Ks, of this interaction.	Potassium	169-171	fibrinogen beta chain	Homo sapiens	43-53
8373370-6	1993	These experiments showed that the Ks values for thrombin-fibrinogen binding was equal to 1.8 microM at 25 degrees C. Altogether these results indicated that fibrinogen, though interacting with both the catalytic pocket and the fibrinogen recognition site on the thrombin molecule, dissociates from Michaelis complex with a rate comparable with that shown by amide substrates, which interact only with the catalytic site.	Potassium	34-36	coagulation factor II, thrombin	Homo sapiens	48-56
8373370-6	1993	These experiments showed that the Ks values for thrombin-fibrinogen binding was equal to 1.8 microM at 25 degrees C. Altogether these results indicated that fibrinogen, though interacting with both the catalytic pocket and the fibrinogen recognition site on the thrombin molecule, dissociates from Michaelis complex with a rate comparable with that shown by amide substrates, which interact only with the catalytic site.	Potassium	34-36	fibrinogen beta chain	Homo sapiens	57-67
8373370-6	1993	These experiments showed that the Ks values for thrombin-fibrinogen binding was equal to 1.8 microM at 25 degrees C. Altogether these results indicated that fibrinogen, though interacting with both the catalytic pocket and the fibrinogen recognition site on the thrombin molecule, dissociates from Michaelis complex with a rate comparable with that shown by amide substrates, which interact only with the catalytic site.	Potassium	34-36	fibrinogen beta chain	Homo sapiens	157-167
8373370-6	1993	These experiments showed that the Ks values for thrombin-fibrinogen binding was equal to 1.8 microM at 25 degrees C. Altogether these results indicated that fibrinogen, though interacting with both the catalytic pocket and the fibrinogen recognition site on the thrombin molecule, dissociates from Michaelis complex with a rate comparable with that shown by amide substrates, which interact only with the catalytic site.	Potassium	34-36	fibrinogen beta chain	Homo sapiens	157-167
8373370-6	1993	These experiments showed that the Ks values for thrombin-fibrinogen binding was equal to 1.8 microM at 25 degrees C. Altogether these results indicated that fibrinogen, though interacting with both the catalytic pocket and the fibrinogen recognition site on the thrombin molecule, dissociates from Michaelis complex with a rate comparable with that shown by amide substrates, which interact only with the catalytic site.	Potassium	34-36	coagulation factor II, thrombin	Homo sapiens	262-270
18613081-3	1993	The extraction of lysozyme was affected by the concentration of potassium or barium but was almost independent of that of sodium or calcium, whose ionic diameter is smaller than that of potassium and barium.	Potassium	64-73	lysozyme	Homo sapiens	18-26
7690067-3	1993	Elevating extracellular potassium concentration (50 mM, 1 min) evoked the calcium-dependent release of both ASP (approximately 50% increase) and GLU (approximately 200% increase) from hippocampal slices and from minislices of area CA1.	Potassium	24-33	carbonic anhydrase 1	Rattus norvegicus	231-234
7692419-6	1993	The sequence of changes suggests that the decrease of potassium and magnesium after ventricular tachycardia was due to a shift of the electrolytes into cells, related to the insulin-mediated movement of glucose from the blood into cells.	Potassium	54-63	insulin	Homo sapiens	174-181
8102879-0	1993	Hydrolysis of adenosine 5"-triphosphate by Escherichia coli GroEL: effects of GroES and potassium ion.	Potassium	88-97	GroEL	Escherichia coli	60-65
8102879-1	1993	The potassium-ion activation constant (Kact) for the ATPase activity of Escherichia coli chaperonin groEL is inversely dependent upon the ATP concentration over at least 3 orders of magnitude.	Potassium	4-13	ATPase	Escherichia coli	53-59
8102879-1	1993	The potassium-ion activation constant (Kact) for the ATPase activity of Escherichia coli chaperonin groEL is inversely dependent upon the ATP concentration over at least 3 orders of magnitude.	Potassium	4-13	chaperonin GroEL	Escherichia coli	89-105
18613081-3	1993	The extraction of lysozyme was affected by the concentration of potassium or barium but was almost independent of that of sodium or calcium, whose ionic diameter is smaller than that of potassium and barium.	Potassium	186-195	lysozyme	Homo sapiens	18-26
8340152-3	1993	The present study uses 769 individuals in 58 Utah pedigrees to analyze the association of urinary potassium with urinary kallikrein within statistically inferred kallikrein genotypes.	Potassium	98-107	kallikrein related peptidase 4	Homo sapiens	121-131
8340152-3	1993	The present study uses 769 individuals in 58 Utah pedigrees to analyze the association of urinary potassium with urinary kallikrein within statistically inferred kallikrein genotypes.	Potassium	98-107	kallikrein related peptidase 4	Homo sapiens	162-172
8340152-4	1993	Fitting genotype-specific curves relating urinary kallikrein level to 12-hour urinary potassium amount within a major gene, polygene, and common environment model, we showed a significant statistical urinary potassium interaction with the inferred major gene for kallikrein (P = .0002).	Potassium	86-95	kallikrein related peptidase 4	Homo sapiens	50-60
8340152-4	1993	Fitting genotype-specific curves relating urinary kallikrein level to 12-hour urinary potassium amount within a major gene, polygene, and common environment model, we showed a significant statistical urinary potassium interaction with the inferred major gene for kallikrein (P = .0002).	Potassium	208-217	kallikrein related peptidase 4	Homo sapiens	50-60
8340152-4	1993	Fitting genotype-specific curves relating urinary kallikrein level to 12-hour urinary potassium amount within a major gene, polygene, and common environment model, we showed a significant statistical urinary potassium interaction with the inferred major gene for kallikrein (P = .0002).	Potassium	208-217	kallikrein related peptidase 4	Homo sapiens	263-273
8340152-5	1993	The heterozygotes (with a frequency of 50%) had a significant association between urinary kallikrein and potassium (slope, 0.51 +/- 0.04 SD), whereas there was no association with potassium in the low homozygotes, suggesting a genetic defect involving the kallikrein response to potassium.	Potassium	105-114	kallikrein related peptidase 4	Homo sapiens	90-100
8340152-6	1993	The model predicted that an increase in urinary potassium excretion of 0.8 SD above the mean in these pedigrees would be associated with high kallikrein levels in the heterozygotes similar to the high homozygotes.	Potassium	48-57	kallikrein related peptidase 4	Homo sapiens	142-152
8340152-7	1993	A decrease of 1.3 SD in urinary potassium excretion in heterozygous individuals was associated with kallikrein levels similar to the homozygous individuals with low kallikrein.	Potassium	32-41	kallikrein related peptidase 4	Homo sapiens	100-110
8295075-0	1993	Differential modulation of potassium currents by cAMP and its long-term and short-term effects: dunce and rutabaga mutants of Drosophila.	Potassium	27-36	dunce	Drosophila melanogaster	96-101
8413845-5	1993	Prazosin decreased both the basal and potassium-evoked release of NPY.	Potassium	38-47	neuropeptide Y	Rattus norvegicus	66-69
8413845-6	1993	Propranolol had the most profound effect on release of NPY, causing a significant decrease in basal release and a large decrease in the potassium-evoked release of NPY from slices of hypothalamus.	Potassium	136-145	neuropeptide Y	Rattus norvegicus	55-58
8413932-9	1993	Raising the concentration of potassium (60 mM) in the perfusate increased corticotropin-releasing factor levels to 2.04 +/- 0.37 fmol/50 microliters.	Potassium	29-38	corticotropin releasing hormone	Rattus norvegicus	74-104
8413845-6	1993	Propranolol had the most profound effect on release of NPY, causing a significant decrease in basal release and a large decrease in the potassium-evoked release of NPY from slices of hypothalamus.	Potassium	136-145	neuropeptide Y	Rattus norvegicus	164-167
8413932-15	1993	Basal and potassium-evoked levels of corticotropin-releasing factor were measured in dialysate collected from the amygdala (1.20 +/- 0.22 and 2.05 +/- 0.48 fmol/50 microliters, respectively) and frontal cortex (0.51 +/- 0.10 and 1.64 +/- 0.15 fmol/50 microliters, respectively).	Potassium	10-19	corticotropin releasing hormone	Rattus norvegicus	37-67
8296215-4	1993	The results were as follows: The hHSS does exist in the human fetal liver, hHSS could increase the viability of intoxicated hepatocytes, maintain the intracellular calcium homeostasis, and decrease the leakage of intracellular potassium and ALT into the culture medium.	Potassium	227-236	growth factor, augmenter of liver regeneration	Homo sapiens	33-37
8296215-4	1993	The results were as follows: The hHSS does exist in the human fetal liver, hHSS could increase the viability of intoxicated hepatocytes, maintain the intracellular calcium homeostasis, and decrease the leakage of intracellular potassium and ALT into the culture medium.	Potassium	227-236	growth factor, augmenter of liver regeneration	Homo sapiens	75-79
8296215-5	1993	These results indicate that hHSS could protect hepatocytes against CCl4 through maintaining calcium homeostasis, preventing potassium leakage and sustaining stability of hepatocyte polasmalemma.	Potassium	124-133	growth factor, augmenter of liver regeneration	Homo sapiens	28-32
8358568-6	1993	However, large outward voltage-activated potassium currents were always observed in those cells which had been transfected with the vector containing the DNA encoding for MK-1.	Potassium	41-50	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	171-175
8393035-3	1993	A total of 40 to 70 mV of the membrane potential of peripheral T cells is produced by the direct electrogenic action of the asymmetric Na+K+ ATPase pump because the cells are depolarized by ouabain, an inhibitor of the pump, removal of extracellular potassium or reduction of temperature.	Potassium	250-259	dynein, axonemal, heavy chain 8	Mus musculus	141-147
8354016-6	1993	When ACE inhibitors are given hyperkalaemia may occur in patients with renal insufficiency, those taking potassium supplements or potassium-sparing diuretics, and in diabetic patients with mild renal impairment.	Potassium	105-114	angiotensin I converting enzyme	Homo sapiens	5-8
8354016-6	1993	When ACE inhibitors are given hyperkalaemia may occur in patients with renal insufficiency, those taking potassium supplements or potassium-sparing diuretics, and in diabetic patients with mild renal impairment.	Potassium	130-139	angiotensin I converting enzyme	Homo sapiens	5-8
8281293-0	1993	High external potassium induces an increase in the phosphorylation of the cytoskeletal protein MAP2 in rat hippocampal slices.	Potassium	14-23	microtubule-associated protein 2	Rattus norvegicus	95-99
8315226-11	1993	The greater rate of increase in potassium in healthy and athletic subjects supports the hypothesis of an age-related impairment of the beta 2-adrenergic process that mediates potassium flux into skeletal muscle.	Potassium	32-41	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-141
8315226-11	1993	The greater rate of increase in potassium in healthy and athletic subjects supports the hypothesis of an age-related impairment of the beta 2-adrenergic process that mediates potassium flux into skeletal muscle.	Potassium	175-184	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-141
8105061-3	1993	When applied to cells isolated from the rat anococcygeus, the extract reduced the inactivating voltage-dependent potassium current in a concentration-related manner, with an IC50 value (the concentration that reduced the current by 50%) of 56 micrograms mL-1.	Potassium	113-122	L1 cell adhesion molecule	Mus musculus	254-258
8377937-4	1993	An enhancement of acetylcholinesterase activity was also observed by stimulations with potassium injections through a canal of the probe.	Potassium	87-96	acetylcholinesterase	Rattus norvegicus	18-38
8517868-5	1993	Potassium-induced release of cholecystokinin from minislices of dorsal and ventral regions of the bed nucleus of stria terminalis was measured successfully using the above procedure to concentrate the peptide.	Potassium	0-9	cholecystokinin	Rattus norvegicus	29-44
8234011-1	1993	Intact calcitonin gene-related peptide (CGRP) receptors were solubilized from porcine neural membranes using sodium cholate: potassium buffer.	Potassium	125-134	calcitonin related polypeptide alpha	Homo sapiens	40-44
8333529-7	1993	These results indicate that in STC-1 cells a potassium current is increased by agents that stimulate CCK secretion, presumably by increasing the level of cytosolic calcium.	Potassium	45-54	cholecystokinin	Homo sapiens	101-104
8328315-5	1993	Clamping pHi to known values with 10 microM nigericin, a potassium proton ionophore, also influenced Cai: acid pHi lowered Cai, whereas alkaline pHi increased it.	Potassium	57-66	glucose-6-phosphate isomerase 1	Mus musculus	9-12
8389287-0	1993	Modulation of aldosterone synthase messenger ribonucleic acid levels by dietary sodium and potassium and by adrenocorticotropin.	Potassium	91-100	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	14-34
8330198-1	1993	In this study we examined long-lasting effects mediated by intracellular mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) on two voltage dependent potassium conductances in CA1 pyramidal neurons, i.e. the transient current IA and the delayed rectifier, and on the inward rectifier IQ, a mixed sodium/potassium current.	Potassium	167-176	carbonic anhydrase 1	Rattus norvegicus	193-196
8098726-11	1993	In a CM-containing OM in the absence of detectable IL-6, a neutralizing antibody to OM completely abrogated KS cell growth activity.	Potassium	108-110	oncostatin M	Homo sapiens	84-86
8330198-1	1993	In this study we examined long-lasting effects mediated by intracellular mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) on two voltage dependent potassium conductances in CA1 pyramidal neurons, i.e. the transient current IA and the delayed rectifier, and on the inward rectifier IQ, a mixed sodium/potassium current.	Potassium	320-329	carbonic anhydrase 1	Rattus norvegicus	193-196
8103200-0	1993	CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.	Potassium	80-89	carbonic anhydrase 3	Cavia porcellus	113-116
8498392-2	1993	Insulin is known to stimulate this disposal by enhancing potassium uptake into the cells.	Potassium	57-66	insulin	Homo sapiens	0-7
8498392-3	1993	Since dietary potassium is generally ingested in combination with carbohydrates, the predictable stimulation of endogenous insulin release may blunt the expected increase in plasma potassium.	Potassium	14-23	insulin	Homo sapiens	123-130
8498392-3	1993	Since dietary potassium is generally ingested in combination with carbohydrates, the predictable stimulation of endogenous insulin release may blunt the expected increase in plasma potassium.	Potassium	181-190	insulin	Homo sapiens	123-130
8498392-8	1993	On a separate study day, the subjects underwent the identical protocol, with the addition of 50 g of oral glucose to the potassium load to stimulate endogenous insulin release.	Potassium	121-130	insulin	Homo sapiens	160-167
8498392-16	1993	CONCLUSIONS: Exogenous glucose, by stimulating endogenous secretion of insulin, enhances extrarenal disposal of a potassium load.	Potassium	114-123	insulin	Homo sapiens	71-78
8327072-10	1993	The potassium perfusion produced an increase in the release of neuropeptide Y (peak at 71.4 +/- 7.1 pg/tube; p < 0.01), and this phenomenon was reproduced with the second potassium stimulation (peak at 47.7 +/- 2.3 vs pg/tube; p < 0.05).	Potassium	4-13	neuropeptide Y	Rattus norvegicus	63-77
8327072-10	1993	The potassium perfusion produced an increase in the release of neuropeptide Y (peak at 71.4 +/- 7.1 pg/tube; p < 0.01), and this phenomenon was reproduced with the second potassium stimulation (peak at 47.7 +/- 2.3 vs pg/tube; p < 0.05).	Potassium	174-183	neuropeptide Y	Rattus norvegicus	63-77
8513132-4	1993	Up-regulation of BDNF mRNA triggered by depolarization with high potassium, or exposure to the glutamate receptor agonist kainic acid, resulted both from higher levels of expression in neurones and from new recruitment of cells.	Potassium	65-74	brain-derived neurotrophic factor	Rattus norvegicus	17-21
8488854-12	1993	In the responders, fasting potassium levels at baseline were directly related to the decrease in BP (p < 0.01) and to the improvement of glucose-induced insulin response (p < 0.04) achieved after treatment.	Potassium	27-36	insulin	Homo sapiens	156-163
8413825-3	1993	Free met-enkephalin was secreted from the cultures in significant quantities in response to nonspecific depolarisation with 56 mM potassium, by a mechanism dependent upon extracellular calcium.	Potassium	130-139	proenkephalin	Rattus norvegicus	9-19
8488854-13	1993	Thus, the therapeutic effect of ACE inhibition is in part related to fractional potassium excretion, which, in turn, affects glucose tolerance through the influence of potassium levels on glucose-induced insulin release.	Potassium	80-89	angiotensin I converting enzyme	Homo sapiens	32-35
8488854-13	1993	Thus, the therapeutic effect of ACE inhibition is in part related to fractional potassium excretion, which, in turn, affects glucose tolerance through the influence of potassium levels on glucose-induced insulin release.	Potassium	80-89	insulin	Homo sapiens	204-211
8488854-13	1993	Thus, the therapeutic effect of ACE inhibition is in part related to fractional potassium excretion, which, in turn, affects glucose tolerance through the influence of potassium levels on glucose-induced insulin release.	Potassium	168-177	angiotensin I converting enzyme	Homo sapiens	32-35
8488854-13	1993	Thus, the therapeutic effect of ACE inhibition is in part related to fractional potassium excretion, which, in turn, affects glucose tolerance through the influence of potassium levels on glucose-induced insulin release.	Potassium	168-177	insulin	Homo sapiens	204-211
8466068-0	1993	Insulin decreases the serum potassium concentration during the anhepatic stage of liver transplantation.	Potassium	28-37	insulin	Homo sapiens	0-7
8466068-2	1993	The effectiveness of insulin in decreasing serum potassium concentration during the anhepatic stage of orthotopic liver transplantation was investigated.	Potassium	49-58	insulin	Homo sapiens	21-28
8466068-9	1993	CONCLUSIONS: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration, even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in the insulin-stimulated uptake of potassium.	Potassium	124-133	insulin	Homo sapiens	92-99
8466068-9	1993	CONCLUSIONS: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration, even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in the insulin-stimulated uptake of potassium.	Potassium	124-133	insulin	Homo sapiens	251-258
8466068-9	1993	CONCLUSIONS: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration, even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in the insulin-stimulated uptake of potassium.	Potassium	280-289	insulin	Homo sapiens	92-99
8466068-9	1993	CONCLUSIONS: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration, even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in the insulin-stimulated uptake of potassium.	Potassium	280-289	insulin	Homo sapiens	251-258
8390513-4	1993	More sodium, potassium and aldosterone were excreted during the daytime, but the natriuretic substance kallikrein was excreted at a fixed rate throughout the 24 h. During waking hours there was poor correlation between blood pressure and urinary sodium and potassium excretion.	Potassium	257-266	kallikrein related peptidase 4	Homo sapiens	103-113
8390513-5	1993	By contrast, at night when the aldosterone: kallikrein ratio fell, the sodium and potassium excretion rates were positively correlated with blood pressure.	Potassium	82-91	kallikrein related peptidase 4	Homo sapiens	44-54
8492147-0	1993	Serotonin-operated potassium current in CA1 neurons dissociated from rat hippocampus.	Potassium	19-28	carbonic anhydrase 1	Rattus norvegicus	40-43
8481339-6	1993	While the stimulatory effect of AII is potentiated by serotonin or increases in extracellular potassium, it is inhibited by dopamine, somatostatin and atrial natriuretic peptide.	Potassium	94-103	angiotensinogen	Rattus norvegicus	32-35
8458414-0	1993	External pH regulates the slowly activating potassium current IsK expressed in Xenopus oocytes.	Potassium	44-53	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	62-65
8466710-5	1993	Urinary sodium and potassium excretion differences were significantly related to kallikrein differences, with urinary potassium having the strongest relationship (r = 0.46, P = .0001).	Potassium	19-28	kallikrein related peptidase 4	Homo sapiens	81-91
8499606-2	1993	In the present study we demonstrate that both ET-1 (Emax: 238 +/- 29% of potassium contraction) and ET-2 (Emax: 231 +/- 36%) produce strong concentration-dependent contractions of circular segments of guinea-pig middle cerebral artery, whereas ET-3 has only weak effects (Emax: 32 +/- 13%).	Potassium	73-82	endothelin-1	Cavia porcellus	46-50
8466710-9	1993	Therefore, urinary potassium and pH probably represent the more acute effects of recent dietary sodium and potassium intake on urinary kallikrein levels.	Potassium	19-28	kallikrein related peptidase 4	Homo sapiens	135-145
8466710-9	1993	Therefore, urinary potassium and pH probably represent the more acute effects of recent dietary sodium and potassium intake on urinary kallikrein levels.	Potassium	107-116	kallikrein related peptidase 4	Homo sapiens	135-145
8466710-10	1993	Urinary potassium, pH, and systolic blood pressure differences explained 34% of the difference in kallikrein levels between monozygous twins.	Potassium	8-17	kallikrein related peptidase 4	Homo sapiens	98-108
8402382-9	1993	Furthermore, atrial natriuretic factor (10 nM) also reduced high potassium solution evoked secretion of norepinephrine.	Potassium	65-74	natriuretic peptide A	Rattus norvegicus	13-38
8440178-10	1993	TGF beta 1 inhibited the AII- and potassium-induced synthesis of aldosterone.	Potassium	34-43	transforming growth factor beta 1	Bos taurus	0-10
8458322-6	1993	Under the in vitro conditions used, this in vitro inhibitory effect of H-NS was affected by changes in the superhelical density of template DNAs and more significantly by the concentration of potassium (K+) ions.	Potassium	192-201	H-NS	Escherichia coli	71-75
8449988-3	1993	Potassium-depleted cells attached and spread on fibronectin-coated substrata over the same time course (15 min-2 h) as control cells.	Potassium	0-9	fibronectin 1	Homo sapiens	48-59
8459099-1	1993	The mechanisms underlying two potassium conductances which are activated by Ca2+ influx during the action potential in sympathetic prevertebral neurones of guinea pigs have been investigated pharmacologically.	Potassium	30-39	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	76-79
8440178-11	1993	These observations show that TGF beta 1 inhibits AII- and potassium-induced aldosterone synthesis and the early pathway of aldosterone biosynthesis by interfering with the transport of cholesterol across the mitochondrial membrane as well as inhibiting the late pathway of aldosterone biosynthesis.	Potassium	58-67	transforming growth factor beta 1	Bos taurus	29-39
8483162-7	1993	Comparison of the rates of silent (Ks) and nonsilent (Ka) substitutions of the rp49 gene and other genes completely sequenced in D. pseudoobscura and D. melanogaster confirms previous results indicating that rp49 is evolving slowly both at silent and nonsilent sites.	Potassium	35-37	Ribosomal protein L32	Drosophila melanogaster	79-83
8477053-4	1993	Application of exogenous IL-2 to hypothalamic slices produced significant decreases of potassium (25 mM)-evoked [3H]noradrenaline release (24%) without significantly affecting the evoked release of [14C]glutamate, [14C]5-hydroxytryptamine, [3H]dopamine or [3H] gamma-amino butyric acid.	Potassium	87-96	interleukin 2	Rattus norvegicus	25-29
8477053-5	1993	In addition, IL-2 increased the potassium-evoked release of methionine-enkephalin (by 78%) and beta-endorphin (by 38%) from hypothalamic slices without affecting the release of leucine-enkephalin.	Potassium	32-41	interleukin 2	Rattus norvegicus	13-17
7682299-5	1993	However, potassium-evoked depolarization and drugs that increase intracellular cyclic AMP concentrations (forskolin, 8-bromo cyclic AMP, isobutylmethylxanthine) interacted synergistically to stimulate high levels of VIP expression in newborn rat neurons.	Potassium	9-18	vasoactive intestinal peptide	Rattus norvegicus	216-219
8384511-1	1993	In the CA1 region of rat hippocampal slices, spreading depression (SD) was provoked by a brief period of hypoxia or by localized application of high potassium solution.	Potassium	149-158	carbonic anhydrase 1	Rattus norvegicus	7-10
8441823-5	1993	Results showed that ANF decreased bile flow and the excretion rate of sodium, potassium, chloride, bile acids, cholesterol and proteins.	Potassium	78-87	natriuretic peptide A	Rattus norvegicus	20-23
8094340-10	1993	Depolarization of cultures with high potassium, veratridine, or exposure to the excitatory neurotransmitter aspartate, resulted in a two- to threefold increase in the expression of both the p75 protein and messenger RNA.	Potassium	37-46	TNF receptor superfamily member 1B	Homo sapiens	190-193
7678819-1	1993	We have previously shown that the long-term alterations in the intake of sodium and potassium which stimulated aldosterone production in the rat adrenal significantly increased cytochrome P450scc (P450scc) and P45011 beta (P45011 beta) mRNA"s and also the mRNA of their electron donor adrenodoxin.	Potassium	84-93	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	177-195
7678819-1	1993	We have previously shown that the long-term alterations in the intake of sodium and potassium which stimulated aldosterone production in the rat adrenal significantly increased cytochrome P450scc (P450scc) and P45011 beta (P45011 beta) mRNA"s and also the mRNA of their electron donor adrenodoxin.	Potassium	84-93	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	188-195
7679407-5	1993	GH/IGF-I treatment resulted in substantial urinary potassium conservation (34 +/- 3 mmol/d, mean +/- SE; P < 0.001), suggesting that most protein accretion occurred in muscle and connective tissue.	Potassium	51-60	insulin like growth factor 1	Homo sapiens	3-8
7951496-2	1993	He had been treated with angiotensin converting enzyme inhibitor (ACEI) for 7 years and showed marked hypokalemia with increased urinary potassium excretion.	Potassium	137-146	angiotensin I converting enzyme	Homo sapiens	25-54
8425494-8	1993	In AN-ME incubations, ET-3 effects were enhanced by potassium-induced depolarization.	Potassium	52-61	endothelin 3	Homo sapiens	22-26
8441227-10	1993	In conclusion, ANP has both physiological and pharmacological significance in the control of potassium and urea metabolism by decreasing plasma levels of K+ and urea through effects on the renal excretory function.	Potassium	93-102	natriuretic peptide A	Homo sapiens	15-18
8381483-0	1993	Decreased erythrocyte Na+,K(+)-ATPase activity associated with cellular potassium loss in extremely low birth weight infants with nonoliguric hyperkalemia.	Potassium	72-81	dynein axonemal heavy chain 8	Homo sapiens	31-37
8381483-9	1993	Low Na+,K(+)-ATPase activity was associated with lower intracellular potassium/serum potassium ratios (p = 0.006), higher serum potassium values (p = 0.02), and lower intracellular potassium concentration (p = 0.009).	Potassium	69-78	dynein axonemal heavy chain 8	Homo sapiens	13-19
8381483-9	1993	Low Na+,K(+)-ATPase activity was associated with lower intracellular potassium/serum potassium ratios (p = 0.006), higher serum potassium values (p = 0.02), and lower intracellular potassium concentration (p = 0.009).	Potassium	85-94	dynein axonemal heavy chain 8	Homo sapiens	13-19
8381483-9	1993	Low Na+,K(+)-ATPase activity was associated with lower intracellular potassium/serum potassium ratios (p = 0.006), higher serum potassium values (p = 0.02), and lower intracellular potassium concentration (p = 0.009).	Potassium	85-94	dynein axonemal heavy chain 8	Homo sapiens	13-19
8381483-9	1993	Low Na+,K(+)-ATPase activity was associated with lower intracellular potassium/serum potassium ratios (p = 0.006), higher serum potassium values (p = 0.02), and lower intracellular potassium concentration (p = 0.009).	Potassium	85-94	dynein axonemal heavy chain 8	Homo sapiens	13-19
8386113-2	1993	The zona glomerulosa level of CYP11B2 mRNA was raised by potassium repletion or sodium restriction and was lowered by potassium depletion or by the administration of deoxycorticosterone, ACTH or dexamethasone.	Potassium	57-66	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	30-37
8386113-2	1993	The zona glomerulosa level of CYP11B2 mRNA was raised by potassium repletion or sodium restriction and was lowered by potassium depletion or by the administration of deoxycorticosterone, ACTH or dexamethasone.	Potassium	118-127	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	30-37
8432204-6	1993	CsA-induced hyperpolarization of lymphocytes was dependent on potassium ion (K+) efflux as indicated by the absence of hyperpolarization in 154 mM KCl or with pretreatment with 100 microM quinine (an inhibitor of K+ channels).	Potassium	62-71	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	0-3
8095426-0	1993	Perfusion with high potassium plus glutamate can cause LTP erasure or persistent loss of neuronal responsiveness in the CA1 region of the hippocampal slice.	Potassium	20-29	carbonic anhydrase 1	Rattus norvegicus	120-123
7907455-3	1993	However, later studies have shown that cholinesterase inhibitors also interact with cholinergic receptors, with sodium and potassium ion channels and effect the uptake, synthesis and release of neurotransmitters.	Potassium	123-132	butyrylcholinesterase	Homo sapiens	39-53
7907456-15	1993	Furthermore, GABA can readily be released upon potassium stimulation in the period preceding CA1 pyramidal cell death.	Potassium	47-56	carbonic anhydrase 1	Rattus norvegicus	93-96
8388847-5	1993	Beta 3-adrenoceptor stimulation may also have an effect on plasma potassium control since administration of selective beta 3-adrenoceptor agonists induces a decrease in plasma potassium.	Potassium	66-75	adrenoceptor beta 3	Homo sapiens	0-19
8467527-9	1993	Glucose induction of pyruvate decarboxylase, glucose-induced cAMP-signalling, glucose-induced inactivation of fructose-1,6-bisphosphatase, and glucose-induced activation of the potassium transport system, all deficient in ggs1 mutants, were restored by the deletion of HXK2.	Potassium	177-186	alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1	Saccharomyces cerevisiae S288C	222-226
8467527-9	1993	Glucose induction of pyruvate decarboxylase, glucose-induced cAMP-signalling, glucose-induced inactivation of fructose-1,6-bisphosphatase, and glucose-induced activation of the potassium transport system, all deficient in ggs1 mutants, were restored by the deletion of HXK2.	Potassium	177-186	hexokinase 2	Saccharomyces cerevisiae S288C	269-273
8477870-5	1993	(c) Exogenous hypophysial peptides (vasopressin, oxytocin, and alpha-, beta-, and gamma-MSH) stimulate increased potassium (and sodium) excretion.	Potassium	113-122	proopiomelanocortin	Rattus norvegicus	63-91
8388847-5	1993	Beta 3-adrenoceptor stimulation may also have an effect on plasma potassium control since administration of selective beta 3-adrenoceptor agonists induces a decrease in plasma potassium.	Potassium	66-75	adrenoceptor beta 3	Homo sapiens	118-137
8388847-5	1993	Beta 3-adrenoceptor stimulation may also have an effect on plasma potassium control since administration of selective beta 3-adrenoceptor agonists induces a decrease in plasma potassium.	Potassium	176-185	adrenoceptor beta 3	Homo sapiens	0-19
8388847-5	1993	Beta 3-adrenoceptor stimulation may also have an effect on plasma potassium control since administration of selective beta 3-adrenoceptor agonists induces a decrease in plasma potassium.	Potassium	176-185	adrenoceptor beta 3	Homo sapiens	118-137
8093260-3	1993	Levels of mGluR1 mRNA were decreased to less than half by high potassium stimulation and by glutamate and quisqualate.	Potassium	63-72	glutamate metabotropic receptor 1	Homo sapiens	10-16
8486330-0	1993	Neurotensin modulates differently potassium, veratridine and 4-aminopyridine-evoked release of dopamine in rat striatal slices.	Potassium	34-43	neurotensin	Rattus norvegicus	0-11
8071467-4	1993	Potassium excretion was significantly increased only at the two highest atrial natriuretic factor infusion rates.	Potassium	0-9	natriuretic peptide A	Gallus gallus	72-97
8383153-4	1993	After a wash-out period the patient was treated with salmon calcitonin with a net improvement of diarrhea, normalization of potassium serum level and reduction of VIP level.	Potassium	124-133	calcitonin related polypeptide alpha	Homo sapiens	60-70
8433561-4	1993	We tested the hypothesis that the infusion of physiologic doses of insulin prevents fasting hyperkalemia in hemodialysis patients, both by a direct stimulation of extrarenal potassium disposal, as well as by augmenting the potassium-lowering effect of epinephrine.	Potassium	174-183	insulin	Homo sapiens	67-74
8433561-4	1993	We tested the hypothesis that the infusion of physiologic doses of insulin prevents fasting hyperkalemia in hemodialysis patients, both by a direct stimulation of extrarenal potassium disposal, as well as by augmenting the potassium-lowering effect of epinephrine.	Potassium	223-232	insulin	Homo sapiens	67-74
8381931-4	1993	Insulin infusion reduced both the absolute and fractional urinary excretion rates of sodium (P < 0.001) and potassium (P < 0.001); these effects of insulin were not altered after converting enzyme inhibition.	Potassium	111-120	insulin	Homo sapiens	0-7
8381931-4	1993	Insulin infusion reduced both the absolute and fractional urinary excretion rates of sodium (P < 0.001) and potassium (P < 0.001); these effects of insulin were not altered after converting enzyme inhibition.	Potassium	111-120	insulin	Homo sapiens	154-161
8095702-0	1993	Induction of c-FOS immunoreactivity in the hippocampus following potassium stimulation.	Potassium	65-74	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	13-18
7906427-0	1993	D1 and D2 dopamine receptor modulation of sodium and potassium currents in rat neostriatal neurons.	Potassium	53-62	dopamine receptor D2	Rattus norvegicus	7-27
1465596-6	1992	However, long-term ACE inhibition may be accompanied by a worsening of hyperkalemia, which could be accounted for by a reduced effect of aldosterone on extrarenal potassium homeostasis.	Potassium	163-172	angiotensin I converting enzyme	Homo sapiens	19-22
1362521-0	1992	MK-801 affects the potassium-induced increase of glial fibrillary acidic protein immunoreactivity in rat brain.	Potassium	19-28	glial fibrillary acidic protein	Rattus norvegicus	49-80
1333446-4	1992	The effects of adrenocorticotropic hormone or potassium on adrenal zona glomerulosa cell renin activity and renin mRNA content were compared with the activity and content of control cells.	Potassium	46-55	renin	Rattus norvegicus	89-94
1334753-2	1992	The effect of agents which interact with the histamine H3 receptor on potassium-stimulated tritium release from slices of rat entorhinal cortex preloaded with [3H]-choline is described.	Potassium	70-79	histamine receptor H3	Rattus norvegicus	45-66
1286529-0	1992	Effect of potassium infusion on renal function in ANF-transgenic mice.	Potassium	10-19	natriuretic peptide type A	Mus musculus	50-53
1333446-5	1992	After 1 and 4 hours of stimulation by adrenocorticotropic hormone or potassium, total renin in the medium increased slightly; at the same time, the percent change in the amount of renin mRNA was 281% and 291%, respectively, in the adrenocorticotropic hormone-stimulated group and 218% and 348%, respectively, in the potassium-stimulated group.	Potassium	69-78	renin	Rattus norvegicus	86-91
1333446-6	1992	Twenty-four hours after adrenocorticotropic hormone or potassium stimulation, total renin in the medium increased significantly, by 689% and 220%, respectively; percent change in the renin mRNA content was 754% and 278%, respectively.	Potassium	55-64	renin	Rattus norvegicus	84-89
1333446-6	1992	Twenty-four hours after adrenocorticotropic hormone or potassium stimulation, total renin in the medium increased significantly, by 689% and 220%, respectively; percent change in the renin mRNA content was 754% and 278%, respectively.	Potassium	55-64	renin	Rattus norvegicus	183-188
1333446-7	1992	These results demonstrate that adrenocorticotropic hormone and potassium increased the activity of adrenal renin through an increase in the level of renin mRNA.	Potassium	63-72	renin	Rattus norvegicus	107-112
1333446-7	1992	These results demonstrate that adrenocorticotropic hormone and potassium increased the activity of adrenal renin through an increase in the level of renin mRNA.	Potassium	63-72	renin	Rattus norvegicus	149-154
1281495-4	1992	In neuronal cultures of the rat hippocampus, potassium depolarization and kainic acid-mediated increases in BDNF and NGF mRNA were eliminated in a dose-dependent manner by the calcium channel blocker nifedipine.	Potassium	45-54	brain-derived neurotrophic factor	Rattus norvegicus	108-112
1337105-7	1992	The characteristic CA1 spike afterdepolarization was a consequence of the longitudinal spread of dendritic charge, reactivation of slow Ca(2+)-dependent K+ conductances, slow synaptic processes (NMDA-dependent depolarizing and gamma-aminobutyric acid-mediated hyperpolarizing currents) and was sensitive to extracellular potassium accumulation.	Potassium	321-330	carbonic anhydrase 1	Homo sapiens	19-22
1294423-3	1992	Venous plasma concentrations of ANP were also studied in relation to urinary sodium and potassium excretion, as well as the renin-angiotensin-aldosterone system.	Potassium	88-97	natriuretic peptide A	Homo sapiens	32-35
1336526-11	1992	Plasma renin activity increased and body weight fell after potassium supplementation.	Potassium	59-68	renin	Homo sapiens	7-12
22217827-2	1992	Low sodium and high potassium intake promoted time-dependent increases in the zona glomerulosa cytochrome P450scc (P450scc) and cytochrome P450c11 (P450c11) protein and mRNA levels, but no changes were found in the zona fasciculata-reticularis.	Potassium	20-29	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	95-113
22217827-2	1992	Low sodium and high potassium intake promoted time-dependent increases in the zona glomerulosa cytochrome P450scc (P450scc) and cytochrome P450c11 (P450c11) protein and mRNA levels, but no changes were found in the zona fasciculata-reticularis.	Potassium	20-29	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	106-113
22217827-2	1992	Low sodium and high potassium intake promoted time-dependent increases in the zona glomerulosa cytochrome P450scc (P450scc) and cytochrome P450c11 (P450c11) protein and mRNA levels, but no changes were found in the zona fasciculata-reticularis.	Potassium	20-29	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	139-146
22217827-2	1992	Low sodium and high potassium intake promoted time-dependent increases in the zona glomerulosa cytochrome P450scc (P450scc) and cytochrome P450c11 (P450c11) protein and mRNA levels, but no changes were found in the zona fasciculata-reticularis.	Potassium	20-29	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	148-155
22217827-12	1992	In conclusion, this work demonstrates that variations in the intake of sodium and potassium act on the expression of the CYP11B2 gene, but not on that of the CYP11B1 gene.	Potassium	82-91	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	121-128
1472982-2	1992	The transient potassium current was recorded in single hippocampal CA1 neurones from the rat by use of the whole-cell patch clamp technique.	Potassium	14-23	carbonic anhydrase 1	Rattus norvegicus	67-70
1330655-0	1992	Modulation of potassium transport in cultured retinal pigment epithelium and retinal glial cells by serum and epidermal growth factor.	Potassium	14-23	epidermal growth factor	Homo sapiens	110-133
1329558-0	1992	Vasopressin resistance in potassium depletion: role of Na-K pump.	Potassium	26-35	arginine vasopressin	Rattus norvegicus	0-11
1396339-7	1992	In the primary monolayer culture of glomerulosa cells, TGR cells had significantly higher levels of active renin and prorenin and showed an increased response to ACTH and high potassium in the medium.	Potassium	176-185	thioredoxin reductase 3	Mus musculus	55-58
1331814-0	1992	Potentiation of potassium-evoked noradrenaline and neuropeptide Y co-release by cardiac energy depletion: role of calcium channels and sodium-proton exchange.	Potassium	16-25	pro-neuropeptide Y	Cavia porcellus	51-65
1396339-11	1992	In conclusion, the TGR (mRen-2)27 rats have higher than normal levels of adrenal renin, and the cultured cells show an exaggerated renin response to ACTH and potassium.	Potassium	158-167	renin	Rattus norvegicus	131-136
1403796-1	1992	5-hydroxytryptamine (5-HT) hyperpolarizes hippocampal pyramidal cells in both areas CA1 and CA3 through an increase in potassium conductance.	Potassium	119-128	carbonic anhydrase 3	Homo sapiens	92-95
1331814-1	1992	The role of the cardiac energy status in the potassium-evoked exocytosis of both noradrenaline and the sympathetic co-transmitter neuropeptide Y (NPY) was investigated in the guinea-pig perfused heart.	Potassium	45-54	pro-neuropeptide Y	Cavia porcellus	130-144
1331814-1	1992	The role of the cardiac energy status in the potassium-evoked exocytosis of both noradrenaline and the sympathetic co-transmitter neuropeptide Y (NPY) was investigated in the guinea-pig perfused heart.	Potassium	45-54	pro-neuropeptide Y	Cavia porcellus	146-149
1331814-5	1992	Under normoxic conditions potassium depolarization evoked a co-release of both transmitters [molar ratio 862 (noradrenaline):1 (NPY)] at a threshold concentration of 40 mmol/l potassium.	Potassium	26-35	pro-neuropeptide Y	Cavia porcellus	128-131
1331814-5	1992	Under normoxic conditions potassium depolarization evoked a co-release of both transmitters [molar ratio 862 (noradrenaline):1 (NPY)] at a threshold concentration of 40 mmol/l potassium.	Potassium	176-185	pro-neuropeptide Y	Cavia porcellus	128-131
1331814-8	1992	In comparison to normoxia, a 10-fold increased transmitter overflow with a comparable molar ratio [709 (noradrenaline:1 (NPY)] was evoked by 40 mmol/l potassium after 10 min of either anoxia or cyanide intoxication.	Potassium	151-160	pro-neuropeptide Y	Cavia porcellus	121-124
1505513-7	1992	In cells overexpressing HAL1, sodium toxicity seems to be counteracted by an increased accumulation of potassium.	Potassium	103-112	Hal1p	Saccharomyces cerevisiae S288C	24-28
1472949-8	1992	IGF-I binding was inhibited by a variety of salts in a dose-dependent manner, calcium and magnesium salts being more effective than sodium or potassium salts.	Potassium	142-151	insulin like growth factor 1	Homo sapiens	0-5
1440976-5	1992	To our knowledge, this is the first report in which a lack of MADA and chronic licorice intoxication has been shown to be associated with clinical, histochemical, biochemical, and morphological changes, which were completely reversed with potassium supplementation and licorice withdrawal.	Potassium	239-248	adenosine monophosphate deaminase 3	Homo sapiens	62-66
1522239-6	1992	The HCO3(-)-dependent pHi recovery was inhibited by raising extracellular potassium concentration and by intracellular potassium depletion.	Potassium	74-83	glucose-6-phosphate isomerase	Rattus norvegicus	22-25
1522239-6	1992	The HCO3(-)-dependent pHi recovery was inhibited by raising extracellular potassium concentration and by intracellular potassium depletion.	Potassium	119-128	glucose-6-phosphate isomerase	Rattus norvegicus	22-25
1354394-0	1992	A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents.	Potassium	69-78	adrenergic receptor, alpha 2a	Mus musculus	32-44
1327406-6	1992	Subsequent stimulation with 10(-6) M CRH showed a desensitization to stimulation despite readily releasable pools of IR-beta-END shown by potassium-induced depolarization.	Potassium	138-147	corticotropin releasing hormone	Rattus norvegicus	37-40
1354394-1	1992	The alpha 2A-adrenergic receptor (adrenoceptor) was stably expressed in AtT20 mouse pituitary tumor cells; adrenoceptor agonists inhibited adenylyl cyclase, inhibited voltage-dependent calcium currents, and increased inwardly rectifying potassium currents.	Potassium	237-246	adrenergic receptor, alpha 2a	Mus musculus	4-47
1354394-1	1992	The alpha 2A-adrenergic receptor (adrenoceptor) was stably expressed in AtT20 mouse pituitary tumor cells; adrenoceptor agonists inhibited adenylyl cyclase, inhibited voltage-dependent calcium currents, and increased inwardly rectifying potassium currents.	Potassium	237-246	adrenergic receptor, alpha 2a	Mus musculus	34-46
1637215-6	1992	The data reflect the beneficial effect associated with the action of glucose-insulin-potassium on myocardial protection during heart operations and were confirmed by the hemodynamic results.	Potassium	85-94	insulin	Homo sapiens	77-84
1639459-12	1992	In the urine, the ratio of the fractional excretion of potassium to that of sodium was decreased by both oral glucose (-22%, p less than 0.01) and ACE inhibition (-21%, p less than 0.001).	Potassium	55-64	angiotensin I converting enzyme	Homo sapiens	147-150
1637215-2	1992	The hemodynamic parameters measured before and after administration of the solution, after cardiopulmonary bypass, after administration of protamine, and 3 hours after leaving the operating room showed the beneficial effect of the glucose-insulin-potassium infusion on cardiac index (+23.6% after protamine infusion) and left (+16.3% 3 hours postoperatively) and right (+47.3% after cardiopulmonary bypass) ventricular workload index with a decrease in systemic vascular resistance.	Potassium	247-256	insulin	Homo sapiens	239-246
1637215-5	1992	Laboratory tests showed that postoperative hypoglycemia was more common in the glucose-insulin-potassium group but had no detrimental effects; it no longer occurs since we began administering the glucose infusion at 15 g/h over 8 hours.	Potassium	95-104	insulin	Homo sapiens	87-94
1356568-0	1992	Strychnine-induced potassium current in CA1 pyramidal neurones of the rat hippocampus.	Potassium	19-28	carbonic anhydrase 1	Rattus norvegicus	40-43
1639459-13	1992	Higher plasma potassium levels before treatment predicted a better blood pressure response to ACE inhibition (r = 0.60, p less than 0.005).	Potassium	14-23	angiotensin I converting enzyme	Homo sapiens	94-97
1379246-3	1992	Both potassium depolarization and agonist-induced activation of calcium channels promoted substantial neurite outgrowth from PC12 cells cultured on control 3T3 monolayers and increased neurite outgrowth from those cultured on N-cadherin-expressing 3T3 monolayers.	Potassium	5-14	cadherin 2	Rattus norvegicus	226-236
1429916-5	1992	This suggests that in asthmatic subjects on beta 2-agonist treatment, plasma potassium could be used as a surrogate marker for beta 2 activity at bronchi.	Potassium	77-86	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	44-50
1386372-0	1992	Effect of atrial natriuretic peptide on potassium-stimulated aldosterone secretion: potential relevance to hypoaldosteronism in man.	Potassium	40-49	natriuretic peptide A	Homo sapiens	10-36
1386372-8	1992	Endogenous ANP levels in the hyperkalemic patients with hypoaldosteronism were markedly elevated at 1186 +/- 340 pmol/L (compared to 93 +/- 10 pmol/L in healthy elderly controls), a level that would be capable of suppressing the potassium-mediated aldosterone response.	Potassium	229-238	natriuretic peptide A	Homo sapiens	11-14
1429916-5	1992	This suggests that in asthmatic subjects on beta 2-agonist treatment, plasma potassium could be used as a surrogate marker for beta 2 activity at bronchi.	Potassium	77-86	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	127-133
1429916-6	1992	It also implies that the most effective beta 2-agonist bronchodilators will produce the greatest fall in plasma potassium.	Potassium	112-121	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	40-46
1331651-2	1992	Recently, we have shown that the connecting peptides prepro-TRH-(160-169) (Ps4) and prepro-TRH-(178-199) (Ps5) are released from rat hypothalamic neurones in response to elevated potassium concentrations, in a calcium-dependent manner.	Potassium	179-188	thyrotropin releasing hormone	Rattus norvegicus	60-63
1378491-4	1992	Neurotensin levels were up-regulated by elevated potassium, forskolin, and phorbol ester in bovine chromaffin cells.	Potassium	49-58	neurotensin	Bos taurus	0-11
1353613-1	1992	Opioid agonists specific for the mu, delta, and kappa opioid receptor subtypes were tested for their ability to modulate potassium-evoked release of L-glutamate and dynorphin B-like immunoreactivity from guinea pig hippocampal mossy fiber synaptosomes.	Potassium	121-130	mu-type opioid receptor	Cavia porcellus	33-69
1355004-2	1992	Hyperpolarization is caused by an increased potassium conductance that is attenuated by glibenclamide (1-10 microM), a selective antagonist of ATP-sensitive potassium channels; in contrast, diazoxide (0.5 mM), an agonist at this channel, induces a hyperpolarization in CA1 neurons of rat hippocampal slices.	Potassium	44-53	carbonic anhydrase 1	Rattus norvegicus	269-272
1331651-2	1992	Recently, we have shown that the connecting peptides prepro-TRH-(160-169) (Ps4) and prepro-TRH-(178-199) (Ps5) are released from rat hypothalamic neurones in response to elevated potassium concentrations, in a calcium-dependent manner.	Potassium	179-188	thyrotropin releasing hormone	Rattus norvegicus	91-94
1318793-9	1992	The bradykinin-induced hyperpolarization and NLA-resistant relaxations were transient and impaired by potassium depolarization.	Potassium	102-111	kininogen 1	Canis lupus familiaris	4-14
1504913-0	1992	The antiarrhythmic effect of the ACE inhibitor captopril in patients with congestive heart failure largely is due to its potassium sparing effects.	Potassium	121-130	angiotensin I converting enzyme	Homo sapiens	33-36
1504913-11	1992	CONCLUSIONS: As the only obvious difference between this and previous studies that documented a decrease in ventricular arrhythmias when ACE inhibitors were started in patients with congestive heart failure is a lack of change in serum potassium in this study, the current results suggest that the major antiarrhythmic effect of ACE inhibitors in patients with congestive hear failure is the result of their potassium sparing effects.	Potassium	408-417	angiotensin I converting enzyme	Homo sapiens	137-140
1355975-0	1992	Effects of the beta-adrenergic agonist, ritodrine, and insulin on plasma potassium concentrations in fetal lambs.	Potassium	73-82	LOC105613195	Ovis aries	55-62
1641867-4	1992	Fractional excretion of sodium showed a significant correlation with age in all the subjects, while that of potassium significantly correlated with serum beta 2-microglobulin.	Potassium	108-117	beta-2-microglobulin	Homo sapiens	154-174
1355050-4	1992	Depolarization with potassium induced an increase in the VP peptide secreted of 2.2-fold, with no effect on the VP mRNA content or size.	Potassium	20-29	arginine vasopressin	Rattus norvegicus	57-59
1637082-3	1992	High potassium releases CGRP, and this release, as well as the tissue concentration of CGRP in the amygdala, can be influenced by neuroleptic drugs.	Potassium	5-14	calcitonin	Gallus gallus	24-28
1597135-0	1992	Dietary potassium supplementation and sodium restriction stimulate aldosterone synthase but not 11 beta-hydroxylase P-450 messenger ribonucleic acid accumulation in rat adrenals and require angiotensin II production.	Potassium	8-17	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	67-87
1597135-0	1992	Dietary potassium supplementation and sodium restriction stimulate aldosterone synthase but not 11 beta-hydroxylase P-450 messenger ribonucleic acid accumulation in rat adrenals and require angiotensin II production.	Potassium	8-17	angiotensinogen	Rattus norvegicus	190-204
1597135-9	1992	High potassium or low sodium diet given to rats for 1 week increased aldosterone synthase P-450 mRNA levels by approximately 5- and 6-fold, respectively.	Potassium	5-14	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	69-89
1597135-13	1992	Finally, captopril inhibited potassium induction of aldosterone synthase P-450 mRNA levels despite the presence of low plasma renin activity in the potassium-treated rats.	Potassium	29-38	cytochrome P450, family 11, subfamily b, polypeptide 2	Rattus norvegicus	52-72
1597135-14	1992	This finding implicates intraadrenal angiotensin II formation in the effect of potassium on mineralocorticoid production.	Potassium	79-88	angiotensinogen	Rattus norvegicus	37-51
1506004-3	1992	The results from these studies, reviewed herein, indicate that KS is a cytokine-mediated disease and that inflammatory and angiogenic cytokines and the HIV-1 Tat protein cooperate in its induction and progression in HIV-1-infected individuals.	Potassium	63-65	Tat	Human immunodeficiency virus 1	158-161
1377873-0	1992	Insulin-like growth factor I in initial renal hypertrophy in potassium-depleted rats.	Potassium	61-70	insulin-like growth factor 1	Rattus norvegicus	0-28
1631174-13	1992	The data suggest that a pathophysiologically critical degree of potassium depletion is associated with an inhibited renal prostanoid synthesis as well as an increased renin secretion.	Potassium	64-73	renin	Homo sapiens	167-172
1326745-0	1992	Endothelin-1 stimulates chloride and potassium secretion in rabbit descending colon.	Potassium	37-46	endothelin-1	Oryctolagus cuniculus	0-12
1354553-1	1992	We observed that a transient increase in extracellular potassium concentration (50 mM for 40 s) was sufficient to induce long-term potentiation (LTP) of synaptic transmission in area CA1 of the hippocampal slice.	Potassium	55-64	carbonic anhydrase 1	Rattus norvegicus	183-186
1374241-0	1992	Hypotonic solution increases the slowly activating potassium current IsK expressed in xenopus oocytes.	Potassium	51-60	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	69-72
1315978-5	1992	The relaxing capacity of ET-1 was absent when the tissue was precontracted by potassium yet was resistant to pretreatments with tetrodotoxin, capsaicin, propranolol, indomethacin, NG-methyl-L-arginine or glibenclamide.	Potassium	78-87	endothelin 1	Rattus norvegicus	25-29
1318799-10	1992	We conclude that the highly heterogeneous distribution of connexin43-immunoreactivity among defined nuclear structures in adult brain does not reflect an antecedent requirement for connexin43 in early brain morphogenesis, but rather is related to the development of neuronal activity, the establishment of functional circuitry and the contribution of astrocytic gap junctions to glial metabolic coupling and potassium spatial buffering in the mature CNS.	Potassium	408-417	gap junction protein, alpha 1	Rattus norvegicus	58-68
1407658-4	1992	The phospholipase A2 inhibitor, 4-bromophenacylbromide (BPB), and nordihydroguaiaretic acid (NDGA), an inhibitor of arachidonic acid metabolism, but not indomethacin, block FMRFamide"s activation of the potassium current.	Potassium	203-212	phospholipase A2 group IB	Homo sapiens	4-20
1312445-8	1992	Aldosterone was also stimulated by high doses of potassium, and potassium had a stimulatory effect on the secretion of renin in medium.	Potassium	64-73	renin	Bos taurus	119-124
1589596-12	1992	Under in vitro conditions basal and potassium induced TRH release from SMEs derived from SHR was significantly (P less than 0.05) higher than that from WKY rats, whether expressed in absolute terms or as percent of content.	Potassium	36-45	thyrotropin releasing hormone	Rattus norvegicus	54-57
1348274-5	1992	In the mesencephalic cultures, NT increased potassium-evoked release of tritiated dopamine, and the relative potencies of various NT-related peptides to increase dopamine release were in good agreement with their abilities to bind to NT sites.	Potassium	44-53	neurotensin	Rattus norvegicus	31-33
1547736-0	1992	The role of protein kinase-C in control of aldosterone production by rat adrenal glomerulosa cells: activation of protein kinase-C by stimulation with potassium.	Potassium	151-160	protein kinase C, gamma	Rattus norvegicus	12-28
1547736-0	1992	The role of protein kinase-C in control of aldosterone production by rat adrenal glomerulosa cells: activation of protein kinase-C by stimulation with potassium.	Potassium	151-160	protein kinase C, gamma	Rattus norvegicus	114-130
1619503-0	1992	Potassium as a link between insulin and the renin-angiotensin-aldosterone system.	Potassium	0-9	insulin	Homo sapiens	28-35
1619503-0	1992	Potassium as a link between insulin and the renin-angiotensin-aldosterone system.	Potassium	0-9	renin	Homo sapiens	44-49
1619503-2	1992	EFFECTS ON INSULIN: Insulin is a potent stimulus for hypokalaemia, sparing body potassium from urinary excretion by transporting it into cells.	Potassium	80-89	insulin	Homo sapiens	11-18
1619503-2	1992	EFFECTS ON INSULIN: Insulin is a potent stimulus for hypokalaemia, sparing body potassium from urinary excretion by transporting it into cells.	Potassium	80-89	insulin	Homo sapiens	20-27
1619503-3	1992	Potassium also appears to play a key role in the antinatriuretic effect of insulin.	Potassium	0-9	insulin	Homo sapiens	75-82
1619503-5	1992	In turn, the renin-angiotensin-aldosterone system affects glucose tolerance by modulating plasma potassium levels, which act as a stimulus for glucose-induced insulin release.	Potassium	97-106	renin	Homo sapiens	13-18
1619503-5	1992	In turn, the renin-angiotensin-aldosterone system affects glucose tolerance by modulating plasma potassium levels, which act as a stimulus for glucose-induced insulin release.	Potassium	97-106	insulin	Homo sapiens	159-166
1619503-9	1992	In addition, in patients with essential hypertension, the level of plasma potassium appears to predict the blood pressure response to ACE inhibition.	Potassium	74-83	angiotensin I converting enzyme	Homo sapiens	134-137
1619503-10	1992	SUMMARY: Potassium metabolism is an important link between carbohydrate metabolism and the renin-angiotensin-aldosterone system by way of a double-feedback mechanism.	Potassium	9-18	renin	Homo sapiens	91-96
1549610-3	1992	Here we describe that superfusion of cultured rat hippocampal neurones with potassium-free medium leads to a decrease of a specific outward potassium current, probably carried by RCK4-type channels (RCK4 are potassium channels found in rat brain).	Potassium	76-85	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	199-203
1619503-11	1992	Through the potential effects on blood pressure control, plasma levels of potassium represent a link between insulin and blood pressure in humans.	Potassium	74-83	insulin	Homo sapiens	109-116
1549610-3	1992	Here we describe that superfusion of cultured rat hippocampal neurones with potassium-free medium leads to a decrease of a specific outward potassium current, probably carried by RCK4-type channels (RCK4 are potassium channels found in rat brain).	Potassium	76-85	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	179-183
1549610-3	1992	Here we describe that superfusion of cultured rat hippocampal neurones with potassium-free medium leads to a decrease of a specific outward potassium current, probably carried by RCK4-type channels (RCK4 are potassium channels found in rat brain).	Potassium	140-149	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	179-183
1549610-3	1992	Here we describe that superfusion of cultured rat hippocampal neurones with potassium-free medium leads to a decrease of a specific outward potassium current, probably carried by RCK4-type channels (RCK4 are potassium channels found in rat brain).	Potassium	140-149	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	199-203
1549610-7	1992	The potassium dependence of macroscopic conductance in RCK4 channels was related by site-directed mutagenesis to that lysine residue in the extracellular loop between the transmembrane segments S5 and S6 of RCK4 protein that confers resistance to extracellular blockage by tetraethylammonium.	Potassium	4-13	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	55-59
1549610-7	1992	The potassium dependence of macroscopic conductance in RCK4 channels was related by site-directed mutagenesis to that lysine residue in the extracellular loop between the transmembrane segments S5 and S6 of RCK4 protein that confers resistance to extracellular blockage by tetraethylammonium.	Potassium	4-13	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	207-211
1549610-8	1992	It is shown that extracellular potassium affects the number of available RCK4 channels, but not the single-channel conductance, the mean open time, or the gating charge displacement upon depolarization.	Potassium	31-40	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	73-77
1554376-0	1992	Angiotensin II exerts its effect on aldosterone production and potassium permeability through receptor subtype AT1 in rat adrenal glomerulosa cells.	Potassium	63-72	angiotensinogen	Rattus norvegicus	0-14
1542793-4	1992	Oncostatin M RNA and immunoreactive Oncostatin M protein were found in AIDS-KS-derived cell isolates.	Potassium	76-78	oncostatin M	Homo sapiens	0-12
1542793-4	1992	Oncostatin M RNA and immunoreactive Oncostatin M protein were found in AIDS-KS-derived cell isolates.	Potassium	76-78	oncostatin M	Homo sapiens	36-48
1538559-12	1992	As with the weight loss diet, patients on a low sodium/high potassium diet in the highest baseline renin index quartile had a greater reduction in DBP than patients in the lowest baseline renin index quartile.	Potassium	60-69	renin	Homo sapiens	99-104
1554376-0	1992	Angiotensin II exerts its effect on aldosterone production and potassium permeability through receptor subtype AT1 in rat adrenal glomerulosa cells.	Potassium	63-72	angiotensin II receptor, type 1a	Rattus norvegicus	111-114
1312512-10	1992	High potassium-stimulated renin production was not inhibited by Ang II.	Potassium	5-14	renin	Rattus norvegicus	26-31
1628142-16	1992	We conclude that in these cells, BRL 38227 activates a potassium conductance which has the electrophysiological and pharmacological characteristics of ATP-sensitive K+ channels.	Potassium	55-64	bromodomain containing 1	Homo sapiens	33-36
1547020-4	1992	RNA transcribed in vitro from HGK5 genomic DNA directs expression of functional voltage-dependent potassium currents in Xenopus oocytes.	Potassium	98-107	potassium voltage-gated channel subfamily A member 3	Homo sapiens	30-34
1547020-8	1992	Mitogenic concentrations of concanavalin A induced a time-dependent decrease in HGK5 mRNA levels, suggesting that previously observed increases in potassium current density following concanavalin A treatment of human T lymphocytes are not due to increased transcriptional activity of the type n potassium channel gene.	Potassium	147-156	potassium voltage-gated channel subfamily A member 3	Homo sapiens	80-84
1597305-7	1992	In addition, a hierarchy of selective pressure among the different H-2K haplotypes was present, such as Ks,b greater than Ks/q,k greater than Kq.	Potassium	104-106	histocompatibility 2, K1, K region	Mus musculus	67-71
1597305-7	1992	In addition, a hierarchy of selective pressure among the different H-2K haplotypes was present, such as Ks,b greater than Ks/q,k greater than Kq.	Potassium	122-124	histocompatibility 2, K1, K region	Mus musculus	67-71
1545141-2	1992	Enhancing the flux of potassium ions is a mechanism shared by several structurally diverse antihypertensive agents including minoxidil sulfate (the active metabolite of minoxidil), pinacidil, P-1075 (a potent pinacidil analog), RP-49,356, diazoxide, cromakalim, and nicorandil.	Potassium	22-31	cyclic nucleotide gated channel subunit alpha 1	Homo sapiens	228-233
1627756-4	1992	Potassium may also influence the regulation of blood pressure through effects on sodium handling, aldosterone secretion, the renin/angiotensin system, renal kallikrein, eicosanoids, and atrial natriuretic peptide.	Potassium	0-9	renin	Homo sapiens	125-130
1373958-1	1992	In the presence of potassium (K+), A23187 and substance P elicited endothelium-dependent relaxations of porcine coronary arteries.	Potassium	19-28	tachykinin precursor 1	Homo sapiens	46-57
1560570-2	1992	The present study was performed to see whether renin-aldosterone effect is involved in this inhibition of potassium excretion.	Potassium	106-115	renin	Homo sapiens	47-52
1572065-1	1992	Hippocampal CA3 pyramidal neurons in the adult epileptic mutant mouse tottering (tg) show normal intrinsic membrane properties, yet fire abnormally prolonged paroxysmal depolarizing shifts (PDS) during in vitro exposure to elevated extracellular potassium solutions.	Potassium	246-255	carbonic anhydrase 3	Mus musculus	12-15
1531208-3	1992	In the rat, intraperitoneal injections of pepsanurin (0.5 ml/100 g body wt) significantly inhibited the effects of an intravenous bolus of atrial natriuretic peptide (ANP) (0.5 micrograms) on water, sodium, and potassium excretion without altering systemic blood pressure.	Potassium	211-220	natriuretic peptide A	Rattus norvegicus	139-165
1598595-1	1992	Leakage of intracellular potassium and GPT in normal rat hepatocytes exposed to 10, 15 and 20 mmol/L of carbon tetrachloride (CCl4) in vitro was determined at 5, 10, 15 and 20 min after cell intoxication.	Potassium	25-34	C-C motif chemokine ligand 4	Rattus norvegicus	126-130
1558877-3	1992	For immunochemical properties, the low-molecular-mass protein A was similar to protein A isolated from S. aureus Cowan I. Extracellular protease activity of KS 1034 strain was considerably lower than S. aureus C-30 isolated from chicken that produced the extracellular low-molecular-mass protein A.	Potassium	157-159	G protein-coupled receptor 162	Gallus gallus	54-63
1558877-3	1992	For immunochemical properties, the low-molecular-mass protein A was similar to protein A isolated from S. aureus Cowan I. Extracellular protease activity of KS 1034 strain was considerably lower than S. aureus C-30 isolated from chicken that produced the extracellular low-molecular-mass protein A.	Potassium	157-159	G protein-coupled receptor 162	Gallus gallus	79-88
1558877-3	1992	For immunochemical properties, the low-molecular-mass protein A was similar to protein A isolated from S. aureus Cowan I. Extracellular protease activity of KS 1034 strain was considerably lower than S. aureus C-30 isolated from chicken that produced the extracellular low-molecular-mass protein A.	Potassium	157-159	G protein-coupled receptor 162	Gallus gallus	79-88
1623167-3	1992	Application of exogenous IL-2 to striatal slices in in vitro produced significant increases in both spontaneous and potassium (25 mM)-evoked [3H] dopamine release.	Potassium	116-125	interleukin 2	Rattus norvegicus	25-29
1598595-2	1992	Both of the intracellular potassium and GPT were clearly dose- and time-dependent with CCl4, but the leakage of intracellular potassium is a more sensitive index to indicate cell injury than the later.	Potassium	26-35	C-C motif chemokine ligand 4	Rattus norvegicus	87-91
1598595-2	1992	Both of the intracellular potassium and GPT were clearly dose- and time-dependent with CCl4, but the leakage of intracellular potassium is a more sensitive index to indicate cell injury than the later.	Potassium	126-135	C-C motif chemokine ligand 4	Rattus norvegicus	87-91
1598595-3	1992	The percent change of intracellular potassium in regenerating rat hepatocytes 20 min after CCl4 (15 mmol/L) intoxication was markedly reduced than that in normal rat.	Potassium	36-45	C-C motif chemokine ligand 4	Rattus norvegicus	91-95
1601058-0	1992	5-HT1A receptors activate a potassium conductance in rat ventromedial hypothalamic neurones.	Potassium	28-37	5-hydroxytryptamine receptor 1A	Rattus norvegicus	0-6
1737576-5	1992	Intravenous administration of PYY produced a dose-dependent increase in the net absorption of sodium chloride and water, as well as a decrease in the net secretion of potassium.	Potassium	167-176	peptide YY	Rattus norvegicus	30-33
1352037-1	1992	The 98 amino acid (a.a.) N-terminus of the 126 a.a. atrial natriuretic factor (ANF) prohormone contains three peptides consisting of a.a. 1-30 (proANF 1-30), a.a. 31-67 (proANF 31-67) and a.a. 79-98 (proANF 79-98) with blood pressure lowering, sodium and/or potassium excreting properties similar to atrial natriuretic factor (a.a. 99-126, C-terminus of prohormone).	Potassium	258-267	natriuretic peptide A	Homo sapiens	52-77
1352037-1	1992	The 98 amino acid (a.a.) N-terminus of the 126 a.a. atrial natriuretic factor (ANF) prohormone contains three peptides consisting of a.a. 1-30 (proANF 1-30), a.a. 31-67 (proANF 31-67) and a.a. 79-98 (proANF 79-98) with blood pressure lowering, sodium and/or potassium excreting properties similar to atrial natriuretic factor (a.a. 99-126, C-terminus of prohormone).	Potassium	258-267	natriuretic peptide A	Homo sapiens	79-82
1601058-5	1992	5-HT1A receptors likely activate a potassium conductance on these neurones.	Potassium	35-44	5-hydroxytryptamine receptor 1A	Rattus norvegicus	0-6
1374925-4	1992	With concentrations of capsaicin within this range the slow decline of the peptide release in the presence of capsaicin was not a consequence of exhaustion of an available peptide pool nor of neuronal impairment because potassium depolarization was still able to release CGRP.	Potassium	220-229	calcitonin-related polypeptide alpha	Rattus norvegicus	271-275
1727635-5	1992	Depletion of cellular potassium, which blocks formation of coated vesicles at the cell surface, stimulated asialo-TfR resialylation by 60% over controls, suggesting that coated vesicle formation is not the rate-limiting step in cell surface-to-Golgi transport.	Potassium	22-31	transferrin receptor	Homo sapiens	114-117
1733294-0	1992	Effect of insulin on potassium secretion in rabbit cortical collecting ducts.	Potassium	21-30	insulin	Oryctolagus cuniculus	10-17
1295687-1	1992	Two sets of new observations are reported: (i) astrocytes in primary cultures show an increased potassium-induced swelling in the presence of 1-100 x 10(-12) M vasopressin, whereas no similar phenomenon is found in primary cultures of neurons, and (ii) the furosemide-sensitive cotransport system for uptake of K+, Na+, and Cl-, which is known to exist in astrocytes, is absent in neurons.	Potassium	96-105	arginine vasopressin	Homo sapiens	160-171
1312204-0	1992	Long-term expression of the c-fos protein during the in vitro differentiation of cerebellar granule cells induced by potassium or NMDA.	Potassium	117-126	FBJ osteosarcoma oncogene	Mus musculus	28-33
1363942-2	1992	Like some drugs which do not exhibit any analgetic effect, promedol, analgin, clonidine, vasopressin and calcitonin also block the electrosensitive delayed potassium current.	Potassium	156-165	arginine vasopressin	Homo sapiens	89-100
1338301-0	1992	Adrenergic receptors (alpha 1 and alpha 2) modulate different potassium conductances in sympathetic preganglionic neurons.	Potassium	62-71	adrenoceptor alpha 1D	Homo sapiens	22-41
12106302-0	1992	Reduction of Potassium Conductances Mediated by Metabotropic Glutamate Receptors in Rat CA3 Pyramidal Cells Does Not Require Protein Kinase C or Protein Kinase A.	Potassium	13-22	carbonic anhydrase 3	Rattus norvegicus	88-91
1284139-8	1992	Other actions of insulin, such as the transport of ions, (e.g., sodium and potassium), synthesis of insulin-like growth factor-binding proteins, translocation of transporter proteins, and regulation of enzyme activities, are much more difficult to quantify.	Potassium	75-84	insulin	Homo sapiens	17-24
1305067-8	1992	28 nmol/L TRH markedly increased vasopressin release but inhibited that of oxytocin from the neurointermediate lobes incubated in vitro both under basal conditions as well as during stimulation with excess (56 mmol) potassium.	Potassium	216-225	thyrotropin releasing hormone	Rattus norvegicus	10-13
1382167-7	1992	In further studies, angiotensin II (Ang II) was shown to decrease potassium-stimulated [3H] acetylcholine release from slices of rat entorhinal and human temporal cortex, an effect that could be antagonized by the angiotensin receptor antagonist [1-sar,8-thr]Ang II.	Potassium	66-75	angiotensinogen	Rattus norvegicus	20-34
1382167-7	1992	In further studies, angiotensin II (Ang II) was shown to decrease potassium-stimulated [3H] acetylcholine release from slices of rat entorhinal and human temporal cortex, an effect that could be antagonized by the angiotensin receptor antagonist [1-sar,8-thr]Ang II.	Potassium	66-75	angiotensinogen	Rattus norvegicus	36-42
1382167-7	1992	In further studies, angiotensin II (Ang II) was shown to decrease potassium-stimulated [3H] acetylcholine release from slices of rat entorhinal and human temporal cortex, an effect that could be antagonized by the angiotensin receptor antagonist [1-sar,8-thr]Ang II.	Potassium	66-75	angiotensinogen	Rattus norvegicus	259-265
1477029-6	1992	This finding suggests that osmotic mechanisms with various degree of well known abnormal insulin secretion and resistance to insulin action in target tissues in NIDDM patients may account for these heterogeneous responses in serum potassium changes after glucose load, and normal aldosterone levels may not be sufficient to prevent glucose induced increases in serum potassium in NIDDM patients.	Potassium	231-240	insulin	Homo sapiens	89-96
1522756-3	1992	The latency to obtain a 50% decrease in the amplitude of the CA1 population spike (CA1 PS) during a short- (5-10 min) lasting hypoxic period was significantly increased (P less than 0.01) by slice perfusion with caffeine (50 microM), DPCPX (0.2 microM), and by increasing (from 3 to 4 mM) the potassium concentration in the medium bathing the hippocampal slices.	Potassium	293-302	carbonic anhydrase 1	Rattus norvegicus	61-64
1522756-3	1992	The latency to obtain a 50% decrease in the amplitude of the CA1 population spike (CA1 PS) during a short- (5-10 min) lasting hypoxic period was significantly increased (P less than 0.01) by slice perfusion with caffeine (50 microM), DPCPX (0.2 microM), and by increasing (from 3 to 4 mM) the potassium concentration in the medium bathing the hippocampal slices.	Potassium	293-302	carbonic anhydrase 1	Rattus norvegicus	83-86
1329268-2	1992	Both AII and AVP specifically induce a transient increases in cytosolic free calcium independent of extracellular calcium or calcium channels activated by high potassium depolarization in VSM cells loaded with Fura-2.	Potassium	160-169	arginine vasopressin	Rattus norvegicus	13-16
1351266-10	1992	In contrast, dendritic gradients of Ca2+ induced by short exposures to high potassium (50 mM, 5 s) collapsed immediately at the end of the stimulus and could be repeatedly evoked.	Potassium	76-85	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	36-39
1793613-0	1991	Impaired insulin mediated potassium uptake in adolescents with IDDM.	Potassium	26-35	insulin	Homo sapiens	9-16
1320267-2	1992	Cellular depletion in potassium inhibits the internalization of VIP (23%) and to a greater extent (42%) that of Tf.	Potassium	22-31	vasoactive intestinal peptide	Homo sapiens	64-67
1320267-2	1992	Cellular depletion in potassium inhibits the internalization of VIP (23%) and to a greater extent (42%) that of Tf.	Potassium	22-31	transferrin	Homo sapiens	112-114
1750567-4	1991	We reported previously that inhibiting the Na-K-ATPase with ouabain or salt solutions lacking potassium evokes phase shifts with the same phase dependence as those induced by pulses of darkness.	Potassium	94-103	ATPase Na+/K+ transporting subunit alpha 1	Gallus gallus	43-54
1793613-3	1991	Insulin-mediated decrease in serum potassium (K+) and in blood urea nitrogen (BUN) concentration was evaluated in 20 adolescents with IDDM and 10 matched controls during a 3-h hyperinsulinemic (1.7 mU/kg/min)-euglycemic clamp study.	Potassium	35-44	insulin	Homo sapiens	0-7
1757462-5	1991	Moreover, depletion of intracellular potassium, which has been shown to disrupt coated pit formation, inhibited the rapid internalization of [125I]insulin at physiological insulin concentrations by CHO/IR cells, but had little or no effect on [125I]insulin uptake by CHO/IR delta 960 and CHO/IRA1018 cells or wild-type cells at high insulin concentrations.	Potassium	37-46	insulin	Cricetulus griseus	147-154
1757462-5	1991	Moreover, depletion of intracellular potassium, which has been shown to disrupt coated pit formation, inhibited the rapid internalization of [125I]insulin at physiological insulin concentrations by CHO/IR cells, but had little or no effect on [125I]insulin uptake by CHO/IR delta 960 and CHO/IRA1018 cells or wild-type cells at high insulin concentrations.	Potassium	37-46	insulin	Cricetulus griseus	172-179
1757462-5	1991	Moreover, depletion of intracellular potassium, which has been shown to disrupt coated pit formation, inhibited the rapid internalization of [125I]insulin at physiological insulin concentrations by CHO/IR cells, but had little or no effect on [125I]insulin uptake by CHO/IR delta 960 and CHO/IRA1018 cells or wild-type cells at high insulin concentrations.	Potassium	37-46	insulin	Cricetulus griseus	172-179
1757462-5	1991	Moreover, depletion of intracellular potassium, which has been shown to disrupt coated pit formation, inhibited the rapid internalization of [125I]insulin at physiological insulin concentrations by CHO/IR cells, but had little or no effect on [125I]insulin uptake by CHO/IR delta 960 and CHO/IRA1018 cells or wild-type cells at high insulin concentrations.	Potassium	37-46	insulin	Cricetulus griseus	172-179
1792002-0	1991	5-Hydroxytryptamine hyperpolarizes CA3 hippocampal pyramidal cells through an increase in potassium conductance.	Potassium	90-99	carbonic anhydrase 3	Homo sapiens	35-38
1724782-0	1991	[Expression of keratin 16 in normal and lesional skin of solitary and multiple Bowen"s disease using monoclonal antibody Ks 8.12 staining].	Potassium	121-123	keratin 16	Homo sapiens	15-25
1724782-4	1991	Ks 8.12 may be regarded as a specific antibody for Keratin 16 in the skin and is used as a marker for hyperproliferation.	Potassium	0-2	keratin 16	Homo sapiens	51-61
1835657-5	1991	Second, we measured the kinetics of 45Ca2+ dissociation from phosphorylated ATPase in a "chase" experiment, by isotopic dilution of calcium under turnover conditions in the presence of potassium.	Potassium	185-194	dynein axonemal heavy chain 8	Homo sapiens	76-82
1792002-7	1991	Based on these results we conclude that the mechanism of action of the 5-HT inhibition of CA3 hippocampal pyramidal cell excitability is due to an increase in potassium conductance.	Potassium	159-168	carbonic anhydrase 3	Homo sapiens	90-93
1722940-2	1991	Resiniferatoxin, capsaicin, calcitonin gene-related peptide and neurokinin A all evoked a sustained, concentration-dependent vasodilatation of potassium (60 mM)-precontracted arteries.	Potassium	143-152	tachykinin precursor 1	Homo sapiens	64-76
1660260-4	1991	The decrease in the effect of vasopressin may have been caused by development of hypokalemia and hypercalcemia in the cosmonauts, and decrease in cellular potassium in the outer renal medulla (this effect was observed in experiments on rats after flights on biosatellites).	Potassium	155-164	arginine vasopressin	Rattus norvegicus	30-41
1663105-4	1991	The possibility that the Isk protein is involved in potassium permeation in the luminal membrane of the marginal cell will be also discussed.	Potassium	52-61	potassium voltage-gated channel subfamily E regulatory subunit 1	Rattus norvegicus	25-28
1768353-1	1991	For several years now, it has been known that the administering of adrenergic beta antagonists, especially of the beta-2 type, induce hypokalemia as a result of the entering of potassium into the skeletal muscle cells.	Potassium	177-186	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	114-120
1935303-2	1991	The control mean serum potassium concentration of 3.65 mEq/L was decreased to 2.14 mEq/L by insulin and furosemide administration.	Potassium	23-32	insulin	Canis lupus familiaris	92-99
1683643-2	1991	In this study multipoint linkage analysis of two Duffy-linked families given a combined LOD score of 8.65 to establish that the Duffy-linked CMT1B gene exists in the 18 centimorgan region between the antithrombin III gene and the Duffy/sodium-potassium ATPase loci.	Potassium	243-252	myelin protein zero	Homo sapiens	141-146
1822542-0	1991	A potassium current evoked by growth hormone-releasing hormone in follicular oocytes of Xenopus laevis.	Potassium	2-11	growth hormone releasing hormone L homeolog	Xenopus laevis	30-62
1683643-2	1991	In this study multipoint linkage analysis of two Duffy-linked families given a combined LOD score of 8.65 to establish that the Duffy-linked CMT1B gene exists in the 18 centimorgan region between the antithrombin III gene and the Duffy/sodium-potassium ATPase loci.	Potassium	243-252	serpin family C member 1	Homo sapiens	200-216
1762664-1	1991	Cholecystokinin (CCK) affects neuronal excitability in a variety of in vivo and in vitro preparations, apparently by modulating a resting potassium conductance.	Potassium	138-147	cholecystokinin	Rattus norvegicus	17-20
1941619-3	1991	Release of AVP from isolated intact neurohypophyses, induced by either electrical stimulation or elevated potassium, was inhibited by clinically relevant concentrations of EtOH.	Potassium	106-115	arginine vasopressin	Rattus norvegicus	11-14
1762664-2	1991	The data presented here show that CCK (applied as CCK8-S) also affects the transient potassium current in hippocampal neurones, by changing the voltage dependence of the inactivation and activation of the current.	Potassium	85-94	cholecystokinin	Rattus norvegicus	34-37
1665913-0	1991	Chlorophyll photosensitized electron transfer reactions in lipid vesicles: enhancement in yield of vectorial electron transfer across the bilayer from reduced cytochrome c to oxidized ferredoxin by addition of valinomycin plus potassium ion.	Potassium	227-236	cytochrome c, somatic	Homo sapiens	159-171
1936189-9	1991	We have also analysed the evoked release of endogenous NPY from frog retina, induced either with light flashes (3 Hz, 300 lx), or with potassium depolarization of the neurons (40 mM).	Potassium	135-144	neuropeptide Y	Oryctolagus cuniculus	55-58
1928061-5	1991	Insulin is well positioned to play an important role in the regulation of plasma potassium concentration in patients with impaired renal function.	Potassium	81-90	insulin	Homo sapiens	0-7
1928061-7	1991	Furthermore, stimulation of endogenous insulin by oral glucose results in a greater intracellular translocation of potassium in uremic rats than in controls.	Potassium	115-124	insulin	Homo sapiens	39-46
1928061-9	1991	However, it is important to appreciate that the response to beta 2-adrenoreceptor-mediated internal potassium disposal is heterogeneous as judged by the variable responses to epinephrine infusion.	Potassium	100-109	adrenoceptor beta 2	Homo sapiens	60-81
1804283-5	1991	After the trial period, urinary kallikrein in the active group increased from 0.9 +/- 0.4 U/24 h (normal value greater than 1.2 U/24 h) to 1.6 +/- 1 U/24 h (p less than 0.05); systolic and diastolic blood pressure decreased respectively from 154.6 +/- 13.8 mmHg to 140.3 +/- 12.5 mmHg (p less than 0.01) and from 92.5 +/- 1.5 mmHg to 86 +/- 3.9 mmHg (p less than 0.025); urinary sodium and potassium excretion increased respectively from 96.7 +/- 17 mEq/24 h to 119.1 +/- 32.3 mEq/24 h (p less than 0.05) and from 36.7 +/- 11 mEq/24 h to 43.5 +/- 12.8 mEq/24 h (p less than 0.05).	Potassium	390-399	kallikrein related peptidase 4	Homo sapiens	32-42
1936189-10	1991	Light flashes and potassium induced an increased release of NPY-LI of 61 and 77%, respectively.	Potassium	18-27	neuropeptide Y	Oryctolagus cuniculus	60-63
1749518-1	1991	In the rat hippocampal slice, we evaluated the effects of potassium depolarization on phosphorylation of the alpha subunit of the pyruvate dehydrogenase complex (E1 alpha, mol.	Potassium	58-67	branched chain keto acid dehydrogenase E1 subunit alpha	Rattus norvegicus	162-170
1681489-3	1991	Somatostatin decreases the renal plasma flow, glomerular filtration rate, osmotic and free water clearances, sodium and potassium excretion and the tubular reabsorption of phosphorus while urinary osmolality increases.	Potassium	120-129	somatostatin	Homo sapiens	0-12
1660969-5	1991	These results implicate a neuronal contribution to the regulation of connexin43 expression by astrocytes and, hence, to local control of the potassium spatial buffering capacity afforded by astrocyte gap junctions.	Potassium	141-150	gap junction protein, alpha 1	Rattus norvegicus	69-79
1787642-2	1991	This has been attributed to excess PTH since extrarenal disposition of potassium is normal in CRF-PTX animals.	Potassium	71-80	parathyroid hormone	Rattus norvegicus	35-38
1686201-12	1991	The calcium current entering motor nerve terminals, revealed after blocking presynaptic potassium currents with tetraethylammonium (10 mM) in the presence of elevated extracellular Ca2+ (8 mM), was markedly reduced by Gd3+ (0.2-0.5 mM).	Potassium	88-97	GRDX	Homo sapiens	218-221
1874934-0	1991	Insulin effects on glucose and potassium metabolism in vivo: evidence for selective insulin resistance in humans.	Potassium	31-40	insulin	Homo sapiens	0-7
1874934-1	1991	UNLABELLED: The effects of insulin on in vivo glucose use and potassium uptake in healthy humans are well documented.	Potassium	62-71	insulin	Homo sapiens	27-34
1874934-9	1991	These results indicate that: 1) patients with AN are resistant to insulin action on glucose use, 2) AN patients have a normal response to insulin on potassium uptake, 3) HK is a patient with normal response to insulin on glucose use, and 4) this patient is resistant to insulin action on potassium uptake.	Potassium	149-158	insulin	Homo sapiens	138-145
1874934-9	1991	These results indicate that: 1) patients with AN are resistant to insulin action on glucose use, 2) AN patients have a normal response to insulin on potassium uptake, 3) HK is a patient with normal response to insulin on glucose use, and 4) this patient is resistant to insulin action on potassium uptake.	Potassium	149-158	insulin	Homo sapiens	138-145
1874934-9	1991	These results indicate that: 1) patients with AN are resistant to insulin action on glucose use, 2) AN patients have a normal response to insulin on potassium uptake, 3) HK is a patient with normal response to insulin on glucose use, and 4) this patient is resistant to insulin action on potassium uptake.	Potassium	149-158	insulin	Homo sapiens	138-145
1874934-10	1991	IN CONCLUSION: 1) we have demonstrated the independence of insulin action on glucose and potassium uptake in vivo, 2) we documented the existence of selective insulin resistance in the above patients, 3) we speculate, that in patients with a normal response to insulin on one parameter of its actions, and subnormal response on another parameter, a postreceptor defect rather than a receptor abnormality must exist.	Potassium	89-98	insulin	Homo sapiens	59-66
1681847-0	1991	Effects of selective beta 2-adrenoceptor blockade on serum potassium and exercise performance in normal men.	Potassium	59-68	adrenoceptor beta 2	Homo sapiens	21-40
1759371-0	1991	[The effect of naphthalan on the fast potassium current of pond snail neurons].	Potassium	38-47	snail family transcriptional repressor 1	Homo sapiens	64-69
1893645-3	1991	The benefits of ACE inhibition include not only a reduction in blood pressure but also improved insulin responsiveness, prevention of potassium loss, diminished myocardial oxygen demand, suppression of catecholamines, and interaction with bradykinin and prostaglandins.	Potassium	134-143	angiotensin I converting enzyme	Homo sapiens	16-19
1861625-0	1991	Evidence that potassium deficiency induces growth retardation through reduced circulating levels of growth hormone and insulin-like growth factor I.	Potassium	14-23	gonadotropin releasing hormone receptor	Rattus norvegicus	100-114
1855477-5	1991	In response to higher potassium concentrations in the medium (9 vs. 3.6 mM K+), adrenal capsules and dispersed glomerulosa cells both released significantly more AI and AII into the superfusate.	Potassium	22-31	angiotensinogen	Rattus norvegicus	169-172
2065906-6	1991	Neuropeptide Y significantly increased net absorption of water, sodium, potassium, and chloride under basal conditions.	Potassium	72-81	neuropeptide Y	Homo sapiens	0-14
1861625-0	1991	Evidence that potassium deficiency induces growth retardation through reduced circulating levels of growth hormone and insulin-like growth factor I.	Potassium	14-23	insulin-like growth factor 1	Rattus norvegicus	119-147
1925970-0	1991	Calcitonin gene-related peptide in the amygdaloid complex of the rat: immunohistochemical and quantitative distribution, and drug effects on calcium dependent, potassium-evoked in vitro release.	Potassium	160-169	calcitonin-related polypeptide alpha	Rattus norvegicus	0-10
1787876-5	1991	In contrast, increasing the endogenous acetylcholine in the preparation by inhibiting acetylcholinesterase resulted in a 1.2 to 12 fold increase in dopamine release depending upon the incubation time and the potassium concentration.	Potassium	208-217	acetylcholinesterase	Rattus norvegicus	86-106
1925970-7	1991	High potassium (60 mM) caused a significant release of calcitonin gene-related peptidelike immunoreactivity (from 0.88% of total tissue content to 1.91%) from the amygdaloid complex in vitro, which was blocked in calcium-free buffer.	Potassium	5-14	calcitonin-related polypeptide alpha	Rattus norvegicus	55-65
1680616-0	1991	Effects of adrenergic blockade on serum potassium changes in response to acute insulin-induced hypoglycemia in nondiabetic humans.	Potassium	40-49	insulin	Homo sapiens	79-86
1680616-1	1991	OBJECTIVE: To determine the possible role of adrenergic mechanisms in mediating the fall in serum potassium concentration after intravenous injection of insulin.	Potassium	98-107	insulin	Homo sapiens	153-160
1646711-1	1991	Secretin is a 27 amino acid peptide which stimulates the secretion of bicarbonate, enzymes and potassium ion from the pancreas.	Potassium	95-104	secretin	Rattus norvegicus	0-8
1647306-10	1991	In cells pretreated with angiotensin-II or 15 mM potassium, the intracellular calcium response to PTH was markedly potentiated.	Potassium	49-58	parathyroid hormone	Bos taurus	98-101
1715087-9	1991	In contrast, NPY (10(-6) M) produced significant inhibition of amylase release from pancreatic lobules that had been stimulated by 75 mM potassium (135 +/- 11% versus 177 +/- 18% of basal level) or by 25 microM veratridine (196 +/- 19% versus 398 +/- 152%).	Potassium	137-146	neuropeptide Y	Rattus norvegicus	13-16
1870424-5	1991	At any given insulin level, the obese individuals excreted significantly more calcium, phosphate, and potassium per minute than lean controls.	Potassium	102-111	insulin	Homo sapiens	13-20
1832749-4	1991	The icv administration of the h-ANP antiserum significantly increased the spontaneous water intake, urine output and urinary potassium excretion in rats given water ad libitum.	Potassium	125-134	natriuretic peptide A	Rattus norvegicus	32-35
1646611-0	1991	Augmentation of vasopressin-induced cAMP production by high potassium in rat renal papillary collecting tubule cells in culture.	Potassium	60-69	arginine vasopressin	Rattus norvegicus	16-27
1646611-1	1991	The effect of high potassium, 60 mM KCl, on the cellular action of arginine vasopressin (AVP) was studied in rat renal papillary collecting tubule cells in culture.	Potassium	19-28	arginine vasopressin	Rattus norvegicus	76-87
2047864-1	1991	Voltage-clamp analysis of Drosophila larval muscle revealed that ether a go-go (eag) mutations affected all identified potassium currents, including those specifically eliminated by mutations in the Shaker or slowpoke gene.	Potassium	119-128	ether a go-go	Drosophila melanogaster	65-78
2047864-1	1991	Voltage-clamp analysis of Drosophila larval muscle revealed that ether a go-go (eag) mutations affected all identified potassium currents, including those specifically eliminated by mutations in the Shaker or slowpoke gene.	Potassium	119-128	ether a go-go	Drosophila melanogaster	80-83
2038329-5	1991	However, PR and glucocorticoid receptor, but not ER, are able to contact the 5"-methyl group of thymines found in position 3 of HREs, as shown by potassium permanganate interference.	Potassium	146-155	progesterone receptor	Homo sapiens	9-11
12106484-3	1991	We now report that MCDP, at nanomolar concentrations, induces a reduction of a transient voltage-dependent potassium current (ID) in CA3 rat pyramidal neurons and a persistent (>30 min) enhancement of the frequency of spontaneous miniature excitatory and inhibitory postsynaptic currents (m.e.p.s.c.s.	Potassium	107-116	carbonic anhydrase 3	Rattus norvegicus	133-136
1904963-5	1991	NPY significantly inhibited ACh release stimulated by potassium (55 mM); by adenylate cyclase agonists forskolin (10(-6) M) and cholera toxin (10(-8) M); and by calcitonin gene-related peptide, cholecystokinin octapeptide, and vasoactive intestinal peptide (each 10(-8) M).	Potassium	54-63	pro-neuropeptide Y	Cavia porcellus	0-3
2035634-0	1991	ANG II blocks potassium currents in zona glomerulosa cells from rat, bovine, and human adrenals.	Potassium	14-23	angiotensinogen	Rattus norvegicus	0-6
2019269-5	1991	The positive interaction between Tg and potassium on aldosterone production raises the possibility that stimuli generating Ca2+ signal by depleting intracellular Ca2+ stores, such as Tg or AII, enhance the response of the cell to depolarization.	Potassium	40-49	angiotensinogen	Rattus norvegicus	189-192
1673969-8	1991	Furthermore, after perturbation of clathrin-dependent endocytosis by potassium depletion where uptake of transferrin is blocked, noncoated endocytic vesicles with Con A-gold, but not coated vesicles, exist already after 30 and 60 s. Finally, it is shown that the existence of small, free vesicles in the short-time experiments cannot be ascribed to recycling from the early endosomes.	Potassium	69-78	transferrin	Homo sapiens	105-116
1649984-0	1991	The naphthalenesulphonamide calmodulin antagonist W7 and its 5-iodo-1-C8 analogue inhibit potassium and calcium currents in NG108-15 neuroblastoma x glioma cells in a manner possibly unrelated to their antagonism of calmodulin.	Potassium	90-99	calmodulin 2	Mus musculus	28-38
1707674-1	1991	Previous studies have demonstrated that bradykinin hyperpolarizes the cell membrane of subconfluent MDCK cells by increase of the potassium conductance.	Potassium	130-139	kininogen 1	Canis lupus familiaris	40-50
2029728-16	1991	Our results show that chronic sodium, chloride, or potassium depletion differentially affect brain vasopressin mRNA and vasopressin release in young rats.	Potassium	51-60	arginine vasopressin	Rattus norvegicus	120-131
1707674-9	1991	Furthermore, bradykinin is able to transiently enhance the potassium conductance without a general increase of intracellular calcium.	Potassium	59-68	kininogen 1	Canis lupus familiaris	13-23
2029728-2	1991	We studied the effects of selective chronic dietary sodium, chloride, or potassium depletion in young rats on vasopressin mRNA levels in the supraoptic and paraventricular nuclei, an index of vasopressin formation, and in plasma vasopressin levels, an index of vasopressin release.	Potassium	73-82	arginine vasopressin	Rattus norvegicus	110-121
2072372-0	1991	Potassium supplementation lowers blood pressure and increases urinary kallikrein in essential hypertensives.	Potassium	0-9	kallikrein related peptidase 4	Homo sapiens	70-80
2029728-10	1991	After 2 weeks of potassium depletion, vasopressin mRNA levels were decreased in the supraoptic nucleus.	Potassium	17-26	arginine vasopressin	Rattus norvegicus	38-49
2029728-11	1991	When potassium depletion was prolonged for 3 weeks, vasopressin mRNA levels increased in both supraoptic and paraventricular nuclei.	Potassium	5-14	arginine vasopressin	Rattus norvegicus	52-63
2029728-13	1991	Plasma vasopressin levels were high in animals subjected to dietary chloride depletion or to 3 weeks of potassium depletion.	Potassium	104-113	arginine vasopressin	Rattus norvegicus	7-18
2029728-16	1991	Our results show that chronic sodium, chloride, or potassium depletion differentially affect brain vasopressin mRNA and vasopressin release in young rats.	Potassium	51-60	arginine vasopressin	Rattus norvegicus	99-110
1900783-5	1991	During first phase action TRH was found to increase calcium-dependent potassium current.	Potassium	70-79	thyrotropin releasing hormone	Rattus norvegicus	26-29
1900783-11	1991	These results indicate that the second phase action of TRH on action potential behavior in GH3 cells is mediated by a reduction in L-type calcium current and alterations in the behavior of calcium-dependent potassium currents, but not through changes in voltage-dependent potassium currents.	Potassium	207-216	thyrotropin releasing hormone	Rattus norvegicus	55-58
1900783-11	1991	These results indicate that the second phase action of TRH on action potential behavior in GH3 cells is mediated by a reduction in L-type calcium current and alterations in the behavior of calcium-dependent potassium currents, but not through changes in voltage-dependent potassium currents.	Potassium	272-281	thyrotropin releasing hormone	Rattus norvegicus	55-58
1849283-12	1991	The high potassium-induced release of ACTH, TSH, and GH was not affected.	Potassium	9-18	proopiomelanocortin	Homo sapiens	38-42
1849283-12	1991	The high potassium-induced release of ACTH, TSH, and GH was not affected.	Potassium	9-18	growth hormone 1	Homo sapiens	53-55
1850248-6	1991	The transformation of corticosterone under angiotensin II stimulation yielded up to 41% of 18-hydroxycorticosterone (4.7 micrograms/mg of cell protein per 24h) and 4.4% of aldosterone (0.5 microgram/mg of cell protein per 24h) in a low potassium concentration medium (6 mmol/l).	Potassium	236-245	angiotensinogen	Rattus norvegicus	43-57
1828306-1	1991	The circadian variation of plasma atrial natriuretic peptide (ANP) in relation to urinary excretion of sodium (UNa) and potassium (UK) as well as clearance of creatinine (Ccrea) was assessed in 15 juvenile patients with enuresis nocturna and compared with 11 age-, sex-, and weight-matched normal subjects.	Potassium	120-129	natriuretic peptide A	Homo sapiens	34-60
1828306-1	1991	The circadian variation of plasma atrial natriuretic peptide (ANP) in relation to urinary excretion of sodium (UNa) and potassium (UK) as well as clearance of creatinine (Ccrea) was assessed in 15 juvenile patients with enuresis nocturna and compared with 11 age-, sex-, and weight-matched normal subjects.	Potassium	120-129	natriuretic peptide A	Homo sapiens	62-65
1828306-8	1991	In conclusion, the study describes the diurnal variation of plasma ANP in relation to urinary excretion of sodium and potassium in a juvenile normal population.	Potassium	118-127	natriuretic peptide A	Homo sapiens	67-70
1905577-6	1991	Biochemical features revealed by high potassium stimulation may be an expression of "delayed neuronal death" in the hippocampal CA1 area.	Potassium	38-47	carbonic anhydrase 1	Rattus norvegicus	128-131
2009938-5	1991	In contrast, in six dogs whose plasma potassium concentration increased in each case by more than 2.0 mEq/l (infusion rate of 0.5 mEq/kg/h), portal insulin levels increased fivefold (p less than 0.05).	Potassium	38-47	insulin	Canis lupus familiaris	148-155
1999174-0	1991	Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: evidence for a sequential block of receptor--mediated endocytosis.	Potassium	66-75	growth hormone receptor	Homo sapiens	89-112
1707713-8	1991	Exposure to potassium also released CGRP-LI in a Ca2(+)-dependent fashion from the LAD.	Potassium	12-21	calcitonin related polypeptide alpha	Homo sapiens	36-40
1705122-1	1991	Endothelin-1 (ET-1) stimulated release of both noradrenaline and adrenaline from cultured bovine adrenal chromaffin cells; stimulated release was small compared to that elicited by 50 mM potassium.	Potassium	187-196	endothelin 1	Bos taurus	0-12
1671657-4	1991	Voltage clamp records of isolated currents indicate that TRH affects calcium-dependent potassium currents, but does not alter either voltage-dependent potassium or calcium currents at times and concentrations at which the electrical activity is increased.	Potassium	87-96	thyrotropin releasing hormone	Rattus norvegicus	57-60
1826998-6	1991	In contrast, plasma insulin response was negatively correlated with erythrocyte potassium concentration (r = 0.40, P less than 0.05).	Potassium	80-89	insulin	Homo sapiens	20-27
1707713-10	1991	In functional experiments on human epicardial coronary arteries with an inner diameter of 0.4 to 0.8 mm, human CGRP alpha and beta relaxed the potassium-precontracted arteries equipotently.	Potassium	143-152	calcitonin related polypeptide alpha	Homo sapiens	111-115
1996669-10	1991	These experiments demonstrate that acute hyperkalemia can cause renal vasodilation and stimulate renin release in both filtering and nonfiltering kidney preparations and that potassium may affect renin release both through a direct effect on the juxtaglomerular cells and indirectly by affecting delivery of fluid and/or NaCl to the macula densa.	Potassium	175-184	renin	Homo sapiens	196-201
1707713-17	1991	It is concluded that CGRP-LI is present in human cardiopulmonary tissue and can be released upon exposure to high concentrations of capsaicin as well as potassium.	Potassium	153-162	calcitonin related polypeptide alpha	Homo sapiens	21-25
1991649-9	1991	Insulin had no effect on oxygen consumption, carbon dioxide production, and respiratory quotient in either study group, whereas it stimulated free fatty acids, glycerol, and potassium uptake to the same extent in the hypertensive and normotensive groups.	Potassium	174-183	insulin	Homo sapiens	0-7
1988777-0	1991	Sodium retention by insulin may depend on decreased plasma potassium.	Potassium	59-68	insulin	Homo sapiens	20-27
1988777-5	1991	Without potassium infusion, insulin caused a marked decrease in plasma potassium (-0.75 mmol/L), and decreased urinary sodium and potassium excretions by, approximately 38% and 65%, respectively.	Potassium	71-80	insulin	Homo sapiens	28-35
1988777-5	1991	Without potassium infusion, insulin caused a marked decrease in plasma potassium (-0.75 mmol/L), and decreased urinary sodium and potassium excretions by, approximately 38% and 65%, respectively.	Potassium	71-80	insulin	Homo sapiens	28-35
1993123-1	1991	Opioid receptors were found to activate two different types of membrane potassium conductance in acutely dissociated neurons from the CA1/subiculum regions of the adult rat hippocampal formation.	Potassium	72-81	carbonic anhydrase 1	Rattus norvegicus	134-137
1711661-0	1991	Galanin increases potassium evoked release of [3H]5-hydroxytryptamine from rat hypothalamic synaptosomal preparations.	Potassium	18-27	galanin and GMAP prepropeptide	Rattus norvegicus	0-7
2020833-6	1991	The granulocyte potassium content was (median (range)) 37.4 (25.8-75.0) fmol/cell-1 or 2.9 (1.5-9.8) mmol g-1 DNA.	Potassium	16-25	carboxyl ester lipase pseudogene	Homo sapiens	77-90
2020833-7	1991	The lymphocyte potassium content was 45.9 (26.4-69.6) fmol cell-1 or 3.3 (1.5-5.0) mmol g-1 DNA.	Potassium	15-24	carboxyl ester lipase pseudogene	Homo sapiens	59-72
1985892-0	1991	Effect of potassium ions and membrane potential on the Na-Ca-K exchanger in isolated intact bovine rod outer segments.	Potassium	10-19	nascent polypeptide-associated complex subunit alpha	Bos taurus	55-60
1674473-6	1991	Current-voltage relations of the somatostatin-induced, PTX-resistant hyperpolarization indicated a reversal potential close to the equilibrium potential for potassium ions.	Potassium	157-166	somatostatin	Rattus norvegicus	33-45
1985892-7	1991	Potassium ions activated Na-Ca exchange when present on the Ca2+ side, although the extent of activation decreased with decreasing Na+ concentration.	Potassium	0-9	nascent polypeptide-associated complex subunit alpha	Bos taurus	25-30
1985892-8	1991	Potassium ions inhibited Na-Ca exchange when present on the Na+ side; inhibition arose from competition between Na+ and K+ for a common single cation-binding site.	Potassium	0-9	nascent polypeptide-associated complex subunit alpha	Bos taurus	25-30
1987779-0	1991	Regulation of calcium-activated potassium efflux by neurotensin and other agents in HT-29 cells.	Potassium	32-41	neurotensin	Homo sapiens	52-63
1657029-5	1991	The overexpression of the K-fgf gene in KS is not proven unequivocally; some doubts exist suggesting the activation of this gene during the laboratory procedure of transfection with KS cell heavy DNA.	Potassium	40-42	fibroblast growth factor 4	Homo sapiens	26-31
1660381-1	1991	In a patient with hypokalemic periodic paralysis (HPP), recovery from a paralytic attack, coinciding with the restoration of plasma potassium, was associated with a rise in serum myoglobin (Mb) and creatine kinase (CK).	Potassium	132-141	myoglobin	Homo sapiens	179-188
1657029-5	1991	The overexpression of the K-fgf gene in KS is not proven unequivocally; some doubts exist suggesting the activation of this gene during the laboratory procedure of transfection with KS cell heavy DNA.	Potassium	182-184	fibroblast growth factor 4	Homo sapiens	26-31
1657029-13	1991	We theorize that when TGF-beta production ceases, TNF-beta (lymphotoxin) production switches on leading to programmed cell death (apoptosis) of KS cells resulting in regression of these lesions.	Potassium	144-146	transforming growth factor beta 1	Homo sapiens	22-30
1657029-13	1991	We theorize that when TGF-beta production ceases, TNF-beta (lymphotoxin) production switches on leading to programmed cell death (apoptosis) of KS cells resulting in regression of these lesions.	Potassium	144-146	lymphotoxin alpha	Homo sapiens	50-58
12106200-4	1991	Activators of protein kinase C, such as phorbol esters or diacylglycerol, also induce changes in potassium currents that appear, both in magnitude and kinetics, to be similar to those induced by antibodies against N-CAM.	Potassium	97-106	neural cell adhesion molecule 1	Mus musculus	214-219
1868965-4	1991	Both oxytocin and 8-l-lysine-vasopressin dose-dependently relaxed almost completely contractions caused by histamine and potassium in guinea pigs.	Potassium	121-130	arginine vasopressin	Homo sapiens	29-40
1778241-3	1991	Incubation of neurointermediate lobes in a solution containing indomethacin resulted in an inhibition of VP and OT release both during resting conditions and during depolarization due to excess potassium.	Potassium	194-203	arginine vasopressin	Rattus norvegicus	105-107
1675877-3	1991	Nitrogen and potassium retention was induced in the growth hormone group compared with the placebo group (cumulative nitrogen balance 4.1 (+/- 1.1) g/m2 in the growth hormone group and -3.1 (+/- 1.8) g/m2 in the placebo group, p less than 0.01; cumulative potassium balance 80.8 (+/- 4.7) mmol/m2 in the growth hormone group and 43.1 (+/- 11.4) mmol/m2 in the placebo group, p less than 0.01).	Potassium	13-22	growth hormone 1	Homo sapiens	52-66
1899114-0	1991	Quinidine inhibits prolactin secretion induced by thyrotropin-releasing hormone, high medium potassium or hyposmolarity in GH4C1 cells.	Potassium	93-102	prolactin	Rattus norvegicus	19-28
1647342-0	1991	Effects of calcium and potassium extracellular ionic concentration changes on the hippocampal CA1 activity of purinergic drugs.	Potassium	23-32	carbonic anhydrase 1	Homo sapiens	94-97
1723120-10	1991	Angiotensin II may increase the sensitivity to sympathetic nervous system arousal but also promotes renal loss of potassium and magnesium.	Potassium	114-123	angiotensinogen	Homo sapiens	0-14
1679107-3	1991	Both doses (0.1 and 0.3 microgram/minutes/kg) of ANF administered produced a marked increase in urinary flow, sodium and potassium excretion in the SL rats.	Potassium	121-130	natriuretic peptide A	Rattus norvegicus	49-52
1823389-4	1991	The rise in urinary potassium excretion following furosemide administration was significantly lower in the presence of high insulin concentrations.	Potassium	20-29	insulin	Homo sapiens	124-131
1823389-5	1991	Although we observed a slight decrease in plasma potassium levels during the equilibration phase of the clamp required before the administration of furosemide, a significantly lower increase in potassium fractional excretion indicated a direct tubular effect of insulin.	Potassium	194-203	insulin	Homo sapiens	262-269
1775537-0	1991	The majority of potassium ions in muscle cells is adsorbed on beta- and gamma-carboxyl groups of myosin: potassium-ion-adsorbing carboxyl groups on myosin heads engage in cross-bridge formation during contraction.	Potassium	16-25	myosin heavy chain 14	Homo sapiens	97-103
1684641-3	1991	Suppression of insulin by somatostatin may have contributed to the hyperkalemia by impairing cellular potassium uptake.	Potassium	102-111	insulin	Homo sapiens	15-22
1684641-3	1991	Suppression of insulin by somatostatin may have contributed to the hyperkalemia by impairing cellular potassium uptake.	Potassium	102-111	somatostatin	Homo sapiens	26-38
1992446-4	1991	The low mitogenicity of EGF and TGF-alpha for KS cells is not based upon a reduced expression of EGF receptor mRNA and protein in KS cells.	Potassium	46-48	epidermal growth factor	Homo sapiens	24-27
1992446-4	1991	The low mitogenicity of EGF and TGF-alpha for KS cells is not based upon a reduced expression of EGF receptor mRNA and protein in KS cells.	Potassium	46-48	transforming growth factor alpha	Homo sapiens	32-41
1992446-5	1991	However, the binding of EGF to KS cells is about 50% lower than that to fibroblasts.	Potassium	31-33	epidermal growth factor	Homo sapiens	24-27
1992446-7	1991	In contrast, the low EGF binding seems to be an intrinsic feature of the EGF receptors of KS cells.	Potassium	90-92	epidermal growth factor	Homo sapiens	21-24
1992446-7	1991	In contrast, the low EGF binding seems to be an intrinsic feature of the EGF receptors of KS cells.	Potassium	90-92	epidermal growth factor	Homo sapiens	73-76
1775537-0	1991	The majority of potassium ions in muscle cells is adsorbed on beta- and gamma-carboxyl groups of myosin: potassium-ion-adsorbing carboxyl groups on myosin heads engage in cross-bridge formation during contraction.	Potassium	16-25	myosin heavy chain 14	Homo sapiens	148-154
1775537-0	1991	The majority of potassium ions in muscle cells is adsorbed on beta- and gamma-carboxyl groups of myosin: potassium-ion-adsorbing carboxyl groups on myosin heads engage in cross-bridge formation during contraction.	Potassium	105-114	myosin heavy chain 14	Homo sapiens	97-103
1775537-0	1991	The majority of potassium ions in muscle cells is adsorbed on beta- and gamma-carboxyl groups of myosin: potassium-ion-adsorbing carboxyl groups on myosin heads engage in cross-bridge formation during contraction.	Potassium	105-114	myosin heavy chain 14	Homo sapiens	148-154
1881995-4	1991	In perfusion fluid obtained from the lateral ventricle of animals treated 1 month with HAL a dose-dependent increase of ENK levels was observed, which was augmented by potassium ions.	Potassium	168-177	proenkephalin	Rattus norvegicus	120-123
1858208-7	1991	In the total group of examinees a significant direct relationship was established between the urinary kallikrein activity and summary sodium and potassium excretion as well as between the serum kallikrein activity and chlorine clearance.	Potassium	145-154	kallikrein related peptidase 4	Homo sapiens	102-112
2266124-9	1990	Bradykinin also increased the affinity of the cotransporter for bumetanide as indicated by a decrease in the Ki for potassium influx from 464 +/- 46 nM to 219 +/- 19 nM (p less than 0.005).	Potassium	116-125	kininogen 1	Homo sapiens	0-10
2174021-0	1990	Role of the adrenal renin-angiotensin system on adrenocorticotropic hormone- and potassium-stimulated aldosterone production by rat adrenal glomerulosa cells in monolayer culture.	Potassium	81-90	renin	Rattus norvegicus	20-25
2260673-9	1990	A Ca2(+)-activated potassium [K(Ca)] current was activated by application of methacholine (100 microM), or A23187 (1 microM), under conditions of low Ca2+ buffering capacity in the internal solution [0.3 mM ethylene glycol-bis(beta-aminoethyl ether)-N,N,N",N"-tetraacetic acid (EGTA)].	Potassium	19-28	carbonic anhydrase 2	Canis lupus familiaris	2-5
2260673-9	1990	A Ca2(+)-activated potassium [K(Ca)] current was activated by application of methacholine (100 microM), or A23187 (1 microM), under conditions of low Ca2+ buffering capacity in the internal solution [0.3 mM ethylene glycol-bis(beta-aminoethyl ether)-N,N,N",N"-tetraacetic acid (EGTA)].	Potassium	19-28	carbonic anhydrase 2	Canis lupus familiaris	150-153
1965943-3	1990	Scatchard analysis of MPTP-cytochrome P-450 binding suggested that MPTP binds to at least 2 species of cytochrome P-450--a high affinity binding species with an apparent spectral dissociation constant (Ks) of 372 microM and a low affinity species with Ks of 37.6 mM.	Potassium	202-204	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	103-119
1965943-3	1990	Scatchard analysis of MPTP-cytochrome P-450 binding suggested that MPTP binds to at least 2 species of cytochrome P-450--a high affinity binding species with an apparent spectral dissociation constant (Ks) of 372 microM and a low affinity species with Ks of 37.6 mM.	Potassium	252-254	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	103-119
1701127-4	1990	Potassium concentrations of 10 mM, adenylate cyclase activators (glucagon-like peptide-1 and forskolin), and a phosphodiesterase inhibitor (isobutylmethylxanthine) potentiated glucose-induced insulin secretion, but had little or no effect on insulin secretion in the absence of glucose.	Potassium	0-9	glucagon	Rattus norvegicus	65-88
2096199-3	1990	The sodium/creatinine ratio [r = 0.10 (P less than 0.001)] and sodium/potassium ratio [r = 0.11 (P less than 0.001)] were positively correlated with SBP.	Potassium	70-79	selenium binding protein 1	Homo sapiens	149-152
2124245-4	1990	A multivariate analysis showed that localization of KS and CD4 count had independent predictive value, with an odds ratio of 35 for patients who had more than 300 CD4 cells at the onset of treatment versus those with less than 150.	Potassium	52-54	CD4 molecule	Homo sapiens	163-166
2258633-1	1990	Interferon alpha (IFN-alpha) has been shown to be effective in treating HIV-associated KS in at least 30% of patients, and Zidovudine has proved beneficial for AIDS patients.	Potassium	87-89	interferon alpha 1	Homo sapiens	0-27
2258633-3	1990	Based on the above, we combined IFN-alpha and zidovudine for treatment of HIV-associated KS in order to evaluate tolerance and clinical efficacy.	Potassium	89-91	interferon alpha 1	Homo sapiens	32-41
2170117-4	1990	After we had demonstrated that depolarization with high potassium (50 mM) resulted in an increase in the levels of both BDNF and NGF mRNAs in cultures of hippocampal neurons, we investigated the effect of a large number of transmitter substances.	Potassium	56-65	brain-derived neurotrophic factor	Rattus norvegicus	120-124
2282534-4	1990	CRH (10(-9)-10(-6) M) did not stimulate secretion of IR-beta-endorphin from hypothalamic cells which did release IR-beta-endorphin upon potassium-induced depolarization.	Potassium	136-145	proopiomelanocortin	Homo sapiens	116-130
1699751-5	1990	Furthermore, our data suggest that the form of ANP released from these cultures, following either forskolin treatment alone or forskolin treatment followed by acute high potassium depolarisation, was atriopeptin III (ANP5-28).	Potassium	170-179	natriuretic peptide A	Rattus norvegicus	47-50
2175372-2	1990	We found the existence of voltage activated inward and outward rectifying potassium currents, and the inhibition of the anomalous inward rectifying potassium current by Ang II.	Potassium	148-157	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	169-175
2223094-2	1990	A Xenopus nucleotide sequence (XSha2) encoding a potassium current has been isolated by homology screening with the Drosophila Shaker gene.	Potassium	49-58	potassium channel, voltage gated shaker related subfamily A, member 2 L homeolog	Xenopus laevis	31-36
2266671-2	1990	There was a similar decrease in plasma potassium following either insulin with glucose (0.65 +/- 0.09 mmol/liter) or albuterol (0.66 +/- 0.12 mmol/liter), and a substantially greater fall with the combined regimen (1.21 +/- 0.19 mmol/liter, P less than 0.02 vs. either drug alone).	Potassium	39-48	insulin	Homo sapiens	66-73
2266671-10	1990	These observations suggest that albuterol and insulin with glucose are equally efficacious in lowering plasma potassium in uremic patients, and that the hypokalemic effects of the two drugs is additive.	Potassium	110-119	insulin	Homo sapiens	46-53
2121533-4	1990	When stimulated with sulphonylurea, ionophore or high potassium, insulin was preferentially released into the lower chamber irrespective of whether secretagogues were added to the upper or lower chambers.	Potassium	54-63	insulin	Mesocricetus auratus	65-72
2223094-2	1990	A Xenopus nucleotide sequence (XSha2) encoding a potassium current has been isolated by homology screening with the Drosophila Shaker gene.	Potassium	49-58	Shaker	Drosophila melanogaster	127-133
2076204-9	1990	The kallikrein activity responded differently to pH, to metal ions (zinc and copper), and to the sodium/potassium ratio, depending on the concomitant presence or absence of UT-like material.	Potassium	104-113	kallikrein 1-related peptidase b9	Mus musculus	4-14
2149390-5	1990	Although other vasodilators have been shown to be anti-arrhythmic, ACE inhibitors also raise serum potassium levels and this may therefore be of importance to their anti-arrhythmic activity.	Potassium	99-108	angiotensin I converting enzyme	Homo sapiens	67-70
2257435-6	1990	Histamine caused a greater contraction for a given change in [Ca2+]i than did potassium, at [Ca2+]i over 300 nM.	Potassium	78-87	carbonic anhydrase 2	Homo sapiens	93-96
1717037-5	1990	In contrast, a significant inhibition of potassium-evoked, but not of basal NKA-IR and CGRP-IR release was observed when 10(-7) M BRL 43694 or ICS 205-930, two specific 5-HT3 receptor antagonists, were superfused together with 5-HT.	Potassium	41-50	5-hydroxytryptamine receptor 3A	Rattus norvegicus	169-183
2283639-2	1990	Major findings include a positive correlation between glucose/insulin ratio and serum potassium (P = 0.0014) and a weaker negative correlation between fasting insulin and serum potassium (P = 0.004).	Potassium	86-95	insulin	Homo sapiens	62-69
1981712-7	1990	The two isozymes had similar pH optima, similar KM values for the reaction co-substrates, 6-MP and S-adenosyl-L-methionine, and similar Ki and Ks values for the TPMT inhibitor 3,4-dimethoxy-5-hydroxybenzoic acid.	Potassium	143-145	thiopurine S-methyltransferase	Homo sapiens	161-165
2230914-0	1990	Model of synchronized epileptiform bursts induced by high potassium in CA3 region of rat hippocampal slice.	Potassium	58-67	carbonic anhydrase 3	Rattus norvegicus	71-74
2230914-3	1990	We constructed a computer model of the in vitro CA3 region of the rat hippocampal slice bathed in a high-potassium medium.	Potassium	105-114	carbonic anhydrase 3	Rattus norvegicus	48-51
1963337-6	1990	[Ca2+]i increase induced by high potassium depolarization was suppressed by bradykinin.	Potassium	33-42	kininogen 1	Homo sapiens	76-86
2292005-2	1990	Exposure to elevated extracellular potassium ions or 4-aminopyridine, but not picrotoxin, revealed an abnormally prolonged network discharge duration in the mutant CA3 pyramidal cell region.	Potassium	35-44	carbonic anhydrase 3	Mus musculus	164-167
2382142-5	1990	The EVF of CA1 stratum pyramidale was reversibly reduced by 30 percent when the extracellular potassium concentration was raised from 3.5 to 8.5 mM, a procedure that induced spontaneous electrographic seizures in CA1.	Potassium	94-103	carbonic anhydrase 1	Homo sapiens	11-14
2382142-5	1990	The EVF of CA1 stratum pyramidale was reversibly reduced by 30 percent when the extracellular potassium concentration was raised from 3.5 to 8.5 mM, a procedure that induced spontaneous electrographic seizures in CA1.	Potassium	94-103	carbonic anhydrase 1	Homo sapiens	213-216
2229022-6	1990	The heterogeneity of the ISK protein mRNAs may be associated with the emergence of the functional and regulatory diversity observed for potassium ion permeation in epithelial cells.	Potassium	136-145	potassium voltage-gated channel subfamily E regulatory subunit 1	Rattus norvegicus	25-28
1697379-1	1990	In the present studies we have shown that angiotensin II (AT II), in a concentration-dependent manner in rat tissue (10(-9)-10(-5) M) or at a single concentration in human tissue (10(-6) M), can inhibit potassium-stimulated release of [3H]acetylcholine ( [3H]Ach) from slices of rat entorhinal cortex and human temporal cortex preloaded with [3H]choline for the biochemical analyses.	Potassium	203-212	angiotensinogen	Rattus norvegicus	42-56
1697379-1	1990	In the present studies we have shown that angiotensin II (AT II), in a concentration-dependent manner in rat tissue (10(-9)-10(-5) M) or at a single concentration in human tissue (10(-6) M), can inhibit potassium-stimulated release of [3H]acetylcholine ( [3H]Ach) from slices of rat entorhinal cortex and human temporal cortex preloaded with [3H]choline for the biochemical analyses.	Potassium	203-212	angiotensinogen	Rattus norvegicus	58-63
2125700-12	1990	The potassium-stimulated, but not spontaneous, release of GnRH was lower in old than in young Ovx rats.	Potassium	4-13	gonadotropin releasing hormone 1	Rattus norvegicus	58-62
1695569-0	1990	Effects of high potassium concentration and dihydropyridine Ca2(+)-channel agonists on cytoplasmic Ca2+ and aldosterone production in rat adrenal glomerulosa cells.	Potassium	16-25	carbonic anhydrase 2	Rattus norvegicus	99-102
1695569-11	1990	These results indicate that the correlation between Ca2+ influx, cytoplasmic Ca2+ levels, and the secretory response in adrenal glomerulosa cells is lost at potassium concentrations higher than 8 mM, especially in the presence of the dihydropyridine agonist, BAY-K 8644.	Potassium	157-166	carbonic anhydrase 2	Rattus norvegicus	52-55
1695569-11	1990	These results indicate that the correlation between Ca2+ influx, cytoplasmic Ca2+ levels, and the secretory response in adrenal glomerulosa cells is lost at potassium concentrations higher than 8 mM, especially in the presence of the dihydropyridine agonist, BAY-K 8644.	Potassium	157-166	carbonic anhydrase 2	Rattus norvegicus	77-80
2125704-8	1990	Depolarisation of the MPOA by increasing the potassium ion concentration of the perfusion medium evoked significantly greater GABA release from OVX-EBp rats compared with the OVX and OVX-EBn animals.	Potassium	45-54	EBP, cholestenol delta-isomerase	Rattus norvegicus	148-151
2217901-5	1990	Release of 7B2 was also stimulated by potassium from 106% to 212% above basal values.	Potassium	38-47	secretogranin V	Rattus norvegicus	11-14
2371022-2	1990	The excitatory effect of oxytocin was enhanced by external magnesium, and the dose-response curve between oxytocin and relative tension in the presence of 118 mM potassium in tiny muscle strips shifted to the left with increases in magnesium from 0 to 2.4 mM.	Potassium	162-171	oxytocin/neurophysin I prepropeptide	Homo sapiens	25-33
2371022-2	1990	The excitatory effect of oxytocin was enhanced by external magnesium, and the dose-response curve between oxytocin and relative tension in the presence of 118 mM potassium in tiny muscle strips shifted to the left with increases in magnesium from 0 to 2.4 mM.	Potassium	162-171	oxytocin/neurophysin I prepropeptide	Homo sapiens	106-114
2371022-4	1990	In potassium contracture experiments, the muscle contraction was potentiated in accordance with the concentration of preloaded magnesium when 10(-3) U/mL oxytocin was added at the tonic phase.	Potassium	3-12	oxytocin/neurophysin I prepropeptide	Homo sapiens	154-162
2144189-6	1990	This is aggravated by the chemical similarity of the potassium and the ammonium ion, which leads to ammonium ion transport via the Kdp potassium transport system when the potassium concentration in the medium is low.	Potassium	53-62	WNK lysine deficient protein kinase 1	Homo sapiens	131-134
2144189-6	1990	This is aggravated by the chemical similarity of the potassium and the ammonium ion, which leads to ammonium ion transport via the Kdp potassium transport system when the potassium concentration in the medium is low.	Potassium	135-144	WNK lysine deficient protein kinase 1	Homo sapiens	131-134
2141574-7	1990	We mixed LN with the KS/CS-PG, where the LN was in concentrations which alone support outgrowth, and observed that the KS/CS-PG was still inhibitory when such a growth-promoting molecule was present.	Potassium	21-23	laminin, beta 2 (laminin S)	Gallus gallus	41-43
2397214-2	1990	Spermine, a polycation carrying a charge of 4 +, and potassium, a monovalent cation, were shown to differently cause an increase of high-spin content of camphor-bound cytochrome P-450.	Potassium	53-62	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	178-183
2397214-6	1990	Cytochrome P-420 was produced from cytochrome P-450 by hydrostatic pressure in the presence of potassium, spermine, and cysteine.	Potassium	95-104	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	46-51
2397214-7	1990	Potassium cation shows a bigger effect on the stability of cytochrome P-450 than spermine or cysteine, as revealed by a higher value of the pressure of half-inactivation, P1/2, and a bigger inactivation volume change.	Potassium	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	59-75
2171716-0	1990	Inhibition of potassium-evoked release of cholecystokinin from rat caudate-putamen, cerebral cortex and hippocampus incubated in vitro by phencyclidine and related compounds.	Potassium	14-23	cholecystokinin	Rattus norvegicus	42-57
2171716-1	1990	Potassium-evoked release of cholecystokinin (CCK) from slices of caudate-putamen, hippocampus, and cerebral cortex was inhibited in a dose-related fashion by phencyclidine (PCP).	Potassium	0-9	cholecystokinin	Rattus norvegicus	28-43
2171716-1	1990	Potassium-evoked release of cholecystokinin (CCK) from slices of caudate-putamen, hippocampus, and cerebral cortex was inhibited in a dose-related fashion by phencyclidine (PCP).	Potassium	0-9	cholecystokinin	Rattus norvegicus	45-48
2354450-10	1990	Continuous TNF infusion reduced total body nitrogen and potassium while pair feeding did not reduce potassium and reduced nitrogen to a lesser degree.	Potassium	56-65	tumor necrosis factor-like	Rattus norvegicus	11-14
2354450-12	1990	Twice a day administration of TNF resulted in lesser changes in carcass water, solid, nitrogen, lipid, and potassium than continuous infusion of the same dose of TNF.	Potassium	107-116	tumor necrosis factor-like	Rattus norvegicus	30-33
2394086-15	1990	This fact, in the presence of high levels of angiotensin II, induced a reduction of the glomerular filtration rate thus contributing to renal ability to retain chloride and potassium.	Potassium	173-182	angiotensinogen	Homo sapiens	45-59
2141574-7	1990	We mixed LN with the KS/CS-PG, where the LN was in concentrations which alone support outgrowth, and observed that the KS/CS-PG was still inhibitory when such a growth-promoting molecule was present.	Potassium	119-121	laminin, beta 2 (laminin S)	Gallus gallus	9-11
2141574-7	1990	We mixed LN with the KS/CS-PG, where the LN was in concentrations which alone support outgrowth, and observed that the KS/CS-PG was still inhibitory when such a growth-promoting molecule was present.	Potassium	119-121	laminin, beta 2 (laminin S)	Gallus gallus	41-43
2141574-8	1990	A 10-fold higher concentration of LN was able to overcome the inhibitory effect of the KS/CS-PG.	Potassium	87-89	laminin, beta 2 (laminin S)	Gallus gallus	34-36
2388254-0	1990	Bradykinin-induced potassium current in cultured bovine aortic endothelial cells.	Potassium	19-28	kininogen 1	Bos taurus	0-10
2229194-4	1990	In contrast, the potassium ionophore nonactin induces only a weak alteration in the hsp28 locale, while the calcium ionophore A23187 and the uncoupler of oxidative phosphorylation FCCP have no effect.	Potassium	17-26	heat shock protein family B (small) member 1	Homo sapiens	84-89
2381500-9	1990	That is, when AChE activity was intact, the potassium-stimulated choline release from slices of 28-month rats was less than that released from slices of 10-month rats when release was tested after a 1-hr incubation.	Potassium	44-53	acetylcholinesterase	Rattus norvegicus	14-18
16667575-0	1990	Potassium stimulation of corn root plasmalemma ATPase : I. Hydrolytic activity of native vesicles and purified enzyme.	Potassium	0-9	ATPase	Zea mays	47-53
2143001-1	1990	The effects of intraventricularly administered atrial natriuretic peptide (ANP) on the brain water, sodium, and potassium contents in ischemic brain edema were investigated.	Potassium	112-121	natriuretic peptide A	Rattus norvegicus	75-78
2206912-6	1990	For instance sodium depletion increases the expression of renal angiotensinogen (as well as renin mRNA), as does high potassium intake and androgen administration.	Potassium	118-127	angiotensinogen	Rattus norvegicus	64-79
2235293-4	1990	Contractions evoked by an increase extracellular potassium [( K+]0) produced a fall in pHi of 0.01-0.05 units.	Potassium	49-58	glucose-6-phosphate isomerase	Homo sapiens	87-90
16667576-0	1990	Potassium Stimulation of Corn Root Plasmalemma ATPase : II.	Potassium	0-9	ATPase	Zea mays	47-53
1698510-1	1990	The effect of potassium depolarization on dopamine D1 receptor activity in bovine retina was investigated.	Potassium	14-23	dopamine receptor D1	Bos taurus	42-62
1974461-1	1990	Both the chaperonin- and MgATP-dependent reconstitution of unfolded ribulosebisphosphate carboxylase (Rubisco) and the uncoupled ATPase activity of chaperonin 60 (groEL) require ionic potassium.	Potassium	184-193	heat shock protein family D (Hsp60) member 1	Homo sapiens	148-161
1974461-1	1990	Both the chaperonin- and MgATP-dependent reconstitution of unfolded ribulosebisphosphate carboxylase (Rubisco) and the uncoupled ATPase activity of chaperonin 60 (groEL) require ionic potassium.	Potassium	184-193	heat shock protein family D (Hsp60) member 1	Homo sapiens	163-168
2190930-7	1990	Possible mechanisms whereby insulin could increase angiotensin II-stimulated aldosterone production include: increased intracellular potassium, reduced plasma free fatty acids, and a direct action of insulin to induce increased adrenal steroidogenesis.	Potassium	133-142	insulin	Canis lupus familiaris	28-35
2351830-4	1990	RNA transcribed in vitro from RGK5 genomic DNA directs the expression of functional potassium currents after injection into Xenopus oocytes.	Potassium	84-93	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	30-34
2199313-1	1990	Saccharomyces cerevisiae cells containing a deletion of TRK1, the gene encoding the high affinity potassium transporter, retain only low affinity uptake of this ion and consequently lose the ability to grow in media containing low levels (0.2 mM) of potassium.	Potassium	98-107	Trk1p	Saccharomyces cerevisiae S288C	56-60
2199313-2	1990	Using a trk1 delta strain, we selected spontaneous Trk+ pseudorevertants that regained the ability to grow on low concentrations of potassium.	Potassium	132-141	Trk1p	Saccharomyces cerevisiae S288C	8-12
2199313-4	1990	Dominant RPD2 mutations and recessive rpd1 and rpd3 mutations confer increased potassium uptake in trk1 delta cells.	Potassium	79-88	Trk2p	Saccharomyces cerevisiae S288C	9-13
2199313-4	1990	Dominant RPD2 mutations and recessive rpd1 and rpd3 mutations confer increased potassium uptake in trk1 delta cells.	Potassium	79-88	transcriptional regulator SIN3	Saccharomyces cerevisiae S288C	38-42
2199313-4	1990	Dominant RPD2 mutations and recessive rpd1 and rpd3 mutations confer increased potassium uptake in trk1 delta cells.	Potassium	79-88	histone deacetylase RPD3	Saccharomyces cerevisiae S288C	47-51
2199313-4	1990	Dominant RPD2 mutations and recessive rpd1 and rpd3 mutations confer increased potassium uptake in trk1 delta cells.	Potassium	79-88	Trk1p	Saccharomyces cerevisiae S288C	99-103
2370646-2	1990	We have previously demonstrated, by giving an infusion of terbutaline to human volunteers, that beta 2-stimulation causes a rise in plasma glucose and a fall in plasma potassium.	Potassium	168-177	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	96-102
1693429-5	1990	The IL-6-R was functional, as [3H]thymidine incorporation by AIDS-KS cells increased significantly after exposure to human recombinant IL-6 (hrIL-6) at greater than 10 units/ml.	Potassium	66-68	interleukin 6 receptor	Homo sapiens	4-10
1693429-5	1990	The IL-6-R was functional, as [3H]thymidine incorporation by AIDS-KS cells increased significantly after exposure to human recombinant IL-6 (hrIL-6) at greater than 10 units/ml.	Potassium	66-68	interleukin 6	Homo sapiens	4-8
1693429-11	1990	These results show that both IL-6 and IL-6-R are produced by AIDS-KS cells and that IL-6 is required for optimal AIDS-KS cell proliferation, and they suggest that IL-6 is an autocrine growth factor for AIDS-KS cells.	Potassium	66-68	interleukin 6	Homo sapiens	29-33
1693429-11	1990	These results show that both IL-6 and IL-6-R are produced by AIDS-KS cells and that IL-6 is required for optimal AIDS-KS cell proliferation, and they suggest that IL-6 is an autocrine growth factor for AIDS-KS cells.	Potassium	66-68	interleukin 6 receptor	Homo sapiens	38-44
1693429-11	1990	These results show that both IL-6 and IL-6-R are produced by AIDS-KS cells and that IL-6 is required for optimal AIDS-KS cell proliferation, and they suggest that IL-6 is an autocrine growth factor for AIDS-KS cells.	Potassium	66-68	interleukin 6	Homo sapiens	38-42
1693429-11	1990	These results show that both IL-6 and IL-6-R are produced by AIDS-KS cells and that IL-6 is required for optimal AIDS-KS cell proliferation, and they suggest that IL-6 is an autocrine growth factor for AIDS-KS cells.	Potassium	66-68	interleukin 6	Homo sapiens	38-42
2161530-0	1990	Muscarinic and beta-adrenergic depression of the slow Ca2(+)-activated potassium conductance in hippocampal CA3 pyramidal cells is not mediated by a reduction of depolarization-induced cytosolic Ca2+ transients.	Potassium	71-80	carbonic anhydrase 2	Homo sapiens	54-57
2161530-0	1990	Muscarinic and beta-adrenergic depression of the slow Ca2(+)-activated potassium conductance in hippocampal CA3 pyramidal cells is not mediated by a reduction of depolarization-induced cytosolic Ca2+ transients.	Potassium	71-80	carbonic anhydrase 3	Homo sapiens	108-111
2161530-1	1990	Combined intracellular and microfluorometric recording techniques were used to evaluate whether the inhibition by cholinergic or adrenergic transmitters of the Ca2(+)-activated potassium current (IAHP) in hippocampal CA3 pyramidal cells was mediated by an alteration of depolarization-induced change in cytosolic free Ca2+ concentration [(Ca2+]i).	Potassium	177-186	carbonic anhydrase 2	Homo sapiens	160-163
19215353-6	1990	The ability of potassium and glutamate to cause a mean 50% increase of ANP secretion above baseline was abolished after deleting calcium chloride from the medium.	Potassium	15-24	natriuretic peptide A	Rattus norvegicus	71-74
2161530-1	1990	Combined intracellular and microfluorometric recording techniques were used to evaluate whether the inhibition by cholinergic or adrenergic transmitters of the Ca2(+)-activated potassium current (IAHP) in hippocampal CA3 pyramidal cells was mediated by an alteration of depolarization-induced change in cytosolic free Ca2+ concentration [(Ca2+]i).	Potassium	177-186	carbonic anhydrase 3	Homo sapiens	217-220
2140017-7	1990	ProANF-(1-30), (79-98), and ANF significantly (P less than 0.05) increased urinary potassium excretion.	Potassium	83-92	natriuretic peptide A	Rattus norvegicus	3-6
2140359-2	1990	At pH 7.0 and 5 degrees C, in the absence of potassium and magnesium, the Ca-ATPase of the sarcoplasmic reticulum slowly hydrolyzes the Ca.ATP at a rate of 0.05 s-1.	Potassium	45-54	dynein axonemal heavy chain 8	Homo sapiens	77-83
2140025-4	1990	Atriopeptin II significantly decreased mean aortic pressure (-12%), GFR (-40%), V (-66%), and the absolute excretion rates of sodium (-47%), potassium (-43%), and total osmolytes (-44%).	Potassium	141-150	natriuretic peptide A	Homo sapiens	0-11
2340265-1	1990	The reactivity of simple alkyl thiolates with N-ethylmaleimide (NEM) follows the Bronsted equation, log kS- = log G + beta pK, with G = 790 M-1 min-1 and beta = 0.43.	Potassium	104-106	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2335026-4	1990	Our aim was twofold: 1) to study the single-channel characteristics of potassium channels in human atrial single cells, present under basal conditions (iK1 and iK(ATP] or when stimulated with 10(-5) M acetylcholine; and 2) to calculate the contribution of these three channel types to the total basal potassium conductance in human atrial cells, and to compare the results with data on guinea pig atrial cells under the same conditions.	Potassium	71-80	IKAROS family zinc finger 1	Homo sapiens	152-155
2335026-10	1990	The basal potassium conductance (i.e., in the absence of any exogenous hormone or neurotransmitter) was mainly due to iK1 channels in both human and guinea pig cells, a finding that is in contrast with previous reports.	Potassium	10-19	IKAROS family zinc finger 1	Homo sapiens	118-121
2199945-3	1990	Potassium-stimulated release of immunoreactive cGnRH-I and cGnRH-II from brain regions was assessed in tissue incubations.	Potassium	0-9	gonadotropin releasing hormone 1	Gallus gallus	47-54
2199945-7	1990	Potassium stimulated the release of cGnRH-I from the median eminence 4-fold, while cGnRH-II release was not detectable.	Potassium	0-9	gonadotropin releasing hormone 1	Gallus gallus	36-43
2161700-9	1990	High potassium concentrations induced a marked increase of alpha-MSH release from both tissue preparations.	Potassium	5-14	proopiomelanocortin	Rattus norvegicus	59-68
1970125-0	1990	[Decrease in serum potassium level caused by beta 2-sympathicomimetics].	Potassium	19-28	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	45-51
2180594-5	1990	Thus, in the doses used, endothelin-1 induces a rise in blood pressure and serum potassium concentrations.	Potassium	81-90	endothelin 1	Homo sapiens	25-37
2181872-2	1990	Insulin, epinephrine, and aldosterone all play major roles in maintaining the normal distribution of potassium between the intracellular and extracellular environment.	Potassium	101-110	insulin	Homo sapiens	0-7
2373550-1	1990	Treatment of renal anemia with recombinant human erythropoietin in chronic hemodialysis patients has been reported to lead to increased appetite, and in several studies, to an increase in predialysis serum urea, potassium and creatinine values.	Potassium	212-221	erythropoietin	Homo sapiens	49-63
2109786-0	1990	A voltage-clamp analysis of gene-dosage effects of the Shaker locus on larval muscle potassium currents in Drosophila.	Potassium	85-94	Shaker	Drosophila melanogaster	55-61
2109786-1	1990	Mutations of the Shaker (Sh) locus of Drosophila reduce, eliminate, or otherwise alter a transient potassium current, IA, in muscle.	Potassium	99-108	Shaker	Drosophila melanogaster	17-23
2109786-1	1990	Mutations of the Shaker (Sh) locus of Drosophila reduce, eliminate, or otherwise alter a transient potassium current, IA, in muscle.	Potassium	99-108	Shaker	Drosophila melanogaster	17-19
2309625-2	1990	Total body potassium is reduced, and this reduction bears a modest relation to activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system.	Potassium	11-20	renin	Homo sapiens	132-137
19210371-6	1990	Stimulation of dendrosomes with 56 mM potassium in the presence of tannic acid, which preserves exocytosed granule cores so that they can be visualized electron microscopically, demonstrates that, in response to a depolarizing stimulus, dendrosomes are capable of secreting by exocytosis the neuropeptides oxytocin (OT) and vasopressin (VP) and their co-packaged neurophysins.	Potassium	38-47	arginine vasopressin	Homo sapiens	324-335
19210371-6	1990	Stimulation of dendrosomes with 56 mM potassium in the presence of tannic acid, which preserves exocytosed granule cores so that they can be visualized electron microscopically, demonstrates that, in response to a depolarizing stimulus, dendrosomes are capable of secreting by exocytosis the neuropeptides oxytocin (OT) and vasopressin (VP) and their co-packaged neurophysins.	Potassium	38-47	arginine vasopressin	Homo sapiens	337-339
1971430-1	1990	The ability of (-)N-n-propylnorapomorphine and selective D1 and D2 dopamine receptor agonists and antagonists to modify the release of [3H]dopamine, induced by potassium from the nucleus accumbens, was studied using an in vitro superfusion technique.	Potassium	160-169	dopamine receptor D2	Rattus norvegicus	64-84
2178375-4	1990	Activation of the renin-angiotensin system may also cause potassium depletion, which is manifest clinically by a decrease in both total body potassium and serum potassium concentration.	Potassium	58-67	renin	Homo sapiens	18-23
2178375-4	1990	Activation of the renin-angiotensin system may also cause potassium depletion, which is manifest clinically by a decrease in both total body potassium and serum potassium concentration.	Potassium	141-150	renin	Homo sapiens	18-23
2180321-5	1990	Insulin caused transient sodium and potassium retention followed by renal "escape" that was associated with increased glomerular filtration rate (12-27%).	Potassium	36-45	insulin	Canis lupus familiaris	0-7
2178375-4	1990	Activation of the renin-angiotensin system may also cause potassium depletion, which is manifest clinically by a decrease in both total body potassium and serum potassium concentration.	Potassium	141-150	renin	Homo sapiens	18-23
2178376-6	1990	Although diuretic use is the most frequent cause of hypokalemia, epinephrine can also lower serum potassium as a result of stimulation of the beta 2 adrenoreceptor.	Potassium	98-107	adrenoceptor beta 2	Homo sapiens	142-163
2178378-7	1990	In experimental and clinical hypertension, an increased intake of potassium (without a change in dietary sodium) can reduce blood pressure, may suppress the activity of the sympathetic nervous and renin-angiotensin systems, and can prevent the development of vascular injury; conversely, potassium depletion has been associated with an increase in stroke and sudden death.	Potassium	66-75	renin	Homo sapiens	197-202
2138899-7	1990	After ANP infusion there was a prompt restoration of GFR, with a large rise in urine, sodium and potassium excretion rates.	Potassium	97-106	natriuretic peptide A	Rattus norvegicus	6-9
2155616-1	1990	K-259-2 and KS-619-1, novel anionic anthraquinone metabolites isolated from culture broth of microorganisms, inhibited activation of bovine brain phosphodiesterase induced by calmodulin (CaM), sodium oleate, or limited proteolysis with almost equal potency.	Potassium	12-14	calmodulin	Bos taurus	175-185
2155616-1	1990	K-259-2 and KS-619-1, novel anionic anthraquinone metabolites isolated from culture broth of microorganisms, inhibited activation of bovine brain phosphodiesterase induced by calmodulin (CaM), sodium oleate, or limited proteolysis with almost equal potency.	Potassium	12-14	calmodulin	Bos taurus	187-190
2155616-2	1990	The inhibition of calmodulin-activated phosphodiesterase (CaM-PDE) by K-259-2 or KS-619-1 was overcome by a higher concentration of CaM.	Potassium	81-83	calmodulin	Bos taurus	18-28
2155616-2	1990	The inhibition of calmodulin-activated phosphodiesterase (CaM-PDE) by K-259-2 or KS-619-1 was overcome by a higher concentration of CaM.	Potassium	81-83	calmodulin	Bos taurus	58-61
2155616-2	1990	The inhibition of calmodulin-activated phosphodiesterase (CaM-PDE) by K-259-2 or KS-619-1 was overcome by a higher concentration of CaM.	Potassium	81-83	calmodulin	Bos taurus	132-135
2155616-3	1990	Direct interaction of K-259-2 and KS-619-1 with CaM was confirmed through use of hydrophobic fluorescent probes.	Potassium	34-36	calmodulin	Bos taurus	48-51
2155616-5	1990	Addition of a lower amount of either phosphatidylserine or sodium oleate to the reaction mixture was efficacious in attenuating the inhibition of the CaM-PDE by W-7, chlorpromazine, trifluoperazine, compound 48/80, or R-24571 but, in contrast, had little or no effect on the inhibition by K-259-2 or KS-619-1.	Potassium	300-302	calmodulin	Bos taurus	150-153
2158468-2	1990	ATPase activity was investigated in sciatic and optic nerves of female mutant diabetic C57Bl/Ks (db/db) mice and age-matched control mice (db/m and m/m).	Potassium	93-95	dynein, axonemal, heavy chain 8	Mus musculus	0-6
15539200-0	1990	Insulin secretion and glucose uptake in hypomagnesemic sheep fed a low magnesium, high potassium diet.	Potassium	87-96	LOC105613195	Ovis aries	0-7
2340419-1	1990	Both potassium and rubidium can flow through the Ca2(+)-activated K channel of human erythrocytes.	Potassium	5-14	carbonic anhydrase 2	Homo sapiens	49-52
2179231-0	1990	Macrophage-colony-stimulating factor (CSF-1) modulates a differentiation-specific inward-rectifying potassium current in human leukemic (HL-60) cells.	Potassium	100-109	colony stimulating factor 1	Homo sapiens	38-43
2307976-4	1990	The expression of p65 in ganglion explants increased by 40-100% when the cultures were treated with the depolarizing agents, veratridine or high potassium.	Potassium	145-154	synaptotagmin 1	Rattus norvegicus	18-21
1693683-8	1990	Potassium currents were also reversibly suppressed by 8 nM-charybdotoxin but unaffected by 100 nM-apamin, suggesting that the Ca2(+)-dependent K+ current was carried through large or intermediate conductance Ca2(+)-activated K+ channels.	Potassium	0-9	carbonic anhydrase 2	Rattus norvegicus	126-129
2141079-23	1990	It is concluded that the IPSP in PH cells is caused by 5-HT acting on 5-HT1A receptors to activate a potassium conductance.	Potassium	101-110	5-hydroxytryptamine receptor 1A	Cavia porcellus	70-76
1693683-8	1990	Potassium currents were also reversibly suppressed by 8 nM-charybdotoxin but unaffected by 100 nM-apamin, suggesting that the Ca2(+)-dependent K+ current was carried through large or intermediate conductance Ca2(+)-activated K+ channels.	Potassium	0-9	carbonic anhydrase 2	Rattus norvegicus	208-211
19210391-2	1990	The facts that immunoreactive ANF (ir-ANF) is also present in nerve terminals in the external layer of the median eminence (ME) (5), ir-ANF can be released from the hypothalamus in vitro by potassium depolarization (6) and specific ANF binding sites are present at a high concentration in rat pituitary tissue (7) suggest that ANF may be involved in hypothalamic-pituitary regulation.	Potassium	190-199	natriuretic peptide A	Rattus norvegicus	30-33
2108785-3	1990	The depolarizing response and membrane conductance change was the result of a direct postsynaptic action of TRH, possibly mediated by a reduction of a potassium conductance.	Potassium	151-160	thyrotropin releasing hormone	Cavia porcellus	108-111
2155002-8	1990	Alternatively, insulin might alter sodium/potassium distribution thus causing increased vascular peripheral resistance.	Potassium	42-51	insulin	Homo sapiens	15-22
2303281-8	1990	At 60 weeks of age, rats that received perinatal low salt diet had significantly heavier adrenal glands when compared with the other groups, and the high potassium group had significantly elevated plasma renin concentrations.	Potassium	154-163	renin	Rattus norvegicus	204-209
2313342-8	1990	The CA1 region had 1) a higher frequency of spontaneous SD episodes than CA3, 2) a lower threshold to potassium-triggered SD, 3) a longer duration SD episode, and 4) smaller post-SD membrane potential and [K+]o undershoots (below the original resting membrane potential and resting [K+]o).	Potassium	102-111	carbonic anhydrase 1	Oryctolagus cuniculus	4-7
19210391-2	1990	The facts that immunoreactive ANF (ir-ANF) is also present in nerve terminals in the external layer of the median eminence (ME) (5), ir-ANF can be released from the hypothalamus in vitro by potassium depolarization (6) and specific ANF binding sites are present at a high concentration in rat pituitary tissue (7) suggest that ANF may be involved in hypothalamic-pituitary regulation.	Potassium	190-199	natriuretic peptide A	Rattus norvegicus	38-41
19210391-2	1990	The facts that immunoreactive ANF (ir-ANF) is also present in nerve terminals in the external layer of the median eminence (ME) (5), ir-ANF can be released from the hypothalamus in vitro by potassium depolarization (6) and specific ANF binding sites are present at a high concentration in rat pituitary tissue (7) suggest that ANF may be involved in hypothalamic-pituitary regulation.	Potassium	190-199	natriuretic peptide A	Rattus norvegicus	38-41
19210391-2	1990	The facts that immunoreactive ANF (ir-ANF) is also present in nerve terminals in the external layer of the median eminence (ME) (5), ir-ANF can be released from the hypothalamus in vitro by potassium depolarization (6) and specific ANF binding sites are present at a high concentration in rat pituitary tissue (7) suggest that ANF may be involved in hypothalamic-pituitary regulation.	Potassium	190-199	natriuretic peptide A	Rattus norvegicus	38-41
19210391-2	1990	The facts that immunoreactive ANF (ir-ANF) is also present in nerve terminals in the external layer of the median eminence (ME) (5), ir-ANF can be released from the hypothalamus in vitro by potassium depolarization (6) and specific ANF binding sites are present at a high concentration in rat pituitary tissue (7) suggest that ANF may be involved in hypothalamic-pituitary regulation.	Potassium	190-199	natriuretic peptide A	Rattus norvegicus	38-41
2336813-5	1990	The trend of rising potassium levels must be foreseen in case of a poor compensation even in case of insulin treatment of diabetes.	Potassium	20-29	insulin	Homo sapiens	101-108
2308263-8	1990	Thus, the higher rise in potassium concentration during exercise with propranolol could only be explained by adrenergic blockade at the beta-2 receptor site.	Potassium	25-34	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	136-142
2308263-9	1990	These results support the concept that adrenergic control of extrarenal potassium homeostasis in dialysis patients is mediated at the beta-2 receptor.	Potassium	72-81	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	134-140
2308263-10	1990	Since a deterioration in potassium homeostasis during exercise is observed with beta-2, but not beta-1 blockade, selective beta-1 adrenergic blocking agents may be safer in dialysis patients.	Potassium	25-34	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	80-86
2308263-10	1990	Since a deterioration in potassium homeostasis during exercise is observed with beta-2, but not beta-1 blockade, selective beta-1 adrenergic blocking agents may be safer in dialysis patients.	Potassium	25-34	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	123-129
1967972-0	1990	gamma-Aminobutyric acid inhibits the potassium-stimulated release of somatostatin from rat spinal cord slices.	Potassium	37-46	somatostatin	Rattus norvegicus	69-81
2337775-1	1990	Angiotensin II was shown to inhibit potassium-stimulated release of [3H]acetylcholine from slices of fresh human temporal cortex, obtained at surgery, and subsequently loaded with [3H]choline for the biochemical analyses.	Potassium	36-45	angiotensinogen	Homo sapiens	0-14
2302182-3	1990	Although the ks of total protein and actin were doubled at 24 h, the ks for SM1 and SM2 were depressed.	Potassium	69-71	slow myosin heavy chain 1	Gallus gallus	76-79
2302182-3	1990	Although the ks of total protein and actin were doubled at 24 h, the ks for SM1 and SM2 were depressed.	Potassium	69-71	myosin, heavy chain 7B, cardiac muscle, beta	Gallus gallus	84-87
1967972-2	1990	Since gamma-aminobutyric acid (GABA), norepinephrine, and morphine alter nociception at the level of the spinal cord, we examined whether these agents could alter the potassium-stimulated release of somatostatin from rat spinal cord slices.	Potassium	167-176	somatostatin	Rattus norvegicus	199-211
1967972-7	1990	Pre-exposure of tissue to GABA at 10(-4) and 10(-5) M significantly inhibited the potassium-stimulated release of SO, but did not alter basal release.	Potassium	82-91	somatostatin	Rattus norvegicus	114-116
2248802-6	1990	The potassium content of the serum of the diabetics was significantly decreased by insulin administration.	Potassium	4-13	insulin	Homo sapiens	83-90
2151009-1	1990	We investigated the effect of intraventricularly administered atrial natriuretic peptide (ANP) on the brain water, sodium and potassium contents in ischaemic brain oedema.	Potassium	126-135	natriuretic peptide A	Rattus norvegicus	62-88
1983458-1	1990	Studies were undertaken to characterize the participation of specific alpha-1,alpha-2 and beta adrenoceptors of the lateral hypothalamic area (LHA) in the urinary excretion of sodium and potassium.	Potassium	187-196	adrenoceptor alpha 1D	Homo sapiens	70-77
2244994-4	1990	The 95% limits of agreement between Ionometer EF2 and flame photometry were for potassium -0.29 and 0.43 mmol/l and for sodium -5.0 and 2.89 mmol/l, respectively.	Potassium	80-89	eukaryotic translation elongation factor 2	Homo sapiens	46-49
1983458-2	1990	Alpha-1 and alpha-2 LHA receptors were shown to participate in the regulation of renal sodium and potassium excretion.	Potassium	98-107	adrenoceptor alpha 1D	Homo sapiens	0-7
2114198-7	1990	Within the inner hair cells, parvalbumin may be involved in the ionic regulation following potassium entry during the transduction process.	Potassium	91-100	parvalbumin alpha	Cavia porcellus	29-40
2302557-0	1990	Effects of extracellular potassium concentration and postsynaptic membrane potential on calcium-induced potentiation in area CA1 of rat hippocampus.	Potassium	25-34	carbonic anhydrase 1	Rattus norvegicus	125-128
2257720-7	1990	ACE inhibition also prevents secondary aldosteronism and thereby avoids renal potassium loss.	Potassium	78-87	angiotensin I converting enzyme	Homo sapiens	0-3
12106023-6	1990	Potassium-stimulated, Ca2+-dependent release of [3H]glutamate in synaptosomes prepared from the dentate gyrus and area CA3 was significantly greater in conditioned animals than in pseudoconditioned animals.	Potassium	0-9	carbonic anhydrase 2	Rattus norvegicus	22-25
12106023-6	1990	Potassium-stimulated, Ca2+-dependent release of [3H]glutamate in synaptosomes prepared from the dentate gyrus and area CA3 was significantly greater in conditioned animals than in pseudoconditioned animals.	Potassium	0-9	carbonic anhydrase 3	Rattus norvegicus	119-122
2146224-0	1990	Extracellular potassium influences DNA and protein syntheses and glial fibrillary acidic protein expression in cultured glial cells.	Potassium	14-23	glial fibrillary acidic protein	Gallus gallus	65-96
2146224-1	1990	Previous reports of increases in glial cell number and expression of glial fibrillary acidic protein (GFAP) in stimulated brain regions or epileptic tissue have implicated a role for increases in extracellular potassium concentration ([K+]o) in glial reactions.	Potassium	210-219	glial fibrillary acidic protein	Gallus gallus	69-100
2146224-1	1990	Previous reports of increases in glial cell number and expression of glial fibrillary acidic protein (GFAP) in stimulated brain regions or epileptic tissue have implicated a role for increases in extracellular potassium concentration ([K+]o) in glial reactions.	Potassium	210-219	glial fibrillary acidic protein	Gallus gallus	102-106
11527136-8	1990	Beta1-blockers additionally influence the cellular potassium homeostasis to a substantially lower extent.	Potassium	51-60	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	0-5
2174633-6	1990	The addition of the NMDA receptor antagonist D-2-amino-7-phosphonoheptanoate (APH) blocked the trophic effect of 10 mM potassium in tetrodotoxin-grown cultures, resulting in low survival.	Potassium	119-128	acylaminoacyl-peptide hydrolase	Homo sapiens	78-81
2141843-4	1990	Transmembrane potassium distribution is influenced largely by acid-base equilibrium and hormones including insulin and catecholamines.	Potassium	14-23	insulin	Homo sapiens	107-114
2154581-2	1990	This protein, termed IsK protein, is small and different from the conventional potassium channel proteins but induces selective permeation of potassium ions on its expression in Xenopus oocytes.	Potassium	79-88	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	21-24
2154581-7	1990	Thus, taking into account the cellular localization of the IsK protein, together with its electrophysiological properties, we discussed a possible function of the IsK protein, namely that this protein is involved in potassium permeation in the apical membrane of epithelial cells through the depolarizing effect of sodium entry.	Potassium	216-225	potassium voltage-gated channel subfamily E regulatory subunit 1	Rattus norvegicus	163-166
2182997-1	1990	Parathyroid hormone (PTH) impairs extrarenal disposal of potassium in both acute and chronic renal failure.	Potassium	57-66	parathyroid hormone	Homo sapiens	0-19
2299401-8	1990	The phospholipase A2 inhibitors quinacrine hydrochloride, trifluoperazine, and 4-bromophenacylbromide dose-dependently inhibited potassium depolarization-induced activation of specific 3H-HCh-3 binding in slices of rat brain in vitro.	Potassium	129-138	phospholipase A2 group IB	Rattus norvegicus	4-20
2148203-6	1990	At higher infusion rates ET-3 markedly decreased the GFR, urine flow and urinary potassium excretion.	Potassium	81-90	endothelin 3	Rattus norvegicus	25-29
2182997-1	1990	Parathyroid hormone (PTH) impairs extrarenal disposal of potassium in both acute and chronic renal failure.	Potassium	57-66	parathyroid hormone	Homo sapiens	21-24
2182997-4	1990	Since patients with chronic renal failure have elevated blood levels of PTH, the effect of the hormone on extrarenal disposal of potassium should have important clinical implications.	Potassium	129-138	parathyroid hormone	Homo sapiens	72-75
2182997-5	1990	Chronic renal failure patients with higher blood levels of PTH may be at a greater risk of hyperkalemia when exposed to a potassium load than those with lower levels of PTH.	Potassium	122-131	parathyroid hormone	Homo sapiens	59-62
2182997-6	1990	Thus, in developing dietary regimens for potassium intake to patients with chronic renal failure, their blood levels of PTH should be taken into consideration in such dietary planning.	Potassium	41-50	parathyroid hormone	Homo sapiens	120-123
1694311-1	1990	The effect was examined of the chemical decomposition of the potassium stain sodium hexanitrocobaltate (III) (SHC), on its ability to produce stain granules of consistent size that could be used to estimate the K+ contents of stomatal guard cells.	Potassium	61-70	SHC adaptor protein 1	Homo sapiens	110-113
2243598-4	1990	In addition, release of acetylcholinesterase could be evoked by either pharmacological or physiological manipulations, i.e. (1) a depolarizing concentration of potassium ions administered locally; (2) metamphetamine, administered systematically, which also resulted in increased locomotor activity; (3) drinking behaviour, elicited by presentation of a water bottle.	Potassium	160-169	acetylcholinesterase	Cavia porcellus	24-44
2355308-4	1990	Addition of danazol to microsomal preparation resulted in a reverse type I difference spectrum and the spectrophotometric analysis revealed that danazol had a high affinity for cytochrome P-450 with dissociation constants (Ks) of 0.9 and 4.2 microM, which were 2 orders of magnitude lower than those of cimetidine.	Potassium	223-225	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	177-193
33772588-0	2021	Induction of S-nitrosoglutathione reductase protects root growth from ammonium toxicity by regulating potassium homeostasis in Arabidopsis and rice.	Potassium	102-111	GroES-like zinc-binding dehydrogenase family protein	Arabidopsis thaliana	13-43
1968675-7	1990	It was evident that chronic exposure to high potassium concentrations modified the elution profile of medium IR-SRIF on HPLC and gel filtration, causing an increase in somatostatin-28 (S-28) and a decrease in somatostatin-14 (S-14).	Potassium	45-54	somatostatin	Homo sapiens	168-183
1968675-7	1990	It was evident that chronic exposure to high potassium concentrations modified the elution profile of medium IR-SRIF on HPLC and gel filtration, causing an increase in somatostatin-28 (S-28) and a decrease in somatostatin-14 (S-14).	Potassium	45-54	somatostatin	Homo sapiens	209-224
33818128-7	2021	Renal clearance experiments showed that HS intake for two-weeks increased the basal level of renal K+ excretion and caused hypokalemia in Ks-Nedd4-2-KO mice but not in Nedd4lflox/flox mice.	Potassium	138-140	neural precursor cell expressed, developmentally down-regulated gene 4-like	Mus musculus	141-148
33972751-4	2021	Cd2+ induced hypertension in vivo by significantly (p < 0.001) elevating systolic blood pressure (160 +- 2 and 155 +- 1 vs 120 +- 1 mm Hg), diastolic blood pressure (119 +- 2 and 110 +- 1 vs 81 +- 1 mm Hg), and mean arterial pressure (133 +- 2 and 125 +- 1 vs 94 +- 1 mm Hg) (SBP, DBP, and MAP, respectively), while potassium supplementation protected against elevation of these parameters.	Potassium	316-325	Cd2 molecule	Rattus norvegicus	0-3
33588076-0	2021	ATP Binding Cassette Proteins ABCG37 and ABCG33 function as potassium-independent cesium uptake carriers in Arabidopsis roots.	Potassium	60-69	pleiotropic drug resistance 9	Arabidopsis thaliana	30-36
33822868-1	2021	Inwardly rectifying potassium (Kir) channels are broadly expressed in both excitable and nonexcitable tissues, where they contribute to a wide variety of cellular functions.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
33822868-4	2021	This novel intrinsic rectification originates from the voltage-dependent behavior of Kir4.1/Kir5.1, which is generated by the flux of potassium ions through the channel pore; the inward K+-flux induces the opening of the gate, whereas the outward flux is unable to maintain the gate open.	Potassium	134-143	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	85-91
33822868-4	2021	This novel intrinsic rectification originates from the voltage-dependent behavior of Kir4.1/Kir5.1, which is generated by the flux of potassium ions through the channel pore; the inward K+-flux induces the opening of the gate, whereas the outward flux is unable to maintain the gate open.	Potassium	134-143	potassium inwardly rectifying channel subfamily J member 16	Homo sapiens	92-98
33588076-0	2021	ATP Binding Cassette Proteins ABCG37 and ABCG33 function as potassium-independent cesium uptake carriers in Arabidopsis roots.	Potassium	60-69	pleiotropic drug resistance 5	Arabidopsis thaliana	41-47
33588076-8	2021	Potassium response and content were unaffected in the double mutant background and the yeast cells lacking potassium uptake carriers transformed with ABCG33 and ABCG37 failed to grow in absence of K+, confirming that Cs+ uptake by ABCG33 and ABCG37 is independent of K+.	Potassium	107-116	pleiotropic drug resistance 5	Arabidopsis thaliana	231-237
33800655-2	2021	An enzyme responsible for this process, sodium-potassium ATPase (NKA), has been currently extensively studied as a potential anticancer target, especially in lung cancer and glioblastoma.	Potassium	47-56	tachykinin precursor 1	Homo sapiens	65-68
33766732-2	2021	The M-current, a subthreshold, non-inactivating potassium current plays a critical role in regulating NPY/AgRP neuronal excitability.	Potassium	48-57	neuropeptide Y	Mus musculus	102-105
33766732-2	2021	The M-current, a subthreshold, non-inactivating potassium current plays a critical role in regulating NPY/AgRP neuronal excitability.	Potassium	48-57	agouti related neuropeptide	Mus musculus	106-110
33159577-4	2021	IL-6 was involved in the modulation of sodium-potassium-chloride cotransporter (Nkcc) activity.	Potassium	46-55	interleukin 6	Rattus norvegicus	0-4
33807999-4	2021	Nckx3, a potassium-dependent Na+/Ca2+ exchanger, is not only expressed in the brain but also in the aortic, uterine, and intestinal tissues, which contain abundant smooth muscle cells.	Potassium	9-18	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	0-5
33234610-4	2021	Whole-cell patch-clamp recordings of neurons from male mouse ovBNST in vitro showed that BDNF/TrkB interaction causes a hyperpolarizing shift of the membrane potential from resting value, mediated by an inwardly rectifying potassium current, resulting in reduced neuronal excitability in all major types of ovBNST neurons.	Potassium	223-232	brain derived neurotrophic factor	Mus musculus	89-93
33234610-4	2021	Whole-cell patch-clamp recordings of neurons from male mouse ovBNST in vitro showed that BDNF/TrkB interaction causes a hyperpolarizing shift of the membrane potential from resting value, mediated by an inwardly rectifying potassium current, resulting in reduced neuronal excitability in all major types of ovBNST neurons.	Potassium	223-232	neurotrophic tyrosine kinase, receptor, type 2	Mus musculus	94-98
22286118-2	2011	Most cases are caused by mutations in KCNJ2, encoding for the potassium inwardly rectifying channel, Kir2.1 (ATS1).	Potassium	62-71	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	38-43
33234610-11	2021	BDNF/TrkB signaling dampens neuronal excitability through increase in membrane potassium conductance and long-term depression (LTD) of synaptic activity in all types of ovBNST neurons.	Potassium	79-88	brain derived neurotrophic factor	Mus musculus	0-4
33234610-11	2021	BDNF/TrkB signaling dampens neuronal excitability through increase in membrane potassium conductance and long-term depression (LTD) of synaptic activity in all types of ovBNST neurons.	Potassium	79-88	neurotrophic tyrosine kinase, receptor, type 2	Mus musculus	5-9
32884433-2	2020	The Kv1.5 channel is a potassium ion channel expressed in atrial muscle, belongs to the voltage-gated K+ channel superfamily, and forms an ultrarapid delayed rectifier potassium ion current.	Potassium	23-32	potassium voltage-gated channel subfamily A member 5	Homo sapiens	4-9
20882268-0	2011	Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial.	Potassium	16-25	angiotensinogen	Homo sapiens	118-132
22286118-2	2011	Most cases are caused by mutations in KCNJ2, encoding for the potassium inwardly rectifying channel, Kir2.1 (ATS1).	Potassium	62-71	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	101-107
19324862-7	2009	TGF-beta1- and FGF-2-induced decreases in cell-associated and secreted KS, and lumican mRNA levels were prevented by Rho or ROCK inhibition.	Potassium	71-73	fibroblast growth factor 2	Oryctolagus cuniculus	15-20
17902527-6	2007	The biophysical fingerprint of Kir channels is inward rectification in the current-voltage relationship , which limits potassium efflux at depolarizing membrane potentials.	Potassium	119-128	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
17902527-7	2007	Kir channels are essential in the control of resting membrane potential, coupling of the metabolic cellular state with membrane excitability, and maintenance of potassium homeostasis.	Potassium	161-170	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	0-3
34713909-0	2022	Envisioning the role of inwardly rectifying potassium (Kir) channel in epilepsy.	Potassium	44-53	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	55-58
34713909-5	2022	In this regard, emerging evidence highlights the potential implication of inwardly rectifying potassium (Kir) channels in epileptogenesis.	Potassium	94-103	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	105-108
34843409-2	2022	TPNQ-sensitive K+ currents (ROMK) were smaller in both DCT2/iCNT and CCD of Ks-Nedd4-2-KO mice on normal diet than control mice.	Potassium	76-78	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	28-32
34853886-11	2022	With the KS test, there was a significant difference in administration of opiates, GABA-agonists, alpha-2 agonists, anti-psychotics, and "other" sedatives over the first 30 days in the ICU.	Potassium	9-11	glycoprotein hormone subunit alpha 2	Homo sapiens	98-105
34388569-0	2022	Heterostructure engineering of ultrathin SnS2/Ti3C2Tx nanosheets for high-performance potassium-ion batteries.	Potassium	86-95	sodium voltage-gated channel alpha subunit 11	Homo sapiens	41-45
34843658-12	2022	A low potassium diet significantly reduced ENaC but not ROMK activity in DCT2/CNT.	Potassium	6-15	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	43-47
34843409-2	2022	TPNQ-sensitive K+ currents (ROMK) were smaller in both DCT2/iCNT and CCD of Ks-Nedd4-2-KO mice on normal diet than control mice.	Potassium	76-78	neural precursor cell expressed, developmentally down-regulated 4	Mus musculus	79-84
34843409-5	2022	However, effects of dietary-K+ intake on ROMK channel activity were absent in Ks-Nedd4-2-KO mice since neither HK nor LK significantly affected TPNQ-sensitive K+ currents in DCT2/iCNT and CCD.	Potassium	78-80	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	41-45
34843409-7	2022	TPNQ-sensitive K+ currents in DCT2/iCNT and the CCD of Ks-Nedd4-2-KO mice on HK were similar to the control mice on LK.	Potassium	55-57	neural precursor cell expressed, developmentally down-regulated 4	Mus musculus	58-63
34843409-8	2022	Amiloride-sensitive Na+ currents in DCT2/iCNT and CCD were significantly higher in Ks-Nedd4-2-KO mice than floxed-Nedd4l mice on normal-K+-diet.	Potassium	83-85	neural precursor cell expressed, developmentally down-regulated 4	Mus musculus	86-91
34843409-10	2022	Moreover, HK-induced increase in amiloride-sensitive Na+-currents was larger in Ks-Nedd4-2-KO mice than the control mice.	Potassium	80-82	neural precursor cell expressed, developmentally down-regulated 4	Mus musculus	83-88
34099189-4	2022	RESULTS: Across disorders, genome-wide significant single nucleotide polymorphism-by-sex interaction was detected for a locus encompassing NKAIN2 (rs117780815, p = 3.2 x 10-8), which interacts with sodium/potassium-transporting ATPase (adenosine triphosphatase) enzymes, implicating neuronal excitability.	Potassium	205-214	sodium/potassium transporting ATPase interacting 2	Homo sapiens	139-145
34718095-9	2022	Finally, we found that AO led to a significant increase in potassium calcium-activated channel, subfamily N, member 4 (KCNN4) and reactive oxygen species (ROS) levels, along with decreased nuclear factor kappa B, p65 (NF-kappaB p65), in the female mouse livers.	Potassium	59-68	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	119-124
34176835-2	2022	We herein report a case of hypomagnesemia due to the long-term use of vonoprazan, a potassium-competitive acid blocker (P-CAB).	Potassium	84-93	neural proliferation, differentiation and control 1	Homo sapiens	122-125
34935140-4	2021	Canonical actions of the MR take place in epithelial cells of kidney, colon and sweat glands and contribute to sodium reabsorption, potassium secretion and extracellular volume homeostasis.	Potassium	132-141	nuclear receptor subfamily 3 group C member 2	Homo sapiens	25-27
34987507-5	2021	Instead, FK866 facilitated robust caspase-1 activation in BMDMs in the presence of NLRP3-activating signals such as ATP and nigericin, a potassium ionophore.	Potassium	137-146	caspase 1	Mus musculus	34-43
34987507-5	2021	Instead, FK866 facilitated robust caspase-1 activation in BMDMs in the presence of NLRP3-activating signals such as ATP and nigericin, a potassium ionophore.	Potassium	137-146	NLR family, pyrin domain containing 3	Mus musculus	83-88
34945271-10	2021	Ks correlated with CLT (r = -0.28), FVIII (r = -0.30), FIX (r = -0.38), fibrinogen (r = -0.41), ALT (r = -0.25), AST (r = -0.26), GGTP (r = -0.27) and vWF antigen (r = -0.30), (all p < 0.05).	Potassium	0-2	fibrinogen beta chain	Homo sapiens	72-82
34945271-10	2021	Ks correlated with CLT (r = -0.28), FVIII (r = -0.30), FIX (r = -0.38), fibrinogen (r = -0.41), ALT (r = -0.25), AST (r = -0.26), GGTP (r = -0.27) and vWF antigen (r = -0.30), (all p < 0.05).	Potassium	0-2	solute carrier family 17 member 5	Homo sapiens	113-116
34889107-7	2021	Elevation of the urinary potassium-to-sodium excretion ratio, reflective of mineralocorticoid receptor activity, was only observed in participants with renin-independent aldosteronism.	Potassium	25-34	nuclear receptor subfamily 3 group C member 2	Homo sapiens	76-102
34945271-10	2021	Ks correlated with CLT (r = -0.28), FVIII (r = -0.30), FIX (r = -0.38), fibrinogen (r = -0.41), ALT (r = -0.25), AST (r = -0.26), GGTP (r = -0.27) and vWF antigen (r = -0.30), (all p < 0.05).	Potassium	0-2	von Willebrand factor	Homo sapiens	151-154
34945271-12	2021	After adjustment for potential cofounders, TAFI antigen and GGTP were independent predictors of reduced Ks (OR 1.041 per 1% increase, 95% CI 1.009-1.081, p = 0.011 and OR 1.025 per 1 U/L increase, 95% CI 1.005-1.053, p = 0.033, respectively).	Potassium	104-106	carboxypeptidase B2	Homo sapiens	43-47
34919690-7	2021	Compared to wild type, Tshz3+/lacZ mice showed lower blood urea, phosphates, magnesium and potassium at 2 months of age.	Potassium	91-100	teashirt zinc finger family member 3	Mus musculus	23-28
34960084-2	2021	We recently demonstrated that potassium supplementation reduces FGF23 levels in pre-hypertensive individuals.	Potassium	30-39	fibroblast growth factor 23	Homo sapiens	64-69
34960084-3	2021	The aim of the current study was to address whether 24-h urinary potassium excretion, reflecting dietary potassium intake, is associated with FGF23, and whether FGF23 mediates the association between urinary potassium excretion and incident hypertension in the general population.	Potassium	65-74	fibroblast growth factor 23	Homo sapiens	142-147
34960084-7	2021	Urinary potassium excretion was inversely associated with FGF23, independent of age, sex, urinary sodium excretion, bone and mineral parameters, inflammation, and iron status (St. beta -0.02, p < 0.05).	Potassium	8-17	fibroblast growth factor 23	Homo sapiens	58-63
34265689-0	2021	Reduced graphene oxide supported ZIF-67 derived CoP enables high-performance potassium ion storage.	Potassium	77-86	caspase recruitment domain family member 16	Homo sapiens	48-51
34956324-6	2021	The HR-DSCR is annotated as an intergenic region between KCNJ6-201 transcript encoding for potassium inwardly rectifying channel subfamily J member 6 and DSCR4-201 transcript encoding Down syndrome critical region 4.	Potassium	91-100	potassium inwardly rectifying channel subfamily J member 6	Homo sapiens	57-62
34911869-2	2021	This study aimed to investigate the functions and underlying mechanism of potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) in DN.	Potassium	74-83	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	153-161
34959995-4	2021	The first quartile (26.423 +- 5.731 mmol/gCr) was defined as low urine potassium excretion.	Potassium	71-80	nuclear receptor subfamily 3 group C member 1	Homo sapiens	41-44
34678594-0	2021	GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.	Potassium	78-87	gap junction protein beta 1	Homo sapiens	0-4
34856559-0	2022	Association of Genetic Variants of Klotho with BP Responses to Dietary Sodium or Potassium Intervention and Long-Term BP Progression.	Potassium	81-90	klotho	Homo sapiens	35-41
34856559-12	2022	CONCLUSIONS: Common variants of the KL gene might modify individual BP sensitivity to sodium or potassium and influence the long-term progression of BP, suggesting a potential role in the development of salt-sensitive hypertension.	Potassium	96-105	klotho	Homo sapiens	36-38
34586467-7	2021	The relative abundance of Trk system potassium uptake protein, Kdp operon response regulator, and Na+/H+ antiporter in the samples exceeded 0.09%, 0.06%, and 0.02%, respectively, indicating that the Trk system plays a major role in the salt tolerance of halotolerant bacteria in Yinggehai coastal soils and sediments.	Potassium	37-46	neurotrophic receptor tyrosine kinase 1	Homo sapiens	26-29
34779336-7	2021	Serum potassium concentration was statistically related to albumin concentration in peritonitis patients.	Potassium	6-15	albumin	Homo sapiens	59-66
34586467-7	2021	The relative abundance of Trk system potassium uptake protein, Kdp operon response regulator, and Na+/H+ antiporter in the samples exceeded 0.09%, 0.06%, and 0.02%, respectively, indicating that the Trk system plays a major role in the salt tolerance of halotolerant bacteria in Yinggehai coastal soils and sediments.	Potassium	37-46	neurotrophic receptor tyrosine kinase 1	Homo sapiens	199-202
33535882-3	2021	This study was designed to identify the specific PKC isoform involved in the long-term regulation of I Ks current.	Potassium	103-105	protein kinase C alpha	Homo sapiens	49-52
34783627-9	2021	Moreover, long noncoding RNA potassium voltage-gated channel subfamily Q member 1 opposite strand/antisense transcript 1 (KCNQ1OT1) was identified to serve as a competing endogenous RNA for miR-212-3p to regulate MAPK1.	Potassium	29-38	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	122-130
34783627-9	2021	Moreover, long noncoding RNA potassium voltage-gated channel subfamily Q member 1 opposite strand/antisense transcript 1 (KCNQ1OT1) was identified to serve as a competing endogenous RNA for miR-212-3p to regulate MAPK1.	Potassium	29-38	mitogen-activated protein kinase 1	Homo sapiens	213-218
33535882-4	2021	The I Ks current was recorded using whole-cell patch-clamp technique in human embryonic kidney (HEK) 293B cell co-transfected with human KCNQ1/KCNE1 genes.	Potassium	6-8	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	137-142
33535882-6	2021	Further evidence showed that PKCepsilon knockdown by siRNA antagonized the AngII-induced chronic inhibition on the I Ks current, whereas knockdown of cPKC (PKCalpha and PKCbeta) attenuated the inhibition effect of PMA on the current.	Potassium	117-119	protein kinase C epsilon	Homo sapiens	29-39
34737802-7	2021	TRPA1 has a high permeability to Ca2+, sodium and potassium ions as a non-selective cation channel and the Ca2+ influx mediated by TRPA1 is involved in a variety of biological processes.	Potassium	50-59	transient receptor potential cation channel subfamily A member 1	Homo sapiens	131-136
34846564-0	2021	A spatial-temporal understanding of gene regulatory networks and NtARF-mediated regulation of potassium accumulation in tobacco.	Potassium	94-103	ADP-ribosylation factor 1-like	Nicotiana tabacum	65-70
34737802-7	2021	TRPA1 has a high permeability to Ca2+, sodium and potassium ions as a non-selective cation channel and the Ca2+ influx mediated by TRPA1 is involved in a variety of biological processes.	Potassium	50-59	transient receptor potential cation channel subfamily A member 1	Homo sapiens	0-5
34674267-4	2021	Pellino-2 showed cytoplasmic localization in a wide range of non-immune cells under physiological potassium concentrations.	Potassium	98-107	pellino E3 ubiquitin protein ligase family member 2	Homo sapiens	0-9
34674267-5	2021	Treatment with the potassium ionophore nigericin resulted in nuclear localization of Pellino-2, which was reversed by the potassium channel blocker TEA.	Potassium	19-28	pellino E3 ubiquitin protein ligase family member 2	Homo sapiens	85-94
34761437-1	2021	BACKGROUND: Long non-coding RNA potassium voltage-gated channel subfamily Q member 1 opposite strand 1 (lnc-KCNQ1OT1) represses inflammation and multiple organ dysfunction, whereas its clinical value in sepsis is unclear.	Potassium	32-41	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	108-116
34400182-8	2021	Changes in spontaneous activity and action potential were mediated by decreased hyperpolarization-activated current (If) and increased inward rectifier potassium currents (IK1), sodium currents (INa), and the rapidly and slowly activating delayed rectifier potassium currents (IKr and IKs, respectively).	Potassium	152-161	potassium calcium-activated channel subfamily N member 4	Homo sapiens	172-175
34838148-3	2021	RESULTS: There were positive correlation between potassium level with miR-34 (p  = 0.008, r  = 0.366), miR-148 (p  = 0.004, r  = 0.394) and miR-155 (p  = 0.031, r  = 0.300).	Potassium	49-58	microRNA 34a	Homo sapiens	70-76
34757159-1	2021	The human ether-a-go-go-related gene (hERG) encodes the Kv11.1 voltage-gated potassium ion (K+) channel that conducts the rapidly activating delayed rectifier current (Ikr) in cardiomyocytes to regulate the repolarization process.	Potassium	77-86	ETS transcription factor ERG	Homo sapiens	38-42
34885811-3	2021	The phase solubility profiles were all classified as AL-type that indicated the 1:1 stoichiometric relationship with the stability constants Ks which were 22 M-1 (alpha-CD), 612 M-1 (beta-CD), and 14,410 M-1 (gamma-CD), respectively.	Potassium	141-143	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	183-190
34838148-3	2021	RESULTS: There were positive correlation between potassium level with miR-34 (p  = 0.008, r  = 0.366), miR-148 (p  = 0.004, r  = 0.394) and miR-155 (p  = 0.031, r  = 0.300).	Potassium	49-58	microRNA 155	Homo sapiens	140-147
34826216-14	2021	Reactive astrocytes have reduced Kir 4.1-mediated currents, which would impair their ability to buffer potassium.	Potassium	103-112	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	33-40
34976304-9	2021	Tyrosine kinase inhibitors (TKIs), including imatinib and nilotinib, have a non-specific target, namely plateletderived growth factor receptor (PDGFR), which indirectly affects blood potassium and calcium levels in CML patients.	Potassium	183-192	platelet derived growth factor receptor beta	Homo sapiens	104-142
34976304-9	2021	Tyrosine kinase inhibitors (TKIs), including imatinib and nilotinib, have a non-specific target, namely plateletderived growth factor receptor (PDGFR), which indirectly affects blood potassium and calcium levels in CML patients.	Potassium	183-192	platelet derived growth factor receptor beta	Homo sapiens	144-149
34899793-7	2021	In pldalpha1-1 plants, higher accumulation of abscisic and jasmonic acid (JA) and impaired magnesium, potassium and phosphate homeostasis were observed under high-Mg2+ conditions.	Potassium	102-111	phospholipase D alpha 1	Arabidopsis thaliana	3-14
34826216-16	2021	These deficits in potassium and glutamate handling by astrocytes could exacerbate seizures in SCN8A epileptic encephalopathy.	Potassium	18-27	sodium channel, voltage-gated, type VIII, alpha	Mus musculus	94-99
34946993-4	2021	Ppz1 is a negative effector of potassium influx.	Potassium	31-40	salt homeostasis regulator	Saccharomyces cerevisiae S288C	0-4
34799448-8	2021	CUL3 depletion phenocopies Tango10 mutant effects on PDF even in the absence of the core clock gene timeless Patch clamp electrophysiology in Tango10 mutant neurons demonstrates elevated spontaneous firing potentially due to reduced voltage-gated Shaker-like potassium currents.	Potassium	259-268	cullin 3	Homo sapiens	0-4
34835850-4	2021	Electrochemical analysis showed that aminated modification enhanced the peak current intensity of Nafion/GOx-NH2/OMC-COOH (1.32-fold increase), with increases in the charge transfer coefficient alpha (0.54), the apparent electron transfer rate constant ks (2.54 s-1), and the surface coverage Gamma (2.91 x 10-9 mol cm-2).	Potassium	253-255	hydroxyacid oxidase 1	Homo sapiens	105-108
34783023-7	2022	Carriers of FGB rs1800790 A allele and F13 rs5985 T allele had lower Ks , prolonged CLT, and higher ETP compared with major homozygotes (all p<0.05).	Potassium	69-71	fibrinogen beta chain	Homo sapiens	12-15
34798312-10	2022	Finally, we demonstrate that the plant-specific RABA2a-SNARE pathway is essential to maintain potassium homeostasis.	Potassium	94-103	RAB GTPase 11C	Arabidopsis thaliana	48-54
34798312-10	2022	Finally, we demonstrate that the plant-specific RABA2a-SNARE pathway is essential to maintain potassium homeostasis.	Potassium	94-103	small NF90 (ILF3) associated RNA E	Homo sapiens	55-60
34828398-11	2021	This study implicates an important role for KCNG1 as a member of the potassium voltage-gated channel group in neurodegeneration.	Potassium	69-78	potassium voltage-gated channel modifier subfamily G member 1	Bos taurus	44-49
34766906-3	2021	Enhanced spiking was dependent on ATP-sensitive potassium (KATP) channels formed with KCNJ11 and ABCC8 subunits, which we show are functionally expressed in most neocortical neuronal types.	Potassium	48-57	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	86-92
34766906-3	2021	Enhanced spiking was dependent on ATP-sensitive potassium (KATP) channels formed with KCNJ11 and ABCC8 subunits, which we show are functionally expressed in most neocortical neuronal types.	Potassium	48-57	ATP binding cassette subfamily C member 8	Homo sapiens	97-102
34782852-6	2021	The RELA international inter-laboratory comparisons of potassium in serum in 2018 conducted by our laboratory also yielded a satisfactory result.	Potassium	55-64	RELA proto-oncogene, NF-kB subunit	Homo sapiens	4-8
34545966-5	2021	The monopotassium reagent reacts with one or half an equivalent of B 2 (NMe 2 ) 2 Cl 2 to afford NDP-based diboranes with three or four amino substituents.	Potassium	4-17	immunoglobulin kappa variable 5-2	Homo sapiens	67-86
34633813-7	2021	On the other hand, SPC/E+J/C model is most consistent (67%) with the experimental potassium binding sites, followed by OPC+J/C (60%), TIP3P+J/C (53%), and OPC+L/M HFE (27%).	Potassium	82-91	surfactant protein C	Homo sapiens	19-22
34725152-8	2021	Furthermore, miR-127-3p reconstitution in a KS xenograft mouse model suppresses KSHV-positive tumor growth by targeting SKP2 in vivo.	Potassium	44-46	S-phase kinase associated protein 2	Homo sapiens	120-124
34725152-9	2021	These findings identify a previously unrecognized tumor suppressor function for miR-127-3p in KS and demonstrate that the miR-127-3p/SKP2 axis is a viable therapeutic strategy for KS.	Potassium	180-182	microRNA 1273a	Homo sapiens	122-132
34806040-1	2021	We have recently demonstrated that the activity of hexokinase 2 is dependent on the intracellular potassium ion (K+) concentration ((K+)).	Potassium	98-111	hexokinase 2	Homo sapiens	51-63
34764684-6	2021	Results: On adjustment for traditional risk factors (age, BMI, ALB, ALK, ASP, calcium, cholesterol, potassium, sodium, total protein, uric acid), SHBG could be regarded as an independent predictor for BMD, while fasting blood glucose did not.	Potassium	100-109	sex hormone binding globulin	Homo sapiens	146-150
34171450-9	2021	IL-10 was negatively associated with BUN (r = -0.39,p = 0.07), creatinine (r = -0.35, p = 0.002), sodium (r = -0.45, p = 0.03), and potassium (r = -0.68, p = 0.003).	Potassium	132-141	interleukin 10	Homo sapiens	0-5
34795560-2	2021	Dynamic regulation of Kv4.2 protein interactions adapts the transient potassium current, IA, mediated by Kv4 alpha-subunits.	Potassium	70-79	potassium voltage-gated channel subfamily D member 2	Homo sapiens	22-27
34597788-5	2021	Everybody agrees upon the fact that SGLT2is are different from other classical diuretics (thiazides and loop diuretics) as they present some favourable properties, i.e. reduced sympathetic activity, preserved potassium balance, lower risk of acute renal injury, decrease of serum uric acid level.	Potassium	209-218	solute carrier family 5 member 2	Homo sapiens	36-41
34539838-3	2021	The present study aimed to investigate the effect and molecular mechanism of TNF-alpha on the basolateral inwardly rectifying potassium (Kir)4.1/Kir5.1 channels in the thick ascending limb (TAL) of rat kidneys using western blotting and the patch clamp technique to provide a theoretical basis for the cause of the decrease in kidney concentrating capacity during diabetes.	Potassium	126-135	tumor necrosis factor	Rattus norvegicus	77-86
34539838-3	2021	The present study aimed to investigate the effect and molecular mechanism of TNF-alpha on the basolateral inwardly rectifying potassium (Kir)4.1/Kir5.1 channels in the thick ascending limb (TAL) of rat kidneys using western blotting and the patch clamp technique to provide a theoretical basis for the cause of the decrease in kidney concentrating capacity during diabetes.	Potassium	126-135	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	137-144
34539838-3	2021	The present study aimed to investigate the effect and molecular mechanism of TNF-alpha on the basolateral inwardly rectifying potassium (Kir)4.1/Kir5.1 channels in the thick ascending limb (TAL) of rat kidneys using western blotting and the patch clamp technique to provide a theoretical basis for the cause of the decrease in kidney concentrating capacity during diabetes.	Potassium	126-135	potassium inwardly-rectifying channel, subfamily J, member 16	Rattus norvegicus	145-151
34171450-12	2021	TNF-alpha demonstrated positive association with creatinine (r = 0.4,p = 0.006), BUN (r = 0.63,p = 0.003), sodium (r = 0.44, p = 0.04), potassium (r = 0.41, p = 0.04), and was negatively associated with RVFAC (r = -0.38,p = 0.03) and 6MWT distance (r = -0.54, p = 0.004).	Potassium	136-145	tumor necrosis factor	Homo sapiens	0-9
34736759-1	2021	INTRODUCTION: Drug-induced block of the hERG potassium channel could predispose to torsade de pointes, depending on occurrence of concomitant blocks of the calcium and/or sodium channels.	Potassium	45-54	ETS transcription factor ERG	Homo sapiens	40-44
34658111-3	2021	Sodium/potassium ATPase (Na+ K+ -ATPase) is a membrane-bound signaling protein that induces capacitation in bull sperm in response to the steroid hormone ouabain, and its subunit isoforms alpha1, alpha3, beta1, beta2, and beta3 are known in HPM.	Potassium	7-16	glycoprotein hormone subunit alpha 2	Homo sapiens	211-216
34213071-0	2021	Spectroscopic analysis of coenzyme binding to betaine aldehyde dehydrogenase dependent of potassium.	Potassium	90-99	aldehyde dehydrogenase 7 family member A1	Homo sapiens	46-76
34658111-3	2021	Sodium/potassium ATPase (Na+ K+ -ATPase) is a membrane-bound signaling protein that induces capacitation in bull sperm in response to the steroid hormone ouabain, and its subunit isoforms alpha1, alpha3, beta1, beta2, and beta3 are known in HPM.	Potassium	7-16	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3	Homo sapiens	222-227
34656860-4	2021	Here we show that NPF6.2/NRT1.4, a protein that gates nitrate accumulation at the leaf petiole of Arabidopsis thaliana, also affects the root/shoot distribution of potassium.	Potassium	164-173	Major facilitator superfamily protein	Arabidopsis thaliana	18-24
34762363-13	2021	Mice subjected to 14 days of potassium-deficient diet developed polyuria and AQP2 downregulation in IM.	Potassium	29-38	aquaporin 2	Mus musculus	77-81
34656860-5	2021	We demonstrate that NPF6.2/NRT1.4 is a plasma membrane nitrate transporter phosphorylated at threonine-98 by the CIPK23 protein kinase that is a regulatory hub for nitrogen and potassium nutrition.	Potassium	177-186	Major facilitator superfamily protein	Arabidopsis thaliana	20-26
34656860-5	2021	We demonstrate that NPF6.2/NRT1.4 is a plasma membrane nitrate transporter phosphorylated at threonine-98 by the CIPK23 protein kinase that is a regulatory hub for nitrogen and potassium nutrition.	Potassium	177-186	CBL-interacting protein kinase 23	Arabidopsis thaliana	113-119
34686334-7	2021	Our data indicate that p38 regulates cell volumes through the sodium-potassium-chloride cotransporter NKCC1.	Potassium	69-78	p38b MAP kinase	Drosophila melanogaster	23-26
34873512-7	2021	As her ketonemia resolved, she was initiated on subcutaneous insulin with a small but acceptable decrease in potassium.	Potassium	109-118	insulin	Homo sapiens	61-68
34833037-3	2021	Since hyperactivity of motoneurons and muscle spasticity after spinal cord injury are associated with KCC2 downregulation, we hypothesized that a decrease in potassium (K+)/chloride (Cl-) co-transporter 2 (KCC2) in motoneurons would be responsible for an increase in soleus muscle EMG activity during HS.	Potassium	158-167	solute carrier family 12 member 5	Rattus norvegicus	206-210
34698632-4	2021	PTCH1 depletes accessible cholesterol in the outer leaflet of the membrane in a manner regulated by its ligand Sonic Hedgehog and the transmembrane potassium gradient.	Potassium	148-157	patched 1	Homo sapiens	0-5
34698632-5	2021	We propose that PTCH1 moves cholesterol from the outer to the inner leaflet of the membrane in exchange for potassium ion export.	Potassium	108-117	patched 1	Homo sapiens	16-21
34686554-11	2021	By multivariable regression, on average, liver cirrhosis was associated with a reduced potassium lowering effect of 0.42 mmol/L (95% CI 0.22 to 0.63 mmol/L, p<0.001) from insulin-glucose treatment, after adjusting for age, serum creatinine, cancer, pretreatment potassium level, beta-blocker use and cotreatments (sodium polystyrene sulfonate, salbutamol, sodium bicarbonate).	Potassium	87-96	insulin	Homo sapiens	171-178
34686554-11	2021	By multivariable regression, on average, liver cirrhosis was associated with a reduced potassium lowering effect of 0.42 mmol/L (95% CI 0.22 to 0.63 mmol/L, p<0.001) from insulin-glucose treatment, after adjusting for age, serum creatinine, cancer, pretreatment potassium level, beta-blocker use and cotreatments (sodium polystyrene sulfonate, salbutamol, sodium bicarbonate).	Potassium	262-271	insulin	Homo sapiens	171-178
34586799-4	2021	Herein, we report the high-resolution NMR structure of a ternary complex of berberine bound to the dGMP-fill-in PDGFR-beta vG4 in potassium solution.	Potassium	130-139	platelet derived growth factor receptor alpha	Homo sapiens	112-122
34649698-11	2021	ERS-related SCN5A-G452C did not alter the inward sodium current (INa) when SCN5A was expressed alone, but when coexpressed with KCND3 it reduced peak INa by 44.52% and increased the transient outward potassium current (Ito) by 106.81%.	Potassium	200-209	sodium voltage-gated channel alpha subunit 5	Homo sapiens	12-17
34649698-11	2021	ERS-related SCN5A-G452C did not alter the inward sodium current (INa) when SCN5A was expressed alone, but when coexpressed with KCND3 it reduced peak INa by 44.52% and increased the transient outward potassium current (Ito) by 106.81%.	Potassium	200-209	sodium voltage-gated channel alpha subunit 5	Homo sapiens	75-80
34649698-11	2021	ERS-related SCN5A-G452C did not alter the inward sodium current (INa) when SCN5A was expressed alone, but when coexpressed with KCND3 it reduced peak INa by 44.52% and increased the transient outward potassium current (Ito) by 106.81%.	Potassium	200-209	potassium voltage-gated channel subfamily D member 3	Homo sapiens	128-133
34633458-2	2022	Here we provide insights into uncoupling this tight control by specifically targeting the expression of TINY ROOT HAIR 1 (TRH1), a member of plant HAK/KUP/KT transporters that facilitate potassium uptake by co-transporting protons, in Arabidopsis root cell files.	Potassium	187-196	Potassium transporter family protein	Arabidopsis thaliana	104-120
34633458-2	2022	Here we provide insights into uncoupling this tight control by specifically targeting the expression of TINY ROOT HAIR 1 (TRH1), a member of plant HAK/KUP/KT transporters that facilitate potassium uptake by co-transporting protons, in Arabidopsis root cell files.	Potassium	187-196	Potassium transporter family protein	Arabidopsis thaliana	122-126
34692745-6	2021	In the group receiving PN under the supervision of a surgeon, the level of blood glucose (207 vs. 182, P < 0.01), sodium (138 vs. 136, P = 0.01), potassium (3.97 vs. 3.53, P < 0.01), and white blood cell count (9.83 vs. 9.28, P < 0.01) increased significantly at the end of the PN compared to baseline.	Potassium	146-155	U6 snRNA biogenesis phosphodiesterase 1	Homo sapiens	23-25
34534331-6	2021	We explain this directionality in terms of two factors: (i) the preference of hPOT1-TPP1 for the binding site situated at the 3" end of a telomeric sequence and (ii) the cooperative binding displayed by hPOT1-TPP1 in potassium.	Potassium	217-226	protection of telomeres 1	Homo sapiens	78-83
34534331-6	2021	We explain this directionality in terms of two factors: (i) the preference of hPOT1-TPP1 for the binding site situated at the 3" end of a telomeric sequence and (ii) the cooperative binding displayed by hPOT1-TPP1 in potassium.	Potassium	217-226	tripeptidyl peptidase 1	Homo sapiens	84-88
34534331-6	2021	We explain this directionality in terms of two factors: (i) the preference of hPOT1-TPP1 for the binding site situated at the 3" end of a telomeric sequence and (ii) the cooperative binding displayed by hPOT1-TPP1 in potassium.	Potassium	217-226	protection of telomeres 1	Homo sapiens	203-208
34534331-6	2021	We explain this directionality in terms of two factors: (i) the preference of hPOT1-TPP1 for the binding site situated at the 3" end of a telomeric sequence and (ii) the cooperative binding displayed by hPOT1-TPP1 in potassium.	Potassium	217-226	tripeptidyl peptidase 1	Homo sapiens	209-213
34619679-6	2022	In THP-1 cells, beta-TCP increased also IL-18 production, and NLRP3 inflammasome activation by beta-TCP depended on phagocytosis, potassium efflux, and reactive oxygen species (ROS) generation.	Potassium	130-139	NLR family pyrin domain containing 3	Homo sapiens	62-67
34692745-6	2021	In the group receiving PN under the supervision of a surgeon, the level of blood glucose (207 vs. 182, P < 0.01), sodium (138 vs. 136, P = 0.01), potassium (3.97 vs. 3.53, P < 0.01), and white blood cell count (9.83 vs. 9.28, P < 0.01) increased significantly at the end of the PN compared to baseline.	Potassium	146-155	U6 snRNA biogenesis phosphodiesterase 1	Homo sapiens	278-280
34746693-5	2021	Potassium efflux through SLO2.1 hyperpolarizes the membrane.	Potassium	0-9	potassium sodium-activated channel subfamily T member 2	Homo sapiens	25-31
34477710-4	2021	Here we explore the roles of atmospheric water and carbon dioxide in mediating the transformation of the tetrahedrally coordinated potassium aluminate dimer salt (K2Al2O(OH)6) to gibbsite versus potassium dawsonite (KAl(CO3)(OH)2).	Potassium	195-204	anosmin 1	Homo sapiens	216-219
34641523-9	2021	These proteins are involved in the binding of nucleic acids (GBG10, RT24, RALYL), in the organization of proteasomes and nucleosomes (PSA4, NP1L4), and participate in the functioning of the channel of active potassium transport (KCNE5, KCNV2).	Potassium	208-217	RALY RNA binding protein like	Homo sapiens	74-79
34641523-9	2021	These proteins are involved in the binding of nucleic acids (GBG10, RT24, RALYL), in the organization of proteasomes and nucleosomes (PSA4, NP1L4), and participate in the functioning of the channel of active potassium transport (KCNE5, KCNV2).	Potassium	208-217	potassium voltage-gated channel subfamily E regulatory subunit 5	Homo sapiens	229-234
34641523-9	2021	These proteins are involved in the binding of nucleic acids (GBG10, RT24, RALYL), in the organization of proteasomes and nucleosomes (PSA4, NP1L4), and participate in the functioning of the channel of active potassium transport (KCNE5, KCNV2).	Potassium	208-217	potassium voltage-gated channel modifier subfamily V member 2	Homo sapiens	236-241
34680484-0	2021	Effective Perturbations on the Amplitude and Hysteresis of Erg-Mediated Potassium Current Caused by 1-Octylnonyl 8-((2-hydroxyethyl)(6-oxo-6(undecyloxy)hexyl)amino)-octanoate (SM-102), a Cationic Lipid.	Potassium	72-81	ETS transcription factor	Mus musculus	59-62
34597356-5	2022	Using intravenous (IV) insulin to shift potassium intracellularly may cause hypoglycemia, requiring additional treatment or longer hospitalization.	Potassium	40-49	insulin	Homo sapiens	23-30
34597356-14	2022	CONCLUSION: Administration of reduced-dose IV insulin for treatment of hyperkalemia was significantly less effective in lowering serum potassium levels and did not decrease prevalence of hypoglycemia.	Potassium	135-144	insulin	Homo sapiens	46-53
34387857-7	2021	The data suggest that Pellino-2 is essential for mediating the effect of potassium efflux on inflammasome activation.	Potassium	73-82	pellino E3 ubiquitin protein ligase family member 2	Homo sapiens	22-31
34358615-10	2021	However, we measured a marked inhibition (85-90%) of potassium-stimulated DA release in the striatum of Slc39a14-KO mice relative to WT.	Potassium	53-62	solute carrier family 39 (zinc transporter), member 14	Mus musculus	104-112
34387857-6	2021	The co-localization and inflammasome activation were abrogated by several potassium channel inhibitors, supporting a role for potassium efflux in modulating intracellular localization of Pellino-2.	Potassium	126-135	pellino E3 ubiquitin protein ligase family member 2	Homo sapiens	187-196
34192362-0	2021	MYB77 regulates high-affinity potassium uptake by promoting expression of HAK5.	Potassium	30-39	myb domain protein 77	Arabidopsis thaliana	0-5
34252449-7	2021	Long-term potassium homeostasis was maintained in CnB1-KO mice, but in-vivo and ex-vivo experiments indicated that CnB1 contributes to acute regulation of potassium balance and sodium chloride-cotransporter.	Potassium	155-164	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	Mus musculus	115-119
34192362-0	2021	MYB77 regulates high-affinity potassium uptake by promoting expression of HAK5.	Potassium	30-39	high affinity K+ transporter 5	Arabidopsis thaliana	74-78
34638858-5	2021	TMEM175 was more permeable to cesium than potassium ions, voltage-dependently blocked by 4-aminopyridine (4-AP), and slightly inhibited by extracellular acidification.	Potassium	42-51	transmembrane protein 175	Mus musculus	0-7
34665521-3	2021	Previous studies on freshly isolated cortical collecting ducts (CCD) demonstrated that exogenous NO promotes basolateral potassium (K+ ) conductance through basolateral channels, presumably Kir 4.1 (Kcnj10) and Kir 5.1 (Kcnj16).	Potassium	121-130	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	190-197
34665521-3	2021	Previous studies on freshly isolated cortical collecting ducts (CCD) demonstrated that exogenous NO promotes basolateral potassium (K+ ) conductance through basolateral channels, presumably Kir 4.1 (Kcnj10) and Kir 5.1 (Kcnj16).	Potassium	121-130	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	211-218
34665521-3	2021	Previous studies on freshly isolated cortical collecting ducts (CCD) demonstrated that exogenous NO promotes basolateral potassium (K+ ) conductance through basolateral channels, presumably Kir 4.1 (Kcnj10) and Kir 5.1 (Kcnj16).	Potassium	121-130	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	220-226
34684456-0	2021	Association of Sodium, Potassium and Sodium-to-Potassium Ratio with Urine Albumin Excretion among the General Chinese Population.	Potassium	23-32	albumin	Homo sapiens	74-81
34684456-0	2021	Association of Sodium, Potassium and Sodium-to-Potassium Ratio with Urine Albumin Excretion among the General Chinese Population.	Potassium	47-56	albumin	Homo sapiens	74-81
34582479-2	2021	It is caused by mutations in TMEM38B encoding for the trimeric intracellular cation channel TRIC-B, specific for potassium and ubiquitously present in the endoplasmic reticulum (ER) membrane.	Potassium	113-122	transmembrane protein 38B	Homo sapiens	29-36
34463641-2	2021	KCNJ5 mutations contribute to a loss of potassium selectivity and an inward Na+ current could be detected in cells transfected with mutated KCNJ5.	Potassium	40-49	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	0-5
34463641-2	2021	KCNJ5 mutations contribute to a loss of potassium selectivity and an inward Na+ current could be detected in cells transfected with mutated KCNJ5.	Potassium	40-49	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	140-145
34582479-2	2021	It is caused by mutations in TMEM38B encoding for the trimeric intracellular cation channel TRIC-B, specific for potassium and ubiquitously present in the endoplasmic reticulum (ER) membrane.	Potassium	113-122	transmembrane protein 38B	Homo sapiens	92-98
34631800-9	2021	Serum potassium level was significantly lower in the abnormal beta-catenin staining group.	Potassium	6-15	catenin beta 1	Homo sapiens	62-74
34638578-1	2021	Inwardly rectifying Kir4.1 channels in astrocytes mediate spatial potassium (K+) buffering, a clearance mechanism for excessive extracellular K+, in tripartite synapses.	Potassium	66-75	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	20-26
34631800-7	2021	Adjusted CYP11B2 H-score was correlated with serum aldosterone, aldosterone to renin ratio (ARR), and serum potassium.	Potassium	108-117	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	9-16
34549350-7	2021	Finally, we experimentally validate our top-scoring de novo mutation NP_001243143.1:p.Phe309Ser in the sodium/potassium-transporting ATPase ATP1A3 to disrupt protein binding with different partners.	Potassium	110-119	ATPase Na+/K+ transporting subunit alpha 3	Homo sapiens	140-146
34630093-12	2021	Mechanically, FGF21 can ameliorate the electrophysiological function of AC16 cells, which is characterized by rescuing the expression and dysfunction of cardiac sodium current (I Na) and inward rectifier potassium (I k1) in AC16 cells induced by hydrogen peroxide.	Potassium	204-213	fibroblast growth factor 21	Homo sapiens	14-19
34630137-3	2021	Urinary sodium, potassium, and chloride concentrations as well as urinary osmolality were lower in hAAT-Tg mice maintained on a high salt diet during both the active and inactive cycles.	Potassium	16-25	serpin family A member 1	Homo sapiens	99-103
34524838-0	2021	Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.	Potassium	26-35	NLR family pyrin domain containing 3	Homo sapiens	39-44
34664888-2	2021	Systemic pro-inflammatory cytokines released from synovial tissues in rheumatoid arthritis, such as interleukin (IL)-1beta, IL-6, and tumor necrosis factor-alpha, could have direct effects on cardiac electrophysiology, particularly changes in the expression and function of potassium and calcium channels, resulting in QT interval prolongation on surface electrocardiogram (ECG) and an increased predisposition to develop lethal ventricular arrhythmias.	Potassium	274-283	interleukin 1 alpha	Homo sapiens	100-122
34535765-4	2021	We showed that immature IQSEC2 mutant dentate gyrus (DG) granule neurons were extremely hyperexcitable, exhibiting increased sodium and potassium currents compared to those of CRISPR-Cas9-corrected isogenic controls, and displayed dysregulation of genes involved in differentiation and development.	Potassium	136-145	IQ motif and Sec7 domain ArfGEF 2	Homo sapiens	24-30
34664888-2	2021	Systemic pro-inflammatory cytokines released from synovial tissues in rheumatoid arthritis, such as interleukin (IL)-1beta, IL-6, and tumor necrosis factor-alpha, could have direct effects on cardiac electrophysiology, particularly changes in the expression and function of potassium and calcium channels, resulting in QT interval prolongation on surface electrocardiogram (ECG) and an increased predisposition to develop lethal ventricular arrhythmias.	Potassium	274-283	interleukin 6	Homo sapiens	124-128
34664888-2	2021	Systemic pro-inflammatory cytokines released from synovial tissues in rheumatoid arthritis, such as interleukin (IL)-1beta, IL-6, and tumor necrosis factor-alpha, could have direct effects on cardiac electrophysiology, particularly changes in the expression and function of potassium and calcium channels, resulting in QT interval prolongation on surface electrocardiogram (ECG) and an increased predisposition to develop lethal ventricular arrhythmias.	Potassium	274-283	tumor necrosis factor	Homo sapiens	134-161
34603048-3	2021	The etiology of ionic imbalances resulting from stroke-induced ischemia and acidosis includes the dysregulation of multiple plasma membrane transport proteins, such as increased activity of sodium-potassium-chloride cotransporter-1 (NKCC-1).	Potassium	197-206	solute carrier family 12 member 2	Homo sapiens	233-239
34506016-14	2022	In the training set, correlation analysis showed that CK19 expression was correlated with preoperative potassium (P value(P) = 0.030), satellite nodules (P < 0.001) and microvascular invasion (P = 0.020).	Potassium	103-112	keratin 19	Homo sapiens	54-58
34506016-16	2022	Univariate Cox regression correlation analyses showed that CK19 expression was correlated with preoperative potassium (P value(P) = 0.030), satellite nodules (P < 0.001), and microvascular invasion (P = 0.020).	Potassium	108-117	keratin 19	Homo sapiens	59-63
34499251-3	2022	Our objective was to investigate if plasma renin activity and serum aldosterone are associated with urine sodium and potassium in youth referred for hypertensive disorders.	Potassium	117-126	renin	Homo sapiens	43-48
34873451-6	2021	A combined fluorescence potassium ion assay with three channel modulators (4-aminopyridine, emodin-Orf3a channel blocker, and gliclazide-E channel blocker) was developed to detect SARS-CoV-2 Orf3a/E channel activity.	Potassium	24-33	ORF3a protein	Severe acute respiratory syndrome coronavirus 2	191-198
34499251-6	2022	We used multivariable generalized linear models to estimate the associations of renin and aldosterone with urine sodium and potassium.	Potassium	124-133	renin	Homo sapiens	80-85
34522111-0	2021	Effect of Angiotensin Receptor Blocker and Angiotensin Converting Enzyme Inhibitor on Kidney Function and Blood Potassium Level in Indonesian Type 2 Diabetes Mellitus with Hypertension: A Three-Month Cohort Study.	Potassium	112-121	angiotensin I converting enzyme	Homo sapiens	43-72
34483253-4	2021	The DLM was trained using 12 ECG leads (lead I, II, III, aVR, aVL, aVF, and V1-6) to detect patients with serum potassium concentrations <3.5 mmol/L and was validated using retrospective data from the Jiangling branch of the Second Affiliated Hospital of Nanchang University.	Potassium	112-121	immunoglobulin kappa variable 1-5	Homo sapiens	76-80
34459253-1	2021	Background Pathogenic variation in the ATP1A3-encoded sodium-potassium ATPase, ATP1A3, is responsible for alternating hemiplegia of childhood (AHC).	Potassium	61-70	ATPase Na+/K+ transporting subunit alpha 3	Homo sapiens	39-45
34459253-1	2021	Background Pathogenic variation in the ATP1A3-encoded sodium-potassium ATPase, ATP1A3, is responsible for alternating hemiplegia of childhood (AHC).	Potassium	61-70	ATPase Na+/K+ transporting subunit alpha 3	Homo sapiens	79-85
34479475-2	2021	KCNQ4 plays an important role in the cochlear potassium circulation and outer hair cells survival.	Potassium	46-55	potassium voltage-gated channel, subfamily Q, member 4	Mus musculus	0-5
34385153-0	2021	Reciprocal changes in voltage-gated potassium and subthreshold inward currents help maintain firing dynamics of AVPV kisspeptin neurons during the estrous cycle.	Potassium	36-45	KiSS-1 metastasis-suppressor	Mus musculus	117-127
34385153-14	2021	We found voltage-dependent potassium currents in AVPV kisspeptin neurons change with phase of the estrous cycle.	Potassium	27-36	KiSS-1 metastasis-suppressor	Mus musculus	54-64
34333245-0	2021	The expression of constitutively active CPK3 impairs potassium uptake and transport in Arabidopsis under low K+ stress.	Potassium	53-62	calcium-dependent protein kinase 6	Arabidopsis thaliana	40-44
34333245-13	2021	Overall, the data reported here demonstrate that the expression of constitutively active of CPK3 impairs potassium uptake and transports in Arabidopsis under low K+ stress by inhibiting the activity of AKT1.	Potassium	105-114	calcium-dependent protein kinase 6	Arabidopsis thaliana	92-96
34333245-13	2021	Overall, the data reported here demonstrate that the expression of constitutively active of CPK3 impairs potassium uptake and transports in Arabidopsis under low K+ stress by inhibiting the activity of AKT1.	Potassium	105-114	K+ transporter 1	Arabidopsis thaliana	202-206
34363606-10	2021	SGLT2 inhibitors can minimally increase potassium levels, but this has not been shown by the CREDENCE trial.	Potassium	40-49	solute carrier family 5 member 2	Homo sapiens	0-5
34125902-6	2021	Fourth, we examined physiological characteristics of GnRH (mCh-hESC) neurons: Similar to GnRH neurons in vivo, they released the GnRH peptide in a pulsatile manner at ~60 min intervals, GnRH release increased in response to high potassium, kisspeptin, estradiol and neurokinin B challenges, and injection of depolarizing current induced action potentials.	Potassium	229-238	gonadotropin releasing hormone 1	Homo sapiens	186-190
34373707-2	2021	The imbalance of the retinal microenvironment and destruction of the blood-retinal barrier have a significant role in the progression of DR. Inward rectifying potassium channel 4.1 (Kir4.1) is located on Muller cells and is closely related to potassium homeostasis, water balance and glutamate clearance in the whole retina.	Potassium	243-252	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	182-188
34091989-8	2021	In the overweight/obese group, the serum AhR level had a negative correlation with potassium, coffee and alcohol consumption and a positive correlation with suprailiac skinfold thickness.	Potassium	83-92	aryl hydrocarbon receptor	Homo sapiens	41-44
34495934-2	2021	Extended-release (ER) potassium chloride is designed for postpyloric release rather than colonic absorption and is postulated to be an appropriate option for potassium repletion in this patient subset.	Potassium	158-167	epiregulin	Homo sapiens	0-16
34294377-3	2021	Analyses of the steady-state I-V relationships implied that the depolarizing effect of NTS is due to potassium conductance blocking.	Potassium	101-110	neurotensin	Rattus norvegicus	87-90
34294377-5	2021	In the presence of a CaMKII inhibitor, NTS showed depolarizing effects via the increase in non-selective cation conductance in addition to the decrease in potassium conductance.	Potassium	155-164	neurotensin	Rattus norvegicus	39-42
34471138-6	2021	We show that microglia-node interaction is modulated by neuronal activity and associated potassium release, with THIK-1 ensuring their microglial read-out.	Potassium	89-98	potassium two pore domain channel subfamily K member 13	Homo sapiens	113-119
34330444-5	2021	Herein, a nanobiosensor for detecting sodium and potassium ions using folic acid-functionalised reduced graphene oxide-modified RNase A gold nanoclusters (FA-rGO-RNase A/AuNCs) based on fluorescence "turn-off/turn-on" is presented.	Potassium	49-58	ribonuclease A family member 1, pancreatic	Homo sapiens	128-135
34392451-10	2021	While the furin is hijacked by the virus, the decreased activity of ENaC would be expected, which causes retention of potassium ions and hyperkalemia.	Potassium	118-127	furin, paired basic amino acid cleaving enzyme	Homo sapiens	10-15
34484804-6	2021	Relevance and novel information: PHP in Burmese cats has been well described, but all cases to date have been shown to be secondary to a genetic mutation in WNK4, resulting in potassium wasting into the urine.	Potassium	176-185	WNK lysine deficient protein kinase 4	Felis catus	157-161
34330444-5	2021	Herein, a nanobiosensor for detecting sodium and potassium ions using folic acid-functionalised reduced graphene oxide-modified RNase A gold nanoclusters (FA-rGO-RNase A/AuNCs) based on fluorescence "turn-off/turn-on" is presented.	Potassium	49-58	ribonuclease A family member 1, pancreatic	Homo sapiens	162-169
34330444-9	2021	Finally, a fluorescence "turn-on" sensing strategy is developed using the as-synthesised FA-rGO-RNase A/AuNCs to detect sodium and potassium ions.	Potassium	131-140	ribonuclease A family member 1, pancreatic	Homo sapiens	96-103
34440230-8	2021	Whole-cell patch-clamp data revealed that mutated KCNJ5 157-159delITE channel exhibited loss of potassium ion selectivity.	Potassium	96-105	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	50-55
34424803-15	2022	The median potassium concentration decrease post-Digoxin-Fab was 0.3 mmol/L.	Potassium	11-20	FA complementation group B	Homo sapiens	57-60
34349235-10	2022	Furthermore, in cardiomyocytes, ISO increased the efflux of potassium and the generation of ROS, which are recognized as activators of the NLRP3 inflammasome.	Potassium	60-69	NLR family, pyrin domain containing 3	Mus musculus	139-144
34539987-1	2021	Downregulation of inward rectifier potassium (IK1) channel is a hallmark in cardiac hypertrophy and failure.	Potassium	35-44	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	46-49
34100078-8	2021	The interaction between the GPCRs and MLC1 was dynamically regulated upon changes in the osmolarity or potassium concentration.	Potassium	103-112	megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)	Mus musculus	38-42
34395179-3	2021	Our multi-approach study, based on the combination of structural experimental data and quantum-chemical DFT calculations, led to identify a sequestration site for sodium, potassium and chloride ions within the central cavity of both the SARS-CoV-1 and SARS-CoV-2 spike proteins.	Potassium	171-180	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	263-268
34348722-12	2021	OGTT showed that her glucose metabolism and insulin resistance much improved after potassium and magnesium supplemental therapy.	Potassium	83-92	insulin	Homo sapiens	44-51
34458695-2	2021	Using ex vivo blood vessels and primary endothelial cells from human brain microvessels, we show that patient-derived Abeta assemblies, termed amylospheroids (ASPD), exist on the microvascular surface in patients" brains and inhibit vasorelaxation through binding to the alpha3 subunit of sodium, potassium-ATPase (NAKalpha3) in caveolae on endothelial cells.	Potassium	297-306	amyloid beta precursor protein	Homo sapiens	118-123
34421636-6	2021	R MAX to potassium, NA, and PHE were lower in HA-NBSH when compared with LA-NBSH and potency results were similar.	Potassium	9-18	protein max	Ovis aries	2-5
34260214-3	2021	For 107 countries, we analyze the colocation of human-derived nutrients (in urine) and crop demands for nitrogen, phosphorus, and potassium.	Potassium	130-139	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	87-91
34341510-2	2022	TWIK2 potassium channel mediates potassium efflux that has been reported to be an essential upstream mechanism for ATP-induced NLRP3 inflammasome activation.	Potassium	33-42	potassium inwardly-rectifying channel, subfamily K, member 6	Mus musculus	0-5
34341510-2	2022	TWIK2 potassium channel mediates potassium efflux that has been reported to be an essential upstream mechanism for ATP-induced NLRP3 inflammasome activation.	Potassium	33-42	NLR family, pyrin domain containing 3	Mus musculus	127-132
34361012-8	2021	Electrophysiological investigation, however, demonstrated that the KV4.3 p.R419H variant was associated with a dominant increase in potassium current amplitudes, as well as notable changes in voltage-dependent gating properties leading to enhanced potassium window current.	Potassium	132-141	potassium voltage-gated channel subfamily D member 3	Homo sapiens	67-74
34288161-0	2021	Ti3 C2 Tx MXene Conductive Layers Supported Bio-Derived Fex -1 Sex /MXene/Carbonaceous Nanoribbons for High-Performance Half/Full Sodium-Ion and Potassium-Ion Batteries.	Potassium	145-154	stabilin 1	Homo sapiens	56-62
34288161-2	2021	In this work, a novel Fex -1 Sex heterostructure is prepared on fungus-derived carbon matrix encapsulated by 2D Ti3 C2 Tx MXene highly conductive layers, which exhibits high specific sodium ion (Na+ ) and potassium ion (K+ ) storage capacities of 610.9 and 449.3 mAh g-1 at a current density of 0.1 A g-1 , respectively, and excellent capacity retention at high charge-discharge rates.	Potassium	205-214	stabilin 1	Homo sapiens	22-28
34290105-5	2021	betagamma-CAT targeted acidic glycosphingolipids on the HSV type 1 (HSV-1) envelope to induce pore formation, as indicated by the oligomer formation of protein and potassium and calcium ion efflux.	Potassium	164-173	catalase	Homo sapiens	10-13
34334139-5	2021	These actions of sodium, potassium and magnesium and other minerals, trace elements and vitamins are likely to be secondary to their action on pro-inflammatory cytokines IL-6, TNF-alpha and IL-17 and metabolism of essential fatty acids that may account for their involvement in the pathobiology of insulin resistance, T2DM, HTN and autoimmune diseases.	Potassium	25-34	interleukin 6	Homo sapiens	170-174
34334139-5	2021	These actions of sodium, potassium and magnesium and other minerals, trace elements and vitamins are likely to be secondary to their action on pro-inflammatory cytokines IL-6, TNF-alpha and IL-17 and metabolism of essential fatty acids that may account for their involvement in the pathobiology of insulin resistance, T2DM, HTN and autoimmune diseases.	Potassium	25-34	tumor necrosis factor	Homo sapiens	176-185
34334139-5	2021	These actions of sodium, potassium and magnesium and other minerals, trace elements and vitamins are likely to be secondary to their action on pro-inflammatory cytokines IL-6, TNF-alpha and IL-17 and metabolism of essential fatty acids that may account for their involvement in the pathobiology of insulin resistance, T2DM, HTN and autoimmune diseases.	Potassium	25-34	interleukin 17A	Homo sapiens	190-195
34334139-5	2021	These actions of sodium, potassium and magnesium and other minerals, trace elements and vitamins are likely to be secondary to their action on pro-inflammatory cytokines IL-6, TNF-alpha and IL-17 and metabolism of essential fatty acids that may account for their involvement in the pathobiology of insulin resistance, T2DM, HTN and autoimmune diseases.	Potassium	25-34	insulin	Homo sapiens	298-305
34142217-0	2021	Hydrogen sulfide (H2S) and potassium (K+) synergistically induce drought stress tolerance through regulation of H+-ATPase activity, sugar metabolism, and antioxidative defense in tomato seedlings.	Potassium	27-36	plasma membrane ATPase 1	Solanum lycopersicum	112-121
34142217-1	2021	KEY MESSAGE: Exogenous potassium (K+) and endogenous hydrogen sulfide (H2S) synergistically alleviate drought stress through regulating H+-ATPase activity, sugar metabolism and redox homoeostasis in tomato seedlings.	Potassium	23-32	plasma membrane ATPase 1	Solanum lycopersicum	136-145
34361012-8	2021	Electrophysiological investigation, however, demonstrated that the KV4.3 p.R419H variant was associated with a dominant increase in potassium current amplitudes, as well as notable changes in voltage-dependent gating properties leading to enhanced potassium window current.	Potassium	248-257	potassium voltage-gated channel subfamily D member 3	Homo sapiens	67-74
34491898-0	2021	Sodium-Glucose Cotransporter-2 Inhibitors and the Risk of Abnormal Serum Potassium Level.	Potassium	73-82	solute carrier family 5 member 2	Homo sapiens	0-30
34314446-6	2021	In our model, the key effect of gain of function FHM-3 mutations is ion fluxes modification at each action potential (in particular the larger activation of voltage-gated potassium channels induced by the NaV1.1 gain of function), and the resulting CSD-triggering extracellular potassium accumulation, which is not caused only by modifications of firing frequency.	Potassium	278-287	sodium voltage-gated channel alpha subunit 1	Homo sapiens	49-54
34314446-6	2021	In our model, the key effect of gain of function FHM-3 mutations is ion fluxes modification at each action potential (in particular the larger activation of voltage-gated potassium channels induced by the NaV1.1 gain of function), and the resulting CSD-triggering extracellular potassium accumulation, which is not caused only by modifications of firing frequency.	Potassium	278-287	sodium voltage-gated channel alpha subunit 1	Homo sapiens	205-211
34314446-8	2021	Our modeling results connect qualitatively to experimental data: potassium accumulation in the case of FHM-3 mutations and facilitated depolarization block of the GABAergic neuron in the case of epileptogenic mutations.	Potassium	65-74	sodium voltage-gated channel alpha subunit 1	Homo sapiens	103-108
34135001-0	2021	Gonadotropin-releasing hormone (GnRH) neuron potassium currents and excitability in both sexes exhibit minimal changes upon removal of negative feedback.	Potassium	45-54	gonadotropin releasing hormone 1	Mus musculus	0-30
34135001-0	2021	Gonadotropin-releasing hormone (GnRH) neuron potassium currents and excitability in both sexes exhibit minimal changes upon removal of negative feedback.	Potassium	45-54	gonadotropin releasing hormone 1	Mus musculus	32-36
34227466-7	2021	We propose that neuronal activation and an extracellular increase in potassium suppress calcium activity in CPs, likely mediated by Kir2.2 and KATP channels.	Potassium	69-78	potassium inwardly-rectifying channel, subfamily J, member 12	Mus musculus	132-138
34085706-3	2021	The human voltage-gated potassium (hKV ) channel hKV 7.2/7.3 is a validated antiseizure target for compounds that activate this channel.	Potassium	24-33	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	49-60
34180110-9	2021	He-CTD of the (M + 2Na)2+ and the (M + 2 K)2+ precursors generated singly charged product ions from the loss of a sodium ion and potassium ion, respectively.	Potassium	129-138	CTD	Homo sapiens	3-6
34140667-6	2021	The data reveal that potassium and chloride fluxes in the thylakoid lumen determined by the K+/H+ antiporter KEA3 and the voltage-gated Cl- channel VCCN1/Best1 have distinct kinetic responses that lead to characteristic and light-intensity-dependent Deltapsi/DeltapH oscillations.	Potassium	21-30	bestrophin 1	Homo sapiens	154-159
34316170-4	2021	This study is the first of its kind to estimate urinary potassium (UrK) excretion and its association with AKI in an Indian intensive care unit (ICU).	Potassium	56-65	plasminogen activator, urokinase	Homo sapiens	67-70
34105352-0	2021	Local Structures of Soft Carbon and Electrochemical Performance of Potassium-Ion Batteries.	Potassium	67-76	POC1 centriolar protein A	Homo sapiens	20-24
34105352-7	2021	Our results show that the potassium storage behavior, especially the potential plateau is closely correlated to non-uniformity in interlayer distance and defect concentration in soft carbon, which is further confirmed by reverse Monte Carlo (RMC) modeling and density functional theory calculation.	Potassium	26-35	POC1 centriolar protein A	Homo sapiens	178-182
34127616-7	2021	Western blots were run from testosterone treated postnatal day 7 animals to measure levels of chloride cotransporters sodium-potassium-chloride symporter (NKCC1) and chloride-potassium symporter 5 (KCC2).	Potassium	125-134	solute carrier family 12 member 2	Rattus norvegicus	155-160
34167889-2	2022	One treatment approach includes intravenous (IV) insulin to shift potassium intracellularly.	Potassium	66-75	insulin	Homo sapiens	49-56
34167889-10	2022	However, lower insulin doses provide a similar potassium-lowering effect and cause a meaningful decrease in hypoglycaemic episodes.	Potassium	47-56	insulin	Homo sapiens	15-22
34127616-7	2021	Western blots were run from testosterone treated postnatal day 7 animals to measure levels of chloride cotransporters sodium-potassium-chloride symporter (NKCC1) and chloride-potassium symporter 5 (KCC2).	Potassium	175-184	solute carrier family 12 member 5	Rattus norvegicus	198-202
34179047-2	2021	We aimed to evaluate renal tubular sodium (Na+) or potassium (K+) associated transporters expression from uEVs and kidney tissues in patients with Gitelman syndrome (GS) caused by inactivating mutations in SLC12A3.	Potassium	51-60	solute carrier family 12 member 3	Homo sapiens	206-213
34814506-9	2021	The sodium-potassium ratio was negatively correlated with age, female and junior high school education or above annual family income (P<0.05), and positively correlated with perceived salty taste, SBP and eating out 3-5 d/week (P<0.05).	Potassium	11-20	selenium binding protein 1	Homo sapiens	197-200
34113239-1	2021	Background Our aim was to investigate the effects of the protein expression and the function of sodium, potassium, and chloride co-transporter (NKCC1) in the dorsal root ganglion (DRG) after activation of transient receptor potential vanilloid 1 receptor (TRPV1) in capsaicin-induced acute inflammatory pain and the possible mechanism of action.	Potassium	104-113	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	205-254
34081759-4	2021	KS conjugate 1 with rather stable construct was more potent in tumor growth inhibition that might be explained by the CD13 receptor recognition of NGR sequence.	Potassium	0-2	alanyl (membrane) aminopeptidase	Mus musculus	118-122
34081759-4	2021	KS conjugate 1 with rather stable construct was more potent in tumor growth inhibition that might be explained by the CD13 receptor recognition of NGR sequence.	Potassium	0-2	reticulon 4 receptor	Mus musculus	147-150
33909880-15	2021	CONCLUSIONS: Isoflurane increased an outwardly rectifying potassium current in ventral horn neurons of the Ndufs4(KO) mouse at a concentration much lower than in controls.	Potassium	58-67	NADH:ubiquinone oxidoreductase core subunit S4	Mus musculus	107-113
34205849-2	2021	Kir5.1 is an inwardly-rectifying potassium (Kir) channel with high sensitivity to intracellular H+ (pHi) and extracellular K+ concentration (K+)o, and hence provides a link between pHi and (K+)o changes and membrane potential.	Potassium	33-42	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	0-6
34205849-2	2021	Kir5.1 is an inwardly-rectifying potassium (Kir) channel with high sensitivity to intracellular H+ (pHi) and extracellular K+ concentration (K+)o, and hence provides a link between pHi and (K+)o changes and membrane potential.	Potassium	33-42	glucose-6-phosphate isomerase 1	Mus musculus	100-103
34205849-2	2021	Kir5.1 is an inwardly-rectifying potassium (Kir) channel with high sensitivity to intracellular H+ (pHi) and extracellular K+ concentration (K+)o, and hence provides a link between pHi and (K+)o changes and membrane potential.	Potassium	33-42	glucose-6-phosphate isomerase 1	Mus musculus	181-184
34170815-0	2021	Minority potassium-uptake system Trk2 has a crucial role in yeast survival of glucose-induced cell death.	Potassium	9-18	Trk2p	Saccharomyces cerevisiae S288C	33-37
34170815-3	2021	S. cerevisiae cells possess two transporters, Trk1 and Trk2, which ensure a high intracellular concentration of potassium, necessary for many physiological processes.	Potassium	112-121	Trk1p	Saccharomyces cerevisiae S288C	46-50
34170815-3	2021	S. cerevisiae cells possess two transporters, Trk1 and Trk2, which ensure a high intracellular concentration of potassium, necessary for many physiological processes.	Potassium	112-121	Trk2p	Saccharomyces cerevisiae S288C	55-59
34170815-4	2021	Trk1 is the major system responsible for potassium acquisition in growing and dividing cells.	Potassium	41-50	Trk1p	Saccharomyces cerevisiae S288C	0-4
34170815-5	2021	The contribution of Trk2 to potassium uptake in growing cells is almost negligible, but Trk2 becomes crucial for stationary cells for their survival of some stresses, e.g. anhydrobiosis.	Potassium	28-37	Trk2p	Saccharomyces cerevisiae S288C	20-24
34170815-7	2021	Our results also demonstrate that Trk2 is much more important for the cell survival of glucose-induced cell death than Trk1, and that stationary cells deficient in active potassium uptake lose their ATP stocks more rapidly than cells with functional Trk systems.	Potassium	171-180	Trk2p	Saccharomyces cerevisiae S288C	34-38
34170815-7	2021	Our results also demonstrate that Trk2 is much more important for the cell survival of glucose-induced cell death than Trk1, and that stationary cells deficient in active potassium uptake lose their ATP stocks more rapidly than cells with functional Trk systems.	Potassium	171-180	Trk1p	Saccharomyces cerevisiae S288C	119-123
34170815-8	2021	This is probably due to the upregulated activity of plasma-membrane Pma1 H+-ATPase, and consequently, it is the reason why these cells die earlier than cells with functional active potassium uptake.	Potassium	181-190	H(+)-exporting P2-type ATPase PMA1	Saccharomyces cerevisiae S288C	68-72
34113239-1	2021	Background Our aim was to investigate the effects of the protein expression and the function of sodium, potassium, and chloride co-transporter (NKCC1) in the dorsal root ganglion (DRG) after activation of transient receptor potential vanilloid 1 receptor (TRPV1) in capsaicin-induced acute inflammatory pain and the possible mechanism of action.	Potassium	104-113	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	256-261
34065270-7	2021	However, when the calcium and/or potassium minerals were removed from DOW, the effects of reduction of triglyceride level, inhibition of acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and peroxisome proliferator-activated receptor-alpha (PPAR-alpha) expressions, and activation of superoxide dismutase, catalase, and glutathione reductase activities would be weaker.	Potassium	33-42	fatty acid synthase	Mus musculus	167-186
34072275-0	2021	Neuropeptide S Receptor Stimulation Excites Principal Neurons in Murine Basolateral Amygdala through a Calcium-Dependent Decrease in Membrane Potassium Conductance.	Potassium	142-151	neuropeptide S receptor 1	Mus musculus	0-23
34072275-6	2021	The NPSR1-mediated current had a reversal potential near the potassium reversal potential (EK) and was accompanied by an increase in membrane input resistance.	Potassium	61-70	neuropeptide S receptor 1	Mus musculus	4-9
34065270-7	2021	However, when the calcium and/or potassium minerals were removed from DOW, the effects of reduction of triglyceride level, inhibition of acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and peroxisome proliferator-activated receptor-alpha (PPAR-alpha) expressions, and activation of superoxide dismutase, catalase, and glutathione reductase activities would be weaker.	Potassium	33-42	fatty acid synthase	Mus musculus	188-191
34065270-7	2021	However, when the calcium and/or potassium minerals were removed from DOW, the effects of reduction of triglyceride level, inhibition of acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and peroxisome proliferator-activated receptor-alpha (PPAR-alpha) expressions, and activation of superoxide dismutase, catalase, and glutathione reductase activities would be weaker.	Potassium	33-42	peroxisome proliferator activated receptor alpha	Mus musculus	198-246
34065270-7	2021	However, when the calcium and/or potassium minerals were removed from DOW, the effects of reduction of triglyceride level, inhibition of acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and peroxisome proliferator-activated receptor-alpha (PPAR-alpha) expressions, and activation of superoxide dismutase, catalase, and glutathione reductase activities would be weaker.	Potassium	33-42	peroxisome proliferator activated receptor alpha	Mus musculus	248-258
34064873-3	2021	The mechanism of action of CG"s toxicity is inhibition of Na+/K+-ATPase (the sodium-potassium pump, NKA), which disrupts the ionic homeostasis leading to elevated Ca2+ concentration resulting in cell death.	Potassium	84-93	NKA	Bos taurus	100-103
34484992-3	2021	A potassium-competitive acid blocker (P-CAB), vonoprazan (VPZ), was recently introduced, which may provide clinical benefits.	Potassium	2-11	neural proliferation, differentiation and control 1	Homo sapiens	40-43
34554906-4	2021	The aim of this study was to screen genetic alterations in regions coding for calcium (cav1.1), sodium (nav1.4), and potassium (Kir2.6) channels, evaluating its impact on the phenotype of patients with THPP.	Potassium	117-126	potassium inwardly rectifying channel subfamily J member 18	Homo sapiens	128-134
34792000-10	2021	Ang-(1-7) attenuated the increased urinary flow and the fractional excretion of H2O and potassium observed in GM rats but intensified the elevated excretion of sodium in these animals.	Potassium	88-97	angiogenin	Rattus norvegicus	0-8
34568829-9	2021	Additionally, dilations to elevated extracellular potassium and BaCl2- or ML 133-induced constrictions in pressurized arteries were significantly decreased following TBI, consistent with an impairment of Kir2.1 channel function.	Potassium	50-59	potassium inwardly-rectifying channel, subfamily J, member 2	Rattus norvegicus	204-210
35089322-7	2022	Furthermore, potassium depolarization elicited cytoplasmic calcium transients in cells in which WT CaV1.1 was replaced with the calcium impermeant mutant CaV1.1(N617D), indicating that JPH1, JPH2, and JPH3 can all support voltage-induced calcium release, despite sequence divergence and differences in interaction with RYR1.	Potassium	13-22	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	99-105
35089322-7	2022	Furthermore, potassium depolarization elicited cytoplasmic calcium transients in cells in which WT CaV1.1 was replaced with the calcium impermeant mutant CaV1.1(N617D), indicating that JPH1, JPH2, and JPH3 can all support voltage-induced calcium release, despite sequence divergence and differences in interaction with RYR1.	Potassium	13-22	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	154-160
35089322-7	2022	Furthermore, potassium depolarization elicited cytoplasmic calcium transients in cells in which WT CaV1.1 was replaced with the calcium impermeant mutant CaV1.1(N617D), indicating that JPH1, JPH2, and JPH3 can all support voltage-induced calcium release, despite sequence divergence and differences in interaction with RYR1.	Potassium	13-22	junctophilin 1	Homo sapiens	185-189
35089322-7	2022	Furthermore, potassium depolarization elicited cytoplasmic calcium transients in cells in which WT CaV1.1 was replaced with the calcium impermeant mutant CaV1.1(N617D), indicating that JPH1, JPH2, and JPH3 can all support voltage-induced calcium release, despite sequence divergence and differences in interaction with RYR1.	Potassium	13-22	junctophilin 2	Homo sapiens	191-195
35089322-7	2022	Furthermore, potassium depolarization elicited cytoplasmic calcium transients in cells in which WT CaV1.1 was replaced with the calcium impermeant mutant CaV1.1(N617D), indicating that JPH1, JPH2, and JPH3 can all support voltage-induced calcium release, despite sequence divergence and differences in interaction with RYR1.	Potassium	13-22	junctophilin 3	Homo sapiens	201-205
35089322-7	2022	Furthermore, potassium depolarization elicited cytoplasmic calcium transients in cells in which WT CaV1.1 was replaced with the calcium impermeant mutant CaV1.1(N617D), indicating that JPH1, JPH2, and JPH3 can all support voltage-induced calcium release, despite sequence divergence and differences in interaction with RYR1.	Potassium	13-22	ryanodine receptor 1	Homo sapiens	319-323
35500463-0	2022	A wearable electrochemical sensor based on beta-CD functionalized graphene for pH and potassium ion analysis in sweat.	Potassium	86-95	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	43-50
35353387-3	2022	A commonly reported mechanism contributing to NLRP3 inflammasome activation is potassium ion (K+ ) efflux across the plasma membrane.	Potassium	79-88	NLR family, pyrin domain containing 3	Mus musculus	46-51
35604136-0	2022	Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.	Potassium	32-41	ATPase H+/K+ transporting subunit alpha	Homo sapiens	83-94
35248639-2	2022	Based on the soil sampling and survey data set, this study established the path analysis model of SANs (soil available nutrients, including ammonium nitrogen (AN), available phosphorus (AP) and available potassium (AK)) with topography, climate and vegetation in order to explore how environmental factors interact to affect the content of SANs.	Potassium	204-213	USH1 protein network component sans	Homo sapiens	98-102
35505467-1	2022	BACKGROUND: Keverprazan is a novel potassium-competitive acid blocker (P-CAB) with a strong acid-suppressive capacity that may provide clinical benefit in acid-related diseases.	Potassium	35-44	neural proliferation, differentiation and control 1	Homo sapiens	73-76
35189160-10	2022	Furthermore, CATH-2-mediated IL-1beta secretion and caspase-1 activation is dependent on potassium efflux but independent of P2X7R.	Potassium	89-98	cathelicidin-2	Gallus gallus	13-19
35319903-4	2022	Importantly, ERK1/2 was reported to inhibit the transient outward potassium current (IA) in hippocampal neurons.	Potassium	66-75	mitogen activated protein kinase 3	Rattus norvegicus	13-19
35189160-10	2022	Furthermore, CATH-2-mediated IL-1beta secretion and caspase-1 activation is dependent on potassium efflux but independent of P2X7R.	Potassium	89-98	interleukin 1 alpha	Mus musculus	29-37
35189160-10	2022	Furthermore, CATH-2-mediated IL-1beta secretion and caspase-1 activation is dependent on potassium efflux but independent of P2X7R.	Potassium	89-98	caspase 1	Gallus gallus	52-61
35290476-11	2022	To identify a molecular basis for this crosstalk, we screened for renal transcription factors that were downregulated in the Ks-Glut2 KO mice.	Potassium	125-127	solute carrier family 2 (facilitated glucose transporter), member 2	Mus musculus	128-133
35194770-4	2022	Glucose- and potassium-stimulated insulin secretion assays were performed to assess beta-cell function.	Potassium	13-22	insulin	Homo sapiens	34-41
35098342-10	2022	On the contrary, the amplitude of the volume-activated potassium current is lower in CF HBDC, suggesting the potassium channel density or open probability is decreased in CF cholangiocytes and/or CFTR may have regulatory effects on volume-activated potassium current.	Potassium	55-64	CF transmembrane conductance regulator	Homo sapiens	196-200
35621709-4	2022	Both heterozygous and homozygous Klhl3W523X /+ KI mice exhibited typical PHAII with low-renin hypertension, hyperkalemia with reduced renal potassium excretion, and hyperchloremic metabolic acidosis.	Potassium	140-149	kelch-like 3	Mus musculus	33-38
35098342-10	2022	On the contrary, the amplitude of the volume-activated potassium current is lower in CF HBDC, suggesting the potassium channel density or open probability is decreased in CF cholangiocytes and/or CFTR may have regulatory effects on volume-activated potassium current.	Potassium	249-258	CF transmembrane conductance regulator	Homo sapiens	196-200
35614393-2	2022	However, the impact of the effluent potassium (eK+) concentration on PRHK has been largely overlooked.	Potassium	36-45	choline kinase alpha	Homo sapiens	47-49
35626730-6	2022	Patch-clamp recordings in sensory neurons and in a HEK cell line transfected with TRPA1 and Slack revealed that Slack-dependent potassium currents (IKS) are modulated in a TRPA1-dependent manner.	Potassium	128-137	transient receptor potential cation channel, subfamily A, member 1	Mus musculus	82-87
35619089-18	2022	Potassium levels were positively correlated with PR interval (r=0.283, p=0.038), QRS duration (r=0.361, p=0.003), peaked T wave (r=0.242, p=0.041), and serum levels of creatinine (r=0.347, p=0.004), BUN (r=0.312, p=0.008), and CK (r=0.373, p=0.039).	Potassium	0-9	cytidine/uridine monophosphate kinase 1	Homo sapiens	227-229
35587369-2	2022	We investigated whether and how potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1), a long noncoding RNA, regulates osteoclast differentiation.	Potassium	32-41	KCNQ1 overlapping transcript 1	Mus musculus	111-119
35590402-9	2022	For hip arthroscopy, decrease of potassium levels was observed in 40.8% of the patients, and postoperative hypokalemia was found in 10.2% patients.	Potassium	33-42	hedgehog interacting protein	Homo sapiens	4-7
35589790-3	2022	AVL fires unusual compound action potentials with each depolarizing calcium spike mediated by UNC-2 followed by a hyperpolarizing potassium spike mediated by a repolarization-activated potassium channel EXP-2.	Potassium	130-139	Uncharacterized protein	Caenorhabditis elegans	203-208
35626730-6	2022	Patch-clamp recordings in sensory neurons and in a HEK cell line transfected with TRPA1 and Slack revealed that Slack-dependent potassium currents (IKS) are modulated in a TRPA1-dependent manner.	Potassium	128-137	transient receptor potential cation channel, subfamily A, member 1	Mus musculus	172-177
35570209-4	2022	Specifically, we discovered that knockout of the inwardly rectifying potassium channels Kir4.2 and Kir5.1 (encoded by KCNJ15 and KCNJ16, respectively) rescued polymyxin-induced toxicity in HK-2 cells.	Potassium	69-78	potassium inwardly rectifying channel subfamily J member 15	Homo sapiens	88-94
35578361-7	2022	The usage of infusion of glucose-insulin-potassium in rice tablet poisoning has been suggested, after its positive beneficial cardiac inotropic effects in patients with beta-blocker and calcium channel blocker poisoning.	Potassium	41-50	insulin	Homo sapiens	33-40
35578361-9	2022	In contrast to our previous experiences, in which nearly all patients with critical aluminum phosphide poisoning died, this patient was saved with glucose-insulin-potassium.	Potassium	163-172	insulin	Homo sapiens	155-162
35570209-4	2022	Specifically, we discovered that knockout of the inwardly rectifying potassium channels Kir4.2 and Kir5.1 (encoded by KCNJ15 and KCNJ16, respectively) rescued polymyxin-induced toxicity in HK-2 cells.	Potassium	69-78	potassium inwardly rectifying channel subfamily J member 16	Homo sapiens	99-105
35570209-4	2022	Specifically, we discovered that knockout of the inwardly rectifying potassium channels Kir4.2 and Kir5.1 (encoded by KCNJ15 and KCNJ16, respectively) rescued polymyxin-induced toxicity in HK-2 cells.	Potassium	69-78	potassium inwardly rectifying channel subfamily J member 15	Homo sapiens	118-124
35570209-4	2022	Specifically, we discovered that knockout of the inwardly rectifying potassium channels Kir4.2 and Kir5.1 (encoded by KCNJ15 and KCNJ16, respectively) rescued polymyxin-induced toxicity in HK-2 cells.	Potassium	69-78	potassium inwardly rectifying channel subfamily J member 16	Homo sapiens	129-135
35570209-6	2022	All-atom molecular dynamics simulations revealed that polymyxin B1 spontaneously bound to Kir4.2, thereby increasing opening of the channel, resulting in a potassium influx, and changes of the membrane potential.	Potassium	156-165	potassium inwardly rectifying channel subfamily J member 15	Homo sapiens	90-96
35545295-0	2022	OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection.	Potassium	51-60	oxidative stress responsive kinase 1	Homo sapiens	0-5
35620041-1	2022	Introduction and importance: HHPP is a rare type of hypokalemic PP that can occur when there is hyperthyroidism.Thyrotoxic periodic paralysis is due to increased influx of potassium into skeletal muscle cells which leads to profound hypokalemia and paralysis.	Potassium	172-181	HHPP	Homo sapiens	29-33
35561107-1	2022	Efficient allocation of the essential nutrient potassium (K+ ) is a central determinant of plant ion homeostasis and involves AKT2 K+ channels.	Potassium	47-56	AKT serine/threonine kinase 2	Homo sapiens	126-130
35627493-4	2022	In the whole group of 96 children, active renin concentration correlated positively with serum potassium and office and ambulatory systolic and diastolic blood pressures.	Potassium	95-104	renin	Homo sapiens	42-47
35627493-8	2022	We concluded that active renin concentration is positively associated with blood pressure and potassium in children, and diastolic blood pressure was the strongest predictor of renin level.	Potassium	94-103	renin	Homo sapiens	25-30
35545295-3	2022	Here, we use Mycobacterium marinum infection of zebrafish embryos and Mycobacterium tuberculosis infection of THP-1 cells to demonstrate that pathogenic mycobacteria up-regulate the host WNK signalling pathway kinases SPAK and OXSR1 which control intracellular potassium balance.	Potassium	261-270	serine/threonine kinase 39	Homo sapiens	218-222
35545295-3	2022	Here, we use Mycobacterium marinum infection of zebrafish embryos and Mycobacterium tuberculosis infection of THP-1 cells to demonstrate that pathogenic mycobacteria up-regulate the host WNK signalling pathway kinases SPAK and OXSR1 which control intracellular potassium balance.	Potassium	261-270	oxidative stress responsive kinase 1	Homo sapiens	227-232
35545295-4	2022	We show that genetic depletion or inhibition of OXSR1 decreases bacterial burden and intracellular potassium levels.	Potassium	99-108	oxidative stress responsive kinase 1	Homo sapiens	48-53
35439802-2	2022	Benefiting from the coordination roles of carboxyl and amino groups, and the diffusion role of potassium ions, NTAK could enhance the bilateral connection, improve perovskite morphology, suppress non-radiation recombination, and reduce the hysteresis effect.	Potassium	95-104	neuregulin 2	Homo sapiens	111-115
35394821-4	2022	Methods: A meta-analysis was conducted using individual participant data from randomized, double-blind, placebo-controlled clinical outcome trials with SGLT2 inhibitors in people with type 2 diabetes at high cardiovascular risk and/or with CKD, in which serum potassium levels were routinely measured.	Potassium	260-269	solute carrier family 5 member 2	Homo sapiens	152-157
35510566-3	2022	We found that WHIRLY1 interacts with HDA15, a Reduced Potassium Dependence3 (RPD3) /Histone Deacetylase1 (HDA1)-type histone deacetylase, by using GFP-nanotrap-mass spectrum assays.	Potassium	54-63	ssDNA-binding transcriptional regulator	Arabidopsis thaliana	14-21
35510566-3	2022	We found that WHIRLY1 interacts with HDA15, a Reduced Potassium Dependence3 (RPD3) /Histone Deacetylase1 (HDA1)-type histone deacetylase, by using GFP-nanotrap-mass spectrum assays.	Potassium	54-63	histone deacetylase 15	Arabidopsis thaliana	37-42
35510566-3	2022	We found that WHIRLY1 interacts with HDA15, a Reduced Potassium Dependence3 (RPD3) /Histone Deacetylase1 (HDA1)-type histone deacetylase, by using GFP-nanotrap-mass spectrum assays.	Potassium	54-63	histone deacetylase 1	Arabidopsis thaliana	106-110
35508186-1	2022	Sympathetic regulation of the Kv4.2 transient outward potassium current is critical for the acute electrical and contractile response of the myocardium under physiological and pathological conditions.	Potassium	54-63	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	30-35
35601308-1	2022	Biomass combustion equipment is often susceptible to ash deposition due to the relatively significant quantities of potassium, silicon, and other ash-forming elements in biomass.	Potassium	116-125	arylsulfatase family member H	Homo sapiens	53-56
35245523-8	2022	In contrast, angiotensin II decreased the expression (64-97% reduction in band density) of sodium-hydrogen exchanger-3 (NHE3), NHE regulatory factor-1 (NHERF1, Slc9a3r1), sodium-potassium-2-chloride cotransporter (NKCC2), and epithelial sodium channel (ENaC) beta- and gamma- subunits in the renal cortex of both WT and PPAR-alpha KO mice, with no difference between genotypes.	Potassium	178-187	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	120-124
35508541-0	2022	The dopamine transporter antiports potassium to increase the uptake of dopamine.	Potassium	35-44	Dopamine transporter	Drosophila melanogaster	4-24
35487592-2	2022	In recent years, it has been indicated that the MR expressed in retinal Muller cells plays an important role in regulating the potassium and water balance in the retina.	Potassium	127-136	nuclear receptor subfamily 3 group C member 2	Homo sapiens	48-50
35629795-2	2022	KCNE3 plays an important role in the recycling of potassium ion by binding with KCNQ1.	Potassium	50-59	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	0-5
35193934-3	2022	In slices from oxycodone treated animals, no tolerance to opioids was observed when measuring the MOR induced increase in potassium conductance but the G protein Receptor Kinase 2/3 (GRK2/3) blocker, compound 101, no longer inhibited desensitization of somatostatin (SST) receptors.	Potassium	122-131	opioid receptor mu 1	Homo sapiens	98-101
35231557-0	2022	Cleavage of Kv2.1 by BACE1 decreases potassium current and reduces neuronal apoptosis.	Potassium	37-46	potassium voltage-gated channel subfamily B member 1	Homo sapiens	12-17
35231557-0	2022	Cleavage of Kv2.1 by BACE1 decreases potassium current and reduces neuronal apoptosis.	Potassium	37-46	beta-secretase 1	Homo sapiens	21-26
35231557-4	2022	Kv2.1, a potassium channel, modulates potassium current in cortical neurons and potassium efflux is a requisite event in the process of cell apoptosis.	Potassium	38-47	potassium voltage-gated channel subfamily B member 1	Homo sapiens	0-5
35231557-4	2022	Kv2.1, a potassium channel, modulates potassium current in cortical neurons and potassium efflux is a requisite event in the process of cell apoptosis.	Potassium	80-89	potassium voltage-gated channel subfamily B member 1	Homo sapiens	0-5
35231557-8	2022	Our work indicates that BACE1 plays a neuroprotective role to reduce potassium efflux by cleavage of Kv2.1, implying inhibition of BACE1 may be neurotoxic.	Potassium	69-78	beta-secretase 1	Homo sapiens	24-29
35231557-8	2022	Our work indicates that BACE1 plays a neuroprotective role to reduce potassium efflux by cleavage of Kv2.1, implying inhibition of BACE1 may be neurotoxic.	Potassium	69-78	potassium voltage-gated channel subfamily B member 1	Homo sapiens	101-106
35231557-8	2022	Our work indicates that BACE1 plays a neuroprotective role to reduce potassium efflux by cleavage of Kv2.1, implying inhibition of BACE1 may be neurotoxic.	Potassium	69-78	beta-secretase 1	Homo sapiens	131-136
35254168-9	2022	Moreover, SVA 3D induces calcium influx and potassium efflux, which triggers IL-1beta secretion.	Potassium	44-53	interleukin 1 alpha	Homo sapiens	77-85
35629795-2	2022	KCNE3 plays an important role in the recycling of potassium ion by binding with KCNQ1.	Potassium	50-59	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	80-85
35548367-3	2022	Although changes in inward rectifier potassium currents including I K1 are known to contribute to the pathogenesis of fibrillation, the effect of sildenafil on I K1 has not been studied.	Potassium	37-46	IKAROS family zinc finger 1	Homo sapiens	66-70
35471735-3	2022	Herein, a liquid metal interfacial engineering strategy is reported for the synthesis of porous carbon using CCl4 as the carbon precursor and sodium-potassium alloy (NaK) as the reducing agent, which is superior to traditional synthetic methods because it enables the engineering of a highly active liquid metal alloy microemulsion to directly generate porous carbon at ambient temperature.	Potassium	149-158	TANK binding kinase 1	Homo sapiens	166-169
35628688-3	2022	Trk1 has been shown to exist in low- or high-affinity modes, which reflect the availability of potassium in the environment.	Potassium	95-104	Trk1p	Saccharomyces cerevisiae S288C	0-4
34983065-6	2022	Similarly, cultured Celsr2 mutant motoneurons extend longer neurites and larger growth cones, with increased expression of end-binding protein 3, and higher potassium-induced calcium influx.	Potassium	157-166	cadherin, EGF LAG seven-pass G-type receptor 2	Mus musculus	20-26
35387601-10	2022	However, for each 500 mg decrement in potassium intake, there was an 11% increase risk of incident CKD (IRR = 1.11, 95% CI = 1.00, 1.24).	Potassium	38-47	insulin receptor related receptor	Homo sapiens	104-107
35573575-1	2022	Hypokalemic periodic paralysis (hypo KPP) is a rare form of autosomal dominant channelopathy characterized by muscular weakness and paralysis caused by decreased potassium levels.	Potassium	162-171	keratin 10	Homo sapiens	37-40
35463019-1	2022	Background: Bartter syndrome (BS) type II is a rare autosomal recessive renal tubular disorder caused by mutations in the KCNJ1 gene, which encodes the apical renal outer medullary potassium (ROMK) channel in the thick ascending limb (TAL) of Henle"s loop.	Potassium	181-190	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	122-127
35463019-1	2022	Background: Bartter syndrome (BS) type II is a rare autosomal recessive renal tubular disorder caused by mutations in the KCNJ1 gene, which encodes the apical renal outer medullary potassium (ROMK) channel in the thick ascending limb (TAL) of Henle"s loop.	Potassium	181-190	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	192-196
35387601-11	2022	Additionally, every 1 M ratio increment of sodium -to -potassium ratio was associated with a 21% increased risk of incident CKD (IRR = 1.21, 95% CI = 1.02, 1.45), p < 0.05).	Potassium	55-64	insulin receptor related receptor	Homo sapiens	129-132
35407326-0	2022	Chemical Vapor Deposition-Fabricated Manganese-Doped and Potassium-Doped Hexagonal Tungsten Trioxide Nanowires with Enhanced Gas Sensing and Photocatalytic Properties.	Potassium	57-66	gastrin	Homo sapiens	125-128
35493109-8	2022	In the striatum, the basal extracellular level of dopamine and potassium-evoked dopamine release decreased significantly in mice lacking CASP8, clearly showing the low dopamine functioning in tissues innervated by this neurotransmitter.	Potassium	63-72	caspase 8	Mus musculus	137-142
35407326-8	2022	Additionally, the gas sensing response for 20 ppm of ethanol showed a positive dependence of doping with the manganese-doped and potassium-doped responses being 14.4% and 29.7%, respectively, higher than the pure response at 250  C. The manganese-doped and potassium-doped tungsten oxide nanowires are attractive candidates in gas sensing, photocatalytic, and energy storage applications, including water splitting, photochromism, and rechargeable batteries.	Potassium	129-138	gastrin	Homo sapiens	327-330
35407326-8	2022	Additionally, the gas sensing response for 20 ppm of ethanol showed a positive dependence of doping with the manganese-doped and potassium-doped responses being 14.4% and 29.7%, respectively, higher than the pure response at 250  C. The manganese-doped and potassium-doped tungsten oxide nanowires are attractive candidates in gas sensing, photocatalytic, and energy storage applications, including water splitting, photochromism, and rechargeable batteries.	Potassium	257-266	gastrin	Homo sapiens	18-21
35407326-8	2022	Additionally, the gas sensing response for 20 ppm of ethanol showed a positive dependence of doping with the manganese-doped and potassium-doped responses being 14.4% and 29.7%, respectively, higher than the pure response at 250  C. The manganese-doped and potassium-doped tungsten oxide nanowires are attractive candidates in gas sensing, photocatalytic, and energy storage applications, including water splitting, photochromism, and rechargeable batteries.	Potassium	129-138	gastrin	Homo sapiens	18-21
35571388-2	2022	Vonoprazan (VPZ), a novel potassium-competitive acid blocker (P-CAB), has been approved in China after demonstrating clinical benefit in RE.	Potassium	26-35	neural proliferation, differentiation and control 1	Homo sapiens	64-67
35178888-8	2022	HDAC3 protein expression was upregulated in mpkCCD and IMCD cells in response to potassium deprivation, and the binding of HDAC3 to the Aqp2 promoter was also increased.	Potassium	81-90	histone deacetylase 3	Mus musculus	0-5
35178888-12	2022	CONCLUSION: HDAC inhibitors prevented the downregulation of AQP2 induced by potassium deprivation, probably by enhancing H3K27 acetylation.	Potassium	76-85	aquaporin 2	Rattus norvegicus	60-64
35171697-6	2022	Although the precise mechanisms of NLRP3 activation and regulation by these diverse agonists remain unclear, multiple reports indicate that all NLRP3 agonists ultimately lead to a drop in intracellular concentration of potassium (K+ efflux) and chloride (Cl- efflux).	Potassium	219-228	NLR family pyrin domain containing 3	Homo sapiens	35-40
35171697-6	2022	Although the precise mechanisms of NLRP3 activation and regulation by these diverse agonists remain unclear, multiple reports indicate that all NLRP3 agonists ultimately lead to a drop in intracellular concentration of potassium (K+ efflux) and chloride (Cl- efflux).	Potassium	219-228	NLR family pyrin domain containing 3	Homo sapiens	144-149
35363437-3	2022	Here we utilize mu-X-ray fluorescence imaging in combination with rapid freezing to resolve the elemental distribution of phosphorus, sulfur, potassium, and zinc in huntingtin exon-1-mYFP expressing HeLa cells.	Potassium	142-151	huntingtin	Homo sapiens	165-175
34978207-6	2022	Dietary potassium intake was also significantly associated with complement C3 level (beta  =  -.004; 95% CI (-.007, -.001); p = .021).	Potassium	8-17	complement C3	Homo sapiens	64-77
34978207-9	2022	Dietary sodium intake was significantly associated with anti-dsDNA and complement C4 level, while dietary potassium intake was associated with complement C3 level, supporting that dietary sodium and potassium intakes might play a key role in markers related to disease activity in SLE patients.	Potassium	106-115	complement C3	Homo sapiens	143-156
35401866-2	2022	One common observation is that cortical neurons become overexcited with abnormal running of sodium and potassium ions cross membrane in raised body temperature condition, Considering that astrocyte Kir4.1 channel play a critical role in maintaining extracellular homeostasis of ionic concentrations and electrochemical potentials of neurons by fast depletion of extracellular potassium ions, we examined here the potential role of temperature-dependent Kir4.1 channel in astrocytes in causing FS.	Potassium	103-112	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	198-204
35401866-2	2022	One common observation is that cortical neurons become overexcited with abnormal running of sodium and potassium ions cross membrane in raised body temperature condition, Considering that astrocyte Kir4.1 channel play a critical role in maintaining extracellular homeostasis of ionic concentrations and electrochemical potentials of neurons by fast depletion of extracellular potassium ions, we examined here the potential role of temperature-dependent Kir4.1 channel in astrocytes in causing FS.	Potassium	376-385	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	198-204
35401866-5	2022	The numerical experiment demonstrated that the Kir4.1 channel function optimally in the body temperature around 37  C in cleaning "excessive" extracellular potassium ions during neuronal firing process, however, higher temperature deteriorates its cleaning function, while lower temperature slows down its cleaning efficiency.	Potassium	156-165	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	47-53
35433733-0	2022	Agreement of Potassium, Sodium, Glucose, and Hemoglobin Measured by Blood Gas Analyzer With Dry Chemistry Analyzer and Complete Blood Count Analyzer: A Two-Center Retrospective Analysis.	Potassium	13-22	gastrin	Homo sapiens	74-77
35224841-0	2022	Iron Selenide-Based Heterojunction Construction and Defect Engineering for Fast Potassium/Sodium-Ion Storage.	Potassium	80-89	Fas activated serine/threonine kinase	Homo sapiens	75-79
35538757-8	2022	Conclusions The c.676C>T in FERMT1 gene is the most common mutation in KS.The patients are prone to squamous cell carcinoma and mainly attacked at the exposure sites(hand and mouth).	Potassium	71-73	FERM domain containing kindlin 1	Homo sapiens	28-34
35432399-5	2022	Physiological analysis showed that low potassium treatment could promote malondialdehyde (MDA) accumulation and antioxidant enzyme activities such as peroxidase (POD), ascorbate-peroxidase (APX).	Potassium	39-48	peroxidase N1	Nicotiana tabacum	150-160
35583060-1	2022	Objective To identify the effects of interleukin-6 (IL-6) on astrocytes activation, and the regulation of the expression of inwardly rectifying potassium 4.1 (Kir4.1) channels in astrocytes.	Potassium	144-153	interleukin 6	Rattus norvegicus	37-50
35583060-1	2022	Objective To identify the effects of interleukin-6 (IL-6) on astrocytes activation, and the regulation of the expression of inwardly rectifying potassium 4.1 (Kir4.1) channels in astrocytes.	Potassium	144-153	interleukin 6	Rattus norvegicus	52-56
35583060-1	2022	Objective To identify the effects of interleukin-6 (IL-6) on astrocytes activation, and the regulation of the expression of inwardly rectifying potassium 4.1 (Kir4.1) channels in astrocytes.	Potassium	144-153	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	159-165
35432399-5	2022	Physiological analysis showed that low potassium treatment could promote malondialdehyde (MDA) accumulation and antioxidant enzyme activities such as peroxidase (POD), ascorbate-peroxidase (APX).	Potassium	39-48	peroxidase N1	Nicotiana tabacum	162-165
35432399-5	2022	Physiological analysis showed that low potassium treatment could promote malondialdehyde (MDA) accumulation and antioxidant enzyme activities such as peroxidase (POD), ascorbate-peroxidase (APX).	Potassium	39-48	L-ascorbate peroxidase 2, cytosolic	Nicotiana tabacum	168-188
35432399-5	2022	Physiological analysis showed that low potassium treatment could promote malondialdehyde (MDA) accumulation and antioxidant enzyme activities such as peroxidase (POD), ascorbate-peroxidase (APX).	Potassium	39-48	L-ascorbate peroxidase 2, cytosolic	Nicotiana tabacum	190-193
35333652-1	2022	SignificanceCholesterol is one of the main components found in plasma membranes and is involved in lipid-dependent signaling enabled by integral membrane proteins such as inwardly rectifying potassium (Kir) channels.	Potassium	191-200	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	202-205
35348434-7	2022	Also, potassium inwardly rectifying channel subfamily J member 12 (KCNJ12) was identified as a novel target of miR-29c via dual-luciferase reporter assay, quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR), and western blot.	Potassium	6-15	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	67-73
35348434-7	2022	Also, potassium inwardly rectifying channel subfamily J member 12 (KCNJ12) was identified as a novel target of miR-29c via dual-luciferase reporter assay, quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR), and western blot.	Potassium	6-15	microRNA 29c	Homo sapiens	111-118
35371034-6	2022	Next, our work showed that PLO can form pores in the cell membrane, leading to the efflux of potassium (K+), NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated caspase-1 activation, and gasdermin D (GSDMD) cleavage.	Potassium	93-102	NLR family, pyrin domain containing 3	Mus musculus	161-166
35454100-9	2022	Through compartmentalization of sodium and potassium ions, a significant effect of Na+ upon AQP2 water permeability was highlighted as well.	Potassium	43-52	aquaporin 2	Homo sapiens	92-96
35494963-2	2022	As the correction of acidosis and insulin drive potassium intracellularly, measured serum potassium levels decrease and require repletion.	Potassium	48-57	insulin	Homo sapiens	34-41
35494963-2	2022	As the correction of acidosis and insulin drive potassium intracellularly, measured serum potassium levels decrease and require repletion.	Potassium	90-99	insulin	Homo sapiens	34-41
35316226-1	2022	GOALS: The aim was to examine actual health care cost in patients with gastroesophageal reflux disease (GERD) who were initiated on proton pump inhibitor (PPI) or potassium-competitive acid blocker (P-CAB) as first-line therapy in Japanese real-world clinical settings.	Potassium	163-172	neural proliferation, differentiation and control 1	Homo sapiens	201-204
35110381-1	2022	ATP1A1 encodes the alpha1 subunit of the sodium-potassium ATPase, an electrogenic cation pump highly expressed in the nervous system.	Potassium	48-57	ATPase Na+/K+ transporting subunit alpha 1	Homo sapiens	0-6
35110381-1	2022	ATP1A1 encodes the alpha1 subunit of the sodium-potassium ATPase, an electrogenic cation pump highly expressed in the nervous system.	Potassium	48-57	dynein axonemal heavy chain 8	Homo sapiens	58-64
35371034-6	2022	Next, our work showed that PLO can form pores in the cell membrane, leading to the efflux of potassium (K+), NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated caspase-1 activation, and gasdermin D (GSDMD) cleavage.	Potassium	93-102	caspase 1	Mus musculus	190-199
35371034-6	2022	Next, our work showed that PLO can form pores in the cell membrane, leading to the efflux of potassium (K+), NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated caspase-1 activation, and gasdermin D (GSDMD) cleavage.	Potassium	93-102	gasdermin D	Mus musculus	216-227
35424772-0	2022	Significant structural change in human c-Myc promoter G-quadruplex upon peptide binding in potassium.	Potassium	91-100	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	39-44
35424772-8	2022	Our study for the first time provides an expanded overview of significant structural change in human c-Myc promoter G-quadruplex upon peptide binding in potassium.	Potassium	153-162	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	101-106
35268096-6	2022	In addition, the ratio of sodium to potassium (Na/K ratio) was positively associated with the risk of CVD (HR comparing extreme quintiles = 1.26, 95% CI: 1.14-1.39, p trend < 0.0001).	Potassium	36-45	TANK binding kinase 1	Homo sapiens	47-51
35236788-9	2022	Through a literature review, we found 22 patients (including our patient) with CHH due to biallelic PROKR2 variants, which led us to recognize that most of the patients (86%) were diagnosed with KS.	Potassium	195-197	prokineticin receptor 2	Homo sapiens	100-106
35213803-0	2022	In Situ Monitoring of Extracellular K+ Using the Potentiometric Mode of Scanning Electrochemical Microscopy with a Carbon-Based Potassium Ion-Selective Tip.	Potassium	128-137	TOR signaling pathway regulator	Homo sapiens	152-155
35084562-3	2022	Modifications of inward rectifier potassium (Kir) currents including IK1 are known to play an important role in arrhythmogenesis; however, no data on the aminophylline effect on these currents have been published.	Potassium	34-43	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	69-72
34995420-7	2022	RESULTS: Gal-3-treated HL-1 myocytes had a shorter action potential duration, smaller L-type calcium current, increased sarcoplasmic reticulum (SR) calcium content, Na+ /Ca2+ exchanger (NCX) current, transient outward potassium current, and ultrarapid delayed rectifier potassium current than control cells had.	Potassium	218-227	lectin, galactose binding, soluble 3	Mus musculus	9-14
34995420-7	2022	RESULTS: Gal-3-treated HL-1 myocytes had a shorter action potential duration, smaller L-type calcium current, increased sarcoplasmic reticulum (SR) calcium content, Na+ /Ca2+ exchanger (NCX) current, transient outward potassium current, and ultrarapid delayed rectifier potassium current than control cells had.	Potassium	270-279	lectin, galactose binding, soluble 3	Mus musculus	9-14
35134656-5	2022	RESULTS: After adjustment for confounding factors, including statin use, only low-density lipoprotein cholesterol (LDL-C) and apoB levels were inversely associated with Ks.	Potassium	169-171	apolipoprotein B	Homo sapiens	126-130
35058093-4	2022	OBJECTIVE: Describe the incidence of hypoglycemia and relative change in serum potassium when using 5 vs. 10 units of insulin for hyperkalemia in patients with moderate renal dysfunction.	Potassium	79-88	insulin	Homo sapiens	118-125
35058093-20	2022	insulin lowered serum potassium significantly more than 5 units of i.v.	Potassium	22-31	insulin	Homo sapiens	0-7
35177004-5	2022	The functional role of these receptors was examined ex vivo with a capsaicin/potassium induced 5-HT and CGRP release.	Potassium	77-86	calcitonin-related polypeptide alpha	Rattus norvegicus	104-108
35386772-10	2022	When TG levels spiked again, the patient was put on an insulin infusion with heparin, glucose, and potassium to rapidly reduce TG level.	Potassium	99-108	insulin	Homo sapiens	55-62
35199478-0	2022	Reduction in the magnitude of serum potassium elevation in combination therapy with esaxerenone (CS-3150) and sodium-glucose co-transporter-2 inhibitor in patients with diabetic kidney disease: Subanalysis of two phase 3 studies.	Potassium	36-45	solute carrier family 5 member 2	Homo sapiens	110-141
35199478-1	2022	AIMS/INTRODUCTION: We evaluated the effect of co-administration of esaxerenone and a sodium-glucose cotransporter 2 (SGLT2) inhibitor on the magnitude of serum potassium elevation in Japanese patients with diabetic kidney disease.	Potassium	160-169	solute carrier family 5 member 2	Homo sapiens	85-115
35199478-1	2022	AIMS/INTRODUCTION: We evaluated the effect of co-administration of esaxerenone and a sodium-glucose cotransporter 2 (SGLT2) inhibitor on the magnitude of serum potassium elevation in Japanese patients with diabetic kidney disease.	Potassium	160-169	solute carrier family 5 member 2	Homo sapiens	117-122
35199478-4	2022	RESULTS: In both studies, time course changes in serum potassium levels, and incidence rates of serum potassium elevation were lower in patients with co-administration of SGLT2 inhibitor in both the placebo and esaxerenone groups than those without the inhibitor.	Potassium	55-64	solute carrier family 5 member 2	Homo sapiens	171-176
35199478-4	2022	RESULTS: In both studies, time course changes in serum potassium levels, and incidence rates of serum potassium elevation were lower in patients with co-administration of SGLT2 inhibitor in both the placebo and esaxerenone groups than those without the inhibitor.	Potassium	102-111	solute carrier family 5 member 2	Homo sapiens	171-176
35199478-7	2022	CONCLUSIONS: In Japanese patients with type 2 diabetes and albuminuria treated with esaxerenone, concomitant use of SGLT2 inhibitor reduced the magnitude of serum potassium elevation without any change of its antihypertensive and albuminuria-suppressing effects.	Potassium	163-172	solute carrier family 5 member 2	Homo sapiens	116-121
35207588-7	2022	This paper presents three new foci for the hypothesis of life"s origins between mica sheets: (1) that potassium is essential for life"s origins on Earth; (2) that biotite mica has advantages over muscovite mica; and (3) that micaceous clay is a better environment than isolated mica for life"s origins.	Potassium	102-111	MHC class I polypeptide-related sequence A	Homo sapiens	80-84
35207588-7	2022	This paper presents three new foci for the hypothesis of life"s origins between mica sheets: (1) that potassium is essential for life"s origins on Earth; (2) that biotite mica has advantages over muscovite mica; and (3) that micaceous clay is a better environment than isolated mica for life"s origins.	Potassium	102-111	MHC class I polypeptide-related sequence A	Homo sapiens	278-282
35214161-1	2022	Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs).	Potassium	39-48	neural proliferation, differentiation and control 1	Homo sapiens	77-80
35149693-3	2022	Here we show that potassium voltage-gated channel subfamily E regulatory subunits 3 and 4 (KCNE3, KCNE4) are uniquely upregulated at arrhythmia sites within scarred myocardium.	Potassium	18-27	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	91-96
35252186-3	2022	Mechanismly, manoalide inhibited the NLRP3 inflammasome activation by acting downstream of potassium efflux, chloride efflux and mitochondrial dysfunction.	Potassium	91-100	NLR family, pyrin domain containing 3	Mus musculus	37-42
35149693-3	2022	Here we show that potassium voltage-gated channel subfamily E regulatory subunits 3 and 4 (KCNE3, KCNE4) are uniquely upregulated at arrhythmia sites within scarred myocardium.	Potassium	18-27	potassium voltage-gated channel subfamily E regulatory subunit 4	Homo sapiens	98-103
35149693-7	2022	These repolarization heterogeneities are consistent with known functional effects of KCNE3 and KCNE4 on the slow delayed-rectifier potassium current.	Potassium	131-140	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	85-90
35149693-7	2022	These repolarization heterogeneities are consistent with known functional effects of KCNE3 and KCNE4 on the slow delayed-rectifier potassium current.	Potassium	131-140	potassium voltage-gated channel subfamily E regulatory subunit 4	Homo sapiens	95-100
35023510-1	2022	Two-electron reductions of 3,3"-bis(2,6-dimesitylpyridin-4-yl)-1,1"-biphenyl 1 with elemental potassium in the absence and presence of 18-c-6 afforded the diradical dianion salts (K+)2 (trans-1)  2- and (K(18-c-6))+2 (cis-1)  2-, which exhibit trans and cis configurations, respectively.	Potassium	94-103	suppressor of cytokine signaling 1	Homo sapiens	218-223
35205149-8	2022	Surprisingly, Connexin43 also localizes to mitochondria in the cell, playing important roles in mitochondrial potassium import and respiration.	Potassium	110-119	gap junction protein, alpha 1	Mus musculus	14-24
35132967-5	2022	Interestingly, the expression levels of the fast transient outward potassium current-related (Ito,f-related) proteins (Kv4.2, Kv4.3, and KChIP2) in the heart of CKD rats and rats treated with IS decreased.	Potassium	67-76	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	119-124
35132967-5	2022	Interestingly, the expression levels of the fast transient outward potassium current-related (Ito,f-related) proteins (Kv4.2, Kv4.3, and KChIP2) in the heart of CKD rats and rats treated with IS decreased.	Potassium	67-76	potassium voltage-gated channel subfamily D member 3	Rattus norvegicus	126-131
35132967-5	2022	Interestingly, the expression levels of the fast transient outward potassium current-related (Ito,f-related) proteins (Kv4.2, Kv4.3, and KChIP2) in the heart of CKD rats and rats treated with IS decreased.	Potassium	67-76	potassium voltage-gated channel interacting protein 2	Rattus norvegicus	137-143
35204763-6	2022	The iMS-BMAL1 KO mice excreted less potassium during the rest phase during the normal diet but there was no genotype difference during the active phase.	Potassium	36-45	aryl hydrocarbon receptor nuclear translocator-like	Mus musculus	8-13
35018914-1	2022	In contrast to the typical Csp2-H activation, a PN3P-Nickel complex chemoselectively cleaved the benzylic Csp3-H bond of toluene in the presence of KHMDS, presumably via an in situ generated potassium benzyl intermediate.	Potassium	191-200	regulator of calcineurin 2	Homo sapiens	27-31
35072914-12	2022	Another signal is conceivable to be mediated by hazard signals e.g., the purinergic P2X7 receptor stimulated by Adenosine triphosphate or other stimuli resulting in the efflux of potassium.	Potassium	179-188	purinergic receptor P2X 7	Homo sapiens	84-97
35194203-7	2022	Potassium (K+) abundance in the phloem was elevated in sut1 mutant leaves.	Potassium	0-9	sucrose transporter 1	Zea mays	55-59
35224872-2	2022	The early aldosterone-induced sgk1 gene (encoding serum and glucocorticoid-induced kinase 1), activates potassium clearance, but the role of this kinase in the early activation of K+ secretion has not been clearly defined.	Potassium	104-113	serum/glucocorticoid regulated kinase 1	Mus musculus	30-34
35582188-3	2022	Methods: We systematically searched PubMed, EMBASE, CENTRAL, and ClinicalTrials.gov up to January 2021 to identify eligible randomized controlled trials (RCTs) of SGLT2is that reported mean changes in serum electrolytes, including magnesium, sodium, potassium, phosphate, and calcium.	Potassium	250-259	solute carrier family 5 member 2	Homo sapiens	163-168
35042527-10	2022	QT prolongation in Nfx mice was explained by a significant decrease in the fast transient outward potassium (K+) current (Itof), caused by the downregulation of K+ channel 4.2 subunit (Kv4.2) expression.	Potassium	98-107	potassium voltage-gated channel, Shal-related family, member 2	Mus musculus	185-190
35039526-9	2022	The photosynthesis, dry matter accumulation and yield parameters of maize treated with straw returning and deep tillage combined with 60 kg/hm2 potassium fertilizer (SFK60) reached the highest in the three harvest seasons.	Potassium	144-153	Putative anthocyanidin reductase	Zea mays	140-143
35061487-4	2022	We analyze the spin dynamics of helium-3 atoms with hot, optically excited potassium atoms and reveal the formation of quasibound states in resonant binary collisions.	Potassium	75-84	spindlin 1	Homo sapiens	15-19
35045014-11	2022	The messenger Ribonucleic Acid expression of fatty acid desaturase 1 and fatty acid desaturase 2, which are the key enzyme of PUFA metabolism, were lower in KS and keloid-derived fibroblasts, P < 0.05.	Potassium	157-159	fatty acid desaturase 1	Homo sapiens	45-68
35045014-11	2022	The messenger Ribonucleic Acid expression of fatty acid desaturase 1 and fatty acid desaturase 2, which are the key enzyme of PUFA metabolism, were lower in KS and keloid-derived fibroblasts, P < 0.05.	Potassium	157-159	fatty acid desaturase 2	Homo sapiens	73-96
35045014-11	2022	The messenger Ribonucleic Acid expression of fatty acid desaturase 1 and fatty acid desaturase 2, which are the key enzyme of PUFA metabolism, were lower in KS and keloid-derived fibroblasts, P < 0.05.	Potassium	157-159	pumilio RNA binding family member 3	Homo sapiens	126-130
34964963-7	2022	Prediction of protein structure indicated that the variant may affect the potassium ion selective filtration structure channel in the transmembrane region of KCNJ6 protein, which may result in up regulation of the function of the channel.	Potassium	74-83	potassium inwardly rectifying channel subfamily J member 6	Homo sapiens	158-163
35069250-2	2021	Studies in FHHt mice engineered to constitutively activate SPAK specifically in the DCT (CA-SPAK mice) revealed maladaptive remodeling of the aldosterone sensitive distal nephron (ASDN), characterized by decrease in the potassium excretory channel, renal outer medullary potassium (ROMK), and epithelial sodium channel (ENaC), that contributes to the hyperkalemia.	Potassium	220-229	serine/threonine kinase 39	Mus musculus	59-63
35069250-2	2021	Studies in FHHt mice engineered to constitutively activate SPAK specifically in the DCT (CA-SPAK mice) revealed maladaptive remodeling of the aldosterone sensitive distal nephron (ASDN), characterized by decrease in the potassium excretory channel, renal outer medullary potassium (ROMK), and epithelial sodium channel (ENaC), that contributes to the hyperkalemia.	Potassium	271-280	serine/threonine kinase 39	Mus musculus	59-63
35069250-9	2021	Finally, inhibition of the PGE2 receptor, EP1, in CA-SPAK mice partially restored potassium homeostasis as it partially rescued ROMK protein abundance, but not ENaC.	Potassium	82-91	prostaglandin E receptor 1 (subtype EP1)	Mus musculus	42-45
35212957-1	2022	Potassium ion (K+) efflux is often considered as an upstream signaling event of NLRP3 activation.	Potassium	0-9	NLR family pyrin domain containing 3	Homo sapiens	80-85
35069250-9	2021	Finally, inhibition of the PGE2 receptor, EP1, in CA-SPAK mice partially restored potassium homeostasis as it partially rescued ROMK protein abundance, but not ENaC.	Potassium	82-91	serine/threonine kinase 39	Mus musculus	53-57
35070968-1	2021	Background: This meta-analysis was designed to explore the relationship between the level of serum potassium and the treatment effect of epidermal growth factor receptor (EGFR) antagonist in advanced non-small cell lung cancer (aNSCLC).	Potassium	99-108	epidermal growth factor receptor	Homo sapiens	137-169
35070968-1	2021	Background: This meta-analysis was designed to explore the relationship between the level of serum potassium and the treatment effect of epidermal growth factor receptor (EGFR) antagonist in advanced non-small cell lung cancer (aNSCLC).	Potassium	99-108	epidermal growth factor receptor	Homo sapiens	171-175
35087712-6	2022	The pro-arrhythmic action results from drug-induced inhibition of Kv11.1 (hERG) channels interfering with the repolarizing potassium IKr currents, leading to long QT and increased risk of triggered arrhythmias.	Potassium	123-132	potassium voltage-gated channel subfamily H member 2	Homo sapiens	66-72
35087712-6	2022	The pro-arrhythmic action results from drug-induced inhibition of Kv11.1 (hERG) channels interfering with the repolarizing potassium IKr currents, leading to long QT and increased risk of triggered arrhythmias.	Potassium	123-132	ETS transcription factor ERG	Homo sapiens	74-78
35087712-9	2022	Inflammatory cytokines IL-6 and TNF-alpha inhibit IKr and Ito repolarizing potassium currents.	Potassium	75-84	interleukin 6	Homo sapiens	23-27
35087712-9	2022	Inflammatory cytokines IL-6 and TNF-alpha inhibit IKr and Ito repolarizing potassium currents.	Potassium	75-84	tumor necrosis factor	Homo sapiens	32-41
35086445-5	2022	It was shown that the assembly of GroEL occurs without the addition of magnesium and potassium ions, as is commonly believed.	Potassium	85-94	heat shock protein family D (Hsp60) member 1	Homo sapiens	34-39
35559886-5	2022	It was found that aggregated size and PAHs could activate the NLRP3 inflammasome through lysosome rupture and potassium efflux, respectively.	Potassium	110-119	NLR family pyrin domain containing 3	Homo sapiens	62-67
35040153-8	2022	The traits associated with this Meta-QTL were root and shoot sodium and potassium concentration and leaf chlorophyll content.	Potassium	72-81	homoserine O-succinyltransferase	Glycine max	32-36
2604739-6	1989	In contrast, 7-ethoxyresorufin O-deethylase activity (mediated by P-450c) in beta-naphthoflavone-induced rat hepatic microsomes was inhibited to a lesser extent (Ki = 2.4 microM) in relation to the Ks value (0.5 microM).	Potassium	198-200	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	66-72
35022288-12	2022	Patients with dRTA typically presented with nephrocalcinosis (80%), as well as poor weight gain and failure to thrive (86%), and medical treatment included sodium bicarbonate and potassium replacement.	Potassium	179-188	rta	Drosophila melanogaster	14-18
35465284-3	2022	The sodium-potassium-chloride co-transporter isoform 1 (NKCC1), localized at the basolateral surface of the lung epithelium, drives water transport via back transport of Na+ and Cl- to the alveolar air space.	Potassium	11-20	solute carrier family 12 member 2	Homo sapiens	56-61
2574573-5	1989	Furthermore, GPE had a potent stimulatory effect on the potassium induced release of acetylcholine from rat cortical slices.	Potassium	56-65	glycophorin E (MNS blood group)	Homo sapiens	13-16
8048549-0	1994	Hydrogen and potassium regulation of (pro)renin processing and secretion.	Potassium	13-22	renin	Homo sapiens	42-47
2573603-4	1989	In cells treated with the potassium ionophore, nonactin, both hsp 58 and grp 75 were observed to accumulate in precursor form.	Potassium	26-35	heat shock protein 90 beta family member 2, pseudogene	Homo sapiens	62-65
2573603-4	1989	In cells treated with the potassium ionophore, nonactin, both hsp 58 and grp 75 were observed to accumulate in precursor form.	Potassium	26-35	heat shock protein family A (Hsp70) member 9	Homo sapiens	73-79
2607517-8	1989	The relationships of DBP with body mass index and with the urinary sodium: potassium ratio were also 0.2 mmHg/kg/m2 and 0.8 mmHg/unit steeper (P less than 0.05) in post- than in pre-menopausal subjects.	Potassium	75-84	D-box binding PAR bZIP transcription factor	Homo sapiens	21-24
2557729-0	1989	Perchlorate stimulates potassium-induced growth hormone release in cultured rat somatotrophs.	Potassium	23-32	gonadotropin releasing hormone receptor	Rattus norvegicus	41-55
2576204-4	1989	It is concluded, that the plasma potassium level is reduced mainly by beta 2-adrenoceptor stimulation.	Potassium	33-42	beta-2 adrenergic receptor	Canis lupus familiaris	70-89
2532482-0	1989	Aldosterone and renin inhibition by atrial natriuretic factor in potassium-loaded rats.	Potassium	65-74	renin	Rattus norvegicus	16-21
2532482-0	1989	Aldosterone and renin inhibition by atrial natriuretic factor in potassium-loaded rats.	Potassium	65-74	natriuretic peptide A	Rattus norvegicus	36-61
2532482-4	1989	Infusion of ANF at 45 ng.kg-1.min-1 in potassium-loaded rats lowered aldosterone secretion to 1.32 +/- 0.21 ng/min (P less than 0.05) but did not significantly reduce PRA (11 +/- 2 ng ANG I.ml-1.h-1 (P greater than 0.05).	Potassium	39-48	natriuretic peptide A	Rattus norvegicus	12-15
2532482-8	1989	These results indicate that ANF can inhibit chronic potassium-stimulated aldosterone secretion in the rat independently of its inhibitory actions on renin release.	Potassium	52-61	natriuretic peptide A	Rattus norvegicus	28-31
2557769-2	1989	Recordings of the outward current(s), which is responsible for the resting potential and early repolarization of the action potential in human right atrium, consistently showed that this tissue has 1) a relatively small inwardly rectifying background potassium current (IK1) which generates the resting potential in mammalian ventricular tissue and Purkinje fibers, and 2) a large time- and voltage-dependent, but Ca2(+)-independent, transient outward current.	Potassium	251-260	hyaluronan synthase 1	Homo sapiens	194-199
2557769-2	1989	Recordings of the outward current(s), which is responsible for the resting potential and early repolarization of the action potential in human right atrium, consistently showed that this tissue has 1) a relatively small inwardly rectifying background potassium current (IK1) which generates the resting potential in mammalian ventricular tissue and Purkinje fibers, and 2) a large time- and voltage-dependent, but Ca2(+)-independent, transient outward current.	Potassium	251-260	IKAROS family zinc finger 1	Homo sapiens	270-273
2819470-6	1989	GLP-1-(7-36)NH2 was released from hypothalamic tissue slices in a calcium-dependent fashion by potassium-induced depolarization.	Potassium	95-104	glucagon	Rattus norvegicus	0-5
2553694-1	1989	In view of the striking homology among various ion-translocating ATPases including Na,K-ATPase, Ca-ATPase, and H,K-ATPase, and the recent evidence that protons can replace cytoplasmic sodium as well as potassium in the reaction mechanism of the Na,K-ATPase (Polvani, C., and Blostein, R. (1988) J. Biol.	Potassium	202-211	dynein axonemal heavy chain 8	Homo sapiens	96-121
2531741-1	1989	Sodium-translocating ATPase in the fermentative bacterium Streptococcus faecalis exchanges sodium for potassium ions.	Potassium	102-111	ATPase	Enterococcus faecalis	21-27
2479142-1	1989	Calcium (Ca2+)-dependent channels may be classified in three broad categories, which are, respectively, selective for potassium ions, for chloride ions, and for monovalent cations.	Potassium	118-127	carbonic anhydrase 2	Homo sapiens	9-12
2612564-8	1989	Inhibition of calmodulin-dependent enzymes by W7 (greater than 10 microM) reduced the maximum tension evoked by potassium and NA to a similar extent.	Potassium	112-121	calmodulin-3	Cavia porcellus	14-24
2804664-4	1989	However, locally applied CCK-8S potentiated the potassium-evoked overflow of dopamine (DA) into the extracellular space in both the caudate and nucleus accumbens.	Potassium	48-57	cholecystokinin	Rattus norvegicus	25-28
2804664-6	1989	These data support a facilitatory effect of CCK-8S on potassium-evoked overflow from DA-containing nerve terminals in the urethane anesthetized rat that is likely mediated through a peripheral type CCK receptor.	Potassium	54-63	cholecystokinin	Rattus norvegicus	44-47
2804664-6	1989	These data support a facilitatory effect of CCK-8S on potassium-evoked overflow from DA-containing nerve terminals in the urethane anesthetized rat that is likely mediated through a peripheral type CCK receptor.	Potassium	54-63	cholecystokinin	Rattus norvegicus	198-201
2515752-6	1989	The timing of the effects of GRF on potassium outflow is consistent with the hypothesis that reduced potassium outflow is involved in somatotroph depolarization leading to increased exocytosis, followed by a later increase in potassium outflow leading to repolarization.	Potassium	36-45	growth hormone releasing hormone	Rattus norvegicus	29-32
2532996-0	1989	Renal effects of atrial natriuretic factor (99-126) in potassium loaded sheep.	Potassium	55-64	natriuretic peptides A	Ovis aries	17-42
2515752-6	1989	The timing of the effects of GRF on potassium outflow is consistent with the hypothesis that reduced potassium outflow is involved in somatotroph depolarization leading to increased exocytosis, followed by a later increase in potassium outflow leading to repolarization.	Potassium	101-110	growth hormone releasing hormone	Rattus norvegicus	29-32
2515752-6	1989	The timing of the effects of GRF on potassium outflow is consistent with the hypothesis that reduced potassium outflow is involved in somatotroph depolarization leading to increased exocytosis, followed by a later increase in potassium outflow leading to repolarization.	Potassium	101-110	growth hormone releasing hormone	Rattus norvegicus	29-32
2790482-6	1989	In slices of hippocampus, which contain both IL-2-like immunoreactive material and specific IL-2 sites, exogenous IL-2 significantly decreased the potassium (25 mM)-evoked, but not the basal, release of acetylcholine.	Potassium	147-156	interleukin 2	Rattus norvegicus	45-49
2790482-6	1989	In slices of hippocampus, which contain both IL-2-like immunoreactive material and specific IL-2 sites, exogenous IL-2 significantly decreased the potassium (25 mM)-evoked, but not the basal, release of acetylcholine.	Potassium	147-156	interleukin 2	Rattus norvegicus	92-96
2790482-6	1989	In slices of hippocampus, which contain both IL-2-like immunoreactive material and specific IL-2 sites, exogenous IL-2 significantly decreased the potassium (25 mM)-evoked, but not the basal, release of acetylcholine.	Potassium	147-156	interleukin 2	Rattus norvegicus	92-96
2517056-3	1989	The results show that (1) intra-RBC potassium level in the HBP was lower than that in NBP.	Potassium	36-45	heme binding protein 1	Homo sapiens	59-62
2517056-7	1989	No difference was found between the FH+ and FH- in the plasma sodium concentrations; (3) Mean 8-hour night urinary potassium excretion expressed as mmol/g creatinine, was lower in HBP than in NBP; (4) After the saline load test the 4-hour urinary sodium excretion was significantly higher in HBP.	Potassium	115-124	heme binding protein 1	Homo sapiens	180-183
2507286-5	1989	To determine the influence of membrane depolarization on VIP release, the potassium concentration in the medium was increased to 30 and 56 mM, inducing a marked increase in medium VIP concentrations.	Potassium	74-83	vasoactive intestinal peptide	Rattus norvegicus	180-183
2514396-0	1989	Lidocaine inhibits dispersed anterior pituitary cell thyrotropin and prolactin secretion induced by thyrotropin-releasing hormone or high medium potassium.	Potassium	145-154	prolactin	Rattus norvegicus	69-78
2677612-3	1989	Compared with bed-rested controls, the septic patients showed an insulin-induced plasma clearance of potassium, which was 183% higher (P less than .001), and a concomitant glucose clearance, which was 52% lower (P less than .001).	Potassium	101-110	insulin	Homo sapiens	65-72
2677612-8	1989	It is concluded that septic and postburn insulin resistance differ in that peripheral glucose uptake in sepsis, but not nonseptic burn injury, is refractory to pharmacologic insulin stimulation, whereas in both states insulin effectively stimulates potassium uptake.	Potassium	249-258	insulin	Homo sapiens	41-48
2575716-5	1989	CPHNA at a concentration of 10(-4) M increased both the basal and potassium stimulated recovery of TRH released from hypothalamic slices by approximately two-fold.	Potassium	66-75	thyrotropin releasing hormone	Rattus norvegicus	99-102
2556456-0	1989	Potassium homeostasis during angiotensin-converting enzyme inhibition with enalapril.	Potassium	0-9	angiotensin I converting enzyme	Homo sapiens	29-58
2608159-0	1989	Sodium and potassium uptake in primary cultures of rat astroglial cells induced by long-term exposure to the basic astroglial growth factor (AGF2).	Potassium	11-20	myotrophin	Rattus norvegicus	126-139
2586636-0	1989	Effects of cromakalim (BRL 34915) on potassium conductances in CA3 neurons of the guinea-pig hippocampus in vitro.	Potassium	37-46	carbonic anhydrase 3	Cavia porcellus	63-66
2603269-4	1989	Methohexitone, suxamethonium and ECT in combination cause a rise in serum potassium which is not clinically important unless pre-induction level is abnormally high, and prolonged convulsion does not exaggerate this rise.	Potassium	74-83	ECT	Homo sapiens	33-36
2559967-13	1989	We conclude that this adenosine inhibition is mediated by an increase in a voltage- and calcium-insensitive potassium conductance in CA1 neurones.	Potassium	108-117	carbonic anhydrase 1	Rattus norvegicus	133-136
2573406-4	1989	The hyperpolarizing response to SS-14 occurred in virtually all neurons tested and appeared to result from a direct action on DLSN neurons mediated by an increased permeability to potassium ions.	Potassium	180-189	somatostatin	Rattus norvegicus	32-37
2504539-4	1989	Coronary potassium clearance was inversely related to the myocardial [H+], PCO2, and lactate production.	Potassium	9-18	PCO2	Sus scrofa	75-79
2570066-6	1989	Although palytoxin depolarizes the membrane, the observation that potassium-induced depolarization of the membrane does not cause a decrease in EGF binding, in conjunction with the fact that monensin hyperpolarizes the membrane, indicates that depolarization of the membrane is not responsible for palytoxin-induced changes in the EGF receptor.	Potassium	66-75	epidermal growth factor receptor	Mus musculus	331-343
2573312-1	1989	Administration of the beta 2 adrenergic agonists fenoterol, salbutamol and terbutaline to volunteers significantly reduced plasma potassium concentration in a double-blind crossover study.	Potassium	130-139	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	22-28
2752057-8	1989	Permeation analysis showed that gel porosity (measured as Ks) decreased in gels formed at higher fibrin and thrombin concentrations in agreement with the porosity observed by microscopy.	Potassium	58-60	coagulation factor II, thrombin	Homo sapiens	108-116
2606893-4	1989	A protein factor, which could restore the activity of immunoaffinity-purified DNA polymerase alpha-primase complex in the potassium-free reaction mixture, was separated from biochemically purified DNA polymerase alpha.	Potassium	122-131	DNA polymerase alpha 1, catalytic subunit	Homo sapiens	78-98
2476911-3	1989	CGRP application to potassium-pre-contracted human epicardial coronary arteries (0.4-0.6 mm in inner diameter) induced a concentration-dependent, long-lasting relaxation.	Potassium	20-29	calcitonin related polypeptide alpha	Homo sapiens	0-4
2676789-1	1989	This is an historical review of the articles published in English on the use of vitreous potassium to determine the PMI.	Potassium	89-98	transmembrane protein 11	Homo sapiens	116-119
2765877-1	1989	The effects of angiotensin I and II on basal potassium-induced release of [3H]acetylcholine were investigated in slices of rat entorhinal cortex.	Potassium	45-54	angiotensinogen	Rattus norvegicus	15-35
2765877-3	1989	Angiotensin II (10(-9)-10(-5) M) (but not angiotensin I) reduced the potassium-induced release of [3H]acetylcholine in a concentration-related manner to 60% of control levels, but did not effect basal tritium release.	Potassium	69-78	angiotensinogen	Rattus norvegicus	0-14
2477512-1	1989	Both 5-HT and the 9 amino acid neuropeptide SCPb modulate 3 ionic currents in B15, enhancing a voltage-dependent inward sodium current, decreasing an outward potassium current and increasing an inward rectifying potassium current.	Potassium	212-221	NADH:ubiquinone oxidoreductase subunit B4	Homo sapiens	78-81
2697984-5	1989	In adrenal capsular explant cultures, a converting enzyme inhibitor can lower angiotensin II production and reduce the stimulation of aldosterone by potassium, suggesting that this system is involved in the aldosterone response to potassium.	Potassium	231-240	angiotensinogen	Homo sapiens	78-92
2554957-0	1989	Acid dissociation constant and apparent nucleophilicity of lysine-501 of the alpha-polypeptide of sodium and potassium ion activated adenosinetriphosphatase.	Potassium	109-118	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	133-156
2546373-3	1989	CT also caused a significant increase of the potassium concentration in submandibular saliva.	Potassium	45-54	calcitonin-related polypeptide alpha	Rattus norvegicus	0-2
2668254-6	1989	Insulin action on glucose uptake and tyrosine release of the thighs at mean plasma insulin concentrations of 67 (clamp step I) and 447 microU/ml (clamp step II) was decreased by immobilization, whereas immobilization did not affect insulin action on thigh exchange of free fatty acids, glycerol, O2, or potassium.	Potassium	303-312	insulin	Homo sapiens	0-7
2674445-9	1989	Finally, in CHF a variety of proarrhythmic factors, such as left ventricular dysfunction, raised catecholamine levels and, in particular, decreased potassium concentrations, are influenced beneficially by ACE inhibitors.	Potassium	148-157	angiotensin-converting enzyme	Sus scrofa	205-208
2549328-2	1989	The stimulatory effect of potassium (50 mM) on alpha-MSH release was completely blocked by cadmium (1 mM) a calcium competitor which indifferently blocks T-, L-and N-type VOC channels.	Potassium	26-35	proopiomelanocortin	Rattus norvegicus	47-56
2666870-11	1989	A third study was conducted to assess the effects of anisomycin on basal and potassium (K+)-stimulated LHRH release from superfused ME explants.	Potassium	77-86	gonadotropin releasing hormone 1	Rattus norvegicus	103-107
2602234-0	1989	Cardiac arrhythmias during acute exacerbations of chronic airflow limitation: effect of fall in plasma potassium concentration induced by nebulised beta 2-agonist therapy.	Potassium	103-112	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	148-154
2602234-1	1989	The effect on cardiac rhythm of the fall in plasma potassium concentration induced by nebulised beta2-agonist therapy was studied in 20 patients admitted to hospital with an acute exacerbation of their reversible chronic airflow limitation.	Potassium	51-60	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	96-101
2505939-1	1989	The sciatic motor nerve conduction velocity of mutant diabetic C57BL/Ks mice was significantly improved from 30.0 +/- 1.4 to 38.0 +/- 4.6 m/s by treatment with the aldose reductase inhibitor 1-[(beta-naphthyl)sulfonyl]hydantoin (30 mg/kg/d) for 2 weeks.	Potassium	69-71	aldo-keto reductase family 1, member B3 (aldose reductase)	Mus musculus	164-180
2545834-10	1989	The Ca conductance induced by high potassium was reduced in a dose-dependent manner by nifedipine (ED50 = 5 X 10(-7) M), indicating that a high-threshold voltage-dependent calcium channel was present.	Potassium	35-44	calcium voltage-gated channel subunit alpha1 I	Rattus norvegicus	154-187
2545444-4	1989	The hypokalemia is the result of passive and VIP-induced active secretion of potassium by colonic epithelial cells.	Potassium	77-86	vasoactive intestinal peptide	Homo sapiens	45-48
2773656-0	1989	Does clonidine- or neuropeptide Y-mediated inhibition of ATP secretion from sympathetic nerves operate primarily by increasing a potassium conductance?	Potassium	129-138	neuropeptide Y	Homo sapiens	19-33
2542723-5	1989	These changes can be ascribed to the effects of the rapid insulin-induced plasma potassium decrease on plasma renin activity and aldosterone secretion because they did not occur in a control clamp study with a potassium infusion.	Potassium	81-90	renin	Homo sapiens	110-115
2541447-0	1989	Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells.	Potassium	100-109	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-14
2723735-2	1989	Focal electrographic seizures arose in the CA1 region of rat hippocampal slices bathed in elevated (8.5 mM) external potassium [( K+]o).	Potassium	117-126	carbonic anhydrase 1	Rattus norvegicus	43-46
2541447-2	1989	Here we report the presence of voltage-activated inward and outward rectifying potassium currents and the inhibition of the anomalous inward rectifying potassium current by angiotensin II (ANG-II).	Potassium	152-161	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	173-187
2541447-2	1989	Here we report the presence of voltage-activated inward and outward rectifying potassium currents and the inhibition of the anomalous inward rectifying potassium current by angiotensin II (ANG-II).	Potassium	152-161	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	189-195
2547922-1	1989	1) The primary receptor mechanism of catecholamine-induced myocardial potassium uptake is beta 1-adrenoceptor stimulation.	Potassium	70-79	adrenoceptor beta 1	Homo sapiens	90-109
2476868-4	1989	ANP also decreased the rise in [Ca2+]i induced by high potassium (K+) depolarization.	Potassium	55-64	natriuretic peptide A	Homo sapiens	0-3
2540883-7	1989	In the hippocampus, which is highly enriched with specific [125I]IGF-1 binding sites in both neonatal and adult rat brain, IGF-1 significantly altered the potassium-evoked (25 mM) release of acetylcholine (ACh) from slices of adult, but not immature (6- and 18-day-old), rat brain.	Potassium	155-164	insulin-like growth factor 1	Rattus norvegicus	65-70
2540883-7	1989	In the hippocampus, which is highly enriched with specific [125I]IGF-1 binding sites in both neonatal and adult rat brain, IGF-1 significantly altered the potassium-evoked (25 mM) release of acetylcholine (ACh) from slices of adult, but not immature (6- and 18-day-old), rat brain.	Potassium	155-164	insulin-like growth factor 1	Rattus norvegicus	123-128
2747008-1	1989	Plasma potassium lowering effect of a selective beta-2 adrenergic stimulant, terbutaline sulfate (TRB) was investigated in fourteen patients with chronic renal failure (CRF) receiving maintenance hemodialysis.	Potassium	7-16	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	48-54
2534969-8	1989	Nasal insufflation of 1-desamino-8-D-arginine-vasopressin induced both an increase in potassium excretion and a decrease in calcium and magnesium excretion.	Potassium	86-95	arginine vasopressin	Homo sapiens	46-57
2747008-6	1989	Thus, a beta-2 selective adrenergic stimulant, terbutaline sulfate may be useful for acute treatment of hyperkalemia in CRF patients by way of the stimulation of potassium uptake in the cells.	Potassium	162-171	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	8-14
2784056-5	1989	Also acute renal hCGRP induced effects were observed, as a significant increase in urinary volume and in the urinary calcium, sodium, potassium, and chloride excretion.	Potassium	134-143	calcitonin related polypeptide alpha	Homo sapiens	17-22
2713547-1	1989	The analysis of cardiac glycosides by the desorption/ionization (D/I) mass spectrometric technique potassium ion ionization of desorbed species (K+IDS) is presented.	Potassium	99-108	iduronate 2-sulfatase	Homo sapiens	147-150
2565211-4	1989	This cytochrome, designated P-450(CsA), exhibited a type I binding spectrum in the presence of CsA with a Ks(app) of 25 microM, a molecular weight of 52 kDa on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and a maximal absorbance at 449 nm when reduced in the presence of carbon monoxide.	Potassium	106-108	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	28-38
2521924-6	1989	The results show that development of V beta 17+ CD4-CD8+ T cells in the SJL H-2s mouse strain is selectively abrogated by blocking class I-Ks molecules but is unaffected by blocking class I-Ds molecules.	Potassium	139-141	CD4 antigen	Mus musculus	48-51
2665998-10	1989	The serum immunoreactive insulin (IRI) was elevated from the basal level to 289 microU/l, showing the prominent peak response at 30 min after the load, and both the serum potassium and the grasping power decreased significantly, although the blood glucose fluctuated within the normal level.	Potassium	171-180	insulin	Homo sapiens	25-32
2708783-5	1989	At sea, the potassium concentration of both unstimulated and stimulated saliva was significantly reduced, while sodium concentration was consistently elevated.	Potassium	12-21	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	3-6
2545282-0	1989	[Role of cAMP in the regulation of adrenal mineralocorticoid function by potassium ions].	Potassium	73-82	cathelicidin antimicrobial peptide	Cavia porcellus	9-13
2496078-4	1989	Furthermore, prior contractions directed glucose uptake toward glycogen synthesis and increased insulin effects on thigh O2 consumption and at some insulin concentrations on potassium exchange.	Potassium	174-183	insulin	Homo sapiens	148-155
2527408-8	1989	In vivo study showed that ANP was released from the rat spinal cord by depolarizing concentration of potassium.	Potassium	101-110	natriuretic peptide A	Rattus norvegicus	26-29
2543183-8	1989	Potassium ion permeabilities calculated from the electrical conductances average 8.5 x 10(-7), 3.4 x 10(-5), 5.7 x 10(-5), and 80 x 10(-5) cm sec-1 for brain, skin, muscle and mesenteric microvessels, respectively.	Potassium	0-9	secretory blood group 1, pseudogene	Homo sapiens	142-147
2694763-5	1989	The most important hormones involved in the regulation of internal potassium balance are the catecholamines, insulin and aldosterone.	Potassium	67-76	insulin	Homo sapiens	109-116
2803280-2	1989	4-beta-phorbol-12,13-dibutyrate (PDB), an activator of protein kinase C (PKC), enhanced the potassium-evoked overflow of 14C.	Potassium	92-101	protein kinase C, gamma	Rattus norvegicus	55-71
2803280-2	1989	4-beta-phorbol-12,13-dibutyrate (PDB), an activator of protein kinase C (PKC), enhanced the potassium-evoked overflow of 14C.	Potassium	92-101	protein kinase C, gamma	Rattus norvegicus	73-76
2695195-0	1989	Peripheral muscle glucose and potassium transport in a family with acanthosis nigricans and insulin resistance.	Potassium	30-39	insulin	Homo sapiens	92-99
2695195-1	1989	This study was designed to determine the forearm exchange of glucose and potassium in four members of a family exhibiting acanthosis nigricans and insulin resistance.	Potassium	73-82	insulin	Homo sapiens	147-154
2695195-4	1989	In the latter patient, the dissociation observed between glucose and potassium transport suggests several manners of differential impairment of insulin action and/or steps distal to the insulin receptor as being responsible for insulin resistance.	Potassium	69-78	insulin receptor	Homo sapiens	186-202
2563217-2	1989	We considered that terbutaline-induced hypokalemia may be due to the insulin-induced shift of potassium (K+) from the extracellular to the intracellular space.	Potassium	94-103	insulin	Homo sapiens	69-76
2483949-11	1989	In contrast, 10(-7) M NPY contracted femoral veins by up to 68% relative to 60 mM potassium induced contraction, and there was no potentiation of alpha-adrenoceptor mediated contractions.	Potassium	82-91	neuropeptide Y	Rattus norvegicus	22-25
2695195-4	1989	In the latter patient, the dissociation observed between glucose and potassium transport suggests several manners of differential impairment of insulin action and/or steps distal to the insulin receptor as being responsible for insulin resistance.	Potassium	69-78	insulin	Homo sapiens	144-151
2670218-3	1989	Angiotensin-converting enzyme (ACE) inhibitors are lipid neutral and associated with few metabolic side effects, and may be considered over agents that cause adverse effects on such parameters as serum cholesterol, glucose, potassium, and uric acid levels.	Potassium	224-233	angiotensin I converting enzyme	Homo sapiens	0-29
2670218-3	1989	Angiotensin-converting enzyme (ACE) inhibitors are lipid neutral and associated with few metabolic side effects, and may be considered over agents that cause adverse effects on such parameters as serum cholesterol, glucose, potassium, and uric acid levels.	Potassium	224-233	angiotensin I converting enzyme	Homo sapiens	31-34
2670220-2	1989	In patients with chronic heart failure, angiotensin-converting enzyme (ACE) inhibitors, such as captopril, enalapril, and quinapril, have been shown to improve hemodynamics, reduce symptoms of fatigue and dyspnea, increase exercise capacity, correct hyponatremia, reduce diuretic requirements and ventricular arrhythmias, and conserve potassium and magnesium.	Potassium	335-344	angiotensin I converting enzyme	Homo sapiens	40-69
2670220-2	1989	In patients with chronic heart failure, angiotensin-converting enzyme (ACE) inhibitors, such as captopril, enalapril, and quinapril, have been shown to improve hemodynamics, reduce symptoms of fatigue and dyspnea, increase exercise capacity, correct hyponatremia, reduce diuretic requirements and ventricular arrhythmias, and conserve potassium and magnesium.	Potassium	335-344	angiotensin I converting enzyme	Homo sapiens	71-74
2533087-14	1989	In conclusion, it is suggested that activation of two different muscarinic receptors (neither of which is the M1 receptor) on mPRF neurons results in two different responses, a decrease in a voltage-insensitive potassium conductance and an increase in the anomalous rectifier.	Potassium	211-220	Spi-C transcription factor (Spi-1/PU.1 related)	Mus musculus	126-130
2564623-4	1989	Potassium- or veratridine-induced membrane depolarization of cultured neonatal sympathetic neurons decreased levels of SS mRNA but elevated levels of TH mRNA.	Potassium	0-9	tyrosine hydroxylase	Rattus norvegicus	150-152
2540019-2	1989	Addition of 10(-6) M quinpirole, a D2-dopamine receptor agonist, to the superfusion medium caused a significant (P less than 0.001) reduction in the amount of alpha-MSH released upon depolarisation with 50 mM potassium from 319 +/- 37% to 110 +/- 16% of basal release in normal ACSF (mean +/- S.E.M.).	Potassium	209-218	dopamine receptor D2	Rattus norvegicus	35-55
2540019-2	1989	Addition of 10(-6) M quinpirole, a D2-dopamine receptor agonist, to the superfusion medium caused a significant (P less than 0.001) reduction in the amount of alpha-MSH released upon depolarisation with 50 mM potassium from 319 +/- 37% to 110 +/- 16% of basal release in normal ACSF (mean +/- S.E.M.).	Potassium	209-218	proopiomelanocortin	Rattus norvegicus	159-168
2540019-4	1989	Sulpiride, a D2-dopamine receptor antagonist, at a concentration of 10(-6) M, induced a significant (P less than 0.05) increase of both basal and potassium-stimulated alpha-MSH release to 203 +/- 21% and 447 +/- 88% of basal release in normal ACSF respectively.	Potassium	146-155	proopiomelanocortin	Rattus norvegicus	167-176
2754431-0	1989	Neuropeptide Y increases the inhibitory effects of clonidine on potassium evoked 3H-noradrenaline but not 3H-5-hydroxytryptamine release from synaptosomes of the hypothalamus and the frontoparietal cortex of the male Sprague-Dawley rat.	Potassium	64-73	neuropeptide Y	Rattus norvegicus	0-14
2565849-10	1989	Thyrotropin-releasing hormone (TRH, 10(-4) M) caused a slight and statistically insignificant increase in potassium-evoked ACh release.	Potassium	106-115	thyrotropin releasing hormone	Rattus norvegicus	0-29
2565849-10	1989	Thyrotropin-releasing hormone (TRH, 10(-4) M) caused a slight and statistically insignificant increase in potassium-evoked ACh release.	Potassium	106-115	thyrotropin releasing hormone	Rattus norvegicus	31-34
2565849-11	1989	DN-1417, a TRH analogue, at a concentration of 10(-4) M significantly increased potassium-evoked ACh release.	Potassium	80-89	thyrotropin releasing hormone	Rattus norvegicus	11-14
2626031-1	1989	We studied the effect of dietary sodium restriction (3 weeks) and high potassium intake (7 days) on transcriptional regulation of cytochrome P-450 cholesterol side chain cleavage (P-450 scc) and adrenodoxin (Adx) in rat adrenal glands.	Potassium	71-80	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	180-189
2501589-2	1989	At 3 years and 8 months of age, a serum potassium level of 6.8 mmol L-1 was found when blood gas measurement was normal.	Potassium	40-49	immunoglobulin kappa variable 1-16	Homo sapiens	68-71
2918302-6	1989	The monovalent cations, potassium and sodium, activated NAT by a similar mechanism which differed from the caused by the divalent cations.	Potassium	24-33	N-acetyltransferase 1	Rattus norvegicus	56-59
2918302-8	1989	At high potassium or sodium concentration the affinity of acetyl coenzyme A for NAT begins to decrease suggesting that excess monovalent cations can be inhibitory and may represent an endogenous regulatory mechanism controlling in vivo NAT activity.	Potassium	8-17	N-acetyltransferase 1	Rattus norvegicus	80-83
2918302-8	1989	At high potassium or sodium concentration the affinity of acetyl coenzyme A for NAT begins to decrease suggesting that excess monovalent cations can be inhibitory and may represent an endogenous regulatory mechanism controlling in vivo NAT activity.	Potassium	8-17	N-acetyltransferase 1	Rattus norvegicus	236-239
2915347-8	1989	Previously observed changes in these Ang II binding parameters in potassium-depleted rats was probably a consequence of other factors which were simultaneously altered by potassium deficiency.	Potassium	66-75	angiotensinogen	Rattus norvegicus	37-43
2915347-8	1989	Previously observed changes in these Ang II binding parameters in potassium-depleted rats was probably a consequence of other factors which were simultaneously altered by potassium deficiency.	Potassium	171-180	angiotensinogen	Rattus norvegicus	37-43
2593764-4	1989	Intravenous and intraarterial infusion of neurotensin increased net sodium, potassium, and water secretion, due to increased secretory fluxes, and increased hematocrits.	Potassium	76-85	neurotensin	Canis lupus familiaris	42-53
2593764-5	1989	Intraarterial neurotensin was not more effective than intravenous neurotensin except for stimulating potassium secretion.	Potassium	101-110	neurotensin	Canis lupus familiaris	14-25
2593764-6	1989	Neurotensin increased potassium secretion at 0.075 micrograms/min IA, increased sodium and water secretion at 0.75 micrograms/min IA and IV, and increased hematocrit at 7.5 micrograms/min IA and and IV.	Potassium	22-31	neurotensin	Canis lupus familiaris	0-11
2593764-9	1989	Neurotensin can increase potassium secretion at physiologic levels by a local effect and can increase sodium and water secretion at high physiological-pathological levels through a hormonal mechanism.	Potassium	25-34	neurotensin	Canis lupus familiaris	0-11
2464732-4	1989	On the other hand, nifedipine completely antagonized the extracellular high potassium- or Bay K 8644-induced inhibition of renin release.	Potassium	76-85	renin	Rattus norvegicus	123-128
2626031-8	1989	These results thus indicate that both sodium depletion and high potassium intake in rats could act at the transcriptional level of P-450scc and Adx, two components of a rate-limiting step in steroidogenesis leading to aldosterone production.	Potassium	64-73	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	131-139
20504484-5	1989	In addition, potassium-evoked release of cholinesterase was seen to occur in a pulsatile fashion which would have been masked by the poor time resolution of any of the "off-line" methods.	Potassium	13-22	butyrylcholinesterase	Homo sapiens	41-55
2682302-6	1989	Basal insulin levels were higher in the CRF patients and increased with the oral potassium and carbohydrate load in both controls and patients.	Potassium	81-90	insulin	Homo sapiens	6-13
2533973-5	1989	In healthy volunteers, however, the same dose of ANF increased urinary excretion of sodium, potassium, calcium, chloride and phosphorus as well as water, and creatinine clearances, and decreased plasma aldosterone.	Potassium	92-101	natriuretic peptide A	Homo sapiens	49-52
2747913-11	1989	Chromogranin B 420-493-like immunoreactivity release was stimulated from rat pituitary cells by high potassium ion concentrations.	Potassium	101-110	chromogranin B	Rattus norvegicus	0-14
2710278-4	1989	The release of [14C]glycine from P1 and P2 synaptosomal fractions was markedly increased by raising potassium concentration in the medium, in a partially Ca2+-dependent manner.	Potassium	100-109	crystallin gamma F, pseudogene	Homo sapiens	33-42
2725785-0	1989	[Pharmacologic and metabolic dependence of the delayed inactivated potassium outward current in the somatic membrane of snail neurons].	Potassium	67-76	snail family transcriptional repressor 1	Homo sapiens	120-125
2739866-0	1989	Parathyroid hormone interferes with extrarenal disposition of potassium in chronic renal failure.	Potassium	62-71	parathyroid hormone	Rattus norvegicus	0-19
2739866-3	1989	Therefore, it is possible that clinical states with excess PTH may affect potassium homeostasis.	Potassium	74-83	parathyroid hormone	Rattus norvegicus	59-62
2602427-7	1989	Exogenous IGF-1, EGF, and IL-2 significantly reduced the potassium (25 mM)-evoked release of acetylcholine (ACh) from slices of rat hippocampus.	Potassium	57-66	insulin-like growth factor 1	Rattus norvegicus	10-15
2602427-7	1989	Exogenous IGF-1, EGF, and IL-2 significantly reduced the potassium (25 mM)-evoked release of acetylcholine (ACh) from slices of rat hippocampus.	Potassium	57-66	interleukin 2	Rattus norvegicus	26-30
3058511-5	1988	Omission of potassium from the oocyte culture medium greatly facilitated insulin-induced meiotic maturation.	Potassium	12-21	insulin S homeolog	Xenopus laevis	73-80
2711375-2	1989	In the high potassium medium, survival of the sympathetic ganglion neurons was improved and catecholamine fluorescence of the nerve fibers increased with several days in culture, while acetylcholinesterase activity was slightly positive.	Potassium	12-21	acetylcholinesterase (Cartwright blood group)	Gallus gallus	185-205
2974728-7	1988	Addition of calcium to the MgATP complex of the ATPase caused an increase in the FITC inactivation rate, implying that during turnover there is a larger fraction of unliganded enzyme present, i.e., substrate binding is weaker (Ks is larger).	Potassium	227-229	dynein axonemal heavy chain 8	Homo sapiens	48-54
3060124-13	1988	It is concluded that pHi can influence the secretory activity of pancreatic islets, possibly via effects on potassium permeability and sodium-calcium exchange across the plasma membrane, resulting in altered mobilisation of calcium in the islet cell.	Potassium	108-117	glucose-6-phosphate isomerase	Rattus norvegicus	21-24
3057941-0	1988	Hyperkalemic cardiac arrest after cardiac surgery following high-dose glucose-insulin-potassium infusion for inotropic support.	Potassium	86-95	insulin	Homo sapiens	78-85
2854018-7	1988	ANP produced large increases in urine volume, urinary sodium and chloride excretion, and further decreased plasma potassium concentration in the ACTH-treated sheep.	Potassium	114-123	natriuretic peptides A	Ovis aries	0-3
2849310-1	1988	Insulin promotes potassium uptake into skeletal muscle by stimulating the activity of the Na+-K+ pump.	Potassium	17-26	insulin	Homo sapiens	0-7
2849310-7	1988	Under these conditions of fixed flow (7.0 +/- 0.8 ml.min-1.100 ml-1), ouabain still abolished the stimulatory effect of insulin on potassium uptake but had only a small (and statistically insignificant) effect on forearm glucose extraction (from 20 +/- 2 to 16 +/- 2%, P = N&gt;).	Potassium	131-140	insulin	Homo sapiens	120-127
3241258-4	1988	The urinary sodium to potassium ratio was significantly and positively correlated with SBP and DBP in both males and females.	Potassium	22-31	selenium binding protein 1	Homo sapiens	87-90
3264544-7	1988	Potassium supplementation (8% NaCl/3.6% potassium citrate) significantly enhanced relaxations to acetylcholine in salt-sensitive rats, while those to adenosine 5"-diphosphate and thrombin were either minimally affected or unchanged.	Potassium	0-9	coagulation factor II	Rattus norvegicus	179-187
3073091-4	1988	These data suggest that potassium metabolism plays a critical role in the mechanisms of insulin sensitivity.	Potassium	24-33	insulin	Homo sapiens	88-95
3241258-4	1988	The urinary sodium to potassium ratio was significantly and positively correlated with SBP and DBP in both males and females.	Potassium	22-31	D-box binding PAR bZIP transcription factor	Homo sapiens	95-98
3241258-9	1988	Urinary potassium was negatively correlated with SBP and DBP only in the 20-29 year age group.	Potassium	8-17	selenium binding protein 1	Homo sapiens	49-52
3241258-9	1988	Urinary potassium was negatively correlated with SBP and DBP only in the 20-29 year age group.	Potassium	8-17	D-box binding PAR bZIP transcription factor	Homo sapiens	57-60
3241258-10	1988	Urinary potassium (creatinine) was negatively correlated with DBP only in the south.	Potassium	8-17	D-box binding PAR bZIP transcription factor	Homo sapiens	62-65
3056038-4	1988	Potassium depletion also depressed parathyroid hormone (PTH)-stimulated adenylate cyclase activity in proximal straight tubules (PST) dissected from untreated but not collagenase-treated kidneys.	Potassium	0-9	parathyroid hormone	Oryctolagus cuniculus	35-54
3182866-4	1988	In the presence of alpha-naphthoflavone or progesterone, the Ks decreases to 0.8 microM, indicating that these two compounds serve as positive effectors of the binding of 22-ABC to cytochrome P-450 3c.	Potassium	61-63	cytochrome P450 3A6	Oryctolagus cuniculus	181-200
2976327-8	1988	The administration of ANP (2 micrograms/kg bodyweight) to rabbits in water diuresis did not alter systemic blood pressure but induced a marked natriuresis and increases in urine flow and potassium excretion.	Potassium	187-196	natriuretic peptides A	Oryctolagus cuniculus	22-25
2470415-1	1988	Injection of cAMP induces in snail neurons generator potential, which is related to an increase of sodium and decrease of potassium permeability of the neuron outer membrane.	Potassium	122-131	cathelicidin antimicrobial peptide	Homo sapiens	13-17
2850064-12	1988	Muscarine has been shown previously to increase the potassium conductance by an action at M2-receptors: the potassium currents induced by maximal concentrations of muscarine, baclofen and [Met5]enkephalin were non-additive, indicating that these agonists opened the same population of potassium channels.	Potassium	52-61	proenkephalin	Rattus norvegicus	194-204
2850064-12	1988	Muscarine has been shown previously to increase the potassium conductance by an action at M2-receptors: the potassium currents induced by maximal concentrations of muscarine, baclofen and [Met5]enkephalin were non-additive, indicating that these agonists opened the same population of potassium channels.	Potassium	108-117	proenkephalin	Rattus norvegicus	194-204
3154627-4	1988	A low-sodium diet or a high-potassium diet, or nephrectomy markedly increases the adrenal renin concentration in the zona glomerulosa cells without any effect on the fasciculata-medullary cells.	Potassium	28-37	renin	Homo sapiens	90-95
2853087-8	1988	The increase of plasma renin activity, in turn, is attributable both to the increased catecholamine concentrations and to the decreased potassium levels.	Potassium	136-145	renin	Homo sapiens	23-28
3052050-8	1988	On the other hand, insulin in glucose, 5 mU/kg/minute intravenously, effectively lowered plasma potassium levels from 5.62 to 4.70 mmol/liter, and hemodialysis induced the most rapid decline from 5.63 to 4.29 mmol/liter.	Potassium	96-105	insulin	Homo sapiens	19-26
3254766-8	1988	Plasma renin activity was significantly reduced in those animals receiving potassium after 5 weeks.	Potassium	75-84	renin	Rattus norvegicus	7-12
3254766-10	1988	It is proposed that a combination of increased systemic and/or renal prostacyclin and kallikrein synthesis may, in combination with reduced renin activity, contribute to the attenuation of blood pressure in potassium-supplemented spontaneously hypertensive rats.	Potassium	207-216	renin	Rattus norvegicus	140-145
2846057-9	1988	Benzamil, 1 mM, had no effect on passive calcium efflux and neither did the substitution of sucrose for potassium, which has been shown to affect Ca2+-Ca2+ exchange by the Na+-Ca2+ exchanger.	Potassium	104-113	solute carrier family 8 member A1	Canis lupus familiaris	172-190
3054273-6	1988	On the other hand renal kallikrein activity and connecting tubule cell morphology change in parallel with dietary potassium load indicating a coupling to potassium secretion.	Potassium	154-163	kallikrein related peptidase 4	Homo sapiens	24-34
3052110-1	1988	Extracellular high potassium inhibits renin release in vitro by increasing calcium concentrations in the juxtaglomerular cells.	Potassium	19-28	renin	Rattus norvegicus	38-43
3052110-2	1988	We found that the decreased response of renin release from rat kidney cortical slices in high potassium solution (20-80 mM) changed to a strikingly increased one in the presence of nifedipine at doses over 10(-6) M. We then examined the stimulatory effect of extracellular high potassium in the presence of nifedipine on renin release.	Potassium	94-103	renin	Rattus norvegicus	40-45
3052110-4	1988	High potassium plus nifedipine-induced increase in renin release was markedly attenuated by renal denervation.	Potassium	5-14	renin	Rattus norvegicus	51-56
3052110-9	1988	These observations suggest to us that the high potassium plus nifedipine-induced increase in renin release from the slices is mediated by norepinephrine derived from renal sympathetic nerves and that this neuronally released norepinephrine stimulates renin release via activation of beta-adrenoceptors.	Potassium	47-56	renin	Rattus norvegicus	93-98
3052110-9	1988	These observations suggest to us that the high potassium plus nifedipine-induced increase in renin release from the slices is mediated by norepinephrine derived from renal sympathetic nerves and that this neuronally released norepinephrine stimulates renin release via activation of beta-adrenoceptors.	Potassium	47-56	renin	Rattus norvegicus	251-256
2844436-7	1988	In the preparations, which were partially depolarized with an increase in extracellular potassium, CGRP induced slow response action potentials.	Potassium	88-97	calcitonin-related polypeptide alpha	Rattus norvegicus	99-103
3181619-1	1988	We have investigated the acute effects of elevated plasma potassium concentrations on the calcitonin (CT) mRNA level measured by dot-blot hybridization.	Potassium	58-67	calcitonin-related polypeptide alpha	Rattus norvegicus	90-100
3181619-1	1988	We have investigated the acute effects of elevated plasma potassium concentrations on the calcitonin (CT) mRNA level measured by dot-blot hybridization.	Potassium	58-67	calcitonin-related polypeptide alpha	Rattus norvegicus	102-104
3181619-2	1988	Plasma CT levels were significantly increased (X2) 30 min after potassium administration (1.2 mmol, KCl/100 g body weight) in adult female rats; a trend towards increased values was observed 10 min after treatment.	Potassium	64-73	calcitonin-related polypeptide alpha	Rattus norvegicus	7-9
3181619-4	1988	The amount of CT mRNA measured by dot-blot hybridization was statistically significantly increased 10 min and 30 min (around 47-55%) after potassium treatment.	Potassium	139-148	calcitonin-related polypeptide alpha	Rattus norvegicus	14-16
3181619-6	1988	It is suggested for the first time that the potassium-induced CT release is associated with a slight increase in CT mRNA level.	Potassium	44-53	calcitonin-related polypeptide alpha	Rattus norvegicus	62-64
3181619-6	1988	It is suggested for the first time that the potassium-induced CT release is associated with a slight increase in CT mRNA level.	Potassium	44-53	calcitonin-related polypeptide alpha	Rattus norvegicus	113-115
3272184-0	1988	Four cDNA clones from the Shaker locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes.	Potassium	88-97	Shaker	Drosophila melanogaster	26-32
3054273-6	1988	On the other hand renal kallikrein activity and connecting tubule cell morphology change in parallel with dietary potassium load indicating a coupling to potassium secretion.	Potassium	114-123	kallikrein related peptidase 4	Homo sapiens	24-34
3214676-0	1988	Potassium ion ionization of desorbed species (K+IDS): a rapid method for the screening of urine for organic acidemias.	Potassium	0-9	iduronate 2-sulfatase	Homo sapiens	48-51
3046266-3	1988	Because of changes in the renin-aldosterone system, the elderly may have problems maintaining sodium and potassium balance.	Potassium	105-114	renin	Homo sapiens	26-31
2853084-1	1988	Sodium and potassium ion-activated adenosinetriphosphatase (EC number 3.6.1.3) activity, measured as the uptake of 86 rubidium (an analogue of potassium) was determined on peripheral lymphocytes isolated from 20 normotensive obese subjects and 20 normal weight subjects.	Potassium	11-20	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	35-58
3206193-5	1988	When vasopressin was injected intravenously, plasma potassium concentration did not change significantly (-0.21 +/- 0.21 mmol/l) in LE rats, whilst it increased significantly (0.69 +/- 0.20 mmol/l, p less than 0.001; paired t-test) in the BDI rats.	Potassium	52-61	arginine vasopressin	Rattus norvegicus	5-16
3068066-3	1988	Incubation of neurointermediate lobes in Locke"s solution containing 3.3 mumol/l insulin resulted in an inhibition of oxytocin release under resting conditions as well as in a decrease of both vasopressin and oxytocin release during depolarization due to excess potassium.	Potassium	262-271	insulin	Homo sapiens	81-88
3139262-12	1988	In summary, these results provide evidence for the role of a G protein(s) in the mediation of the cAMP-independent increase in potassium conductance in 5-HT neurons of dorsal raphe nucleus induced by both 5-HT1A- and GABAB-receptors.	Potassium	127-136	5-hydroxytryptamine receptor 1A	Rattus norvegicus	205-211
3418519-0	1988	Norepinephrine and potassium induced calcium translocation in rat vas deferens.	Potassium	19-28	arginine vasopressin	Rattus norvegicus	66-69
3418519-4	1988	Stimulation of the vas deferens with 50 mM potassium caused a rapid influx of 45Ca (6-fold).	Potassium	43-52	arginine vasopressin	Rattus norvegicus	19-22
2903467-1	1988	In the in vitro hippocampal slice somatostatin has been shown to cause a direct hyperpolarization of CA 1 pyramidal neurons by increasing a potassium conductance which is resistant to blockade by tetraethylammonium 4-aminopyridine, or cesium ions.	Potassium	140-149	carbonic anhydrase 1	Homo sapiens	101-105
2856063-7	1988	High potassium depolarization significantly potentiated the decreased response of renin release, with no influence on the stimulation of the release by exposure to calcium.	Potassium	5-14	renin	Rattus norvegicus	82-87
2839527-4	1988	The results showed significant accumulation of calcium and loss of potassium after 3 and 4 days of recovery in the CA1 sector, which developed neuronal necrosis, but not in the CA3 sector, which showed only occasional damage.	Potassium	67-76	carbonic anhydrase 1	Rattus norvegicus	115-118
2970433-3	1988	In contrast, ANF-(99-122), 10 micrograms/kg, significantly increased renal blood flow (26 +/- 4.5%), reduced renal vascular resistance (24 +/- 2.9%) and arterial pressure (5.5 +/- 1.9%), and markedly increased urine flow rate (198 +/- 34%) and sodium (206 +/- 32%) and potassium (75 +/- 27%) excretion (p less than 0.05), being almost twice as effective in the first 10 minutes as was ANF-(99-119) infusion.	Potassium	269-278	natriuretic peptide A	Canis lupus familiaris	13-16
2970433-4	1988	During a brief infusion, ANF-(99-122) (10 micrograms/kg/min for 4 minutes) increased renal blood flow (24 +/- 2.7%), heart rate (18 +/- 5.7%), urine flow rate (199 +/- 25%), and sodium (290 +/- 81%) and potassium (104 +/- 17%) excretion.	Potassium	203-212	natriuretic peptide A	Canis lupus familiaris	25-28
2455669-2	1988	The BCECF fluorescence was calibrated in terms of pHi by using a nigericin-high potassium concentration method to equilibrate pHi and pHo.	Potassium	80-89	glucose-6-phosphate isomerase	Oryctolagus cuniculus	50-53
2901268-5	1988	In addition, alterations in potassium fluxes are particularly induced by nonselective beta-blockade and result in more pronounced decreases in the intracellular-extracellular potassium ratio during exercise than caused by placebo or beta 1-selective blockade.	Potassium	28-37	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	233-239
9959202-0	1988	Spin-parameter measurements in Lambda and KS production.	Potassium	42-44	spindlin 1	Homo sapiens	0-4
3291595-5	1988	In patients who have undergone treatment for congestive heart failure, serum and total body potassium are reduced, and this is closely and inversely related to the state of activation of the renin-angiotensin system.	Potassium	92-101	renin	Homo sapiens	191-196
2464206-8	1988	Treatment of the tissue with potassium permanganate causes protein AA and B2-microglobulin amyloid to lose their affinity to Congo red.	Potassium	29-38	major histocompatibility complex, class I, G	Homo sapiens	74-90
3046411-2	1988	In a prospective randomised study in 20 insulin-dependent diabetics who had minor surgery under general anaesthesia we compared the metabolic responses to intravenous glucose-insulin-potassium infusion with those who had conventional subcutaneous insulin administration.	Potassium	183-192	insulin	Homo sapiens	175-182
2968238-2	1988	In the present study, we observed rat alpha ANP to inhibit aldosterone secretion stimulated by 10 mM potassium with an IC50 of 0.15 +/- 0.02 nM (mean +/- SE) in dispersed rat adrenal glomerulosa cells.	Potassium	101-110	natriuretic peptide A	Rattus norvegicus	44-47
2968238-6	1988	When this same ANP-containing superfusate was incubated with dispersed adrenal glomerulosa cells, potassium-stimulated aldosterone secretion was inhibited by 90%, proving sustained biological potency of the superfused ANP.	Potassium	98-107	natriuretic peptide A	Rattus norvegicus	15-18
2968238-6	1988	When this same ANP-containing superfusate was incubated with dispersed adrenal glomerulosa cells, potassium-stimulated aldosterone secretion was inhibited by 90%, proving sustained biological potency of the superfused ANP.	Potassium	98-107	natriuretic peptide A	Rattus norvegicus	218-221
3043197-0	1988	TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cerevisiae.	Potassium	66-75	Trk1p	Saccharomyces cerevisiae S288C	0-4
3043197-2	1988	The gene that encodes this putative potassium transporter (TRK1) was cloned by its ability to relieve the potassium transport defect in trk1 cells.	Potassium	36-45	Trk1p	Saccharomyces cerevisiae S288C	59-63
3043197-2	1988	The gene that encodes this putative potassium transporter (TRK1) was cloned by its ability to relieve the potassium transport defect in trk1 cells.	Potassium	36-45	Trk1p	Saccharomyces cerevisiae S288C	136-140
3043197-6	1988	Haploid cells that contain a null allele of TRK1 (trk1 delta) rely on a low-affinity transporter for potassium uptake and, under certain conditions, exhibit energy-dependent loss of potassium, directly exposing the activity of a transporter responsible for the efflux of this ion.	Potassium	101-110	Trk1p	Saccharomyces cerevisiae S288C	44-48
3043197-6	1988	Haploid cells that contain a null allele of TRK1 (trk1 delta) rely on a low-affinity transporter for potassium uptake and, under certain conditions, exhibit energy-dependent loss of potassium, directly exposing the activity of a transporter responsible for the efflux of this ion.	Potassium	101-110	Trk1p	Saccharomyces cerevisiae S288C	50-54
3043197-6	1988	Haploid cells that contain a null allele of TRK1 (trk1 delta) rely on a low-affinity transporter for potassium uptake and, under certain conditions, exhibit energy-dependent loss of potassium, directly exposing the activity of a transporter responsible for the efflux of this ion.	Potassium	182-191	Trk1p	Saccharomyces cerevisiae S288C	44-48
3043197-6	1988	Haploid cells that contain a null allele of TRK1 (trk1 delta) rely on a low-affinity transporter for potassium uptake and, under certain conditions, exhibit energy-dependent loss of potassium, directly exposing the activity of a transporter responsible for the efflux of this ion.	Potassium	182-191	Trk1p	Saccharomyces cerevisiae S288C	50-54
3133995-6	1988	With GH, serum blood urea nitrogen (BUN) and potassium fell, whereas glucose and insulin tended to rise, and levels of insulin-like growth factor 1 increased three to fourfold.	Potassium	45-54	growth hormone 1	Homo sapiens	5-7
2837095-7	1988	These results show that oxytocin and cAMP stimulate a potassium conductance in the basolateral membrane and that the stimulation is not related to an increase in sodium entry through the apical membrane.	Potassium	54-63	oxytocin/neurophysin I prepropeptide	Homo sapiens	24-32
3401764-10	1988	We conclude that the predominant response of CA3 pyramidal cell dendrites to GABA application is a hyperpolarization mediated by GABAB receptors and probably carried by potassium ions.	Potassium	169-178	carbonic anhydrase 3	Oryctolagus cuniculus	45-48
3287913-1	1988	To elucidate a potential role for insulin-mediated extra-renal potassium disposal in the clinical syndrome of hypokalemic periodic paralysis, an obese affected man was studied using the euglycemic insulin clamp, which, in normal and obese subjects, produces predictable, insulin dose-dependent declines in plasma potassium levels.	Potassium	63-72	insulin	Homo sapiens	34-41
3287913-2	1988	During a 20 mU/m2/minute euglycemic clamp (insulin level, 88 microU/ml) procedure, while the patient with hypokalemic periodic paralysis demonstrated severe resistance to insulin-mediated glucose uptake (glucose uptake 50 percent of that of normal control subjects, n = 17), his plasma potassium declined to a degree similar to that seen in normal subjects.	Potassium	286-295	insulin	Homo sapiens	171-178
3287913-3	1988	During a subsequent higher dose, 200 mU/m2/minute insulin infusion (insulin level, 914 microU/ml), plasma potassium declined to 2.5 meq/liter, a value significantly below that seen in normal (n = 19) (3.3 +/- 0.1 meq/liter) and obese (n = 6) (3.2 +/- 0.1 meq/liter) subjects.	Potassium	106-115	insulin	Homo sapiens	68-75
3287913-8	1988	Enhanced sensitivity of potassium uptake systems to activation by insulin (and other factors) may be a central feature of this syndrome.	Potassium	24-33	insulin	Homo sapiens	66-73
2462373-4	1988	A significantly increased outflow of both SP-LI and NKA-LI was observed during perfusion of the lung with high potassium concentration (60 mM), the C-fiber activator capsaicin (1 microM), bradykinin (1 microM), histamine (100 microM), or the nicotinic agonist dimethylphenyl piperazinium (DMPP) (32 microM).	Potassium	111-120	tachykinin precursor 1	Homo sapiens	52-55
2973296-4	1988	Intravenous infusion of ANF for 2 h (1 microgram/mn) induced the expected increases in urinary flow rate, and sodium and potassium excretions (+226, +307 and +171 p. 100, respectively).	Potassium	121-130	natriuretic peptide A	Homo sapiens	24-27
3163923-0	1988	Phorbol esters stimulate the potassium-induced release of cholecystokinin from slices of cerebral cortex, caudato-putamen and hippocampus incubated in vitro.	Potassium	29-38	cholecystokinin	Homo sapiens	58-73
2837695-1	1988	Interactions between cholecystokinin (CCK) and noradrenaline (NA) have been studied by investigating the effect of sulphated cholecystokinin octapeptide (CCK-8) on potassium (K+)-stimulated release of [3H]NA from superfused hypothalamic slices.	Potassium	164-173	cholecystokinin	Homo sapiens	154-157
3135432-2	1988	Eighteen of 26 patients with newly diagnosed KS were treated continuously with IFN until progression of the disease occurred.	Potassium	45-47	interferon alpha 1	Homo sapiens	79-82
3135432-10	1988	Our results indicate that only a small portion of AIDS patients with KS seem to benefit from a continuous treatment with IFN.	Potassium	69-71	interferon alpha 1	Homo sapiens	121-124
2456821-2	1988	Both the release of somatostatin and the increase in cyclic AMP elicited by VIP require exogenous calcium, can be blocked by cobalt ion, and can be qualitatively mimicked by depolarizating concentrations of exogenous potassium ion.	Potassium	217-226	somatostatin	Homo sapiens	20-32
2456821-2	1988	Both the release of somatostatin and the increase in cyclic AMP elicited by VIP require exogenous calcium, can be blocked by cobalt ion, and can be qualitatively mimicked by depolarizating concentrations of exogenous potassium ion.	Potassium	217-226	vasoactive intestinal peptide	Homo sapiens	76-79
2898958-6	1988	2-Amino-5-phosphonovaleric acid (APV), 2-amino-7-phosphonoheptanoic acid (APH) and MK-801 all reduced the potassium-evoked efflux of aspartate and glutamate by between 14.9% and 34.3% (P less than 0.05).	Potassium	106-115	acylaminoacyl-peptide hydrolase	Rattus norvegicus	74-77
3393274-4	1988	Following unilateral application of a depolarizing concentration of potassium ions, there was a large, sustained, calcium-dependent increase in release of acetylcholinesterase, specifically in the local cerebellar cortex; a marked enhancement of acetylcholinesterase release also occurred in the contralateral cerebellum, suggesting that the phenomenon reflected polysynaptic neuronal events.	Potassium	68-77	acetylcholinesterase	Cavia porcellus	155-175
3260662-3	1988	Microinfusion of either potassium or amphetamine into the substantia nigra caused an increase in the local release of acetylcholinesterase.	Potassium	24-33	acetylcholinesterase	Cavia porcellus	118-138
2898368-0	1988	Decrease of plasma potassium due to inhalation of beta-2-agonists: absence of an additional effect of intravenous theophylline.	Potassium	19-28	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	50-56
2898368-1	1988	The effect on the plasma potassium concentration of inhalation of the beta-2-agonists fenoterol, salbutamol (albuterol), and terbutaline from metered-dose inhalers was studied in normal volunteers.	Potassium	25-34	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	70-76
3393274-4	1988	Following unilateral application of a depolarizing concentration of potassium ions, there was a large, sustained, calcium-dependent increase in release of acetylcholinesterase, specifically in the local cerebellar cortex; a marked enhancement of acetylcholinesterase release also occurred in the contralateral cerebellum, suggesting that the phenomenon reflected polysynaptic neuronal events.	Potassium	68-77	acetylcholinesterase	Cavia porcellus	246-266
2457967-1	1988	The early changes in potassium fluxes in PHA-treated human lymphocytes were studied.	Potassium	21-30	lamin B receptor	Homo sapiens	41-44
2896064-0	1988	A potassium conductance contributes to the action of somatostatin-14 to suppress ACTH secretion.	Potassium	2-11	pro-opiomelanocortin-alpha	Mus musculus	81-85
3378057-0	1988	Rat liver gamma-butyrobetaine hydroxylase catalyzed reaction: influence of potassium, substrates, and substrate analogues on hydroxylation and decarboxylation.	Potassium	75-84	gamma-butyrobetaine hydroxylase 1	Rattus norvegicus	10-41
3378057-2	1988	Potassium ion stimulates rat liver gamma-butyrobetaine hydroxylase catalyzed L-carnitine synthesis and alpha-ketoglutarate decarboxylation by 630% and 240%, respectively, and optimizes the coupling efficiency of these two activities.	Potassium	0-9	gamma-butyrobetaine hydroxylase 1	Rattus norvegicus	35-66
2965959-3	1988	In 13 (87%) of 15 SFO neurons, ANP at 10(-7) M depressed by more than 40% the excitation induced by AII at 10(-7) M, while ANP did not always depress the excitation induced by raising the extracellular potassium concentrations in 6 SFO cells tested.	Potassium	202-211	natriuretic peptide A	Rattus norvegicus	31-34
3392667-6	1988	Enkephalin hyperpolarized interneurones, most probably by increasing potassium conductance; this action was blocked by the opiate antagonist, naloxone.	Potassium	69-78	proenkephalin	Rattus norvegicus	0-10
3392681-19	1988	In every case where pHi decreased, the changes in membrane potential and conductance could be explained largely on the basis of a decrease in potassium permeability.	Potassium	142-151	glucose-6-phosphate isomerase	Rattus norvegicus	20-23
3277570-3	1988	Liver and muscles represent the major buffering system, partially mediated by insulin, in the distribution of potassium between intracellular and extracellular fluids.	Potassium	110-119	insulin	Homo sapiens	78-85
2457967-2	1988	The increase in both ouabain-sensitive potassium influx and ouabain-resistant potassium efflux at the optimal mitogenic concentration of PHA was observed.	Potassium	39-48	lamin B receptor	Homo sapiens	137-140
2457967-2	1988	The increase in both ouabain-sensitive potassium influx and ouabain-resistant potassium efflux at the optimal mitogenic concentration of PHA was observed.	Potassium	78-87	lamin B receptor	Homo sapiens	137-140
3277011-1	1988	The ability of insulin to promote extrarenal potassium uptake and to stimulate glucose uptake was examined in eight obese and ten normal weight control subjects.	Potassium	45-54	insulin	Homo sapiens	15-22
3127518-0	1988	Diurnal variation in the effect of potassium depolarization on vasoactive intestinal polypeptide release from rat hypothalamus: a possible role for adrenaline.	Potassium	35-44	vasoactive intestinal peptide	Rattus norvegicus	63-96
3348415-0	1988	Parathyroid hormone impairs extrarenal potassium tolerance in the rat.	Potassium	39-48	parathyroid hormone	Rattus norvegicus	0-19
3277011-3	1988	Insulin-mediated potassium, as well as glucose uptake, was diminished during the lowest dose insulin clamp study (100 microU/mL) but could be normalized at pharmacologic plasma insulin concentrations.	Potassium	17-26	insulin	Homo sapiens	0-7
3277011-3	1988	Insulin-mediated potassium, as well as glucose uptake, was diminished during the lowest dose insulin clamp study (100 microU/mL) but could be normalized at pharmacologic plasma insulin concentrations.	Potassium	17-26	insulin	Homo sapiens	93-100
3277011-4	1988	These results indicate that obese subjects are resistant to the ability of insulin to stimulate potassium uptake by extrarenal tissues.	Potassium	96-105	insulin	Homo sapiens	75-82
3277011-5	1988	Impaired potassium uptake at physiologic plasma insulin levels, with normalization at supraphysiologic insulin concentrations, is most consistent with a decrease in the number of insulin receptors on insulin target tissues.	Potassium	9-18	insulin	Homo sapiens	48-55
3277011-5	1988	Impaired potassium uptake at physiologic plasma insulin levels, with normalization at supraphysiologic insulin concentrations, is most consistent with a decrease in the number of insulin receptors on insulin target tissues.	Potassium	9-18	insulin	Homo sapiens	103-110
3277011-5	1988	Impaired potassium uptake at physiologic plasma insulin levels, with normalization at supraphysiologic insulin concentrations, is most consistent with a decrease in the number of insulin receptors on insulin target tissues.	Potassium	9-18	insulin	Homo sapiens	103-110
3277011-5	1988	Impaired potassium uptake at physiologic plasma insulin levels, with normalization at supraphysiologic insulin concentrations, is most consistent with a decrease in the number of insulin receptors on insulin target tissues.	Potassium	9-18	insulin	Homo sapiens	103-110
3138095-4	1988	The infusion of insulin in association with potassium ions induced a similar but less sustained effect.	Potassium	44-53	insulin	Oryctolagus cuniculus	16-23
3075149-3	1988	Insulin without affecting the filtration rate of creatinine and the urine flow rate resulted in significant increases in urinary calcium (3.56 +/- 0.80 vs. 7.48 +/- 0.80 mumol/min/1.73 m2) and magnesium (2.44 +/- 0.41 vs. 4.29 +/- 0.5 mumol/min/1.73 m2) and a fall in potassium excretion (53.25 +/- 13.17 vs. 23.71 +/- 4.21 mumol/min/1.73 m2).	Potassium	268-277	insulin	Homo sapiens	0-7
2892268-3	1988	Both somatostatin-28 and somatostatin-14 elicited a steady outward current and selectively augmented the noninactivating, voltage-dependent outward potassium current known as the M-current.	Potassium	148-157	somatostatin	Homo sapiens	5-20
2892268-3	1988	Both somatostatin-28 and somatostatin-14 elicited a steady outward current and selectively augmented the noninactivating, voltage-dependent outward potassium current known as the M-current.	Potassium	148-157	somatostatin	Homo sapiens	25-40
2891695-2	1988	An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin.	Potassium	15-24	somatostatin	Rattus norvegicus	142-154
2891696-2	1988	An increase in potassium conductance initiates somatostatin-induced inhibition of prolactin secretion.	Potassium	15-24	prolactin	Rattus norvegicus	82-91
2455613-1	1988	The effects of insulin on sodium and potassium metabolism have been well known for many years; clinical observation and laboratory experience showed different results about the insulin effect on the sodium-potassium pump.	Potassium	37-46	insulin	Homo sapiens	15-22
3345680-0	1988	Gastrin stimulates intestinal potassium absorption.	Potassium	30-39	gastrin	Homo sapiens	0-7
2448701-2	1988	Treatment of the cells with potassium (20 mM) or veratridine (10 microM) for 12, 24 and 48 h caused a time-dependent increase in the levels of POMC mRNA which became significant after 24 h. These effects were not seen in the presence of the sodium channel blocker tetrodotoxin (5 microM).	Potassium	28-37	pro-opiomelanocortin-alpha	Mus musculus	143-147
2838285-1	1988	Since the serum potassium level is under beta 2-adrenergic influence, we studied serum potassium values on admission in psychiatric patients.	Potassium	16-25	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	41-47
2465934-6	1988	Both phasic and tonic components of the vas deferens response to potassium were markedly dependent upon external calcium ions.	Potassium	65-74	arginine vasopressin	Rattus norvegicus	40-43
2829046-5	1988	Depolarizing concentrations of potassium in the presence of calcium stimulated significant increments in release of IR-ACTH/IR-beta-endorphin by amygdala (111/105%) and cortical (162/136%) cells.	Potassium	31-40	proopiomelanocortin	Homo sapiens	127-141
2835702-5	1988	VIP alone failed to evoke catecholamine secretion from chromaffin cells, but potentiated potassium-, veratridine-, and nicotine-evoked secretion.	Potassium	89-98	vasoactive intestinal peptide	Bos taurus	0-3
3149791-8	1988	These results suggest that hCG stimulation involved the blockade of a potassium current and the activation of a chloride current through an increase of intracellular calcium.	Potassium	70-79	hypertrichosis 2 (generalised, congenital)	Homo sapiens	27-30
2977004-6	1988	Potassium ions produced a further activation of the Zn2+-dependent ATPase system by about 10%.	Potassium	0-9	dynein axonemal heavy chain 8	Homo sapiens	67-73
2850631-5	1988	NPY was also seen to decrease the potassium-induced release of norepinephrine (NE) from slices obtained from the posterior hypothalamic nucleus.	Potassium	34-43	neuropeptide Y	Rattus norvegicus	0-3
2447792-0	1987	Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes.	Potassium	43-52	calmodulin	Bos taurus	0-10
3062959-5	1988	ACE-inhibition also prevents secondary aldosteronism and thereby avoids renal potassium loss.	Potassium	78-87	angiotensin I converting enzyme	Homo sapiens	0-3
3062959-6	1988	The initial positive potassium balance after ACE-inhibition may protect patients with heart disease from potentially hazardous arrhythmias.	Potassium	21-30	angiotensin I converting enzyme	Homo sapiens	45-48
3691807-1	1987	It is shown that the salt effect in acetylcholinesterase-catalyzed hydrolysis of 2-(N-methylmorpholinium)-ethylacetate can be quantitatively described by the equation log(k2/KS) = log(k2/KS) degrees--psi log[M+Z] following from Manning"s polyelectrolyte theory; the psi values for salts with univalent and bivalent cations at different pH values of the reaction medium were in accordance with the conclusions of the theory.	Potassium	174-176	acetylcholinesterase (Cartwright blood group)	Homo sapiens	36-56
2834698-7	1988	Acetylcholine at 50 microM and high potassium stimulated fetal adrenal VIP release while norepinephrine did not.	Potassium	36-45	vasoactive intestinal peptide	Homo sapiens	71-74
2961879-5	1987	ANP treatment resulted in a significant peak increase in sodium (5.6-fold), lithium (2.1-fold), potassium (2.3-fold) and water (5.1-fold) excretion.	Potassium	96-105	natriuretic peptide A	Rattus norvegicus	0-3
3325393-4	1987	Recently, controlled studies have shown that the introduction and supplementation of therapeutic regimens with ACE inhibitions and specifically captopril is associated with substantial clinical benefits: Symptoms are reduced as hemodynamics and exercise capacity improve, metabolic derangements (including fluid retention, potassium and magnesium loss and sympathetic nervous activation) are reduced with resultant favourable effects on arrhythmia frequency and finally the newest and most dramatic observation of improved survival.	Potassium	323-332	angiotensin I converting enzyme	Homo sapiens	111-114
3325394-4	1987	The antihypertensive effect of ACE inhibitors is characterized by some particularly favorable features: ACE inhibitors attenuate the fall in serum potassium and the rise in plasma uric acid induced by diuretics, they do not cause any salt retention nor orthostatic hypotension, they do not raise pulse rate when they reduce blood pressure, and they certainly do not reduce the perfusion rate of the brain, the heart or the kidneys.	Potassium	147-156	angiotensin I converting enzyme	Homo sapiens	31-34
3325394-4	1987	The antihypertensive effect of ACE inhibitors is characterized by some particularly favorable features: ACE inhibitors attenuate the fall in serum potassium and the rise in plasma uric acid induced by diuretics, they do not cause any salt retention nor orthostatic hypotension, they do not raise pulse rate when they reduce blood pressure, and they certainly do not reduce the perfusion rate of the brain, the heart or the kidneys.	Potassium	147-156	angiotensin I converting enzyme	Homo sapiens	104-107
2965232-6	1987	In contrast to that of sodium, potassium excretion and urinary volume remained significantly below baseline levels when ANP was administered against a background infusion of ANG II.	Potassium	31-40	natriuretic peptide A	Homo sapiens	120-123
3439594-0	1987	[Involvement of the growth hormone in rapid increases of the potassium concentration of the serum].	Potassium	61-70	growth hormone 1	Homo sapiens	20-34
3439594-2	1987	The investigation is concerned with the short-term effect of growth hormone, which can be stimulated by arginine (0.6 g/kg body weight), on potassium concentrations in rats and patients with cerebral death.	Potassium	140-149	gonadotropin releasing hormone receptor	Rattus norvegicus	61-75
3439594-3	1987	The administration of human somatotropin causes a significant rise in potassium concentrations in patients with cerebral death (0.4 IU/kg body weight) and in rats (4.0 IU/kg body weight).	Potassium	70-79	growth hormone 1	Homo sapiens	28-40
3447811-3	1987	One group received 20 mmol/l potassium chloride in the dextrose infusate, calculated to replace the extracellular potassium deficit due to the action of insulin on potassium flux.	Potassium	29-38	insulin	Homo sapiens	153-160
3447811-4	1987	Despite this, serum potassium fell equally in both groups in response to each level of insulin infusion.	Potassium	20-29	insulin	Homo sapiens	87-94
2445917-1	1987	The binding and internalization of 125I-nerve growth factor (NGF) by PC12 pheochromocytoma cells was studied as a function of extracellular potassium concentration.	Potassium	140-149	nerve growth factor	Rattus norvegicus	35-59
2444358-8	1987	Addition of bradykinin (100 nM) elicited a calcium-activated potassium current that was eliminated in the absence of intracellular potassium.	Potassium	61-70	kininogen 1	Bos taurus	12-22
3673912-5	1987	These results with a hypertonic glucose infusion are similar to those reported after infusion of glucose-insulin-potassium without the potential for harmful adverse effects from infusions of insulin or potassium.	Potassium	113-122	insulin	Homo sapiens	105-112
3312441-7	1987	Stimulation of renin release may likewise be related either to decreased chloride delivery and hence decreased transport in the loop (hypochloremia related to selective chloride deprivation) or to an intrinsic alteration in the transporting capacity of the loop (loop diuretics, potassium depletion, glucocorticoid deficiency, Bartter"s syndrome).	Potassium	279-288	renin	Homo sapiens	15-20
2824980-3	1987	Tolerance to the opioid-induced increase in potassium conductance was observed, and this was more pronounced for normorphine than for [Met5]enkephalin and [D-Ala2, Mephe4, Gly5-ol]enkephalin: experiments with the irreversible receptor blocker beta-chlornaltrexamine indicated that normorphine had lower intrinsic efficacy than [Met5]enkephalin and [D-Ala2 MePhe4, Gly5-ol]enkephalin.	Potassium	44-53	proenkephalin	Rattus norvegicus	140-150
2824980-3	1987	Tolerance to the opioid-induced increase in potassium conductance was observed, and this was more pronounced for normorphine than for [Met5]enkephalin and [D-Ala2, Mephe4, Gly5-ol]enkephalin: experiments with the irreversible receptor blocker beta-chlornaltrexamine indicated that normorphine had lower intrinsic efficacy than [Met5]enkephalin and [D-Ala2 MePhe4, Gly5-ol]enkephalin.	Potassium	44-53	proenkephalin	Rattus norvegicus	180-190
2824980-3	1987	Tolerance to the opioid-induced increase in potassium conductance was observed, and this was more pronounced for normorphine than for [Met5]enkephalin and [D-Ala2, Mephe4, Gly5-ol]enkephalin: experiments with the irreversible receptor blocker beta-chlornaltrexamine indicated that normorphine had lower intrinsic efficacy than [Met5]enkephalin and [D-Ala2 MePhe4, Gly5-ol]enkephalin.	Potassium	44-53	proenkephalin	Rattus norvegicus	180-190
2824980-3	1987	Tolerance to the opioid-induced increase in potassium conductance was observed, and this was more pronounced for normorphine than for [Met5]enkephalin and [D-Ala2, Mephe4, Gly5-ol]enkephalin: experiments with the irreversible receptor blocker beta-chlornaltrexamine indicated that normorphine had lower intrinsic efficacy than [Met5]enkephalin and [D-Ala2 MePhe4, Gly5-ol]enkephalin.	Potassium	44-53	proenkephalin	Rattus norvegicus	180-190
3667589-0	1987	Potassium depletion selectively inhibits sustained diacylglycerol formation from phosphatidylinositol in angiotensin II-stimulated, cultured vascular smooth muscle cells.	Potassium	0-9	angiotensinogen	Rattus norvegicus	105-119
3667589-1	1987	Potassium depletion decreases blood pressure in vivo and blunts the pressor response to angiotensin II (ang II) without down-regulating the receptor.	Potassium	0-9	angiotensinogen	Rattus norvegicus	88-110
3667589-6	1987	Together with its marked inhibitory effect on sustained ang II-induced DG formation, acute potassium depletion effectively blocks internalization of 125I-ang II: there is no significant internalization of the ligand after 5 min at 37 degrees C versus 64 +/- 7% internalization in control cells.	Potassium	91-100	angiotensinogen	Rattus norvegicus	154-160
3668538-1	1987	Angiotensin II (ANGII) (3-100 nM) facilitated the potassium-evoked (22.5 mM) release of [3H]-noradrenaline ([3H]NA) from slices of parietal cortex in a concentration-dependent manner, but did not significantly alter the release of [3H]NA evoked in a similar manner from locus coeruleus slices.	Potassium	50-59	angiotensinogen	Rattus norvegicus	0-14
3668538-1	1987	Angiotensin II (ANGII) (3-100 nM) facilitated the potassium-evoked (22.5 mM) release of [3H]-noradrenaline ([3H]NA) from slices of parietal cortex in a concentration-dependent manner, but did not significantly alter the release of [3H]NA evoked in a similar manner from locus coeruleus slices.	Potassium	50-59	angiotensinogen	Rattus norvegicus	16-21
2893595-3	1987	Potassium induced during these conditions a small contraction whose magnitude was attenuated by raised concentrations of Mg2+ (4.4 and 13.2 mM).	Potassium	0-9	mucin 7, secreted	Homo sapiens	121-124
3323013-5	1987	Infusion of insulin in this Series elicited smaller decrease in plasma potassium concentration and longer lasting hypernatremia than in dogs in water-electrolytes balance.	Potassium	71-80	insulin	Canis lupus familiaris	12-19
3323013-7	1987	Infusion of insulin in Series 1 elicited increase of sodium excretion and decrease in potassium excretion.	Potassium	86-95	insulin	Canis lupus familiaris	12-19
3323013-9	1987	The results indicate that depletion of electrolytes and blood aldosterone elevation modify the effects of insulin on plasma concentration and renal excretion of sodium and potassium.	Potassium	172-181	insulin	Canis lupus familiaris	106-113
2448491-5	1987	Beta 1-adrenoceptors increase contraction and calcium current, and shorten action potential duration (APD) by increasing potassium conductance.	Potassium	121-130	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	0-6
3443953-10	1987	There was a significant negative correlation between the serum albumin concentration and the ratio of potassium to sodium ions in milk samples obtained from rats milked with varying oxytocin treatments.	Potassium	102-111	albumin	Rattus norvegicus	57-70
2825054-0	1987	Induction of the high-affinity nerve growth factor receptor on embryonic chicken sensory nerve cells by elevated potassium.	Potassium	113-122	neurotrophic receptor tyrosine kinase 1	Gallus gallus	17-59
3299096-9	1987	We conclude that this insulin resistance involves glucose but not lipid or potassium metabolism, is located in peripheral tissues but not the liver, is limited to nonoxidative pathways of intracellular glucose disposal, and is directly correlated with the severity of hypertension.	Potassium	75-84	insulin	Homo sapiens	22-29
3311097-8	1987	Activation of the renin-angiotensin-aldosterone system was, however, related to hypokalaemia and potassium depletion.	Potassium	97-106	renin	Homo sapiens	18-23
2823961-3	1987	Orthodromic spike activity of CA1 pyramidal cells and field excitatory postsynaptic potentials (f-EPSPs) failed rapidly after anoxia with little change in potassium ion activity and without failure of the Schaffer collateral prevolley or antidromic responses of pyramidal cells.	Potassium	155-164	carbonic anhydrase 1	Homo sapiens	30-33
3653348-8	1987	In vitro, I-3-C was found to be a type II ligand for cytochrome P-450, with a Ks value of 237 microM.	Potassium	78-80	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	53-69
2450994-0	1987	Somatostatin increases an inwardly rectifying potassium conductance in guinea-pig submucous plexus neurones.	Potassium	46-55	somatostatin	Cavia porcellus	0-12
2450994-11	1987	A potassium conductance with the same properties was increased by alpha 2-adrenoceptor agonists and by delta-opioid receptor agonists; however, the effects of somatostatin were unaffected by antagonists at alpha 2- or delta-receptors.	Potassium	2-11	somatostatin	Cavia porcellus	159-171
2957062-6	1987	Thus one of the mRNAs transcribed from the KS oncogene encodes a growth factor that could transform cells by an autocrine mechanism and appears to represent a new member of the FGF family.	Potassium	43-45	fibroblast growth factor 4	Mus musculus	177-180
3611549-9	1987	An 8-fl oz serving of whole milk is an excellent source of iodine, calcium, phosphorus, and potassium.	Potassium	92-101	Weaning weight-maternal milk	Bos taurus	28-32
2445661-7	1987	These results show that the drugs interact differently with the different cell populations involved in T cell proliferation: increase of an amiloride-dependent sodium influx is an obligatory step required to induce the early increase of the ouabain-dependent potassium influx which is needed for the expression of IL 2 receptors.	Potassium	259-268	interleukin 2	Homo sapiens	314-318
2445661-8	1987	On the contrary, the influx of potassium necessary for the IL 2-dependent proliferation does not seem to be controlled by the amiloride-dependent sodium flux.	Potassium	31-40	interleukin 2	Homo sapiens	59-63
2821083-0	1987	Impairment of beta 2-adrenoceptor-stimulated potassium uptake in end-stage renal disease.	Potassium	45-54	adrenoceptor beta 2	Homo sapiens	14-33
2821083-5	1987	Furthermore, the final plasma potassium concentration slightly exceeded baseline in the patients but was significantly reduced in controls, leading to the conclusion that an abnormal responsiveness of the beta 2 adrenoceptor may contribute to the impaired potassium tolerance found in patients who have end-stage renal disease.	Potassium	30-39	adrenoceptor beta 2	Homo sapiens	205-224
2821083-5	1987	Furthermore, the final plasma potassium concentration slightly exceeded baseline in the patients but was significantly reduced in controls, leading to the conclusion that an abnormal responsiveness of the beta 2 adrenoceptor may contribute to the impaired potassium tolerance found in patients who have end-stage renal disease.	Potassium	256-265	adrenoceptor beta 2	Homo sapiens	205-224
3655875-0	1987	Activity-evoked increases in extracellular potassium modulate presynaptic excitability in the CA1 region of the hippocampus.	Potassium	43-52	carbonic anhydrase 1	Rattus norvegicus	94-97
3655875-12	1987	Concomitant with changes in the excitability of CA1 afferents, the concentration of extracellular potassium ( [K+]o) increased up to 7 mM, as recorded in the stratum radiatum with potassium ion-sensitive microelectrodes.	Potassium	98-107	carbonic anhydrase 1	Rattus norvegicus	48-51
3655875-12	1987	Concomitant with changes in the excitability of CA1 afferents, the concentration of extracellular potassium ( [K+]o) increased up to 7 mM, as recorded in the stratum radiatum with potassium ion-sensitive microelectrodes.	Potassium	180-189	carbonic anhydrase 1	Rattus norvegicus	48-51
2443822-0	1987	Arteriolar resistance and plasma [K+] increases produced by angiotensin II: The implications of potassium-induced depressor responses.	Potassium	96-105	angiotensinogen	Homo sapiens	60-74
3680022-4	1987	On the other hand, basal activity (the activity in the presence of ethylene bis(oxyethylenenitrilo)tetraacetic acid (EGTA) instead of Ca2+/calmodulin) of the bovine brain enzyme, calmodulin-independent cyclic nucleotide phosphodiesterase from bovine heart, and protein kinase C from rat brain were inhibited by KS-619-1 to a lesser extent with IC50 values; 12.3, 25.9 and 151 microM, respectively.	Potassium	311-313	calmodulin	Bos taurus	179-189
3680023-1	1987	The structure of KS-619-1, a potent inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase, was determined to be 8,13-dioxo-3-(2-oxopropyl)-5,6,8,13-tetrahydro-1,7,9,11- tetrahydroxybenz[a]naphtacene-2-carboxylic acid by spectral studies of KS-619-1 and its methyl derivative.	Potassium	17-19	calmodulin 1	Homo sapiens	58-68
2442708-3	1987	In contrast, 3,4-diaminopyridine (3,4-DAP) reduced the fast potassium current without affecting the inactivation.	Potassium	60-69	death associated protein	Gallus gallus	38-41
3680022-3	1987	IC50 values for the effect of KS-619-1 on Ca2+ and calmodulin-stimulated activity of bovine brain and heart enzymes were 2.0 and 1.5 microM, respectively.	Potassium	30-32	calmodulin	Bos taurus	51-61
3037891-5	1987	Moreover, increased levels of angiotensin II cause heightened sympathetic nervous activity, potassium depletion, and hyponatremia, each of which can lead to further clinical deterioration.	Potassium	92-101	angiotensinogen	Homo sapiens	30-44
2956945-1	1987	The effect of barium and potassium on the secretion and biosynthesis of enkephalin in bovine chromaffin cells, and prolactin and beta-endorphin in rat anterior pituitary cells, was examined to determine whether calcium-dependent secretion and biosynthesis are mediated by the same or by different calcium targets within the neuroendocrine cell.	Potassium	25-34	proenkephalin	Rattus norvegicus	72-82
2956945-2	1987	In the presence of 1.8 mM calcium, barium and potassium stimulated the secretion of all three peptides over 30 min, and increased the levels of proenkephalin and prolactin mRNA in 24 hr.	Potassium	46-55	prolactin	Rattus norvegicus	162-171
2956945-5	1987	On the other hand, stimulation of proenkephalin and prolactin mRNA by both potassium and barium was inhibited when the extracellular calcium concentration was reduced.	Potassium	75-84	prolactin	Bos taurus	52-61
2887177-6	1987	Potassium-stimulated, Ca2+-dependent release of [3H]glutamate was significantly greater in slices of dentate gyrus and area CA1 prepared from conditioned animals than from pseudoconditioned animals.	Potassium	0-9	carbonic anhydrase 2	Rattus norvegicus	22-25
2887177-6	1987	Potassium-stimulated, Ca2+-dependent release of [3H]glutamate was significantly greater in slices of dentate gyrus and area CA1 prepared from conditioned animals than from pseudoconditioned animals.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	124-127
3436102-0	1987	Increases in urinary kallikrein activity and prostanoid synthesis after dietary potassium supplementation.	Potassium	80-89	kallikrein related peptidase 4	Homo sapiens	21-31
2891811-4	1987	CIM gave type II difference spectra with dissociation constants (Ks) of 10.4 and 111 microM while ROX gave reverse type I difference spectra with Ks of 55.6 microM.	Potassium	146-148	ribosomal oxygenase 2	Homo sapiens	98-101
2439125-1	1987	Recent evidence proposes that the calcium-binding protein, calmodulin, plays a crucial role in the regulation or modulation of the calcium-dependent potassium conductance in Paramecium tetraurelia (Hinrichsen, R.D., Burgess-Cassler, A., Soltvedt, B.C., Hennessey, T. and Kung, C. (1986) Science 323, 503-506).	Potassium	149-158	calmodulin	Bos taurus	59-69
2955951-4	1987	A greater change in circulating atrial natriuretic factor (96 +/- 12 pg/ml) was required to significantly decrease right atrial pressure, cardiac output, and plasma renin activity, and to increase systemic vascular resistance and total and fractional excretion of potassium.	Potassium	264-273	natriuretic peptide A	Canis lupus familiaris	32-57
3436102-5	1987	Significant increases in urinary kallikrein excretion (P less than 0.01), and urinary 6-keto-PGF1 alpha (P less than 0.01) were observed during potassium supplementation.	Potassium	144-153	kallikrein related peptidase 4	Homo sapiens	33-43
3436102-10	1987	Enhanced kallikrein/kinin and prostacyclin formation could contribute to the blood pressure lowering effect of potassium reported in hypertensive subjects.	Potassium	111-120	kallikrein related peptidase 4	Homo sapiens	9-19
2441001-13	1987	Intracellular injection of ethyleneglycol-bis-(beta-aminoethylether)-N,N"-tetraacetic acid or extracellular application of forskolin, procedures known to reduce or block certain calcium-dependent potassium conductances in CA3 neurons, had no significant effect on the late IPSP.	Potassium	196-205	carbonic anhydrase 3	Rattus norvegicus	222-225
3037891-8	1987	Angiotensin II plays an important role in preserving systemic BP and in preserving the glomerular filtration rate as renal artery pressure and renal blood flow decline; in addition, by stimulating the synthesis of aldosterone, the renin-angiotensin system provides an important role for potassium disposal.	Potassium	287-296	angiotensinogen	Homo sapiens	0-14
3037891-8	1987	Angiotensin II plays an important role in preserving systemic BP and in preserving the glomerular filtration rate as renal artery pressure and renal blood flow decline; in addition, by stimulating the synthesis of aldosterone, the renin-angiotensin system provides an important role for potassium disposal.	Potassium	287-296	renin	Homo sapiens	231-236
3607476-6	1987	Depolarizing agents such as potassium (50 mM) and veratridine (50 microM), which is known to increase Na+ conductance, significantly stimulated alpha-MSH release in a Ca2+-dependent manner.	Potassium	28-37	proopiomelanocortin	Rattus norvegicus	144-153
3038270-0	1987	Lithium preincubation stimulates the potassium-induced release of cholecystokinin from slices of cerebral cortex and caudate-putamen incubated in vitro.	Potassium	37-46	cholecystokinin	Homo sapiens	66-81
3038270-1	1987	Potassium-evoked cholecystokinin (CCK) release from slices of caudate-putamen and cerebral cortex, but not hippocampus incubated in vitro was increased by 152-175% by preincubation for 40 min with 10 mM lithium.	Potassium	0-9	cholecystokinin	Homo sapiens	17-32
3038270-1	1987	Potassium-evoked cholecystokinin (CCK) release from slices of caudate-putamen and cerebral cortex, but not hippocampus incubated in vitro was increased by 152-175% by preincubation for 40 min with 10 mM lithium.	Potassium	0-9	cholecystokinin	Homo sapiens	34-37
2439348-10	1987	These results suggest immediate alteration in membrane structure upon CsA treatment, causing potassium leakage and calcium ion uptake.	Potassium	93-102	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	70-73
3591961-0	1987	Effect of vasopressin analogue (dDAVP) on potassium transport in medullary collecting duct.	Potassium	42-51	arginine vasopressin	Rattus norvegicus	10-21
3035942-2	1987	Exposure of isolated toad bladders to quinidine, calcium ionophores (A23187, X537A), or low-sodium or potassium-free serosal solutions resulted in a dose-dependent decrease in the hydrosmotic response to vasopressin or exogenous adenosine 3",5"-cyclic monophosphate (cAMP).	Potassium	102-111	arginine vasopressin	Homo sapiens	204-215
2884609-2	1987	Methionine (Met)-enkephalin did not affect the extracellular potassium level at rest but suppressed the potassium response elicited by afferent volleys.	Potassium	104-113	proenkephalin	Rattus norvegicus	17-27
3294899-3	1987	At the lowest insulin level, the Michaelis constants (Ks:s) for glucose disposal in whole body (8.7 +/- 1.1 mM) and across forearm (7.4 +/- 1.4) mM) were compatible with a Ks determined in vitro for the transport system.	Potassium	54-56	insulin	Homo sapiens	14-21
3294899-4	1987	At higher insulin levels, the apparent Ks increased significantly in whole body (16.2-37.7 mM) and across forearm (20.7-31.2 mM).	Potassium	39-41	insulin	Homo sapiens	10-17
3294899-5	1987	We interpret the apparent increase of Ks by insulin to reflect a shift in the rate-limiting step from glucose transport to some step beyond transport.	Potassium	38-40	insulin	Homo sapiens	44-51
2439680-4	1987	Bay K 8644 caused a leftward shift of the dose-response curve of the potassium-induced decrease in renin release.	Potassium	69-78	renin	Rattus norvegicus	99-104
2953719-2	1987	The K+-ATPase of Streptococcus faecalis consists of a single polypeptide component of relative Mr = 78,000 and serves as an ATP-driven pump for the accumulation of potassium by the bacterial cell.	Potassium	164-173	ATPase	Enterococcus faecalis	7-13
3111527-6	1987	The conformational changes induced in S100b by interaction with melittin increased its affinity for calcium and offset the inhibition of calcium binding otherwise observed in the presence of potassium ions.	Potassium	191-200	S100 calcium binding protein B	Homo sapiens	38-43
2884609-4	1987	In the chronically deafferent spinal cord combined with the block of synaptic transmission by Mg2+, Met-enkephalin suppressed the transient rise of the extracellular potassium concentration induced by L-glutamate.	Potassium	166-175	proenkephalin	Rattus norvegicus	104-114
2886317-9	1987	When highly purified forms of P-450, including P-450 2, 3b, 3c, and 4, were assayed in a reconstituted system, only P-450 3c exhibited type I binding spectrum upon CsA addition (Ks = 1.4 +/- 0.5 microM) and extensively metabolized the drug to all derivatives.	Potassium	178-180	cytochrome P450 3A6	Oryctolagus cuniculus	116-124
2953624-2	1987	ANF caused a concentration-dependent relaxation in arterial strips submaximally precontracted with noradrenaline, 5-hydroxytryptamine, or high-potassium solution (10-30 mM).	Potassium	143-152	natriuretic peptide A	Canis lupus familiaris	0-3
2437260-1	1987	Mutations of the Shaker (Sh) locus alter or eliminate a transient, voltage-sensitive potassium current, the "A" current, in flight muscle of Drosophila.	Potassium	85-94	Shaker	Drosophila melanogaster	17-23
3035049-0	1987	Role of potassium in vasopressin-induced production of cyclic AMP in rat renal papillary collecting tubule cells in culture.	Potassium	8-17	arginine vasopressin	Rattus norvegicus	21-32
3035049-1	1987	The effect of potassium (K)-free medium on the stimulation of cyclic AMP (cAMP) production by arginine vasopressin (AVP) and forskolin was examined in rat renal papillary collecting tubule cells in culture.	Potassium	14-23	arginine vasopressin	Rattus norvegicus	103-114
3614001-4	1987	Brennan et al (Life Sciences 27: 1097-1101, 1980) reported a greater percent inhibition of potassium-stimulated GABA release with increasing concentrations of met-enkephalin.	Potassium	91-100	proopiomelanocortin	Homo sapiens	159-173
3296457-3	1987	Treatment with parenteral insulin alone resulted in a decrease of the serum glucose value from 41 +/- 14 (standard deviation) to 11 +/- 5 mmol per liter (P &lt;.001) and of serum potassium level from 5.2 +/- 1.2 to 4.0 +/- 0.6 mmol per liter (P &lt;.001).	Potassium	179-188	insulin	Homo sapiens	26-33
2883866-2	1987	Selective beta 2-adrenoceptor activation by salbutamol failed to alter myocardia excitability but significantly lowered serum potassium concentration.	Potassium	126-135	beta-2 adrenergic receptor	Canis lupus familiaris	10-29
3472234-9	1987	Potassium transport is accelerated at low pHi, but in a manner consistent with its inherent voltage sensitivity and changes in Vm resulting from an increased rate of H+ extrusion by the pump.	Potassium	0-9	glucose-6-phosphate isomerase	Homo sapiens	42-45
3827459-8	1987	beta 2-adrenergic stimulation of intracellular potassium uptake by albuterol is a safe and effective alternative for the treatment of hyperkalemia in renal failure.	Potassium	47-56	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	0-6
3036391-11	1987	We conclude that a myocardial potassium uptake ensues during beta 1-adrenoceptor stimulation and adenylate cyclase activation.	Potassium	30-39	adrenoceptor beta 1	Sus scrofa	61-80
3571337-0	1987	Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport.	Potassium	10-19	DNL-type zinc finger	Homo sapiens	33-36
3032992-0	1987	Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses.	Potassium	61-70	DNL-type zinc finger	Homo sapiens	101-104
3032992-1	1987	Potassium depletion after a brief exposure of the cells to hypotonic medium was used to inhibit endocytosis from coated pits in Hep 2 cells.	Potassium	0-9	DNL-type zinc finger	Homo sapiens	128-131
3032992-5	1987	Potassium depletion without hypotonic shock reduced the endocytic uptake of transferrin 2-3-fold and the number of coated pits at the cell surface about 3-fold.	Potassium	0-9	transferrin	Homo sapiens	76-87
3586502-3	1987	After potassium supplementation, plasma potassium, renin, aldosterone or AII, and the relationship between AII and aldosterone levels increased significantly, while body weight, plasma catecholamines, the chronotropic effects of isoproterenol, AII or NE, the pressor effects of AII and plasma clearance of AII or NE were unchanged in all groups.	Potassium	6-15	renin	Homo sapiens	51-56
3586502-3	1987	After potassium supplementation, plasma potassium, renin, aldosterone or AII, and the relationship between AII and aldosterone levels increased significantly, while body weight, plasma catecholamines, the chronotropic effects of isoproterenol, AII or NE, the pressor effects of AII and plasma clearance of AII or NE were unchanged in all groups.	Potassium	6-15	angiotensinogen	Homo sapiens	73-76
3586502-3	1987	After potassium supplementation, plasma potassium, renin, aldosterone or AII, and the relationship between AII and aldosterone levels increased significantly, while body weight, plasma catecholamines, the chronotropic effects of isoproterenol, AII or NE, the pressor effects of AII and plasma clearance of AII or NE were unchanged in all groups.	Potassium	6-15	angiotensinogen	Homo sapiens	107-110
3586502-3	1987	After potassium supplementation, plasma potassium, renin, aldosterone or AII, and the relationship between AII and aldosterone levels increased significantly, while body weight, plasma catecholamines, the chronotropic effects of isoproterenol, AII or NE, the pressor effects of AII and plasma clearance of AII or NE were unchanged in all groups.	Potassium	6-15	angiotensinogen	Homo sapiens	107-110
3586502-3	1987	After potassium supplementation, plasma potassium, renin, aldosterone or AII, and the relationship between AII and aldosterone levels increased significantly, while body weight, plasma catecholamines, the chronotropic effects of isoproterenol, AII or NE, the pressor effects of AII and plasma clearance of AII or NE were unchanged in all groups.	Potassium	6-15	angiotensinogen	Homo sapiens	107-110
3586502-3	1987	After potassium supplementation, plasma potassium, renin, aldosterone or AII, and the relationship between AII and aldosterone levels increased significantly, while body weight, plasma catecholamines, the chronotropic effects of isoproterenol, AII or NE, the pressor effects of AII and plasma clearance of AII or NE were unchanged in all groups.	Potassium	6-15	angiotensinogen	Homo sapiens	107-110
2884011-5	1987	The release of CCK from rat cp slices in vitro stimulated by potassium was quantitated with a specific CCK radioimmunoassay.	Potassium	61-70	cholecystokinin	Rattus norvegicus	15-18
3588257-12	1987	In conclusion, bradykinin hyperpolarizes MDCK-cells by increasing the apparent potassium conductance.	Potassium	79-88	kininogen 1	Canis lupus familiaris	15-25
2884011-6	1987	This potassium-stimulated release of CCK was Ca2+-dependent.	Potassium	5-14	cholecystokinin	Rattus norvegicus	37-40
2884011-7	1987	Maximal stimulation of CCK release was observed at 55 mM potassium.	Potassium	57-66	cholecystokinin	Rattus norvegicus	23-26
3588515-1	1987	The in vitro exposure of rat bronchial smooth muscle to the acetylcholinesterase inhibitor soman (0-[1,1,2-trimethylpropyl]-methylphosphonofluoridate) reduced the potassium (51 mM) evoked release of 3H-acetylcholine (3H-ACh).	Potassium	163-172	acetylcholinesterase	Rattus norvegicus	60-80
3103686-4	1987	The equilibrium dissociation constant, KS, for the interaction between MUGB and urokinase was 2.9 X 10(-6) M, and for the interaction with t-PA 3.13 X 10(-5) M. However, one main requirement for active-site titration, namely a stable acyl enzyme intermediate (ES"), was only fulfilled for MUGB urokinase but not for MUGB t-PA.	Potassium	39-41	plasminogen activator, tissue type	Homo sapiens	139-143
3103686-4	1987	The equilibrium dissociation constant, KS, for the interaction between MUGB and urokinase was 2.9 X 10(-6) M, and for the interaction with t-PA 3.13 X 10(-5) M. However, one main requirement for active-site titration, namely a stable acyl enzyme intermediate (ES"), was only fulfilled for MUGB urokinase but not for MUGB t-PA.	Potassium	39-41	plasminogen activator, tissue type	Homo sapiens	321-325
3102870-0	1987	Effect of opioid peptides and potassium on the release of vasoactive intestinal polypeptide and thyrotropin releasing hormone from perifused rat hypothalami.	Potassium	30-39	vasoactive intestinal peptide	Rattus norvegicus	58-91
3102870-0	1987	Effect of opioid peptides and potassium on the release of vasoactive intestinal polypeptide and thyrotropin releasing hormone from perifused rat hypothalami.	Potassium	30-39	thyrotropin releasing hormone	Rattus norvegicus	96-125
3032357-3	1987	The addition of potassium (40 mM) in excess, resulted in a highly significant elevation in the levels of CCK-LI in the cortical superfusate.	Potassium	16-25	cholecystokinin	Rattus norvegicus	105-108
3588515-3	1987	In the presence of scopolamine (0.3 microM), however, there was a large enhancement (87.0%) of potassium evoked release during soman inhibited (100%) AChE-activity.	Potassium	95-104	acetylcholinesterase	Rattus norvegicus	150-154
3034317-11	1987	Reduced aldosterone secondary to blockade of AII formation contributes to saluresis whilst encouraging positive potassium balance.	Potassium	112-121	angiotensinogen	Homo sapiens	45-48
2433697-0	1987	DNA synthesis and interferon release by human peripheral lymphocytes exposed to high potassium medium.	Potassium	85-94	interferon alpha 1	Homo sapiens	18-28
3300115-6	1987	Potassium also suppresses plasma renin activity which is not a uniform observation, however; patients who do not respond to K can have a raised plasma renin activity.	Potassium	0-9	renin	Homo sapiens	33-38
3300115-6	1987	Potassium also suppresses plasma renin activity which is not a uniform observation, however; patients who do not respond to K can have a raised plasma renin activity.	Potassium	0-9	renin	Homo sapiens	151-156
3324704-0	1987	Potassium supplementation lowers blood pressure in spontaneously hypertensive rats--relationships with urinary prostaglandins and renin.	Potassium	0-9	renin	Rattus norvegicus	130-135
3324704-3	1987	Plasma renin activity measured at the end of the study was significantly reduced in potassium supplemented animals compared to controls.	Potassium	84-93	renin	Rattus norvegicus	7-12
3035984-7	1987	The synthesis and secretion of VIP is also coupled to acetylcholine and elevated potassium stimulation by calcium influx.	Potassium	81-90	vasoactive intestinal peptide	Homo sapiens	31-34
2448106-0	1987	[Inactivation of the sodium pump leads to activation of potassium and inactivation of the chlorine channel in the chemoreceptor membrane of the giant neuron of the snail].	Potassium	56-65	snail family transcriptional repressor 1	Homo sapiens	164-169
2948755-1	1987	Previous studies have shown that atrial natriuretic peptide (ANP) inhibits the secretion of aldosterone by isolated adrenal glomerulosa cells stimulated by angiotensin II, adrenocorticotropic hormone and potassium in vitro.	Potassium	204-213	natriuretic peptide A	Rattus norvegicus	33-59
2948755-1	1987	Previous studies have shown that atrial natriuretic peptide (ANP) inhibits the secretion of aldosterone by isolated adrenal glomerulosa cells stimulated by angiotensin II, adrenocorticotropic hormone and potassium in vitro.	Potassium	204-213	natriuretic peptide A	Rattus norvegicus	61-64
3028812-5	1987	The increased plasma levels of insulin, but also of catecholamines and growth hormone, created a condition promoting potassium uptake in muscle cells.	Potassium	117-126	insulin	Homo sapiens	31-38
3559679-5	1987	High potassium (8.5 mM) induced a positive shift (+9 mV) in the reversal potential of GABAergic inhibitory postsynaptic potentials (IPSPs) in CA3c neurons without changing input resistance or resting potential.	Potassium	5-14	carbonic anhydrase 3	Homo sapiens	142-145
2442026-0	1987	Control of spontaneous epileptiform discharges by extracellular potassium: an "in vitro" study in the CA1 subfield of the hippocampal slice.	Potassium	64-73	carbonic anhydrase 1	Homo sapiens	102-105
2959578-4	1987	Calcium transport and ATPase share the following properties: (i) magnesium was required with a K0.5 of 0.7 mM and maximal pumping ATPase activity at 5 mM Mg-ATP; (ii) at saturating magnesium concentrations, calcium increased ATP splitting activity up to three times with an apparent K0.5 close to 0.3 microM calcium; (iii) potassium stimulated the high calcium affinity Mg2+-dependent ATPase and calcium transport.	Potassium	323-332	dynein axonemal heavy chain 8	Homo sapiens	22-28
3025550-0	1987	Ouabain and low extracellular potassium inhibit PTH secretion from bovine parathyroid cells by a mechanism that does not involve increases in the cytosolic calcium concentration.	Potassium	30-39	parathyroid hormone	Bos taurus	48-51
20501175-2	1987	ANP levels increased 5-fold in response to either forskolin or phorbol ester treatment, and 17-fold after depolarization by 40 mM potassium.	Potassium	130-139	natriuretic peptide A	Bos taurus	0-3
3502572-8	1987	Elevated potassium ion, which leads to the induction of c-fos in PC-12 cells via activation of a voltage-dependent Ca2+ channel, also induces all TIS genes, with the notable exception of TIS 10.	Potassium	9-18	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	56-61
3502572-8	1987	Elevated potassium ion, which leads to the induction of c-fos in PC-12 cells via activation of a voltage-dependent Ca2+ channel, also induces all TIS genes, with the notable exception of TIS 10.	Potassium	9-18	prostaglandin-endoperoxide synthase 2	Mus musculus	187-193
3598850-3	1987	Calcium, magnesium, potassium, and sodium initially stimulated NAT activity, and as the cation concentration increased inhibitory activity was observed.	Potassium	20-29	bromodomain containing 2	Homo sapiens	63-66
3025550-2	1987	Recent data have also shown that low extracellular potassium (K+) concentration or ouabain also inhibits PTH release to an extent comparable to that seen with high Ca++ and produce a marked rise in the intracellular sodium (Na+) content.	Potassium	51-60	parathyroid hormone	Bos taurus	105-108
2879627-5	1986	In contrast, selective beta2 adrenoceptor blockade (ICI 118551, 100 micrograms X kg-1) prevented the adrenaline induced lowering of serum potassium concentration but not of ventricular vulnerability.	Potassium	138-147	beta-2 adrenergic receptor	Canis lupus familiaris	23-41
3481117-1	1987	The effect of vasoactive intestinal peptide (VIP), secretin, and VIP-secretin (Ala4, Val5-secretin) on the net movements of sodium, potassium, fluid, and mucus was investigated in the rat colon perfused in vivo.	Potassium	132-141	vasoactive intestinal peptide	Rattus norvegicus	65-68
3023376-1	1986	Sodium and potassium ion-transport adenosine triphosphatase from dog kidney was incubated with 0.4-2 mM Ca2+ at 23 degrees C for more than 2 min in the absence of monovalent inorganic cations, cooled to 0 degrees C, and phosphorylated from 1 mM Pi with 2.4 mM MgCl2.	Potassium	11-20	carbonic anhydrase 2	Canis lupus familiaris	104-107
3539795-1	1986	We previously showed that adrenal renin is highest in the rat zona glomerulosa (ZG) and that low sodium or high potassium and nephrectomy increase adrenal ZG renin and aldosterone.	Potassium	112-121	renin	Rattus norvegicus	158-163
3096692-12	1986	Electrophysiological responses to TRH, dopamine, and elevated potassium were correlated with changes in the release of PRL.	Potassium	62-71	prolactin	Bos taurus	119-122
2948613-1	1986	The effect of specific D-2 dopamine (DA) receptor agonists and antagonists on potassium (55 mM)-evoked release of cholecystokinin-like immunoreactivity (CCK-LI) was studied in tissue slices of the rat posterior nucleus accumbens (NAc).	Potassium	78-87	cholecystokinin	Rattus norvegicus	153-156
2948563-6	1986	It is suggested that this low-affinity acceleration by ATP of the crucial step leading to dissociation of transported Ca2+ is the specific interaction responsible for the low-affinity acceleration of overall ATPase activity generally observed in the presence of potassium at neutral pH.	Potassium	262-271	dynein axonemal heavy chain 8	Homo sapiens	208-214
3801861-0	1986	Basal and potassium-evoked release of angiotensin II from the rat hypothalamus.	Potassium	10-19	angiotensinogen	Rattus norvegicus	38-52
3022647-0	1986	Potassium activation and its relationship to a highly reactive cysteine residue in fructose 1,6-bisphosphatase.	Potassium	0-9	fructose-bisphosphatase 1	Sus scrofa	83-110
2434679-4	1986	The results are illustrated by using the DiFrancesco-Noble (1985) model and its recent modifications: The potassium-dependence of the inward rectifier current, iK1 has a strong role to play in determining action potential duration and pacemaker activity in Purkinje tissue, but has a negligible role to play in sinoatrial node tissue.	Potassium	106-115	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	160-163
3817007-1	1986	Serum concentrations of calcium, magnesium, potassium and phosphate can be lowered experimentally by adrenaline, which also can stimulate the secretion of parathyroid hormone (PTH).	Potassium	44-53	parathyroid hormone	Homo sapiens	155-174
3021625-5	1986	Potassium also plays an important role, since prevention of hyperkalemia after nephrectomy by treatment with a cation exchange resin, sodium polystyrene sulfonate (Kayexalate), significantly reduced the adrenal renin response to nephrectomy.	Potassium	0-9	renin	Rattus norvegicus	211-216
3546914-0	1986	Augmented aldosterone and insulin responses to potassium infusion in dogs with renal failure.	Potassium	47-56	insulin	Canis lupus familiaris	26-33
3546914-1	1986	The present study examines acute potassium-induced insulin and aldosterone responses in renal failure, and the role of chronic dietary potassium intake in modifying these acute responses.	Potassium	33-42	insulin	Canis lupus familiaris	51-58
3021625-7	1986	Infusion of angiotensin II intraperitoneally prevented the rise in adrenal renin after nephrectomy (from 65.25 +/- 7.60 to 9.27 +/- 0.99 ng angiotensin I/mg protein/hr) despite an increase in plasma potassium and corticosterone.	Potassium	199-208	angiotensinogen	Rattus norvegicus	12-26
3021625-8	1986	In conclusion, three factors influence the response of adrenal renin to nephrectomy: 1) the pituitary through the release of ACTH, 2) a direct stimulation by high plasma potassium levels, 3) the lack of angiotensin II feedback inhibition.	Potassium	170-179	renin	Rattus norvegicus	63-68
3785588-0	1986	Vasoactive intestinal polypeptide (VIP) inhibits potassium-induced release of cholecystokinin (CCK) from rat caudato-putamen but not from cerebral cortex.	Potassium	49-58	vasoactive intestinal peptide	Rattus norvegicus	0-33
2879748-5	1986	In studies using a retrograde venous perfusion system of the bovine adrenal gland, marked releases of both VIP-LI and catecholamine (CA) were observed immediately after the infusion of potassium solution of a concentration of 56 mM in a Ca2+-dependent manner.	Potassium	185-194	vasoactive intestinal peptide	Bos taurus	107-110
2879748-6	1986	Ba2+ (2 mM) also stimulated the releases of VIP-LI and CA from the adrenal gland Carbachol (10(-4)M) stimulated CA secretion as much as high potassium and Ba2+, but the magnitude of VIP-LI release was lower.	Potassium	141-150	vasoactive intestinal peptide	Bos taurus	44-47
3532815-0	1986	Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells.	Potassium	58-67	basic leucine zipper nuclear factor 1	Homo sapiens	17-36
3532815-4	1986	The present study provides two additional lines of evidence that this protein is involved directly with the calcium-dependent changes in potassium permeability: its association with the membrane is calcium dependent; and calcium-dependent potassium efflux from resealed ghost is inhibited by the incorporation of antibodies raised against this cytoplasmic protein.	Potassium	137-146	basic leucine zipper nuclear factor 1	Homo sapiens	344-363
3532815-4	1986	The present study provides two additional lines of evidence that this protein is involved directly with the calcium-dependent changes in potassium permeability: its association with the membrane is calcium dependent; and calcium-dependent potassium efflux from resealed ghost is inhibited by the incorporation of antibodies raised against this cytoplasmic protein.	Potassium	239-248	basic leucine zipper nuclear factor 1	Homo sapiens	344-363
2876755-4	1986	However, exposure of 2-week-old cultures to depolarizing concentrations of potassium (K+; 40 mM) increased TOH activity approximately two-fold; total protein was unchanged, suggesting that the rise was due to increased TOH specific activity.	Potassium	75-84	tyrosine hydroxylase	Homo sapiens	107-110
2876755-4	1986	However, exposure of 2-week-old cultures to depolarizing concentrations of potassium (K+; 40 mM) increased TOH activity approximately two-fold; total protein was unchanged, suggesting that the rise was due to increased TOH specific activity.	Potassium	75-84	tyrosine hydroxylase	Homo sapiens	219-222
3785588-0	1986	Vasoactive intestinal polypeptide (VIP) inhibits potassium-induced release of cholecystokinin (CCK) from rat caudato-putamen but not from cerebral cortex.	Potassium	49-58	vasoactive intestinal peptide	Rattus norvegicus	35-38
3785588-0	1986	Vasoactive intestinal polypeptide (VIP) inhibits potassium-induced release of cholecystokinin (CCK) from rat caudato-putamen but not from cerebral cortex.	Potassium	49-58	cholecystokinin	Rattus norvegicus	78-93
3785588-0	1986	Vasoactive intestinal polypeptide (VIP) inhibits potassium-induced release of cholecystokinin (CCK) from rat caudato-putamen but not from cerebral cortex.	Potassium	49-58	cholecystokinin	Rattus norvegicus	95-98
3785588-1	1986	CCK release elicited by 40 mM potassium from slices of rat caudato-putamen (cp) was inhibited by VIP.	Potassium	30-39	cholecystokinin	Rattus norvegicus	0-3
3785588-1	1986	CCK release elicited by 40 mM potassium from slices of rat caudato-putamen (cp) was inhibited by VIP.	Potassium	30-39	vasoactive intestinal peptide	Rattus norvegicus	97-100
3022372-1	1986	Angiotensin I converting enzyme inhibition by captopril and enalapril may influence sodium and potassium homeostasis.	Potassium	95-104	angiotensin I converting enzyme	Homo sapiens	0-31
3758299-0	1986	High potassium intake increases the plasma concentration and urinary excretion of vasopressin in the rat.	Potassium	5-14	arginine vasopressin	Rattus norvegicus	82-93
3758299-1	1986	The effect of alterations of dietary potassium intake on the plasma concentration and the urinary excretion of vasopressin was studied in male rats.	Potassium	37-46	arginine vasopressin	Rattus norvegicus	111-122
3758299-2	1986	Ingestion of a high potassium diet resulted in increases in the plasma concentrations of potassium and vasopressin, systolic blood pressure, urine flow, and urinary vasopressin excretion.	Potassium	20-29	arginine vasopressin	Rattus norvegicus	103-114
3758299-2	1986	Ingestion of a high potassium diet resulted in increases in the plasma concentrations of potassium and vasopressin, systolic blood pressure, urine flow, and urinary vasopressin excretion.	Potassium	20-29	arginine vasopressin	Rattus norvegicus	165-176
3758299-3	1986	Ingestion of a low potassium diet had little effect on the plasma vasopressin concentration and systolic blood pressure but caused decreases in the plasma potassium concentration and urinary vasopressin excretion.	Potassium	19-28	arginine vasopressin	Rattus norvegicus	191-202
3758299-4	1986	The results indicate that physiological changes in the plasma potassium concentration or some other consequence of altered dietary potassium intake can affect vasopressin release and excretion.	Potassium	62-71	arginine vasopressin	Rattus norvegicus	159-170
3758299-4	1986	The results indicate that physiological changes in the plasma potassium concentration or some other consequence of altered dietary potassium intake can affect vasopressin release and excretion.	Potassium	131-140	arginine vasopressin	Rattus norvegicus	159-170
3752187-8	1986	In the presence of 10(-4) gm/ml of diltiazem, 10(-2) U/ml of oxytocin could not evoke any action potentials but did evoke small and long contractures, while in a high ionized potassium contracture experiment, oxytocin potentiated the tonic phase.	Potassium	175-184	oxytocin/neurophysin I prepropeptide	Homo sapiens	61-69
2875660-7	1986	In potassium-depleted rats the pressor response to AVP was 21-52% lower than that in controls, whereas cirrhotic rats also had a blunted response to AVP (14-41% lower than control).	Potassium	3-12	arginine vasopressin	Rattus norvegicus	51-54
2875660-0	1986	Pressor resistance to vasopressin in sodium depletion, potassium depletion, and cirrhosis.	Potassium	55-64	arginine vasopressin	Rattus norvegicus	22-33
2875660-1	1986	Resistance to the pressor effects of angiotensin II, but not norepinephrine, has been observed in sodium depletion, potassium depletion, and cirrhosis.	Potassium	116-125	angiotensinogen	Rattus norvegicus	37-51
3015710-4	1986	Elevated extracellular potassium, dibutyryl cyclic adenosine monophosphate, and the diterpene derivative forskolin each stimulated an increase in cholecystokinin release over a 60-min period compared to basal secretion.	Potassium	23-32	cholecystokinin	Canis lupus familiaris	146-161
3528445-2	1986	We present a systematic study of the interrelation between renal excretion of potassium and the renin-aldosterone axis in 23 children with CRF of different and unselected causes.	Potassium	78-87	renin	Homo sapiens	96-101
3018733-0	1986	Intracellular potassium depletion in IM-9 lymphocytes suppresses the slowly dissociating component of human growth hormone binding and the down-regulation of its receptors but does not affect insulin receptors.	Potassium	14-23	growth hormone 1	Homo sapiens	108-122
3756479-5	1986	In vital slices thinner than 500 micron cK+s-values exceeded the potassium-concentration of the bath (cK+B) only when pBO2 was markedly lowered.	Potassium	65-74	creatine kinase B-type	Cavia porcellus	102-106
3740056-4	1986	The results demonstrate that net potassium secretion was increased in subjects with renal failure (-5.2 +/- 0.9 microEq X min-1) compared with the control value of -2.0 +/- 0.4 microEq (P less than .05).	Potassium	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
2942746-0	1986	Effect of atrial natriuretic factor on the plasma aldosterone response to potassium infusion in rats--in vivo study.	Potassium	74-83	natriuretic peptide A	Rattus norvegicus	10-35
3768314-2	1986	The spectral binding constants (Ks) for HCB in control and PB-induced microsomes are 180 microM and 83 microM, respectively, and correlate inversely with the specific content of CYT P-450 (0.9 and 2.1 nmol/mg) in the two microsomal preparations.	Potassium	32-34	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	178-187
2871899-2	1986	Increasing the potassium ion concentration in the medium from 6 mM to 55 mM resulted in a significantly increased release of somatostatin.	Potassium	15-24	somatostatin	Rattus norvegicus	125-137
3742197-0	1986	Potassium-induced epileptiform activity in area CA3 varies markedly along the septotemporal axis of the rat hippocampus.	Potassium	0-9	carbonic anhydrase 3	Rattus norvegicus	48-51
3742197-2	1986	In this study, spontaneous epileptiform bursting was induced in area CA3 of rat hippocampal slices by bathing them in 7 mM potassium.	Potassium	123-132	carbonic anhydrase 3	Rattus norvegicus	69-72
2873027-2	1986	A high potassium concentration (56 mM) stimulated GRF release from the hypothalamus.	Potassium	7-16	growth hormone releasing hormone	Rattus norvegicus	50-53
3722149-9	1986	Zinc binding on the higher affinity sites regulates calcium binding to S100b by increasing the protein affinity for calcium and decreasing the antagonistic effect of potassium on calcium binding.	Potassium	166-175	S100 calcium binding protein B	Bos taurus	71-76
3090723-5	1986	Administration of GH decreased weight loss, caused retention of nitrogen, potassium, and phosphorus in amounts closely matching their proportions in skeletal muscle, and stimulated insulin production.	Potassium	74-83	growth hormone 1	Homo sapiens	18-20
3015785-6	1986	Anti-Thy-1.2 administration was similarly effective in C57B1/Ks and partially protective in C57BL/6 mice.	Potassium	61-63	thymus cell antigen 1, theta	Mus musculus	5-12
3084468-0	1986	Effect of interleukin-1 on intracellular concentration of sodium, calcium, and potassium in 70Z/3 cells.	Potassium	79-88	interleukin 1 complex	Mus musculus	10-23
3011941-4	1986	A high extracellular concentration of potassium (40 mmol/l) caused a three- to tenfold calcium-dependent increase in release of insulin and a parallel release of glucagon.	Potassium	38-47	glucagon	Rattus norvegicus	162-170
3521182-3	1986	Combined restriction of sodium, potassium and chloride elicited a decreased activity of the enzyme(s) involved in late steps in aldosterone biosynthesis, an elevation of plasma renin activity to excessively high levels and a substantial hypokalaemia.	Potassium	32-41	renin	Rattus norvegicus	177-182
3008159-1	1986	Previous studies have shown that atrial natriuretic peptide (ANP) inhibits the secretion of aldosterone by isolated adrenal glomerulosa cells stimulated by angiotensin II, ACTH and potassium in vitro and by angiotensin II in conscious unrestrained rats.	Potassium	181-190	natriuretic peptide A	Rattus norvegicus	33-59
3636040-3	1986	Adjusted kallikrein excretion was greater in youths than in adults and correlated with potassium excretion and sodium excretion in persons with normal blood pressure.	Potassium	87-96	kallikrein related peptidase 4	Homo sapiens	9-19
3522457-5	1986	There was a modest incidence of CsA toxicity as evidenced by the usual clinical monitoring and by evaluation of creatinine clearance, plasma potassium and evolution of renal parenchymal cells as studied in the course of sequential fine needle aspiration biopsies.	Potassium	141-150	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	32-35
3516300-4	1986	Glucose insulin potassium infusion (GIK) resulted in lower plasma nonesterified fatty acid, and blood 3-hydroxybutyrate and glycerol concentrations, with markedly higher serum insulin levels compared to patients managed with a "no insulin" regimen.	Potassium	16-25	insulin	Homo sapiens	8-15
3516300-4	1986	Glucose insulin potassium infusion (GIK) resulted in lower plasma nonesterified fatty acid, and blood 3-hydroxybutyrate and glycerol concentrations, with markedly higher serum insulin levels compared to patients managed with a "no insulin" regimen.	Potassium	16-25	insulin	Homo sapiens	176-183
2422345-6	1986	Veratridine, A23187 and elevated potassium ions decreased the levels of ATP and [3H]AdoMet.	Potassium	33-42	methionine adenosyltransferase 1A	Rattus norvegicus	84-90
3700233-6	1986	A glucose-insulin-potassium solution was used to treat septic shock in the dog that recovered.	Potassium	18-27	insulin	Canis lupus familiaris	10-17
2420805-0	1986	Increased voltage-gated potassium conductance during interleukin 2-stimulated proliferation of a mouse helper T lymphocyte clone.	Potassium	24-33	interleukin 2	Mus musculus	53-66
2420805-7	1986	When these cells are stimulated with human recombinant interleukin 2 (rIL2, 100 U/ml), they grow in size and initiate DNA synthesis at approximately 24 h. Potassium conductance is increased as early as 8 h after stimulation with rIL2 and rises to a level 3-4 times that of excipient controls by 24 h. The level remains elevated through 72 h, but as the cells begin to leave the cell cycle at 72-96 h, the conductance decreases quickly to a value only slightly higher than the initial one.	Potassium	155-164	interleukin 2	Homo sapiens	55-68
2420805-7	1986	When these cells are stimulated with human recombinant interleukin 2 (rIL2, 100 U/ml), they grow in size and initiate DNA synthesis at approximately 24 h. Potassium conductance is increased as early as 8 h after stimulation with rIL2 and rises to a level 3-4 times that of excipient controls by 24 h. The level remains elevated through 72 h, but as the cells begin to leave the cell cycle at 72-96 h, the conductance decreases quickly to a value only slightly higher than the initial one.	Potassium	155-164	interleukin 2	Rattus norvegicus	70-74
2420805-7	1986	When these cells are stimulated with human recombinant interleukin 2 (rIL2, 100 U/ml), they grow in size and initiate DNA synthesis at approximately 24 h. Potassium conductance is increased as early as 8 h after stimulation with rIL2 and rises to a level 3-4 times that of excipient controls by 24 h. The level remains elevated through 72 h, but as the cells begin to leave the cell cycle at 72-96 h, the conductance decreases quickly to a value only slightly higher than the initial one.	Potassium	155-164	interleukin 2	Rattus norvegicus	229-233
2420805-9	1986	The regulation of potassium conductance in L2 cells during rIL2-stimulated proliferation suggests that potassium channel function may play a role in support of the proliferative response.	Potassium	18-27	interleukin 2	Rattus norvegicus	59-63
2936740-0	1986	The vanadate-sensitive ATPase of Streptococcus faecalis pumps potassium in a reconstituted system.	Potassium	62-71	ATPase	Enterococcus faecalis	23-29
2936740-3	1986	Transport studies with 42K+ and with a K+-selective electrode showed that the ATP-ase catalyzes electrogenic potassium extrusion in proteoliposomes.	Potassium	109-118	ATPase	Enterococcus faecalis	78-85
2936740-6	1986	This ATPase thus appears to function as a potential regulated, ATP-driven pump that serves in electrogenic potassium accumulation by the bacterial cell.	Potassium	107-116	ATPase	Enterococcus faecalis	5-11
2940098-4	1986	ANF was found to be released from rat hypothalamus by a depolarizing concentration of potassium and by a calcium-dependent mechanism.	Potassium	86-95	natriuretic peptide A	Rattus norvegicus	0-3
3701404-0	1986	Histamine decreases calcium-mediated potassium current in guinea pig hippocampal CA1 pyramidal cells.	Potassium	37-46	carbonic anhydrase 1	Cavia porcellus	81-84
3701404-10	1986	The results support the conclusion that histamine selectively decreases the calcium-mediated potassium conductance in CA1 pyramidal cells of hippocampus.	Potassium	93-102	carbonic anhydrase 1	Cavia porcellus	118-121
3953823-3	1986	In one cell type (high basolateral conductance, HBC), these maneuvers cause large depolarizations in Vbl, suggesting that the basolateral cell membrane has significant partial conductances to both chloride and to potassium.	Potassium	213-222	keratin 88, pseudogene	Homo sapiens	48-51
3953823-6	1986	Increasing basolateral potassium to 98 mM causes both types to swell, with HBC cells swelling approximately two times faster than LBC cells.	Potassium	23-32	keratin 88, pseudogene	Homo sapiens	75-78
3953823-8	1986	In animals kept in a low-potassium environment, the number of HBC cells is approximately equal to the number of LBC cells.	Potassium	25-34	keratin 88, pseudogene	Homo sapiens	62-65
3514489-7	1986	It was concluded that the interplay of various factors, CAP, upright posture and impaired renal functions resulting in suppression of aldosterone and insulin played a role in the paradoxical glucose-induced serum potassium elevation.	Potassium	213-222	insulin	Homo sapiens	150-157
3006413-7	1986	The cells from heparin-treated rats had a less sensitive and lower response of aldosterone production to potassium; an increase by one order of magnitude in the threshold dose for potassium and a decrease in the maximum potassium-stimulated level, presumably because of the glomerulosa hyporesponsiveness to AII.	Potassium	105-114	angiotensinogen	Rattus norvegicus	308-311
3942729-3	1986	High extracellular potassium concentrations depolarize human fibroblasts and depress the activity of transport systems A, ASC (both serving for zwitterionic amino acids), X-AG (for anionic amino acids), and y+ (for cationic amino acids).	Potassium	19-28	PYD and CARD domain containing	Homo sapiens	122-125
2421238-3	1986	While the first negative peak is related to the propagating nerve action potential, the second negative deflection can be attributed to a potassium conductance since it was selectively blocked by tetraethylammonium (TEA) or 3,4-diaminopyridine (3,4-DAP).	Potassium	138-147	death-associated protein	Mus musculus	249-252
2419807-1	1986	Superfusion of slices of the dorsal half of rat spinal cord in vitro with 10 microM capsaicin or 60 mM potassium lead to the simultaneous release of substance P (SP)-, neurokinin A (NKA)- and calcitonin gene-related peptide (CGRP)-like immunoreactivities (LI).	Potassium	103-112	calcitonin-related polypeptide alpha	Rattus norvegicus	192-223
2419807-1	1986	Superfusion of slices of the dorsal half of rat spinal cord in vitro with 10 microM capsaicin or 60 mM potassium lead to the simultaneous release of substance P (SP)-, neurokinin A (NKA)- and calcitonin gene-related peptide (CGRP)-like immunoreactivities (LI).	Potassium	103-112	calcitonin-related polypeptide alpha	Rattus norvegicus	225-229
3535395-0	1986	The effect of sodium depletion and potassium supplementation on vasopressin, renin and catecholamines in hypertensive men.	Potassium	35-44	arginine vasopressin	Homo sapiens	64-75
3515823-7	1986	Fractional potassium excretion (CK/CIn) decreased by 34% (P less than 0.01) and 44% (P less than 0.01) at the two highest rates.	Potassium	11-20	pyridoxal phosphatase	Homo sapiens	35-38
3535395-0	1986	The effect of sodium depletion and potassium supplementation on vasopressin, renin and catecholamines in hypertensive men.	Potassium	35-44	renin	Homo sapiens	77-82
3535395-5	1986	With combined salt depletion and potassium supplementation, arterial plasma vasopressin decreased by 9.5 +/- 4.0 ng/l (p less than 0.05) compared to control.	Potassium	33-42	arginine vasopressin	Homo sapiens	76-87
3000733-9	1986	Cells from diabetic rats exhibited a less sensitive response of aldosterone production to potassium and a tendency to be low in the maximal potassium-stimulated aldosterone level, presumably attributable to the impairment of adrenal zona glomerulosa cells to AII.	Potassium	140-149	angiotensinogen	Rattus norvegicus	259-262
2870919-1	1986	UNLABELLED: These studies were designed to examine the effects of extracellular calcium ion (Ca++) concentration upon basal and dibutyryl (db) cAMP or potassium ion (K+)-stimulated release of growth hormone (GH) and to determine whether increased extracellular Ca++ can overcome somatostatin (SRIF)-inhibited release of stored rGH in parallel with its reported effect upon SRIF inhibition of stimulated insulin and glucagon release.	Potassium	151-160	gonadotropin releasing hormone receptor	Rattus norvegicus	192-206
3534045-9	1986	Multiple regression analysis revealed that urinary potassium excretion was influenced by age, race, sex, body weight, blood pressure, creatinine clearance, renin, and aldosterone.	Potassium	51-60	renin	Homo sapiens	156-161
3080471-2	1986	Our previous studies in cortical collecting ducts isolated from rat kidneys have shown that vasopressin increases both sodium absorption and potassium secretion, while bradykinin inhibits sodium absorption without affecting potassium transport.	Potassium	141-150	arginine vasopressin	Rattus norvegicus	92-103
2427869-7	1986	The beta 2-adrenoceptor-mediated increases in plasma cyclic AMP and decreases in plasma potassium were similar in the BHT and control groups.	Potassium	88-97	adrenoceptor beta 2	Homo sapiens	4-23
2948068-2	1986	After determination of basal renal function, ANF at different doses induced a dose dependent increase of glomerular filtration rate (GFR), diuresis (V), sodium (UNaV) and potassium (UKV) excretion.	Potassium	171-180	natriuretic peptide A	Rattus norvegicus	45-48
2867766-1	1985	High potassium (50 mM) depolarization induces a rapid (less than 15 sec) increase in the levels of the polyamines putrescine, spermidine and spermine and their rate-regulating synthetic enzyme ornithine decarboxylase in synaptosomes from rat cerebral cortex.	Potassium	5-14	ornithine decarboxylase 1	Rattus norvegicus	193-216
2946967-9	1986	In addition, a tremendous rise in fractional excretion rates of sodium and potassium after administration of ANF was observed.	Potassium	75-84	natriuretic peptide A	Rattus norvegicus	109-112
2433638-0	1986	Effects of Bay K 8644 and other dihydropyridines on basal and potassium-evoked output of MSH from mouse melanotrophs in vitro.	Potassium	62-71	msh homeobox 1	Mus musculus	89-92
3081913-5	1986	The bradykinin stimulated PGE2 and PGF2 alpha-production by control fibroblasts was directly proportional to extracellular potassium concentrations, whereas the PG-production of Bartter"s syndrome fibroblasts remained uninfluenced by extracellular potassium.	Potassium	123-132	kininogen 1	Homo sapiens	4-14
3019247-1	1985	The effects of potassium ions on pig kidney fructose-1,6-bisphosphatase activity have been studied.	Potassium	15-24	fructose-bisphosphatase 1	Sus scrofa	44-71
2998675-9	1985	Moreover, angiotensin II appears necessary for an adequate aldosterone response to potassium stimulation.	Potassium	83-92	angiotensinogen	Homo sapiens	10-24
2866707-1	1985	The renin-angiotensin-aldosterone system regulates blood pressure and volume homeostasis in addition to sodium and potassium metabolism, and may be linked to divalent cation metabolism as well as hypertensive disease.	Potassium	115-124	renin	Homo sapiens	4-9
3865201-4	1985	Removal of these groups by protein engineering shows that they contribute no binding energy with unreacted ATP but put all of their binding energy into stabilizing the [tyrosine-ATP] transition state [the mutant tyrosyl-tRNA synthetase (Thr-40----Ala-40; His-45----Gly-45) has the rate of formation of tyrosyl adenylate lowered by 3.2 X 10(5) but KS for ATP is lowered by only a factor of 5].	Potassium	347-349	tyrosyl-tRNA synthetase 1	Homo sapiens	212-235
4080113-0	1985	Elevated potassium stimulates enkephalin biosynthesis in bovine chromaffin cells.	Potassium	9-18	proenkephalin	Rattus norvegicus	30-40
4080113-1	1985	Exposure of bovine adrenal medullary cells in culture to a depolarizing concentration of potassium (50 mM), causes a rapid rise in both cellular and secreted Met-enkephalin peptide.	Potassium	89-98	proenkephalin	Rattus norvegicus	162-172
4080113-4	1985	Potassium stimulation of Met-enkephalin biosynthesis requires the presence of extracellular Ca2+ and is not observed in either low Ca2+ medium or in the presence of D600, a Ca2+ channel blocker.	Potassium	0-9	proenkephalin	Rattus norvegicus	29-39
2936967-4	1985	In the literature there is evidence for an increased sensitivity of the muscle membrane to insulin with an increased potassium-shift inside the cell in hypokalaemic periodic paralysis.	Potassium	117-126	insulin	Homo sapiens	91-98
4053513-0	1985	A vasopressin-mediated diminution of potassium excretion in water-loaded man.	Potassium	37-46	arginine vasopressin	Homo sapiens	2-13
2932646-1	1985	The renin-angiotensin-aldosterone axis exerts major control over sodium and potassium balance and arterial blood pressure.	Potassium	76-85	renin	Homo sapiens	4-9
2932646-2	1985	These three functions are continuously regulated by changes in angiotensin II and aldosterone levels in response to wide variations in dietary intake of sodium and potassium.	Potassium	164-173	angiotensinogen	Homo sapiens	63-77
3899615-0	1985	A role for the adrenal renin-angiotensin system in the regulation of potassium-stimulated aldosterone production.	Potassium	69-78	renin	Rattus norvegicus	23-28
3899615-3	1985	The causal relationship between potassium and adrenal renin is not known.	Potassium	32-41	renin	Rattus norvegicus	54-59
3899615-7	1985	In intact animals potassium loading markedly increased adrenal renin and plasma aldosterone, whereas PRA was suppressed.	Potassium	18-27	renin	Rattus norvegicus	63-68
3899615-11	1985	These results suggest that the adrenal renin-ANG system plays a significant role in the control of aldosterone production under potassium stimulation.	Potassium	128-137	renin	Rattus norvegicus	39-44
3908322-3	1985	On the other hand, the insulin-induced shift of potassium into the cell interior is transient and appears to be of little consequence for long-term blood pressure control.	Potassium	48-57	insulin	Homo sapiens	23-30
3003299-5	1985	In control studies there was a profound fall in serum glucose and plasma potassium after insulin, associated with increments in plasma renin activity, which correlated with those of aldosterone but not with those of ACTH and cortisol.	Potassium	73-82	insulin	Homo sapiens	89-96
3003299-7	1985	During converting enzyme inhibition the insulin-induced decrements in glucose and potassium, as well as the increments in ACTH, cortisol and aldosterone, were similar to those observed in control studies, whereas the increments in plasma renin activity were much greater.	Potassium	82-91	insulin	Homo sapiens	40-47
3854057-7	1985	In addition, these finding suggest that some kallikrein-modulating factor(s) may counteract the increased urinary kallikrein excretion with the augmented renin-angiotensin-aldosterone system during salt loading with potassium supplementation.	Potassium	216-225	renin	Homo sapiens	154-159
3007820-0	1985	[Effects of angiotensin I converting enzyme inhibitor on renal function and serum potassium in renal and renovascular hypertension].	Potassium	82-91	angiotensin I converting enzyme	Homo sapiens	12-43
2416580-2	1985	Bay K 8644 produced a dose-related inhibition of renin release in the presence of 15 mM potassium.	Potassium	88-97	renin	Rattus norvegicus	49-54
2419176-9	1985	The cells from dextran sulfate-treated rats had a less sensitive and lower response of aldosterone production to potassium; an increase by one order of magnitude in the threshold dose for potassium and a decrease in the maximum potassium-stimulated level, presumably because of the glomerulosa hyporesponsiveness to AII.	Potassium	113-122	angiotensinogen	Rattus norvegicus	316-319
3930219-4	1985	Potassium-induced depolarization (60 mM KCl) resulted in a 170% increase in TRH release compared to that by the Krebs-Ringer bicarbonate control (P less than 0.05).	Potassium	0-9	thyrotropin releasing hormone	Rattus norvegicus	76-79
3930219-10	1985	2) The secretion of TRH is stimulated by potassium-induced depolarization in a calcium-dependent manner, suggesting a classic neurosecretory process of release.	Potassium	41-50	thyrotropin releasing hormone	Rattus norvegicus	20-23
2997291-9	1985	Stimulation of potassium efflux by A23187 was additive to the VIP-stimulated potassium efflux.	Potassium	15-24	vasoactive intestinal peptide	Homo sapiens	62-65
2997291-9	1985	Stimulation of potassium efflux by A23187 was additive to the VIP-stimulated potassium efflux.	Potassium	77-86	vasoactive intestinal peptide	Homo sapiens	62-65
4053513-1	1985	Intravenous vasopressin (1-3 mu-units min-1 kg-1) had an antidiuretic effect on water-loaded man and also diminished potassium excretion.	Potassium	117-126	arginine vasopressin	Homo sapiens	12-23
4053513-3	1985	After terminating the infusion of vasopressin, the fall in potassium output persisted longer than the antidiuresis, which makes it unlikely that the antikaliuretic effect of vasopressin is secondary to its effect on urine flow.	Potassium	59-68	arginine vasopressin	Homo sapiens	34-45
4053513-4	1985	The unchanged antikaliuretic effect of vasopressin after aspirin treatment, together with its persistence after terminating the infusion, suggest the possible existence of vasopressin-mediated potassium absorption in the distal nephron in certain circumstances.	Potassium	193-202	arginine vasopressin	Homo sapiens	172-183
2931997-9	1985	Furthermore, our data suggest that ANF increases potassium excretion only if it increases GFR.	Potassium	49-58	natriuretic peptide A	Rattus norvegicus	35-38
4045551-2	1985	In this study, we have examined the action of CCK-peptides on the basal and potassium-evoked release of [3H]DA within this structure.	Potassium	76-85	cholecystokinin	Rattus norvegicus	46-49
4045551-8	1985	In contrast to its effects on the basal release of [3H]DA, sulfated CCK-octapeptide was found to attenuate the potassium-evoked release of [3H]DA from the NAc in a concentration-dependent fashion from 2 X 10(-9) to 2 X 10(-6) M. The unsulfated form of the octapeptide had no effect on evoked release.	Potassium	111-120	cholecystokinin	Rattus norvegicus	68-71
2999648-0	1985	Effects of noradrenaline on some potassium currents in CA1 neurones in rat hippocampal slices.	Potassium	33-42	carbonic anhydrase 1	Rattus norvegicus	55-58
2993343-2	1985	alpha hANP (3.2 X 10(-7) M) significantly inhibited both basal and potassium (16 mM)-stimulated aldosterone secretion, whereas it had little or no effect on aldosterone secretion submaximally or maximally stimulated by ACTH (3.4 X 10(-10)-3.4 X 10(-9) M) or angiotensin II (10(-8)-10(-9) M).	Potassium	67-76	natriuretic peptide A	Homo sapiens	6-10
4057105-8	1985	Exposure of n.i.l.s to depolarizing concentrations of potassium (high K+, 60 mM, 30 min) increased the vasopressin release more than 33-fold.	Potassium	54-63	arginine vasopressin	Rattus norvegicus	103-114
4030040-1	1985	The effects of moderate restriction of dietary sodium and potassium supplementation on plasma levels of renin, angiotensin II, aldosterone, and cortisol and on arterial pressure were studied in 12 patients with mild essential hypertension.	Potassium	58-67	renin	Homo sapiens	104-109
2864682-8	1985	ACE inhibition reduces symptoms, enhances exercise capacity, and favorably affects sodium, water, and potassium homeostasis in patients with heart failure.	Potassium	102-111	angiotensin I converting enzyme	Homo sapiens	0-3
4030790-10	1985	N-Ethylmaleimide, ethylenediaminetetraacetic acid, AMP, pyrophosphate, spermine, spermidine, and high concentrations of potassium inhibited both P1 and eIF-2 alpha phosphorylation by the purified kinase, whereas ethylene glycol bis(beta-aminoethyl ether)-N,N,N",N"-tetraacetic acid and phenanthroline did not significantly affect the phosphorylation of either protein P1 or eIF-2 alpha.	Potassium	120-129	eukaryotic translation initiation factor 2A	Mus musculus	152-163
4030790-10	1985	N-Ethylmaleimide, ethylenediaminetetraacetic acid, AMP, pyrophosphate, spermine, spermidine, and high concentrations of potassium inhibited both P1 and eIF-2 alpha phosphorylation by the purified kinase, whereas ethylene glycol bis(beta-aminoethyl ether)-N,N,N",N"-tetraacetic acid and phenanthroline did not significantly affect the phosphorylation of either protein P1 or eIF-2 alpha.	Potassium	120-129	eukaryotic translation initiation factor 2A	Mus musculus	374-385
3902475-5	1985	In those patients with active plasma renin concentrations above the normal range (greater than 50 microU ml-1) total body potassium was even more markedly deplete (85 + 13% of predicted normal).	Potassium	122-131	renin	Homo sapiens	37-42
3929618-3	1985	During the AVP infusion, there were significant increases in amniotic fluid osmolality (278.8 +/- 4.9 to 302.1 +/- 4.5 mosm) and in sodium (122.7 +/- 3.3 to 135.3 +/- 3.6 meq/l) and potassium (9.7 +/- 2.6 to 13.8 +/- 1.3 meq/l) concentrations.	Potassium	182-191	vasopressin-neurophysin 2-copeptin	Ovis aries	11-14
3929618-4	1985	Saline infusion after the AVP infusion resulted in return of AF osmolality, sodium, and potassium toward normal levels.	Potassium	88-97	vasopressin-neurophysin 2-copeptin	Ovis aries	26-29
16664379-8	1985	Potassium inhibited maize PDC and was competitive with pyruvate (root PDC K(i) = 16 millimolar and kernel PDC K(i) = 10 millimolar).	Potassium	0-9	pyruvate decarboxylase 2	Zea mays	26-29
16664379-8	1985	Potassium inhibited maize PDC and was competitive with pyruvate (root PDC K(i) = 16 millimolar and kernel PDC K(i) = 10 millimolar).	Potassium	0-9	pyruvate decarboxylase 2	Zea mays	70-73
16664379-8	1985	Potassium inhibited maize PDC and was competitive with pyruvate (root PDC K(i) = 16 millimolar and kernel PDC K(i) = 10 millimolar).	Potassium	0-9	pyruvate decarboxylase 2	Zea mays	70-73
3926198-3	1985	The mean (SD) serum potassium concentration on presentation to hospital with ketoacidosis was significantly higher in patients treated with a pump (5.7 (1.1) mmol(mEq)/l) than those treated with conventional injections of insulin (4.9(0.9) mmol/l; p less than 0.01).	Potassium	20-29	insulin	Homo sapiens	222-229
3902475-7	1985	Total body potassium increased significantly on captopril, and the rise was greatest in those with the highest plasma renin concentrations during the placebo phase of the study.	Potassium	11-20	renin	Homo sapiens	118-123
3902485-2	1985	A potassium concentration above 15 mMol/l shortly stimulates the insulin and glucagon secretion.	Potassium	2-11	insulin	Canis lupus familiaris	65-72
3902485-3	1985	Potassium ions (greater than or equal to 15 mMol/l) completely inhibit the early phase of glucose-induced insulin release.	Potassium	0-9	insulin	Canis lupus familiaris	106-113
4055233-0	1985	Equilibrium and kinetic study of sodium- and potassium-induced conformational changes of apo-alpha-lactalbumin.	Potassium	45-54	lactalbumin alpha	Homo sapiens	93-110
2997657-0	1985	Calcium-dependent potassium-stimulated release of neurokinin A and neurokinin B from rat brain regions in vitro.	Potassium	18-27	tachykinin precursor 3	Rattus norvegicus	67-79
3878504-7	1985	High concentrations of CGRP also caused a concentration-dependent relaxation on the precontracted preparations produced by high potassium (60 mM K+) solution.	Potassium	128-137	calcitonin-related polypeptide alpha	Rattus norvegicus	23-27
2412077-1	1985	The stimulation of insulin secretion from the beta cells of the islets of Langerhans appears to be mediated by a decrease in the cell-membrane potassium-ion permeability.	Potassium	143-152	insulin	Homo sapiens	19-26
2863970-1	1985	Experimental evidence is presented that activation of beta 2 adrenoreceptors causes a dose-dependent decrease in plasma potassium, probably by shifting potassium into the cell.	Potassium	120-129	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	54-60
2863970-1	1985	Experimental evidence is presented that activation of beta 2 adrenoreceptors causes a dose-dependent decrease in plasma potassium, probably by shifting potassium into the cell.	Potassium	152-161	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	54-60
2411327-4	1985	The exposure of rat vas deferens to phentolamine (10 microM) increased the release of tritium induced by potassium (59 mM) and electrical field stimulation.	Potassium	105-114	arginine vasopressin	Rattus norvegicus	20-23
2861079-4	1985	In the presence of a normal calcium level (1.3 mM) an increase in potassium from 4.4-13.8 mM caused enhanced SS output (from 46 +/- 8 pg/ml to 74 +/- 10 pg/ml; 2 P less than 0.05).	Potassium	66-75	somatostatin	Canis lupus familiaris	109-111
2864131-5	1985	Metoprolol and high concentrations of H35/25 further contracted large coronary arteries partially contracted by 25 mM potassium.	Potassium	118-127	H3.5 histone	Homo sapiens	38-44
2992681-3	1985	The post-hypoxic hyperexcitability of CA1 neurons may be the result of their inability to fully recover intracellular potassium lost during oxygen deprivation.	Potassium	118-127	carbonic anhydrase 1	Rattus norvegicus	38-41
4019771-6	1985	Arginine vasopressin (10(-10) M in the bath) caused a sustained fourfold increase in net sodium absorption and a sustained threefold increase in net potassium secretion.	Potassium	149-158	arginine vasopressin	Rattus norvegicus	9-20
3996489-4	1985	On the other hand, a potassium-specific ionophore, valinomycin, did not cause potentiation, but rather suppressed epo-dependent colony formation.	Potassium	21-30	erythropoietin	Mus musculus	114-117
4033070-4	1985	Significant early (2 hr) mitochondrial increases in potassium and phosphorus were found following administration of CCl4.	Potassium	52-61	C-C motif chemokine ligand 4	Rattus norvegicus	116-120
4019771-10	1985	Arginine vasopressin causes a reversible increase in net potassium secretion and net sodium absorption.	Potassium	57-66	arginine vasopressin	Rattus norvegicus	9-20
2415873-8	1985	Moreover, potassium- or veratridine-induced membrane depolarization increased tyrosine hydroxylase but decreased substance P, somatostatin and norepinephrine levels.	Potassium	10-19	somatostatin	Rattus norvegicus	126-138
2989039-1	1985	GnRH, high potassium concentrations, and cAMP derivatives have been previously shown to increase GnRH receptor levels (GnRH-R) in cultured rat pituitary cells.	Potassium	11-20	gonadotropin releasing hormone receptor	Rattus norvegicus	119-125
2485263-0	1985	Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension.	Potassium	54-63	angiotensin I converting enzyme	Homo sapiens	10-39
2485263-6	1985	The handling of the potassium load was altered by ACE inhibition.	Potassium	20-29	angiotensin I converting enzyme	Homo sapiens	50-53
3839572-3	1985	Addition of potassium (45 mM) resulted in a 3-fold increase in the rate of NPY release in a calcium dependent fashion.	Potassium	12-21	neuropeptide Y	Bos taurus	75-78
2582270-4	1985	Substance P depolarizes these cultured neurones by reducing an inwardly rectifying potassium conductances; this conductance has been found in several neuronal types and has similar properties to those of certain other cells.	Potassium	83-92	tachykinin precursor 1	Homo sapiens	0-11
3926504-0	1985	Insulin in vivo increases the in vitro fall of plasma potassium concentration in human venous blood.	Potassium	54-63	insulin	Homo sapiens	0-7
3926504-2	1985	Blood obtained 15 min after the intravenous administration of insulin (0.67 nmol kg-1 body weight) and incubated under the same conditions showed a significantly greater fall in the mean plasma potassium concentration of 0.33 mmol l-1 (SEM 0.09, P less than 0.05, n = 6).	Potassium	194-203	insulin	Homo sapiens	62-69
3926504-4	1985	The transfer of plasma from pre-insulin blood samples to blood cells obtained 15 min after insulin administration and vice versa indicated that the fall in plasma potassium concentration was a property of the 15 min post-insulin blood cells, presumably erythrocytes, rather than the plasma.	Potassium	163-172	insulin	Homo sapiens	32-39
3926504-4	1985	The transfer of plasma from pre-insulin blood samples to blood cells obtained 15 min after insulin administration and vice versa indicated that the fall in plasma potassium concentration was a property of the 15 min post-insulin blood cells, presumably erythrocytes, rather than the plasma.	Potassium	163-172	insulin	Homo sapiens	91-98
3926504-4	1985	The transfer of plasma from pre-insulin blood samples to blood cells obtained 15 min after insulin administration and vice versa indicated that the fall in plasma potassium concentration was a property of the 15 min post-insulin blood cells, presumably erythrocytes, rather than the plasma.	Potassium	163-172	insulin	Homo sapiens	91-98
4019886-5	1985	Interactions of environment and breed with dietary potassium treatment suggest differences in feed intake and milk yield responses to increasing dietary potassium content.	Potassium	51-60	Weaning weight-maternal milk	Bos taurus	110-114
4019886-5	1985	Interactions of environment and breed with dietary potassium treatment suggest differences in feed intake and milk yield responses to increasing dietary potassium content.	Potassium	153-162	Weaning weight-maternal milk	Bos taurus	110-114
4019886-6	1985	Total daily feed intake and milk yield of cows with no shade responded in curvilinear fashion to increasing dietary potassium, whereas responses in shade were small.	Potassium	116-125	Weaning weight-maternal milk	Bos taurus	28-32
4019886-8	1985	Milk yield of Holsteins increased with increasing dietary potassium, but yield of Jerseys did not.	Potassium	58-67	Weaning weight-maternal milk	Bos taurus	0-4
2860336-7	1985	Inhalation of beta 2-agonists may be dangerous, especially in patients under stress--eg, during an acute asthmatic attack, when the plasma potassium concentration would already be subnormal as the result of raised circulating adrenaline levels.	Potassium	139-148	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	14-20
3924125-0	1985	[Effect of calmodulin blockers on membrane potential, potassium permeability and lymphocyte mitogenesis].	Potassium	54-63	calmodulin 1	Homo sapiens	11-21
2988116-3	1985	Among the regulatory processes of internal potassium balance, the importance of adrenergic stimuli/drugs, of acid-base balance, and of magnesium and insulin is stressed.	Potassium	43-52	insulin	Homo sapiens	149-156
2992649-0	1985	Forskolin: its effects on potassium-evoked release of vasopressin from the rat neurohypophysis.	Potassium	26-35	arginine vasopressin	Rattus norvegicus	54-65
2992649-1	1985	The effect of forskolin, added either before or 5 min after the onset of potassium-evoked release of vasopressin from isolated neurointermediate lobes of the rat has been investigated.	Potassium	73-82	arginine vasopressin	Rattus norvegicus	101-112
2992649-2	1985	A low concentration of forskolin (1 microM), added before stimulation, enhanced the potassium-evoked release of vasopressin throughout two successive 5 min periods of stimulation.	Potassium	84-93	arginine vasopressin	Rattus norvegicus	112-123
2992854-1	1985	ACTH 1 mg/day for 5 days raises systolic blood pressure (SBP) in normotensive and hypertensive subjects on a fixed electrolyte intake of 100 mmol/day sodium (Na) and potassium (K) (Whitworth et al.	Potassium	166-175	proopiomelanocortin	Homo sapiens	0-4
4008616-3	1985	This led us to study the effect of the intravenous administration of salbutamol, a specific beta-2-adrenergic agonist, on serum potassium in 9 healthy subjects and in 23 patients with allergic asthma and/or rhinitis.	Potassium	128-137	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	92-98
3886368-9	1985	In vitro, the potassium-induced release of GnRH from perifused medial hypothalami was reduced by 60% in 4-APP-treated male rats while hypothalamic GnRH content remained unchanged.	Potassium	14-23	gonadotropin releasing hormone 1	Rattus norvegicus	43-47
3886368-9	1985	In vitro, the potassium-induced release of GnRH from perifused medial hypothalami was reduced by 60% in 4-APP-treated male rats while hypothalamic GnRH content remained unchanged.	Potassium	14-23	gonadotropin releasing hormone 1	Rattus norvegicus	147-151
3886748-6	1985	In all patients who had elevated serum potassium concentrations caused by massive digitalis toxicity, treatment with the Fab fragments reversed the hyperkalemia.	Potassium	39-48	FA complementation group B	Homo sapiens	121-124
2410804-4	1985	Potassium-induced release of TRH and 5-HT ex vivo was measured from tissue slices of the nucleus accumbens, septal nuclei and lumbar spinal cord after treatment with amitriptyline and mianserin.	Potassium	0-9	thyrotropin releasing hormone	Rattus norvegicus	29-32
4035682-6	1985	The sulfone showed type I interaction with the cytochrome P-450 (Ks, 0.17 mM).	Potassium	65-67	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	47-63
2983540-1	1985	Studies in rats have shown that fecal potassium excretion and colonic mucosa Na-K-ATPase activity are elevated during dietary potassium loading and in chronic renal insufficiency.	Potassium	126-135	dynein axonemal heavy chain 8	Homo sapiens	82-88
3157329-7	1985	These results suggest that the pattern of renal electrolyte excretion elicited in response to the acute infusion of atrial natriuretic factor is dependent, at least partially, on the preexisting status of the renal tubules to facilitate sodium reabsorption and potassium excretion.	Potassium	261-270	natriuretic peptide A	Canis lupus familiaris	116-141
2857721-8	1985	Thus, recovery of renal gamma-glutamyltranspeptidase specific activity after acivicin treatment can be used in vivo to determine absolute values of ks and kd for this enzyme.	Potassium	148-150	gamma-glutamyltransferase 1	Rattus norvegicus	24-52
2857853-2	1985	Fat mass is calculated by subtracting daily fluid (calculated from sodium and potassium balances) and protein mass changes from daily weight changes.	Potassium	78-87	FAT atypical cadherin 1	Homo sapiens	0-3
2983540-6	1985	Like others, however, we found a two-fold increase in Na-K-ATPase activity in potassium loaded rats.	Potassium	78-87	dynein axonemal heavy chain 8	Homo sapiens	59-65
2857179-8	1985	Incorporation of fibronectin into fibrin gels during formation leads to an increase in turbidity and a small decrease in Ks (permeability coefficient).	Potassium	121-123	fibronectin 1	Homo sapiens	17-28
2985222-3	1985	In the presence of CEI, ANF enhanced the excretion of sodium and potassium but not of calcium and urine.	Potassium	65-74	natriuretic peptide A	Rattus norvegicus	24-27
2985222-2	1985	In the absence of CEI, ANF produced rapid and significant increases in sodium, potassium, calcium, and urine excretions while blood pressure declined transiently.	Potassium	79-88	natriuretic peptide A	Rattus norvegicus	23-26
3898040-4	1985	Furthermore, based on immunocytochemistry and cresyl violet staining in combination with immunocytochemistry, the isolated cell fraction appeared to be free from other types of cells and also exhibited assayable LRF release when challenged with potassium.	Potassium	245-254	zinc finger and BTB domain containing 7a	Rattus norvegicus	212-215
3841647-6	1985	These showed that MLCK binds to phosphorylated and dephosphorylated myosin with approximately equal affinity (Ks = 30 X 10(-9) M).	Potassium	110-112	myosin light chain kinase	Homo sapiens	18-22
2985484-4	1985	Whereas serum potassium levels fell in association with ACTH, serum sodium was unchanged.	Potassium	14-23	proopiomelanocortin	Canis lupus familiaris	56-60
2981284-2	1985	Elevated potassium (56 mM) and carbamylcholine (carbachol, 10(-4) M) cause rapid increases in cyclic AMP levels in the cultures that show a time course similar to that of evoked dopamine release.	Potassium	9-18	transmembrane serine protease 5	Rattus norvegicus	101-104
2981380-2	1985	The results proved conclusively that ANF acted directly on the kidney since urine volume and fractional excretion of sodium, potassium, chloride and calcium were elevated in a dose-related manner in the ANF-treated kidney, but were not significantly affected in the contralateral saline-infused organ.	Potassium	125-134	natriuretic peptide A	Rattus norvegicus	37-40
2983324-1	1985	A mouse pituitary tumor cell line (AtT-20) releases corticotropin (ACTH) in response to a number of secretagogues, including corticotropin-releasing factor (CRF), beta-adrenergic agents, N6,O2"-dibutyryladenosine 3",5"-cyclic monophosphate (Bt2 cAMP), and potassium.	Potassium	256-265	pro-opiomelanocortin-alpha	Mus musculus	67-71
2981380-2	1985	The results proved conclusively that ANF acted directly on the kidney since urine volume and fractional excretion of sodium, potassium, chloride and calcium were elevated in a dose-related manner in the ANF-treated kidney, but were not significantly affected in the contralateral saline-infused organ.	Potassium	125-134	natriuretic peptide A	Rattus norvegicus	203-206
3970646-4	1985	The Dead Sea has a uniquely high concentration of calcium, magnesium, sodium, potassium, and chloride.	Potassium	78-87	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	9-12
3974261-0	1985	Calmodulin: calcium, potassium, and magnesium ion multiple equilibria and kinetics for interconversion, including the effect of repeated stimulation.	Potassium	21-30	calmodulin 1	Homo sapiens	0-10
2982240-3	1985	However, if the captopril/dexamethasone administered rats were given maintenance doses of angiotensin II and ACTH, potassium loading was found to exert a strong trophic action.	Potassium	115-124	angiotensinogen	Rattus norvegicus	90-104
4013686-1	1985	The concentration of prolactin in amniotic fluid from 91 pregnant women (Group I: 51 specimens obtained at 15th-20th week of gestation; Group II: 40 specimens at term) has been correlated with the amniotic fluid concentrations of calcium, of the ions sodium, chloride, and potassium, and with the clinical data.	Potassium	273-282	prolactin	Homo sapiens	21-30
3902499-0	1985	A pharmacological characterization of chloride- and potassium-dependent inhibitions in the CA3 region of the rat hippocampus in vitro.	Potassium	52-61	carbonic anhydrase 3	Rattus norvegicus	91-94
3924537-0	1985	[Effect of calmodulin blockers on the membrane potential and potassium permeability of thymocytes].	Potassium	61-70	calmodulin 1	Homo sapiens	11-21
3158341-1	1985	The mechanism of sarcoplasmic reticulum (SR) ATPase Mg2+-dependent phosphorylation from Pi was investigated in the presence of 15% v/v dimethyl sulfoxide at pH 6, 20 degrees C, and in the absence of potassium.	Potassium	199-208	dynein axonemal heavy chain 8	Homo sapiens	45-51
3158341-8	1985	In the absence of solvent, the interaction of magnesium with the calcium-deprived ATPase was also characterized from the point of view of phosphoenzyme formation from ATP or Pi at pH 7 in the absence of potassium: we found that calcium-independent phosphorylation was slower when phosphate was added to SR vesicles preincubated with magnesium that when magnesium was added to vesicles preincubated with phosphate, suggesting that preincubation with magnesium had depleted the phosphate-reactive conformation of the ATPase.	Potassium	203-212	dynein axonemal heavy chain 8	Homo sapiens	82-88
3896513-9	1985	The endogenous NPY-like material of the frog retina can be released by potassium depolarisation in a calcium-dependent way.	Potassium	71-80	neuropeptide Y	Oryctolagus cuniculus	15-18
3884328-6	1985	Aldosterone secretion is regulated by a multiplicative interaction between angiotensin II and potassium concentration.	Potassium	94-103	angiotensinogen	Homo sapiens	75-89
3917290-6	1985	However, depolarization by 55 mM potassium induced measurable PLP release.	Potassium	33-42	proteolipid protein 1	Rattus norvegicus	62-65
2580175-5	1985	Reduced aldosterone release consequent on the block of angiotensin II formation also contributes to the natriuresis and results in positive potassium balance.	Potassium	140-149	angiotensinogen	Homo sapiens	55-69
2579215-11	1985	After blockade of INaP and sodium spikes, Ca2+ spikes could be evoked only if potassium currents were first depressed.	Potassium	78-87	NFKB inhibitor zeta	Homo sapiens	18-22
2579215-6	1985	After depressing potassium currents with blocking agents, INaP could be observed during depolarizations to about 40 mV positive to RP where it is normally hidden by the larger outward currents.	Potassium	17-26	NFKB inhibitor zeta	Homo sapiens	58-62
2983148-3	1985	Renin and aldosterone measurements showed that changes in the sodium and potassium excretion were produced by a lower activity of the renin-angiotensin-aldosterone system in the first 1.5 hour of hypokinesia.	Potassium	73-82	renin	Homo sapiens	0-5
2983148-3	1985	Renin and aldosterone measurements showed that changes in the sodium and potassium excretion were produced by a lower activity of the renin-angiotensin-aldosterone system in the first 1.5 hour of hypokinesia.	Potassium	73-82	renin	Homo sapiens	134-139
20493019-2	1985	Chloroquine and quinacrine, which block the action of phospholipase A(2), inhibited either the phospholipase A(2)-stimulated or the high potassium-stimulated release of [(3)H]norepinephrine from synaptosomes.	Potassium	137-146	phospholipase A2 group IB	Rattus norvegicus	54-72
2984589-0	1985	Forskolin inhibits potassium-evoked release of vasopressin from rat neurohypophyses.	Potassium	19-28	arginine vasopressin	Rattus norvegicus	47-58
6094152-2	1984	In chronic experimental diabetic rats where PRA, plasma aldosterone concentration, and urinary excretion of prostaglandin E2 were significantly decreased, a significant attenuated response of aldosterone secretion was demonstrated after infusion of angiotensin II, ACTH, or potassium.	Potassium	274-283	angiotensinogen	Rattus norvegicus	249-263
2995937-2	1985	To demonstrate the possibility that POMC peptides may be neuroregulators which can be secreted in response to specific stimuli, we studied the secretion of immunoreactive (IR-) adrenocorticotropin (ACTH) and IR-beta-endorphin from dissociated hypothalamic cells during potassium-induced depolarization.	Potassium	269-278	proopiomelanocortin	Homo sapiens	36-40
2995937-4	1985	CONCLUSION: Stimulated secretion of POMC peptides from hypothalamic cells by potassium and calcium follows classical neurosecretory mechanisms and suggests these neuropeptides could be neuroregulators in brain.	Potassium	77-86	proopiomelanocortin	Homo sapiens	36-40
3974883-7	1985	The delivery of intact antibodies raised against calmodulin directly into the cytoplasm of cultured chromaffin cells by erythrocyte ghost-mediated microinjection, inhibited catecholamine output in response to stimulation by either acetylcholine (10(-4) M) or a depolarizing concentration of potassium (56 mM).	Potassium	291-300	calmodulin 1	Rattus norvegicus	49-59
4088825-4	1985	Ammonium is a substrate for the sodium and potassium site in the rectal gland but only for the potassium site in the TALH.	Potassium	95-104	transaldolase 1	Homo sapiens	117-121
6392920-6	1984	Stimulation with potassium (80 mM) induced an equally strong release of PGE2 and LHRH from the MEs of both fed and starved rats.	Potassium	17-26	gonadotropin releasing hormone 1	Rattus norvegicus	81-85
6441716-0	1984	Effects of potassium supplementation on insulin binding and insulin action in human obesity: protein-modified fast and refeeding.	Potassium	11-20	insulin	Homo sapiens	40-47
6441716-0	1984	Effects of potassium supplementation on insulin binding and insulin action in human obesity: protein-modified fast and refeeding.	Potassium	11-20	insulin	Homo sapiens	60-67
6441716-3	1984	The maintenance of normal potassium balance and normal serum potassium levels with oral potassium-chloride supplementation was associated with higher peripheral levels of insulin (P less than 0.01) and improvement of peripheral glucose utilization (P less than 0.01) whereas the binding of insulin to monocytes was unchanged.	Potassium	26-35	insulin	Homo sapiens	171-178
6441716-3	1984	The maintenance of normal potassium balance and normal serum potassium levels with oral potassium-chloride supplementation was associated with higher peripheral levels of insulin (P less than 0.01) and improvement of peripheral glucose utilization (P less than 0.01) whereas the binding of insulin to monocytes was unchanged.	Potassium	61-70	insulin	Homo sapiens	171-178
6441716-4	1984	The data suggest that potassium depletion during protein-modified fast causes a decrease of the peripheral levels of insulin and a resistance to insulin action at the postreceptors sites which is reversed by potassium supply.	Potassium	22-31	insulin	Homo sapiens	117-124
6441716-4	1984	The data suggest that potassium depletion during protein-modified fast causes a decrease of the peripheral levels of insulin and a resistance to insulin action at the postreceptors sites which is reversed by potassium supply.	Potassium	22-31	insulin	Homo sapiens	145-152
6441716-4	1984	The data suggest that potassium depletion during protein-modified fast causes a decrease of the peripheral levels of insulin and a resistance to insulin action at the postreceptors sites which is reversed by potassium supply.	Potassium	208-217	insulin	Homo sapiens	145-152
3983902-3	1985	The hydrolysis of BzArgpNA by alpha-thrombin was less effective in the presence of sodium ions than in the presence of potassium ions.	Potassium	119-128	coagulation factor II, thrombin	Bos taurus	36-44
3983902-4	1985	The hydrolysis of this latter substrate by beta-thrombin was similar in the presence of either sodium ions or potassium ions.	Potassium	110-119	coagulation factor II, thrombin	Bos taurus	48-56
6392920-7	1984	When PGE2 (10(4) M) was added to the superfusion medium, the potassium-stimulated release of LHRH was significantly enhanced in both groups of animals.	Potassium	61-70	gonadotropin releasing hormone 1	Rattus norvegicus	93-97
6395043-3	1984	The thyroid hormones, the androgens, the growth hormone and the insulin facilitate the penetration of potassium into the cells (rK+ hormones).	Potassium	102-111	insulin	Homo sapiens	64-71
6092045-3	1984	ANF inhibited aldosterone secretion stimulated by 10(-8)M angiotensin II with an IC50 of 1.3 X 10(-9)M. Aldosterone secretion stimulated by 2.9 X 10(-10)M ACTH and by 15 mM potassium was similarly inhibited by ANF.	Potassium	173-182	natriuretic peptide A	Rattus norvegicus	0-3
6388326-5	1984	Cellular uptake of potassium is regulated by insulin, acid-base status, aldosterone, and adrenergic activity.	Potassium	19-28	insulin	Homo sapiens	45-52
6097604-10	1984	Higher total dietary potassium increased total daily milk production.	Potassium	21-30	Weaning weight-maternal milk	Bos taurus	53-57
6489262-1	1984	The studies described herein were designed to determine whether serum potassium modulates the aldosterone secretory response to angiotensin II (Ang II) after nephrectomy.	Potassium	70-79	angiotensinogen	Rattus norvegicus	128-142
6489262-1	1984	The studies described herein were designed to determine whether serum potassium modulates the aldosterone secretory response to angiotensin II (Ang II) after nephrectomy.	Potassium	70-79	angiotensinogen	Rattus norvegicus	144-150
6489262-5	1984	Cells from rats with lower serum potassium levels had lower basal and maximum Ang II-stimulated aldosterone and ED50 values.	Potassium	33-42	angiogenin	Rattus norvegicus	78-81
6489262-9	1984	Additionally, the level of serum potassium of rats before death directly regulates both the sensitivity and magnitude of the aldosterone secretory response to Ang II in vitro.	Potassium	33-42	angiotensinogen	Rattus norvegicus	159-165
6096748-2	1984	Selective effect on potassium-, veratridine- and isoproterenol-stimulated secretion of vasopressin.	Potassium	20-29	arginine vasopressin	Rattus norvegicus	87-98
6152039-0	1984	Decrease of tailed, asymmetric 16S acetylcholinesterase in rat superior cervical ganglion neurons in vitro after potassium depolarization: partial antagonist action of a calcium-channel blocker.	Potassium	113-122	acetylcholinesterase	Rattus norvegicus	35-55
6152039-1	1984	In primary cell cultures of rat superior cervical ganglia the tailed, asymmetric 16S molecular form of acetylcholinesterase (AChE) is preferentially decreased after potassium depolarization.	Potassium	165-174	acetylcholinesterase	Rattus norvegicus	103-123
6152039-1	1984	In primary cell cultures of rat superior cervical ganglia the tailed, asymmetric 16S molecular form of acetylcholinesterase (AChE) is preferentially decreased after potassium depolarization.	Potassium	165-174	acetylcholinesterase	Rattus norvegicus	125-129
6541957-5	1984	The APs from the MBH-cut and control groups released similar amounts of Prl in response to an initial administration of 56 mM potassium (high K+).	Potassium	126-135	prolactin	Rattus norvegicus	72-75
6487306-0	1984	PTH release stimulated by high extracellular potassium is associated with a decrease in cytosolic calcium in bovine parathyroid cells.	Potassium	45-54	parathyroid hormone	Bos taurus	0-3
6389078-6	1984	Renin release is inhibited by high calcium, potassium and angiotensin II.	Potassium	44-53	renin	Homo sapiens	0-5
6486805-5	1984	The affinity of cytochrome P-450i for the substrate, as expressed by the apparent spectral dissociation constant (Ks,app), was 20 microM.	Potassium	114-116	cytochrome P450, family 2, subfamily c, polypeptide 12	Rattus norvegicus	16-33
6741402-7	1984	These results indicate that the intracellular ionic concentrations, probably of potassium ion or of chloride ion, are of importance in the regulation of the synthesis and secretion of decidual Prl in vitro.	Potassium	80-89	prolactin	Homo sapiens	193-196
6149733-2	1984	Cd2+ depressed potassium (K+)-stimulated rise in m.e.p.p.	Potassium	15-24	CD2 antigen	Mus musculus	0-3
6331441-3	1984	The natural 43-73 ANF and the natural 1-73 ANF were equipotent to 48-73 ANF in inhibiting the stimulation of aldosterone secretion produced by angiotensin II with an IC50 of 2 X 10(-9)M. Similar results were obtained with ACTH and potassium.	Potassium	231-240	angiotensinogen	Rattus norvegicus	143-157
6540174-0	1984	Potassium-39 and sodium-23 NMR studies of cation binding to phosvitin.	Potassium	0-9	casein kinase 2 beta	Homo sapiens	60-69
6745606-5	1984	Motilin infusion significantly reduced absorption of water, sodium, potassium, and chloride when a plasmalike electrolyte solution was perfused.	Potassium	68-77	motilin	Homo sapiens	0-7
6745606-6	1984	During perfusion with a bicarbonate-free salt solution, motilin significantly enhanced secretion of water, potassium, and chloride.	Potassium	107-116	motilin	Homo sapiens	56-63
6380335-1	1984	An assessment of continuous glucose-insulin-potassium infusion, and traditional treatment.	Potassium	44-53	insulin	Homo sapiens	36-43
6380335-3	1984	Twelve diabetics received continuous glucose-insulin-potassium (GIK) infusion for at least 4 hours after surgery terminated.	Potassium	53-62	insulin	Homo sapiens	45-52
6329658-0	1984	Role of the renin-angiotensin system in the regulation of late steps in aldosterone biosynthesis by sodium intake of potassium-deficient rats.	Potassium	117-126	renin	Rattus norvegicus	12-17
6086172-1	1984	Growth of cultured cells in low potassium medium has been shown to result in an increase in the number of Na,K-ATPase sites.	Potassium	32-41	ATPase Na+/K+ transporting subunit alpha 1	Gallus gallus	106-117
6086172-11	1984	The reduced contractile response of cells grown in 1 mM extracellular potassium and ouabain (but not isoproterenol) supports the view that elevated intracellular sodium due to Na,K-ATPase inhibition mediates the positive inotropic response to low extracellular potassium and ouabain, probably via augmented transsarcolemmal sodium-calcium exchange.	Potassium	70-79	ATPase Na+/K+ transporting subunit alpha 1	Gallus gallus	176-187
6086172-11	1984	The reduced contractile response of cells grown in 1 mM extracellular potassium and ouabain (but not isoproterenol) supports the view that elevated intracellular sodium due to Na,K-ATPase inhibition mediates the positive inotropic response to low extracellular potassium and ouabain, probably via augmented transsarcolemmal sodium-calcium exchange.	Potassium	261-270	ATPase Na+/K+ transporting subunit alpha 1	Gallus gallus	176-187
6378152-5	1984	Patients with myotonia congenita had elevated potassium levels in the basal state and a greater fall in potassium level during the insulin clamp procedure than controls.	Potassium	104-113	insulin	Homo sapiens	131-138
6329658-7	1984	Angiotensin II seems to be essential for the induction but not for the maintenance of a high activity of the enzyme(s) involved in the conversion of corticosterone to aldosterone during combined sodium and potassium restriction.	Potassium	206-215	angiotensinogen	Rattus norvegicus	0-14
6329658-8	1984	The sensitivity of the zona glomerulosa to the long term stimulatory action of angiotensin II varies with the sodium intake and appears to be regulated by the plasma potassium concentration and unknown other mediators.	Potassium	166-175	angiotensinogen	Rattus norvegicus	79-93
6383811-7	1984	Plasma renin substrate concentration was positively correlated with plasma potassium in both groups (P less than 0.05, P less than 0.001 respectively).	Potassium	75-84	renin	Equus caballus	7-12
6329658-5	1984	Infusion of a high dose of angiotensin II into potassium-deficient rats stimulated aldosterone biosynthesis depending upon the concurrent sodium intake.	Potassium	47-56	angiotensinogen	Rattus norvegicus	27-41
6469707-2	1984	Estimates of fat content were systematically lower when based on a measurement of body density than when based on body water, and were higher still when based on total body potassium.	Potassium	173-182	FAT atypical cadherin 1	Homo sapiens	13-16
6090301-2	1984	It is shown that both progesterone (Ks = 0.45 microM) and testosterone (Ks = 14.7 microM) induce spectral changes at microsomal cytochrome P-450; these spectral effects are not additive and therefore both steroids may act on the same species of cytochrome P-450.	Potassium	36-38	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	128-144
6090301-2	1984	It is shown that both progesterone (Ks = 0.45 microM) and testosterone (Ks = 14.7 microM) induce spectral changes at microsomal cytochrome P-450; these spectral effects are not additive and therefore both steroids may act on the same species of cytochrome P-450.	Potassium	36-38	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	245-261
6373989-6	1984	Plasma aldosterone and 18-hydroxycorticosterone significantly increased with supplement of potassium, and the responses of plasma aldosterone to infusion of angiotensin II were also improved after supplement of potassium.	Potassium	211-220	angiotensinogen	Homo sapiens	157-171
6090301-2	1984	It is shown that both progesterone (Ks = 0.45 microM) and testosterone (Ks = 14.7 microM) induce spectral changes at microsomal cytochrome P-450; these spectral effects are not additive and therefore both steroids may act on the same species of cytochrome P-450.	Potassium	72-74	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	128-144
6090301-2	1984	It is shown that both progesterone (Ks = 0.45 microM) and testosterone (Ks = 14.7 microM) induce spectral changes at microsomal cytochrome P-450; these spectral effects are not additive and therefore both steroids may act on the same species of cytochrome P-450.	Potassium	72-74	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	245-261
6375230-4	1984	Serum potassium levels, however, showed a significant greater decline with infusions of porcine insulin (4.2 +/- 0.1 to 3.5 +/- 0.1 mmol/l) compared with human insulin (4.2 +/- 0.1 to 3.7 +/- 0.1 mmol/l) at 50 mU/kg/h (P less than 0.05).	Potassium	6-15	insulin	Homo sapiens	96-103
6375230-5	1984	Potassium levels were significantly lower during the porcine insulin infusion at 105 and 120 min and at 15 and 30 min after stopping the infusion.	Potassium	0-9	insulin	Homo sapiens	61-68
6375230-8	1984	Thus a small but significant greater decline in potassium levels with similar glucose requirements was found during iv administration of porcine insulin compared with human insulin.	Potassium	48-57	insulin	Homo sapiens	145-152
6202495-7	1984	Isobutylmethylxanthine (0.2 mM) did not affect basal receptor levels and slightly enhanced the GnRH-and potassium-stimulated increase of GnRH-R, whereas the increase caused by (Bu)2cAMP was completely prevented.	Potassium	104-113	gonadotropin releasing hormone receptor	Rattus norvegicus	137-143
6428366-0	1984	[Effects of potassium on renin and aldosterone].	Potassium	12-21	renin	Homo sapiens	25-30
6328983-7	1984	Reduced aldosterone release consequent to the block of angiotensin II formation also contributes to the natriuresis and results in positive potassium balance.	Potassium	140-149	angiotensinogen	Homo sapiens	55-69
6428366-2	1984	Alterations in plasma potassium concentration have opposite and independent effects on renin secretion by the kidney and on aldosterone secretion by the adrenal gland.	Potassium	22-31	renin	Homo sapiens	87-92
6375445-1	1984	Use of continuous intravenous insulin-glucose-potassium infusions.	Potassium	46-55	insulin	Homo sapiens	30-37
6424513-1	1984	The object of this study was to determine whether high doses of insulin administered preventively in combination with glucose and potassium exert a protective effect upon the myocardium.	Potassium	130-139	insulin	Canis lupus familiaris	64-71
6707633-4	1984	Mg2+ incorporation is also promoted by nigericin in the presence of potassium or sodium ions, indicating that Mg2+ accumulation is also dependent upon the transmembrane pH gradient.	Potassium	68-77	mucin 7, secreted	Homo sapiens	0-3
6609717-3	1984	Binding of p-nitrophenyl alpha-D-maltoside to the final complex of red kidney bean alpha-amylase inhibitor and bovine pancreatic alpha-amylase has a beta Ks (Ks") value that is 3.4-fold greater than the Ks (16 mM) of alpha-amylase for p-nitrophenyl alpha-D-maltoside alone.	Potassium	154-156	alpha amylase	Bos taurus	83-96
6609717-3	1984	Binding of p-nitrophenyl alpha-D-maltoside to the final complex of red kidney bean alpha-amylase inhibitor and bovine pancreatic alpha-amylase has a beta Ks (Ks") value that is 3.4-fold greater than the Ks (16 mM) of alpha-amylase for p-nitrophenyl alpha-D-maltoside alone.	Potassium	154-156	alpha amylase	Bos taurus	129-142
6609717-3	1984	Binding of p-nitrophenyl alpha-D-maltoside to the final complex of red kidney bean alpha-amylase inhibitor and bovine pancreatic alpha-amylase has a beta Ks (Ks") value that is 3.4-fold greater than the Ks (16 mM) of alpha-amylase for p-nitrophenyl alpha-D-maltoside alone.	Potassium	154-156	alpha amylase	Bos taurus	129-142
6609717-3	1984	Binding of p-nitrophenyl alpha-D-maltoside to the final complex of red kidney bean alpha-amylase inhibitor and bovine pancreatic alpha-amylase has a beta Ks (Ks") value that is 3.4-fold greater than the Ks (16 mM) of alpha-amylase for p-nitrophenyl alpha-D-maltoside alone.	Potassium	158-160	alpha amylase	Bos taurus	83-96
6609717-3	1984	Binding of p-nitrophenyl alpha-D-maltoside to the final complex of red kidney bean alpha-amylase inhibitor and bovine pancreatic alpha-amylase has a beta Ks (Ks") value that is 3.4-fold greater than the Ks (16 mM) of alpha-amylase for p-nitrophenyl alpha-D-maltoside alone.	Potassium	158-160	alpha amylase	Bos taurus	129-142
6609717-3	1984	Binding of p-nitrophenyl alpha-D-maltoside to the final complex of red kidney bean alpha-amylase inhibitor and bovine pancreatic alpha-amylase has a beta Ks (Ks") value that is 3.4-fold greater than the Ks (16 mM) of alpha-amylase for p-nitrophenyl alpha-D-maltoside alone.	Potassium	158-160	alpha amylase	Bos taurus	129-142
6428366-3	1984	Renin secretion tends to be inhibited by hyperkalemia and stimulated by potassium depletion.	Potassium	72-81	renin	Homo sapiens	0-5
6428366-7	1984	Small changes in plasma potassium have a greater effect on aldosterone than on renin secretion.	Potassium	24-33	renin	Homo sapiens	79-84
6428366-8	1984	In patients with essential hypertension, diuretic induced alterations in serum potassium concentrations may affect both renin and aldosterone secretion.	Potassium	79-88	renin	Homo sapiens	120-125
6428366-1	1984	The renin-aldosterone system contributes to the regulation of arterial pressure and to the maintenance of sodium and potassium balance.	Potassium	117-126	renin	Homo sapiens	4-9
6325278-4	1984	Within an alkali cation series (e.g. NaCH3CO2, NaF, NaCl, NaBr, NaNO3, NaI or a similar potassium series) the affinity decreased with decreasing B coefficient of viscosity.	Potassium	88-97	C-X-C motif chemokine ligand 8	Homo sapiens	47-50
6142577-5	1984	SS-14 had no significant effect on serum potassium or aldosterone but an equimolar dose of SS-28 significantly enhanced the rise in potassium and aldosterone.	Potassium	132-141	somatostatin	Homo sapiens	91-96
6142577-7	1984	Since insulin opposes the increase in serum potassium by stimulating cellular uptake of this cation, the enhanced rise in serum potassium in response to arginine hydrochloride during the SS-28 infusion is likely due to the potent insulin suppressing effect of SS-28.	Potassium	128-137	somatostatin	Homo sapiens	187-192
6142577-7	1984	Since insulin opposes the increase in serum potassium by stimulating cellular uptake of this cation, the enhanced rise in serum potassium in response to arginine hydrochloride during the SS-28 infusion is likely due to the potent insulin suppressing effect of SS-28.	Potassium	128-137	insulin	Homo sapiens	230-237
6142577-7	1984	Since insulin opposes the increase in serum potassium by stimulating cellular uptake of this cation, the enhanced rise in serum potassium in response to arginine hydrochloride during the SS-28 infusion is likely due to the potent insulin suppressing effect of SS-28.	Potassium	128-137	somatostatin	Homo sapiens	260-265
6367486-6	1984	Phospholipase A also plays a regulatory role in phosphatidylcholine metabolism because inhibition of this catabolic enzyme favors phospholipid accretion and kidney growth during potassium depletion, whereas stimulation of the enzyme leads to brisk phospholipid breakdown and a decrease in tissue mass during potassium repletion.	Potassium	178-187	phospholipase A and acyltransferase 1	Rattus norvegicus	0-15
6367486-6	1984	Phospholipase A also plays a regulatory role in phosphatidylcholine metabolism because inhibition of this catabolic enzyme favors phospholipid accretion and kidney growth during potassium depletion, whereas stimulation of the enzyme leads to brisk phospholipid breakdown and a decrease in tissue mass during potassium repletion.	Potassium	308-317	phospholipase A and acyltransferase 1	Rattus norvegicus	0-15
6143631-7	1984	This suggests that adrenaline acts via beta 2 adrenoceptors in man to cause potassium influx and systemic hypokalaemia.	Potassium	76-85	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	39-45
6234067-0	1984	Phenothiazine inhibition of calmodulin stimulates calcium-dependent potassium efflux in human red blood cells.	Potassium	68-77	calmodulin 1	Homo sapiens	28-38
6234067-8	1984	These data suggest that phenothiazines stimulate calcium-dependent potassium loss indirectly by a drug-induced blockage of the calmodulin-activated Ca-ATPase.	Potassium	67-76	calmodulin 1	Homo sapiens	127-137
6728306-1	1984	The results of the present experiments demonstrate that embryonic sympathetic neurons initially selected in culture by nerve growth factor could be subsequently supported by raising potassium concentration of the medium to 35 mM.	Potassium	182-191	nerve growth factor	Gallus gallus	119-138
6367098-2	1984	Furthermore, beta-blockers prevent an increase in plasma renin activity, thereby attenuating diuretic-induced potassium excretion and also the reduction in hypotensive response to the diuretic.	Potassium	110-119	renin	Homo sapiens	57-62
6232955-0	1984	[The role of ATPase subunits from E. coli in hydrogen-potassium exchange].	Potassium	54-63	ATPase	Escherichia coli	13-19
6373592-4	1984	A high potassium diet also increased adrenal capsular renin from 5.27 +/- 0.53 to 39.78 +/- 5.68 ng AI/mg protein/hr, while plasma renin concentration decreased from 7.28 +/- 0.63 in the normal diet to 5.05 +/- 0.60 on the high potassium diet.	Potassium	7-16	renin	Rattus norvegicus	54-59
6539299-0	1984	Atrial natriuretic factor inhibits angiotensin-, norepinephrine-, and potassium-induced vascular contractility.	Potassium	70-79	natriuretic peptide A	Rattus norvegicus	0-25
6364842-0	1984	Insulin-mediated potassium uptake is normal in uremic and healthy subjects.	Potassium	17-26	insulin	Homo sapiens	0-7
6371371-5	1984	Under basal conditions the acute increase in plasma glucose and insulin after glucose loading was accompanied by a significant decrease (P less than 0.01) in plasma cortisol and aldosterone and by a significant increase in plasma renin activity (P less than 0.01); plasma potassium was decreased slightly but not significantly.	Potassium	272-281	insulin	Homo sapiens	64-71
6693420-5	1984	It is thus apparent that: 1) the change in the membrane potential induced by thrombin is directly dependent upon the transmembrane sodium gradient and is primarily due to a dose-dependent sodium uptake by the platelets; and 2) the thrombin-induced secretory processes are dependent upon maintenance of the transmembrane potassium gradients.	Potassium	320-329	coagulation factor II, thrombin	Homo sapiens	77-85
6693420-5	1984	It is thus apparent that: 1) the change in the membrane potential induced by thrombin is directly dependent upon the transmembrane sodium gradient and is primarily due to a dose-dependent sodium uptake by the platelets; and 2) the thrombin-induced secretory processes are dependent upon maintenance of the transmembrane potassium gradients.	Potassium	320-329	coagulation factor II, thrombin	Homo sapiens	231-239
6364673-1	1984	To examine potassium homeostasis in diabetes mellitus, we observed the effect of dietary potassium loading on the renin-angiotensin-aldosterone system and potassium balance in streptozotocin-induced diabetic rats.	Potassium	89-98	renin	Rattus norvegicus	114-119
6364673-1	1984	To examine potassium homeostasis in diabetes mellitus, we observed the effect of dietary potassium loading on the renin-angiotensin-aldosterone system and potassium balance in streptozotocin-induced diabetic rats.	Potassium	89-98	renin	Rattus norvegicus	114-119
6364842-1	1984	We examined the ability of physiological hyperinsulinemia to enhance potassium and glucose uptake by splanchnic and peripheral tissues in 12 chronically uremic subjects by using the euglycemic insulin clamp technique in combination with hepatic and femoral venous catheterization.	Potassium	69-78	insulin	Homo sapiens	46-53
6364842-6	1984	These results indicate that insulin-mediated potassium uptake is not altered by uremia.	Potassium	45-54	insulin	Homo sapiens	28-35
6421178-0	1984	Body potassium by four-pi 40K counting: an anthropometric correction.	Potassium	5-14	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	26-29
6692864-8	1984	We showed elsewhere that at 180 days of age in the C57BL/Ks mouse there was a drastic decrease in slow transport of AChE (G1 and G2 molecular forms) indicating a shift in neuronal metabolism and suggesting that the disease was then more intrinsically neuronal.	Potassium	57-59	acetylcholinesterase	Mus musculus	116-120
6697213-1	1984	The effect of arginine-vasopressin (AVP) on potassium ion-evoked release of [3H]noradrenaline (NA) from rat brainstem slices was investigated.	Potassium	44-57	arginine vasopressin	Rattus norvegicus	36-39
6142098-1	1984	Cysteamine administration to rats results in a marked depletion of hypothalamic somatostatin-14 (SS14) and a decrease of the potassium-evoked in vitro release of SS14 without a significant change in the content or release of somatostatin-28(1-12)-like immunoreactivity (SS28(1-12)-L1).	Potassium	125-134	somatostatin	Rattus norvegicus	162-166
6142098-2	1984	Furthermore, cysteamine enhances the spontaneous release and markedly potentiates the potassium-evoked release of SS14 in the in vitro slice preparation.	Potassium	86-95	somatostatin	Rattus norvegicus	114-118
6325904-4	1984	On exposure to a 1-mM potassium solution, with or without insulin, the cells depolarized to about -50 mV, and became inexcitable.	Potassium	22-31	insulin	Homo sapiens	58-65
6398960-0	1984	Influence of electrolyte depletion and aldosterone on insulin induced changes in plasma concentration and renal excretion of sodium and potassium.	Potassium	136-145	insulin	Homo sapiens	54-61
6398959-0	1984	Effects of insulin on plasma concentration and renal excretion of sodium and potassium.	Potassium	77-86	insulin	Homo sapiens	11-18
6324706-5	1984	The hypertension was associated with a rise in the CSF potassium level.	Potassium	55-64	colony stimulating factor 2	Rattus norvegicus	51-54
6697185-3	1984	The basal efflux and potassium-stimulated release of VIP- and CCK-immunoreactivity was studied in the presence and absence of morphine and D-Ala2-D-Leu5-enkephalin (DADL), agents with relative affinity for the mu and delta receptors, respectively.	Potassium	21-30	vasoactive intestinal peptide	Homo sapiens	53-56
6697185-3	1984	The basal efflux and potassium-stimulated release of VIP- and CCK-immunoreactivity was studied in the presence and absence of morphine and D-Ala2-D-Leu5-enkephalin (DADL), agents with relative affinity for the mu and delta receptors, respectively.	Potassium	21-30	cholecystokinin	Homo sapiens	62-65
6697185-4	1984	The basal efflux of VIP- and CCK-immunoreactivity was not affected by these opiates; however, the potassium-stimulated release of VIP-immunoreactivity was profoundly inhibited in a dose-dependent manner by both morphine (ED50 = 1 X 10(-9) M) and DADL (ED50 = 3.02 X 10(-9) M).	Potassium	98-107	vasoactive intestinal peptide	Homo sapiens	20-23
6697185-4	1984	The basal efflux of VIP- and CCK-immunoreactivity was not affected by these opiates; however, the potassium-stimulated release of VIP-immunoreactivity was profoundly inhibited in a dose-dependent manner by both morphine (ED50 = 1 X 10(-9) M) and DADL (ED50 = 3.02 X 10(-9) M).	Potassium	98-107	cholecystokinin	Homo sapiens	29-32
6697185-4	1984	The basal efflux of VIP- and CCK-immunoreactivity was not affected by these opiates; however, the potassium-stimulated release of VIP-immunoreactivity was profoundly inhibited in a dose-dependent manner by both morphine (ED50 = 1 X 10(-9) M) and DADL (ED50 = 3.02 X 10(-9) M).	Potassium	98-107	vasoactive intestinal peptide	Homo sapiens	130-133
6199591-7	1984	For a given increase in heart rate and cardiac contractility, as measured by the heart rate-corrected duration of total electromechanical systole, which are mainly beta 1-responses, the effects on potassium and norepinephrine were in the order: salbutamol greater than isoproterenol greater than prenalterol.	Potassium	197-206	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	164-170
6477598-3	1984	Besides, the thiol markedly increased not only the Km value for aminopyrine N-demethylase but also the apparent Ks value for aminopyrine binding to the microsomal oxidized cytochrome P-450 by interacting with the cytochrome P-450.	Potassium	112-114	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	172-188
6477598-3	1984	Besides, the thiol markedly increased not only the Km value for aminopyrine N-demethylase but also the apparent Ks value for aminopyrine binding to the microsomal oxidized cytochrome P-450 by interacting with the cytochrome P-450.	Potassium	112-114	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	213-229
6367467-0	1984	Plasma potassium changes in anuric hyperglycemia treated with insulin.	Potassium	7-16	insulin	Homo sapiens	62-69
6367467-7	1984	CONCLUSIONS: When only parenteral insulin is used for treatment and acid-base balances and body weights do not change during treatment in anuric hyperglycemia: a) The change in potassium concentration is dependent on the starting plasma potassium concentration, b) hyperkalemic patients will drop their plasma potassium concentration toward normal, and c) hypokalemic patients may not need potassium replacement.	Potassium	177-186	insulin	Homo sapiens	34-41
6143598-1	1984	The somatostatin content of the nucleus of the solitary tract (NTS) was regionally distributed within the nucleus and a calcium-dependent release of the neuropeptide was evoked by potassium-induced depolarization in vitro.	Potassium	180-189	somatostatin	Homo sapiens	4-16
6389021-0	1984	Kinetics of tryptophanase inactivation/activation by sudden removal/addition of potassium ions with the aid of a crown ether or cryptand.	Potassium	80-89	tryptophan 2,3-dioxygenase	Homo sapiens	12-25
6690484-0	1984	Mechanism of decreased vascular reactivity to angiotensin II in conscious, potassium-deficient rats.	Potassium	75-84	angiotensinogen	Rattus norvegicus	46-60
6199591-8	1984	beta-Blockade with propranolol (nonselective), 80 mg four times a day, or atenolol (beta 1-selective), 100 mg once a day, antagonized the hypokalemic effect of isoproterenol as well as the rise in norepinephrine, but when isoproterenol was infused in doses high enough to overcome the blockade of the heart rate response, the effects on norepinephrine and potassium were abolished by propranolol and not by atenolol.	Potassium	356-365	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	84-90
6320066-0	1983	Opioid peptides selective for mu- and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance.	Potassium	126-135	opioid receptor mu 1	Homo sapiens	30-60
6321936-4	1984	PTH administration increased urinary excretion of cyclic AMP, sodium, potassium, bicarbonate, phosphate clearance, and reabsorption of calcium.	Potassium	70-79	parathyroid hormone	Homo sapiens	0-3
6321936-6	1984	Infusion of PTH to 3 children with hypoparathyroidism produced exaggerated cyclic AMP, phosphate, calcium, potassium, and bicarbonate responses.	Potassium	107-116	parathyroid hormone	Homo sapiens	12-15
6200866-5	1984	The potassium stimulated release of CCK from obese rat hypothalamic tissue was significantly higher than from lean rat hypothalamus (3.62 +/- 0.3 vs. 1.91 +/- 0.3 fmole equivalents CCK-8/mg tissue/10 min).	Potassium	4-13	cholecystokinin	Rattus norvegicus	36-39
6200866-5	1984	The potassium stimulated release of CCK from obese rat hypothalamic tissue was significantly higher than from lean rat hypothalamus (3.62 +/- 0.3 vs. 1.91 +/- 0.3 fmole equivalents CCK-8/mg tissue/10 min).	Potassium	4-13	cholecystokinin	Rattus norvegicus	181-184
6200866-7	1984	However, the potassium stimulated release of CCK and VIP from cortical tissue was the same in all three groups of rats.	Potassium	13-22	cholecystokinin	Rattus norvegicus	45-48
6200866-7	1984	However, the potassium stimulated release of CCK and VIP from cortical tissue was the same in all three groups of rats.	Potassium	13-22	vasoactive intestinal peptide	Rattus norvegicus	53-56
6690484-1	1984	Chronic potassium deficiency in the rat results in a decrease in the pressor sensitivity to exogenous angiotensin II (AII).	Potassium	8-17	angiotensinogen	Rattus norvegicus	102-116
6690484-1	1984	Chronic potassium deficiency in the rat results in a decrease in the pressor sensitivity to exogenous angiotensin II (AII).	Potassium	8-17	angiotensinogen	Rattus norvegicus	118-121
6690484-3	1984	The pressor response to graded doses of AII was 50% less in potassium-deficient than control animals.	Potassium	60-69	angiotensinogen	Rattus norvegicus	40-43
6690484-4	1984	In contrast, the pressor response to graded doses of norepinephrine was preserved in potassium-deficient rats; therefore, the decreased response to AII was not due to a generalized defect in vascular reactivity.	Potassium	85-94	angiotensinogen	Rattus norvegicus	148-151
6690484-9	1984	Furthermore, despite increased circulating AII, there was an increase in AII receptor number in potassium-deficient uterine (308 vs. 147 fmol/mg protein; P less than 0.005) and vascular (470 vs. 316 fmol/mg protein; 0.05 less than P less than 0.1) smooth muscle.	Potassium	96-105	angiotensinogen	Rattus norvegicus	73-76
6690484-11	1984	We conclude that the decrease in angiotensin pressor sensitivity in potassium-deficient rats is mediated by a postreceptor defect since it occurs subsequent to the binding of AII to its vascular smooth muscle receptor.	Potassium	68-77	angiotensinogen	Rattus norvegicus	175-178
6379486-2	1984	In both cases, improvement of serum potassium levels with oral potassium load resulted in an increase in plasma renin activity (PRA) and plasma aldosterone concentration (PAC), a decrease in urinary excretion of prostaglandin E2 (PGE2) and prostaglandin F2 alpha (PGF2 alpha), and an improvement of pressor responsiveness to angiotensin II and norepinephrine.	Potassium	36-45	renin	Homo sapiens	112-117
6379486-2	1984	In both cases, improvement of serum potassium levels with oral potassium load resulted in an increase in plasma renin activity (PRA) and plasma aldosterone concentration (PAC), a decrease in urinary excretion of prostaglandin E2 (PGE2) and prostaglandin F2 alpha (PGF2 alpha), and an improvement of pressor responsiveness to angiotensin II and norepinephrine.	Potassium	36-45	angiotensinogen	Homo sapiens	325-339
6379486-2	1984	In both cases, improvement of serum potassium levels with oral potassium load resulted in an increase in plasma renin activity (PRA) and plasma aldosterone concentration (PAC), a decrease in urinary excretion of prostaglandin E2 (PGE2) and prostaglandin F2 alpha (PGF2 alpha), and an improvement of pressor responsiveness to angiotensin II and norepinephrine.	Potassium	63-72	renin	Homo sapiens	112-117
6379486-2	1984	In both cases, improvement of serum potassium levels with oral potassium load resulted in an increase in plasma renin activity (PRA) and plasma aldosterone concentration (PAC), a decrease in urinary excretion of prostaglandin E2 (PGE2) and prostaglandin F2 alpha (PGF2 alpha), and an improvement of pressor responsiveness to angiotensin II and norepinephrine.	Potassium	63-72	angiotensinogen	Homo sapiens	325-339
6377643-7	1984	During pulsatile LHRH administration, significantly increasing FSH responses were seen in all KS and HP patients, but in only 2 of the 5 CD and in none of the 3 HH patients.	Potassium	94-96	gonadotropin releasing hormone 1	Homo sapiens	17-21
6638193-7	1983	However, juice potassium, which is increased by secretin, was not elevated.	Potassium	15-24	secretin	Rattus norvegicus	48-56
6139416-0	1983	Stimulation of phospholipase A2 and secretion of catecholamines from brain synaptosomes by potassium and A23187.	Potassium	91-100	phospholipase A2 group IB	Rattus norvegicus	15-31
6139416-3	1983	Inhibitors of phospholipase A2 [rho-bromo-phenacylbromide (10 microM), trifluoperazine (3 microM), and quinacrine (3 microM) reduced the potassium-stimulated [3H]catecholamine release from synaptosomes to 78, 39, and 55%, respectively, of depolarized controls.	Potassium	137-146	phospholipase A2 group IB	Rattus norvegicus	14-30
6139416-5	1983	Potassium stimulation of synaptosomes increased the endogenous levels of free arachidonic acid and prostaglandins E2 and F2 alpha.	Potassium	0-9	dihydrolipoamide S-succinyltransferase	Rattus norvegicus	114-129
6652473-6	1983	The addition of potassium (50 mM) and veratridine (7.5 X 10(-5) M) to the superfusate produced significant increases in the levels of VIP-LI in both ventricular and cortical effluents.	Potassium	16-25	vasoactive intestinal peptide	Felis catus	134-137
6652473-7	1983	The potassium evoked release of VIP-LI and CCK-LI was inhibited by the substitution of cobalt (4 mM) for the calcium ion in the perfusion media; basal efflux was not affected.	Potassium	4-13	vasoactive intestinal peptide	Felis catus	32-35
6652473-7	1983	The potassium evoked release of VIP-LI and CCK-LI was inhibited by the substitution of cobalt (4 mM) for the calcium ion in the perfusion media; basal efflux was not affected.	Potassium	4-13	cholecystokinin	Felis catus	43-46
6367910-1	1983	Chronic potassium deficiency in one-kidney one-clip hypertensive dogs significantly reduces blood pressure and plasma potassium, with a simultaneous increase in plasma renin activity.	Potassium	8-17	renin	Canis lupus familiaris	168-173
6685619-4	1983	VIP release from the perifused rat hypothalamus was stimulated by high potassium levels (56 mM).	Potassium	71-80	vasoactive intestinal peptide	Rattus norvegicus	0-3
6376911-5	1983	In contrast to glucose and lipid metabolism, the plasma amino acid and potassium lowering effects of insulin are normal in uremic individuals.	Potassium	71-80	insulin	Homo sapiens	101-108
6360869-7	1983	An alternative mechanism of action is that potassium may alter the activity of the renin-angiotensin system and reduce angiotensin influences on vascular, adrenal, or renal receptors.	Potassium	43-52	renin	Homo sapiens	83-88
6100303-7	1983	We suggest that eag and Sh preferentially disrupt different potassium currents explaining their synergistic interaction.	Potassium	60-69	ether a go-go	Drosophila melanogaster	16-19
6655409-0	1983	Effect of nigericin and varying potassium concentrations on the prolactin-stimulated synthesis of milk fat in explants of mammary alveolar tissue from rabbits.	Potassium	32-41	prolactin	Oryctolagus cuniculus	64-73
6645207-5	1983	In both control and potassium deficient rats, increased fluid intake resulted in increased urine output, decreased urinary and plasma osmolality, and a decrease in plasma AVP.	Potassium	20-29	arginine vasopressin	Rattus norvegicus	171-174
6645207-0	1983	Role of vasopressin in support of blood pressure in potassium deficient rats.	Potassium	52-61	arginine vasopressin	Rattus norvegicus	8-19
6645207-7	1983	To confirm that the decrease in plasma AVP caused the decrease in BP in potassium deficient rats, an AVP pressor antagonist was employed.	Potassium	72-81	arginine vasopressin	Rattus norvegicus	39-42
6355365-8	1983	The effect of turanose and potassium ions on neutral and acid alpha-glucosidase from human urine was characterized.	Potassium	27-36	sucrase-isomaltase	Homo sapiens	62-79
6313451-0	1983	Potassium stimulates parathyroid hormone release in the absence of extracellular calcium.	Potassium	0-9	parathyroid hormone	Bos taurus	21-40
6313451-2	1983	At variance with this mechanism, potassium-evoked parathyroid hormone (PTH) release from perifused dispersed bovine parathyroid cells also occurred in calcium-free medium containing 1 mM EGTA.	Potassium	33-42	parathyroid hormone	Bos taurus	50-69
6628546-0	1983	Neurotensin potentiates the potassium-induced release of endogenous dopamine from rat striatal slices.	Potassium	28-37	neurotensin	Rattus norvegicus	0-11
6628546-3	1983	Neurotensin (2-100 microM) potentiated the potassium-induced release of striatal endogenous DA in a concentration-dependent manner.	Potassium	43-52	neurotensin	Rattus norvegicus	0-11
6888186-3	1983	VIP in chromaffin cells in culture appears to be contained in a secretory granule pool, since it, like methionine-enkephalin (met-enk) was released into the medium after exposure of cells to nicotine, carbachol, veratridine and elevated potassium in a dose-dependent manner.	Potassium	237-246	vasoactive intestinal peptide	Bos taurus	0-3
6355365-6	1983	Under these incubation conditions, potassium ions stimulate the activity of acid alpha-glucosidase and simultaneously inhibit almost completely the residual activity of neutral alpha-glucosidase.	Potassium	35-44	sucrase-isomaltase	Homo sapiens	81-98
6355365-6	1983	Under these incubation conditions, potassium ions stimulate the activity of acid alpha-glucosidase and simultaneously inhibit almost completely the residual activity of neutral alpha-glucosidase.	Potassium	35-44	sucrase-isomaltase	Homo sapiens	177-194
6311248-0	1983	Topological localization of proteolytic sites of sodium and potassium ion stimulated adenosinetriphosphatase.	Potassium	60-69	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	85-108
6193453-0	1983	Dopaminergic mediation of the effect of elevated potassium on the release of pro-opiomelanocortin-derived peptides from the pars intermedia of the rat pituitary.	Potassium	49-58	proopiomelanocortin	Rattus norvegicus	77-97
6194478-2	1983	At concentrations of 20,51, and 100 mM, potassium ions evoked the release of substance P-like immunoreactivity in a dose-dependent manner.	Potassium	40-49	tachykinin precursor 1	Bos taurus	77-88
6194478-3	1983	The drug capsaicin released substance P at concentrations greater than 10(-8) M. Both potassium- and capsaicin-induced release were abolished by omitting calcium ions from the superfusion buffer.	Potassium	86-95	tachykinin precursor 1	Bos taurus	28-39
6853496-8	1983	These results suggest that potassium ion, magnesium ion, and a reticulocyte cytosolic protein(s) stimulate the binding and transport of the ornithine carbamoyltransferase precursor to the mitochondria.	Potassium	27-36	ornithine transcarbamylase	Rattus norvegicus	140-170
6136631-8	1983	In recent studies, other factors including potassium, dopamine and somatostatin have been shown to potentiate or inhibit the actions of angiotensin II on the adrenal gland.	Potassium	43-52	angiotensinogen	Rattus norvegicus	136-150
6134723-8	1983	The purified ATPase, when reconstituted into soybean phospholipid vesicles, exhibits coupling, e.g. the ATPase activity can be stimulated at least 8-fold by valinomycin in the presence of potassium.	Potassium	188-197	ATPase	Enterococcus faecalis	13-19
6134723-8	1983	The purified ATPase, when reconstituted into soybean phospholipid vesicles, exhibits coupling, e.g. the ATPase activity can be stimulated at least 8-fold by valinomycin in the presence of potassium.	Potassium	188-197	ATPase	Enterococcus faecalis	104-110
6302847-1	1983	Electrophysiological analysis of the Drosophila behavioral mutants Eag and Sh and the double mutant Eag Sh indicates that the products of both genes take part in the control of potassium currents in the membranes of both nerve and muscle.	Potassium	177-186	ether a go-go	Drosophila melanogaster	67-70
6305415-0	1983	Light-dependent labeling of the active site of sodium and potassium ion activated adenosinetriphosphatase with the chromium complex of 3"-O-[3-[(4-azido-2-nitrophenyl)amino]-3-tritiopropionyl]adenosine 5"-triphosphate.	Potassium	58-67	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	82-105
6302847-1	1983	Electrophysiological analysis of the Drosophila behavioral mutants Eag and Sh and the double mutant Eag Sh indicates that the products of both genes take part in the control of potassium currents in the membranes of both nerve and muscle.	Potassium	177-186	ether a go-go	Drosophila melanogaster	100-103
6303410-0	1983	Lactoperoxidase-catalyzed iodination of sodium and potassium ion-activated adenosine triphosphatase in the Madin-Darby canine kidney epithelial cell line and canine renal membranes.	Potassium	51-60	lactoperoxidase	Canis lupus familiaris	0-15
6878754-0	1983	Regulation of neurotensin secretion in mammalian C cell lines: potassium and norepinephrine affect the rapid release of the peptide.	Potassium	63-72	neurotensin	Homo sapiens	14-25
6679785-1	1983	Potassium-stimulated uptake of Ca2+ by nerve-ending fractions from rat brain (synaptosomes) is inhibited by morphine and [D-Ala2, D-Leu5]enkephalin.	Potassium	0-9	proenkephalin	Rattus norvegicus	137-147
6339594-4	1983	This was particularly evident in the presence of an increased potassium concentration (6 mM) when insulin hyperpolarized infarcting cells (n = 8) from 73 +/- 6 to 85 +/- 7 mV (p less than 0.01).	Potassium	62-71	insulin	Canis lupus familiaris	98-105
6338733-5	1983	The hypothesis that the calcium-activated potassium permeability is proton sensitive at an intracellular site, a fall in pHi causing a fall in permeability and an increase in pHi causing an increase in permeability, has been used to explain many of the effects observed in this study.	Potassium	42-51	glucose-6-phosphate isomerase 1	Mus musculus	121-124
6838574-0	1983	Co2+ and Mn2+ uptake by crab nerve fibers in resting state and potassium depolarization.	Potassium	63-72	complement C2	Homo sapiens	0-3
6850165-6	1983	Increases in the Mg2+ concentration of the Krebs (to 4.8 mM) depressed responses to potassium and 5-hydroxytryptamine.	Potassium	84-93	mucin 7, secreted	Homo sapiens	17-20
6833836-1	1983	Vigorous exercise has been reported to increase the apparent potassium content of athletes measured by whole body gamma ray scintillation counting of 40K.	Potassium	61-70	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	150-153
6834035-3	1983	Following direct application of potassium to one substantia nigra, changes occurred in the local release of total protein and acetylcholinesterase, but not nonspecific cholinesterases; changes also were observed in both caudate nuclei and the contralateral substantia nigra.	Potassium	32-41	acetylcholinesterase (Cartwright blood group)	Homo sapiens	126-146
6338733-5	1983	The hypothesis that the calcium-activated potassium permeability is proton sensitive at an intracellular site, a fall in pHi causing a fall in permeability and an increase in pHi causing an increase in permeability, has been used to explain many of the effects observed in this study.	Potassium	42-51	glucose-6-phosphate isomerase 1	Mus musculus	175-178
6601233-2	1983	Both the endogenous NADPH oxidase activity and the enzymatic reduction of cytochrome P-450 are inhibited by chloramphenicol treatment, whereas the Km and Ks for ethoxycoumarin and the cumene hydroperoxide- or iodosobenzene-supported deethylation of ethoxycoumarin are unaffected, suggesting that impaired electron transport to cytochrome P-450 may be the cause of the loss of enzymatic activity.	Potassium	154-156	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	74-90
6337046-0	1983	Comparison of the effects of rubidium and potassium on renin secretion from rat kidney slices.	Potassium	42-51	renin	Rattus norvegicus	55-60
6337502-4	1983	Potassium depletion prevented suppression of plasma renin activity (PRA) by dietary NaCl loading and augmented the PRA response to NaCl deprivation.	Potassium	0-9	renin	Homo sapiens	52-57
6337502-9	1983	The results are consistent with the hypothesis that potassium depletion stimulates renin release by inhibiting chloride transport in the loop of Henle.	Potassium	52-61	renin	Homo sapiens	83-88
6132848-3	1983	After insulin withdrawal during the saline infusion, glucose and potassium levels rose markedly (delta maximum: glucose, 12.0 +/- 1.5 mmol/l; potassium, 0.73 +/- 0.12 mmol/l), while glucagon showed a slight, but significant increment (delta maximum: 10.6 +/- 1.0 pmol/ml, p less than 0.05).	Potassium	65-74	insulin	Homo sapiens	6-13
6545081-8	1983	Potassium and magnesium ions, and probably a cytosolic protein(s), were required for the maximal uptake and processing of the ornithine transcarbamylase precursor by the isolated mitochondria.	Potassium	0-9	ornithine transcarbamylase	Rattus norvegicus	126-152
6843120-0	1983	Potassium intake and aldosterone biosynthesis: the role of cytochrome P-450.	Potassium	0-9	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	59-75
6637637-6	1983	Little effect, then, is seen on the level of intracellular potassium ion activity (aiK +) since the membrane potential becomes more permeable to potassium and hyperpolarizes.	Potassium	59-68	aurora kinase A	Homo sapiens	83-86
6545081-13	1983	All these results indicate that potassium and magnesium ions, and probably a cytosolic protein(s), are required for the binding of the ornithine transcarbamylase precursor to the mitochondria or its transport into the organelle.	Potassium	32-41	ornithine transcarbamylase	Rattus norvegicus	135-161
6637637-6	1983	Little effect, then, is seen on the level of intracellular potassium ion activity (aiK +) since the membrane potential becomes more permeable to potassium and hyperpolarizes.	Potassium	145-154	aurora kinase A	Homo sapiens	83-86
6129560-4	1983	These findings indicate that a reduction in potassium permeability in the D cell membrane, as induced by glucose or other stimulants, may be a major step in secretion of somatostatin.	Potassium	44-53	somatostatin	Rattus norvegicus	170-182
6309436-7	1983	The discrepancy in the PRA between primary aldosteronism and Bartter"s syndrome may be due to the effects of potassium repletion on suppressing renin and stimulating aldosterone; while in primary aldosteronism, a mild diuretic effect could explain the rise in PRA.	Potassium	109-118	renin	Homo sapiens	144-149
6131926-4	1983	Intracellular potassium ion activities (aiK) increased significantly from 137.7 +/- 4.0 to 155.6 +/- 3.4 mM-K+.	Potassium	14-23	aurora kinase A	Homo sapiens	40-43
6129560-2	1983	Elevation in the extracellular potassium concentration from 5.5 to 16.5 mM, or 0.2 mM 9-aminoacridine, which decreases potassium permeability in plasma membrane, stimulated the release of somatostatin as well as insulin from the isolated rat pancreatic islets.	Potassium	31-40	somatostatin	Rattus norvegicus	188-200
20487923-6	1983	Potassium stimulated, calcium dependent release of radioactivity from brain slices labelled with [(14)C]EDA in the presence of sodium ions was observed.	Potassium	0-9	ectodysplasin-A	Rattus norvegicus	104-107
6318223-0	1983	Increase in serum potassium caused by beta-2 adrenergic blockade in terminal renal failure: absence of mediation by insulin or aldosterone.	Potassium	18-27	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	38-44
6848991-5	1983	Potassium may reduce blood pressure by increasing sodium excretion, decreasing renin secretion, decreasing sympathetic nerve activity, or directly dilating the arteries.	Potassium	0-9	renin	Homo sapiens	79-84
6636616-1	1983	Total potassium was assayed in 101 patients (58--laryngeal cancer and 43--stomach cancer) on the basis of natural background radiation of 40K in a low background chamber.	Potassium	6-15	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	138-141
6343958-8	1983	A marked increase of the production of Angiotensin-I with increasing sodium concentrations at a low Potassium range was observed and the opposite was true at high Potassium concentrations.	Potassium	100-109	angiotensinogen	Homo sapiens	39-52
6343958-8	1983	A marked increase of the production of Angiotensin-I with increasing sodium concentrations at a low Potassium range was observed and the opposite was true at high Potassium concentrations.	Potassium	163-172	angiotensinogen	Homo sapiens	39-52
6836169-1	1983	Intracellular pH (pHI) of intact rat renal cortex was estimated using [14C]-5,5-dimethyl-2,4-oxazolidinedione and 22Na+ under conditions of metabolic acidosis and alkalosis, potassium depletion and carbonic anhydrase inhibition.	Potassium	174-183	glucose-6-phosphate isomerase	Rattus norvegicus	18-21
7162976-4	1982	The criteria of effectiveness were clinical, electrocardiographic (reversal of the ventricular fibrillation), biochemical (simultaneous and opposite changes in extra- and intracellular potassium levels, suggesting that ATPase inhibition by digitalis is a reversible process) and toxicological: there was an increase in digitoxin serum levels suggesting displacement of the drug from tissue sites to plasma and other extracellular compartments where the Fab fragments are distributed, and Fab-bound digitoxin appeared fairly rapidly in the urine, which suggested shunting of the normal hepatic metabolic pathway.	Potassium	185-194	dynein axonemal heavy chain 8	Homo sapiens	219-225
6184121-5	1982	We have examined the effects of morphine on the potassium-stimulated, calcium-dependent release of SP, CCK and NT from cat hypothalamic slices.	Potassium	48-57	tachykinin precursor 1	Homo sapiens	99-101
6756162-1	1982	The role of angiotensin II in the stimulation of aldosterone biosynthesis by sodium sequestration in potassium-deficient rats was assessed by experiments involving 1-day angiotensin II infusion, converting enzyme inhibition, and bilateral nephrectomy.	Potassium	101-110	angiotensinogen	Rattus norvegicus	12-26
6184121-5	1982	We have examined the effects of morphine on the potassium-stimulated, calcium-dependent release of SP, CCK and NT from cat hypothalamic slices.	Potassium	48-57	cholecystokinin	Homo sapiens	103-106
6295448-0	1982	Exclusive labeling of the extracytoplasmic surface of sodium ion and potassium ion activated adenosinetriphosphatase and a determination of the distribution of surface area across the bilayer.	Potassium	69-78	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	93-116
7172022-2	1982	It proved that in those areas where these peptidergic fibers terminate synaptically a vasopressin and/or oxytocin calcium-dependent release, similar to that in the neurohypophysis, could be evoked by potassium or veratridine.	Potassium	200-209	arginine vasopressin	Rattus norvegicus	86-97
6184121-6	1982	The potassium-stimulated release of SP and CCK was profoundly depressed by the addition of morphine (10(-5) M) in a naloxone-reversible manner.	Potassium	4-13	tachykinin precursor 1	Homo sapiens	36-38
6184121-6	1982	The potassium-stimulated release of SP and CCK was profoundly depressed by the addition of morphine (10(-5) M) in a naloxone-reversible manner.	Potassium	4-13	cholecystokinin	Homo sapiens	43-46
6184121-8	1982	Gel filtration chromatography of the potassium-stimulated release was determined to be isographic with authentic NT, SP and CCK-8, respectively.	Potassium	37-46	tachykinin precursor 1	Homo sapiens	117-119
6184121-8	1982	Gel filtration chromatography of the potassium-stimulated release was determined to be isographic with authentic NT, SP and CCK-8, respectively.	Potassium	37-46	cholecystokinin	Homo sapiens	124-127
6765549-0	1982	Less pronounced changes in serum potassium and epinephrine during hypoglycemia induced by human insulin (recombinant DNA).	Potassium	33-42	insulin	Homo sapiens	96-103
6765549-4	1982	The differences in serum potassium concentrations are caused by a lower epinephrine response to hypoglycemia induced by human insulin in comparison to purified porcine insulin.	Potassium	25-34	insulin	Homo sapiens	126-133
7083193-5	1982	The spectral Ks ratios of the D- and L-enantiomers for P-450scc and PU-450 aromatase are 2.5 and 5, respectively, in the presence of substrate.	Potassium	13-15	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	55-63
6761369-6	1982	Since potassium is known to suppress renin production and stimulate aldosterone secretion, correction of the hypokalemia in this study probably accounts for the decreased PRA and increased plasma aldosterone observed in Bartter"s syndrome.	Potassium	6-15	renin	Homo sapiens	37-42
6132363-3	1982	Both spontaneous and potassium-induced release were inhibited in a dose-response manner by the tripeptide Pro-Leu-Gly-NH2 (PLG, or MIF-1); 0.04 microgram to 1 microgram PLG inhibited the alpha-MSH release but the lowest dose demonstrated a greater inhibitory effect; high concentrations of PLG, on the other hand, did not modify either spontaneous or potassium-evoked alpha-MSH release from the slices.	Potassium	21-30	proopiomelanocortin	Rattus norvegicus	187-196
6132363-3	1982	Both spontaneous and potassium-induced release were inhibited in a dose-response manner by the tripeptide Pro-Leu-Gly-NH2 (PLG, or MIF-1); 0.04 microgram to 1 microgram PLG inhibited the alpha-MSH release but the lowest dose demonstrated a greater inhibitory effect; high concentrations of PLG, on the other hand, did not modify either spontaneous or potassium-evoked alpha-MSH release from the slices.	Potassium	21-30	proopiomelanocortin	Rattus norvegicus	368-377
6293556-0	1982	Monomer of sodium and potassium ion activated adenosinetriphosphatase displays complete enzymatic function.	Potassium	22-31	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	46-69
6293556-1	1982	The distribution of sodium and potassium ion activated adenosinetriphosphatase [(Na+ + K+)-ATPase] among the various oligomeric forms present in a given solution is assessed unambiguously by cross-linking with glutaraldehyde.	Potassium	31-40	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	55-78
6751010-1	1982	The effects of mild acute decreases in plasma potassium induced by standard oral glucose loading (100 g) on plasma aldosterone and renin levels were assessed in 10 patients with primary hyperaldosteronism as compared with 10 normal subjects.	Potassium	46-55	renin	Homo sapiens	131-136
7047682-4	1982	When the potassium in the incubation mixture was replaced with various monovalent cations (Li+, Na+, Cs+, choline, or tetraethylammonium), the magnitude of the MgATP-stimulated release of LHRH was inversely related to the size of the cation; release in the presence of Li+ was 12%, whereas release in the presence of tetraethylammonium was 0% of the total LHRH.	Potassium	9-18	gonadotropin releasing hormone 1	Rattus norvegicus	188-192
7047682-4	1982	When the potassium in the incubation mixture was replaced with various monovalent cations (Li+, Na+, Cs+, choline, or tetraethylammonium), the magnitude of the MgATP-stimulated release of LHRH was inversely related to the size of the cation; release in the presence of Li+ was 12%, whereas release in the presence of tetraethylammonium was 0% of the total LHRH.	Potassium	9-18	gonadotropin releasing hormone 1	Rattus norvegicus	356-360
7051887-1	1982	Use of continuous intravenous infusion of insulin-glucose-potassium solution.	Potassium	58-67	insulin	Homo sapiens	42-49
6761199-0	1982	Regulation of serum potassium during insulin-induced hypoglycemia.	Potassium	20-29	insulin	Homo sapiens	37-44
6180151-5	1982	SP and ERP responses were not abolished by extracellular tetraethylammonium ions (TEA+) but were reduced or eliminated by intracellular TEA+, suggesting that SP reduced a potassium conductance (gK).	Potassium	171-180	tachykinin 1	Mus musculus	158-160
6180151-7	1982	Thus, it was concluded that SP depolarized spinal cord neurons by decreasing a membrane potassium conductance.	Potassium	88-97	tachykinin 1	Mus musculus	28-30
6283027-1	1982	When rat posterior pituitary glands were stimulated by a high concentration of potassium, a peak of cyclic AMP and a peak of cyclic GMP were detected after 0.5 min and 1 min, respectively, whereas the rate of release of vasopressin was maximal only after 2 min.	Potassium	79-88	arginine vasopressin	Rattus norvegicus	220-231
6283914-3	1982	Peritubular potassium concentration (CpK) could be altered by means of double-barreled micropipettes containing a physiologic and a high or low K solution.	Potassium	12-21	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	37-40
7126676-2	1982	It was shown that the investigated complexes inducing a small change in lipid bilayer conductivity and some changes in Na-Ca neuron current characteristics produce essential changes of rapid potassium as well as late potassium current properties.	Potassium	191-200	nascent polypeptide associated complex subunit alpha	Homo sapiens	119-124
7126676-2	1982	It was shown that the investigated complexes inducing a small change in lipid bilayer conductivity and some changes in Na-Ca neuron current characteristics produce essential changes of rapid potassium as well as late potassium current properties.	Potassium	217-226	nascent polypeptide associated complex subunit alpha	Homo sapiens	119-124
6751813-4	1982	The lowest level of potassium (3.39 +/- 0.09 mval/l) is observed 45 min following insulin application.	Potassium	20-29	insulin	Homo sapiens	82-89
6761199-2	1982	Under these conditions (minimal plasma glucose 27.4 +/- 1 mg/dl) the decrease of serum potassium concentration (0.9 mVal/L) is mediated by two mechanisms: insulin-induced (0.48 mVal/L) and epinephrine-induced (0.42 mVal/L) cellular uptake of potassium.	Potassium	87-96	insulin	Homo sapiens	155-162
6761199-2	1982	Under these conditions (minimal plasma glucose 27.4 +/- 1 mg/dl) the decrease of serum potassium concentration (0.9 mVal/L) is mediated by two mechanisms: insulin-induced (0.48 mVal/L) and epinephrine-induced (0.42 mVal/L) cellular uptake of potassium.	Potassium	242-251	insulin	Homo sapiens	155-162
6284206-0	1982	Determination of the distribution of sodium and potassium ion activated adenosinetriphosphatase among the various oligomers formed in solutions of nonionic detergents.	Potassium	48-57	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	72-95
6896838-6	1982	In rats, the addition of potassium (40 mM in excess) resulted in a 138% and 46% increase in the levels of CCK and VIP, respectively above resting levels (3.7 +/- 1.2 fmol/ml/10 min and 1.7 +/- 0.5 fmol/ml/10 min, respectively).	Potassium	25-34	cholecystokinin	Rattus norvegicus	106-109
6896838-6	1982	In rats, the addition of potassium (40 mM in excess) resulted in a 138% and 46% increase in the levels of CCK and VIP, respectively above resting levels (3.7 +/- 1.2 fmol/ml/10 min and 1.7 +/- 0.5 fmol/ml/10 min, respectively).	Potassium	25-34	vasoactive intestinal peptide	Rattus norvegicus	114-117
6124125-0	1982	Potassium homeostasis during hyperinsulinemia: effect of insulin level, beta-blockade, and age.	Potassium	0-9	insulin	Homo sapiens	34-41
6124125-6	1982	These results suggest the presence of a regulatory mechanism influencing insulin-mediated alterations in plasma potassium.	Potassium	112-121	insulin	Homo sapiens	73-80
7085915-3	1982	In the patients with renal failure, there was a positive correlation between raised CSF and plasma potassium concentrations.	Potassium	99-108	colony stimulating factor 2	Homo sapiens	84-87
7044145-0	1982	Effects of acute potassium infusions with salts other than chloride on plasma renin activity.	Potassium	17-26	renin	Rattus norvegicus	78-83
6180215-15	1982	In conclusion, the decrease in renal blood flow and the increase in renal vascular resistance in potassium depletion is mediated by angiotensin II and a product of prostaglandin endoperoxide metabolism, most likely, thromboxane.	Potassium	97-106	angiotensinogen	Rattus norvegicus	132-146
7121714-4	1982	When gamma-vinyl GABA (RMI 71754), an inhibitor of GABA-T was injected into rats (750 mg/kg) and synaptosomes prepared the potassium-evoked release of GABA was increased 3-fold compared to controls.	Potassium	123-132	4-aminobutyrate aminotransferase	Rattus norvegicus	51-57
7084109-0	1982	Potassium stimulates parathyroid hormone release from perifused parathyroid cells.	Potassium	0-9	parathyroid hormone	Bos taurus	21-40
7084109-4	1982	High potassium (60 mM) promptly stimulated PTH secretion at 1.5 mM calcium.	Potassium	5-14	parathyroid hormone	Bos taurus	43-46
6954503-0	1982	Intracellular potassium: 40K as a primordial gene irradiator.	Potassium	14-23	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	25-28
6954503-1	1982	We have been interested in the possibility that the low energy electrons (Auger and Coster-Kronig) emitted after the electron capture decay of 40K may have highly localized radiochemical effects on the genetic material--effects dependent upon the intracellular locus of potassium.	Potassium	270-279	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	143-146
6284206-1	1982	Sodium and potassium ion activated adenosinetriphosphatase [(Na+ + K+)-ATPase] can be dispersed from the membrane-bound state, with the stable retention of the capacity to display (Na+ + K+)-ATPase activity, by treatment with solutions of a homogeneous, nonionic detergent, octaethylene glycol dodecyl ether.	Potassium	11-20	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	35-58
6284173-8	1982	The present results indicate that (1) calcium influx is an essential event in the aldosterone stimulating action of angiotensin II, potassium ions, ACTH and cyclic AMP; (2) stimulation by angiotensin II and potassium ions are completely dependent on calmodulin; (3) stimulation by ACTH and cyclic AMP is mediated by calmodulin-dependent and independent mechanisms.	Potassium	207-216	transmembrane serine protease 5	Rattus norvegicus	164-167
6281634-11	1982	Potassium delays the increase of plasma renin activity after furosemide and propranolol inhibits the furosemide-induced renin release, both without impairing aldosterone secretion.	Potassium	0-9	renin	Homo sapiens	40-45
6281634-11	1982	Potassium delays the increase of plasma renin activity after furosemide and propranolol inhibits the furosemide-induced renin release, both without impairing aldosterone secretion.	Potassium	0-9	renin	Homo sapiens	120-125
6284173-8	1982	The present results indicate that (1) calcium influx is an essential event in the aldosterone stimulating action of angiotensin II, potassium ions, ACTH and cyclic AMP; (2) stimulation by angiotensin II and potassium ions are completely dependent on calmodulin; (3) stimulation by ACTH and cyclic AMP is mediated by calmodulin-dependent and independent mechanisms.	Potassium	207-216	calmodulin 1	Rattus norvegicus	250-260
6284173-8	1982	The present results indicate that (1) calcium influx is an essential event in the aldosterone stimulating action of angiotensin II, potassium ions, ACTH and cyclic AMP; (2) stimulation by angiotensin II and potassium ions are completely dependent on calmodulin; (3) stimulation by ACTH and cyclic AMP is mediated by calmodulin-dependent and independent mechanisms.	Potassium	207-216	transmembrane serine protease 5	Rattus norvegicus	297-300
6284173-8	1982	The present results indicate that (1) calcium influx is an essential event in the aldosterone stimulating action of angiotensin II, potassium ions, ACTH and cyclic AMP; (2) stimulation by angiotensin II and potassium ions are completely dependent on calmodulin; (3) stimulation by ACTH and cyclic AMP is mediated by calmodulin-dependent and independent mechanisms.	Potassium	207-216	calmodulin 1	Rattus norvegicus	316-326
7041843-0	1982	Racial difference in salivary sodium-potassium ratio in low renin essential hypertension.	Potassium	37-46	renin	Homo sapiens	60-65
7092924-7	1982	The apparent spectral binding constants (Ks values) for the Type I site (but not the Type RI site) were closely associated with the Ki and I50 values for the inhibition of cytochrome P-450-dependent monooxygenation.	Potassium	41-43	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	172-188
7076344-0	1982	The influence of a single dose of vasopressin analogs on human renal potassium excretion.	Potassium	69-78	arginine vasopressin	Homo sapiens	34-45
7047274-2	1982	Glucose plus arginine and potassium produced subnormal insulin responses in all three diabetic sublines, whereas theophylline induced "normal" or above normal insulin responses.	Potassium	26-35	insulin	Cricetulus griseus	55-62
6283190-6	1982	These results suggest that (1) acute potassium loading causes a significant increase in the plasma ACTH level and increased levels of adrenocortical hormones may be produced  by increased ACTH secretion, and (2) it may be considered that a part of the increased level of plasma aldosterone following acute potassium loading may arise from increased ACTH secretion in EH.	Potassium	37-46	proopiomelanocortin	Homo sapiens	99-103
6283190-6	1982	These results suggest that (1) acute potassium loading causes a significant increase in the plasma ACTH level and increased levels of adrenocortical hormones may be produced  by increased ACTH secretion, and (2) it may be considered that a part of the increased level of plasma aldosterone following acute potassium loading may arise from increased ACTH secretion in EH.	Potassium	37-46	proopiomelanocortin	Homo sapiens	188-192
6283190-0	1982	Response of plasma ACTH and adrenocortical hormones to potassium loading in essential hypertension.	Potassium	55-64	proopiomelanocortin	Homo sapiens	19-23
6283190-6	1982	These results suggest that (1) acute potassium loading causes a significant increase in the plasma ACTH level and increased levels of adrenocortical hormones may be produced  by increased ACTH secretion, and (2) it may be considered that a part of the increased level of plasma aldosterone following acute potassium loading may arise from increased ACTH secretion in EH.	Potassium	37-46	proopiomelanocortin	Homo sapiens	188-192
6756014-4	1982	By means of exogenous high insulin and potassium supply with glucose infusion the potassium-shifting is improved, the FFA-level is lowered and the incidence of arrhythmias is reduced as sinusrhythm is induced.	Potassium	82-91	insulin	Homo sapiens	27-34
6462181-1	1982	It has been shown that the induction of earlier described system of potassium-dependent transport of hydrogen ions in mitochondria at low pH values of the incubation medium is inhibited by the inhibitors of mitochondria respiratory chain and ATPase.	Potassium	68-77	dynein axonemal heavy chain 8	Homo sapiens	242-248
6462181-3	1982	The uncoupler (FCCP) turns the effect of ATPase inhibitors to the efflux of potassium ions and acceleration of mitochondria respiration under experimental conditions.	Potassium	76-85	dynein axonemal heavy chain 8	Homo sapiens	41-47
6462181-5	1982	The data obtained are explained in terms of the postulate that under experimental conditions along with the system of potassium-dependent ion transport there appears leakage of protons through the ATPase channel.	Potassium	118-127	dynein axonemal heavy chain 8	Homo sapiens	197-203
7040195-4	1982	Human insulin produced a significantly smaller decrease in serum potassium (2p less than 0.01).	Potassium	65-74	insulin	Homo sapiens	6-13
7043022-0	1982	Effect of angiotensin converting enzyme inhibitor on serum aldosterone and potassium level.	Potassium	75-84	angiotensin I converting enzyme	Homo sapiens	10-39
7043022-6	1982	It is suggested that reduction in aldosterone level and potassium retention were caused by blockade of angiotensin II formation by captopril, but the potassium retention was additionally influenced by renal impairment.	Potassium	56-65	angiotensinogen	Homo sapiens	103-117
7047719-0	1982	The effects of antidiuretic hormone and state of potassium balance on the renin-angiotensin system in rats with diabetes insipidus.	Potassium	49-58	renin	Rattus norvegicus	74-79
7047719-2	1982	The influence of ADH and the state of potassium balance on the renin-angiotensin system was studied in rats with hereditary diabetes insipidus (DI rats).	Potassium	38-47	renin	Rattus norvegicus	63-68
7047719-17	1982	Plasma renin concentration was significantly lower in ADH-treated than in untreated DI rats on a high potassium intake, suggesting that the inhibitory effects of ADH and potassium are additive.	Potassium	102-111	renin	Rattus norvegicus	7-12
7047719-17	1982	Plasma renin concentration was significantly lower in ADH-treated than in untreated DI rats on a high potassium intake, suggesting that the inhibitory effects of ADH and potassium are additive.	Potassium	170-179	renin	Rattus norvegicus	7-12
7054638-4	1982	Neurotensin 2 and 10 microM, doses without effect on the spontaneous release of NA, potentiated the potassium-induced release of this amine.	Potassium	100-109	neurotensin	Rattus norvegicus	0-11
7045869-0	1982	Acetylcholine, melatonin, and potassium depolarization stimulate release of luteinizing hormone-releasing hormone from rat hypothalamus in vitro.	Potassium	30-39	gonadotropin releasing hormone 1	Rattus norvegicus	76-113
7045869-4	1982	Potassium depolarization, effected by the addition of 56 mM potassium chloride to the incubation medium, caused a marked stimulation in LH-RH release, but only in the presence of calcium.	Potassium	0-9	gonadotropin releasing hormone 1	Rattus norvegicus	136-141
6123097-1	1982	The release of vasoactive intestinal peptide (VIP) from rat brain cortical and amygdala slices was studied by using various depolarizing agents such as potassium (K+), veratridine (VER) and batrachotoxin (BTX).	Potassium	152-161	vasoactive intestinal peptide	Rattus norvegicus	15-44
6123097-1	1982	The release of vasoactive intestinal peptide (VIP) from rat brain cortical and amygdala slices was studied by using various depolarizing agents such as potassium (K+), veratridine (VER) and batrachotoxin (BTX).	Potassium	152-161	vasoactive intestinal peptide	Rattus norvegicus	46-49
6123097-4	1982	When the incubation medium did not contain any calcium, the action of potassium on the release of VIP was suppressed.	Potassium	70-79	vasoactive intestinal peptide	Rattus norvegicus	98-101
7042430-7	1982	Since the diabetic subjects were found to have an intact insulin response to the glucose load, it is suggested that resistance to insulin-stimulated potassium uptake into cells might be involved in the pathogenesis of the paradoxical hyperkalaemia induced by acute hyperglycaemia.	Potassium	149-158	insulin	Homo sapiens	130-137
6123453-1	1982	This study was made to investigate the mechanisms of the changes in serum potassium during a period of insulin-induced hypoglycemia.	Potassium	74-83	insulin	Homo sapiens	103-110
6123453-2	1982	The following experiments were performed: I) A relationship was observed between the amount of insulin dosage and the levels of serum potassium, blood sugar, and plasma cyclic AMP or plasma cyclic GMP in normal controls and rats.	Potassium	134-143	insulin	Homo sapiens	95-102
6123453-11	1982	The results obtained were as follows: 1) There was a significant logarithmic dose-response relationship between insulin dose and maximum per cent decrease in serum potassium, and maximum per cent increase in plasma cyclic AMP.	Potassium	164-173	insulin	Homo sapiens	112-119
6123453-12	1982	(p less than 0.02 approximately 0.01) 2) A significant positive correlation was observed between the maximum per cent decrease in serum potassium and the maximum per cent increase in plasma cyclic AMP during the period of insulin-induced hypoglycemia.	Potassium	136-145	insulin	Homo sapiens	222-229
6123453-17	1982	These results may indicate that a decrease of serum potassium levels during the period of insulin-induced hypoglycemia in both the early and late phases is caused by different mechanisms.	Potassium	52-61	insulin	Homo sapiens	90-97
6123453-19	1982	It was suggested that beta-adrenoreceptor play a role in a decrease of serum potassium, especially 30 minutes after a injection of insulin.	Potassium	77-86	insulin	Homo sapiens	131-138
6119599-0	1982	Regulation of tyrosine hydroxylase activity in retinal cell suspensions: effects of potassium and 8-bromo cyclic AMP.	Potassium	84-93	tyrosine hydroxylase	Rattus norvegicus	14-34
6307553-4	1982	ACE was inversely related to systolic and mean arterial blood pressures, inversely to serum sodium and urinary potassium and directly to serum potassium levels.	Potassium	111-120	angiotensin I converting enzyme	Homo sapiens	0-3
6127053-3	1982	Saturation constants (Ks) of P17 with acetate, arginine, aspartate, glutamate, lactate, succinate, malonate, p-hydroxybenzoate and glucose were all below 1 microM.	Potassium	22-24	family with sequence similarity 72 member B	Homo sapiens	29-32
7055905-1	1982	Results obtained with a potentiometric analyzer, NOVA 1, specific for sodium and potassium, were compared with those by flame photometry.	Potassium	81-90	NOVA alternative splicing regulator 1	Homo sapiens	49-55
6307553-4	1982	ACE was inversely related to systolic and mean arterial blood pressures, inversely to serum sodium and urinary potassium and directly to serum potassium levels.	Potassium	143-152	angiotensin I converting enzyme	Homo sapiens	0-3
6754152-5	1982	Serum potassium levels were lower, but urinary potassium excretion was higher in low renin patients.	Potassium	47-56	renin	Homo sapiens	85-90
6754154-0	1982	The salivary sodium/potassium ratio in hypertension: relation to race and plasma renin activity.	Potassium	20-29	renin	Homo sapiens	81-86
6183051-12	1982	Endogenous 5-HT and TRH release from slices of lumbar cord was enhanced by high potassium.	Potassium	80-89	thyrotropin releasing hormone	Rattus norvegicus	20-23
7033089-4	1981	Human insulin produced a significantly smaller decrease in serum potassium (2p less than 0.01).	Potassium	65-74	insulin	Homo sapiens	6-13
7079557-2	1982	Renal arterial infusion of BK (3 micrograms/min) in control dogs produced a sustained increase in urine flow rate (V), sodium excretion (UNaV), potassium excretion (UKV), and renal plasma flow (RPF) without a consistent change in glomerular filtration rate (GFR) or renin secretion rate (RSR).	Potassium	144-153	kininogen 1	Canis lupus familiaris	27-29
6124064-6	1982	Ks values for the interaction of ranitidine with cytochrome P-450 (not reduced), calculated from double reciprocal plots, were in the range 1.4-2.8 mM.	Potassium	0-2	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	49-65
6223136-1	1982	CaATPase of human erythrocyte membranes exists in both a basal and a calmodulin-activated form, each of which can be further activated by monovalent ions such as sodium, potassium or lithium.	Potassium	170-179	calmodulin 1	Homo sapiens	69-79
6798509-0	1981	Calcium dependency of potassium-stimulated thyrotropin-releasing hormone secretion from rat neurohypophysis in vitro.	Potassium	22-31	thyrotropin releasing hormone	Rattus norvegicus	43-72
7026126-8	1981	There were significant associations between ileal-fluid potassium concentration and plasma renin activity or renal aldosterone excretion.	Potassium	56-65	renin	Homo sapiens	91-96
7298807-0	1981	Effect of potassium on PTH secretion from dispersed bovine parathyroid cells.	Potassium	10-19	parathyroid hormone	Bos taurus	23-26
7298807-1	1981	The effects of potassium on PTH secretion were studied in dispersed bovine parathyroid cells.	Potassium	15-24	parathyroid hormone	Bos taurus	28-31
7298807-2	1981	Removal of extracellular potassium markedly inhibited low calcium-stimulated PTH release.	Potassium	25-34	parathyroid hormone	Bos taurus	77-80
6170855-0	1981	Capsaicin and potassium evoked substance P release from the nucleus tractus solitarius and spinal trigeminal nucleus in vitro.	Potassium	14-23	tachykinin precursor 1	Homo sapiens	31-42
7028620-11	1981	Increasing Krebs potassium (50 mM) increased basal renin fourfold (14 ng AI) while the absolute increase from basal due to ISO remained the same (23 ng AI).	Potassium	17-26	renin	Rattus norvegicus	51-56
7298111-5	1981	In spite of the massive diuretic effect, potassium loading significantly attenuated the increased plasma renin activity (PRA) induced by renal artery constriction, while it further enhanced the increased plasma aldosterone concentration (PAC) in two-kidney, one clip Goldblatt hypertensive rats.	Potassium	41-50	renin	Rattus norvegicus	105-110
7197759-3	1981	Both spontaneous and potassium-induced alpha-MSH release compared to spontaneous release.	Potassium	21-30	proopiomelanocortin	Rattus norvegicus	39-48
7197759-4	1981	Removal of calcium from the superfusion medium abolished the potassium-evoked release of alpha-MSH.	Potassium	61-70	proopiomelanocortin	Rattus norvegicus	89-98
7295860-2	1981	In two normaldosteronemic insulin-dependent diabetic patients during high sodium intake and insulin withdrawal infusion of hypertonic glucose induced a paradoxical elevation of serum potassium levels, while no such abnormalities were found in two other diabetics despite of lower plasma aldosterone levels.	Potassium	183-192	insulin	Homo sapiens	26-33
7295860-2	1981	In two normaldosteronemic insulin-dependent diabetic patients during high sodium intake and insulin withdrawal infusion of hypertonic glucose induced a paradoxical elevation of serum potassium levels, while no such abnormalities were found in two other diabetics despite of lower plasma aldosterone levels.	Potassium	183-192	insulin	Homo sapiens	92-99
7311167-5	1981	In the strips which reached a steady state 2 hr after administration of potassium, phospholipase A2 and bradykinin produced marked oscillations.	Potassium	72-81	phospholipase A2 group IB	Homo sapiens	83-99
7311167-5	1981	In the strips which reached a steady state 2 hr after administration of potassium, phospholipase A2 and bradykinin produced marked oscillations.	Potassium	72-81	kininogen 1	Homo sapiens	104-114
6266686-9	1981	Thus hypertensives with decreased aldosterone responsiveness to infused AII also had decreased responsiveness to infused ACTH and potassium, suggesting that their defect lies in the intracellular aldosterone biosynthetic pathway.	Potassium	130-139	angiotensinogen	Homo sapiens	72-75
16661950-2	1981	Potassium was the preferred monovalent cation for stimulating the ATPase above the Mg(2+)-activated level.	Potassium	0-9	ATPase	Zea mays	66-72
7320897-19	1981	In a calcium-free high-potassium (126 mM) solution, readmitting calcium produced contraction; VIP inhibited this contraction.	Potassium	23-32	VIP peptides	Oryctolagus cuniculus	94-97
6268928-6	1981	Several hormones (insulin, aldosterone, catecholamines, glucagon, and growth hormone) may have roles in internal potassium balance.	Potassium	113-122	insulin	Homo sapiens	18-25
6268928-6	1981	Several hormones (insulin, aldosterone, catecholamines, glucagon, and growth hormone) may have roles in internal potassium balance.	Potassium	113-122	growth hormone 1	Homo sapiens	70-84
16661950-4	1981	A K(m) of 0.28 millimolar Mg(2+)-ATP was determined for the K(+)-ATPase, and the principal effect of potassium was on the V(max) for ATP hydrolysis.	Potassium	101-110	ATPase	Zea mays	65-71
6114785-1	1981	Calcium-dependent potassium-evoked release of somatostatin-like immuno-reactivity (SSLI) and preloaded [3H]noradrenaline ([3H]NA) could be demonstrated simultaneously from slices of rat cerebral cortex, globus pallidus and trigeminal nucleus.	Potassium	18-27	somatostatin	Rattus norvegicus	46-58
7015510-1	1981	Methionine enkephalin release was evoked by depolarization of slices from rat striatum with potassium.	Potassium	92-101	proenkephalin	Rattus norvegicus	11-21
6114785-3	1981	Both morphine (10 microM) and dopamine (50 microM) significantly inhibited the potassium-evoked release of SS from the cerebral cortex, without affecting its basal release.	Potassium	79-88	somatostatin	Rattus norvegicus	107-109
6786952-6	1981	Those patients receiving insulin demonstrated a gain of total body potassium (p less than 0.001).	Potassium	67-76	insulin	Homo sapiens	25-32
7019208-8	1981	An analysis of the inhibitory effect of potassium ion on the rate and extent of inactivation of D-serine dehydratase by alkylamines indicated that K+ binding increased the affinity of the enzyme for its cofactor by at least 13-fold.	Potassium	40-49	serine racemase	Homo sapiens	96-116
7270848-6	1981	It is concluded that Nova 1, if kept in working order, can provide potassium estimations quickly and accurately.	Potassium	67-76	NOVA alternative splicing regulator 1	Homo sapiens	21-27
7018811-2	1981	Potassium infusion causes an increase in immunoreactive insulin levels in dogs, but either a small (30%) or no increase in humans.	Potassium	0-9	insulin	Canis lupus familiaris	56-63
6165445-0	1981	Substance P decreases a potassium conductance of spinal cord neurons in cell culture.	Potassium	24-33	tachykinin 1	Mus musculus	0-11
6171537-2	1981	Potassium cationization field desorption mass spectrometry of some penta- and hexapeptides derived from substance P.	Potassium	0-9	tachykinin precursor 1	Homo sapiens	104-115
6171537-3	1981	In this article we present preliminary results of the application of potassium cationized field desorption mass spectrometry as an additional technique for the elucidation of structure and evaluation of purity of oligopeptides such as C-terminal penta- and hexapeptide analogs of substance P.	Potassium	69-78	tachykinin precursor 1	Homo sapiens	280-291
7021590-1	1981	Although dietary potassium deficiency (KD) results in an increase in plasma renin activity (PRA), the mechanism of this effect has not been elucidated.	Potassium	17-26	renin	Rattus norvegicus	76-81
6259213-13	1981	This is the first evidence that potassium modulates angiotensin II receptors independently of changes in angiotensin II blood levels.	Potassium	32-41	angiotensinogen	Rattus norvegicus	52-66
7021278-11	1981	Insulin levels, similar to those found after a meal, rapidly reversed the effects of glucagon on non-esterified fatty acid, glucose and potassium.	Potassium	136-145	insulin	Homo sapiens	0-7
6111930-6	1981	Several hormones, including insulin and epinephrine, have been shown to play an important role in the maintenance of normal extrarenal potassium metabolism.	Potassium	135-144	insulin	Homo sapiens	28-35
6261818-11	1981	The enzyme-potassium complex, in turn, binds Mg2+ in a dead-end fashion.	Potassium	11-20	mucin 7, secreted	Homo sapiens	45-48
6261874-5	1981	Neurotensin release was stimulated by dibutyryl cyclic AMP (10(-4) M) and by depolarizing concentrations of potassium.	Potassium	108-117	neurotensin	Rattus norvegicus	0-11
7009278-4	1981	The paradoxical rise in serum potassium with hyperglycemia was corrected in all by concomitant administration of insulin or pretreatment with a mineralocorticoid.	Potassium	30-39	insulin	Homo sapiens	113-120
7242525-2	1981	Optimal potassium concentration for the total protein-synthesizing activity and for the synthesis of immunoreactive ceruloplasmin was 96 and 186 mM respectively.	Potassium	8-17	ceruloplasmin	Rattus norvegicus	116-129
7241088-13	1981	ks is much smaller for PV-Lac than for valinomycin and thus limits the efficiency with which the carrier is able to translocate cations across the membrane.	Potassium	0-2	lactase	Homo sapiens	26-29
7242525-4	1981	Immunoprecipitated ceruloplasmin that was synthesized at optimal potassium concentration was a homogeneous polypeptide of a molecular weight about 84 kD.	Potassium	65-74	ceruloplasmin	Rattus norvegicus	19-32
6259537-4	1981	(H+ + K+)ATPase, which has only been found at the secretory surface of the parietal cell, catalyses a one-to-one exchange of protons and potassium ions.	Potassium	137-146	ATPase H+/K+ transporting subunit alpha	Sus scrofa	1-15
6256154-4	1981	In collagenase-dispersed glomerulosa cells from adrenals of ACTH-treated rats, angiotensin II receptors were markedly decreased, as were the in vitro aldosterone responses to angiotensin II, ACTH, 8-bromo-cAMP, and potassium.	Potassium	215-224	angiotensinogen	Rattus norvegicus	79-93
7471878-0	1981	Blood potassium measurements during CPR.	Potassium	6-15	cytochrome p450 oxidoreductase	Homo sapiens	36-39
7011086-3	1981	The relevance of the concept of glucose-induced hyperkalaemia is discussed and it is suggested that intravenous infusion of insulin during and after operation might have decreased the rises in serum potassium.	Potassium	199-208	insulin	Homo sapiens	124-131
7006412-6	1981	According to these observations, experimental edema stimulates late steps of aldosterone biosynthesis in potassium-depleted rats by mediation of the kidneys, most likely through the renin-angiotensin system.	Potassium	105-114	renin	Rattus norvegicus	182-187
7463074-2	1981	Only 2-3% of the total tissue stores of enkephalin could be released by potassium-depolarization; similar percentages were released from globus pallidus, thalamus, and nucleus accumbens.	Potassium	72-81	proenkephalin	Rattus norvegicus	40-50
6174024-3	1981	At higher concentrations of sodium and potassium ions, ATPase of normal and nitrofurantoin resistant Vibrio el tor responded quite differently.	Potassium	39-48	dynein axonemal heavy chain 8	Homo sapiens	55-61
7007090-0	1981	[Effect of insulin and hydrocortisone on the concentration of sodium and potassium ions in nucleated and non-nucleated erythrocytes of chickens and rats].	Potassium	73-82	insulin	Gallus gallus	11-18
6973460-7	1981	The excretion of potassium was increased after both compounds, the highest value being found after subcutaneous administration of [8-lysine]vasopressin.	Potassium	17-26	arginine vasopressin	Rattus norvegicus	140-151
6786910-3	1981	It is concluded that CA3 neurons generate at least two types of hyperpolarization: one resulting from a calcium-mediated potassium conductance and the other from increased conductance to chloride.	Potassium	121-130	carbonic anhydrase 3	Homo sapiens	21-24
7328633-0	1981	Some properties of KCl-filled microelectrodes: correlation of potassium "leakage" with tip resistance.	Potassium	62-71	TOR signaling pathway regulator	Homo sapiens	87-90
7021949-0	1981	[Treatment of recent myocardial infarct with infusions of potassium, glucose and insulin (PGI).	Potassium	58-67	glucose-6-phosphate isomerase	Homo sapiens	90-93
6941816-2	1980	It was found that pepstatin, a specific inhibitor of carboxylic proteinases, inhibits this activity of cathepsins D. Interaction of chicken liver cathepsin D with human plasma substrate, which is possibly a low molecular weight kininogen (Ks = 1.3.10(-7) M) results in a production of the bradikinin analog methionyl-lysyl-bradikinin.	Potassium	239-241	cathepsin D	Gallus gallus	146-157
7009427-1	1981	Relationship between angiotensin II and body sodium and potassium on correction of hypertension by captopril and subsequent surgery.	Potassium	56-65	angiotensinogen	Homo sapiens	21-35
7459350-1	1980	5-(n-Alk(en)yl) resorcinols can induce potassium release from liposomes and erythrocytes.	Potassium	39-48	ALK receptor tyrosine kinase	Homo sapiens	5-8
7004733-8	1980	The relationship between renin and total body potassium was no longer present when the effects of age were allowed for in a partial correlation.	Potassium	46-55	renin	Homo sapiens	25-30
6254378-0	1980	Potassium ion as a regulator of adrenal angiotensin II receptors.	Potassium	0-9	angiotensinogen	Rattus norvegicus	40-54
7004733-4	1980	Total body potassium correlated with renin activity in both hypertensive patients and controls.	Potassium	11-20	renin	Homo sapiens	37-42
6254378-1	1980	The importance of potassium as a regulator of angiotensin II receptors of two target tissues has been investigated by combining high-K+ diet in rats with a converting enzyme inhibitor (Captopril; SQ 14,225) or angiotensin II.	Potassium	18-27	angiotensinogen	Rattus norvegicus	46-60
16592871-1	1980	Between dipolar aprotic solvents S(1) and S(2), the transfer activity coefficients, (S(1) )gamma(S(2) ), of complexed sodium, potassium, thallium(I), and silver ions with cryptand 2.2.2 have been found to be equal to that of the cryptand.	Potassium	126-135	proteasome 26S subunit, non-ATPase 1	Homo sapiens	84-89
6256174-7	1980	These results show that there was a relation between the levels of blood glucose and serum potassium after an insulin-containing hexose infusion and that membrane permeability was stereospecific.	Potassium	91-100	insulin	Canis lupus familiaris	110-117
6253559-1	1980	The ultrastructural cytochemical localization of a potassium-dependent oubain-sensitive nitrophenyl phosphatase (transport ATPase) activity in human blood platelets is described.	Potassium	51-60	dynein axonemal heavy chain 8	Homo sapiens	123-129
6903427-8	1980	In the rat vasopressin-induced changes in kallikrein excretion were positively correlated with changes in sodium and potassium excretion and negatively correlated with changes in free water clearance.	Potassium	117-126	arginine vasopressin	Rattus norvegicus	11-22
6997645-1	1980	The purpose of this study was to investigate whether pyruvate (2.5 mmol/kg), the combination of glucose (3.9 mmol/kg) and insulin (0.13 unit/kg) with potassium (9.27 meq/kg), or sodium dichloroacetate (120 mg/kg) infused for 15 minutes before and 20 minutes after ligation of the left anterior descending coronary arterv in anesthetized dogs restricted the depression in mitochondrial respiratory function induced by ischemia.	Potassium	150-159	insulin	Canis lupus familiaris	122-129
6776308-3	1980	The body cell mass represented by the exchangeable potassium to total body water ratio correlated significantly (p &lt; 0.001) with the serum albumin concentration (r = 0.59) and significantly (p &lt; 0.001) to total protein (r = 0.59).	Potassium	51-60	albumin	Homo sapiens	136-149
16592871-1	1980	Between dipolar aprotic solvents S(1) and S(2), the transfer activity coefficients, (S(1) )gamma(S(2) ), of complexed sodium, potassium, thallium(I), and silver ions with cryptand 2.2.2 have been found to be equal to that of the cryptand.	Potassium	126-135	ribosomal protein S2	Homo sapiens	91-101
7456395-0	1980	[Role of calcium and potassium in regulating prolactin and somatotropic hormone release in cell cultures of rat adenohypophysis].	Potassium	21-30	prolactin	Rattus norvegicus	45-54
6999040-2	1980	After change of cows from grass-clover hay to fescue-bluegrass pasture containing 22 to 31 g potassium/kg dry matter, immunoreactive insulin of 5 Holstein cows increased 30% in 5 days and averaged 45% above prepasture concentrations for 40 days.	Potassium	93-102	insulin	Bos taurus	133-140
6999040-8	1980	Injection of two Holstein cows with insulin (2 IU/kg body weight) reduced plasma concentrations of both potassium and magnesium 20% below that of two cows injected with only physiological saline.	Potassium	104-113	insulin	Bos taurus	36-43
7403676-1	1980	The vasodilator cinepazet (Vascoril) was tested for its ability to relax potassium-contracted aortic strips obtained from normal and spontaneously hypertensive rats (SHR).	Potassium	73-82	neurogenin 3	Rattus norvegicus	67-72
7456395-4	1980	Potassium (30 or 55 mM) stimulated PRL and GH release.	Potassium	0-9	prolactin	Rattus norvegicus	35-38
7456395-7	1980	In the absence of bicarbonate anions basal PRL and GH secretion was decreased, but calcium-dependent effect of high potassium level (55 mM) on PRL release persisted.	Potassium	116-125	prolactin	Rattus norvegicus	143-146
6990795-0	1980	Role of the renin-angiotensin system in potassium control.	Potassium	40-49	renin	Canis lupus familiaris	12-17
6247216-5	1980	Prolactin seems able to cause a prolonged reduction in water, sodium, and potassium excretion, a pattern that is imitated by no other hormone with the possible exception of growth hormone.	Potassium	74-83	prolactin	Homo sapiens	0-9
6247218-5	1980	Subsequent actions of prolactin may involve the following: a) an increased intracellular concentration of potassium and a reduced level of sodium, b) an increased level of cGMP and a reduced level of cAMP, c) an enhanced rate of prostaglandin biosyntheesis mediated by a stimulation of phospholipase A2 activity, and d) a stimulation of polyamine synthesis.	Potassium	106-115	prolactin	Homo sapiens	22-31
6990783-0	1980	Effect of graded doses of insulin on splanchnic and peripheral potassium metabolism in man.	Potassium	63-72	insulin	Homo sapiens	26-33
6990795-9	1980	The results demonstrate the importance of the renin-angiotensin system as a link between the nephron and the zona glomerulosa that is essential in controlling plasma potassium concentration and excretion during changes in sodium balance.	Potassium	166-175	renin	Canis lupus familiaris	46-51
7000466-8	1980	In the hypertensives correlations were found between 24 hour kallikrein excretion and potassium excretion (r=0.51; p &lt; 0.05), aldosterone excretion (r=0.57; p &lt; 0.01), and creatinine clearance (r=0.59; p &lt; 0.01).	Potassium	86-95	kallikrein related peptidase 4	Homo sapiens	61-71
7000394-0	1980	Renin and aldosterone in hypothyroidism: relation to excretion of sodium and potassium.	Potassium	77-86	renin	Homo sapiens	0-5
7378487-5	1980	It was suggested that opiates cause a formation of the potassium carrier in mitochondria by releasing Ca2+, which activate phospholipase A2.	Potassium	55-64	phospholipase A2 group IB	Rattus norvegicus	123-139
7352016-4	1980	A direct measurement of reversal potential in normal ionic conditions was not achieved but it was suggested that substance P acts by reducing membrane potassium conductance.	Potassium	151-160	tachykinin precursor 1	Homo sapiens	113-124
7352016-5	1980	In contrast, work on salivary glands suggests that substance P evokes an increase in potassium conductance; however,electrophysiological work has not been carried out to verify this.	Potassium	85-94	tachykinin precursor 1	Homo sapiens	51-62
6989888-5	1980	LHRH stimulation by PGE2 (pulse) proceeds in the absence of external calcium, and the effect lasts longer than the potassium (pulse) action.	Potassium	115-124	gonadotropin releasing hormone 1	Rattus norvegicus	0-4
6770336-3	1980	Insulin secretion in response to glucose, potassium and tolbutamide was lower in a Sr2+ than in a Ca2+ medium, even at the optimum concentration of 2.5 mmol/l.	Potassium	42-51	insulin	Homo sapiens	0-7
6770336-3	1980	Insulin secretion in response to glucose, potassium and tolbutamide was lower in a Sr2+ than in a Ca2+ medium, even at the optimum concentration of 2.5 mmol/l.	Potassium	42-51	Stress response QTL 2	Rattus norvegicus	83-86
6244905-3	1980	Helical strips of rat tail artery relax in response to potassium after norepinephrine-induced contractions in physiological salt solution containing a low-potassium concentration.	Potassium	55-64	relaxin 1	Rattus norvegicus	34-39
6244905-3	1980	Helical strips of rat tail artery relax in response to potassium after norepinephrine-induced contractions in physiological salt solution containing a low-potassium concentration.	Potassium	155-164	relaxin 1	Rattus norvegicus	34-39
6767908-6	1980	The patients of the low dose insulin infusion regimen needed less insulin, potassium and bicarbonate and reached earlier a bloodglucose level of 300 mg/dl.	Potassium	75-84	insulin	Homo sapiens	29-36
6991669-0	1980	Separate and combined effects of ouabain and extracellular potassium on renin secretion from rat renal cortical slices.	Potassium	59-68	renin	Rattus norvegicus	72-77
6987815-2	1980	Multiple factors, including the level of renal function, acid base status, activity of the renin-angiotension-aldosterone system, and the availability of insulin, normally interact to control the serum potassium concentration.	Potassium	202-211	renin	Homo sapiens	91-96
6987815-2	1980	Multiple factors, including the level of renal function, acid base status, activity of the renin-angiotension-aldosterone system, and the availability of insulin, normally interact to control the serum potassium concentration.	Potassium	202-211	insulin	Homo sapiens	154-161
6930755-3	1980	Parenteral substitution of potassium resulted in complete normalisation of the clinical signs and of the pathologically elevated serum concentrations of CPK, LDH and GOT.	Potassium	27-36	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	153-156
6997221-9	1980	Renin-aldosterone system during diuretic therapy not only causes the so-called false tolerance to antihypertensive effect, but also potentiates the loss of potassium.	Potassium	156-165	renin	Homo sapiens	0-5
7374953-0	1980	Facilitation by "low sodium-urea" medium of the washout of dopamine beta-hydroxylase released by potassium ions from the perfused rabbit heart.	Potassium	97-106	dopamine beta-hydroxylase	Oryctolagus cuniculus	59-84
399571-0	1980	An association between the renin angiotensin system, blood pressure and potassium intake.	Potassium	72-81	renin	Homo sapiens	27-32
7443728-5	1980	Raising the concentration of potassium ions stimulated the release of met- and leu-enkephalin from striatal slices and the release of beta-endorphin immunoreactive material(s) from hypothalamic slices; both phenomena were dependent upon the presence of calcium ions.	Potassium	29-38	proenkephalin	Rattus norvegicus	83-93
7443728-5	1980	Raising the concentration of potassium ions stimulated the release of met- and leu-enkephalin from striatal slices and the release of beta-endorphin immunoreactive material(s) from hypothalamic slices; both phenomena were dependent upon the presence of calcium ions.	Potassium	29-38	proopiomelanocortin	Homo sapiens	134-148
514084-9	1979	Plasma Na+, Ca++ and osmolality were not significantly altered by the diet in either SH or WKY rats; plasma potassium was significantly lower in the SH group fed the hCa diet than in the group given rCa.	Potassium	108-117	HCA1	Homo sapiens	166-169
396384-5	1979	In the present study, it was suggested that the secondary hyperaldosteronism following low cardiac output syndrome after open cardiac surgery was mainly induced by the increased release of renin and that it influenced on the balance of sodium and potassium metabolism under such disturbed circulatory circumstances.	Potassium	247-256	renin	Homo sapiens	189-194
93729-3	1979	Potassium (50 mM) locally applied stimulated SP release in both structures.	Potassium	0-9	tachykinin precursor 1	Homo sapiens	45-47
93729-4	1979	Furthermore an important evoked release of SP was observed in the SN during depolarization of striato-nigral SP fibers with potassium (50 mM) applied in the CN.	Potassium	124-133	tachykinin precursor 1	Homo sapiens	43-45
43583-1	1979	The effect of potassium on somatostatin secretion from the isolated perfused canine pancreas was studied.	Potassium	14-23	somatostatin	Canis lupus familiaris	27-39
93729-4	1979	Furthermore an important evoked release of SP was observed in the SN during depolarization of striato-nigral SP fibers with potassium (50 mM) applied in the CN.	Potassium	124-133	tachykinin precursor 1	Homo sapiens	109-111
515720-6	1979	However, in the non-ketotic patients low-dose insulin therapy resulted in a delayed fall in blood glucose and distinctly diminished potassium retention.	Potassium	132-141	insulin	Homo sapiens	46-53
43583-2	1979	Potassium stimulated dose-dependent somatostatin release in a monophasic response pattern.	Potassium	0-9	somatostatin	Canis lupus familiaris	36-48
43583-5	1979	The results suggest that the stimulatory effect of potassium on somatostatin release is secondary to increases in calcium influx into the D cell.	Potassium	51-60	somatostatin	Canis lupus familiaris	64-76
43394-0	1979	Recovery of pHi in snail neurones exposed to high external potassium [proceedings].	Potassium	59-68	glucose-6-phosphate isomerase	Homo sapiens	12-15
519911-2	1979	The enhanced renal response to aldosterone observed in rats on a high potassium diet is reduced by the administration of either haloperidol, a dopamine receptor blocker, or carbidopa, a peripheral blocker of dopa decarboxylase.	Potassium	70-79	dopa decarboxylase	Rattus norvegicus	208-226
158981-4	1979	The adenosine triphosphatase (ATPase) of the myosin is activated by potassium and calcium and it is inhibited by magnesium.	Potassium	68-77	myosin heavy chain 14	Homo sapiens	45-51
395185-1	1979	A paradoxical transitory elevation of serum potassium concentration after intravenous infusion of hypertonic glucose has been found in 6 renal and/or hypertensive patients with suppression of the renin-aldosterone system (RAS) while on high sodium intake.	Potassium	44-53	renin	Homo sapiens	196-201
510363-0	1979	Enhancement by elevated external potassium of the maximal responses to acetylcholine and norepinephrine in the rat vas deferens.	Potassium	33-42	arginine vasopressin	Rattus norvegicus	115-118
510363-1	1979	In the rat vas deferens, the maximal response to acetylcholine increased almost linearly as a function of external potassium concentration, [K+]0.	Potassium	115-124	arginine vasopressin	Rattus norvegicus	11-14
315865-1	1979	The effect of synthetic melanocyte-stimulating hormones (MSH) on urinary excretion of sodiu, potassium and water was studied in hamsters.	Potassium	93-102	proopiomelanocortin	Homo sapiens	57-60
315865-7	1979	Changes in urinary excretion of sodium and potassium are considered to be consequence of direct renal action of MSH.	Potassium	43-52	proopiomelanocortin	Homo sapiens	112-115
500584-4	1979	During the first 48 h after the injection of Triton WR-1339, the rate of catalase synthesis (ks) fell to below a detectable value, while that of the degradation (kd) did not show any significant change.	Potassium	93-95	catalase	Rattus norvegicus	73-81
495117-6	1979	In preparations of pregnant human myometrium, normally polarized or potassium depolarized, oxytocin induced a contractile activity that was effectively inhibited by nifedipine.	Potassium	68-77	oxytocin/neurophysin I prepropeptide	Homo sapiens	91-99
94410-6	1979	The intravenous administration of 80 units crystalline zinc insulin produced both hypokalemia (3.78 +/- 0.22 reduced to 2.36 +/- 0.18 mEq potassium/liter plasma) and a reappearance of ventricular tachycardia despite no change in plasma and myocardial tissue concentrations of disopyramide from those which had been effective in establishing and maintaining sinus rhythm.	Potassium	138-147	insulin	Canis lupus familiaris	60-67
226679-0	1979	Are acetylcholine-induced increases in potassium efflux mediated by intracellular cyclic GMP in cardiac pacemaker tissue?	Potassium	39-48	5'-nucleotidase, cytosolic II	Homo sapiens	89-92
445707-6	1979	Under these conditions, A II produces a small initial hyperpolarization, which is modified by external potassium concentration changes and abolished by tetraethylammonium chloride.	Potassium	103-112	angiotensinogen	Rattus norvegicus	24-28
467498-1	1979	The rate of release of beta-endorphin-like immunoreactivity (beta-EI) from rat hypothalamic slices was increased 3- to 4-fold over the spontaneous release during exposure to a depolarizing concentration of potassium ions.	Potassium	206-215	proopiomelanocortin	Homo sapiens	23-37
493200-0	1979	Birmingham Medical Research Expeditionary Society 1977 Expedition: effect of a Himalayan trek on whole body composition, nitrogen and potassium.	Potassium	134-143	potassium two pore domain channel subfamily K member 2	Homo sapiens	89-93
459246-6	1979	In a juvenile-onset diabetic subject, the impairment of cellular potassium uptake at higher plasma potassium was magnified so that infused potassium was virtually confined to the ECF compartment until exogenous insulin was given.	Potassium	65-74	insulin	Homo sapiens	211-218
459246-7	1979	This implies a permissive rather than a regulatory role for endogenous insulin in facilitating cellular entry of excess potassium.	Potassium	120-129	insulin	Homo sapiens	71-78
454584-0	1979	Effect of the sodium/potassium ratio on glyceraldehyde 3-phosphate dehydrogenase interaction with red cell vesicles.	Potassium	21-30	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	40-80
490364-0	1979	Influence of potassium, sodium, perfusion pressure, and isoprenaline on renin release induced by acute calcium deprivation.	Potassium	13-22	renin	Rattus norvegicus	72-77
508208-0	1979	Plasma insulin concentrations during infusions of potassium and sodium chloride solutions into conscious splenectomized sheep.	Potassium	50-59	LOC105613195	Ovis aries	7-14
508208-4	1979	It was concluded that this increase in insulin concentration was caused by elevation of the plasma potassium concentration and was not due to coincident increases in plasma chloride concentration or osmolality.	Potassium	99-108	LOC105613195	Ovis aries	39-46
454584-6	1979	Alteration of the potassium concentration at the extracellular face of the vesicle affects the conformation of glyceraldehyde-3-phosphate dehydrogenase at the cytoplasmic face, thus showing that a conformation changed induced by a change in extracellular potassium can be transmitted across the membrane.	Potassium	18-27	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	111-151
467498-4	1979	70% of the potassium-induced released immunoreactive material migrated on a calibrated Sephadex G-50 column like synthetic human beta-endorphin.	Potassium	11-20	proopiomelanocortin	Homo sapiens	129-143
454584-6	1979	Alteration of the potassium concentration at the extracellular face of the vesicle affects the conformation of glyceraldehyde-3-phosphate dehydrogenase at the cytoplasmic face, thus showing that a conformation changed induced by a change in extracellular potassium can be transmitted across the membrane.	Potassium	255-264	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	111-151
454584-12	1979	The sodium/potassium concentration dependence of this process in red cells is mimicked by 31P resonance shifts in the (glyceraldehyde 3-phosphate/glyceraldehyde-3-phosphate dehydrogenase/inside out vesicle) system.	Potassium	11-20	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	146-186
219653-5	1979	A 24-h angiotensin II infusion into sodium- and potassium-replete rats induced significant increases in both the serum aldosterone and the conversion.	Potassium	48-57	angiotensinogen	Rattus norvegicus	7-21
35288-0	1979	Evaluation of an instrument (Nova-1) for direct potentiometric analysis of sodium and potassium in blood and their indirect potentiometric determination in urine.	Potassium	86-95	NOVA alternative splicing regulator 1	Homo sapiens	29-35
217869-5	1979	Moreover, potassium (100 mM) decreases the binding of beta-endorphin but does not affect enkephalin binding.	Potassium	10-19	proopiomelanocortin	Homo sapiens	54-68
439071-4	1979	In immature rats this effect of hCG was dose-dependent and time-related and the accumulated fluid contained high levels of potassium and phosphate; levels of sodium, calcium and protein were similar to those in serum.	Potassium	123-132	hypertrichosis 2 (generalised, congenital)	Homo sapiens	32-35
33823-3	1979	Parenchymal hexokinase is more susceptible to glucose inhibition, can tolerate greater variations in the ATP concentration, is inhibited by increasing concentrations of fructose and potassium, and showed greater activity on the lower pH values.	Potassium	182-191	hexokinase 1	Homo sapiens	12-22
474181-3	1979	AII was then correlated statistically to PRA, PA and 24-hour urinary excretions of aldosterone (Aldo-U), sodium and potassium and to the blood pressure (BP) levels.	Potassium	116-125	angiotensinogen	Homo sapiens	0-3
744810-3	1978	Milk from cows with evidence of udder infection had higher sodium and chloride and lower potassium than cows free of mastitis.	Potassium	89-98	Weaning weight-maternal milk	Bos taurus	0-4
454855-0	1979	The role of sodium and potassium ions in the contractile response and development of tachyphylaxis to angiotensin II on vascular smooth muscle.	Potassium	23-32	angiotensinogen	Rattus norvegicus	102-116
429482-4	1979	hGH-S was more potent than hGH-I, as measured by nitrogen and potassium retention, and the differences reached levels of statistical significance.	Potassium	62-71	GHS	Homo sapiens	0-5
429482-7	1979	We conclude hGH-S, a two-chain form of hGH, caused significantly greater nitrogen and potassium retention in human subjects in short term balance studies than hGH-I.	Potassium	86-95	GHS	Homo sapiens	12-17
217942-5	1978	Glands made refractory to LH-RH showed a decreased response to potassium and, conversely, the release of LH in response to LH-RH was reduced after exposure of glands to potassium.	Potassium	63-72	gonadotropin releasing hormone 1	Rattus norvegicus	26-31
217942-5	1978	Glands made refractory to LH-RH showed a decreased response to potassium and, conversely, the release of LH in response to LH-RH was reduced after exposure of glands to potassium.	Potassium	169-178	gonadotropin releasing hormone 1	Rattus norvegicus	123-128
31212-0	1978	[Allosteric modification of adenylate deaminase activity: appearance of adenosine deaminase activity as an effect of potassium ions].	Potassium	117-126	adenosine deaminase	Homo sapiens	72-91
217942-6	1978	It is concluded that the LH releasing activity of LH-RH, which is mimicked by potassium, deteriorates during continuous exposure to the secretagogue.	Potassium	78-87	gonadotropin releasing hormone 1	Rattus norvegicus	50-55
366104-0	1978	Does calcium mediate the increase in potassium permeability due to phenylephrine or angiotensin II in the liver?	Potassium	37-46	angiotensinogen	Homo sapiens	84-98
718976-2	1978	A new hydrodynamic treatment has been used to calculate the molecular weight of myosin from s0 and ks alone and has yielded a value of 470 000.	Potassium	99-101	myosin heavy chain 14	Homo sapiens	80-86
31212-2	1978	Adenosine deaminase activity originates at the concentration of K+ of 0.15 M that possesses the most stimulating effect on adenylate deaminase activity; with the increase of potassium ions concentration adenosine deaminating activity is enhanced as well, with a parallel reduction of Hill"s constant.	Potassium	174-183	adenosine deaminase	Homo sapiens	0-19
263797-0	1978	Effects of dietary potassium and race on urinary excretion of kallikrein and aldosterone in man.	Potassium	19-28	kallikrein related peptidase 4	Homo sapiens	62-72
719960-12	1978	Pronounced rises in plasma insulin immunoreactivities during salbutamol infusions suggested this as one mechanism for potassium shifts.	Potassium	118-127	insulin	Canis lupus familiaris	27-34
30034-6	1978	The result revealed a far-reaching potassium neutrality of diuresis-depending stimulation of renin by the beta-receptor blocker.	Potassium	35-44	renin	Homo sapiens	93-98
682988-0	1978	Somatostatin secretion from the rat neurohypophysis and stalk median eminence (SME) in vitro: calcium-dependent release by high potassium and electrical stimulation.	Potassium	128-137	somatostatin	Rattus norvegicus	0-12
687606-6	1978	Only that deuteroporphyrin taken up in parallel to the transmembrane potassium gradient is accessible to ferrochelatase.	Potassium	69-78	ferrochelatase	Rattus norvegicus	105-119
712625-0	1978	The effects of ouabain and alterations in potassium concentration on the sensitivity to drugs and the membrane potential of the smooth muscle of the guinea-pig and rat vas deferens.	Potassium	42-51	arginine vasopressin	Rattus norvegicus	168-171
695748-5	1978	Phenobarbitone when administered alone increased serum minerals except sodium, but to a lesser degree than CCl4, while phenobarbitone when given repeatedly together with small doses of CCl4 led to a normalization of serum iron, calcium and potassium.	Potassium	240-249	C-C motif chemokine ligand 4	Homo sapiens	185-189
263797-2	1978	Excretion of kallikrein varied directly with potassium intake and paralleled excretion of aldosterone in both normotensive and hypertensive subjects.	Potassium	45-54	kallikrein related peptidase 4	Homo sapiens	13-23
263797-3	1978	Mean levels of excretion of kallikrein at 85, 185, and 25 meq intake of potassium were 10.8, 19.1, and 5.8 esterase U/day (EU/day), respectively, for the normotensive subjects and 8.8, 13.9, and 6.1 EU/day for the hypertensive subjects.	Potassium	72-81	kallikrein related peptidase 4	Homo sapiens	28-38
105888-3	1978	Membrane depolarization produced by increasing the medium potassium concentration to 60 mM increased GnRH release to 200-500% of control.	Potassium	58-67	gonadotropin releasing hormone 1	Rattus norvegicus	101-105
695695-10	1978	It is concluded that the Km is determined not only by the Ks of type I binding and the reduction rate of the type I complex between ethylmorphine and cytochrome P-450.	Potassium	58-60	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	150-166
744066-4	1978	In glomerulosa cells, ACTH produced the greatest 18-OH-DOC response but A-II and potassium also produced significant (P less than 0.001) 18-OH-DOC increases (control, 162 +/- 14 (SE) ng/10(6) cells incubated; A-II, 368 +/- 39; potassium, 380 +/- 37; ACTH, 1544 +/- 165).	Potassium	81-90	angiotensinogen	Rattus norvegicus	209-213
744066-4	1978	In glomerulosa cells, ACTH produced the greatest 18-OH-DOC response but A-II and potassium also produced significant (P less than 0.001) 18-OH-DOC increases (control, 162 +/- 14 (SE) ng/10(6) cells incubated; A-II, 368 +/- 39; potassium, 380 +/- 37; ACTH, 1544 +/- 165).	Potassium	227-236	angiotensinogen	Rattus norvegicus	72-76
105888-7	1978	Both no calcium-EDTA medium and verapamil (10(-5) M) prevented the stimulation of GnRH release by 60 mM potassium, 10(-3) M melatonin, and 4 X 10(-4) M prostaglandin E2.	Potassium	104-113	gonadotropin releasing hormone 1	Rattus norvegicus	82-86
206480-0	1978	Epinephrine enhancement of potassium-stimulated immunoreactive insulin secretion.	Potassium	27-36	insulin	Canis lupus familiaris	63-70
565782-12	1978	Addition of potassium and magnesium to the cytoplasm, to concentrations that would polymerize muscle actin, does not increase the amount of sedimentable actin.	Potassium	12-21	actin like 6A S homeolog	Xenopus laevis	101-106
630399-0	1978	Vasoactive intestinal polypeptide (VIP): vesicular localization and potassium evoked release from rat hypothalamus.	Potassium	68-77	vasoactive intestinal peptide	Rattus norvegicus	0-33
639850-1	1978	The rate of release of enkephalin from rat striatal slices increased 7--10 fold in response to depolarization by 50 mM potassium ions in vitro.	Potassium	119-128	proenkephalin	Rattus norvegicus	23-33
681448-0	1978	Protection of the ischaemic myocardium by glucose-insulin-potassium infusion assessed by ventricular function and electron microscopy.	Potassium	58-67	insulin	Homo sapiens	50-57
647213-6	1978	In all experiments there was a direct relation between a fall in serum potassium concentration and the fall in plasma glucose concentration irrespective of the mechanism that reduced the glucose concentration.These results indicate that in uncontrolled diabetics low-dose insulin infusions lower the blood glucose concentration entirely by reducing glucose production from the liver and that the effect of insulin on potassium transport is independent of its effect on glucose uptake.	Potassium	71-80	insulin	Homo sapiens	272-279
647213-6	1978	In all experiments there was a direct relation between a fall in serum potassium concentration and the fall in plasma glucose concentration irrespective of the mechanism that reduced the glucose concentration.These results indicate that in uncontrolled diabetics low-dose insulin infusions lower the blood glucose concentration entirely by reducing glucose production from the liver and that the effect of insulin on potassium transport is independent of its effect on glucose uptake.	Potassium	71-80	insulin	Homo sapiens	406-413
647213-6	1978	In all experiments there was a direct relation between a fall in serum potassium concentration and the fall in plasma glucose concentration irrespective of the mechanism that reduced the glucose concentration.These results indicate that in uncontrolled diabetics low-dose insulin infusions lower the blood glucose concentration entirely by reducing glucose production from the liver and that the effect of insulin on potassium transport is independent of its effect on glucose uptake.	Potassium	417-426	insulin	Homo sapiens	272-279
672000-2	1978	The dependence of renin activity and potassium content is analysed.	Potassium	37-46	renin	Homo sapiens	18-23
672000-4	1978	It is presumed that changes in potassium metabolism play an important role in the changes in renin activity in myocardial infarction.	Potassium	31-40	renin	Homo sapiens	93-98
638887-0	1978	Effect of the external concentrations of potassium and sodium on the release of (--)-[3H]noradrenaline from the adrenergic nerves of the rat vas deferens.	Potassium	41-50	arginine vasopressin	Rattus norvegicus	141-144
688983-1	1978	In a hyperkalemic patient with stable chronic renal failure and suppression of the renin-angiotensin-aldosterone system intravenous infusion of hypertonic glucose induced a paradoxical transitory rise in serum potassium accompanied by a similar change in plasma aldosterone.	Potassium	210-219	renin	Homo sapiens	83-88
688983-2	1978	The close significant correlation indicated a prominent role for serum potassium in the acute regulation of plasma aldosterone when the renin-angiotensin-aldosterone system was suppressed.	Potassium	71-80	renin	Homo sapiens	136-141
688983-3	1978	However, when the renin-angiotensin-aldosterone system was stimulated by sodium depletion the glucose-induced paradoxical hyperkalemia was abolished and the governing role of potassium became less evident.	Potassium	175-184	renin	Homo sapiens	18-23
635985-2	1978	Sa I A/4 (H-2a, i.e., H-2k/d) was enhanced in CBA (H-2k) and C57BL/Ks (H-2d) strains with anti-A/J immune sera prepared in CBA and C57BL/Ks, respectively.	Potassium	67-69	histocompatibility 2, K1, K region	Mus musculus	22-28
635985-2	1978	Sa I A/4 (H-2a, i.e., H-2k/d) was enhanced in CBA (H-2k) and C57BL/Ks (H-2d) strains with anti-A/J immune sera prepared in CBA and C57BL/Ks, respectively.	Potassium	67-69	histocompatibility 2, D region	Mus musculus	71-75
206380-0	1978	[Self-association of 5"-GMP: nucelation by potassium ions].	Potassium	43-52	5'-nucleotidase, cytosolic II	Homo sapiens	24-27
206380-2	1978	For a 0,1 M concentration in 5"-GMP, large aggregates are formed only in presence of the potassium ion, at greater than 0.2 M concentrations.	Potassium	89-98	5'-nucleotidase, cytosolic II	Homo sapiens	32-35
206380-4	1978	A plausible explantation is inclusion of the cation in the central cavity of 5"-GMP tetramers, with a marked selectivity in favor of potassium.	Potassium	133-142	5'-nucleotidase, cytosolic II	Homo sapiens	80-83
670540-4	1978	Plasma renin activity also was low, and was hyporesponsive to stimulation, including intravascular volume contraction and potassium depletion.	Potassium	122-131	renin	Homo sapiens	7-12
623299-3	1978	Potassium was retained for 7 days until escape of vasopressin-induced potassium retention occurred.	Potassium	0-9	arginine vasopressin	Rattus norvegicus	50-61
623299-3	1978	Potassium was retained for 7 days until escape of vasopressin-induced potassium retention occurred.	Potassium	70-79	arginine vasopressin	Rattus norvegicus	50-61
621284-4	1978	A similar rise in serum potassium was observed in normal conscious dogs given somatostatin and was reversed by insulin replacement.	Potassium	24-33	insulin	Canis lupus familiaris	111-118
620577-3	1978	In four patients the glucose-insulin-potassium solution was instilled directly into the right pulmonary artery from the tip of the Swan-Ganz catheter.	Potassium	37-46	insulin	Homo sapiens	29-36
750607-1	1978	Previous studies from this laboratory have demonstrated that the redistribution of blood volume and concomitant central hypervolemia induced by water immersion to the neck (NI), produces a prompt and profound suppression of plasma renin activity (PRA) and plasma aldosterone concentration (PA) without concomitant alterations in serum sodium and potassium concentrations.	Potassium	346-355	renin	Homo sapiens	231-236
206750-5	1978	Met- and leu-enkephalin (10(-7)-10(-5) M) decreased the high potassium induced [3H]-norepinephrine release from vas deferens, while substance P (10(-6) M) significantly increased it.	Potassium	61-70	prodynorphin	Mus musculus	9-23
635218-5	1978	These results make unlikely the hypothesis that the polyuria of potassium-deficiency, is the result of enhanced renal synthesis of prostaglandins with subsequent antagonism of the hydro-osmotic effect of vasopressin.	Potassium	64-73	arginine vasopressin	Rattus norvegicus	204-215
624102-1	1978	Total cerebral ischaemia in rats caused a marked increase in the cisternal CSF potassium concentration but little change in CSF sodium or chloride concentration.	Potassium	79-88	colony stimulating factor 2	Rattus norvegicus	75-78
667411-3	1978	Upon increasing the external potassium concentration a significant rise in somatostatin release from both tissues was observed.	Potassium	29-38	somatostatin	Rattus norvegicus	75-87
696414-9	1978	Overactivity of the renin-angiotensin-aldosterone system during this regime might explain both the lack of a beneficial effect on BP and the adverse influence on serum potassium.	Potassium	168-177	renin	Homo sapiens	20-25
147117-1	1978	Helical strips of rat tail artery were observed to relax in response to potassium after contraction induced by 10(-7) g/ml norepinephrine in potassium-free solution.	Potassium	72-81	neurogenin 3	Rattus norvegicus	51-56
621284-7	1978	Addition of replacement doses of insulin to the somatostatin infusion resulted in increments in serum potassium which were comparable to infusion of KCl alone.	Potassium	102-111	insulin	Canis lupus familiaris	33-40
621284-11	1978	It is concluded that (a) potassium homeostasis is influenced by basal insulin levels in the absence of which serum potassium concentration rises and potassium tolerance declines; (b) this effect of insulin is mediated via extrarenal mechanisms of potassium disposal; (c) somatostatin has a biphasic effect on urinary sodium secretion, the mechanism of which remains to be established.	Potassium	25-34	insulin	Canis lupus familiaris	70-77
143960-8	1977	Ouabain-resistant (Na,K)ATPase of HI-C1 has an apparent K0.5 for potassium 3-4 times higher than that of either wild type enzyme or the resistant enzyme of HI-B1.	Potassium	65-74	HIC ZBTB transcriptional repressor 1	Homo sapiens	34-39
590636-7	1977	These results, which give no evidence of a direct effect of insulin on electrolyte transport in brain, are in sharp contrast with those found in anesthetized rabbits, which suggested that insulin affects brain potassium and water content before any change in plasma glucose occurs.	Potassium	210-219	insulin	Oryctolagus cuniculus	188-195
908483-3	1977	The duct cells responded to increasing doses of secretin by producing more juice with increasing outputs of bicarbonate, sodium, potassium, and chloride.	Potassium	129-138	secretin	Rattus norvegicus	48-56
145813-4	1977	Potassium stimulates insulin and aldosterone secretion and increases Na-K ATPase in the distal nephron, so promoting its own redistribution or excretion.	Potassium	0-9	insulin	Homo sapiens	21-28
908483-5	1977	The concentration of potassium increased with increasing doses of secretin and flow rates, whereas chloride concentration decreased in a reciprocal fashion to bicarbonate.	Potassium	21-30	secretin	Rattus norvegicus	66-74
198193-0	1977	Interaction of somatostatin inhibition and dibutyryl cyclic AMP or potassium stimulation of growth hormone release from perifused rat pituitaries.	Potassium	67-76	gonadotropin releasing hormone receptor	Rattus norvegicus	92-106
413096-0	1977	Cardiac Purkinje fibres: [Ca2+]i controls the potassium permeability via the conductance components gK1 and gK2.	Potassium	46-55	glycerol kinase 2	Ovis aries	108-111
918352-2	1977	The abnormal serum potassium response developed in spite of a normal insulin release and was abolished by pharmacological doses of mineralocorticoids in two.	Potassium	19-28	insulin	Homo sapiens	69-76
927556-0	1977	Influence of changed calcium and potassium concentration on the algesic effect of bradykinin and acetylcholine.	Potassium	33-42	kininogen 1	Homo sapiens	82-92
910910-8	1977	These results indicate that increased renal choline phosphoglyceride formation during potassium depletion can occur via the Kennedy pathway and appears to be mediated by increases in choline uptake and the rate of CDP-choline incorporation into phospholipid, the first and last steps of the pathway.	Potassium	86-95	cut-like homeobox 1	Rattus norvegicus	214-217
886216-1	1977	Previous studies have suggested that large intakes of potassium (K) will suppress plasma renin activity (PRA) in normal man.	Potassium	54-63	renin	Homo sapiens	89-94
913046-0	1977	Potentiation of pressor effects of noradrenaline and potassium ions in the rat mesenteric arteries by physiological concentrations of angiotensin II: effects of prostaglandin E2 and cortisol.	Potassium	53-62	angiotensinogen	Rattus norvegicus	134-148
909611-2	1977	In rat brain slices preincubated with various radiolabelled putative neurotransmitters, methionine-enkephalin diminished the potassium-evoked release of dopamine and acetylcholine.	Potassium	125-134	proenkephalin	Rattus norvegicus	99-109
910910-3	1977	Cortical and medullary tissue from potassium-depleted and control animals accumulated extracellular choline and sequentially converted it to phosphorylcholine, cytidine diphosphocholine (CDP-choline), and choline phosphoglyceride, thereby demonstrating that renal cells can utilize the Kennedy pathway for phospholipid synthesis.	Potassium	35-44	cut-like homeobox 1	Rattus norvegicus	187-190
142633-3	1977	Previous reports of activation of the NaK ATPase at low potassium and high sodium are probably not due to phenytoin but to a potassium contamination in the phenytoin solution.	Potassium	56-65	dynein axonemal heavy chain 8	Homo sapiens	42-48
142633-3	1977	Previous reports of activation of the NaK ATPase at low potassium and high sodium are probably not due to phenytoin but to a potassium contamination in the phenytoin solution.	Potassium	125-134	dynein axonemal heavy chain 8	Homo sapiens	42-48
837868-0	1977	Effect of acute potassium loading on plasma renin and on urinary aldosterone in rats.	Potassium	16-25	renin	Rattus norvegicus	44-49
560488-6	1977	Cardiac muscle cells stimulated at a rate of 150 min-1 in the presence of 5.4 mM external potassium were found to have a potassium efflux of 15.7 pmoles cm-2sec-1 whereas the value obtained for the fibroblastlike cells was 1.88 pmoles cm-2sec-1.	Potassium	90-99	secretory blood group 1, pseudogene	Homo sapiens	157-162
560488-6	1977	Cardiac muscle cells stimulated at a rate of 150 min-1 in the presence of 5.4 mM external potassium were found to have a potassium efflux of 15.7 pmoles cm-2sec-1 whereas the value obtained for the fibroblastlike cells was 1.88 pmoles cm-2sec-1.	Potassium	90-99	secretory blood group 1, pseudogene	Homo sapiens	239-244
560488-6	1977	Cardiac muscle cells stimulated at a rate of 150 min-1 in the presence of 5.4 mM external potassium were found to have a potassium efflux of 15.7 pmoles cm-2sec-1 whereas the value obtained for the fibroblastlike cells was 1.88 pmoles cm-2sec-1.	Potassium	121-130	secretory blood group 1, pseudogene	Homo sapiens	157-162
560488-6	1977	Cardiac muscle cells stimulated at a rate of 150 min-1 in the presence of 5.4 mM external potassium were found to have a potassium efflux of 15.7 pmoles cm-2sec-1 whereas the value obtained for the fibroblastlike cells was 1.88 pmoles cm-2sec-1.	Potassium	121-130	secretory blood group 1, pseudogene	Homo sapiens	239-244
870233-3	1977	In normal subjects, angiotensin II at 3 ng/kg per min or potassium at 20 mEq/hour infused intravenously for 2 hours both significantly increased plasma aldosterone levels, yet neither stimulus altered plasma bradykinin.	Potassium	57-66	kininogen 1	Homo sapiens	208-218
15586-7	1977	pH dependent k2 and KS values were used to calculate values for k1 and k-1, the binding and debinding rate constants for the two p-nitrophenyl compounds.	Potassium	20-22	keratin 1	Homo sapiens	64-74
558594-8	1977	Alteration in potassium driving force over time results in a time-dependent ik1 even though the underlying conductance is time-independent [29].	Potassium	14-23	IKAROS family zinc finger 1	Homo sapiens	76-79
843146-6	1977	It is possible that increased activity of the renin axis, triggered by excessive volume depletion and perhaps by changes in potassium balance, were responsible for sustaining the high levels of blood pressure in those patients failing to respond to treatment.	Potassium	124-133	renin	Homo sapiens	46-51
842485-6	1977	Total body potassium (40K determinations) agreed well with previous studies of older subjects.	Potassium	11-20	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	22-25
855379-4	1977	After treatment with insulin, most of these serum levels approached the normal, except for serum potassium and magnesium.	Potassium	97-106	insulin	Homo sapiens	21-28
842662-8	1977	The tissue potassium content was found to decline from 48.4 /- 10.1 meg/kg at the proximal site to 23.6 +/- 8.0 meg k/g at the distal site.	Potassium	11-20	protein tyrosine phosphatase non-receptor type 4	Homo sapiens	68-71
842662-8	1977	The tissue potassium content was found to decline from 48.4 /- 10.1 meg/kg at the proximal site to 23.6 +/- 8.0 meg k/g at the distal site.	Potassium	11-20	protein tyrosine phosphatase non-receptor type 4	Homo sapiens	112-115
14149-3	1977	Higher concentrations of potassium and magnesium ions were required for the translation of albumin mRNA than for total liver mRNAs.	Potassium	25-34	albumin	Rattus norvegicus	91-98
14149-5	1977	At the higher potassium or magnesium concentrations, only intact albumin molecules were synthesized, whereas lower concentrations of these ions caused the production of antibody-reactive fragments.	Potassium	14-23	albumin	Rattus norvegicus	65-72
190897-1	1977	It has been demonstrated previously that a high concentration of potassium in the serosal bathing medium (5-21.5 mM) potentiates the increase in short-circuit current caused by vasopressin or exogenous cyclic AMP.	Potassium	65-74	arginine vasopressin	Homo sapiens	177-188
188628-0	1977	Aldosterone production by isolated glomerulosa cells: modulation of sensitivity to angiotensin II and ACTH by extracellular potassium concentration.	Potassium	124-133	proopiomelanocortin	Canis lupus familiaris	102-106
188628-1	1977	The influence of extracellular potassium concentration on adrenal sensitivity to angiotensin II and ACTH was studied in isolated canine adrenal glomerulosa cells.	Potassium	31-40	proopiomelanocortin	Canis lupus familiaris	100-104
188628-2	1977	When potassium was absent from the incubation medium, the aldosterone response to angiotensin II or ACTH was completely abolished.	Potassium	5-14	proopiomelanocortin	Canis lupus familiaris	100-104
188628-5	1977	The effect of potassium concentration upon the aldosterone response to ACTH was similar but less marked.	Potassium	14-23	proopiomelanocortin	Canis lupus familiaris	71-75
612271-3	1977	Intracellular potassium depletion was associated with a slight impaired carbohydrate tolerance and with decreased growth hormone response to arginine infusion and insulin-induced hypoglycemia.	Potassium	14-23	growth hormone 1	Homo sapiens	114-128
30731547-11	1977	Literature data suggest the following changes in the milk composition from quarters definitely positive to mastitis screening tests based on somatic cell counts compared to normal quarters (values represent percent of normal): total solids (92), lactose (85), fat (88), total protein (100), caseins (82), whey protein (162), chloride (161), sodium (136), potassium (91), pH (105), lipase activity (116), and acid degree value (183).	Potassium	355-364	Weaning weight-maternal milk	Bos taurus	53-57
612271-4	1977	These observations demonstrate that impairement of growth hormone responses to stimulation occur in Bartter"s syndrome with potassium depletion.	Potassium	124-133	growth hormone 1	Homo sapiens	51-65
10725-6	1976	An increase in plasma potassium concentration may reduce plasma renin concentration, but this appeared to be overruled by the stimulating effect of sodium depletion.	Potassium	22-31	renin	Homo sapiens	64-69
830994-7	1977	Phospholipase A activity, which was depressed in potassium-depleted animals, increased in each renal zone by 12 hours after potassium repletion.	Potassium	49-58	phospholipase A and acyltransferase 1	Rattus norvegicus	0-15
830994-7	1977	Phospholipase A activity, which was depressed in potassium-depleted animals, increased in each renal zone by 12 hours after potassium repletion.	Potassium	124-133	phospholipase A and acyltransferase 1	Rattus norvegicus	0-15
847391-2	1977	0.5 IE insulin/kg bodyweight intravenously was followed by an immediate gastric relaxation, obvious before any marked decrease of blood glucose or plasma potassium occurred, and furthermore not affected by administration of glucose or potassium.	Potassium	154-163	insulin	Canis lupus familiaris	7-14
793839-3	1976	Ahigh potassium concentration (56mM) induces an increase in LHRH release from entire pieces of mediobasal hypothalamus (MBH), but not from a synaptosomal pellet; this release is inhibited when calcium is omitted.	Potassium	6-15	gonadotropin releasing hormone 1	Rattus norvegicus	60-64
871531-4	1977	Contractions produced by exogenous norepinephrine or serotonin in a potassium-free bath were also made to relax by the addition of potassium.	Potassium	68-77	neurogenin 3	Rattus norvegicus	106-111
871531-4	1977	Contractions produced by exogenous norepinephrine or serotonin in a potassium-free bath were also made to relax by the addition of potassium.	Potassium	131-140	neurogenin 3	Rattus norvegicus	106-111
137413-4	1976	The changes that occurred in the erythorcyte sodium concentration and Na-K ATPase activity were not random since they correlated significantly with changes in the active potassium influx.	Potassium	170-179	TANK binding kinase 1	Homo sapiens	70-74
792421-1	1976	This article briefly reviews the effects of potassium on insulin release.	Potassium	44-53	insulin	Homo sapiens	57-64
973876-0	1976	Effect of potassium-sparing diuretics on the renin-angiotensin-aldosterone system and potassium retention in heart failure.	Potassium	10-19	renin	Homo sapiens	45-50
1049558-5	1976	The mean of potassium in the serum of the 16 patients, those having quadriplegias, ran up to 1,7 mval/l (range 1,4-2,5).	Potassium	12-21	RAN, member RAS oncogene family	Homo sapiens	83-86
975493-3	1976	The CPK activity returned to normal values after fluid and potassium replacement.	Potassium	59-68	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	4-7
186587-15	1976	The ionic dependence of the reversal potentials is predicted from an extended constant-field equation using a ratio of sodium:potassium permeabilities of PNa/PK=1-3, and a ratio of magnesium:potassium permeabilities of PMg/PK=4-7.	Potassium	126-135	uncharacterized protein	Drosophila melanogaster	158-164
965491-9	1976	These studies have demonstrated that chronic changes in sodium or potassium balance and acute changes in blood angiotensin II levels can exert modulating effects upon the adrenal content and/or affinity of specific receptor sites for angiotensin II.	Potassium	66-75	angiotensinogen	Rattus norvegicus	234-248
965491-3	1976	High potassium intake was followed by increased serum potassium and markedly elevated plasma aldosterone, with subnormal levels of renin and angiotensin II and a 170% increase in the number of angiotensin II receptors per cell after 1 wk.	Potassium	5-14	renin	Rattus norvegicus	131-155
965491-3	1976	High potassium intake was followed by increased serum potassium and markedly elevated plasma aldosterone, with subnormal levels of renin and angiotensin II and a 170% increase in the number of angiotensin II receptors per cell after 1 wk.	Potassium	5-14	angiotensinogen	Rattus norvegicus	141-155
965491-4	1976	Sodium loading and potassium deprivation were followed by the opposite effect upon adrenal receptors, with reduction of the angiotensin II-binding capacity.	Potassium	19-28	angiotensinogen	Rattus norvegicus	124-138
965491-6	1976	A decrease in receptor affinity was noted after 6 wk of either low sodium or low potassium intake, when the renin and angiotensin II levels were increased by 104-129%.	Potassium	81-90	renin	Rattus norvegicus	108-132
990387-0	1976	Effect of acute sodium or potassium depletion on plasma renin activity in haemodialysed patients.	Potassium	26-35	renin	Homo sapiens	56-61
958001-4	1976	Potassium repletion resulted in improvement of the patient"s glucose tolerance test, with a decrease in the peak glucose level from 184 mg/100ml to 130 mg/100ml and an increase in the peak insulin level from 46 muU/ml to 85 muU/ml.	Potassium	0-9	insulin	Homo sapiens	189-196
196467-0	1976	Effect of potassium on human and rat liver glucose-6-phosphatase.	Potassium	10-19	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	43-64
185465-0	1976	The effect of changes in potassium concentration on the maximal steroidogenic response of purified zona glomerulosa cells to angiotensin II.	Potassium	25-34	angiotensinogen	Homo sapiens	125-139
821964-2	1976	The effect of TRH induced acute elevation of endogenous serum prolactin on renal water, sodium, potassium and total solute excretion was investigated during metabolic balance conditions and during escape form mineralocorticoid excess in 8 normal volunteers (6 males, 2 females)...	Potassium	96-105	prolactin	Homo sapiens	62-71
958001-8	1976	These observations demonstrate that impairment of both insulin and growth hormone responses to stimulation occur in primary aldosteronism with potassium depletion.	Potassium	143-152	growth hormone 1	Homo sapiens	67-81
958001-6	1976	Growth hormone response to arginine infusion was also initially minimal at 12.5 ng/ml, increasing markedly to 26 ng/ml after potassium replenishment.	Potassium	125-134	growth hormone 1	Homo sapiens	0-14
958001-7	1976	Insulin-induced hypoglycemia resulted in a depressed growth hormone response of 8 ng/ml when the patient was potassium-deficient, but a normal response of 30 ng/ml after potassium repletion.	Potassium	109-118	insulin	Homo sapiens	0-7
958001-7	1976	Insulin-induced hypoglycemia resulted in a depressed growth hormone response of 8 ng/ml when the patient was potassium-deficient, but a normal response of 30 ng/ml after potassium repletion.	Potassium	109-118	growth hormone 1	Homo sapiens	53-67
958001-7	1976	Insulin-induced hypoglycemia resulted in a depressed growth hormone response of 8 ng/ml when the patient was potassium-deficient, but a normal response of 30 ng/ml after potassium repletion.	Potassium	170-179	insulin	Homo sapiens	0-7
181985-1	1976	Five patients with pseudohypoparathyroidism were compared to normal subjects and patients with hypoparathyroidism in their ability to respond to the infusion of parathyroid hormone (PTH) by altering excretion of calcium, sodium, potassium, phosphate and bicarbonate.	Potassium	229-238	parathyroid hormone	Homo sapiens	161-180
955110-0	1976	Ligand partitioning into membranes: its significance in determining Km and Ks values for cytochrome P-450 and other membrane bound receptors and enzymes.	Potassium	75-77	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	89-105
954850-1	1976	In slices of rat occipital cortex preincubated with 3H-noradrenaline, methioine-enkephalin diminished the overflow of tritium evoked by electrical field stimulation or by 20 mM potassium.	Potassium	177-186	proenkephalin	Rattus norvegicus	80-90
952282-6	1976	Urinary kallikrein concentration was significantly lower in black children than in white children (p less than 0.001) and was positively correlated with urinary creatinine and urinary potassium and inversely related to urinary sodium concentrations.	Potassium	184-193	kallikrein related peptidase 4	Homo sapiens	8-18
1085646-10	1976	6 Tension development gradually occurred in relaxed potassium-depolarized muscle preparations exposed to 20 muM X-537A.	Potassium	52-61	latexin	Homo sapiens	108-111
937206-3	1976	The glucose-insulin-potassium solution was composed of 300 g of glucose, 50 units of regular insulin and 80 mEq of potassium ion per liter, and was infused at a rate of 1.5 ml/kg per hour through the right atrial port of an indwelling Swan-Ganz thermodilution catheter.	Potassium	20-29	insulin	Homo sapiens	12-19
940019-0	1976	Plasma renin activity in normal children: its relationship to age and rates of excretion of sodium and potassium.	Potassium	103-112	renin	Homo sapiens	7-12
958507-0	1976	Persistent enhancement of potassium-induced responses of the rat vas deferens by desipramine.	Potassium	26-35	arginine vasopressin	Rattus norvegicus	65-68
182488-4	1976	Since the apparent optical and EPR binding constants agree very well (Ks approximately 2-10(-5) M), and metyrapone is found to displace the spin label, we conclude, that the spin label binds to the active site of cytochrome P-450.	Potassium	70-72	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	213-229
958507-1	1976	The effect of desipramine on the cumulative dose-response curves of noradrenaline and potassium (K+) was examined on the isolated rat vas deferens.	Potassium	86-95	arginine vasopressin	Rattus norvegicus	134-137
769633-4	1976	Our studies emphasize the crucial roles played by insulin and aldosterone in regulating the serum potassium concentration in man, and the need to avoid hyperglycemia in patients with combined insulin and aldosterone deficiency.	Potassium	98-107	insulin	Homo sapiens	50-57
138459-1	1976	The interconnections between EEG, intermediary and energy metabolism of the brain cortex and CSF potassium level are studied during severe hypercapnia in anaesthetized, artificially ventilated cats.	Potassium	97-106	granulocyte-macrophage colony-stimulating factor	Felis catus	93-96
138459-4	1976	The CSF potassium concentration is raised and the changes in metabolism suggest an acidosis-induced inhibition of phosphofructokinase and, probably, of hexokinase.	Potassium	8-17	granulocyte-macrophage colony-stimulating factor	Felis catus	4-7
138459-8	1976	After termination of CO2 inhalation the EEG reappears, the CSF potassium concentration normalizes, and the inhibition of the glycolytic enzymes disappears.	Potassium	63-72	granulocyte-macrophage colony-stimulating factor	Felis catus	59-62
1082887-2	1976	These observations suggested that PHA might induce an increase in the exodus of intracellular potassium during incubation in physiologic media.	Potassium	94-103	lamin B receptor	Homo sapiens	34-37
983613-2	1976	The Ks values for both substances and consequently the affinity for cytochrome P-450 do not change during ageing.	Potassium	4-6	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	68-84
1248655-3	1976	Aldosterone regulates kallikrein excretion, as normal subjects show increased kallikrein excretion in response to a low sodium intake, high potassium intake, or the synthetic mineralocorticoid, fludrocortisone, whereas kallikrein excretion falls during treatment with spironolactone.	Potassium	140-149	kallikrein related peptidase 4	Homo sapiens	78-88
1248655-3	1976	Aldosterone regulates kallikrein excretion, as normal subjects show increased kallikrein excretion in response to a low sodium intake, high potassium intake, or the synthetic mineralocorticoid, fludrocortisone, whereas kallikrein excretion falls during treatment with spironolactone.	Potassium	140-149	kallikrein related peptidase 4	Homo sapiens	78-88
1247857-4	1976	The infusion produced an average fall in plasma potassium from 3-99 to 3-10 mmol/l, which was associated with an increase in plasma glucose and serum insulin, suggesting that this arose from a shift of potassium from the extracellular to the intracellular space.	Potassium	202-211	insulin	Homo sapiens	150-157
1032572-5	1976	The results reduction in plasma renin concentration would in turn lead to a drop in aldosterone secretion rate indicated by the increase in potassium and decrease in sodiummour data would support such a sequence of events.	Potassium	140-149	renin	Homo sapiens	32-37
1245602-2	1976	The 31 normal subjects were in balance on a daily intake of 200 meg sodium and 100 meq potassium to suppress endogenous renin.	Potassium	87-96	renin	Homo sapiens	120-125
1249599-7	1976	DAP amplitude increases as the cell is hyperpolarized beyond the potassium equilibrium potential.	Potassium	65-74	death associated protein	Homo sapiens	0-3
7752-0	1976	Mechanisms of tyrosine hydroxylase and dopamine beta-hydroxylase induction in organ cultures of rat sympathetic ganglia by potassium depolarization and cholinomimetics.	Potassium	123-132	tyrosine hydroxylase	Rattus norvegicus	14-34
7752-0	1976	Mechanisms of tyrosine hydroxylase and dopamine beta-hydroxylase induction in organ cultures of rat sympathetic ganglia by potassium depolarization and cholinomimetics.	Potassium	123-132	dopamine beta-hydroxylase	Rattus norvegicus	39-64
7752-1	1976	It was the aim of the present study to elucidate the mechanisms involved in specific tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) induction by potassium depolarization and cholinomimetics in rat superior cervical ganglia kept in organ culture.	Potassium	160-169	tyrosine hydroxylase	Rattus norvegicus	85-105
7752-1	1976	It was the aim of the present study to elucidate the mechanisms involved in specific tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) induction by potassium depolarization and cholinomimetics in rat superior cervical ganglia kept in organ culture.	Potassium	160-169	tyrosine hydroxylase	Rattus norvegicus	107-109
7752-1	1976	It was the aim of the present study to elucidate the mechanisms involved in specific tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) induction by potassium depolarization and cholinomimetics in rat superior cervical ganglia kept in organ culture.	Potassium	160-169	dopamine beta-hydroxylase	Rattus norvegicus	115-140
7752-1	1976	It was the aim of the present study to elucidate the mechanisms involved in specific tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) induction by potassium depolarization and cholinomimetics in rat superior cervical ganglia kept in organ culture.	Potassium	160-169	dopamine beta-hydroxylase	Rattus norvegicus	142-145
7752-2	1976	The effect of high (54 mM) potassium concentration on intact ganglia seems to result in a dual action: a) a specific induction of TH and DBH via release of acetylcholine from preganglionic cholinergic nerve terminals.	Potassium	27-36	tyrosine hydroxylase	Rattus norvegicus	130-132
7752-2	1976	The effect of high (54 mM) potassium concentration on intact ganglia seems to result in a dual action: a) a specific induction of TH and DBH via release of acetylcholine from preganglionic cholinergic nerve terminals.	Potassium	27-36	dopamine beta-hydroxylase	Rattus norvegicus	137-140
131349-1	1976	Potassium (100 mM KC1) contracture of the isolated rat right ventricle was lower in Tyrode solution (37 mM Na)  than on substituting sucrose (270 mM) for NaC1 and was biphasic in 70% of the experiments.	Potassium	0-9	nucleus accumbens associated 1	Rattus norvegicus	154-158
1204282-4	1975	Reduced potassium intake was associated with a significant increase in circulating renin activity and angiotensin II concentration and a significant reduction in renal blood flow.	Potassium	8-17	renin	Homo sapiens	83-88
1204282-4	1975	Reduced potassium intake was associated with a significant increase in circulating renin activity and angiotensin II concentration and a significant reduction in renal blood flow.	Potassium	8-17	angiotensinogen	Homo sapiens	102-116
1271623-1	1976	In 73 patients with hypertensive and ischemic heart diseases the total body potassium content was studied by measuring natural radioactivity with reference to K40 before and after administration of quinidine, isoptin and inderal.	Potassium	76-85	keratin 40	Homo sapiens	159-162
948788-0	1976	[Effect of insulin on total potassium level in patients with diabetes mellitus].	Potassium	28-37	insulin	Homo sapiens	11-18
53719-8	1975	However, small doses of insulin led to a poor retention of potassium.	Potassium	59-68	insulin	Homo sapiens	24-31
1214279-6	1975	On the other hand, carboxypeptidases A and B, both at 1mg/ml, suppressed the sodium and potassium conductance increases with little or no change in sodium inactivation.	Potassium	88-97	carboxypeptidase B1	Homo sapiens	19-44
1204282-7	1975	Reduced potassium intake decreased both the renal vascular and the adrenal response to infused angiotensin II.	Potassium	8-17	angiotensinogen	Homo sapiens	95-109
1204282-10	1975	The results suggest an important influence of potassium-induced renin-angiotensin system responses on both the renal vasculature and adrenal glomerulosa cell in normal man.	Potassium	46-55	renin	Homo sapiens	64-69
1245602-6	1976	P113 also reduced the clearance of para-aminohippurate, creatinine, sodium, and potassium, a pattern similar to that induced by A II.	Potassium	80-89	signal transducer and activator of transcription 2	Homo sapiens	0-4
1200041-2	1975	Severe hyperkalemia associated with spontaneous hyperglycemia as well as with the intravenous infusions of glucose occurred in an insulin-requiring diabetic patient in the absence of potassium administration, the use of diuretics which inhibit urinary potassium excretion or acidemia.	Potassium	252-261	insulin	Homo sapiens	130-137
1200041-5	1975	In this patient, the serum potassium concentration increases after the intravenous infusions of glucose because there is insufficient aldosterone and insulin to reverse the transfer of potassium to the extracellular fluid which normally occurs after hypertonic infusions of glucose.	Potassium	27-36	insulin	Homo sapiens	150-157
811755-6	1975	In cells with an osmolality of 300-350 mOs, the regulatory volume decrease is caused primarily by a passive efflux of potassium and anions due to increased membrane permeability to potassium.	Potassium	118-127	Moloney sarcoma oncogene	Mus musculus	39-42
1291-3	1975	The data on cerebral vascular responses to microapplication of mCSF solutions with various pH, potassium and catecholamines concentrations, suggest that rapid regulatory chains may be conditioned by potassium and neurogenic vascular effects, while slow ones could be mediated by CO2 and related pH changes.	Potassium	95-104	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	63-67
1291-3	1975	The data on cerebral vascular responses to microapplication of mCSF solutions with various pH, potassium and catecholamines concentrations, suggest that rapid regulatory chains may be conditioned by potassium and neurogenic vascular effects, while slow ones could be mediated by CO2 and related pH changes.	Potassium	199-208	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	63-67
1230136-3	1975	The insulin-like effect of lithium on carbohydrate metabolism and correlated ions (phosphates, calcium, magnesium, potassium) at cell membrane level is then discussed.	Potassium	115-124	insulin	Homo sapiens	4-11
811755-6	1975	In cells with an osmolality of 300-350 mOs, the regulatory volume decrease is caused primarily by a passive efflux of potassium and anions due to increased membrane permeability to potassium.	Potassium	181-190	Moloney sarcoma oncogene	Mus musculus	39-42
1058211-0	1975	Effect of human lysozyme (muramidase) on potassium handling by the perfused rat kidney.	Potassium	41-50	lysozyme	Homo sapiens	16-24
126237-0	1975	Structural studies of sodium and potassium ion-activated adenosine triphosphatase.	Potassium	33-42	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	57-81
126237-2	1975	Sodium and potassium ion-activated adenosine triphosphatase is the enzyme responsible for the active transport of sodium and potassium across the plasma membrane.	Potassium	11-20	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	35-59
1058211-2	1975	Purified human lysozyme (muramidase) stimulated potassium excretion by the isolated perfused rat kidney.	Potassium	48-57	lysozyme	Homo sapiens	15-23
1228745-1	1975	A method of radiometry of the whole body in the low-background chamber was applied to the study of the content of total potassium (by K40) in the organism of 67 patients suffering from diabetes mellitus of various severity and in 76 healthy individuals.	Potassium	120-129	keratin 40	Homo sapiens	134-137
1228745-4	1975	Total potassium level had a tendency to normalization after treatment with insulin, potassium salts and vitamins.	Potassium	6-15	insulin	Homo sapiens	75-82
1084297-7	1975	Vasopressin and aldosterone increase the potassium secretion.	Potassium	41-50	arginine vasopressin	Homo sapiens	0-11
240656-6	1975	From the relative KS values, it is concluded that metyrapone and carbon monoxide interact with reduced cytochrome P-450 more tenaciously than nitro compounds.	Potassium	18-20	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	103-119
169125-3	1975	Insulin release was increased 2-4 fold by 40 mM potassium in the presence of calcium, glucose (22 mM), glucagon (0.3-3.0 muM), N6,02"-dibutyryl adenosine 3",5"-monophosphate (cAMP; 6mM), and theophylline (10 mM).	Potassium	48-57	insulin	Mesocricetus auratus	0-7
1159371-7	1975	In connective, potassium entry was extremely slow, with a half-time greater than 100 min, while potassium efflux was relatively rapid (T 1/2 = 6 min).	Potassium	96-105	interleukin 1 receptor like 1	Homo sapiens	135-148
1147438-1	1975	Effects of potassium and sodium replacement on the renin-angiotensin-aldosterone system.	Potassium	11-20	renin	Homo sapiens	51-56
1150875-1	1975	Potassium has been shown to suppress plasma renin activity (PRA).	Potassium	0-9	renin	Homo sapiens	44-49
807496-0	1975	Early insulin release and its response to potassium supplementation in protein-calorie malnutrition.	Potassium	42-51	insulin	Homo sapiens	6-13
1167307-1	1975	The present study was performed to assess the sensitivity of the renin-angiotensin-aldosterone axis to small changes in plasma potassium concentration within the physiologic range.	Potassium	127-136	renin	Homo sapiens	65-70
1167307-14	1975	The data also document that acute changes in extracellular potassium concentration play a role in the regulation of renin secretion.	Potassium	59-68	renin	Homo sapiens	116-121
166728-4	1975	Potassium-induced depolarization (45 mM K-+) also increases MAO activity; but the extent of the increase depends upon (NGF concentration, for there is little or no increase at high NGF concentrations.	Potassium	0-9	nerve growth factor	Gallus gallus	119-122
166728-4	1975	Potassium-induced depolarization (45 mM K-+) also increases MAO activity; but the extent of the increase depends upon (NGF concentration, for there is little or no increase at high NGF concentrations.	Potassium	0-9	nerve growth factor	Gallus gallus	181-184
807496-3	1975	This suggests that impaired insulin secretion in PMC is in part due to a potassium mediated disturbance of insulin release.	Potassium	73-82	insulin	Homo sapiens	28-35
1173310-0	1975	Effects of calcium and sodium on vasopressin release in vitro induced by a prolonged potassium stimulation.	Potassium	85-94	arginine vasopressin	Rattus norvegicus	33-44
1124397-0	1975	Mechanism of insulin-induced paralysis of muscles from potassium-depleted rats.	Potassium	55-64	insulin	Homo sapiens	13-20
1124397-1	1975	Zinc-free insulin elicited a reduction in the potassium conductance of muscle fibers from potassium-depleted muscle, which led to depolarization, blockage of action-poteintial mechanism, and paralysis.	Potassium	46-55	insulin	Homo sapiens	10-17
1124397-1	1975	Zinc-free insulin elicited a reduction in the potassium conductance of muscle fibers from potassium-depleted muscle, which led to depolarization, blockage of action-poteintial mechanism, and paralysis.	Potassium	90-99	insulin	Homo sapiens	10-17
1122880-2	1975	Prolactin administration significantly stimulated fluid, sodium,potassium, calcium, magnesium and chloride transport across everted jejunal sacs.	Potassium	64-73	prolactin	Rattus norvegicus	0-9
1130719-9	1975	The data suggest that the renin-angiotensin-aldosterone system may play a role in blood pressure regulation during cardiopulmonary bypass and may result in the excessive urinary excretion of potassium and decrease in plasma potassium levels.	Potassium	191-200	renin	Homo sapiens	26-31
1130719-9	1975	The data suggest that the renin-angiotensin-aldosterone system may play a role in blood pressure regulation during cardiopulmonary bypass and may result in the excessive urinary excretion of potassium and decrease in plasma potassium levels.	Potassium	224-233	renin	Homo sapiens	26-31
167274-0	1975	Blockade by ouabain or elevated potassium ion concentration of the adrenergic and adenosine cyclic 3",5"-monophosphate-induced stimulation of pineal serotonin N-acetyltransferase activity.	Potassium	32-41	aralkylamine N-acetyltransferase	Homo sapiens	149-178
235594-2	1975	Two of these membrane-associated enzymes, glyceraldehyde phosphate dehydrogenase (GAPD) and phosphoglyceric kinase (PGK), have been shown to have controlling functions on intra-erythrocytic glycolysis and sodium-potassium transport.	Potassium	212-221	glyceraldehyde-3-phosphate dehydrogenase	Mus musculus	42-80
235594-2	1975	Two of these membrane-associated enzymes, glyceraldehyde phosphate dehydrogenase (GAPD) and phosphoglyceric kinase (PGK), have been shown to have controlling functions on intra-erythrocytic glycolysis and sodium-potassium transport.	Potassium	212-221	glyceraldehyde-3-phosphate dehydrogenase	Mus musculus	82-86
168058-5	1975	However, the direct effects of sodium and potassium upon renin release were not conspicuous.	Potassium	42-51	renin	Rattus norvegicus	57-62
1120786-8	1975	Urinary potassium (UKV) and phosphate (UPV) excretion were also both decreased during insulin administration; UKV decreased from 66 plus or minus 9 to 21 plus or minus 1 mueq/min (P smaller than 0.005), and tupv decreased from 504 plus or minus 93 to 230 plus or minus 43 mug/min (P smaller than 0.01).	Potassium	8-17	insulin	Homo sapiens	86-93
234807-2	1975	Changes in sodium and potassium balance were related to changes in blood pressure, plasma renin activity, hematocrit, and kidney histology.	Potassium	22-31	renin	Rattus norvegicus	90-95
16659118-1	1975	Short term (10 min) influx of (86)Rb-labeled potassium into corn (Zea mays L. WF9 x M14) root segments was inhibited by La (NO(3))(3) or LaCl(3).	Potassium	45-54	MADS14	Zea mays	84-87
1168128-4	1975	Bovine growth hormone and ovine prolactin produce essentially similar effects in intact rats: significant increases in fluid, sodium and calcium transport in the duodenum; in fluid, sodium and potassium transport in the jejunum; in sodium, chloride, potassium and calcium transport in the ileum.	Potassium	193-202	gonadotropin releasing hormone receptor	Rattus norvegicus	7-21
1168128-4	1975	Bovine growth hormone and ovine prolactin produce essentially similar effects in intact rats: significant increases in fluid, sodium and calcium transport in the duodenum; in fluid, sodium and potassium transport in the jejunum; in sodium, chloride, potassium and calcium transport in the ileum.	Potassium	193-202	prolactin	Bos taurus	32-41
1168128-4	1975	Bovine growth hormone and ovine prolactin produce essentially similar effects in intact rats: significant increases in fluid, sodium and calcium transport in the duodenum; in fluid, sodium and potassium transport in the jejunum; in sodium, chloride, potassium and calcium transport in the ileum.	Potassium	250-259	gonadotropin releasing hormone receptor	Rattus norvegicus	7-21
1168128-4	1975	Bovine growth hormone and ovine prolactin produce essentially similar effects in intact rats: significant increases in fluid, sodium and calcium transport in the duodenum; in fluid, sodium and potassium transport in the jejunum; in sodium, chloride, potassium and calcium transport in the ileum.	Potassium	250-259	prolactin	Bos taurus	32-41
167590-0	1975	Impaired renal response to parathyroid hormone in potassium depletion.	Potassium	50-59	parathyroid hormone	Rattus norvegicus	27-46
1167491-15	1975	The subsequent loss of the retained sodium and potassium during the development of severe hypertension could have facilitated the rise in peripheral plasma renin activity, but did not initiate this rise.	Potassium	47-56	renin	Rattus norvegicus	156-161
1123719-1	1975	Chronic postganglionic denervation of the rate vas deferens produces an increase in the sensitivity of the in vitro smooth muscle to norepinephrine, methoxamine, acetylcholine, potassium and electrical stimulation.	Potassium	177-186	arginine vasopressin	Rattus norvegicus	47-50
1117422-3	1975	Incubation of the slices in a potassium-rich solution (140 mM) resulted in the release of both NE and DBH into the medium.	Potassium	30-39	dopamine beta-hydroxylase	Homo sapiens	102-105
1229805-1	1975	The effect of propranolol on adrenaline- and insulin-induced changes in blood glucose pyruvate, lactate, phosphorus and potassium were examined in 29 apparently healthy volunteers.	Potassium	120-129	insulin	Homo sapiens	45-52
1229805-3	1975	There was no significant change in the blood glucose curve after insulin whereas insulin-induced increases in pyruvate and lactate were reduced by 44% +/- 17.7 (mean +/- SEM) and 78% +/- 5.4 respectively, and the fall in phosphorus by 48% +/- 3.1; the decrease in potassium, however, was not significantly modified.	Potassium	264-273	insulin	Homo sapiens	81-88
1232875-3	1975	Several  factors take a part in the regulation of renin secretion (mean arterial pressure, introduction of sodium and potassium, the sympathetic nervous system, ADH and concentration of angiotensin II in plasma).	Potassium	118-127	renin	Homo sapiens	50-55
182367-8	1975	An insulin-induced configurational change in the plasma membrane could simultaneously account for the effects of insulin on sodium and potassium permeability and the action on facilitated transport.	Potassium	135-144	insulin	Homo sapiens	3-10
182367-8	1975	An insulin-induced configurational change in the plasma membrane could simultaneously account for the effects of insulin on sodium and potassium permeability and the action on facilitated transport.	Potassium	135-144	insulin	Homo sapiens	113-120
163880-3	1975	Insulin release from the pancreatic tissue of decapitated foetuses was significantly greater than that from the pancreas of control litter-mates when incubated in media containing 3-3mM-glucose, 16-5mM-glucose or 16-5mM-glucose plus 5 mug glucagon/ml, but was similar when the incubation medium contained 3-3 or 16-5 mM-glucose plus 1 mM-theophylline or 3-3mM-glucose plus 60 mM-potassium.	Potassium	379-388	insulin	Oryctolagus cuniculus	0-7
1101088-9	1975	A direct or an indirect effect of potassium ion may be responsible for the hypersecretion or aldosterone rather than the renin-angiotensin system.	Potassium	34-43	renin	Homo sapiens	121-126
167590-1	1975	In potassium depletion, a possible alteration of the proximal tubular response to parathyroid hormone (PTH) was evaluated in rat kidney.	Potassium	3-12	parathyroid hormone	Rattus norvegicus	82-101
167590-1	1975	In potassium depletion, a possible alteration of the proximal tubular response to parathyroid hormone (PTH) was evaluated in rat kidney.	Potassium	3-12	parathyroid hormone	Rattus norvegicus	103-106
167590-4	1975	2) There was a lesser increase of cyclic AMP concentration by PTH in potassium-depleted slices, indicating the lesser urinary cyclic AMP was due to the specific impairment of PTH-dependent cyclic AMP in the kidney.	Potassium	69-78	parathyroid hormone	Rattus norvegicus	62-65
167590-4	1975	2) There was a lesser increase of cyclic AMP concentration by PTH in potassium-depleted slices, indicating the lesser urinary cyclic AMP was due to the specific impairment of PTH-dependent cyclic AMP in the kidney.	Potassium	69-78	parathyroid hormone	Rattus norvegicus	175-178
167590-8	1975	All above results indicate that, in potassium depletion, the renal response to PTH is impaired, and the impairment is both within the step of cyclic AMP generation and after the cyclic AMP generation.	Potassium	36-45	parathyroid hormone	Rattus norvegicus	79-82
4216389-4	1974	Whole-body potassium (ratio of observed to expected) was initially reduced in most of the patients requiring insulin.	Potassium	11-20	insulin	Homo sapiens	109-116
4216389-6	1974	The increase in whole-body potassium in the individual patients varied over a wide range, and in patients who were treated with insulin it was often of a similar magnitude to that observed in patients in diabetic ketoacidosis.	Potassium	27-36	insulin	Homo sapiens	128-135
4533064-0	1974	Letter: Initiation of the potassium-depleted state of the cirrhotic-a carbohydrate, insulin and aldosterone conspiracy?	Potassium	26-35	insulin	Homo sapiens	84-91
4155067-3	1974	In the present experiments, we found that crude preparations of tyrosine hydroxylase isolated from guinea pig vasa deferentia that were electrically stimulated or depolarized by potassium show an increase in activity compared with enzyme obtained from untreated paired control tissues.	Potassium	178-187	tyrosine 3-monooxygenase	Cavia porcellus	64-84
4458428-1	1974	Total Exchangeable Potassium (TEK) was measured in 31 elderly patients admitted to a geriatric assessment unit.	Potassium	19-28	TEK receptor tyrosine kinase	Homo sapiens	30-33
165438-1	1975	The relationship between plasma potassium concentration and the renin-angiotensin-aldosterone system was evaluated in ten patients with chronic renal failure (creatinine clearance 10-56 ml/min).	Potassium	32-41	renin	Homo sapiens	64-69
165438-4	1975	The data suggest that the maintenance of plasma potassium levels in these patients is dependent of the presence of a normally functioning renin-angiotensin-aldosterone system; aldosterone activity may be an important determinant of sodium conservation in patients with renal failure.	Potassium	48-57	renin	Homo sapiens	138-143
4155067-7	1974	The increase in activity produced by addition of Ca(++) to the isolated enzyme or by electrical stimulation or potassium depolarization of the tissue before isolation of the enzyme appears to be mediated by changes in the kinetic properties of tyrosine hydroxylase.	Potassium	111-120	tyrosine 3-monooxygenase	Cavia porcellus	244-264
4140229-6	1974	Removal of sodium or potassium from Krebs solution markedly inhibited the transport of DBH.	Potassium	21-30	dopamine beta-hydroxylase	Homo sapiens	87-90
4426701-7	1974	Large amounts of potassium and nucleotides were rapidly lost by each type of cell when treated with 20 mug of lysozyme per ml.	Potassium	17-26	lysozyme	Homo sapiens	110-118
4429142-0	1974	Acute effects of vasopressin on potassium and water balance in rats with diabetes insipidus.	Potassium	32-41	arginine vasopressin	Rattus norvegicus	17-28
4817354-2	1974	Normal human red cells which have had their intracellular sodium (Na(c)) reduced have a diminished Na-K pump rate, but only if intracellular potassium (K(c)) is high.	Potassium	141-150	X-linked Kx blood group	Homo sapiens	66-71
4367700-0	1974	[Influence of angiotensin II-infusion on the sodium- and potassium level in plasma and erythrocytes of normotensive persons and patients with essential hypertension (author"s transl)].	Potassium	57-66	angiotensinogen	Homo sapiens	14-28
4414038-4	1974	Potassium current was usually blocked by perfusion with CsF, but some experiments were done with intact axons.	Potassium	0-9	colony stimulating factor 2	Homo sapiens	56-59
4817354-4	1974	Cells with reduced Na(c) and high K(c) have an unchanged Na efflux if external potassium (K(ext)) is removed.	Potassium	79-88	X-linked Kx blood group	Homo sapiens	19-24
4756157-0	1973	[Effect of parathyroid hormone on urinary sodium and potassium excretion in hypothyroid children].	Potassium	53-62	parathyroid hormone	Homo sapiens	11-30
4809620-0	1974	Effect of intrapancreatic injection of potassium and calcium on insulin and glucagon secretion in dogs.	Potassium	39-48	insulin	Canis lupus familiaris	64-71
4799348-1	1973	Mode of insulin action on the cell: separative effect of insulin on potassium and glucose transfer of myocardium.	Potassium	68-77	insulin	Homo sapiens	57-64
4710366-0	1973	Evidence for a role of endogenous insulin and glucagon in the regulation of potassium homeostasis.	Potassium	76-85	insulin	Homo sapiens	34-41
4719217-1	1973	Using a triple-lumen tube perfusion technique in normal human subjects secretin (2U/kg/hour intravenously) was shown to reduce the absorption of sodium, potassium, and chloride in the most proximal 30 cm of jejunum but it had no effect on bicarbonate absorption.	Potassium	153-162	secretin	Homo sapiens	71-79
4378027-1	1972	Phentolamine-induced blockade of alpha-adrenoreceptors and subsequent beta-adrenoreceptor stimulation by intravenous injection of adrenaline or phenylephrine (Mezaton) in anaesthtized dogs was accompanied by an elevation of plasma renin activitiy in peripheral blood and a reduction of renal excretion of sodium, potassium, and water.	Potassium	313-322	renin	Canis lupus familiaris	231-236
4707706-0	1973	Role of insulin in the transfer of infused potassium to tissue.	Potassium	43-52	insulin	Homo sapiens	8-15
4202811-0	1973	Effect of cholinesterase inhibitors on active potassium influx in monkey erythrocytes.	Potassium	46-55	butyrylcholinesterase	Homo sapiens	10-24
5084885-0	1972	Effects of renal arterial infusion of sodium and potassium on renin secretion in the dog.	Potassium	49-58	renin	Canis lupus familiaris	62-67
4556620-0	1972	Serum immunoreactive insulin and growth hormone response to potassium infusion in normal man.	Potassium	60-69	growth hormone 1	Homo sapiens	33-47
5029445-0	1972	[Sensitization of posterior root fibers to the stimulating action of potassium ions caused by bradykinin and acetylcholine].	Potassium	69-78	kininogen 1	Homo sapiens	94-104
5076396-10	1972	Noradrenaline (1 muM) markedly increased the efflux of (42)K and within 2 min caused tissue potassium to fall by 8%.	Potassium	92-101	latexin	Homo sapiens	17-20
4263055-0	1972	Effects of incubations in low potassium and low sodium media on Na-K-ATPase activity in snake and chicken kidney slices.	Potassium	30-39	ATPase Na+/K+ transporting subunit alpha 1	Gallus gallus	64-75
5006916-0	1972	Fourier transform C-13 NMR analysis of some free and potassium-ion complexed antibiotics.	Potassium	53-62	homeobox C13	Homo sapiens	18-22
5032187-0	1972	Different effect of potassium and calcium ion on the release of growth hormone and prolactin from isolated rat pituitaries in vitro.	Potassium	20-29	gonadotropin releasing hormone receptor	Rattus norvegicus	64-78
5032187-0	1972	Different effect of potassium and calcium ion on the release of growth hormone and prolactin from isolated rat pituitaries in vitro.	Potassium	20-29	prolactin	Rattus norvegicus	83-92
4256160-0	1971	Electron-microscopic histochemical examination of potassium-sodium-dependent myocardial ATP-ase activity.	Potassium	50-59	dynein axonemal heavy chain 8	Homo sapiens	88-95
4255317-0	1971	Binding of adenosine triphosphate to sodium and potassium ion-stimulated adenosine triphosphatase.	Potassium	48-57	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	73-97
5553103-1	1971	2,4,6-Trinitro-3-methyl-phenol (trinitrocresol, H(+)TNC(-)) was found to inhibit anion and stimulate cation movements across the membranes of both high potassium (HK) and low potassium (LK) sheep red blood cells.	Potassium	152-161	tenascin	Ovis aries	52-55
5553103-1	1971	2,4,6-Trinitro-3-methyl-phenol (trinitrocresol, H(+)TNC(-)) was found to inhibit anion and stimulate cation movements across the membranes of both high potassium (HK) and low potassium (LK) sheep red blood cells.	Potassium	175-184	tenascin	Ovis aries	52-55
5553103-6	1971	TNC(-) also inhibited the ouabain-sensitive potassium influx.	Potassium	44-53	tenascin	Ovis aries	0-3
4945186-2	1971	Undelayed beta-galactosidase formation was found in stringent auxotrophs recovering from amino acid starvation, in cells recovering from glycerol or potassium starvation, and in bacteria recovering from puromycin treatment.	Potassium	149-158	galactosidase beta 1	Homo sapiens	10-28
11945632-0	1971	Opposite effects of potassium ions on the affinities of rat liver serine dehydratase for coenzyme and substrate.	Potassium	20-29	serine dehydratase	Rattus norvegicus	66-84
4319969-8	1970	Therefore, the effect seems to be mediated by a direct influence of potassium ions on renal renin secretion, perhaps via induced changes in sodium load to the macula densa.These studies point to an important role for potassium in the regulation of renin secretion.	Potassium	217-226	renin	Rattus norvegicus	92-97
5101297-0	1971	On the mechanism of renal potassium wasting in renal tubular acidosis associated with the Fanconi syndrome (type 2 RTA).	Potassium	26-35	RNA binding fox-1 homolog 2	Homo sapiens	115-118
5101297-1	1971	The mechanism of renal potassium wasting in renal tubular acidosis associated with the Fanconi syndrome (type 2 RTA) was investigated in 10 patients, each of whom had impaired proximal renal tubular reabsorption of bicarbonate as judged from a greater than 15-20% reduction of renal tubular bicarbonate reabsorption (THCO(3) (-)) at normal plasma bicarbonate concentrations.	Potassium	23-32	RNA binding fox-1 homolog 2	Homo sapiens	112-115
5496279-0	1970	Early stimulation of potassium uptake in lymphocytes treated with PHA.	Potassium	21-30	lamin B receptor	Homo sapiens	66-69
4319969-3	1970	With less consistency, the highest sodium intake employed (52 mEq Na(+)/100 g food) tended to induce potassium depletion.In accordance with previous reports, sodium deprivation induced significant increases in plasma renin activity.	Potassium	101-110	renin	Rattus norvegicus	217-222
5101297-8	1971	These results provide evidence that renal potassium wasting in type 2 RTA is physiologically separable from that in type 1 RTA and in part the result of a reduction in the rate at which the proximal tubule reabsorbs bicarbonate and the distal delivery of supernormal amounts of sodium bicarbonate.	Potassium	42-51	RNA binding fox-1 homolog 2	Homo sapiens	70-73
5501492-10	1970	In 1.8 mM calcium, growth hormone secretion by pituitaries of males and females was markedly stimulated by increased potassium, but it was not appreciably affected by high potasium in low calcium.	Potassium	117-126	gonadotropin releasing hormone receptor	Rattus norvegicus	19-33
5501492-12	1970	Secretion of prolactin and growth hormone by rat adenohypophyses is dependent upon calcium, but only growth hormone secretion is markedly stimulated by increased potassium.	Potassium	162-171	gonadotropin releasing hormone receptor	Rattus norvegicus	101-115
4319969-5	1970	The results describe an inverse relationship between potassium administration and the concurrent level of plasma renin activity.	Potassium	53-62	renin	Rattus norvegicus	113-118
4319969-8	1970	Therefore, the effect seems to be mediated by a direct influence of potassium ions on renal renin secretion, perhaps via induced changes in sodium load to the macula densa.These studies point to an important role for potassium in the regulation of renin secretion.	Potassium	217-226	renin	Rattus norvegicus	248-253
4319969-6	1970	The highest serum renin levels of all occurred in the potassium-depleted animals and the usual renin response to sodium deprivation was virtually abolished in the presence of a high potassium diet.	Potassium	54-63	renin	Rattus norvegicus	18-23
4320973-9	1970	If potassium concentration was increased 10-fold, a 215% increase in growth hormone release was observed.	Potassium	3-12	gonadotropin releasing hormone receptor	Rattus norvegicus	69-83
4320973-10	1970	A combination of hypertonic potassium and 10(-6) M PGE(1) increased growth hormone release 325%, suggesting that potassium and prostaglandins act by independent mechanisms.	Potassium	28-37	gonadotropin releasing hormone receptor	Rattus norvegicus	68-82
4319969-6	1970	The highest serum renin levels of all occurred in the potassium-depleted animals and the usual renin response to sodium deprivation was virtually abolished in the presence of a high potassium diet.	Potassium	182-191	renin	Rattus norvegicus	18-23
4319969-9	1970	The results in turn raise the possibility that renin secretion per se may be importantly involved in effecting potassium conservation and potassium elimination.	Potassium	111-120	renin	Rattus norvegicus	47-52
4319969-6	1970	The highest serum renin levels of all occurred in the potassium-depleted animals and the usual renin response to sodium deprivation was virtually abolished in the presence of a high potassium diet.	Potassium	182-191	renin	Rattus norvegicus	95-100
4320973-10	1970	A combination of hypertonic potassium and 10(-6) M PGE(1) increased growth hormone release 325%, suggesting that potassium and prostaglandins act by independent mechanisms.	Potassium	113-122	gonadotropin releasing hormone receptor	Rattus norvegicus	68-82
4319969-8	1970	Therefore, the effect seems to be mediated by a direct influence of potassium ions on renal renin secretion, perhaps via induced changes in sodium load to the macula densa.These studies point to an important role for potassium in the regulation of renin secretion.	Potassium	68-77	renin	Rattus norvegicus	92-97
4319969-8	1970	Therefore, the effect seems to be mediated by a direct influence of potassium ions on renal renin secretion, perhaps via induced changes in sodium load to the macula densa.These studies point to an important role for potassium in the regulation of renin secretion.	Potassium	68-77	renin	Rattus norvegicus	248-253
4319969-9	1970	The results in turn raise the possibility that renin secretion per se may be importantly involved in effecting potassium conservation and potassium elimination.	Potassium	138-147	renin	Rattus norvegicus	47-52
4320290-0	1970	The relationship of dietary potassium intake to the aldosterone stimulating properties of ACTH.	Potassium	28-37	proopiomelanocortin	Homo sapiens	90-94
4319970-2	1970	Potassium administration reduced plasma renin activity in 18 of 28 studies of both normal and hypertensive subjects.	Potassium	0-9	renin	Homo sapiens	40-45
4319970-4	1970	The renin suppression was related to induced changes in plasma potassium concentration and urinary potassium excretion.	Potassium	63-72	renin	Homo sapiens	4-9
5479370-0	1970	The effect of vasopressin on the reabsorption of sodium, potassium and urea by the renal tubules in man.	Potassium	57-66	arginine vasopressin	Homo sapiens	14-25
4319970-4	1970	The renin suppression was related to induced changes in plasma potassium concentration and urinary potassium excretion.	Potassium	99-108	renin	Homo sapiens	4-9
4319970-6	1970	In six studies potassium deprivation invariably increased plasma renin activity even though a tendency for sodium retention often accompanied this procedure.	Potassium	15-24	renin	Homo sapiens	65-70
4319970-7	1970	The data indicate that both the suppression of plasma renin activity induced by potassium administration and the stimulation of renin activity which follows potassium depletion occur independently of associated changes in either aldosterone secretion or in sodium balance.	Potassium	80-89	renin	Homo sapiens	54-59
4918328-6	1970	60 mM potassium ion, on the other hand, not only restores the insulin secretory response to glucose (200 mg/100 ml) but results in an added stimulation of insulin secretion in the presence of DPH.	Potassium	6-15	insulin	Homo sapiens	62-69
4319970-7	1970	The data indicate that both the suppression of plasma renin activity induced by potassium administration and the stimulation of renin activity which follows potassium depletion occur independently of associated changes in either aldosterone secretion or in sodium balance.	Potassium	157-166	renin	Homo sapiens	128-133
4918328-6	1970	60 mM potassium ion, on the other hand, not only restores the insulin secretory response to glucose (200 mg/100 ml) but results in an added stimulation of insulin secretion in the presence of DPH.	Potassium	6-15	insulin	Homo sapiens	155-162
4319970-8	1970	However, the results do suggest that in various situations, the influence of potassium on plasma renin activity may be either amplified or preempted by changes in sodium balance.	Potassium	77-86	renin	Homo sapiens	97-102
4319970-9	1970	These interactions between potassium and plasma renin could be mediated by an ill-defined extrarenal pathway.	Potassium	27-36	renin	Homo sapiens	48-53
4319970-10	1970	But the findings are more consistent with an intrarenal action of potassium ions to modify renin release.	Potassium	66-75	renin	Homo sapiens	91-96
4319970-12	1970	The effects of potassium ions on renin secretion might also be mediated indirectly via an induced change in tubular sodium transport.	Potassium	15-24	renin	Homo sapiens	33-38
5431662-0	1970	Effects of chronic potassium deficiency on plasma renin activity.	Potassium	19-28	renin	Canis lupus familiaris	50-55
4318964-0	1970	Effect of vasopressin on renal cyclic AMP generation in potassium deficiency and patients with sickle hemoglobin.	Potassium	56-65	arginine vasopressin	Homo sapiens	10-21
5448076-0	1970	Direct effects of potassium on renin secretion and renal function.	Potassium	18-27	renin	Homo sapiens	31-36
5431662-8	1970	Potassium repletion resulted in a prompt decrease in renin activity to predepletion values.	Potassium	0-9	renin	Canis lupus familiaris	53-58
5431662-9	1970	This study indicates that potassium deficiency has a stimulatory effect on renin release that is independent of any effect on sodium balance.	Potassium	26-35	renin	Canis lupus familiaris	75-80
4244314-0	1970	Adenosinetriphosphatase activity of cellular organelles in experimental potassium depletion cardiomyopathy.	Potassium	72-81	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	0-23
4190120-0	1970	Slow potential shifts in dorsal hippocampus during "epileptogenic" perfusion of the inferior horn with high-potassium CSF.	Potassium	108-117	colony stimulating factor 2	Homo sapiens	118-121
5414761-0	1970	Influence of dietary potassium on plasma renin activity in normal man.	Potassium	21-30	renin	Homo sapiens	41-46
5343354-3	1969	Vasopressin contractions are inhibited by replacement of sodium with mannitol or sucrose, elevation of potassium or magnesium concentrations, the presence of the metabolic inhibitors sodium azide and triethyl tin or tetrodotoxin in the bathing fluid.	Potassium	103-112	arginine vasopressin	Rattus norvegicus	0-11
4331448-0	1970	[Effect differences between angiotensin II and noradrenalin in reference to diuresis, sodium and potassium excretion in healthy persons and patients with kidney diseases].	Potassium	97-106	angiotensinogen	Homo sapiens	28-42
5821919-0	1969	Effect of vasopressin on sodium and potassium reabsorption by the renal tubules in man.	Potassium	36-45	arginine vasopressin	Homo sapiens	10-21
19873649-1	1969	The interactions of potassium ions and ATP on transport ATPase activity are discussed, and the interpretation of these interactions is shown to be often ambiguous.	Potassium	20-29	dynein axonemal heavy chain 8	Homo sapiens	56-62
19873649-6	1969	When starved sodium-poor red cells are poisoned with iodoacetamide, loaded with phosphate, and incubated in high-sodium potassium-free media, the ouabain-sensitive efflux of potassium appears to be accompanied by the reversal of the entire ATPase system.	Potassium	174-183	dynein axonemal heavy chain 8	Homo sapiens	240-246
5701380-0	1968	[Changes of potassium in relation to blood sugar and the insulin effect in diabetic children].	Potassium	12-21	insulin	Homo sapiens	57-64
19873649-8	1969	If potassium is present in the external medium, no ouabain-sensitive synthesis of ATP occurs and the ouabain-sensitive efflux of potassium presumably involves the reversal of only the last part of the ATPase system.	Potassium	3-12	dynein axonemal heavy chain 8	Homo sapiens	201-207
19873649-8	1969	If potassium is present in the external medium, no ouabain-sensitive synthesis of ATP occurs and the ouabain-sensitive efflux of potassium presumably involves the reversal of only the last part of the ATPase system.	Potassium	129-138	dynein axonemal heavy chain 8	Homo sapiens	201-207
5736238-0	1968	[Effects of various doses of insulin on potassium and sodium content in the brain tissue and blood serum].	Potassium	40-49	insulin	Homo sapiens	29-36
4176948-0	1968	Effect of potassium on blood-sugar and plasma-insulin levels in patients undergoing peritoneal dialysis and haemodialysis.	Potassium	10-19	insulin	Homo sapiens	46-53
5668632-0	1968	Treatment of angina pectoris of effort with infusion of insulin potassium and dextrose solution.	Potassium	64-73	insulin	Homo sapiens	56-63
4300463-0	1968	[Relation between the blood-pressure effect of angiotensin II and the mean arterial pressure, serum sodium, serum potassium, serum angiotensinase and plasma renin in man].	Potassium	114-123	angiotensinogen	Homo sapiens	47-61
4231042-0	1968	Sodium-potssum tmulated ATPase activity of mammalian hemolysates: clinical observations and ominance of ATPase deficiency in the potassium polymorphism of sheep.	Potassium	129-138	dynein axonemal heavy chain 8	Homo sapiens	104-110
4232206-0	1968	The relation between ouabain-sensitive potassium efflux and the hypothetical dephosphorylation step in the "transport ATPase" system.	Potassium	39-48	dynein axonemal heavy chain 8	Homo sapiens	118-125
5748209-0	1968	[Influence of insulin and vasopressin on potassium distribution in tissues].	Potassium	41-50	insulin	Homo sapiens	14-21
5689153-0	1968	Effect of a synthetic gastrin-like pentapeptide upon the intestinal transport of sodium, potassium, and water.	Potassium	89-98	gastrin	Homo sapiens	22-29
5711901-0	1968	Insulin-potassium effect on gastric acid secretion and antral motility in dogs.	Potassium	8-17	insulin	Canis lupus familiaris	0-7
5711056-0	1968	Pre- and post-convulsive changes in hippocampal excitability induced by localized ventricular perfusion with high potassium CSF.	Potassium	114-123	colony stimulating factor 2	Homo sapiens	124-127
5748209-0	1968	[Influence of insulin and vasopressin on potassium distribution in tissues].	Potassium	41-50	arginine vasopressin	Homo sapiens	26-37
4378052-2	1967	An adenosine triphosphatase system activated by sodium and potassium is present in high activity in the cochlear membranes (tegmentum vasculosum and stria vascularis).	Potassium	59-68	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	3-27
4228075-4	1967	As it is known that the ouabain-sensitive ATPase in fragmented ghosts requires both sodium and potassium ions, these results show that the ATPase is activated by potassium externally and by sodium internally, and suggest that the ions activating the ATPase are the ions that are transported.2.	Potassium	95-104	dynein axonemal heavy chain 8	Homo sapiens	42-48
4228075-4	1967	As it is known that the ouabain-sensitive ATPase in fragmented ghosts requires both sodium and potassium ions, these results show that the ATPase is activated by potassium externally and by sodium internally, and suggest that the ions activating the ATPase are the ions that are transported.2.	Potassium	95-104	dynein axonemal heavy chain 8	Homo sapiens	139-145
6076985-0	1967	[Participation of potassium in the tissue response to insulin].	Potassium	18-27	insulin	Homo sapiens	54-61
4228075-4	1967	As it is known that the ouabain-sensitive ATPase in fragmented ghosts requires both sodium and potassium ions, these results show that the ATPase is activated by potassium externally and by sodium internally, and suggest that the ions activating the ATPase are the ions that are transported.2.	Potassium	95-104	dynein axonemal heavy chain 8	Homo sapiens	139-145
4378052-4	1967	Since the microphonic potential depends on the high concentration of potassium ions in the endolymph, our findings strongly suggest the operation of an adenosine triphosphatase cation pump system activated by sodium and potassium, in the generation of cochlear cation gradients.	Potassium	69-78	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	152-176
4228075-4	1967	As it is known that the ouabain-sensitive ATPase in fragmented ghosts requires both sodium and potassium ions, these results show that the ATPase is activated by potassium externally and by sodium internally, and suggest that the ions activating the ATPase are the ions that are transported.2.	Potassium	162-171	dynein axonemal heavy chain 8	Homo sapiens	42-48
4378052-4	1967	Since the microphonic potential depends on the high concentration of potassium ions in the endolymph, our findings strongly suggest the operation of an adenosine triphosphatase cation pump system activated by sodium and potassium, in the generation of cochlear cation gradients.	Potassium	220-229	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	152-176
4228075-4	1967	As it is known that the ouabain-sensitive ATPase in fragmented ghosts requires both sodium and potassium ions, these results show that the ATPase is activated by potassium externally and by sodium internally, and suggest that the ions activating the ATPase are the ions that are transported.2.	Potassium	162-171	dynein axonemal heavy chain 8	Homo sapiens	139-145
4228075-4	1967	As it is known that the ouabain-sensitive ATPase in fragmented ghosts requires both sodium and potassium ions, these results show that the ATPase is activated by potassium externally and by sodium internally, and suggest that the ions activating the ATPase are the ions that are transported.2.	Potassium	162-171	dynein axonemal heavy chain 8	Homo sapiens	139-145
5286293-0	1967	[Inhibition of renin by potassium in the man].	Potassium	24-33	renin	Homo sapiens	15-20
6051802-8	1967	At 10 muM-[Na](o), potassium influx is half maximal at 0.14 mM-[K](o) and the curve is close to a rectangular hyperbola down to 22 muM-[K](o); there seems to be a trace of inflexion at about 15 muM-[K](o).4.	Potassium	19-28	latexin	Homo sapiens	6-9
6051802-8	1967	At 10 muM-[Na](o), potassium influx is half maximal at 0.14 mM-[K](o) and the curve is close to a rectangular hyperbola down to 22 muM-[K](o); there seems to be a trace of inflexion at about 15 muM-[K](o).4.	Potassium	19-28	latexin	Homo sapiens	131-134
6051802-8	1967	At 10 muM-[Na](o), potassium influx is half maximal at 0.14 mM-[K](o) and the curve is close to a rectangular hyperbola down to 22 muM-[K](o); there seems to be a trace of inflexion at about 15 muM-[K](o).4.	Potassium	19-28	latexin	Homo sapiens	131-134
6017996-0	1967	Insulin effects on gastric secretion and blood electrolytes modified by injected potassium.	Potassium	81-90	insulin	Homo sapiens	0-7
6034114-9	1967	During secretin stimulation the sodium concentration in pancreatic tissue increases, and the potassium concentration falls.4.	Potassium	93-102	secretin	Homo sapiens	7-15
6057515-0	1967	[Inhibition of plasmatic renin activity by potassium].	Potassium	43-52	renin	Homo sapiens	25-30
5610046-0	1967	[Increase in the sensitivity of afferent fibers to the stimulating action of potassium ions induced by bradykinin.	Potassium	77-86	kininogen 1	Homo sapiens	103-113
4288511-0	1966	[Sodium-potassium quotient during ACTH administration--a simple function test of the adrenal cortex].	Potassium	8-17	proopiomelanocortin	Homo sapiens	34-38
6023776-5	1967	Concomitant measurements of endogenous creatinine clearance and the rates of excretion of sodium and potassium suggest that a fall in renal arterial perfusion resulting from upright posture induces increased release of renin and the subsequent secondary stimulation of aldosterone secretion.	Potassium	101-110	renin	Homo sapiens	219-224
4296201-2	1967	Relationship of ATP-ase to the active transport of sodium and potassium ions.	Potassium	62-71	dynein axonemal heavy chain 8	Homo sapiens	16-23
4872261-0	1967	[Inhibition of renin by potassium in humans].	Potassium	24-33	renin	Homo sapiens	15-20
4223577-0	1966	Separation of adenosine diphosphate--adenosine triphosphate-exchange activity from the cerebral microsomal sodium-plus-potassium ion-stimulated adenosine triphosphatase.	Potassium	119-128	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	144-168
5967742-0	1966	Potassium content of the vitreous body as an aid in determining the time of death.	Potassium	0-9	activation induced cytidine deaminase	Homo sapiens	45-48
5923064-0	1966	Relation between toad bladder potassium content and permeability response to vasopressin.	Potassium	30-39	arginine vasopressin	Homo sapiens	77-88
4229837-0	1966	[The effect of insulin on the transport of potassium in skeletal muscles].	Potassium	43-52	insulin	Homo sapiens	15-22
4380024-0	1966	The effect of thiols and ganglioside on the alterations in water, sodium and potassium distribution produced in brain slices by vasopressin and protamine.	Potassium	77-86	arginine vasopressin	Homo sapiens	128-139
4952748-0	1966	Reversal of insulin inhibition of gastric secretion by intravenous injection of potassium.	Potassium	80-89	insulin	Homo sapiens	12-19
5912660-0	1966	Potassium, sodium, and chlorides in gastrin-stimulated gastric secretion in man.	Potassium	0-9	gastrin	Homo sapiens	36-43
4225829-0	1966	Studies on the activity of sodium and potassium activated ATP-ase in normal and leukemic granulocytes.	Potassium	38-47	dynein axonemal heavy chain 8	Homo sapiens	58-65
5888830-0	1965	[Studies on potassium distribution and determination of total body potassium by measurement of K40].	Potassium	67-76	keratin 40	Homo sapiens	95-98
14163532-0	1964	SPECIES DIFFERENCES IN THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE ATPASE OF ERYTHROCYTE MEMBRANES.	Potassium	48-57	dynein axonemal heavy chain 8	Homo sapiens	70-76
14284777-13	1965	However, with sulfate as anion, vasopressin elicited an increase in short-circuit current and/or in cell volume despite high internal potassium concentrations.	Potassium	134-143	arginine vasopressin	Homo sapiens	32-43
14202192-0	1964	THE EFFECTS OF OSMOTIC DIURESIS AND VASOPRESSIN UPON THE DISTRIBUTION OF SODIUM, POTASSIUM AND UREA IN THE RAT KIDNEY.	Potassium	81-90	arginine vasopressin	Rattus norvegicus	36-47
17752020-2	1963	The b-axis length of Silversheen mica (a 2M(1) muscovite) decreases from 9.024 to 8.988 A as the potassium content decreases from 8.79 to 3.31 percent.	Potassium	97-106	MHC class I polypeptide-related sequence A	Homo sapiens	33-37
14020469-0	1963	The action of insulin on the blood potassium and phosphate in endocrine disorders.	Potassium	35-44	insulin	Homo sapiens	14-21
13969508-0	1962	[Action of different inhibitors of L-DOPA decarboxylase on the water ration, diuresis and urinary sodium and potassium elimination in rats].	Potassium	109-118	dopa decarboxylase	Rattus norvegicus	35-55
13964352-0	1962	The effect of insulin on gastric secretion of potassium.	Potassium	46-55	insulin	Homo sapiens	14-21
14478163-0	1961	Experimental studies of the electrocardiographic effect of potassium solution on a toad"s heart in the presence of insulin and glucose.	Potassium	59-68	insulin	Homo sapiens	115-122
14006658-0	1961	The sensitivity of a kidney ATPase to ouabain and to sodium and potassium.	Potassium	64-73	dynein axonemal heavy chain 8	Homo sapiens	28-34
14472695-0	1961	[Relation between potassium and insulin effect in the isolated muscle].	Potassium	18-27	insulin	Homo sapiens	32-39
14450728-0	1961	The effect of insulin on gastric secretion of potassium.	Potassium	46-55	insulin	Homo sapiens	14-21
13696676-0	1961	[Action of oxytocin on the renal excretion of water, sodium and potassium].	Potassium	64-73	oxytocin/neurophysin I prepropeptide	Homo sapiens	11-19
13695136-0	1961	Potassium content of rat diaphragms following hypophysectomy and incubation with growth hormone.	Potassium	0-9	gonadotropin releasing hormone receptor	Rattus norvegicus	81-95
13765462-0	1961	A determination of Ks, the substrate constant, for serum cholinesterase.	Potassium	19-21	butyrylcholinesterase	Homo sapiens	57-71
14411767-0	1960	[Depolarization and potassium liberation from mammal muscle under the influence of decamethonium bromide (C 10)].	Potassium	20-29	homeobox C10	Homo sapiens	106-110
13774985-0	1961	[Studies on the influence of potassium concentration on the interaction between actomyosin and ATP].	Potassium	29-38	ATPase phospholipid transporting 8A2	Homo sapiens	95-99
16655429-0	1960	Accumulation of Potassium, Cesium, and Rubidium in Bean Plants Grown in Nutrient Solutions.	Potassium	16-25	brain expressed associated with NEDD4 1	Homo sapiens	51-55
13641422-0	1959	Potassium transport in the acetylcholinesterase-deficient erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH).	Potassium	0-9	acetylcholinesterase (Cartwright blood group)	Homo sapiens	27-47
14411379-0	1959	The effects of an intracarotid injection of hyperosmotic NaC1 solutions on water, sodium and potassium excretion in the human being.	Potassium	93-102	nucleus accumbens associated 1	Homo sapiens	57-61
14411313-0	1959	[Electrophysiological studies on the suppression of potassium paralysis of frog myocardium by ATP].	Potassium	52-61	ATPase phospholipid transporting 8A2	Homo sapiens	94-98
13622140-0	1959	[Potassium permanganate reaction in CSF].	Potassium	1-10	colony stimulating factor 2	Homo sapiens	36-39
13652970-0	1959	Effect of insulin on potassium transfer in human and chicken erythrocytes.	Potassium	21-30	insulin	Homo sapiens	10-17
14444912-0	1959	[The influence of potassium deficiency on the antidiuretic effect of vasopressin].	Potassium	18-27	arginine vasopressin	Homo sapiens	69-80
13550246-0	1958	The relation of potassium deficiency to muscular paralysis by insulin.	Potassium	16-25	insulin	Homo sapiens	62-69
13607824-0	1958	[Effect of insulin on plasma sodium and potassium in pigeons].	Potassium	40-49	insulin	Homo sapiens	11-18
13483699-0	1957	[In vitro studies on relation between potassium deficiency, muscular paralysis &amp; insulin].	Potassium	38-47	insulin	Homo sapiens	85-92
13594540-0	1958	The effect of potassium ions and glutamate on the incorporation of P-32 into nucleotides and phosphocreatine in brain slices.	Potassium	14-23	inhibitor of growth family member 2	Homo sapiens	67-71
13561335-0	1958	[Effect of vasopressin on the elimination of water load, sodium and potassium in weanling rats].	Potassium	68-77	arginine vasopressin	Rattus norvegicus	11-22
13563565-2	1958	The division of cell potassium into two fractions during incubation with 0.025 M NaF.	Potassium	21-30	C-X-C motif chemokine ligand 8	Homo sapiens	81-84
13420525-0	1956	[Determination of potassium ions in total blood, serum and CSF in mental diseases with flame electrophoresis].	Potassium	18-27	colony stimulating factor 2	Homo sapiens	59-62
13364718-0	1956	The potassium uptake and rate of oxygen consumption of isolated frog skeletal muscle in the presence of insulin and lactate.	Potassium	4-13	insulin	Homo sapiens	104-111
13448105-0	1957	[Study of clinical aspects and water, sodium and potassium excretion during treatment with ACTH, cortisone and related compounds].	Potassium	49-58	proopiomelanocortin	Homo sapiens	91-95
13228659-0	1955	Effect of in vivo inhibition of cholinesterase on potassium diffusion from the human red cell.	Potassium	50-59	butyrylcholinesterase	Homo sapiens	32-46
13250751-0	1955	[The potassium load curve and experimental modifications induced in children with Heine-Medin disease].	Potassium	5-14	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	88-93
13220520-0	1955	Role of potassium in the protein-catabolic effect of cortisone and ACTH.	Potassium	8-17	proopiomelanocortin	Homo sapiens	67-71
13250792-0	1955	[Variations of plasma sodium, potassium and magnesium under the effect of insulin].	Potassium	30-39	insulin	Homo sapiens	74-81
13239582-0	1955	On the mechanism of the potassium loss from brain slices induced by cholinesterase inhibitors.	Potassium	24-33	butyrylcholinesterase	Homo sapiens	68-82
13115688-0	1954	POST-OPERATIVE potassium deficiency.	Potassium	15-24	solute carrier family 35 member G1	Homo sapiens	0-4
13208610-0	1954	The effect of cholinesterase inhibitors on the leakage of potassium from brain slices.	Potassium	58-67	butyrylcholinesterase	Homo sapiens	14-28
13168421-0	1954	[Clinical study of the renal tubular reabsorption of potassium and sodium under the influence of ACTH and cortisone in normal man].	Potassium	53-62	proopiomelanocortin	Homo sapiens	97-101
13086766-0	1953	[Insulin hypoglycemia as element of different serum-erythrocyte distributions of potassium and sodium].	Potassium	81-90	insulin	Homo sapiens	1-8
13107633-0	1953	Mechanisms of insulin and epinephrine effect on the level of plasma potassium.	Potassium	68-77	insulin	Homo sapiens	14-21
13181026-0	1954	[Clinical study of renal tubular resorption of potassium and sodium under the action of ACTH and cortisone.	Potassium	47-56	proopiomelanocortin	Homo sapiens	88-92
13090101-0	1953	[Potassium in deficiency prevention in ACTH and cortisone therapy].	Potassium	1-10	proopiomelanocortin	Homo sapiens	39-43
13124845-0	1953	[Effect of potassium on secretion of ACTH; role of corticosteroids].	Potassium	11-20	proopiomelanocortin	Homo sapiens	37-41
13148681-0	1953	[Effect of potassium on ACTH secretion; role of corticosteroids].	Potassium	11-20	proopiomelanocortin	Homo sapiens	24-28
13031658-2	1953	Replacement of potassium in erythrocytes during cholinesterase activity.	Potassium	15-24	butyrylcholinesterase	Homo sapiens	48-62
13052669-0	1953	Does a large intake of potassium modify the metabolic effects of ACTH in man?	Potassium	23-32	proopiomelanocortin	Homo sapiens	65-69
13055983-0	1953	Epinephrine and insulin effect on potassium mobilization; relationship of lipid and carbohydrate metabolism.	Potassium	34-43	insulin	Homo sapiens	16-23
14927720-0	1952	The influence of ACTH on the sodium and potassium concentration of human mixed saliva.	Potassium	40-49	proopiomelanocortin	Homo sapiens	17-21
13208668-0	1952	[The role of magnesium and potassium in the reaction of fructokinase].	Potassium	27-36	ketohexokinase	Homo sapiens	56-68
13016806-0	1952	Sodium, potassium and chloride retention produced by growth hormone in the absence of the adrenals.	Potassium	8-17	growth hormone 1	Homo sapiens	53-67
14958479-0	1952	The electrocardiographic and plasma potassium changes after adrenalin and insulin injections.	Potassium	36-45	insulin	Homo sapiens	74-81
14911014-0	1952	Body potassium loss during therapy with ACTH and cortisone.	Potassium	5-14	proopiomelanocortin	Homo sapiens	40-44
14914876-0	1952	Effect of cholinesterase and choline acetylase inhibitors on the potassium concentration gradient and potassium exchange of human erythrocytes.	Potassium	65-74	choline O-acetyltransferase	Homo sapiens	29-46
14914876-0	1952	Effect of cholinesterase and choline acetylase inhibitors on the potassium concentration gradient and potassium exchange of human erythrocytes.	Potassium	102-111	butyrylcholinesterase	Homo sapiens	10-24
14914876-0	1952	Effect of cholinesterase and choline acetylase inhibitors on the potassium concentration gradient and potassium exchange of human erythrocytes.	Potassium	102-111	choline O-acetyltransferase	Homo sapiens	29-46
14917842-0	1952	The effect of ACTH and cortisone on the sodium and potassium levels of human saliva.	Potassium	51-60	proopiomelanocortin	Homo sapiens	14-18
14920503-0	1952	Reduction of urinary sodium and potassium produced by hypophyseal growth hormone in normal female rats.	Potassium	32-41	gonadotropin releasing hormone receptor	Rattus norvegicus	66-80
14914876-0	1952	Effect of cholinesterase and choline acetylase inhibitors on the potassium concentration gradient and potassium exchange of human erythrocytes.	Potassium	65-74	butyrylcholinesterase	Homo sapiens	10-24
14906298-0	1951	The effect of epinephrine and insulin on the plasma potassium level.	Potassium	52-61	insulin	Homo sapiens	30-37
14866879-0	1951	Potassium, sodium, water content and adenosinetriphosphatase activity of vas deferens from normal and castrated rats.	Potassium	0-9	arginine vasopressin	Rattus norvegicus	73-76
14864646-0	1951	Reduction of urinary sodium and potassium of diabetic rats produced by hypophyseal growth hormone.	Potassium	32-41	gonadotropin releasing hormone receptor	Rattus norvegicus	83-97
14857892-0	1951	The influence of glucose and insulin upon the potassium concentration of serum and cerebrospinal fluid.	Potassium	46-55	insulin	Homo sapiens	29-36
19872878-5	1935	The treatment with distilled water which removes the potassium effect from the outer protoplasmic surface does not seem to affect the inner protoplasmic surface in the same way since the latter retains the outwardly directed potential which is apparently due to the potassium in the sap.	Potassium	266-275	SH2 domain containing 1A	Homo sapiens	283-286
14795066-0	1950	The effects of sodium and potassium on the metabolic and physiologic responses to ACTH.	Potassium	26-35	proopiomelanocortin	Homo sapiens	82-86
19873117-14	1939	As in previous experiments, the entering ammonia displaced a practically equivalent amount of potassium from the sap and the sodium concentration remained fairly constant.	Potassium	94-103	SH2 domain containing 1A	Homo sapiens	113-116
14791434-0	1950	The influence of carbohydrates and insulin on the potassium content of leucocytes and muscle.	Potassium	50-59	insulin	Homo sapiens	35-42
19872836-4	1934	Potassium passes from the external solution through the non-aqueous layer into the artificial sap and there reacts with CO(2) to form KHCO(3): its rate of entrance depends on the supply of CO(2).	Potassium	0-9	SH2 domain containing 1A	Homo sapiens	94-97
19872676-9	1932	Potassium penetrates by combining with an acid HX in the non-aqueous layer to form KX which in turn reacts with an acid HA in the sap to form KA.	Potassium	0-9	SH2 domain containing 1A	Homo sapiens	130-133
19872676-12	1932	The internal composition depends on permeability, e.g., sodium penetrates less rapidly than potassium and in consequence potassium predominates over sodium in the "artificial sap."	Potassium	121-130	SH2 domain containing 1A	Homo sapiens	175-178
19872627-7	1931	(21) have shown that potassium and phosphorus of the blood are decreased and Luck, Morrison, and Wilbur (22) indicate a reduction in the amino acids of the blood in insulin treatment.	Potassium	21-30	insulin	Bos taurus	165-172
19872836-6	1934	By regulating the supply of CO(2) and the osmotic pressure we are able to keep the volume and composition of the artificial sap approximately constant while maintaining a higher concentration of potassium than in the external solution.	Potassium	195-204	SH2 domain containing 1A	Homo sapiens	124-127
19872792-21	1934	Since CO(2) and HCO(3) (-) diffuse into A and combine with KG and NaG the inward movement of potassium and sodium falls off in proportion as the concentration of KG and NaG is lessened.	Potassium	93-102	NBAS subunit of NRZ tethering complex	Homo sapiens	59-69
19872792-21	1934	Since CO(2) and HCO(3) (-) diffuse into A and combine with KG and NaG the inward movement of potassium and sodium falls off in proportion as the concentration of KG and NaG is lessened.	Potassium	93-102	NBAS subunit of NRZ tethering complex	Homo sapiens	66-69
33992895-7	2021	The values of the binding constants were KS(PTP1B-PB1) = 4.06 x 102 L mol-1 and KS(PTP1B-PB2) = 2.53 x 102 L mol-1, indicating that the binding affinity of PTP1B to PB1 was higher than that for PB2.	Potassium	41-43	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	44-49
33992895-7	2021	The values of the binding constants were KS(PTP1B-PB1) = 4.06 x 102 L mol-1 and KS(PTP1B-PB2) = 2.53 x 102 L mol-1, indicating that the binding affinity of PTP1B to PB1 was higher than that for PB2.	Potassium	41-43	polybromo 1	Homo sapiens	50-53
33992895-7	2021	The values of the binding constants were KS(PTP1B-PB1) = 4.06 x 102 L mol-1 and KS(PTP1B-PB2) = 2.53 x 102 L mol-1, indicating that the binding affinity of PTP1B to PB1 was higher than that for PB2.	Potassium	41-43	polybromo 1	Homo sapiens	165-168
33992895-7	2021	The values of the binding constants were KS(PTP1B-PB1) = 4.06 x 102 L mol-1 and KS(PTP1B-PB2) = 2.53 x 102 L mol-1, indicating that the binding affinity of PTP1B to PB1 was higher than that for PB2.	Potassium	80-82	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	83-88
33992895-7	2021	The values of the binding constants were KS(PTP1B-PB1) = 4.06 x 102 L mol-1 and KS(PTP1B-PB2) = 2.53 x 102 L mol-1, indicating that the binding affinity of PTP1B to PB1 was higher than that for PB2.	Potassium	80-82	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	83-88
33992895-7	2021	The values of the binding constants were KS(PTP1B-PB1) = 4.06 x 102 L mol-1 and KS(PTP1B-PB2) = 2.53 x 102 L mol-1, indicating that the binding affinity of PTP1B to PB1 was higher than that for PB2.	Potassium	80-82	polybromo 1	Homo sapiens	165-168
33861146-11	2021	Potassium levels were also associated with insulin-mediated reductions in AP (r=0.52, P=0.002).	Potassium	0-9	insulin	Homo sapiens	43-50
33978701-8	2021	Remarkably, whole-cell patch-clamp recording demonstrated that risperidone acutely inhibited the activity of hypothalamic Mc4r neurons via the opening of a postsynaptic potassium conductance.	Potassium	169-178	melanocortin 4 receptor	Mus musculus	122-126
33968186-5	2021	The present review aimed to determine whether activated CaMKII induces early afterdepolarizations and delayed afterdepolarizations that result in VA by regulating sodium, potassium and calcium ions.	Potassium	171-180	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	56-62
33839521-0	2021	Immunomodulatory and protective effects of interleukin-4 on the neuropathological alterations induced by a potassium channel blocker.	Potassium	107-116	interleukin 4	Mus musculus	43-56
33667541-1	2021	It is well-established that extracellular potassium (Ko+) accumulation reduces muscle fiber excitability, however the effects of Ko+ on the excitation-contraction coupling (ECC) pathway are less understood.	Potassium	42-51	keratin 8	Homo sapiens	53-55
33866617-3	2021	Research in male rodents has shown that activation of PAR2 can produce peripheral vasodilation, stimulate renal sodium chloride reabsorption, and inhibit renal potassium secretion.	Potassium	160-169	F2R like trypsin receptor 1	Rattus norvegicus	54-58
33866617-10	2021	Research in male rodents has shown that activation of PAR2 can produce peripheral vasodilation, stimulate renal sodium chloride reabsorption, and inhibit renal potassium secretion.	Potassium	160-169	F2R like trypsin receptor 1	Rattus norvegicus	54-58
33280043-0	2021	Title: Effect of increased potassium intake on the renin-angiotensin-aldosterone system and subcutaneous resistance arteries: a randomized crossover study.	Potassium	27-36	renin	Homo sapiens	51-56
33050826-2	2021	Functional hyperemia depends on capillary endothelial cell inward rectifier potassium channels (Kir2.1) responding to potassium (K+) released during neuronal activity to produce a regenerative, hyperpolarizing electrical signal that propagates from capillaries to dilate upstream penetrating arterioles.	Potassium	76-85	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	96-102
34047430-6	2021	We characterized whole-cell potassium and sodium currents, both involved in action potential (AP) shaping and propagation and determined NO-mediated changes in excitabilities and AP waveforms.	Potassium	28-37	LIM homeobox protein 2	Mus musculus	94-96
34047430-7	2021	Our data describe a novel signaling by which NO, in a cGMP-independent manner, suppresses voltage-gated Kv2 potassium and voltage-gated sodium channel activities, thereby widening AP waveforms and reducing depolarization-induced AP firing rates.	Potassium	108-117	LIM homeobox protein 2	Mus musculus	180-182
34047430-7	2021	Our data describe a novel signaling by which NO, in a cGMP-independent manner, suppresses voltage-gated Kv2 potassium and voltage-gated sodium channel activities, thereby widening AP waveforms and reducing depolarization-induced AP firing rates.	Potassium	108-117	LIM homeobox protein 2	Mus musculus	229-231
34052311-7	2021	In potassium-free buffer, LDL(-)-induced IL-1beta reached a level similar to that induced by cotreatment with LDL(-) and PA-BSA.	Potassium	3-12	interleukin 1 alpha	Homo sapiens	41-49
33993515-0	2021	Reduced Alternative Insulin Dosing in Hyperkalemia: a Meta-Analysis of Effects on Hypoglycemia and Potassium Reduction.	Potassium	99-108	insulin	Homo sapiens	20-27
34038119-2	2021	Our first disclosed clinical ROMK compound, 2 (MK-7145), demonstrated robust diuresis, natriuresis, and blood pressure lowering in preclinical models, with reduced urinary potassium excretion compared to the standard of care diuretics.	Potassium	172-181	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	29-33
33909591-7	2021	The deletion was 1.8 Mb upstream of a KS candidate gene locus (PALM2AKAP2), but did not suppress its expression.	Potassium	38-40	PALM2 and AKAP2 fusion	Homo sapiens	63-73
34013341-4	2021	PURPOSE: To provide evidence of serum potassium changes in individuals taking angiotensin-converting enzyme inhibitors (ACEIs) and/or angiotensin receptor blockers (ARBs) concomitantly with spironolactone compared to ACEI/ARB therapy alone.	Potassium	38-47	angiotensin I converting enzyme	Homo sapiens	78-107
34029145-6	2021	Renal clearance experiments showed that HK-intake decreased while LK intake increased hydrochlorothiazide (HCTZ)-induced renal Na+ excretion only in the control mice but this effect was absent in Ks-Nedd4-2 KO mice.	Potassium	196-198	neural precursor cell expressed, developmentally down-regulated 4	Mus musculus	199-204
34029145-8	2021	Furthermore, the expression of all three subunits of epithelia-Na+-channel (ENaC) in the Ks-Nedd4-2 KO mice on HK was higher than in the control mice.	Potassium	89-91	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	53-74
34029145-8	2021	Furthermore, the expression of all three subunits of epithelia-Na+-channel (ENaC) in the Ks-Nedd4-2 KO mice on HK was higher than in the control mice.	Potassium	89-91	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	76-80
34029145-8	2021	Furthermore, the expression of all three subunits of epithelia-Na+-channel (ENaC) in the Ks-Nedd4-2 KO mice on HK was higher than in the control mice.	Potassium	89-91	neural precursor cell expressed, developmentally down-regulated 4	Mus musculus	92-97
33993515-3	2021	This meta-analysis was performed to determine the impact of alternative insulin dosing on hypoglycemia and potassium reduction in patients with hyperkalemia.	Potassium	107-116	insulin	Homo sapiens	72-79
33993515-11	2021	CONCLUSIONS: Alternative insulin dosing strategies for hyperkalemia management resulted in less hypoglycemia and severe hypoglycemia without compromising potassium reduction compared to standard dose.	Potassium	154-163	insulin	Homo sapiens	25-32
33990773-6	2021	NRG1 and ErbB4 suppressed potassium currents of VTA DA neurons and increased their firing activity.	Potassium	26-35	neuregulin 1	Mus musculus	0-4
33990773-6	2021	NRG1 and ErbB4 suppressed potassium currents of VTA DA neurons and increased their firing activity.	Potassium	26-35	erb-b2 receptor tyrosine kinase 4	Mus musculus	9-14
33960280-4	2021	Comprehensive ophthalmic examinations, however, guided the diagnosis of CDSRR from a novel mutation in potassium voltage-gated channel modifier subfamily V member 2 (KCNV2) gene.Materials and methods: Comprehensive ophthalmic examinations were evaluated for two patients whose parents are first cousins.	Potassium	103-112	potassium voltage-gated channel modifier subfamily V member 2	Homo sapiens	166-171
33978965-6	2021	The comparison of the molecular structures of two closely related potassium silolides provided an example for different coordination of the potassium cation to the silolyl anion (eta 1 vs. eta 5 coordination) that triggers the switch between delocalized and localized states.	Potassium	66-75	secreted phosphoprotein 1	Homo sapiens	179-184
34054566-2	2021	The renal outer medullary potassium (ROMK) channel accounts for the major K+ secretory route in collecting ducts during basal conditions.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	37-41
34025388-9	2021	Age-related CAPD subjects had a lower intake of potassium, vitamin C, and a higher fat intake.	Potassium	48-57	renin binding protein	Homo sapiens	0-3
33870711-7	2021	In contrast, the hemodynamic responses (blood pressure, total peripheral resistance, cardiac output, and renal artery blood flow) to AngII were similar after potassium and placebo.	Potassium	158-167	angiotensinogen	Homo sapiens	133-138
33870711-0	2021	Effect of Increased Potassium Intake on Adrenal Cortical and Cardiovascular Responses to Angiotensin II: A Randomized Crossover Study.	Potassium	20-29	angiotensinogen	Homo sapiens	89-103
33870711-6	2021	The study showed that higher potassium intake increased plasma potassium (mean+-SD, 4.3+-0.2 versus 4.0+-0.2 mmol/L; P=0.0002) and aldosterone (median [interquartile range], 440 [336-521] versus 237 [173-386] pmol/L; P<0.0001), and based on a linear mixed model for repeated measurements, increased potassium intake potentiated AngII-stimulated aldosterone secretion (P=0.0020).	Potassium	29-38	angiotensinogen	Homo sapiens	328-333
34017331-8	2021	Moreover, this process of SEO+ATP-induced IL-1beta secretion was dependent on potassium (K+) efflux.	Potassium	78-87	interleukin 1 alpha	Mus musculus	42-50
33870711-8	2021	Conclusions Increased potassium intake potentiates AngII-stimulated aldosterone secretion without affecting systemic cardiovascular hemodynamics in healthy normotensive men.	Potassium	22-31	angiotensinogen	Homo sapiens	51-56
33682442-3	2021	It has recently been shown that a less severe form of the Familial Hyperkalemic Hypertension featuring only hyperkalemia is caused by missense mutations in the WNK1 acidic domain that preferentially affect CUL3-KLHL3 E3-induced degradation of KS-WNK1, rather than that of the full-length WNK1 (L-WNK1).	Potassium	243-245	WNK lysine deficient protein kinase 1	Mus musculus	160-164
33439774-5	2021	We therefore investigated whether potassium regulates WNK activity independent of chloride.	Potassium	34-43	Wnk kinase	Drosophila melanogaster	54-57
33439774-6	2021	We found decreased activity of Drosophila WNK and mammalian WNK3 and WNK4 in fly Malpighian (renal) tubules bathed in high extracellular potassium, even when intracellular chloride was kept constant at either ~13 mM or 26 mM.	Potassium	137-146	Wnk kinase	Drosophila melanogaster	42-45
33439774-6	2021	We found decreased activity of Drosophila WNK and mammalian WNK3 and WNK4 in fly Malpighian (renal) tubules bathed in high extracellular potassium, even when intracellular chloride was kept constant at either ~13 mM or 26 mM.	Potassium	137-146	WNK lysine deficient protein kinase 3	Homo sapiens	60-64
33439774-6	2021	We found decreased activity of Drosophila WNK and mammalian WNK3 and WNK4 in fly Malpighian (renal) tubules bathed in high extracellular potassium, even when intracellular chloride was kept constant at either ~13 mM or 26 mM.	Potassium	137-146	WNK lysine deficient protein kinase 4	Homo sapiens	69-73
33439774-7	2021	High extracellular potassium also inhibited chloride-insensitive mutants of WNK3 and WNK4.	Potassium	19-28	WNK lysine deficient protein kinase 3	Homo sapiens	76-80
33439774-7	2021	High extracellular potassium also inhibited chloride-insensitive mutants of WNK3 and WNK4.	Potassium	19-28	WNK lysine deficient protein kinase 4	Homo sapiens	85-89
33682442-3	2021	It has recently been shown that a less severe form of the Familial Hyperkalemic Hypertension featuring only hyperkalemia is caused by missense mutations in the WNK1 acidic domain that preferentially affect CUL3-KLHL3 E3-induced degradation of KS-WNK1, rather than that of the full-length WNK1 (L-WNK1).	Potassium	243-245	cullin 3	Mus musculus	206-210
33439774-9	2021	The Na+/K+-ATPase inhibitor, ouabain, which is expected to lower intracellular potassium, increased tubule Drosophila WNK activity.	Potassium	79-88	Wnk kinase	Drosophila melanogaster	118-121
33439774-10	2021	In vitro, potassium increased the melting temperature of Drosophila WNK, WNK1 and WNK3 kinase domains, indicating ion binding to the kinase.	Potassium	10-19	Wnk kinase	Drosophila melanogaster	68-71
33439774-10	2021	In vitro, potassium increased the melting temperature of Drosophila WNK, WNK1 and WNK3 kinase domains, indicating ion binding to the kinase.	Potassium	10-19	WNK lysine deficient protein kinase 3	Homo sapiens	82-86
33749322-11	2021	Together these data indicate that AQP2 regulation is disrupted by a small decrease in PK and the response is influenced by sexual dimorphism in potassium handling.	Potassium	144-153	aquaporin 2	Mus musculus	34-38
33439774-11	2021	Potassium inhibited in vitro autophosphorylation of Drosophila WNK and WNK3, and also inhibited WNK3 and WNK4 phosphorylation of their substrate, SPAK (Ste20-related proline/alanine-rich kinase).	Potassium	0-9	Wnk kinase	Drosophila melanogaster	63-66
33439774-11	2021	Potassium inhibited in vitro autophosphorylation of Drosophila WNK and WNK3, and also inhibited WNK3 and WNK4 phosphorylation of their substrate, SPAK (Ste20-related proline/alanine-rich kinase).	Potassium	0-9	WNK lysine deficient protein kinase 3	Homo sapiens	71-75
33439774-11	2021	Potassium inhibited in vitro autophosphorylation of Drosophila WNK and WNK3, and also inhibited WNK3 and WNK4 phosphorylation of their substrate, SPAK (Ste20-related proline/alanine-rich kinase).	Potassium	0-9	WNK lysine deficient protein kinase 3	Homo sapiens	96-100
33439774-11	2021	Potassium inhibited in vitro autophosphorylation of Drosophila WNK and WNK3, and also inhibited WNK3 and WNK4 phosphorylation of their substrate, SPAK (Ste20-related proline/alanine-rich kinase).	Potassium	0-9	WNK lysine deficient protein kinase 4	Homo sapiens	105-109
33439774-11	2021	Potassium inhibited in vitro autophosphorylation of Drosophila WNK and WNK3, and also inhibited WNK3 and WNK4 phosphorylation of their substrate, SPAK (Ste20-related proline/alanine-rich kinase).	Potassium	0-9	mushroom bodies tiny	Drosophila melanogaster	152-157
33439774-12	2021	The greatest sensitivity of WNK4 to potassium occurred in the range of 80 to 180 mM, encompassing physiological intracellular potassium concentrations.	Potassium	36-45	WNK lysine deficient protein kinase 4	Homo sapiens	28-32
33439774-12	2021	The greatest sensitivity of WNK4 to potassium occurred in the range of 80 to 180 mM, encompassing physiological intracellular potassium concentrations.	Potassium	126-135	WNK lysine deficient protein kinase 4	Homo sapiens	28-32
33439774-13	2021	Together, these data indicate chloride-independent potassium inhibition of Drosophila and mammalian WNK kinases through direct effects of potassium ion on the kinase.	Potassium	51-60	Wnk kinase	Drosophila melanogaster	100-103
33439774-13	2021	Together, these data indicate chloride-independent potassium inhibition of Drosophila and mammalian WNK kinases through direct effects of potassium ion on the kinase.	Potassium	138-147	Wnk kinase	Drosophila melanogaster	100-103
33934480-12	2021	CONCLUSION: pH-adjusted potassium (pHK ) shall be used as a marker for hypokalemia and to initiate potassium replacement instead of measure serum potassium in DKA.	Potassium	24-33	phosphorylase kinase regulatory subunit alpha 2	Homo sapiens	35-38
33934480-12	2021	CONCLUSION: pH-adjusted potassium (pHK ) shall be used as a marker for hypokalemia and to initiate potassium replacement instead of measure serum potassium in DKA.	Potassium	99-108	phosphorylase kinase regulatory subunit alpha 2	Homo sapiens	35-38
33934480-12	2021	CONCLUSION: pH-adjusted potassium (pHK ) shall be used as a marker for hypokalemia and to initiate potassium replacement instead of measure serum potassium in DKA.	Potassium	99-108	phosphorylase kinase regulatory subunit alpha 2	Homo sapiens	35-38
33423833-8	2021	Redistribution of potassium ions from the bloodstream into the cells is based on intravenous insulin or nebulized beta2-agonists.	Potassium	18-27	insulin	Homo sapiens	93-100
33388987-1	2021	PURPOSE: To determine patients with abnormal sensation in the throat (AST) who would respond to potassium-competitive acid blocker (P-CAB) or serotonin noradrenaline reuptake inhibitor (SNRI) treatment.	Potassium	96-105	neural proliferation, differentiation and control 1	Homo sapiens	134-137
33581123-4	2021	IL-4-stimulated eotaxin-3 secretion was measured by ELISA after treatment with omeprazole, SCH 28080 (potassium-competitive acid blocker), EGTA-AM (calcium chelator), 2-APB (inhibitor of endoplasmic reticulum calcium release), verapamil and diltiazem (L-type calcium channel inhibitors).	Potassium	102-111	interleukin 4	Homo sapiens	0-4
33581123-4	2021	IL-4-stimulated eotaxin-3 secretion was measured by ELISA after treatment with omeprazole, SCH 28080 (potassium-competitive acid blocker), EGTA-AM (calcium chelator), 2-APB (inhibitor of endoplasmic reticulum calcium release), verapamil and diltiazem (L-type calcium channel inhibitors).	Potassium	102-111	C-C motif chemokine ligand 26	Homo sapiens	16-25
33705345-4	2021	Supplementation of potassium inhibited the effect of aldosterone on the Rhcg.	Potassium	19-28	Rhesus blood group-associated C glycoprotein	Mus musculus	72-76
33705345-13	2021	These results suggest that aldosterone regulates the membrane expression of Rhcg through the mineralocorticoid receptor and PKC pathways, which is modulated by extracellular potassium level.	Potassium	174-183	Rhesus blood group-associated C glycoprotein	Mus musculus	76-80
33423833-8	2021	Redistribution of potassium ions from the bloodstream into the cells is based on intravenous insulin or nebulized beta2-agonists.	Potassium	18-27	ATPase H+ transporting V0 subunit a2	Homo sapiens	114-119
33336302-3	2021	Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the potassium ion channel KV7.4 (KCNQ4) in outer hair cells, inspiring future therapies to maintain or prevent the decline of potassium ion channel surface expression to reduce ARHL.	Potassium	140-149	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	162-167
33411244-6	2021	The non-edited Kv1.1 overexpression led to slight elevations in both fast- and non-inactivating current components of macroscopic potassium current.	Potassium	130-139	potassium voltage-gated channel subfamily A member 1	Homo sapiens	15-20
33657579-0	2021	Effect of potassium on DNA methylation of aldosterone synthase gene.	Potassium	10-19	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	42-62
33657579-1	2021	BACKGROUND: Aldosterone synthase gene, CYP11B2 is regulated by potassium and angiotensin II (Ang II).	Potassium	63-72	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	12-32
33657579-1	2021	BACKGROUND: Aldosterone synthase gene, CYP11B2 is regulated by potassium and angiotensin II (Ang II).	Potassium	63-72	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	39-46
33657579-3	2021	Similar to Ang II, small increases in extracellular potassium levels also increase CYP11B2 mRNA levels.	Potassium	52-61	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	83-90
33336302-3	2021	Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the potassium ion channel KV7.4 (KCNQ4) in outer hair cells, inspiring future therapies to maintain or prevent the decline of potassium ion channel surface expression to reduce ARHL.	Potassium	140-149	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	169-174
33004259-3	2021	Recent work revealed that HBL binds to the mammalian surface receptors LITAF and CDIP1 and that both HBL and NHE induce potassium efflux and activate the NLRP3 inflammasome, leading to pyroptosis.	Potassium	120-129	NLR family pyrin domain containing 3	Homo sapiens	154-159
33657579-8	2021	Potassium stimulation caused DNA demethylation around cyclic AMP responsive element binding protein 1 (CREB1) and nuclear receptor subfamily 4 group A (NR4A) family-binding sites and a TSS; demethylation was accompanied by recruitment of CREB1 and NR4A1 and increased chromatin accessibility of the CYP11B2 promoter.	Potassium	0-9	cAMP responsive element binding protein 1	Homo sapiens	54-101
33657579-8	2021	Potassium stimulation caused DNA demethylation around cyclic AMP responsive element binding protein 1 (CREB1) and nuclear receptor subfamily 4 group A (NR4A) family-binding sites and a TSS; demethylation was accompanied by recruitment of CREB1 and NR4A1 and increased chromatin accessibility of the CYP11B2 promoter.	Potassium	0-9	cAMP responsive element binding protein 1	Homo sapiens	103-108
33657579-8	2021	Potassium stimulation caused DNA demethylation around cyclic AMP responsive element binding protein 1 (CREB1) and nuclear receptor subfamily 4 group A (NR4A) family-binding sites and a TSS; demethylation was accompanied by recruitment of CREB1 and NR4A1 and increased chromatin accessibility of the CYP11B2 promoter.	Potassium	0-9	cAMP responsive element binding protein 1	Homo sapiens	238-243
33657579-8	2021	Potassium stimulation caused DNA demethylation around cyclic AMP responsive element binding protein 1 (CREB1) and nuclear receptor subfamily 4 group A (NR4A) family-binding sites and a TSS; demethylation was accompanied by recruitment of CREB1 and NR4A1 and increased chromatin accessibility of the CYP11B2 promoter.	Potassium	0-9	nuclear receptor subfamily 4 group A member 1	Homo sapiens	248-253
33657579-8	2021	Potassium stimulation caused DNA demethylation around cyclic AMP responsive element binding protein 1 (CREB1) and nuclear receptor subfamily 4 group A (NR4A) family-binding sites and a TSS; demethylation was accompanied by recruitment of CREB1 and NR4A1 and increased chromatin accessibility of the CYP11B2 promoter.	Potassium	0-9	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	299-306
33657579-10	2021	DNA demethylation at CpG1 (Ad1), CpG2 (Ad5) and CpG3 were detected within 2 to 4 days after potassium (16 mmol/l) stimulation.	Potassium	92-101	amyloid beta precursor protein	Homo sapiens	27-30
33657579-10	2021	DNA demethylation at CpG1 (Ad1), CpG2 (Ad5) and CpG3 were detected within 2 to 4 days after potassium (16 mmol/l) stimulation.	Potassium	92-101	Alzheimer disease, familial, type 5	Homo sapiens	39-42
33657579-15	2021	CONCLUSION: : Potassium induced reversibly DNA demethylation, which switches the phenotype of CYP11B2 expression from an inactive to an active state.	Potassium	14-23	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	94-101
33925539-3	2021	The aldosterone synthase gene CYP11B2 is regulated by angiotensin II and potassium.	Potassium	73-82	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	4-24
33904208-2	2021	For an efficient synthesis, potassium hexafluorophosphate (KPF6 ) is employed as a cation template; PEG6DA as well as PEG6DMA recognizes the potassium cation with the hexa(ethylene glycol) spacer to dynamically form a pseudo-cyclic divinyl monomer.	Potassium	28-37	hexosaminidase subunit alpha	Homo sapiens	38-42
33904208-3	2021	Those monomers interacting with the potassium cations are efficiently polymerized with RAFT agents and radical initiators into cyclopolymers comprising 24-membered hexa(ethylene glycol) rings.	Potassium	36-45	hexosaminidase subunit alpha	Homo sapiens	164-168
33899306-0	2021	Effects of SGLT2 inhibition with Empagliflozin on Potassium Handling in Patients with Acute Heart Failure.	Potassium	50-59	solute carrier family 5 member 2	Homo sapiens	11-16
33899737-4	2021	We demonstrated that the essential factor controlling the diversity of the discharge pattern of embryonic V1R is the ratio of a persistent sodium conductance to a delayed rectifier potassium conductance.	Potassium	181-190	vomeronasal 1 receptor 51	Mus musculus	106-109
33925539-3	2021	The aldosterone synthase gene CYP11B2 is regulated by angiotensin II and potassium.	Potassium	73-82	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	30-37
33718825-5	2021	Using genetic and pharmacological inhibition, we show that the induction of mature IL-1beta is through a non-classical pathway dependent upon caspase-1, caspase-8, the NLRP3 inflammasome, potassium efflux, and autophagy while being independent of TRIF (TICAM1), vitamin D3, and pyroptosis.	Potassium	188-197	interleukin 1 alpha	Homo sapiens	83-91
33848364-4	2021	Until recently, the pathophysiology of hereditary xerocytosis was mainly believed to be based on the "PIEZO1-Gardos channel axis" in erythrocytes, according to which PIEZO1-activating mutations induce a calcium influx that secondarily activates the Gardos channel, leading to potassium and water efflux and subsequently to red blood cell dehydration.	Potassium	276-285	piezo type mechanosensitive ion channel component 1	Homo sapiens	102-108
33861365-5	2021	For patients with hyperkalemia during surgery, the odds ratios [ORs] of failure to decrease potassium (K+) after insulin treatment were higher in patients with eGFR < 30 mL/min/1.73 m2 (adjusted OR 3.24; 95% confidence interval 1.38-7.64; P = 0.007) than in patients with eGFR >= 60 mL/min/1.73 m2.	Potassium	92-101	insulin	Homo sapiens	113-120
33849496-8	2021	Restricted cubic spline analysis showed that potassium level was linearly and positively associated with long-term cancer mortality; HR per mmol/L 1.8, 95% CI 1.4-2.4.	Potassium	45-54	immunoglobulin kappa variable 1-13	Homo sapiens	145-150
33830722-0	2021	SnS2 Nanosheets Anchored on Nitrogen and Sulfur Co-Doped MXene Sheets for High-Performance Potassium-Ion Batteries.	Potassium	91-100	sodium voltage-gated channel alpha subunit 11	Homo sapiens	0-4
33848364-4	2021	Until recently, the pathophysiology of hereditary xerocytosis was mainly believed to be based on the "PIEZO1-Gardos channel axis" in erythrocytes, according to which PIEZO1-activating mutations induce a calcium influx that secondarily activates the Gardos channel, leading to potassium and water efflux and subsequently to red blood cell dehydration.	Potassium	276-285	piezo type mechanosensitive ion channel component 1	Homo sapiens	166-172
33741353-0	2021	A standardized glucose-insulin-potassium infusion protocol in surgical patients: use of real clinical data from a clinical data warehouse.	Potassium	31-40	insulin	Homo sapiens	23-30
33953928-1	2021	The sodium potassium ion channel (NaK) is a nonselective ion channel that conducts both sodium and potassium across the cellular membrane.	Potassium	11-20	TANK binding kinase 1	Homo sapiens	34-37
33829343-1	2021	The human ether-a-go-go related gene (hERG, KCNH2) encodes the pore-forming subunit of the potassium channel responsible for a fast component of the cardiac delayed rectifier potassium current (IKr).	Potassium	91-100	ETS transcription factor ERG	Homo sapiens	38-42
33829343-1	2021	The human ether-a-go-go related gene (hERG, KCNH2) encodes the pore-forming subunit of the potassium channel responsible for a fast component of the cardiac delayed rectifier potassium current (IKr).	Potassium	91-100	potassium voltage-gated channel subfamily H member 2	Homo sapiens	44-49
33826405-1	2021	Inward rectifying potassium (Kir) channels play important roles in both excitable and non-excitable cells of various organ systems and could represent valuable new drug targets for cardiovascular, metabolic, immune and neurological diseases.	Potassium	18-27	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	29-32
33688925-1	2021	The sodium/potassium-ATPase (NKA) is the enzyme that establishes gradients of sodium and potassium across the plasma membrane.	Potassium	11-20	tachykinin precursor 1	Homo sapiens	29-32
33688925-1	2021	The sodium/potassium-ATPase (NKA) is the enzyme that establishes gradients of sodium and potassium across the plasma membrane.	Potassium	89-98	tachykinin precursor 1	Homo sapiens	29-32
33741353-1	2021	AIMS: We evaluated the clinical usefulness of a new unified glucose-insulin-potassium (GIK) regimen in a general surgical department.	Potassium	76-85	insulin	Homo sapiens	68-75
33334222-5	2021	Results: Mutations in the KMT2D gene were identified in all of the 10 patients with KS.	Potassium	84-86	lysine methyltransferase 2D	Homo sapiens	26-31
33460257-0	2021	Potassium supplementation blunts the effects of high salt intake on serum retinol-binding protein 4 levels in healthy individuals.	Potassium	0-9	retinol binding protein 4	Homo sapiens	74-99
33460257-1	2021	AIMS/INTRODUCTION: Excessive dietary salt or low potassium intakes are strongly correlated with insulin resistance (IR) and type 2 diabetes mellitus.	Potassium	49-58	insulin	Homo sapiens	96-103
33460257-4	2021	This study aimed to assess whether salt consumption and potassium supplementation influence serum RBP4 levels in healthy individuals.	Potassium	56-65	retinol binding protein 4	Homo sapiens	98-102
33460257-10	2021	In addition, RBP4 levels presented positive (r = 0.528, P < 0.01) and negative (r = -0.506, P < 0.01) associations with 24-h urinary sodium- and potassium excretion levels.	Potassium	145-154	retinol binding protein 4	Homo sapiens	13-17
33460257-11	2021	CONCLUSIONS: RBP4 synthesis is motivated by high salt intake and revoked by potassium supplementation.	Potassium	76-85	retinol binding protein 4	Homo sapiens	13-17
33214722-6	2021	Proper management of serum potassium is required to ensure safe clinical use of MR blockers, including awareness of at-risk patient groups, choosing appropriate dosages for therapy initiation and dosage titration, and monitoring of serum potassium during therapy.	Potassium	27-36	nuclear receptor subfamily 3 group C member 2	Homo sapiens	80-82
33750980-12	2021	The SD1 were negatively correlated to soil pH, hydrogen (H+), potassium (K+) and carbon (C).	Potassium	62-71	CUP2Q35	Homo sapiens	4-7
33831355-5	2021	This structure, representing a key nucleotide-free activation intermediate, reveals how the potassium ion-binding K loop disrupts the nucleotide-binding site of Sar1.	Potassium	92-101	Arf family GTPase SAR1	Saccharomyces cerevisiae S288C	161-165
33752589-4	2021	Ka and Ks analyses revealed that in G. hirsutum ARF genes have undergone asymmetric evolution in the two subgenomes.	Potassium	7-9	ADP-ribosylation factor 2-B	Gossypium hirsutum	48-51
33607471-1	2021	Bartter Syndrome (BS) is a group of rare inherited autosome-recessive disease, which can be caused by the gene mutations of sodium-potassium-chloride cotransporter gene (SLC12A1).	Potassium	131-140	solute carrier family 12 member 1	Homo sapiens	170-177
33783609-2	2021	Therefore, this study aimed to investigate the role of potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1), a member of the lncRNA voltage-gated channel subfamily Q, in the development of osteoarthritis.	Potassium	55-64	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	134-142
33870140-0	2021	Potassium ions promote hexokinase-II dependent glycolysis.	Potassium	0-9	hexokinase 2	Homo sapiens	23-36
33450182-4	2021	However, the drug inhibition mechanism remains unclear because of the scarce structural information regarding the drug- and potassium-bound hERG channels.	Potassium	124-133	ETS transcription factor ERG	Homo sapiens	140-144
34001444-4	2021	RESULTS: Endometriosis was associated with increased thrombin generation, reflected by both higher F1+2 (+96.1%, P = 0.005) and ETP (+14.2%, P = 0.014) along with unfavourably altered fibrin clot properties represented by lower Ks (-31%, P < 0.001) and prolonged CLT (+13.5%, P = 0.02), compared with the non-endometriosis group.	Potassium	228-230	coagulation factor II, thrombin	Homo sapiens	53-61
33508244-3	2021	Here we report a surprising but crucial function independent of potassium conductance: by organizing the F-actin cytoskeleton in mouse nerve terminals, the Kv3.3 protein facilitates slow endocytosis, rapid endocytosis, vesicle mobilization to the readily releasable pool, and recovery of synaptic depression during repetitive firing.	Potassium	64-73	potassium voltage gated channel, Shaw-related subfamily, member 3	Mus musculus	156-161
33239270-2	2021	The K+-Cl- cotransporter KCC2 is responsible for Cl- extrusion and restoration of [Cl-]i equilibrium (ECl) after synaptic activity, but at the cost of increased extracellular potassium which may retard K+-Cl- extrusion, depolarize neurons, and potentiate seizures.	Potassium	175-184	solute carrier family 12 member 5	Homo sapiens	25-29
33450182-5	2021	In this study, we obtained the cryo-EM density map of potassium-bound hERG channel complexed with astemizole, a well-known hERG inhibitor that increases risk of potentially fatal arrhythmia, at 3.5-A resolution.	Potassium	54-63	ETS transcription factor ERG	Homo sapiens	70-74
33450182-5	2021	In this study, we obtained the cryo-EM density map of potassium-bound hERG channel complexed with astemizole, a well-known hERG inhibitor that increases risk of potentially fatal arrhythmia, at 3.5-A resolution.	Potassium	54-63	ETS transcription factor ERG	Homo sapiens	123-127
33040444-0	2021	Letrozole targets the Human ether-a-go-go-related gene (HERG) potassium current in glioblastoma.	Potassium	62-71	potassium voltage-gated channel subfamily H member 2	Homo sapiens	56-60
33394730-7	2021	This chloride-sensing mechanism requires basolateral potassium and chloride channels or cotransporters, including Kir4.1/5.1, ClC-Kb, and possibly KCCs, to modulate [Cl-]i in response to the changes of plasma potassium.	Potassium	53-62	chloride channel, voltage-sensitive Kb	Mus musculus	126-132
33394730-7	2021	This chloride-sensing mechanism requires basolateral potassium and chloride channels or cotransporters, including Kir4.1/5.1, ClC-Kb, and possibly KCCs, to modulate [Cl-]i in response to the changes of plasma potassium.	Potassium	53-62	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	114-124
33394730-9	2021	The understanding of chloride-mediated regulation of WNK4 explains the inverse relationship between dietary potassium intake and NCC activity.	Potassium	108-117	WNK lysine deficient protein kinase 4	Mus musculus	53-57
33393091-4	2021	Here, we examined the effect of TRPV4 activation on the delayed rectifier potassium current (IK) in hippocampal pyramidal neurons and on the Kv subunits expression in male mice.	Potassium	74-83	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	32-37
33542107-0	2021	Heterozygosity for a Pathogenic Variant in SLC12A3 That Causes Autosomal Recessive Gitelman Syndrome Is Associated with Lower Serum Potassium.	Potassium	132-141	solute carrier family 12 member 3	Homo sapiens	43-50
33542107-11	2021	CONCLUSIONS: This study provides evidence that heterozygosity for a pathogenic variant in SLC12A3 causing Gitelman syndrome, a canonically recessive disorder, contributes to serum potassium concentration.	Potassium	180-189	solute carrier family 12 member 3	Homo sapiens	90-97
33111209-1	2021	BACKGROUND: Hydrogen/potassium ATPase beta (ATP4B) is a proton pump acting an essential role in gastric acid secretion.	Potassium	21-30	ATPase H+/K+ transporting subunit beta	Homo sapiens	44-49
33229908-3	2021	Various approaches are used to overcome this drawback, including the injection of a "synthetic" inward rectifier potassium current (IK1), which is computed in real time, based on the recorded membrane potential ("dynamic clamp").	Potassium	113-122	IKAROS family zinc finger 1	Homo sapiens	132-135
33606926-16	2021	Patients with reported high critical serum potassium values were characterized by high rates of comorbidity, reduced eGFR, and mortality.	Potassium	43-52	epidermal growth factor receptor	Homo sapiens	117-121
33346797-3	2021	Upregulated LRRC55 and increased intracellular Ca2+ led to BK channel activation and the loss of intracellular potassium, resulting in apoptosome formation and caspase-3 activation in angiotensin II (Ang II)-treated podocytes.	Potassium	111-120	leucine rich repeat containing 55	Homo sapiens	12-18
33346797-3	2021	Upregulated LRRC55 and increased intracellular Ca2+ led to BK channel activation and the loss of intracellular potassium, resulting in apoptosome formation and caspase-3 activation in angiotensin II (Ang II)-treated podocytes.	Potassium	111-120	angiotensinogen	Homo sapiens	184-198
33708784-7	2021	Moreover, two new potassium-lowering therapies have shown to improve tolerance, allowing for higher dosage of renin-angiotensin system inhibitors and therefore enhancing their nephroprotective effect.	Potassium	18-27	renin	Homo sapiens	110-115
33604622-2	2021	In this study, we investigate the effects of ammonium and potassium on the activity of maize GDH.	Potassium	58-67	glutamic dehydrogenase1	Zea mays	93-96
33679687-9	2020	In vivo, administration of glucose-insulin-potassium reduced serum IL-1beta level, intestinal ASC speck formation, local macrophage infiltration and alleviated intestinal injury in mice exposed to LPS.	Potassium	43-52	interleukin 1 alpha	Mus musculus	67-75
33679687-9	2020	In vivo, administration of glucose-insulin-potassium reduced serum IL-1beta level, intestinal ASC speck formation, local macrophage infiltration and alleviated intestinal injury in mice exposed to LPS.	Potassium	43-52	PYD and CARD domain containing	Homo sapiens	94-97
33599929-4	2021	The variance analysis method was used to analyze the difference in the soil pH values, soil organic matter (SOM) content, soil total nitrogen (STN) content, soil available phosphorus (SAP) content and soil available potassium (SAK) content of the reconstructed soil, and the reasons for the difference were discussed.	Potassium	216-225	Sak kinase	Drosophila melanogaster	227-230
33604622-3	2021	Our results show that both ammonium and potassium play multiple roles in regulating the activity of maize GDH, with the specific roles depending on the concentration of potassium.	Potassium	40-49	glutamic dehydrogenase1	Zea mays	106-109
33604622-3	2021	Our results show that both ammonium and potassium play multiple roles in regulating the activity of maize GDH, with the specific roles depending on the concentration of potassium.	Potassium	169-178	glutamic dehydrogenase1	Zea mays	106-109
33604622-4	2021	Together with the structural information of GDH, we propose models for the substrate inhibition of ammonium, and the elimination of substrate inhibition by potassium.	Potassium	156-165	glutamic dehydrogenase1	Zea mays	44-47
33604622-6	2021	We also analyze the binding sites of ammonium and potassium on maize GDH, and the conformational changes of maize GDH.	Potassium	50-59	glutamic dehydrogenase1	Zea mays	69-72
33604622-7	2021	The findings provide insight into the regulation of maize GDH activity by ammonium and potassium and reveal the importance of the dose and ratio of nitrogen and potassium in crop cultivation.	Potassium	87-96	glutamic dehydrogenase1	Zea mays	58-61
33604622-7	2021	The findings provide insight into the regulation of maize GDH activity by ammonium and potassium and reveal the importance of the dose and ratio of nitrogen and potassium in crop cultivation.	Potassium	161-170	glutamic dehydrogenase1	Zea mays	58-61
33080499-5	2021	This demonstrates that the Ge@C-CMK electrode possesses promising application potential as an alternative anode in sodium and potassium ion storage applications.	Potassium	126-135	C-X-C motif chemokine ligand 9	Homo sapiens	32-35
33763649-4	2021	A fundamental mechanism underlying functional hyperemia is activation of capillary endothelial inward-rectifying K+ (Kir2.1) channels by neuronally derived potassium (K+), which evokes a retrograde capillary-to-arteriole electrical signal that dilates upstream arterioles, increasing blood delivery to downstream active regions.	Potassium	156-165	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	117-123
33268067-0	2021	Boosting potassium-ion storage in large-diameter carbon nanotubes/MoP hybrid.	Potassium	9-18	opioid receptor mu 1	Homo sapiens	66-69
32987266-3	2021	In this work, we have focused on the design and synthesis of a pentacyano organic anion and potassium cation based 3D coordination polymer (5CNP).	Potassium	92-101	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	141-144
33633824-1	2021	Background: The urinary sodium potassium (NaK) ratio is associated with dietary sodium and potassium intake and blood pressure, and it also reflects the activity of aldosterone.	Potassium	31-40	TANK binding kinase 1	Homo sapiens	42-45
33633824-8	2021	Conclusions: uPA patients with a lower urinary NaK ratio, due to high plasma aldosterone and low serum potassium concentrations, were more likely to have clinical success after adrenalectomy.	Potassium	103-112	TANK binding kinase 1	Homo sapiens	47-50
33570024-2	2021	Glycyrrhizin in licorice root activates the renal mineralocorticoid receptor increasing sodium reabsorption and potassium excretion.	Potassium	112-121	nuclear receptor subfamily 3 group C member 2	Homo sapiens	50-76
33390050-4	2021	Conversely, oral potassium induces NCC downregulation producing potassium-induced natriuresis.	Potassium	64-73	solute carrier family 12 member 3	Homo sapiens	35-38
33542419-1	2021	Soil available phosphorus (SAP) and soil available potassium (SAK) are important elements in the growth of plants.	Potassium	51-60	polo like kinase 4	Homo sapiens	62-65
33854899-0	2021	Ultrafine MoP Nanoparticle Splotched Nitrogen-Doped Carbon Nanosheets Enabling High-Performance 3D-Printed Potassium-Ion Hybrid Capacitors.	Potassium	107-116	opioid receptor mu 1	Homo sapiens	10-13
33854899-5	2021	It is further confirmed via density functional theory calculations that the smaller the MoP nanoparticle, the larger the three-phase boundary achieved for favoring competitive binding energy toward potassium ions.	Potassium	198-207	opioid receptor mu 1	Homo sapiens	88-91
33144140-5	2021	RT-PCR and Western blot were employed to study the effects of potassium and resveratrol on the SGK1 isoform expression.	Potassium	62-71	serum/glucocorticoid regulated kinase 1	Homo sapiens	95-99
33144140-6	2021	RESULTS: The SGK1 gene encodes a G4 structure in the proximal upstream of promoter-2; the G4 structure is stabilized by potassium or resveratrol, but destabilized by sodium.	Potassium	120-129	serum/glucocorticoid regulated kinase 1	Homo sapiens	13-17
33144140-7	2021	Super-physiological levels of sodium stimulate the transcription of all SGK1 isoforms, whereas resveratrol or potassium supplementation inhibits the transcription of iso-2 and iso-3, but not iso-1.	Potassium	110-119	eukaryotic translation initiation factor 1	Homo sapiens	191-196
33144140-8	2021	CONCLUSIONS: Stabilizing the G4 by potassium or resveratrol induces alternative promoter usage and/or pre-mRNA splicing in the transcription of SGK1.	Potassium	35-44	serum/glucocorticoid regulated kinase 1	Homo sapiens	144-148
33416459-0	2021	Caveolin-3 is required for regulation of transient outward potassium current by angiotensin II in mouse atrial myocytes.	Potassium	59-68	caveolin 3	Mus musculus	0-10
33416459-0	2021	Caveolin-3 is required for regulation of transient outward potassium current by angiotensin II in mouse atrial myocytes.	Potassium	59-68	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	80-94
33416459-1	2021	Angiotensin II (AngII) is a key mediator of the renin-angiotensin system and plays an important role in the regulation of cardiac electrophysiology by affecting various cardiac ion currents, including transient outward potassium current Ito.	Potassium	219-228	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-14
33416459-1	2021	Angiotensin II (AngII) is a key mediator of the renin-angiotensin system and plays an important role in the regulation of cardiac electrophysiology by affecting various cardiac ion currents, including transient outward potassium current Ito.	Potassium	219-228	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	16-21
33144140-9	2021	GENERAL SIGNIFICANCE: Potassium/sodium ion balance or resveratrol binding can act to regulate G4 molecular switches for controlling SGK1 gene expression, thereby presenting a new avenue for drug development.	Potassium	22-31	serum/glucocorticoid regulated kinase 1	Homo sapiens	132-136
33390050-0	2021	Thiazide-Sensitive NCC (Sodium-Chloride Cotransporter) in Human Metabolic Syndrome: Sodium Sensitivity and Potassium-Induced Natriuresis.	Potassium	107-116	solute carrier family 12 member 3	Homo sapiens	19-22
33390050-4	2021	Conversely, oral potassium induces NCC downregulation producing potassium-induced natriuresis.	Potassium	17-26	solute carrier family 12 member 3	Homo sapiens	35-38
33507417-13	2021	There were positive correlations between SIRT1 levels and each of the hemoglobin levels and serum potassium levels.	Potassium	98-107	sirtuin 1	Homo sapiens	41-46
33572566-10	2021	Knowledge gained from structural and functional studies using activators or inhibitors of the potassium current mediated by KV4/KChIPs will better help understand the underlying mechanism involving KV4-mediated-channelopathies, establishing the foundations for drug discovery, and hence their treatments.	Potassium	94-103	potassium voltage-gated channel subfamily C member 1	Homo sapiens	124-127
33572566-10	2021	Knowledge gained from structural and functional studies using activators or inhibitors of the potassium current mediated by KV4/KChIPs will better help understand the underlying mechanism involving KV4-mediated-channelopathies, establishing the foundations for drug discovery, and hence their treatments.	Potassium	94-103	potassium voltage-gated channel subfamily C member 1	Homo sapiens	198-201
33047410-5	2021	Plants acquire more NO3 - than NH4 + when accumulating high potassium (K), calcium (Ca), and magnesium (Mg) to maintain charge balance.	Potassium	60-69	NBL1, DAN family BMP antagonist	Homo sapiens	20-23
33509163-7	2021	We also demonstrate that this decrease in potassium current lowers the threshold for denatonium to stimulate human beta-defensin-2 release.	Potassium	42-51	defensin beta 4B	Homo sapiens	115-130
33499915-0	2021	A nutrient pattern characterized by vitamin A, C, B6, potassium, and fructose is associated with reduced risk of insulin-related disorders: A prospective study among participants of Tehran lipid and glucose study.	Potassium	54-63	insulin	Homo sapiens	113-120
33499915-13	2021	CONCLUSIONS: Present study showed that high adherence to a nutrient pattern rich in vitamin A, vitamin C, pyridoxine, potassium, and fructose is inversely associated with 3-years changes in insulin, HOMA-IR, and directly associated with HOMA-S.	Potassium	118-127	insulin	Homo sapiens	190-197
33614016-7	2021	The main ions involved in PH are calcium ion (Ca2+), potassium ion (K+), sodium ion (Na+) and chloride ion (Cl-).	Potassium	53-62	phenylalanine hydroxylase	Homo sapiens	26-28
33546058-7	2021	OUTCOMES: Her blood pressure, serum potassium, and plasma renin levels were reversed after treatment with angiotensin-converting enzyme inhibitors.	Potassium	36-45	angiotensin I converting enzyme	Homo sapiens	106-135
33373586-2	2021	The pore-forming alpha-subunit KCNQ1, which belongs to the voltage-gated ion channel superfamily, associates to its beta-auxiliary subunit KCNE1 to generate the slow cardiac potassium IKs current, whose dysfunction leads to cardiac arrhythmia.	Potassium	174-183	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	31-36
33373586-2	2021	The pore-forming alpha-subunit KCNQ1, which belongs to the voltage-gated ion channel superfamily, associates to its beta-auxiliary subunit KCNE1 to generate the slow cardiac potassium IKs current, whose dysfunction leads to cardiac arrhythmia.	Potassium	174-183	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	139-144
33628092-12	2021	The activation of nuclear factor-kappaB (NF-kappaB) increased the expression of pro-inflammatory cytokines, and sodium-potassium-chloride co-transporter isoform 1 (NKCC1).	Potassium	119-128	nuclear factor kappa B subunit 1	Homo sapiens	18-39
33498651-1	2021	KCNQ1 encodes the voltage-gated potassium (Kv) channel KCNQ1, also known as KvLQT1 or Kv7.1.	Potassium	32-41	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-5
33498651-1	2021	KCNQ1 encodes the voltage-gated potassium (Kv) channel KCNQ1, also known as KvLQT1 or Kv7.1.	Potassium	32-41	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	55-60
33498651-1	2021	KCNQ1 encodes the voltage-gated potassium (Kv) channel KCNQ1, also known as KvLQT1 or Kv7.1.	Potassium	32-41	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	76-82
33498651-1	2021	KCNQ1 encodes the voltage-gated potassium (Kv) channel KCNQ1, also known as KvLQT1 or Kv7.1.	Potassium	32-41	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	86-91
33628092-12	2021	The activation of nuclear factor-kappaB (NF-kappaB) increased the expression of pro-inflammatory cytokines, and sodium-potassium-chloride co-transporter isoform 1 (NKCC1).	Potassium	119-128	nuclear factor kappa B subunit 1	Homo sapiens	41-50
33628092-12	2021	The activation of nuclear factor-kappaB (NF-kappaB) increased the expression of pro-inflammatory cytokines, and sodium-potassium-chloride co-transporter isoform 1 (NKCC1).	Potassium	119-128	solute carrier family 12 member 2	Homo sapiens	164-169
33431687-10	2021	These results demonstrate that normal potassium flux through LRRC26-associated BK channels in GCs has protective effects against colitis in mice.	Potassium	38-47	leucine rich repeat containing 26	Mus musculus	61-67
33435938-11	2021	With RNAseq transcriptomic analysis of the expression profiling from the muscle specimens, it surprisingly discloses large downregulation of genes involved in pathways of sodium, potassium, and calcium channels, which can be rescued by L-carnitine treatment, fatty acid metabolism was differentially dysregulated in TPM3(E151G) fish and rescued by L-carnitine treatment.	Potassium	179-188	tropomyosin 3	Homo sapiens	316-320
33498219-0	2021	MST3 Involvement in Na+ and K+ Homeostasis with Increasing Dietary Potassium Intake.	Potassium	67-76	serine/threonine kinase 24	Mus musculus	0-4
33467005-5	2021	Spectral, functional and structural characterization of the inhibitory complexes showed that a one-atom head-group linker elongation, from pyridyl-ethyl to pyridyl-propyl, was beneficial and markedly improved Ks, IC50 and thermostability of CYP3A4.	Potassium	209-211	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	241-247
33436713-8	2021	The main independent risk factors associated with 72-h mortality among patients with AST levels >= 3000 U/L included higher serum values of alkaline phosphatase, creatine kinase, serum sodium, potassium, and phosphorus.	Potassium	193-202	solute carrier family 17 member 5	Homo sapiens	85-88
33585337-7	2021	We also discuss the clinical approach and the specificities of managing this rare hereditary renal tubulopathy.. LEARNING POINTS: Gitelman syndrome is a rare cause of persistent hypokalaemia.A definitive diagnosis is determined by the identification of mutations in the SLC12A3 gene.Management consists of chronic potassium and magnesium supplementation aimed at symptom control.	Potassium	314-323	solute carrier family 12 member 3	Homo sapiens	270-277
32634539-9	2021	In striatum, basal extracellular levels and potassium-evoked DA release were significantly reduced in mice lacking Casp3, a clear indication of dopaminergic hypofunction in dopaminergic innervating tissues.	Potassium	44-53	caspase 3	Mus musculus	115-120
33889232-12	2021	In contrast, the correlation between serum potassium and serum albumin and that between serum potassium and serum calcium was not significant.	Potassium	43-52	albumin	Homo sapiens	63-70
33440655-6	2021	Electrophysiological experiments further revealed that AEG-1 further regulates TWIK-1-mediated potassium currents in normal astrocytes.	Potassium	95-104	metadherin	Homo sapiens	55-60
33440655-6	2021	Electrophysiological experiments further revealed that AEG-1 further regulates TWIK-1-mediated potassium currents in normal astrocytes.	Potassium	95-104	potassium two pore domain channel subfamily K member 1	Homo sapiens	79-85
33490276-16	2021	LpqH protein has good immunogenicity and can activate the NLRP3 inflammasome through the potassium efflux pathway without causing cell death.	Potassium	89-98	NLR family, pyrin domain containing 3	Mus musculus	58-63
33402705-0	2021	FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currents.	Potassium	126-135	forkhead box P1	Mus musculus	0-5
33718604-10	2021	The patient"s ACTH hypersecretion and hypokalemia were treated with potassium replacement, amiloride, and ketoconazole.	Potassium	68-77	proopiomelanocortin	Homo sapiens	14-18
33412877-2	2021	Like in the well-established direct random phase approximation (dRPA), sigma-functionals require as input exclusively eigenvalues sigma of the frequency-dependent KS response function.	Potassium	163-165	Replication Protein A 70	Drosophila melanogaster	64-68
33112610-1	2021	Variants of the SLC24A5 gene, which encodes a putative potassium-dependent sodium-calcium exchanger (NCKX5) that most likely resides in the melanosome or its precursor, affect pigmentation in both humans and zebrafish (Danio rerio).	Potassium	55-64	solute carrier family 24 member 5	Homo sapiens	16-23
33112610-1	2021	Variants of the SLC24A5 gene, which encodes a putative potassium-dependent sodium-calcium exchanger (NCKX5) that most likely resides in the melanosome or its precursor, affect pigmentation in both humans and zebrafish (Danio rerio).	Potassium	55-64	solute carrier family 24 member 5	Homo sapiens	101-106
33220920-6	2021	We then identified 9 compounds that inhibited the CYP11B2 expression induced by potassium-mediated depolarization from the validated compound library (3399 compounds).	Potassium	80-89	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	50-57
32888379-4	2021	Computer calculations were performed using pharmacokinetic and pharmacodynamic data, including affinity to block the rapid component of the delayed rectifier cardiac potassium current (IKr ) encoded by the human ether-a-go-go gene (hERG), propensity to prolong cardiac repolarization (QT interval) and cause torsade de pointes (TdP).	Potassium	166-175	ETS transcription factor ERG	Homo sapiens	232-236
31904168-0	2021	The MORN domain of Junctophilin2 regulates functional interactions with small-conductance Ca2+ -activated potassium channel subtype2 (SK2).	Potassium	106-115	junctophilin 2	Homo sapiens	19-32
31904168-0	2021	The MORN domain of Junctophilin2 regulates functional interactions with small-conductance Ca2+ -activated potassium channel subtype2 (SK2).	Potassium	106-115	potassium calcium-activated channel subfamily N member 2	Homo sapiens	134-137
33288445-0	2021	Corrigendum to "Exaggerated potassium current reduction by oxytocin in visceral sensory neurons following chronic intermittent hypoxia" [Auton Neurosci.	Potassium	28-37	oxytocin/neurophysin I prepropeptide	Homo sapiens	59-67
33518654-14	2021	Similarly, Potassium Inwardly Rectifying Channel Subfamily J Member 6 (KCNJ6) was enriched in the function of an ion channel complex.	Potassium	11-20	potassium inwardly rectifying channel subfamily J member 6	Homo sapiens	71-76
33357781-5	2021	It is well known that extracellular glutamate levels and glutamate intrasynaptic time-coursing are maintained by perisynaptic astrocytes, where inwardly rectifying potassium channels 4.1 (Kir4.1 channels) regulate both potassium and glutamate uptake.	Potassium	164-173	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	188-194
33124684-4	2021	Neurons dissected from YFP-GIRK1 mice had significantly reduced potassium currents and this mouse line phenotypically resembled GIRK1 null mice, making it a "functional knockdown" model of GIRK1-containing channels.	Potassium	64-73	potassium inwardly-rectifying channel, subfamily J, member 3	Mus musculus	27-32
33357781-6	2021	In addition, ketamine reduces membrane expression of Kir4.1 channels, which raises extracellular potassium and glutamate levels, increasing postsynaptic neural activities.	Potassium	97-106	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	53-59
33424762-1	2020	Astrocytes regulate potassium and glutamate homeostasis via inwardly rectifying potassium (Kir) 4.1 channels in synapses, maintaining normal neural excitability.	Potassium	20-29	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	80-99
32553901-1	2021	TWIK-related K+ channel (TREK-1) two-pore-domain potassium (K2P) channels mediate background potassium currents and regulate cellular excitability in many different types of cells.	Potassium	49-58	potassium two pore domain channel subfamily K member 2	Homo sapiens	25-31
33367898-4	2021	In Arabidopsis, the CIPK23 kinase has emerged as a major hub driving root responses to diverse environmental stresses including drought, salinity and nutrient imbalances such as potassium, nitrate and iron deficiencies as well as ammonium, magnesium and non-iron metals toxicities.	Potassium	178-187	CBL-interacting protein kinase 23	Arabidopsis thaliana	20-26
33132203-3	2021	The voltage-gated potassium channel KV2.1, encoded by KCNB1, is primarily responsible for delayed rectifier potassium currents that are important regulators of excitability in electrically excitable cells, including neurons.	Potassium	18-27	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	36-41
33132203-3	2021	The voltage-gated potassium channel KV2.1, encoded by KCNB1, is primarily responsible for delayed rectifier potassium currents that are important regulators of excitability in electrically excitable cells, including neurons.	Potassium	18-27	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	54-59
33132203-4	2021	In addition to its canonical role as a voltage-gated potassium conductance, KV2.1 also serves a highly conserved structural function organizing endoplasmic reticulum-plasma membrane junctions clustered in the soma and proximal dendrites of neurons.	Potassium	53-62	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	76-81
32998136-11	2021	For example, the serum potassium level in the FMO3 E308G genotype group was significantly lower than that in the WT group (p = 0.028), the abnormal level of total bilirubin in the FMO3 E308G genotype group was significantly higher than that in the WT group (p = 0.049), and the aspartate aminotransferase level in the E308G group was significantly higher than that in the WT group (p = 0.05).	Potassium	23-32	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	46-50
33424762-3	2020	Specifically, Kir4.1 channel inhibition by KCNJ10 gene mutation or expressional down-regulation increases the extracellular levels of potassium ions and glutamate in synapses and causes hyperexcitation of neurons.	Potassium	134-143	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	14-20
33424762-3	2020	Specifically, Kir4.1 channel inhibition by KCNJ10 gene mutation or expressional down-regulation increases the extracellular levels of potassium ions and glutamate in synapses and causes hyperexcitation of neurons.	Potassium	134-143	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	43-49
33310850-1	2020	Potassium-chloride cotransporters KCC1 to KCC4 mediate the coupled export of potassium and chloride across the plasma membrane and play important roles in cell volume regulation, auditory system function, and gamma-aminobutyric acid (GABA) and glycine-mediated inhibitory neurotransmission.	Potassium	77-86	solute carrier family 12 member 4	Homo sapiens	34-38
33419247-3	2020	There is substantial evidence that c-peptide counteracts the detrimental changes caused by hyperglycemia at the cellular level, such as decreased activation of endothelial nitric oxide synthase and sodium potassium ATPase, and increase in formation of pro-inflammatory molecules mediated by nuclear factor kappa-light-chain-enhancer of activated B cells: cytokines, chemokines, cell adhesion molecules, vascular endothelial growth factor, and transforming growth factor beta.	Potassium	205-214	insulin	Homo sapiens	35-44
33437379-4	2020	Potassium currents were recorded by whole-cell patch clamping in HEK293 cells transiently transfected with wild-type and/or mutant hERG potassium channel.	Potassium	0-9	ETS transcription factor ERG	Homo sapiens	131-135
33310850-1	2020	Potassium-chloride cotransporters KCC1 to KCC4 mediate the coupled export of potassium and chloride across the plasma membrane and play important roles in cell volume regulation, auditory system function, and gamma-aminobutyric acid (GABA) and glycine-mediated inhibitory neurotransmission.	Potassium	77-86	solute carrier family 12 member 7	Homo sapiens	42-46
33321932-3	2020	Patch-clamp recordings of goblet cells located in freshly excised rat conjunctiva reveal that these mucin-releasing cells respond to sustained hyperosmolarity by sequentially activating their ATP-sensitive potassium (KATP), nonspecific cation (NSC), voltage-gated calcium (VGCC), and P2X7 channels; each of which modulates exocytosis.	Potassium	206-215	solute carrier family 13 member 2	Rattus norvegicus	100-105
33343935-9	2020	The negative association between SP-A1 and Ks was found in mild, moderate, and severe keratoconus eyes (r mild = -0.171, r moderate = -0.317, r severe = -0.288, all P < 0.05).	Potassium	43-45	surfactant protein A1	Homo sapiens	33-38
33363455-15	2020	The levels of inwardly rectifying potassium (Kir 4.1) channels were also downregulated in astrocytes in the WT post-PTZ, while its levels did not change in KO groups.	Potassium	34-43	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	45-52
33424864-0	2020	Distinct Molecular Mechanisms Underlying Potassium Efflux for NLRP3 Inflammasome Activation.	Potassium	41-50	NLR family pyrin domain containing 3	Homo sapiens	62-67
33424864-2	2020	Potassium efflux has been reported to be essential for NLRP3 inflammasome activation by structurally diverse pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs).	Potassium	0-9	NLR family pyrin domain containing 3	Homo sapiens	55-60
33424864-3	2020	Thus, the molecular mechanisms underlying potassium efflux to activate NLRP3 inflammasome are under extensive investigation.	Potassium	42-51	NLR family pyrin domain containing 3	Homo sapiens	71-76
33424864-4	2020	Here, we review current knowledge about the distinction channels or pore-forming proteins underlying potassium efflux for NLRP3 inflammasome activation with canonical/non-canonical signaling or following caspase-8 induced pyroptosis.	Potassium	101-110	NLR family pyrin domain containing 3	Homo sapiens	122-127
33424864-4	2020	Here, we review current knowledge about the distinction channels or pore-forming proteins underlying potassium efflux for NLRP3 inflammasome activation with canonical/non-canonical signaling or following caspase-8 induced pyroptosis.	Potassium	101-110	caspase 8	Homo sapiens	204-213
33362470-8	2020	Importantly, NGN2iSNs repetitively fire action potentials (APs) supported by voltage-gated sodium, potassium, and calcium conductances.	Potassium	99-108	neurogenin 2	Rattus norvegicus	13-17
32990398-9	2020	Functional verification showed that the KCNAB3 mutation could accelerate the inactivation of potassium channels, thus inhibiting potassium current, increasing neuronal excitability, and promoting epileptic convulsion.	Potassium	93-102	potassium voltage-gated channel subfamily A regulatory beta subunit 3	Homo sapiens	40-46
33035439-12	2020	Our results suggest that redox-activated PKA may be important for H2O2-dependent arrhythmias and could be important for the development of specific antiarrhythmic drugs.NEW & NOTEWORTHY Oxidation-activated PKA type I inhibits transient outward potassium current (Ito) and inward rectifying potassium current (IK1) and contributes to ROS-induced APD prolongation as well as generation of early afterdepolarizations in murine ventricular cardiomyocytes.	Potassium	244-253	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	309-312
33035439-12	2020	Our results suggest that redox-activated PKA may be important for H2O2-dependent arrhythmias and could be important for the development of specific antiarrhythmic drugs.NEW & NOTEWORTHY Oxidation-activated PKA type I inhibits transient outward potassium current (Ito) and inward rectifying potassium current (IK1) and contributes to ROS-induced APD prolongation as well as generation of early afterdepolarizations in murine ventricular cardiomyocytes.	Potassium	290-299	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	309-312
33323459-2	2020	Recent studies suggest NIMA-related kinase 7 (NEK7) is necessary for NLRP3 inflammasome activation during potassium efflux.	Potassium	106-115	NIMA related kinase 7	Homo sapiens	23-44
33323459-2	2020	Recent studies suggest NIMA-related kinase 7 (NEK7) is necessary for NLRP3 inflammasome activation during potassium efflux.	Potassium	106-115	NIMA related kinase 7	Homo sapiens	46-50
33323459-2	2020	Recent studies suggest NIMA-related kinase 7 (NEK7) is necessary for NLRP3 inflammasome activation during potassium efflux.	Potassium	106-115	NLR family pyrin domain containing 3	Homo sapiens	69-74
32253972-2	2020	A frequent cause for LQTS are mutations in the KCNH2 gene (also known as the human ether-a-go-go-related gene or hERG), which reduce or modulate the potassium current IKr and hence alter cardiac repolarization.	Potassium	149-158	potassium voltage-gated channel subfamily H member 2	Homo sapiens	47-52
32253972-2	2020	A frequent cause for LQTS are mutations in the KCNH2 gene (also known as the human ether-a-go-go-related gene or hERG), which reduce or modulate the potassium current IKr and hence alter cardiac repolarization.	Potassium	149-158	ETS transcription factor ERG	Homo sapiens	113-117
32617840-0	2020	GIRK1-Mediated Inwardly Rectifying Potassium Current Is a Candidate Mechanism Behind Purkinje Cell Excitability, Plasticity, and Neuromodulation.	Potassium	35-44	potassium inwardly-rectifying channel, subfamily J, member 3	Mus musculus	0-5
32790646-7	2020	Together, these new WNK1 genetic variants highlight the importance of the KS-WNK1 isoform abundance on potassium homeostasis.	Potassium	103-112	WNK lysine deficient protein kinase 1	Mus musculus	20-24
32307195-10	2020	A 20-mmol increase in potassium intake during follow-up was associated with a 24% reduction in renal outcome.	Potassium	22-31	immunoglobulin kappa variable 1-27	Homo sapiens	0-4
32307195-10	2020	A 20-mmol increase in potassium intake during follow-up was associated with a 24% reduction in renal outcome.	Potassium	22-31	immunoglobulin kappa variable 2-23 (pseudogene)	Homo sapiens	76-80
32075457-5	2020	We have found a unique Nrf2 inactivator, named K67, that inhibited the PPI between Keap1 and p-p62 and attenuated sorafenib resistance in Huh-1 cells.	Potassium	47-50	NFE2 like bZIP transcription factor 2	Homo sapiens	23-27
32075457-5	2020	We have found a unique Nrf2 inactivator, named K67, that inhibited the PPI between Keap1 and p-p62 and attenuated sorafenib resistance in Huh-1 cells.	Potassium	47-50	kelch like ECH associated protein 1	Homo sapiens	83-88
32075457-5	2020	We have found a unique Nrf2 inactivator, named K67, that inhibited the PPI between Keap1 and p-p62 and attenuated sorafenib resistance in Huh-1 cells.	Potassium	47-50	docking protein 1	Homo sapiens	93-98
32790646-7	2020	Together, these new WNK1 genetic variants highlight the importance of the KS-WNK1 isoform abundance on potassium homeostasis.	Potassium	103-112	WNK lysine deficient protein kinase 1	Mus musculus	77-81
33255956-5	2020	Monopotassium salts of homopolyether-diols, i.e., PPO-diol, PBO-diol, and PAGE-diol, appeared to be useful macroinitiators for the preparation of new triblock copolyether-diols by polymerization of glycidyl ethers.	Potassium	0-13	protoporphyrinogen oxidase	Homo sapiens	50-53
32621119-6	2020	MLKL-induced caspase-1 activation and IL-1beta maturation were abolished by NLR family, pyrin domain-containing 3 (NLRP3) specific inhibitor MCC950, or extracellular high potassium concentration.	Potassium	171-180	mixed lineage kinase domain like pseudokinase	Homo sapiens	0-4
32621119-6	2020	MLKL-induced caspase-1 activation and IL-1beta maturation were abolished by NLR family, pyrin domain-containing 3 (NLRP3) specific inhibitor MCC950, or extracellular high potassium concentration.	Potassium	171-180	caspase 1	Homo sapiens	13-22
33070272-3	2020	Since acid-base balance is closely linked to potassium metabolism, in the present work we aim to determine the effect of chronic metabolic acidosis (CMA) and hyperkalemia (HK) on protein abundance and localization of HCN3 in the rat kidney.	Potassium	45-54	hyperpolarization-activated cyclic nucleotide-gated potassium channel 3	Rattus norvegicus	217-221
33070272-12	2020	These findings further support HCN channels contribution to renal acid-base and potassium balance.	Potassium	80-89	cyclic nucleotide gated channel subunit alpha 1	Rattus norvegicus	31-34
33127441-5	2020	This impairment was abolished in the presence of voltage-gated potassium (KV1) channel blocker 4-aminopyridine, or by application of heparin-binding EGF-like growth factor (HB-EGF), which promotes KV1 channel down-regulations.	Potassium	63-72	heparin-binding EGF-like growth factor	Mus musculus	173-179
33328867-6	2020	In this review we propose that a residual fraction of functionally active Kir4.1 channels mediates a small, but continuous, efflux of potassium at the more depolarized RMP of GBM cells.	Potassium	134-143	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	74-80
25905305-1	2000	Aldosterone promotes active sodium transport and excretion of potassium via the mineralocorticoid receptor (MR) and the resultant activation of specific amiloride-sensitive sodium channels (ENaC) and the Na-K ATP ase pump in the target tissues.	Potassium	62-71	nuclear receptor subfamily 3 group C member 2	Homo sapiens	80-106
33237923-12	2020	Chromogranin A correlated significantly with potassium in patients with neuroendocrine tumors and there was a significant correlation between ACTH level and severity of hypokalemia.	Potassium	45-54	chromogranin A	Homo sapiens	0-14
25905305-1	2000	Aldosterone promotes active sodium transport and excretion of potassium via the mineralocorticoid receptor (MR) and the resultant activation of specific amiloride-sensitive sodium channels (ENaC) and the Na-K ATP ase pump in the target tissues.	Potassium	62-71	nuclear receptor subfamily 3 group C member 2	Homo sapiens	108-110
33237165-9	2020	The stages of NHL were: I (21%), II (18,4%), III (26,3%), and IV (34,2%), but KS were found only at III (40%) and IV (60%) stages.	Potassium	78-80	serpin family C member 1	Homo sapiens	97-103
33329012-3	2020	Due to the prevailing data suggesting that an increased potassium level is a main contributor, we studied the effect of a modulator of a big conductance Ca2+- and voltage-activated K+ channels (BK) modulator on contraction and relaxation of slow- and high-twitch muscle specimen before and after the pharmacological induction of myotonia.	Potassium	56-65	synaptotagmin XVII	Mus musculus	194-196
33228183-4	2020	We observed that the upregulated expression of cardiac gene markers (NKX2-5, MYH6, TNNT2, and DES) and cardiac ion channel genes (sodium, calcium, the potassium) also the increased levels of Connexin 43 and Nkx2.5 proteins.	Potassium	151-160	NK2 homeobox 5	Homo sapiens	69-75
33228183-4	2020	We observed that the upregulated expression of cardiac gene markers (NKX2-5, MYH6, TNNT2, and DES) and cardiac ion channel genes (sodium, calcium, the potassium) also the increased levels of Connexin 43 and Nkx2.5 proteins.	Potassium	151-160	myosin heavy chain 6	Homo sapiens	77-81
33228183-4	2020	We observed that the upregulated expression of cardiac gene markers (NKX2-5, MYH6, TNNT2, and DES) and cardiac ion channel genes (sodium, calcium, the potassium) also the increased levels of Connexin 43 and Nkx2.5 proteins.	Potassium	151-160	troponin T2, cardiac type	Homo sapiens	83-88
33228183-4	2020	We observed that the upregulated expression of cardiac gene markers (NKX2-5, MYH6, TNNT2, and DES) and cardiac ion channel genes (sodium, calcium, the potassium) also the increased levels of Connexin 43 and Nkx2.5 proteins.	Potassium	151-160	gap junction protein alpha 1	Homo sapiens	191-202
33228183-4	2020	We observed that the upregulated expression of cardiac gene markers (NKX2-5, MYH6, TNNT2, and DES) and cardiac ion channel genes (sodium, calcium, the potassium) also the increased levels of Connexin 43 and Nkx2.5 proteins.	Potassium	151-160	NK2 homeobox 5	Homo sapiens	207-213
33238639-3	2020	Meanwhile, Cs, Se, and Te were enriched in the phase separated potassium-rich materials on glass surface, which were extracted by water.	Potassium	63-72	squalene epoxidase	Homo sapiens	15-17
33238639-6	2020	The higher phase separation efficiency of potassium-rich materials led to the higher extraction efficiencies of Cs, Se, and Te in liquid Sb extraction than Bi.	Potassium	42-51	squalene epoxidase	Homo sapiens	116-118
33183317-4	2020	The effect of leptin relies on the down-regulation of the potassium/chloride extruder KCC2 activity and is present during a restricted period of postnatal development.	Potassium	58-67	leptin	Rattus norvegicus	14-20
33312183-7	2020	Compared to the other potassium treatments, the CRK x FA180 treatment increased the seed yield and net profit by 4.29-14.92% and 13.72-62.30%, respectively, over the 2 years.	Potassium	22-31	CRK proto-oncogene, adaptor protein	Homo sapiens	48-51
33312183-8	2020	The potassium agronomy efficiency and potassium recovery efficiency (KRE) of the CRK x FA180 treatment were also improved by 6.25-30.77% and 3.82-12.78% compared to those of the other potassium treatments.	Potassium	4-13	CRK proto-oncogene, adaptor protein	Homo sapiens	81-84
33312183-8	2020	The potassium agronomy efficiency and potassium recovery efficiency (KRE) of the CRK x FA180 treatment were also improved by 6.25-30.77% and 3.82-12.78% compared to those of the other potassium treatments.	Potassium	38-47	CRK proto-oncogene, adaptor protein	Homo sapiens	81-84
33312183-8	2020	The potassium agronomy efficiency and potassium recovery efficiency (KRE) of the CRK x FA180 treatment were also improved by 6.25-30.77% and 3.82-12.78% compared to those of the other potassium treatments.	Potassium	38-47	CRK proto-oncogene, adaptor protein	Homo sapiens	81-84
33312183-10	2020	The release period of CRK in the field during the growth period of cotton was longer than that detected by 25 C static water extraction, which increased the soil available potassium content and met the potassium demands over the whole cotton growth period.	Potassium	172-181	CRK proto-oncogene, adaptor protein	Homo sapiens	22-25
33312183-10	2020	The release period of CRK in the field during the growth period of cotton was longer than that detected by 25 C static water extraction, which increased the soil available potassium content and met the potassium demands over the whole cotton growth period.	Potassium	202-211	CRK proto-oncogene, adaptor protein	Homo sapiens	22-25
33007282-5	2020	The activity of the electrogenic isoform of the cardiac NBC (NBCe1) was estimated by recording intracellular pH under high potassium concentration and by measuring action potential duration (APD).	Potassium	123-132	solute carrier family 4 (anion exchanger), member 4	Mus musculus	61-66
33007282-7	2020	Additionally, the APD was shorter and the alkalization due to high extracellular potassium-induced depolarization was greater in this group, indicating that the NBCe1 was hyperactive.	Potassium	81-90	solute carrier family 4 (anion exchanger), member 4	Mus musculus	161-166
33183317-4	2020	The effect of leptin relies on the down-regulation of the potassium/chloride extruder KCC2 activity and is present during a restricted period of postnatal development.	Potassium	58-67	solute carrier family 12 member 5	Rattus norvegicus	86-90
33147278-1	2020	The human ether-a-go-go-related voltage-gated cardiac ion channel (commonly known as hERG) conducts the rapid outward repolarizing potassium current in cardiomyocytes (IKr).	Potassium	131-140	ETS transcription factor ERG	Homo sapiens	85-89
33135287-9	2020	In addition, the GSDMD pore results in potassium efflux that can activate the NLRP3 inflammasome.	Potassium	39-48	gasdermin D	Mus musculus	17-22
33135287-9	2020	In addition, the GSDMD pore results in potassium efflux that can activate the NLRP3 inflammasome.	Potassium	39-48	NLR family, pyrin domain containing 3	Mus musculus	78-83
33050989-3	2020	We found that potassium efflux is increased in TG-treated THP-1 macrophages and that the inhibition of potassium efflux blocks TG-induced cell death as well as caspase-1 and -2 activation.	Potassium	14-23	caspase 1	Homo sapiens	160-176
33016076-14	2020	CONCLUSION: Normal renal function was not associated with true hyperkalaemia, making the eGFR a useful tool in predicting true from pseudohyperkalaemia, especially for potassium results a$6.5 mmol/L.	Potassium	168-177	epidermal growth factor receptor	Homo sapiens	89-93
33050989-3	2020	We found that potassium efflux is increased in TG-treated THP-1 macrophages and that the inhibition of potassium efflux blocks TG-induced cell death as well as caspase-1 and -2 activation.	Potassium	103-112	caspase 1	Homo sapiens	160-176
33050989-4	2020	Furthermore, reducing ATP concentration (known to induce potassium efflux), restored cell viability and caspase-1 and -2 activity.	Potassium	57-66	caspase 1	Homo sapiens	104-120
33050989-7	2020	These results suggest that TG-induced THP-1 macrophage cell death is induced via pannexin-1 activation, which increases extracellular ATP, leading to an increase in potassium efflux.	Potassium	165-174	pannexin 1	Homo sapiens	81-91
32950535-1	2020	BACKGROUND: Long noncoding RNA potassium voltage-gated channel subfamily Q member 1 opposite strand/antisense transcript 1 (KCNQ1OT1) takes part in diabetic cataract progression.	Potassium	31-40	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	124-132
32745503-4	2020	The Ka/Ks ratio shows that cox1 has the slowest evolutionary rate.	Potassium	7-9	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	27-31
32798220-6	2020	We tested possible direct effects on GnRH neurons by altering voltage-gated potassium currents.	Potassium	76-85	gonadotropin releasing hormone 1	Mus musculus	37-41
32906212-2	2020	For one patient, a cognitively impaired adolescent with a de novo stop-gain VAMP2 mutation, we tested a potential treatment strategy, enhancing neurotransmission by prolonging action potentials with the aminopyridine family of potassium channel blockers, 4-aminopyridine and 3,4-diaminopyridine, in vitro and in vivo.	Potassium	227-236	vesicle associated membrane protein 2	Homo sapiens	76-81
33085076-7	2020	It was observed that subjects presenting an alteration of the gene responsible for the calcium channel, CACNA1S, presented lower serum potassium levels, own triggers and a higher proportion of subjects showing dyspnea during the crisis.	Potassium	135-144	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	104-111
32878973-3	2020	Here, we report the crystal structure of the Reduced Potassium Dependency3/Histone Deacetylase1 (RPD3/HDA1) type class II histone deacetylase HDA15 in Arabidopsis (Arabidopsis thaliana).	Potassium	53-62	histone deacetylase 15	Arabidopsis thaliana	142-147
32934003-8	2020	Our results also suggest that SBMA and ALS share common axonal excitability changes; increased nodal persistent sodium and reduced potassium currents that may accelerate motor neuronal death and differently affect axons-innervating different muscles.	Potassium	131-140	androgen receptor	Homo sapiens	30-34
32860887-1	2020	BACKGROUND: The hyperpolarizing activity of gamma-aminobutyric acid A (GABAA) receptors depends on the intracellular chloride gradient that is developmentally regulated by the activity of the chloride extruder potassium (K) chloride (Cl) cotransporter 2 (KCC2).	Potassium	210-219	solute carrier family 12 member 5	Rattus norvegicus	255-259
32878973-3	2020	Here, we report the crystal structure of the Reduced Potassium Dependency3/Histone Deacetylase1 (RPD3/HDA1) type class II histone deacetylase HDA15 in Arabidopsis (Arabidopsis thaliana).	Potassium	53-62	histone deacetylase 1	Arabidopsis thaliana	102-106
33079488-0	2020	Structural Engineering of SnS2 Encapsulated in Carbon Nanoboxes for High-Performance Sodium/Potassium-Ion Batteries Anodes.	Potassium	92-101	sodium voltage-gated channel alpha subunit 11	Homo sapiens	26-30
33121425-2	2021	Laboratory examination revealed that urinary potassium excretion and serum aldosterone level increased, at the same time with hyperthyroidism and thyroid related antibodies positive.Genetic testing showed that there was a complex heterozygous mutation in SLC12A3 gene ,c.1077C>G(p.N359K) and c.1567G>A(p.A523?	Potassium	45-54	solute carrier family 12 member 3	Homo sapiens	255-262
33127683-4	2020	Here, combining K2P2.1 (TREK-1) x-ray crystallography in different potassium concentrations, potassium anomalous scattering, molecular dynamics, and electrophysiology, we uncover unprecedented, asymmetric, potassium-dependent conformational changes that underlie K2P C-type gating.	Potassium	67-76	potassium two pore domain channel subfamily K member 2	Homo sapiens	16-22
33127683-4	2020	Here, combining K2P2.1 (TREK-1) x-ray crystallography in different potassium concentrations, potassium anomalous scattering, molecular dynamics, and electrophysiology, we uncover unprecedented, asymmetric, potassium-dependent conformational changes that underlie K2P C-type gating.	Potassium	67-76	potassium two pore domain channel subfamily K member 2	Homo sapiens	24-30
33127683-4	2020	Here, combining K2P2.1 (TREK-1) x-ray crystallography in different potassium concentrations, potassium anomalous scattering, molecular dynamics, and electrophysiology, we uncover unprecedented, asymmetric, potassium-dependent conformational changes that underlie K2P C-type gating.	Potassium	93-102	potassium two pore domain channel subfamily K member 2	Homo sapiens	16-22
33138194-4	2020	The chemically modified, bi-functional anti-EGFR Q-ASO and a 56-nt long EGFR mRNA fragment, in the presence of potassium ions, were shown to form in vitro very stable parallel G-quadruplex containing a 28-nt long external loop folding to two duplex-stem structure.	Potassium	111-120	epidermal growth factor receptor	Homo sapiens	44-48
33127683-4	2020	Here, combining K2P2.1 (TREK-1) x-ray crystallography in different potassium concentrations, potassium anomalous scattering, molecular dynamics, and electrophysiology, we uncover unprecedented, asymmetric, potassium-dependent conformational changes that underlie K2P C-type gating.	Potassium	93-102	potassium two pore domain channel subfamily K member 2	Homo sapiens	24-30
33127683-4	2020	Here, combining K2P2.1 (TREK-1) x-ray crystallography in different potassium concentrations, potassium anomalous scattering, molecular dynamics, and electrophysiology, we uncover unprecedented, asymmetric, potassium-dependent conformational changes that underlie K2P C-type gating.	Potassium	93-102	potassium two pore domain channel subfamily K member 2	Homo sapiens	16-22
33127683-4	2020	Here, combining K2P2.1 (TREK-1) x-ray crystallography in different potassium concentrations, potassium anomalous scattering, molecular dynamics, and electrophysiology, we uncover unprecedented, asymmetric, potassium-dependent conformational changes that underlie K2P C-type gating.	Potassium	93-102	potassium two pore domain channel subfamily K member 2	Homo sapiens	24-30
33138194-4	2020	The chemically modified, bi-functional anti-EGFR Q-ASO and a 56-nt long EGFR mRNA fragment, in the presence of potassium ions, were shown to form in vitro very stable parallel G-quadruplex containing a 28-nt long external loop folding to two duplex-stem structure.	Potassium	111-120	epidermal growth factor receptor	Homo sapiens	72-76
33122764-4	2020	Graft size, Kmax and Ks correlated with IHT/CCT and IGT/CCT in the KC group.	Potassium	21-23	CCT	Homo sapiens	44-47
33122764-4	2020	Graft size, Kmax and Ks correlated with IHT/CCT and IGT/CCT in the KC group.	Potassium	21-23	CCT	Homo sapiens	56-59
33192566-1	2020	Kv7.2 subunits encoded by the KCNQ2 gene constitute a critical molecular component of the M-current, a subthreshold voltage-gated potassium current controlling neuronal excitability by dampening repetitive action potential firing.	Potassium	130-139	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	0-5
32810596-7	2020	Ks correlated inversely with FIX and FV, thrombin-activatable fibrinolysis inhibitor, complement C1s, C7, C8, and apolipoprotein A-I.	Potassium	0-2	coagulation factor II, thrombin	Homo sapiens	41-49
32810596-7	2020	Ks correlated inversely with FIX and FV, thrombin-activatable fibrinolysis inhibitor, complement C1s, C7, C8, and apolipoprotein A-I.	Potassium	0-2	apolipoprotein A1	Homo sapiens	114-132
33192566-1	2020	Kv7.2 subunits encoded by the KCNQ2 gene constitute a critical molecular component of the M-current, a subthreshold voltage-gated potassium current controlling neuronal excitability by dampening repetitive action potential firing.	Potassium	130-139	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	30-35
33095786-14	2020	The most prominent of these was Hdac1 which may be regulating genes associated with glutamatergic signaling and potassium conductance.	Potassium	112-121	histone deacetylase 1	Mus musculus	32-37
32882214-2	2020	Although a previous report showed that quetiapine blocked hERG potassium current, quetiapine has been considered relatively safe in terms of cardiovascular side effects.	Potassium	63-72	ETS transcription factor ERG	Homo sapiens	58-62
33437698-3	2020	TPP is due to increased sodium/potassium ATPase activity during thyrotoxic states, which is due to mutations encoding potassium channels.	Potassium	31-40	dynein axonemal heavy chain 8	Homo sapiens	41-47
32882214-7	2020	Our results indicate that norquetiapine blocks hNav1.5 current in concentration-, state- and use-dependent manners, suggesting that the blockade of hNav1.5 current by norquetiapine may shorten the cardiac action potential duration and reduce the risk of QT interval prolongation induced by the inhibition of hERG potassium currents.	Potassium	313-322	sodium voltage-gated channel alpha subunit 5	Homo sapiens	47-54
32882214-7	2020	Our results indicate that norquetiapine blocks hNav1.5 current in concentration-, state- and use-dependent manners, suggesting that the blockade of hNav1.5 current by norquetiapine may shorten the cardiac action potential duration and reduce the risk of QT interval prolongation induced by the inhibition of hERG potassium currents.	Potassium	313-322	sodium voltage-gated channel alpha subunit 5	Homo sapiens	148-155
33057440-6	2020	Inhibition of COX-2 in vGPCR-transformed cells impairs vGPCR-driven angiogenesis and treatment with the COX-2-selective inhibitory drug Celecoxib produces a significant decrease in tumor growth, pointing to COX-2 activity as critical for vGPCR oncogenicity in vivo and indicating that COX-2-mediated angiogenesis could play a role in KS tumorigenesis.	Potassium	334-336	prostaglandin-endoperoxide synthase 2	Homo sapiens	104-109
33057440-6	2020	Inhibition of COX-2 in vGPCR-transformed cells impairs vGPCR-driven angiogenesis and treatment with the COX-2-selective inhibitory drug Celecoxib produces a significant decrease in tumor growth, pointing to COX-2 activity as critical for vGPCR oncogenicity in vivo and indicating that COX-2-mediated angiogenesis could play a role in KS tumorigenesis.	Potassium	334-336	prostaglandin-endoperoxide synthase 2	Homo sapiens	104-109
33057440-6	2020	Inhibition of COX-2 in vGPCR-transformed cells impairs vGPCR-driven angiogenesis and treatment with the COX-2-selective inhibitory drug Celecoxib produces a significant decrease in tumor growth, pointing to COX-2 activity as critical for vGPCR oncogenicity in vivo and indicating that COX-2-mediated angiogenesis could play a role in KS tumorigenesis.	Potassium	334-336	prostaglandin-endoperoxide synthase 2	Homo sapiens	104-109
33057440-7	2020	These results, along with the overexpression of COX-2 in KS lesions, define COX-2 as a potential target for the prevention and treatment of KSHV-oncogenesis.	Potassium	57-59	prostaglandin-endoperoxide synthase 2	Homo sapiens	48-53
33057440-7	2020	These results, along with the overexpression of COX-2 in KS lesions, define COX-2 as a potential target for the prevention and treatment of KSHV-oncogenesis.	Potassium	57-59	prostaglandin-endoperoxide synthase 2	Homo sapiens	76-81
33057457-9	2020	In keeping with functional data, the presence of both TREK-1 and Kir6.1 (potassium selective), as well as TRPM4, TRPV4 and TRPC6 (cationic non-selective) channels was confirmed in VIC at the protein level.	Potassium	73-82	potassium inwardly rectifying channel subfamily J member 8	Homo sapiens	65-71
33163493-5	2020	Ubiquitous knockdown of CG4928 causes flies to have a reduced secretion rate from the Malpighian tubules; altering potassium content in the body and in the Malpighian tubules, homologous to the renal system; and results in the development of edema.	Potassium	115-124	uncharacterized protein	Drosophila melanogaster	24-30
32736087-0	2020	5-HT7 receptors increase the excitability of hippocampal CA1 pyramidal neurons by inhibiting the A-type potassium current.	Potassium	104-113	carbonic anhydrase 1	Rattus norvegicus	57-60
32788210-3	2020	In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast Saccharomyces cerevisiae We found that potassium-dependent autophagy requires the core pathway kinases Atg1, Atg5, Vps34, as well as other components of the phosphatidylinositol 3-kinase complex.	Potassium	73-82	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	251-255
32840624-7	2020	The most significant locus was rs77958157 near cocaine- and amphetamine-regulated transcript prepropeptide (CARTPT) , a gene involved in eating behavior and appetite regulation (P = 2.3 x 10-8 with sodium-to-potassium ratio).	Potassium	208-217	CART prepropeptide	Homo sapiens	47-106
32840624-7	2020	The most significant locus was rs77958157 near cocaine- and amphetamine-regulated transcript prepropeptide (CARTPT) , a gene involved in eating behavior and appetite regulation (P = 2.3 x 10-8 with sodium-to-potassium ratio).	Potassium	208-217	CART prepropeptide	Homo sapiens	108-114
32840624-8	2020	Two suggestive loci were replicated in additional samples: for sodium excretion, rs12094702 near zinc finger SWIM-type containing 5 (ZSWIM5) was replicated in the Asian ancestry sample reaching Bonferroni-corrected significance (P = 0.007), and for potassium excretion rs34473523 near sodium leak channel (NALCN) was associated at a nominal P value with potassium excretion both in European (P = 0.043) and African (P = 0.043) ancestry cohorts.	Potassium	249-258	zinc finger SWIM-type containing 5	Homo sapiens	97-131
32840624-8	2020	Two suggestive loci were replicated in additional samples: for sodium excretion, rs12094702 near zinc finger SWIM-type containing 5 (ZSWIM5) was replicated in the Asian ancestry sample reaching Bonferroni-corrected significance (P = 0.007), and for potassium excretion rs34473523 near sodium leak channel (NALCN) was associated at a nominal P value with potassium excretion both in European (P = 0.043) and African (P = 0.043) ancestry cohorts.	Potassium	249-258	zinc finger SWIM-type containing 5	Homo sapiens	133-139
32840624-8	2020	Two suggestive loci were replicated in additional samples: for sodium excretion, rs12094702 near zinc finger SWIM-type containing 5 (ZSWIM5) was replicated in the Asian ancestry sample reaching Bonferroni-corrected significance (P = 0.007), and for potassium excretion rs34473523 near sodium leak channel (NALCN) was associated at a nominal P value with potassium excretion both in European (P = 0.043) and African (P = 0.043) ancestry cohorts.	Potassium	354-363	zinc finger SWIM-type containing 5	Homo sapiens	97-131
32840624-8	2020	Two suggestive loci were replicated in additional samples: for sodium excretion, rs12094702 near zinc finger SWIM-type containing 5 (ZSWIM5) was replicated in the Asian ancestry sample reaching Bonferroni-corrected significance (P = 0.007), and for potassium excretion rs34473523 near sodium leak channel (NALCN) was associated at a nominal P value with potassium excretion both in European (P = 0.043) and African (P = 0.043) ancestry cohorts.	Potassium	354-363	zinc finger SWIM-type containing 5	Homo sapiens	133-139
32788210-3	2020	In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast Saccharomyces cerevisiae We found that potassium-dependent autophagy requires the core pathway kinases Atg1, Atg5, Vps34, as well as other components of the phosphatidylinositol 3-kinase complex.	Potassium	73-82	Atg5p	Saccharomyces cerevisiae S288C	257-261
32788210-3	2020	In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast Saccharomyces cerevisiae We found that potassium-dependent autophagy requires the core pathway kinases Atg1, Atg5, Vps34, as well as other components of the phosphatidylinositol 3-kinase complex.	Potassium	73-82	phosphatidylinositol 3-kinase VPS34	Saccharomyces cerevisiae S288C	263-268
32788210-3	2020	In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast Saccharomyces cerevisiae We found that potassium-dependent autophagy requires the core pathway kinases Atg1, Atg5, Vps34, as well as other components of the phosphatidylinositol 3-kinase complex.	Potassium	187-196	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	251-255
32788210-3	2020	In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast Saccharomyces cerevisiae We found that potassium-dependent autophagy requires the core pathway kinases Atg1, Atg5, Vps34, as well as other components of the phosphatidylinositol 3-kinase complex.	Potassium	187-196	Atg5p	Saccharomyces cerevisiae S288C	257-261
32788210-3	2020	In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast Saccharomyces cerevisiae We found that potassium-dependent autophagy requires the core pathway kinases Atg1, Atg5, Vps34, as well as other components of the phosphatidylinositol 3-kinase complex.	Potassium	187-196	phosphatidylinositol 3-kinase VPS34	Saccharomyces cerevisiae S288C	263-268
33841871-5	2021	In situ genetic studies revealed a gain-of-function KCNJ5 mutation within an aldosterone-producing adenoma that was clinically responsive to changes in extracellular potassium.	Potassium	166-175	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	52-57
32865974-2	2020	Here, we use G protein-coupled inward rectifier potassium (GIRK) channel activation in Xenopus oocytes to measure the kinetics of D2R antagonism by a series of aripiprazole analogues, as well as the recovery of dopamine (DA) responsivity upon washout.	Potassium	48-57	potassium inwardly rectifying channel subfamily J member 3 S homeolog	Xenopus laevis	59-63
32865974-2	2020	Here, we use G protein-coupled inward rectifier potassium (GIRK) channel activation in Xenopus oocytes to measure the kinetics of D2R antagonism by a series of aripiprazole analogues, as well as the recovery of dopamine (DA) responsivity upon washout.	Potassium	48-57	dopamine receptor D2 L homeolog	Xenopus laevis	130-133
33305731-2	2020	Recently, vonoprazan, a novel potassium-competitive acid blocker (P-CAB), has been introduced as more effective treatment option.	Potassium	30-39	neural proliferation, differentiation and control 1	Homo sapiens	68-71
32830538-1	2020	Acyl-CoA synthetase medium-chain family member 2 (Acsm2) gene was first identified and cloned by our group as a kidney-specific "KS" gene.	Potassium	129-131	acyl-CoA synthetase medium-chain family member 2	Mus musculus	0-48
32830538-1	2020	Acyl-CoA synthetase medium-chain family member 2 (Acsm2) gene was first identified and cloned by our group as a kidney-specific "KS" gene.	Potassium	129-131	acyl-CoA synthetase medium-chain family member 2	Mus musculus	50-55
32765863-1	2020	Hypokalemic periodic paralysis type 1 (OMIM; HOKPP1) and type 2 (OMIM; HOKPP2) are diseases of the muscle characterized by episodes of painless muscle weakness, and is associated with low potassium blood levels.	Potassium	188-197	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	45-51
32765863-1	2020	Hypokalemic periodic paralysis type 1 (OMIM; HOKPP1) and type 2 (OMIM; HOKPP2) are diseases of the muscle characterized by episodes of painless muscle weakness, and is associated with low potassium blood levels.	Potassium	188-197	sodium voltage-gated channel alpha subunit 4	Homo sapiens	71-77
32726456-9	2020	CONCLUSIONS AND IMPLICATIONS: Kir4.1 channels are also target of aminoglycoside antibiotics, which could affect potassium transport in several tissues.	Potassium	112-121	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	30-36
32798904-0	2020	Target of rapamycin regulates potassium uptake in Arabidopsis and potato.	Potassium	30-39	target of rapamycin	Arabidopsis thaliana	0-19
32798904-4	2020	However, it is still unclear whether there is a causative link between the TOR pathway and potassium absorption.	Potassium	91-100	target of rapamycin	Arabidopsis thaliana	75-78
32798904-5	2020	Here, we show that the expression of some potassium transporters and channels was regulated by TOR, and the suppression of TOR activity significantly affected potassium uptake in Arabidopsis and potato.	Potassium	42-51	target of rapamycin	Arabidopsis thaliana	95-98
32798904-5	2020	Here, we show that the expression of some potassium transporters and channels was regulated by TOR, and the suppression of TOR activity significantly affected potassium uptake in Arabidopsis and potato.	Potassium	42-51	target of rapamycin	Arabidopsis thaliana	123-126
32798904-9	2020	In addition, the overexpression of CIPK23 could effectively restore the defects in growth and potassium uptake induced by the TOR inhibitors.	Potassium	94-103	CBL-interacting protein kinase 23	Arabidopsis thaliana	35-41
32798904-9	2020	In addition, the overexpression of CIPK23 could effectively restore the defects in growth and potassium uptake induced by the TOR inhibitors.	Potassium	94-103	target of rapamycin	Arabidopsis thaliana	126-129
32798904-10	2020	Thus, our work reveals a link between TOR signaling and CIPK23 and provides new insight into the regulation of potassium uptake in plants.	Potassium	111-120	target of rapamycin	Arabidopsis thaliana	38-41
32798904-10	2020	Thus, our work reveals a link between TOR signaling and CIPK23 and provides new insight into the regulation of potassium uptake in plants.	Potassium	111-120	CBL-interacting protein kinase 23	Arabidopsis thaliana	56-62
32999428-6	2020	CBD inhibited hERG potassium channels with an IC50 value of 2.07 microM at room temperature and delayed rectifier potassium current with 6.5 microM at 37  C, respectively.	Potassium	19-28	ETS transcription factor ERG	Homo sapiens	14-18
32870280-3	2020	In this study, we characterise the G4 formation of a (GGN)13 repeat found within the 5" UTR of the potassium 2-pore domain leak channel Task3 mRNA.	Potassium	99-108	gametogenetin	Homo sapiens	54-57
32870280-4	2020	Biophysical analyses show that this (GGN)13 repeat forms a parallel G4 in vitro exhibiting the stereotypical potassium specificity of G4s, remaining thermostable under physiological ionic conditions.	Potassium	109-118	gametogenetin	Homo sapiens	37-40
32842723-3	2020	The synergism in structural and chemical framework, along with open-ended morphology, enables bifunctionality of hard-carbon NCF as symmetric adsorptive electrodes for supercapacitors and intercalation anodes for hybrid potassium ion capacitors (KICs).	Potassium	220-229	neutrophil cytosolic factor 4	Homo sapiens	125-128
32946686-11	2020	Furthermore, it was shown by voltage clamp measurement that this mechanism inactivates the voltage-dependent potassium current and simultaneously generates photo-activated CS molecule induced (PACS) current owing to the loss of the cell membrane capacitance.	Potassium	109-118	citrate synthase	Rattus norvegicus	172-174
32973172-1	2020	Na+-K+-2Cl- Cotransporter (NKCC1) is a protein that aids in the active transport of sodium, potassium, and chloride ions across cell membranes.	Potassium	92-101	solute carrier family 12 member 2	Homo sapiens	27-32
32629001-5	2020	In addition, the prolongation of the corrected QT (QTc) interval under CMUS that increased vulnerability to VAs was significantly attenuated by stimulation of S1R due to the decreased amplitude of L-type calcium current (ICa-L) and the restoration of reduced transient outward potassium current (Ito) resulting from CMUS induction.	Potassium	277-286	sigma non-opioid intracellular receptor 1	Rattus norvegicus	159-162
32449816-1	2020	It was anticipated that the potassium reagent RK (R = CH(SiMe3)2 or N(SiMe3)2) reacts with the low-valent Al(I) complex (DIPPBDI)Al (DIPPBDI = HC[C(Me)N(DIPP)]2, DIPP = 2,6-iPr-phenyl) to the anionic Al complex [(DIPPBDI)AlR]-K+.	Potassium	28-37	nudix hydrolase 4	Homo sapiens	162-170
32912155-8	2020	The selection pressure estimation (Ka/Ks ratios) of genes in the Chrysosplenium species showed that matK and ycf2 were subjected to positive selection.	Potassium	38-40	megakaryocyte-associated tyrosine kinase	Homo sapiens	100-104
32506135-11	2020	CONCLUSIONS: Potassium supplementation led to a decrease in FGF23, which was accompanied by increase in plasma phosphate and decreased calcium excretion.	Potassium	13-22	fibroblast growth factor 23	Homo sapiens	60-65
32936716-3	2020	However, the role and molecular mechanism of potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) in HCC are still unclear.	Potassium	45-54	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	124-132
33004801-5	2020	Mechanistically, BAFF activated NLRP3 inflammasomes by promoting the association of cIAP-TRAF2 with components of NLRP3 inflammasomes, and by inducing Src activity-dependent ROS production and potassium ion efflux.	Potassium	193-202	TNF superfamily member 13b	Homo sapiens	17-21
33004801-5	2020	Mechanistically, BAFF activated NLRP3 inflammasomes by promoting the association of cIAP-TRAF2 with components of NLRP3 inflammasomes, and by inducing Src activity-dependent ROS production and potassium ion efflux.	Potassium	193-202	NLR family pyrin domain containing 3	Homo sapiens	32-37
32506135-13	2020	Our results indicate distinct effects of potassium and sodium intake on bone mineral parameters, including FGF23.	Potassium	41-50	fibroblast growth factor 23	Homo sapiens	107-112
32835124-7	2020	Additionally, Furin intracellular levels are largely dependent on concentration of intracellular ions, notably sodium, potassium, and magnesium.	Potassium	119-128	furin, paired basic amino acid cleaving enzyme	Homo sapiens	14-19
32541000-0	2020	Kir2.1 interactome mapping uncovers PKP4 as a modulator of the Kir2.1-regulated inward rectifier potassium currents.	Potassium	97-106	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	0-6
32541000-0	2020	Kir2.1 interactome mapping uncovers PKP4 as a modulator of the Kir2.1-regulated inward rectifier potassium currents.	Potassium	97-106	plakophilin 4	Homo sapiens	36-40
32541000-0	2020	Kir2.1 interactome mapping uncovers PKP4 as a modulator of the Kir2.1-regulated inward rectifier potassium currents.	Potassium	97-106	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	63-69
32541000-3	2020	Understanding the molecular mechanisms that govern the regulation of inward rectifier potassium currents by Kir2.1 in both normal and disease contexts should help uncover novel targets for therapeutic intervention in ATS1 and other Kir2.1-associated channelopathies.	Potassium	86-95	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	108-114
32541000-3	2020	Understanding the molecular mechanisms that govern the regulation of inward rectifier potassium currents by Kir2.1 in both normal and disease contexts should help uncover novel targets for therapeutic intervention in ATS1 and other Kir2.1-associated channelopathies.	Potassium	86-95	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	232-238
32541000-8	2020	Finally, using patch-clamp analysis, we validate the functional relevance of PKP4, one of our top BioID interactors, to the modulation of Kir2.1-controlled inward rectifier potassium currents.Our results validate the power of our BioID approach in identifying functionally relevant Kir2.1interactors and underline the value of our Kir2.1 interactome as a repository for numerous novel biological hypotheseson Kir2.1 and Kir2.1-associated diseases.	Potassium	173-182	plakophilin 4	Homo sapiens	77-81
32541000-8	2020	Finally, using patch-clamp analysis, we validate the functional relevance of PKP4, one of our top BioID interactors, to the modulation of Kir2.1-controlled inward rectifier potassium currents.Our results validate the power of our BioID approach in identifying functionally relevant Kir2.1interactors and underline the value of our Kir2.1 interactome as a repository for numerous novel biological hypotheseson Kir2.1 and Kir2.1-associated diseases.	Potassium	173-182	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	138-144
32353862-8	2020	Ex vivo electrophysiological recordings show that nesfatin-1 hyperpolarizes dopamine, but not GABA, neurons of the VTA by inducing an outward potassium current.	Potassium	142-151	nucleobindin 2	Homo sapiens	50-60
32716363-5	2020	beta-Glucan acted upstream of the NLRP3 inflammasome by preventing potassium (K+) efflux, mitochondrial ROS (mtROS) generation, and, ultimately, apoptosis-associated speck-like protein containing a CARD (ASC) oligomerization and speck formation.	Potassium	67-76	NLR family pyrin domain containing 3	Homo sapiens	34-39
32923723-9	2020	MMP-8 correlated inversely with pyridoxine (r = -0.321, P = 0.002) and potassium (r = -0.220, P = 0.033).	Potassium	71-80	matrix metallopeptidase 8	Homo sapiens	0-5
32867854-14	2020	In addition, substitution of the two amino acids (KS) from nsp1 of SARS-CoV was previously reported to revert loss of interferon-alpha expression.	Potassium	50-52	SH2 domain containing 3A	Homo sapiens	59-63
32847923-2	2020	In the emergency room (ER), interventions aim to protect patients from the immediate dangers of elevated serum potassium by redistributing potassium ions from the bloodstream into the cells via intravenous insulin or nebulised beta2-agonists.	Potassium	111-120	insulin	Homo sapiens	206-213
32861249-2	2020	Insulin sensitivity and metabolic acidosis are associated with muscle wasting and may be improved with potassium intake.	Potassium	103-112	insulin	Homo sapiens	0-7
32847923-2	2020	In the emergency room (ER), interventions aim to protect patients from the immediate dangers of elevated serum potassium by redistributing potassium ions from the bloodstream into the cells via intravenous insulin or nebulised beta2-agonists.	Potassium	111-120	ATPase H+ transporting V0 subunit a2	Homo sapiens	227-232
32634531-5	2020	These features were mimicked by pharmacologically blocking the fast-inactivating A-type potassium current and matched well with the higher concentrations of Kv4.2 and Kv4.3 and the lower concentrations of BK and Kv1.2 channels detected by Western blotting.	Potassium	88-97	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	157-162
32641496-1	2020	Two-pore domain potassium channels (K2P) are the major determinants of the background potassium conductance.	Potassium	16-25	keratin 76	Homo sapiens	36-39
32641496-4	2020	The K2P channel subunits TRESK and TREK-2 provide the predominant background potassium current in the primary sensory neurons of the dorsal root and trigeminal ganglia.	Potassium	77-86	keratin 76	Homo sapiens	4-7
32641496-4	2020	The K2P channel subunits TRESK and TREK-2 provide the predominant background potassium current in the primary sensory neurons of the dorsal root and trigeminal ganglia.	Potassium	77-86	potassium two pore domain channel subfamily K member 18	Homo sapiens	25-30
32641496-4	2020	The K2P channel subunits TRESK and TREK-2 provide the predominant background potassium current in the primary sensory neurons of the dorsal root and trigeminal ganglia.	Potassium	77-86	potassium two pore domain channel subfamily K member 10	Homo sapiens	35-41
32634531-5	2020	These features were mimicked by pharmacologically blocking the fast-inactivating A-type potassium current and matched well with the higher concentrations of Kv4.2 and Kv4.3 and the lower concentrations of BK and Kv1.2 channels detected by Western blotting.	Potassium	88-97	potassium voltage-gated channel subfamily D member 3	Rattus norvegicus	167-172
32789612-4	2020	RECENT FINDINGS: Although the distal convoluted tubule (DCT) is a short part of the nephron that reabsorbs salt, via the sodium-chloride cotransporter (NCC), it is highly sensitive to changes in plasma potassium concentration.	Potassium	202-211	solute carrier family 12 member 3	Homo sapiens	152-155
32702990-3	2020	To better understand Kir channel activation, we target multiple mutants of the Kir channel KirBac1.1 via solid state Nuclear Magnetic Resonance (SSNMR) spectroscopy, potassium efflux assays, and Forster-resonance-energy-transfer (FRET) measurements.	Potassium	166-175	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	79-82
32611790-2	2020	The H+/ K+-ATPase (HKA), which is comprised of the HKalpha1 (gene: atp4a) and HKbeta (gene: atp4b) subunits, has an established role in potassium and acid-base regulation in mammals and is well known for its role in gastric acidification.	Potassium	136-145	potassium-transporting ATPase alpha chain 1	Oreochromis niloticus	67-72
32611790-2	2020	The H+/ K+-ATPase (HKA), which is comprised of the HKalpha1 (gene: atp4a) and HKbeta (gene: atp4b) subunits, has an established role in potassium and acid-base regulation in mammals and is well known for its role in gastric acidification.	Potassium	136-145	potassium-transporting ATPase subunit beta	Oreochromis niloticus	92-97
32789612-7	2020	High-potassium diet targets NCC in the DCT, resulting in natriuresis and fluid volume reduction, which are protective from hypertension and other cardiovascular problems.	Potassium	5-14	solute carrier family 12 member 3	Homo sapiens	28-31
32590038-2	2020	Inwardly rectifying potassium (Kir) channels, and specifically KIR4.1, have a predominant role in K+ homeostasis and their involvement in neuronal excitability control have been hypothesized.	Potassium	20-29	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	63-69
31919958-0	2020	Cardiovascular risk associated with serum potassium in the context of mineralocorticoid receptor antagonist use in patients with heart failure and left ventricular dysfunction.	Potassium	42-51	nuclear receptor subfamily 3 group C member 2	Homo sapiens	70-96
32903427-3	2020	While activation of the sodium-potassium-ATPase (NKA) in response to an elevation of extracellular K+ may decrease intracellular Na+, the cotransport of transmitters, such as glutamate, together with Na+ results in an increase in astrocytic Na+.	Potassium	31-40	tachykinin precursor 1	Homo sapiens	49-52
31671245-5	2020	Indeed, AMPK activators inhibit endothelium-dependent hyperpolarization (EDH) type relaxations in superior mesenteric arteries, partly by inhibiting endothelial calcium-activated potassium channels signalling.	Potassium	179-188	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	8-12
32856786-6	2020	A TBDMS-beta-CD derivative with a p-tolyl substituent has a remarkable chiral selectivity for the (S)-1-(1-naphthyl)ethylamine over the corresponding (R)-isomer (KS /KR =4.1+-0.5), whereas a TBDMS-beta-CD derivative with a 2-picolyl substituent shows the inverse chiral selectivity (KR /KS =8.7+-0.6).	Potassium	162-164	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	8-15
32856786-6	2020	A TBDMS-beta-CD derivative with a p-tolyl substituent has a remarkable chiral selectivity for the (S)-1-(1-naphthyl)ethylamine over the corresponding (R)-isomer (KS /KR =4.1+-0.5), whereas a TBDMS-beta-CD derivative with a 2-picolyl substituent shows the inverse chiral selectivity (KR /KS =8.7+-0.6).	Potassium	162-164	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	197-204
32856786-6	2020	A TBDMS-beta-CD derivative with a p-tolyl substituent has a remarkable chiral selectivity for the (S)-1-(1-naphthyl)ethylamine over the corresponding (R)-isomer (KS /KR =4.1+-0.5), whereas a TBDMS-beta-CD derivative with a 2-picolyl substituent shows the inverse chiral selectivity (KR /KS =8.7+-0.6).	Potassium	287-289	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	8-15
32856786-6	2020	A TBDMS-beta-CD derivative with a p-tolyl substituent has a remarkable chiral selectivity for the (S)-1-(1-naphthyl)ethylamine over the corresponding (R)-isomer (KS /KR =4.1+-0.5), whereas a TBDMS-beta-CD derivative with a 2-picolyl substituent shows the inverse chiral selectivity (KR /KS =8.7+-0.6).	Potassium	287-289	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	197-204
32407847-8	2020	KEY FINDINGS: The results showed that the TR and/or HES treatment significantly suppressed CCl4 induced rise of urea, uric acid, potassium, and follicle-stimulating hormone levels.	Potassium	129-138	C-C motif chemokine ligand 4	Rattus norvegicus	91-95
32742012-13	2020	Similar decreases in serum potassium were noted following IV regular insulin administration.	Potassium	27-36	insulin	Homo sapiens	69-76
31496375-1	2020	Study of seven new guanidiniocarbonylpyrrole (GCP) - fluorophore conjugates interactions with dipeptidyl peptidase III (DPP III) showed that all compounds bind strongly (Ks   microM) to enzyme active site, but with very different fluorimetric response (varying from quenching to strong increase), dependent on the fluorophore type and intramolecular pre-organisation of molecule.	Potassium	170-172	dipeptidyl peptidase 3	Homo sapiens	94-118
31496375-1	2020	Study of seven new guanidiniocarbonylpyrrole (GCP) - fluorophore conjugates interactions with dipeptidyl peptidase III (DPP III) showed that all compounds bind strongly (Ks   microM) to enzyme active site, but with very different fluorimetric response (varying from quenching to strong increase), dependent on the fluorophore type and intramolecular pre-organisation of molecule.	Potassium	170-172	dipeptidyl peptidase 3	Homo sapiens	120-127
33214341-0	2020	Potassium-dependent sodium/calcium exchanger 3 (Nckx3) depletion leads to abnormal motor function and social behavior in mice.	Potassium	0-9	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	48-53
33214341-3	2020	Nckx3, a potassium-dependent Na+/Ca2+ exchanger, is most abundant in the brain and has a critical role in the transport of intracellular calcium across the cell membrane.	Potassium	9-18	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	0-5
32576659-5	2020	Using a panel of reporter assays in reconstituted HEK293T/17 cells, we found that GPR139 functions via the Gq/11 pathway and thereby distinctly regulates cellular effector systems, including stimulation of cAMP production and inhibition of G protein inward rectifying potassium (GIRK) channels.	Potassium	268-277	G protein-coupled receptor 139	Homo sapiens	82-88
33040821-16	2020	Low-dose insulin combined with electrolyte supplementation is effective in the treatment of DKA in children, which can effectively control blood sugar, sodium, potassium level, and inflammatory factor concentration.	Potassium	160-169	insulin	Homo sapiens	9-16
31732108-7	2020	Further supporting the involvement of potassium currents, we observed an overexpression of KCNC1 and KCNC2 in hippocampal neurons derived from lithium responders.	Potassium	38-47	potassium voltage-gated channel subfamily C member 1	Homo sapiens	91-96
32727346-5	2020	RESULTS: On slice electrophysiology, LC-NE neurons of Ndntm1ky mice with necdin deficiency showed significantly decreased spontaneous activities and impaired excitability, which was mediated by enhanced A-type voltage-dependent potassium currents.	Potassium	228-237	necdin, MAGE family member	Mus musculus	73-79
32720790-6	2021	Besides, the expression levels of potassium voltage-gated channel subfamily Q member 1 opposite strand 1 (KCNQ1OT1) and microRNA-340-5p (miR-340-5p) were determined by quantitative real-time polymerase chain reaction (qRT-PCR).	Potassium	34-43	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	106-114
32702863-19	2020	Moreover, the patients with only 1 SLC12A3 mutant allele should pay regular attention to blood potassium and glucose levels.	Potassium	95-104	solute carrier family 12 member 3	Homo sapiens	35-42
31732108-7	2020	Further supporting the involvement of potassium currents, we observed an overexpression of KCNC1 and KCNC2 in hippocampal neurons derived from lithium responders.	Potassium	38-47	potassium voltage-gated channel subfamily C member 2	Homo sapiens	101-106
32818118-3	2020	Up to 35% of healthy individuals below 25 years of age, trained athletes, and those with a rare form of the familial syndrome with potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) mutation may have asymptomatic sinus bradycardia without any heart diseases.	Potassium	131-140	hyperpolarization activated cyclic nucleotide gated potassium channel 4	Homo sapiens	148-209
32818118-3	2020	Up to 35% of healthy individuals below 25 years of age, trained athletes, and those with a rare form of the familial syndrome with potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) mutation may have asymptomatic sinus bradycardia without any heart diseases.	Potassium	131-140	hyperpolarization activated cyclic nucleotide gated potassium channel 4	Homo sapiens	211-215
31598634-10	2020	CONCLUSION: We demonstrated a high vulnerability to tachycardia of optically tachypaced hiPSC-CMs in EHT and the effective termination by ryanodine receptor stabilization, sodium or hERG potassium channel inhibition.	Potassium	187-196	ETS transcription factor ERG	Homo sapiens	182-186
32645929-4	2020	Pulmonary sodium-potassium-chloride co-transporter 1 (NKCC1) regulates the net influx of ions and water into alveolar cells.	Potassium	17-26	solute carrier family 12 member 2	Homo sapiens	54-59
32714200-11	2020	A high-potassium diet significantly increased BK protein abundance and SPAK phosphorylation levels, while reducing ERK1/2 phosphorylation levels.	Potassium	7-16	serine/threonine kinase 39	Mus musculus	71-75
32714200-11	2020	A high-potassium diet significantly increased BK protein abundance and SPAK phosphorylation levels, while reducing ERK1/2 phosphorylation levels.	Potassium	7-16	mitogen-activated protein kinase 3	Mus musculus	115-121
32353421-0	2020	NEK7 mediated assembly and activation of NLRP3 inflammasome downstream of potassium efflux in ventilator-induced lung injury.	Potassium	74-83	NIMA (never in mitosis gene a)-related expressed kinase 7	Mus musculus	0-4
32353421-0	2020	NEK7 mediated assembly and activation of NLRP3 inflammasome downstream of potassium efflux in ventilator-induced lung injury.	Potassium	74-83	NLR family, pyrin domain containing 3	Mus musculus	41-46
32353421-7	2020	Mechanical stretch exaggerated the interaction between NEK7 and NLRP3, leading to assembly and activation of NLRP3 inflammasome downstream of potassium efflux.	Potassium	142-151	NIMA (never in mitosis gene a)-related expressed kinase 7	Mus musculus	55-59
32353421-7	2020	Mechanical stretch exaggerated the interaction between NEK7 and NLRP3, leading to assembly and activation of NLRP3 inflammasome downstream of potassium efflux.	Potassium	142-151	NLR family, pyrin domain containing 3	Mus musculus	64-69
32353421-7	2020	Mechanical stretch exaggerated the interaction between NEK7 and NLRP3, leading to assembly and activation of NLRP3 inflammasome downstream of potassium efflux.	Potassium	142-151	NLR family, pyrin domain containing 3	Mus musculus	109-114
31907393-9	2020	The lysine residues (K51 and K68) are essential for ubiquitination and proteasomal degradation of ERRalpha by CA.	Potassium	29-32	estrogen related receptor alpha	Homo sapiens	98-106
32068308-1	2020	Kir4.1, a glial-specific inwardly rectifying potassium channel, is implicated in astrocytic maintenance of K+ homeostasis.	Potassium	45-54	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	0-6
31898359-8	2020	The expression of cardiomyocytes genes MYH6, TNNT2, DES together with ion channels genes of the heart (sodium, calcium, and potassium) decreased in p31/33 induced AF-MSCs.	Potassium	124-133	ATPase H+ transporting V1 subunit E1	Homo sapiens	148-151
32703555-0	2020	Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol.	Potassium	54-63	ETS transcription factor ERG	Homo sapiens	48-52
32703555-3	2020	Their hypothesis was that soestalol, but not the acid metabolite, would inhibit the hERG potassium current.	Potassium	89-98	ETS transcription factor ERG	Homo sapiens	84-88
31865509-0	2020	The topology of plastid inner envelope potassium cation efflux antiporter KEA1 provides new insights into its regulatory features.	Potassium	39-48	K+ efflux antiporter 1	Arabidopsis thaliana	74-78
32360664-8	2020	Other cell-type specific processes altered in SOD1 mutant brainstem include those from motor neurons (axon regeneration, voltage-gated sodium and potassium channels underlying excitability, potassium ion transport), trigeminal sensory neurons (detection of temperature stimulus involved in sensory perception), and cellular response to toxic substances (uncharacterized cell populations).	Potassium	146-155	superoxide dismutase 1, soluble	Mus musculus	46-50
32045575-7	2020	Since DC shift is commonly associated to a rise in extracellular potassium, potassium homeostasis regulated by Kir4.1 channels in astrocytes may play an key role at seizure onset.	Potassium	65-74	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	111-117
32045575-7	2020	Since DC shift is commonly associated to a rise in extracellular potassium, potassium homeostasis regulated by Kir4.1 channels in astrocytes may play an key role at seizure onset.	Potassium	76-85	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	111-117
32625100-13	2020	High potassium intake decreased angiotensin converting enzyme 2 gene expression and protein levels (P < 0.01).No morphological abnormalities were observed in renal tissue during high potassium diet.The reduced expression of angiotensin-I converting enzyme, renin, and angiotensin converting enzyme 2 during potassium supplementation suggest that high dietary potassium intake could modulate these vasoactive enzymes and this effects can contribute to the preventive and antihypertensive effect of potassium.	Potassium	5-14	angiotensin I converting enzyme 2	Rattus norvegicus	268-299
32209376-3	2020	In this study, the effects of KS on AKR1C3 inhibition and anti-proliferative activities were investigated in the hormone-dependent MCF-7 breast cancer cells.	Potassium	30-32	aldo-keto reductase family 1 member C3	Homo sapiens	36-42
32209376-4	2020	We identified that KS arrested the enzymatic conversion of estrone to 17-beta estradiol, by inhibiting AKR1C3 in intact MCF-7 cells.	Potassium	19-21	aldo-keto reductase family 1 member C3	Homo sapiens	103-109
32209376-8	2020	Molecular docking studies performed to understand the inhibition mechanism of KS on AKR1C3 revealed that KS occupied the binding region of AKR1C3 with almost similar orientation as indomethacin (IM), thereby acting as an antagonistic agent for AKR1C3.	Potassium	78-80	aldo-keto reductase family 1 member C3	Homo sapiens	84-90
32209376-8	2020	Molecular docking studies performed to understand the inhibition mechanism of KS on AKR1C3 revealed that KS occupied the binding region of AKR1C3 with almost similar orientation as indomethacin (IM), thereby acting as an antagonistic agent for AKR1C3.	Potassium	78-80	aldo-keto reductase family 1 member C3	Homo sapiens	139-145
32209376-8	2020	Molecular docking studies performed to understand the inhibition mechanism of KS on AKR1C3 revealed that KS occupied the binding region of AKR1C3 with almost similar orientation as indomethacin (IM), thereby acting as an antagonistic agent for AKR1C3.	Potassium	78-80	aldo-keto reductase family 1 member C3	Homo sapiens	139-145
32209376-8	2020	Molecular docking studies performed to understand the inhibition mechanism of KS on AKR1C3 revealed that KS occupied the binding region of AKR1C3 with almost similar orientation as indomethacin (IM), thereby acting as an antagonistic agent for AKR1C3.	Potassium	105-107	aldo-keto reductase family 1 member C3	Homo sapiens	84-90
32209376-8	2020	Molecular docking studies performed to understand the inhibition mechanism of KS on AKR1C3 revealed that KS occupied the binding region of AKR1C3 with almost similar orientation as indomethacin (IM), thereby acting as an antagonistic agent for AKR1C3.	Potassium	105-107	aldo-keto reductase family 1 member C3	Homo sapiens	139-145
32209376-8	2020	Molecular docking studies performed to understand the inhibition mechanism of KS on AKR1C3 revealed that KS occupied the binding region of AKR1C3 with almost similar orientation as indomethacin (IM), thereby acting as an antagonistic agent for AKR1C3.	Potassium	105-107	aldo-keto reductase family 1 member C3	Homo sapiens	139-145
32209376-9	2020	Based on the results it is identified that KS induces inhibition of AKR1C3 and cell death in MCF-7 cells.	Potassium	43-45	aldo-keto reductase family 1 member C3	Homo sapiens	68-74
32209376-10	2020	These results indicate that KS can be used as a molecular scaffold for further development of novel small-molecules with better specificity towards AKR1C3.	Potassium	28-30	aldo-keto reductase family 1 member C3	Homo sapiens	148-154
32603346-0	2020	Sodium-calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia.	Potassium	59-68	solute carrier family 8 member A1	Homo sapiens	0-26
32572427-4	2020	Serum 5-HT levels were detected with ELISA, and potassium/sodium hyperpolarization activated cyclic nucleotide-gated channel 2 (HCN2) and tryptophan hydroxylase 1 (TPH1) expression levels in colon epithelium of offspring were detected by Western blot and RT-qPCR.	Potassium	48-57	hyperpolarization-activated, cyclic nucleotide-gated K+ 2	Mus musculus	128-132
32572427-4	2020	Serum 5-HT levels were detected with ELISA, and potassium/sodium hyperpolarization activated cyclic nucleotide-gated channel 2 (HCN2) and tryptophan hydroxylase 1 (TPH1) expression levels in colon epithelium of offspring were detected by Western blot and RT-qPCR.	Potassium	48-57	tryptophan hydroxylase 1	Mus musculus	164-168
32937450-1	2020	Kv2.1 channels mediate cell death-enabling loss of cytosolic potassium in neurons following plasma membrane insertion at somatodendritic clusters.	Potassium	61-70	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	0-5
32374168-6	2020	Overall, the observed CBD suppressive effect on NLRP3 inflammasome activation in THP-1 monocytes was associated with decreased potassium efflux, as well as in silico prediction of P2X7 receptor binding.	Potassium	127-136	NLR family pyrin domain containing 3	Homo sapiens	48-53
32374168-6	2020	Overall, the observed CBD suppressive effect on NLRP3 inflammasome activation in THP-1 monocytes was associated with decreased potassium efflux, as well as in silico prediction of P2X7 receptor binding.	Potassium	127-136	GLI family zinc finger 2	Homo sapiens	81-86
32656189-8	2020	Furthermore, ion channel expression was altered in terms of potassium (Kir2.1 overexpression) and calcium handling (dihydropyridine receptor overexpression).	Potassium	60-69	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	71-77
32625100-0	2020	Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2.	Potassium	8-17	angiotensin I converting enzyme	Rattus norvegicus	32-63
32625100-0	2020	Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2.	Potassium	8-17	renin	Rattus norvegicus	65-70
32625100-0	2020	Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2.	Potassium	8-17	angiotensin I converting enzyme 2	Rattus norvegicus	76-107
32625100-4	2020	With the hypothesis that dietary potassium reduces renal vasoconstrictor components of the renin-angiotensin system in the long-term, we studied the effect of high potassium diet on angiotensin-I converting enzyme, renin, and angiotensin converting enzyme 2.	Potassium	33-42	renin	Rattus norvegicus	91-96
32625100-10	2020	Results: High potassium diet (4 weeks) reduced the levels of renin, angiotensin-I converting enzyme, and angiotensin converting enzyme 2.	Potassium	14-23	renin	Rattus norvegicus	61-66
32625100-10	2020	Results: High potassium diet (4 weeks) reduced the levels of renin, angiotensin-I converting enzyme, and angiotensin converting enzyme 2.	Potassium	14-23	angiotensin I converting enzyme	Rattus norvegicus	68-99
32625100-10	2020	Results: High potassium diet (4 weeks) reduced the levels of renin, angiotensin-I converting enzyme, and angiotensin converting enzyme 2.	Potassium	14-23	angiotensin I converting enzyme 2	Rattus norvegicus	105-136
32338831-1	2020	The slow delayed rectifier potassium current (I Ks ) is formed by the KCNQ1 (K v 7.1) channel, an ion channel bearing four alpha-subunits and modulating KCNE1 beta-subunits.	Potassium	27-36	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	70-75
32625100-13	2020	High potassium intake decreased angiotensin converting enzyme 2 gene expression and protein levels (P < 0.01).No morphological abnormalities were observed in renal tissue during high potassium diet.The reduced expression of angiotensin-I converting enzyme, renin, and angiotensin converting enzyme 2 during potassium supplementation suggest that high dietary potassium intake could modulate these vasoactive enzymes and this effects can contribute to the preventive and antihypertensive effect of potassium.	Potassium	5-14	angiotensin I converting enzyme 2	Rattus norvegicus	32-63
32625100-13	2020	High potassium intake decreased angiotensin converting enzyme 2 gene expression and protein levels (P < 0.01).No morphological abnormalities were observed in renal tissue during high potassium diet.The reduced expression of angiotensin-I converting enzyme, renin, and angiotensin converting enzyme 2 during potassium supplementation suggest that high dietary potassium intake could modulate these vasoactive enzymes and this effects can contribute to the preventive and antihypertensive effect of potassium.	Potassium	5-14	angiotensin I converting enzyme	Rattus norvegicus	224-255
32625100-13	2020	High potassium intake decreased angiotensin converting enzyme 2 gene expression and protein levels (P < 0.01).No morphological abnormalities were observed in renal tissue during high potassium diet.The reduced expression of angiotensin-I converting enzyme, renin, and angiotensin converting enzyme 2 during potassium supplementation suggest that high dietary potassium intake could modulate these vasoactive enzymes and this effects can contribute to the preventive and antihypertensive effect of potassium.	Potassium	5-14	renin	Rattus norvegicus	257-262
32338831-1	2020	The slow delayed rectifier potassium current (I Ks ) is formed by the KCNQ1 (K v 7.1) channel, an ion channel bearing four alpha-subunits and modulating KCNE1 beta-subunits.	Potassium	48-50	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	70-75
32552741-12	2020	Blocking potassium efflux or inhibiting caspase-1 prevents 25-HC-potentiated IL-1beta release in apoE4-expressing microglia, indicating the involvement of caspase-1 inflammasome activity.	Potassium	9-18	interleukin 1 alpha	Mus musculus	77-85
32514747-4	2020	Subsequent analysis suggested that SAPK2 considerably influences the nitrogen, phosphorus, and potassium contents of rice grains.	Potassium	95-104	serine/threonine-protein kinase SAPK2	Oryza sativa Japonica Group	35-40
32359429-4	2020	Analysis of the naked mole-rat genome revealed, uniquely among mammals, a histidine point variation in the neuronal potassium-chloride cotransporter 2 (KCC2).	Potassium	116-125	solute carrier family 12 member 5	Homo sapiens	152-156
32488011-2	2020	We now show that FMRP is a member of a Cav3-Kv4 ion channel complex that is known to regulate A-type potassium current in cerebellar granule cells to produce mossy fiber LTP.	Potassium	101-110	fragile X messenger ribonucleoprotein 1	Mus musculus	17-21
32490811-2	2020	We found two firing phenotypes of CCK+INs in rat hippocampal CA3 area; either possessing a previously undetected membrane potential-dependent firing or regular firing phenotype, due to different low-voltage-activated potassium currents.	Potassium	217-226	cholecystokinin	Rattus norvegicus	34-37
32582195-6	2020	A mechanistic study revealed that S. sonnei induced IL-1beta production through P2X7 receptor-mediated potassium efflux, reactive oxygen species generation, lysosomal acidification, and mitochondrial damage.	Potassium	103-112	interleukin 1 alpha	Homo sapiens	52-60
32488011-2	2020	We now show that FMRP is a member of a Cav3-Kv4 ion channel complex that is known to regulate A-type potassium current in cerebellar granule cells to produce mossy fiber LTP.	Potassium	101-110	caveolin 3	Mus musculus	39-43
32488011-2	2020	We now show that FMRP is a member of a Cav3-Kv4 ion channel complex that is known to regulate A-type potassium current in cerebellar granule cells to produce mossy fiber LTP.	Potassium	101-110	potassium voltage gated channel, Shaw-related subfamily, member 1	Mus musculus	44-47
32008360-1	2020	The potassium voltage-gated channel subfamily J member 11 gene (KCNJ11) is involved in the insulin secretion pathway.	Potassium	4-13	potassium inwardly rectifying channel subfamily J member 11	Gallus gallus	64-70
32338037-7	2020	In addition, male KS-BMAL1 KO had less sodium retention compared to CNTL in response to a potassium-restricted diet (15% less following 5 days of treatment).	Potassium	90-99	aryl hydrocarbon receptor nuclear translocator-like	Mus musculus	21-26
32299681-0	2020	Collecting system-specific deletion of Kcnj10 predisposes for thiazide- and low-potassium diet-induced hypokalemia.	Potassium	80-89	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	39-45
31935579-3	2020	Aim of this work is to assess the effect of four drugs blocking the human ether-a-go-go-related gene (hERG) potassium channel, alone or in combination with other ionic channel blocks, on SHVR, as estimated by the V-index on short triplicate 10 s ECG.	Potassium	108-117	ETS transcription factor ERG	Homo sapiens	102-106
32155353-5	2020	Aquaporin-4 (AQP4) is implicated in a number of physiopathological processes, particularly in the development of brain edema, and other functions such as the regulation of extracellular space volume, potassium buffering, waste clearance, and calcium signaling.	Potassium	200-209	aquaporin 4	Bos taurus	13-17
31792968-0	2020	Down-regulation of miR-3068-3p enhances kcnip4-regulated A-type potassium current to protect against glutamate-induced excitotoxicity.	Potassium	64-73	potassium voltage-gated channel interacting protein 4	Rattus norvegicus	40-46
31792968-7	2020	Additional luciferase assays and western blots validated kcnip4, a Kv4-mediated A-type potassium current (IA ) regulator, as a direct target of miR-3068-3p.	Potassium	87-96	potassium voltage-gated channel interacting protein 4	Rattus norvegicus	57-63
32352602-8	2020	As shown by immunostaining of endothelial makers, renal vascular densities were decreased accompanied by increased HIF-1alpha and erythropoietin levels in the kidneys of KS-tg/OVE mice.	Potassium	170-172	hypoxia inducible factor 1, alpha subunit	Mus musculus	115-125
32352602-8	2020	As shown by immunostaining of endothelial makers, renal vascular densities were decreased accompanied by increased HIF-1alpha and erythropoietin levels in the kidneys of KS-tg/OVE mice.	Potassium	170-172	erythropoietin	Mus musculus	130-144
32295826-7	2020	Double-knockout mice lacking both Kir4.1/Kir5.1 and Nedd4-2 in the kidney exhibited increased expression of the epithelial sodium channel alpha-subunit, largely abolished basolateral potassium ion conductance (to a degree similar to that of kidney-specific Kir4.1 knockout mice), and depolarization of the DCT membrane.	Potassium	183-192	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	34-40
32295826-7	2020	Double-knockout mice lacking both Kir4.1/Kir5.1 and Nedd4-2 in the kidney exhibited increased expression of the epithelial sodium channel alpha-subunit, largely abolished basolateral potassium ion conductance (to a degree similar to that of kidney-specific Kir4.1 knockout mice), and depolarization of the DCT membrane.	Potassium	183-192	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	41-47
32295826-7	2020	Double-knockout mice lacking both Kir4.1/Kir5.1 and Nedd4-2 in the kidney exhibited increased expression of the epithelial sodium channel alpha-subunit, largely abolished basolateral potassium ion conductance (to a degree similar to that of kidney-specific Kir4.1 knockout mice), and depolarization of the DCT membrane.	Potassium	183-192	neural precursor cell expressed, developmentally down-regulated gene 4-like	Mus musculus	52-59
30189765-9	2020	CONCLUSIONS: Conventional dose insulin may be more effective than reduced dose regular insulin at baseline serum potassium levels &gt;6 mmol/L in the treatment of hyperkalemia.	Potassium	113-122	insulin	Homo sapiens	31-38
30189765-9	2020	CONCLUSIONS: Conventional dose insulin may be more effective than reduced dose regular insulin at baseline serum potassium levels &gt;6 mmol/L in the treatment of hyperkalemia.	Potassium	113-122	insulin	Homo sapiens	87-94
30189765-10	2020	Frequent monitoring of serum potassium and glucose after administration of insulin is necessary to confirm adequate response and avoidance of hypoglycemia.	Potassium	29-38	insulin	Homo sapiens	75-82
32525548-18	2020	Conclusions and Relevance: The correction of hypokalemia is challenging because of continuous renal potassium loss resulting from the degradation of angiotensin-converting enzyme 2.	Potassium	100-109	angiotensin converting enzyme 2	Homo sapiens	149-180
32299681-6	2020	Collecting system-Kcnj10-knockout mice responded normally to standard and high potassium diet.	Potassium	79-88	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	18-24
32299681-11	2020	Thus, KCNJ10 in the collecting system contributes to the renal control of potassium homeostasis by regulating ENaC and ROMK.	Potassium	74-83	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	6-12
32299681-11	2020	Thus, KCNJ10 in the collecting system contributes to the renal control of potassium homeostasis by regulating ENaC and ROMK.	Potassium	74-83	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	110-114
32299681-11	2020	Thus, KCNJ10 in the collecting system contributes to the renal control of potassium homeostasis by regulating ENaC and ROMK.	Potassium	74-83	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	119-123
32299681-12	2020	Hence, impaired KCNJ10 function in the collecting system predisposes for thiazide and low potassium diet-induced hypokalemia and likely contributes to the pathophysiology of renal potassium loss in EAST/SeSAME syndrome.	Potassium	90-99	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	16-22
32299681-12	2020	Hence, impaired KCNJ10 function in the collecting system predisposes for thiazide and low potassium diet-induced hypokalemia and likely contributes to the pathophysiology of renal potassium loss in EAST/SeSAME syndrome.	Potassium	180-189	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	16-22
32167513-4	2020	The FeCo@C@MoS2 electrode displays high reversible capacities of 380 mA h g-1 and 147 mA h g-1 at 500 mA g-1 for sodium and potassium storage, respectively.	Potassium	124-133	proline rich protein BstNI subfamily 3	Homo sapiens	74-108
32508821-7	2020	NLRP3 inflammasome assembly is triggered by extracellular ATP, reactive oxygen species (ROS), potassium efflux, calcium misbalance, and lysosome disruption.	Potassium	94-103	NLR family pyrin domain containing 3	Homo sapiens	0-5
32374315-4	2020	The obtained VN/CNF composite anode exhibited excellent half/full sodium and potassium storage performance.	Potassium	77-86	NPHS1 adhesion molecule, nephrin	Homo sapiens	16-19
32509580-6	2020	The blockade of epidermal growth factor receptor (EGFR) by anti-EGFR antibodies can result in clinically significant magnesium and potassium losses.	Potassium	131-140	epidermal growth factor receptor	Homo sapiens	16-48
32499707-1	2020	Inwardly rectifying potassium (KIR) channels play important roles in controlling cellular excitability and K+ ion homeostasis.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
32499717-8	2020	TREK-1 and Piezo1 have been selected, as they are widely expressed in the body, including cardiac tissue, and they are "canonical representatives" for the potassium selective and the cation non-selective SAC families, respectively.	Potassium	155-164	potassium two pore domain channel subfamily K member 2	Homo sapiens	0-6
32499717-8	2020	TREK-1 and Piezo1 have been selected, as they are widely expressed in the body, including cardiac tissue, and they are "canonical representatives" for the potassium selective and the cation non-selective SAC families, respectively.	Potassium	155-164	piezo type mechanosensitive ion channel component 1	Homo sapiens	11-17
32088442-3	2020	Result indicated that potassium was successfully doped into the g-C3N4 framework via direct heating the mixture of melamine and potassium iodide at 520  C, which increases the BET surface area, broadens the visible light response region, and elevates the separation efficiency of electron-hole pairs.	Potassium	22-31	delta/notch like EGF repeat containing	Homo sapiens	176-179
32286583-0	2020	A mitochondria-targeting NIR fluorescent potassium ion sensor: real-time investigation of the mitochondrial K+ regulation of apoptosis in situ.	Potassium	41-50	NOC2 like nucleolar associated transcriptional repressor	Homo sapiens	25-28
32509580-6	2020	The blockade of epidermal growth factor receptor (EGFR) by anti-EGFR antibodies can result in clinically significant magnesium and potassium losses.	Potassium	131-140	epidermal growth factor receptor	Homo sapiens	50-54
32392309-2	2020	Retinoschisin specifically interacts with the retinal sodium-potassium adenosine triphosphatase (Na/K-ATPase), a transmembrane ion pump.	Potassium	61-70	retinoschisis (X-linked, juvenile) 1 (human)	Mus musculus	0-13
32509580-6	2020	The blockade of epidermal growth factor receptor (EGFR) by anti-EGFR antibodies can result in clinically significant magnesium and potassium losses.	Potassium	131-140	epidermal growth factor receptor	Homo sapiens	64-68
32053194-0	2020	The calcineurin beta-like interacting protein kinase CIPK25 regulates potassium homeostasis under low oxygen in Arabidopsis.	Potassium	70-79	CBL-interacting protein kinase 25	Arabidopsis thaliana	53-59
32053194-3	2020	A cipk25 mutant exhibited higher sensitivity to anoxia in conditions of potassium limitation, suggesting that this kinase is involved in the regulation of potassium uptake.	Potassium	72-81	CBL-interacting protein kinase 25	Arabidopsis thaliana	2-8
32053194-3	2020	A cipk25 mutant exhibited higher sensitivity to anoxia in conditions of potassium limitation, suggesting that this kinase is involved in the regulation of potassium uptake.	Potassium	155-164	CBL-interacting protein kinase 25	Arabidopsis thaliana	2-8
32053194-4	2020	Interestingly, we found that CIPK25 interacts with AKT1, the major inward rectifying potassium channel in Arabidopsis.	Potassium	85-94	CBL-interacting protein kinase 25	Arabidopsis thaliana	29-35
32053194-4	2020	Interestingly, we found that CIPK25 interacts with AKT1, the major inward rectifying potassium channel in Arabidopsis.	Potassium	85-94	K+ transporter 1	Arabidopsis thaliana	51-55
32053194-5	2020	Under anoxic conditions, cipk25 mutant seedlings were unable to maintain potassium concentrations at wild-type levels, suggesting that CIPK25 likely plays a role in modulating potassium homeostasis under low-oxygen conditions.	Potassium	176-185	CBL-interacting protein kinase 25	Arabidopsis thaliana	25-31
32053194-5	2020	Under anoxic conditions, cipk25 mutant seedlings were unable to maintain potassium concentrations at wild-type levels, suggesting that CIPK25 likely plays a role in modulating potassium homeostasis under low-oxygen conditions.	Potassium	176-185	CBL-interacting protein kinase 25	Arabidopsis thaliana	135-141
32398094-3	2020	p13 is mainly localized in the inner membrane of the mitochondria, where it induces potassium (K+) influx and reactive oxygen species (ROS) production, which can trigger either proliferation or apoptosis, depending on the ROS setpoint of the cell.	Potassium	84-93	H3 histone pseudogene 6	Homo sapiens	0-3
31754927-0	2020	The potassium channel Kcne3 is a VEGFA-inducible gene selectively expressed by vascular endothelial tip cells.	Potassium	4-13	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	22-27
32376987-3	2020	Herein, we found that a guanine rich tract, capable of forming intramolecular G-quadruplex in the presence of potassium ions, in the promoter region of human TMPRSS2 gene was quite important for gene transcriptional activity, hence affecting its function.	Potassium	110-119	transmembrane serine protease 2	Homo sapiens	158-165
31754927-0	2020	The potassium channel Kcne3 is a VEGFA-inducible gene selectively expressed by vascular endothelial tip cells.	Potassium	4-13	vascular endothelial growth factor A	Homo sapiens	33-38
31900739-0	2020	Dietary potassium restriction attenuates urinary sodium wasting in the generalized form of pseudohypoaldosteronism type 1.	Potassium	8-17	sodium channel epithelial 1 subunit gamma	Homo sapiens	91-121
32004973-7	2020	The activation of the P2X7R can open the ion channels on the tumor cell membrane (sodium ion, calcium ion influx and potassium ion outflow), trigger rearrangement of the cytoskeleton and changes in membrane fluidity, allow small molecule substances to enter the cell, activate enzymes and kinases in related signaling pathways in cells (such as PKA, PKC, ERK1/2, AKT, and JNK), thereby affecting the development of tumor cells, and can also indirectly affect the growth, apoptosis and migration of tumor cells through tumor microenvironment.	Potassium	117-126	purinergic receptor P2X 7	Homo sapiens	22-27
31825788-0	2020	The membrane protein KCNQ1 potassium ion channel: Functional diversity and current structural insights.	Potassium	27-36	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	21-26
31900739-8	2020	Thus, potassium restriction causes NCC and pendrin to compensate for the non-functional ENaC in the collecting duct.	Potassium	6-15	solute carrier family 26 member 4	Homo sapiens	43-50
31900739-2	2020	In particular, the usefulness of dietary potassium restriction in PHA1 remains unclear with the absence of theoretical background to elucidate its utility.	Potassium	41-50	sodium channel epithelial 1 subunit gamma	Homo sapiens	66-70
31900739-9	2020	In conclusion, dietary potassium restriction is one of the indispensable treatments for generalized PHA1.	Potassium	23-32	sodium channel epithelial 1 subunit gamma	Homo sapiens	100-104
31900739-3	2020	First, we demonstrated the effect of potassium restriction in a 13-month-old patient with ENaC gamma-subunit gene mutations via a retrospective chart review; reduction of daily dietary potassium intake from 40 to 20 mEq induced rapid restoration of volume depletion, as evidenced by weight gain, elevation of the serum sodium level from 133 to 141 mEq/L, decreased urinary sodium excretion, and normalized renin activity.	Potassium	37-46	sodium channel epithelial 1 subunit gamma	Homo sapiens	90-108
31881264-1	2020	As one important member of the two-pore-domain potassium channel (K2P) family, potassium channel subfamily K member 3 (KCNK3) has been reported for thermogenesis regulation, energy homeostasis, membrane potential conduction, and pulmonary hypertension in mammals.	Potassium	47-56	potassium channel subfamily K member 3	Oreochromis niloticus	119-124
31781992-9	2020	Additionally, it was found that BnFAD3 is a transmembrane protein that can convert omega6 to omega3 fatty acids and may simultaneously act as a potassium ion channel in the ER.	Potassium	144-153	omega-3 fatty acid desaturase, endoplasmic reticulum	Brassica napus	32-38
31881264-1	2020	As one important member of the two-pore-domain potassium channel (K2P) family, potassium channel subfamily K member 3 (KCNK3) has been reported for thermogenesis regulation, energy homeostasis, membrane potential conduction, and pulmonary hypertension in mammals.	Potassium	79-88	potassium channel subfamily K member 3	Oreochromis niloticus	119-124
32027066-2	2020	These genes encode the subunits of the beta-cell ATP sensitive potassium channel, a key component of the glucose-stimulated insulin secretion pathway.	Potassium	63-72	insulin	Homo sapiens	124-131
32037944-8	2020	For tactile stimulus, the following active ingredients showed large beneficial effects compared to fluoride with moderate certainty of evidence (SMD; 95% CI): potassium + stannous fluoride (SnF2) (3.05; 1.69-4.41), calcium sodium phosphosilicate (CSP) (2.14; 0.75-3.53), SnF2 (2.02; 1.06-2.99), potassium + hydroxyapatite (2.47; 0.3-4.64), strontium (1.43; 0.46-2.41), and potassium (1.23; 0.48-1.98).	Potassium	159-168	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	190-194
31856407-0	2020	Formate and potassium ions affect Escherichia coli proton ATPase activity at low pH during mixed carbon fermentation.	Potassium	12-21	ATPase	Escherichia coli	58-64
31856407-8	2020	Taken together, the data suggest that proton ATPase activity depends on externally added formate in the presence of potassium ions at low pH.	Potassium	116-125	ATPase	Escherichia coli	45-51
31901677-0	2020	Elucidation of interaction mechanism of hERG1 potassium channel with scorpion toxins BeKm-1 and BmTx3b.	Potassium	46-55	potassium voltage-gated channel subfamily H member 2	Homo sapiens	40-45
31420581-10	2020	Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females.	Potassium	10-19	S100 calcium binding protein A10	Homo sapiens	62-65
31420581-10	2020	Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females.	Potassium	10-19	coilin	Homo sapiens	71-74
31420581-10	2020	Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females.	Potassium	10-19	coiled-coil domain containing 8	Homo sapiens	89-92
31420581-10	2020	Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females.	Potassium	10-19	S100 calcium binding protein A10	Homo sapiens	143-146
31420581-10	2020	Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females.	Potassium	10-19	coiled-coil domain containing 8	Homo sapiens	152-155
32067254-3	2020	As activity-induced potassium transients are rapidly managed by astrocytic Kir4.1 and astrocyte-specific Na+ /K+ -ATPase, any neurotransmitter/neuromodulator that can regulate their function may have indirect influence on network activity.	Potassium	20-29	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	75-81
31420581-9	2020	Intake of potassium was, however, negatively associated with SBP (P20-P30, P70-P80) in males, and also negatively associated with SBP (P10-P80) and DBP(P20-P50) in females.	Potassium	10-19	coilin	Homo sapiens	79-82
31420581-9	2020	Intake of potassium was, however, negatively associated with SBP (P20-P30, P70-P80) in males, and also negatively associated with SBP (P10-P80) and DBP(P20-P50) in females.	Potassium	10-19	S100 calcium binding protein A10	Homo sapiens	135-138
31420581-9	2020	Intake of potassium was, however, negatively associated with SBP (P20-P30, P70-P80) in males, and also negatively associated with SBP (P10-P80) and DBP(P20-P50) in females.	Potassium	10-19	coilin	Homo sapiens	139-142
32492001-9	2020	In conclusion, our results suggest that the ZmHAK1 regulation has an important role in the process of absorbing potassium ions, and possibly in the response of maize to abiotic stress.	Potassium	112-121	Potassium transporter 1	Zea mays	44-50
32543130-4	2020	Results: The area under the ROC curve ( AUC) of the plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio (ARR) was greater than that of the ratio of the upright PAC to the angiotensin II (AT-II) (AA2R), upright PRA, upright PAC, supine ARR, and lowest blood potassium ( P<0.05).	Potassium	281-290	renin	Homo sapiens	101-106
32327288-1	2020	Nav1.4 channelopathies due to SCN4A mutations can present with episodic attacks of myotonia triggered by fluctuation in the potassium level (potassium-aggravated myotonia).	Potassium	124-133	sodium voltage-gated channel alpha subunit 4	Homo sapiens	0-6
32327288-1	2020	Nav1.4 channelopathies due to SCN4A mutations can present with episodic attacks of myotonia triggered by fluctuation in the potassium level (potassium-aggravated myotonia).	Potassium	124-133	sodium voltage-gated channel alpha subunit 4	Homo sapiens	30-35
32327288-1	2020	Nav1.4 channelopathies due to SCN4A mutations can present with episodic attacks of myotonia triggered by fluctuation in the potassium level (potassium-aggravated myotonia).	Potassium	141-150	sodium voltage-gated channel alpha subunit 4	Homo sapiens	0-6
32327288-1	2020	Nav1.4 channelopathies due to SCN4A mutations can present with episodic attacks of myotonia triggered by fluctuation in the potassium level (potassium-aggravated myotonia).	Potassium	141-150	sodium voltage-gated channel alpha subunit 4	Homo sapiens	30-35
32327288-2	2020	We report a case of potassium-aggravated myotonia due to Nav1.4-M1592V channelopathy with severe and long-lasting focal attacks of myotonia resembling dystonic posturing with diffuse muscle edema in the affected muscles in magnetic resonance imaging and almost constant presence of myotonic discharges in electromyography that can best be described as focal "status myotonicus".	Potassium	20-29	sodium voltage-gated channel alpha subunit 4	Homo sapiens	57-63
32408404-0	2020	Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2.	Potassium	48-57	microRNA 137	Mus musculus	8-20
32297137-7	2020	To elucidate the role of potassium efflux as an upstream signal of NLRP3 inflammasome activation, equine PBMCs were treated with blockers of potassium efflux in the presence of NLRP3 triggers.	Potassium	25-34	NLR family pyrin domain containing 3	Equus caballus	67-72
32408404-0	2020	Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2.	Potassium	48-57	solute carrier family 12, member 5	Mus musculus	73-77
32408404-4	2020	Here we generated a forebrain-specific MIR137 knockout mouse model, and provided evidence that loss of miR-137 resulted in impaired homeostasis of potassium in mouse hippocampal neurons.	Potassium	147-156	microRNA 137	Mus musculus	103-110
32408404-6	2020	The KCC2 specific antagonist VU0240551 could balance the current of potassium in miR-137 knockout neurons, and knockdown of KCC2 could ameliorate anxiety-like behavior in MIR137 cKO mice.	Potassium	68-77	solute carrier family 12, member 5	Mus musculus	4-8
32408404-6	2020	The KCC2 specific antagonist VU0240551 could balance the current of potassium in miR-137 knockout neurons, and knockdown of KCC2 could ameliorate anxiety-like behavior in MIR137 cKO mice.	Potassium	68-77	microRNA 137	Mus musculus	81-88
31991212-5	2020	At physiological pH, the degree of elastin mineralization is influenced by hydrolysis and complexity of medium composition, since ionic species, as sodium, potassium, magnesium, in addition to calcium and phosphorus, interfere with the calcification process.	Potassium	156-165	elastin	Homo sapiens	35-42
32426734-9	2020	Conclusions: Patients treated for hyperkalemia with insulin doses less than 10 units had reduced frequency of hypoglycemia; however, potassium reduction post treatment was more modest in these patients.	Potassium	133-142	insulin	Homo sapiens	52-59
32233369-0	2020	Combined Experimental and Theoretical Studies on Electron-Transfer in Potassium Collisions with CCl4.	Potassium	70-79	C-C motif chemokine ligand 4	Homo sapiens	96-100
32233369-2	2020	Comprehensive calculations on the electronic structure were performed for CCl4 in the presence of a potassium atom and used to help analyse the lowest unoccupied molecular orbitals participating in the collision process.	Potassium	100-109	C-C motif chemokine ligand 4	Homo sapiens	74-78
32193365-3	2020	Mitral and tufted (M/T) neurons from Mitf mutant mice are hyperexcitable, have a reduced Type-A potassium current (IA) and exhibit reduced expression of Kcnd3, which encodes a potassium voltage-gated channel subunit (Kv4.3) important for generating the IA Furthermore, expression of the Mitf and Kcnd3 genes is activity-dependent in OB projection neurons and the MITF protein activates expression from Kcnd3 regulatory elements.	Potassium	96-105	melanogenesis associated transcription factor	Mus musculus	37-41
32351384-2	2020	Like for all potassium channels, opening of EAG channels drives the membrane potential toward its equilibrium value for potassium, thus setting the resting potential and repolarizing action potentials.	Potassium	13-22	potassium voltage-gated channel subfamily H member 1	Homo sapiens	44-47
31722434-1	2020	STUDY OBJECTIVES: Recently, a role for gain-of-function (GoF) mutations of the astrocytic potassium channel Kir4.1 (KCNJ10 gene) has been proposed in subjects with Autism-Epilepsy phenotype (AEP).	Potassium	90-99	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	108-114
31722434-1	2020	STUDY OBJECTIVES: Recently, a role for gain-of-function (GoF) mutations of the astrocytic potassium channel Kir4.1 (KCNJ10 gene) has been proposed in subjects with Autism-Epilepsy phenotype (AEP).	Potassium	90-99	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	116-122
31967857-9	2020	Hypoxia induced changes in CB Type I cell redox ratio affected peptidyl prolyl isomerase Pin1, which is believed to co-localize with the NADPH oxidase subunit p47phox in the cell membrane to trigger the opening of potassium channels.	Potassium	214-223	neutrophil cytosolic factor 1	Mus musculus	159-166
32292023-5	2020	Genetic analysis demonstrated a novel heterozygous mutation in the SLC12A3 gene; therefore, we diagnosed GS and started potassium and magnesium replacement.	Potassium	120-129	solute carrier family 12 member 3	Homo sapiens	67-74
32168096-3	2020	Astrocytes grown in hyperglycemic conditions have decreased levels of Kir4.1 potassium channels as well as impaired potassium and glutamate uptake.	Potassium	77-86	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	70-76
31999038-3	2020	Both the NiO5 single-atom active centers and nanotube framework endow the Ni/S/C ternary composite with accelerated reaction kinetics for potassium-ion storage.	Potassium	138-147	solute carrier family 5 member 5	Homo sapiens	74-78
32318578-11	2020	Conclusion: The baseline anti-EPO antibody level combined with an older age and a higher predialysis potassium ion concentration are independent predictors for a higher follow-up EPO demand in maintenance dialysis patients with ESRD.	Potassium	101-110	erythropoietin	Homo sapiens	30-33
32318578-11	2020	Conclusion: The baseline anti-EPO antibody level combined with an older age and a higher predialysis potassium ion concentration are independent predictors for a higher follow-up EPO demand in maintenance dialysis patients with ESRD.	Potassium	101-110	erythropoietin	Homo sapiens	179-182
32255892-7	2020	Although maize yield response to fertilizer differed with geographic location; on average, maize yield response to nitrogen (N), phosphorus (P) and potassium (K) were respectively 2.4, 1.6 and 0.2 t ha-1 in Nigeria, 2.3, 0.9 and 0.2 t ha-1 in Ethiopia, and 1.5, 0.8 and 0.2 t ha-1 in Tanzania.	Potassium	148-157	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	199-203
31967857-10	2020	We postulate that hypoxia-induced changes in the Fp mediated redox ratio of the CB regulate the Pin1/p47phox tandem to alter Type I cell potassium channels and therewith CND.	Potassium	137-146	peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1	Mus musculus	96-100
31967857-10	2020	We postulate that hypoxia-induced changes in the Fp mediated redox ratio of the CB regulate the Pin1/p47phox tandem to alter Type I cell potassium channels and therewith CND.	Potassium	137-146	neutrophil cytosolic factor 1	Mus musculus	101-108
31984792-4	2020	We previously showed that the basolateral membrane of principal cells has primarily potassium conductance mediated by Kir4.1/5.1 channels to mediate K+ recycling and to set up a favorable driving force for Na+/K+ exchange.	Potassium	84-93	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	118-124
31962128-11	2020	Mechanistically, we showed that potassium-induced cortical spreading depression episodes were inhibited, including frequency and duration of DC shift, in CNO-treated hM4Di-TG mice.	Potassium	32-41	biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino	Mus musculus	154-157
32255279-10	2020	When the short-term stability of the serum potassium was observed for 30, 12, and 4 days at 2 - 8 C, room temperature, and 37 C, respectively,  b1  < t0.95, n - 2 sb1, and instability was not observed.	Potassium	43-52	SH3KBP1 binding protein 1	Homo sapiens	163-166
32015077-0	2020	Recognition and activation of the plant AKT1 potassium channel by the kinase CIPK23.	Potassium	45-54	K+ transporter 1	Arabidopsis thaliana	40-44
32160100-4	2020	Here, we show that LSD1 genotype (in humans) and LSD1 deficiency (in mice) lead to similar associations with increased blood pressure and urine potassium levels but with decreased aldosterone levels during a liberal salt diet.	Potassium	144-153	lysine demethylase 1A	Homo sapiens	19-23
32160100-4	2020	Here, we show that LSD1 genotype (in humans) and LSD1 deficiency (in mice) lead to similar associations with increased blood pressure and urine potassium levels but with decreased aldosterone levels during a liberal salt diet.	Potassium	144-153	lysine demethylase 1A	Homo sapiens	49-53
32034107-8	2020	In aldosterone-treated NCC knockout mice showing upregulation of pendrin, potassium supplementation corrected alkalosis and inhibited the pendrin upregulation, thereby lowering BP.	Potassium	74-83	solute carrier family 26, member 4	Mus musculus	65-72
32034107-8	2020	In aldosterone-treated NCC knockout mice showing upregulation of pendrin, potassium supplementation corrected alkalosis and inhibited the pendrin upregulation, thereby lowering BP.	Potassium	74-83	solute carrier family 26, member 4	Mus musculus	138-145
31692055-3	2020	In this study, we identified two lysine sites, K21 and K123, that were critical ubiquitin-binding sites in BAX.	Potassium	55-59	BCL2 associated X, apoptosis regulator	Homo sapiens	107-110
32128683-2	2020	Studies in porcine kidney BADH (pkBADH) suggested that the enzyme exhibits heterogeneity of active sites and undergoes potassium-induced conformational changes.	Potassium	119-128	aldehyde dehydrogenase 7 family member A1	Homo sapiens	26-30
31439721-5	2020	For functional characterisation of the identified variants, potassium influx of mutated KCC3 cotransporters was measured in Xenopus oocytes.	Potassium	60-69	solute carrier family 12 member 6 L homeolog	Xenopus laevis	88-92
31439721-9	2020	Modelling of the mutant KCC3 cotransporter in Xenopus oocytes showed a significant reduction in potassium influx for both changes.	Potassium	96-105	solute carrier family 12 member 6 L homeolog	Xenopus laevis	24-28
32111696-3	2020	Previous work established that cocaine/methamphetamine exposure increases protein phosphatase 2A (PP2A) activity, which dephosphorylates the GABABR2 subunit, promotes internalization of the GABAB receptor (GABABR) and leads to smaller GABABR-activated G-protein-gated inwardly rectifying potassium (GIRK) currents in VTA GABA neurons.	Potassium	288-297	protein phosphatase 2, regulatory subunit A, alpha	Mus musculus	98-102
32111696-3	2020	Previous work established that cocaine/methamphetamine exposure increases protein phosphatase 2A (PP2A) activity, which dephosphorylates the GABABR2 subunit, promotes internalization of the GABAB receptor (GABABR) and leads to smaller GABABR-activated G-protein-gated inwardly rectifying potassium (GIRK) currents in VTA GABA neurons.	Potassium	288-297	gamma-aminobutyric acid type B receptor subunit 2	Rattus norvegicus	141-148
32015077-0	2020	Recognition and activation of the plant AKT1 potassium channel by the kinase CIPK23.	Potassium	45-54	CBL-interacting protein kinase 23	Arabidopsis thaliana	77-83
32179729-1	2020	BACKGROUND Insulin lowers not only blood glucose levels but also serum potassium levels by driving potassium into the cells.	Potassium	71-80	insulin	Homo sapiens	11-18
31954182-1	2020	Upon transition from research to development, a new chemical entity, which acts upon the Kv1.5-potassium channel and blocks potassium flow in the atrium of the human heart, has been subjected to a crystallization screen.	Potassium	95-104	potassium voltage-gated channel subfamily A member 5	Homo sapiens	89-94
31954182-1	2020	Upon transition from research to development, a new chemical entity, which acts upon the Kv1.5-potassium channel and blocks potassium flow in the atrium of the human heart, has been subjected to a crystallization screen.	Potassium	124-133	potassium voltage-gated channel subfamily A member 5	Homo sapiens	89-94
32235870-1	2020	Potassium depletion affects AQP2 expression and the cellular composition of the kidney collecting duct.	Potassium	0-9	aquaporin 2	Rattus norvegicus	28-32
33997174-1	2021	Inwardly rectifying potassium (Kir) channels make it easier for K+ to enter into a cell and subsequently regulate cellular biological functions.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
32270035-1	2020	The potassium channel Kv7.1 associates with the KCNE1 regulatory subunit to trigger cardiac I Ks currents.	Potassium	94-96	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	22-27
32270035-1	2020	The potassium channel Kv7.1 associates with the KCNE1 regulatory subunit to trigger cardiac I Ks currents.	Potassium	94-96	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	48-53
32270035-4	2020	Kv7.1 and KCNE1 mutations, responsible for long QT syndromes, impair association and traffic, thereby altering I Ks currents.	Potassium	113-115	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-5
32270035-4	2020	Kv7.1 and KCNE1 mutations, responsible for long QT syndromes, impair association and traffic, thereby altering I Ks currents.	Potassium	113-115	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	10-15
32328491-3	2020	However, pathways triggering NLRP3 activation, such as potassium efflux, ROS production or lysosomal permeabilization, can be required or not, depending on the activators used.	Potassium	55-64	NLR family pyrin domain containing 3	Homo sapiens	29-34
32179729-1	2020	BACKGROUND Insulin lowers not only blood glucose levels but also serum potassium levels by driving potassium into the cells.	Potassium	99-108	insulin	Homo sapiens	11-18
32161292-6	2020	A molecular docking model was proposed in which Arg79 of the SVSP 99-loop interacts directly with the potassium selectivity filter of the hEAG1 channel.	Potassium	102-111	potassium voltage-gated channel subfamily H member 1	Homo sapiens	138-143
31846835-0	2020	Potassium-dependent sodium-calcium exchanger (NCKX) isoforms and neuronal function.	Potassium	0-9	solute carrier family 24 member 1	Homo sapiens	46-50
31984791-2	2020	NHERF1 is involved in the regulation of the sodium hydrogen exchanger 3 (NHE3), the sodium dependent phosphate transporter 2a (Npt2a), and the sodium potassium ATPase through its ability to scaffold these transporters to the plasma membrane, allowing regulation of these protein complexes with their associated hormone receptors.	Potassium	143-159	SLC9A3 regulator 1	Homo sapiens	0-6
31984791-2	2020	NHERF1 is involved in the regulation of the sodium hydrogen exchanger 3 (NHE3), the sodium dependent phosphate transporter 2a (Npt2a), and the sodium potassium ATPase through its ability to scaffold these transporters to the plasma membrane, allowing regulation of these protein complexes with their associated hormone receptors.	Potassium	143-159	solute carrier family 9 member A3	Homo sapiens	44-71
31984791-2	2020	NHERF1 is involved in the regulation of the sodium hydrogen exchanger 3 (NHE3), the sodium dependent phosphate transporter 2a (Npt2a), and the sodium potassium ATPase through its ability to scaffold these transporters to the plasma membrane, allowing regulation of these protein complexes with their associated hormone receptors.	Potassium	143-159	dynein axonemal heavy chain 8	Homo sapiens	160-166
31835175-3	2020	We therefore tested the effect of genetic inactivation of K-Cl cotransporters KCC1 and KCC3 in a mouse model of beta-thalassemia intermedia.	Potassium	58-62	solute carrier family 12, member 4	Mus musculus	78-82
31835175-3	2020	We therefore tested the effect of genetic inactivation of K-Cl cotransporters KCC1 and KCC3 in a mouse model of beta-thalassemia intermedia.	Potassium	58-62	solute carrier family 12, member 6	Mus musculus	87-91
31866408-6	2020	The effect of HSYA on the large conductance Ca2+ activated and voltage-gated potassium channel (BKCa channel) currents in rat mesentery artery and on L-type calcium channel (Ca-L) currents in HEK293cells expressed with Ca-L were investigated using patch clamp techniques.	Potassium	77-86	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	96-100
31916164-15	2020	The first component (PC1) showed high loadings on B-SOD, L-SOD, B-MDA, L-MDA, K-MDA, iNOS, tNOS, and AChE and accounted for 46.55% of the total variance after Varimax rotation.	Potassium	78-83	minisatellite 6 hypermutable	Mus musculus	21-24
31782179-1	2020	TREK-1 (TWIK-related K+ channel), a member of the two-pore domain K+ (K2P) channel family, is highly expressed in astrocytes, where it plays a key role in glutamate release and passive conductance.	Potassium	70-73	potassium two pore domain channel subfamily K member 2	Homo sapiens	0-6
31926846-1	2020	Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) is a rare, developmental and epileptic encephalopathy most commonly associated with mutations in KCNT1, a potassium channel.	Potassium	164-173	potassium sodium-activated channel subfamily T member 1	Homo sapiens	155-160
31868992-4	2020	One of the main challenges of hiPSC-CMs is the physiologic expression of ion channels such as the inward rectifiers (e.g., Kir2.1-2.3), which conduct the cardiac inward rectifier potassium current (IK1 ).	Potassium	179-188	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	123-129
31868992-4	2020	One of the main challenges of hiPSC-CMs is the physiologic expression of ion channels such as the inward rectifiers (e.g., Kir2.1-2.3), which conduct the cardiac inward rectifier potassium current (IK1 ).	Potassium	179-188	IKAROS family zinc finger 1	Homo sapiens	198-201
31916164-16	2020	PC2 accounted for 23.81% of the total variance with high loadings on B-As, L-As, K-As, and K-SOD, whereas PC3 showed high loadings on B-Pb, L-Pb, and K-Pb and accounted for 19.04% of the total variance.	Potassium	81-85	minisatellite 6 hypermutable 3	Mus musculus	0-3
32054691-9	2020	This receptor directly regulates pendrin"s total abundance and its relative abundance in the apical membrane region over a wide range in serum potassium concentration.	Potassium	143-152	solute carrier family 26, member 4	Mus musculus	33-40
31916164-16	2020	PC2 accounted for 23.81% of the total variance with high loadings on B-As, L-As, K-As, and K-SOD, whereas PC3 showed high loadings on B-Pb, L-Pb, and K-Pb and accounted for 19.04% of the total variance.	Potassium	150-154	proprotein convertase subtilisin/kexin type 1	Mus musculus	106-109
31557540-1	2020	BACKGROUND: KCNH2 encodes the human ether-a-go-go-related gene (hERG) potassium channel, which passes the rapid delayed rectifier potassium current, IKr.	Potassium	70-79	potassium voltage-gated channel subfamily H member 2	Homo sapiens	12-17
31557540-1	2020	BACKGROUND: KCNH2 encodes the human ether-a-go-go-related gene (hERG) potassium channel, which passes the rapid delayed rectifier potassium current, IKr.	Potassium	70-79	ETS transcription factor ERG	Homo sapiens	64-68
31557540-1	2020	BACKGROUND: KCNH2 encodes the human ether-a-go-go-related gene (hERG) potassium channel, which passes the rapid delayed rectifier potassium current, IKr.	Potassium	130-139	potassium voltage-gated channel subfamily H member 2	Homo sapiens	12-17
31557540-1	2020	BACKGROUND: KCNH2 encodes the human ether-a-go-go-related gene (hERG) potassium channel, which passes the rapid delayed rectifier potassium current, IKr.	Potassium	130-139	ETS transcription factor ERG	Homo sapiens	64-68
32054691-6	2020	With high circulating aldosterone, intercalated cell mineralocorticoid receptor gene ablation directly reduced pendrin"s relative abundance in the apical membrane region and pendrin abundance per cell whether serum potassium was high or low.	Potassium	215-224	nuclear receptor subfamily 3, group C, member 2	Mus musculus	53-79
32271402-3	2020	This study aimed to elucidate the mechanism of Potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) in osteogenic differentiation.	Potassium	47-56	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	126-134
30819023-5	2020	We found that only alpha2 heterozygous mice displayed higher SD susceptibility when challenged with prolonged extracellular high potassium concentration ([K+]o), a pronounced post SD oligemia and higher SD speed in-vivo.	Potassium	129-138	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	19-25
31907964-2	2020	Recent investigations have revealed that this syndrome is caused by mutations of ABCC9, which encodes a regulatory subunit of SUR2, an adenosine triphosphate-mediated potassium channel opener, expressed not only in smooth muscle but also in hair follicles.	Potassium	167-176	ATP binding cassette subfamily C member 9	Homo sapiens	81-86
31907964-2	2020	Recent investigations have revealed that this syndrome is caused by mutations of ABCC9, which encodes a regulatory subunit of SUR2, an adenosine triphosphate-mediated potassium channel opener, expressed not only in smooth muscle but also in hair follicles.	Potassium	167-176	ATP binding cassette subfamily C member 9	Homo sapiens	126-130
31997675-7	2020	The developmental time course of tagged Kv1-4 channel expression corresponds with previously published data on developmental changes in single neuron physiology, thus indicating that protein trap fly strains are a useful tool to analyze developmental regulation of potassium channel expression.	Potassium	265-274	Shaker	Drosophila melanogaster	40-45
31390869-2	2020	However, the role of lncRNA potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) in AML progression and its mechanism remain largely unknown.	Potassium	28-37	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	107-115
32111087-2	2020	AQP4 is densely expressed in astrocyte end-feet, and is an important factor in CNS water and potassium homeostasis.	Potassium	93-102	aquaporin 4	Homo sapiens	0-4
31984981-1	2020	The reaction of the potassium aluminyl K[Al(NONDipp)] (NONDipp = [O(SiMe2NDipp)2]2-, Dipp = 2,6-iPr2C6H3) with an organic azide generates the aluminium imide complex, K[Al(NONDipp)(NMes)] (Mes = mesityl = 2,4,6-Me3C6H2).	Potassium	20-53	nudix hydrolase 4	Homo sapiens	85-93
31838022-5	2020	Specifically, we demonstrate that miR-K12-6-5p, an oncoviral mimic of the tumor suppressive miR-15/16 family encoded by human Kaposi sarcoma-associated herpes virus, harbors a noncanonical toxic 6mer seed (position 3-8) and that v-miRNAs are more likely than cellular miRNAs to utilize a noncanonical 6mer seed.	Potassium	38-46	membrane associated ring-CH-type finger 8	Homo sapiens	34-37
31838022-5	2020	Specifically, we demonstrate that miR-K12-6-5p, an oncoviral mimic of the tumor suppressive miR-15/16 family encoded by human Kaposi sarcoma-associated herpes virus, harbors a noncanonical toxic 6mer seed (position 3-8) and that v-miRNAs are more likely than cellular miRNAs to utilize a noncanonical 6mer seed.	Potassium	38-46	membrane associated ring-CH-type finger 8	Homo sapiens	92-95
32070382-2	2020	The large-conductance Ca2+-activated potassium channels, or BKCa channels, are ubiquitously expressed throughout the central nervous system including the cingulate cortex.	Potassium	37-46	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	60-64
32093314-0	2020	Characterization of Convergent Suppression by UCL-2077 (3-(Triphenylmethylaminomethyl)pyridine), Known to Inhibit Slow Afterhyperpolarization, of erg-Mediated Potassium Currents and Intermediate-Conductance Calcium-Activated Potassium Channels.	Potassium	159-168	ETS transcription factor ERG	Rattus norvegicus	24-27
32306673-1	2020	Objective: The purpose of this study was to explore the association between gene in the potassium recycling pathway 4 (KCNQ4) polymorphisms and the susceptibility to noise-induced hearing loss (NIHL) , and analysis the effect of cumulative noise exposure (CNE) and noise exposure duration on this association.	Potassium	88-97	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	119-124
31699162-9	2020	Results indicated that KGM, inulin and K+I significantly increased the mucosal layer thickness, mucin density (granule number/crypt) and gene expression of Muc2 as compared with the control.	Potassium	39-42	mucin 2	Mus musculus	156-160
31945449-6	2020	As demonstrated through patch clamp recordings, high Atoh1 expression was associated with significantly decreased proportions of cells with Ih currents, significantly reduced proportions of transient potassium channel currents, and potassium channel currents with a greatly increased mean amplitude, which indicated that EHCLCs with high Atoh1 expression were more mature than those with low Atoh1 expression.	Potassium	200-209	atonal bHLH transcription factor 1	Rattus norvegicus	53-58
31945449-6	2020	As demonstrated through patch clamp recordings, high Atoh1 expression was associated with significantly decreased proportions of cells with Ih currents, significantly reduced proportions of transient potassium channel currents, and potassium channel currents with a greatly increased mean amplitude, which indicated that EHCLCs with high Atoh1 expression were more mature than those with low Atoh1 expression.	Potassium	232-241	atonal bHLH transcription factor 1	Rattus norvegicus	53-58
31992638-7	2020	As a result, we identified more than 5,000 putative target sites of osmotic stress-activated SnRK2.4 and SnRK2.6, abscisic acid-activated protein kinases SnRK2.6 and casein kinase 1-like 2 (CKL2), elicitor-activated protein kinase CDPK11 and MPK6, cold-activated protein kinase MPK6, H2O2-activated protein kinase OXI1 and MPK6, and salt-induced protein kinase SOS1 and MPK6, as well as the low-potassium-activated protein kinase CIPK23.	Potassium	395-404	SOS Ras/Rac guanine nucleotide exchange factor 1	Homo sapiens	361-365
32024761-5	2020	Here we experimentally assembled excitable membranes using the dynamic clamp and voltage-gated potassium ionic channels (Kv1.3) expressed in Xenopus oocytes.	Potassium	95-104	potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog	Xenopus laevis	121-126
31887021-1	2020	Krokinobacter rhodopsin 2 (KR2) serves as a light-driven sodium ion pump in the presence of sodium ion and works as a proton pump in the presence of larger monovalent cations such as potassium ion, rubidium ion, and cesium ion.	Potassium	183-192	rhodopsin	Homo sapiens	14-23
31974304-9	2020	Potassium channels in parvalbumin-type models deactivate rapidly and are unavailable for further modulation.	Potassium	0-9	parvalbumin	Homo sapiens	22-33
31765512-4	2020	We were able to tune the strength of the mica-organothiol interactions by exchanging the potassium surface ions for copper ions.	Potassium	89-98	MHC class I polypeptide-related sequence A	Homo sapiens	41-45
31913688-9	2020	All together, our results showed that the absence of the HKA2 during gestation leads to an "underfilled" situation and established this transporter as a key player of the renal control of salt and potassium metabolism during gestation.	Potassium	197-206	keratin 32	Mus musculus	57-61
31834838-1	2020	The cardiac potassium IKs current is carried by a channel complex formed from a-subunits encoded by KCNQ1 and b-subunits encoded by KCNE1.	Potassium	12-21	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	100-105
31834838-1	2020	The cardiac potassium IKs current is carried by a channel complex formed from a-subunits encoded by KCNQ1 and b-subunits encoded by KCNE1.	Potassium	12-21	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	132-137
31950953-7	2020	The potassium salt 5 was tested for its detonation ability by detonating RDX.	Potassium	4-13	radixin	Homo sapiens	73-76
32056680-5	2020	DRAD (%) results from the subtraction of potassium from uranium residual values.	Potassium	41-50	EGF containing fibulin extracellular matrix protein 1	Homo sapiens	0-4
31756511-0	2020	Human ether-a-go-go-related potassium channel: exploring SAR to improve drug design.	Potassium	28-37	sarcosine dehydrogenase	Homo sapiens	57-60
32016907-3	2020	Angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers (ACE/ARB), diuretics, and proton pump inhibitor (PPI) can interfere with potassium levels in these patients.	Potassium	151-160	angiotensin I converting enzyme	Homo sapiens	79-82
31444588-11	2020	The high positive loadings of PC1 (Cl-, TDS, SO42-, Na+, NO3-, Mg2+ and HCO3-) stand for processes of silicate weathering and dissolution, ion exchange and evaporation, and the influence of domestic waste waters, irrigation return flows and chemical fertilizers on the groundwater system, the PC2 (F- and pH) signifies the alkaline nature of groundwater, which causes fluorosis, and the PC3 (K+) is a result of potassium fertilizers.	Potassium	411-420	proprotein convertase subtilisin/kexin type 1	Homo sapiens	30-33
31837324-1	2020	Our study proposed to investigate the function of potassium voltage-gated channel sub-family Q member 1 opposite strand 1 (KCNQ1OT1) in cerebral ischemia-reperfusion (I/R) injury and the underlying mechanism.	Potassium	50-59	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	123-131
32010303-13	2020	Furthermore, a high concentration of potassium ions significantly reduced the secretion of IL-1beta after induction/stimulation.	Potassium	37-46	interleukin 1 alpha	Homo sapiens	91-99
31908037-7	2020	Paradoxically, CTRP1-deficient mice had elevated urinary sodium and potassium excretion, partially resulting from reduced expression of genes involved in renal sodium and potassium reabsorption.	Potassium	171-180	C1q and tumor necrosis factor related protein 1	Mus musculus	15-20
31908015-9	2020	Feeding nephrotic mice with a low potassium diet prevented hyperkaliemia, gamma-ENaC cleavage, and led to persistent increased phosphorylation of NCC.	Potassium	34-43	sodium channel, nonvoltage-gated 1 gamma	Mus musculus	74-84
31908037-7	2020	Paradoxically, CTRP1-deficient mice had elevated urinary sodium and potassium excretion, partially resulting from reduced expression of genes involved in renal sodium and potassium reabsorption.	Potassium	68-77	C1q and tumor necrosis factor related protein 1	Mus musculus	15-20
31646445-3	2020	Accumulating investigations imply that chloride efflux-dependent ASC speck oligomerization and potassium efflux-dependent activation of caspase-1 are the two relatively independent, but indispensable events for NLRP3 inflammasome activation.	Potassium	95-104	caspase 1	Homo sapiens	136-145
31646445-3	2020	Accumulating investigations imply that chloride efflux-dependent ASC speck oligomerization and potassium efflux-dependent activation of caspase-1 are the two relatively independent, but indispensable events for NLRP3 inflammasome activation.	Potassium	95-104	NLR family pyrin domain containing 3	Homo sapiens	211-216
31646445-4	2020	Previous studies suggested that influence of MCC950 on potassium efflux and its consequent events such as interaction between NEK7 and NLRP3 are limited.	Potassium	55-64	NIMA related kinase 7	Homo sapiens	126-130
31646445-4	2020	Previous studies suggested that influence of MCC950 on potassium efflux and its consequent events such as interaction between NEK7 and NLRP3 are limited.	Potassium	55-64	NLR family pyrin domain containing 3	Homo sapiens	135-140
32016907-3	2020	Angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers (ACE/ARB), diuretics, and proton pump inhibitor (PPI) can interfere with potassium levels in these patients.	Potassium	151-160	ATPase H+/K+ transporting subunit alpha	Homo sapiens	104-115
31851553-1	2020	KCNMA1, encoding the voltage- and calcium-activated potassium channel, has a pivotal role in brain physiology.	Potassium	52-61	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	0-6
32227763-9	2020	RESULTS: The expression of the autophagy-related protein LC3-II was increased and the expression of p62 was decreased in the BS-KS intervention group.	Potassium	128-130	nucleoporin 62	Mus musculus	100-103
32118778-1	2020	BACKGROUND: Vonoprazan is a potassium-competitive acid blocker (P-CAB) that is frequently used in Japan for Helicobacter pylori (H. pylori) eradication, treatment of gastroesophageal reflux disease, and treatment of post endoscopic submucosal dissection (ESD) complications.	Potassium	28-37	neural proliferation, differentiation and control 1	Homo sapiens	66-69
31668450-0	2020	Potassium Binders for Hyperkalemia in Chronic Kidney Disease-Diet, Renin-Angiotensin-Aldosterone System Inhibitor Therapy, and Hemodialysis.	Potassium	0-9	renin	Homo sapiens	67-72
31748680-5	2020	VEGF (1000 pg/mL) increased the nonselective cation current (INSC) of transient receptor potential (TRP) channels and potassium current of intermediate-conductance Ca2+-activated K+ (KCa3.1) channels thereby upregulating Ca2+ entry.	Potassium	118-127	vascular endothelial growth factor A	Homo sapiens	0-4
31870500-0	2020	Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion.	Potassium	45-54	potassium inwardly-rectifying channel, subfamily J, member 15	Mus musculus	38-44
31870500-2	2020	Here we evaluated the role of the inwardly rectifying potassium channel subunit Kir4.2 (Kcnj15 gene product) in this process.	Potassium	54-63	potassium inwardly-rectifying channel, subfamily J, member 15	Mus musculus	80-86
31870500-2	2020	Here we evaluated the role of the inwardly rectifying potassium channel subunit Kir4.2 (Kcnj15 gene product) in this process.	Potassium	54-63	potassium inwardly-rectifying channel, subfamily J, member 15	Mus musculus	88-94
31870500-6	2020	Additionally, Kcnj15 deletion depolarized the proximal cell membrane by decreasing the barium-sensitive component of the potassium conductance and caused an intracellular alkalinization.	Potassium	121-130	potassium inwardly-rectifying channel, subfamily J, member 15	Mus musculus	14-20
31870500-7	2020	Thus, the Kir4.2 potassium channel subunit is a newly recognized regulator of proximal ammonia metabolism.	Potassium	17-26	potassium inwardly-rectifying channel, subfamily J, member 15	Mus musculus	10-16
31669150-7	2020	Compared with controls, MIF-treated HL-1 myocytes had increased calcium transients, sarcoplasmic reticulum (SR) calcium content, Na+/Ca2+ exchanger (NCX) efflux rate, calcium leak, transient outward potassium current, and ultra-rapid delayed rectifier potassium current.	Potassium	199-208	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	24-27
31468337-6	2020	Finally, we ran a computational model combining the well-known reduction of potassium current by ghrelin with the CaV3 biophysical parameter modifications induced by ghrelin to predict the impact on neuronal electrical behavior.	Potassium	76-85	ghrelin	Mus musculus	97-104
31468337-10	2020	Our model-based prediction indicates that the inhibition of CaV3.3 would attenuate the stimulation of firing originating from the inhibition of potassium currents by ghrelin.	Potassium	144-153	caveolin 3	Homo sapiens	60-64
31468337-10	2020	Our model-based prediction indicates that the inhibition of CaV3.3 would attenuate the stimulation of firing originating from the inhibition of potassium currents by ghrelin.	Potassium	144-153	ghrelin	Mus musculus	166-173
32109341-5	2020	SPAK2 and KS-SPAK function to inhibit phosphorylation of cation co-transporters by full length SPAK.	Potassium	10-12	serine/threonine kinase 39	Mus musculus	13-17
32109341-6	2020	However, the existence of orthologous SPAK2 or KS-SPAK within the human kidney, and the role of such SPAK isoforms in nephron segment-specific regulation of Na+ reabsorption, still have not been determined.	Potassium	47-49	serine/threonine kinase 39	Homo sapiens	50-54
31757575-0	2020	High potassium exposure reveals the altered ability of astrocytes to regulate their volume in the aged hippocampus of GFAP/EGFP mice.	Potassium	5-14	glial fibrillary acidic protein	Mus musculus	118-122
31971671-0	2020	ZIF-8@ZIF-67-Derived Nitrogen-Doped Porous Carbon Confined CoP Polyhedron Targeting Superior Potassium-Ion Storage.	Potassium	93-102	caspase recruitment domain family member 16	Homo sapiens	59-62
31669150-7	2020	Compared with controls, MIF-treated HL-1 myocytes had increased calcium transients, sarcoplasmic reticulum (SR) calcium content, Na+/Ca2+ exchanger (NCX) efflux rate, calcium leak, transient outward potassium current, and ultra-rapid delayed rectifier potassium current.	Potassium	252-261	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	24-27
32019062-0	2020	Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice.	Potassium	36-45	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	29-35
31996484-4	2020	We report that the US Food and Drug Administration-approved potassium channel blocker 3,4-diaminopyridine (3,4-DAP) reverses respiratory depression and neuromuscular weakness in murine models of acute and chronic botulism.	Potassium	60-69	death-associated protein	Mus musculus	111-114
31654662-0	2020	ASP2905, a specific inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3 gene, is psychoactive in mice and rats.	Potassium	37-46	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	55-61
31654662-0	2020	ASP2905, a specific inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3 gene, is psychoactive in mice and rats.	Potassium	37-46	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	77-82
31654662-2	2020	In this study, we used animal models of behavior to evaluate the antipsychotic activity of ASP2905, a potent and selective inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.	Potassium	140-149	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	158-164
31654662-2	2020	In this study, we used animal models of behavior to evaluate the antipsychotic activity of ASP2905, a potent and selective inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.	Potassium	140-149	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	180-185
32019062-3	2020	Hyperglycemia downregulates inwardly rectifying potassium channel 4.1 (Kir4.1) in cultured astrocytes.	Potassium	48-57	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	71-77
32019062-6	2020	In diabetic mice, astrocytic Kir4.1 channels were functionally downregulated as evidenced by multiple characteristics including depolarized membrane potential, reduced barium-sensitive Kir currents and impaired potassium uptake capabilities of hippocampal astrocytes.	Potassium	211-220	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	29-35
31974459-4	2020	Recently, we have suggested that TRPML1-mediated lysosomal exocytosis is essentially dependent on lysosomal big conductance Ca2+-activated potassium (BK) channel.	Potassium	139-148	mucolipin 1	Mus musculus	33-39
31973216-4	2020	Ether a-go-go-1 (Eag1) is a voltage-gated potassium channel involved in cancer.	Potassium	42-51	potassium voltage-gated channel subfamily H member 1	Homo sapiens	0-15
31880435-9	2020	Preliminary 59Co NMR experiments show that the K+ ion in [K   {Co2(Lcat)3}](PF6) can be removed by its competitive complexation with the highly potassium-selective [2.2.2]cryptand, to give a transient 59Co NMR signal of the relatively unstable "empty" {Co2(Lcat)3} complex, which slowly decomposes in solution.	Potassium	144-153	sperm associated antigen 17	Homo sapiens	76-79
31973216-4	2020	Ether a-go-go-1 (Eag1) is a voltage-gated potassium channel involved in cancer.	Potassium	42-51	potassium voltage-gated channel subfamily H member 1	Homo sapiens	17-21
31992966-2	2019	The voltage-gated potassium Kv1.3 channel is of interest, which is considered as a novel therapeutic target for treating neuroinflammatory disorders due to its crucial role in subsets of T lymphocytes as well as microglial cells.	Potassium	18-27	potassium voltage-gated channel subfamily A member 3	Homo sapiens	28-33
31948476-0	2020	The ERG1a potassium channel increases basal intracellular calcium concentration and calpain activity in skeletal muscle cells.	Potassium	10-19	potassium voltage-gated channel subfamily H member 2	Homo sapiens	4-8
32038177-0	2020	The Epilepsy of Infancy With Migrating Focal Seizures: Identification of de novo Mutations of the KCNT2 Gene That Exert Inhibitory Effects on the Corresponding Heteromeric KNa1.1/KNa1.2 Potassium Channel.	Potassium	186-195	potassium sodium-activated channel subfamily T member 2	Homo sapiens	98-103
32038177-3	2020	KCNT1 and KCNT2 respectively encode the KNa1.1 (Slack) and KNa1.2 (Slick) subunits of the sodium-dependent voltage-gated potassium channel KNa.	Potassium	121-130	potassium sodium-activated channel subfamily T member 1	Homo sapiens	0-5
32038177-3	2020	KCNT1 and KCNT2 respectively encode the KNa1.1 (Slack) and KNa1.2 (Slick) subunits of the sodium-dependent voltage-gated potassium channel KNa.	Potassium	121-130	potassium sodium-activated channel subfamily T member 2	Homo sapiens	10-15
31936011-11	2020	In all cases, the performance of maize hybrids was maximum under potassium application at 75 kg ha-1.	Potassium	65-74	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	96-100
31837329-2	2020	The aim is to explore the role of lncRNA potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) and associated novel mechanisms in the progression and chemoresistance of AML.	Potassium	41-50	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	120-128
31998284-6	2019	Furthermore, LPC induced pyroptosis in both cells and the activation of the inflammasome with IL-1beta secretion, which was dependent on potassium efflux and lysosomal damage in human monocytes.	Potassium	137-146	interleukin 1 alpha	Homo sapiens	94-102
32021205-4	2020	Previous studies have suggested that the aquaporin 4(AQP4) and inward rectifier potassium ion channel Kir4.1 (encoded by gene KCNJ10) may act in concert to adjust water homeostasis and concentration of potassium ions in extracellular spaces of the central nervous system.	Potassium	80-89	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	102-108
32021205-4	2020	Previous studies have suggested that the aquaporin 4(AQP4) and inward rectifier potassium ion channel Kir4.1 (encoded by gene KCNJ10) may act in concert to adjust water homeostasis and concentration of potassium ions in extracellular spaces of the central nervous system.	Potassium	80-89	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	126-132
31866458-6	2020	Blocked hypomethylation increases BMP4 expression and selectively upregulates H3 K4me3 on the Bmp4 promoter, which may explain the effects on HFSC quiescence, hair cycle, and injury repair.	Potassium	81-86	bone morphogenetic protein 4	Homo sapiens	94-98
31781711-6	2020	Then, we find that humidity improves the resistance of the layers to be squeezed-out and extends the range of loads in which the liquid behaves as a superlubricant, interpreted by an enhanced dissolution of the potassium ions on the mica leading to a larger surface charge.	Potassium	211-220	MHC class I polypeptide-related sequence A	Homo sapiens	233-237
31744859-0	2020	Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.	Potassium	72-81	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	83-89
31691389-2	2020	The photochemical reactions allow the regiospecific and innate late-stage functionalization of helicenes and are easily executed either via the activation of C(sp2)-Br bonds in helicenes using K2CO3 as inorganic base or direct C(sp2)-H helicene bond functionalization under oxidative photoredox reaction conditions.	Potassium	193-198	Sp2 transcription factor	Homo sapiens	158-163
32291375-2	2020	However, RAAS inhibitors (angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, aldosterone receptor antagonists, and direct renin inhibitors) increase the risk of hyperkalemia (serum potassium >5.5 mmol/L).	Potassium	203-212	renin	Homo sapiens	144-149
31919307-8	2020	Three target proteins, i.e. human ether-a-go-go-related (hERG) potassium channel, the inhibitor of apoptosis protein 3 and serine/threonine-protein kinase PIM1, were chosen as the targets.	Potassium	63-72	ETS transcription factor ERG	Homo sapiens	57-61
32477601-4	2020	In the kidneys of non-anesthetized rats, which received a water load of 2 ml per 100 g of body weight, three effects of vasopressin were revealed: 1) increased reabsorption of water and sodium, 2) increased excretion of potassium ions, and 3) increased excretion of sodium ions.	Potassium	220-229	arginine vasopressin	Rattus norvegicus	120-131
31810890-1	2020	Analogues of the anti-tuberculosis drug bedaquiline, bearing a 3,5-dimethoxy-4-pyridyl C-unit, retain high anti-bacterial potency yet exert less inhibition of the hERG potassium channel, in vitro, than the parent compound.	Potassium	168-177	ETS transcription factor ERG	Homo sapiens	163-167
31839145-1	2020	Kv11.1 potassium channels are essential for heart repolarization.	Potassium	7-16	potassium voltage-gated channel modifier subfamily V member 2	Homo sapiens	0-6
31642335-4	2020	Protein inhibitor of activated STAT3 (PIAS3) promoted SUMO1 conjugation at K725 and K739 on nNOS, which upregulated NO production and nNOS S1412 phosphorylation (activation).	Potassium	84-88	protein inhibitor of activated STAT 3	Homo sapiens	0-36
31642335-4	2020	Protein inhibitor of activated STAT3 (PIAS3) promoted SUMO1 conjugation at K725 and K739 on nNOS, which upregulated NO production and nNOS S1412 phosphorylation (activation).	Potassium	84-88	protein inhibitor of activated STAT 3	Homo sapiens	38-43
31642335-4	2020	Protein inhibitor of activated STAT3 (PIAS3) promoted SUMO1 conjugation at K725 and K739 on nNOS, which upregulated NO production and nNOS S1412 phosphorylation (activation).	Potassium	84-88	nitric oxide synthase 1	Homo sapiens	92-96
31642335-4	2020	Protein inhibitor of activated STAT3 (PIAS3) promoted SUMO1 conjugation at K725 and K739 on nNOS, which upregulated NO production and nNOS S1412 phosphorylation (activation).	Potassium	84-88	nitric oxide synthase 1	Homo sapiens	134-138
31653347-6	2020	Incubation with beta-d-glucose was associated with glycation of 4 (K-418, K-427, K-434, K-441) out of 6 lysine residues, known to be important for mediating the interaction with plasmin.	Potassium	88-93	plasminogen	Homo sapiens	178-185
33092407-0	2020	Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na+/K+ ATPase and Occurs Independently of Aquaporin 4.	Potassium	62-71	aquaporin 4	Homo sapiens	144-155
33307724-0	2020	Erratum to "Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na+/K+ ATPase and Occurs Independently of Aquaporin 4".	Potassium	74-83	aquaporin 4	Homo sapiens	156-167
33349065-5	2020	In this article, we present the case of a 47-year-old woman with Bartter syndrome on oral potassium 40 mg BID (twice a day) and magnesium oxide 800 TID (thrice a day), who recently had a small bowel resection that required intravenous potassium and magnesium throughout her hospital admission.	Potassium	90-99	BH3 interacting domain death agonist	Homo sapiens	106-109
31657676-1	2020	The human ether-a-go-go-related gene (hERG) potassium channel is the rapidly activating component of cardiac delayed rectifier potassium current (IKr), which is a crucial determinant of cardiac repolarization.	Potassium	44-53	ETS transcription factor ERG	Homo sapiens	38-42
31657676-1	2020	The human ether-a-go-go-related gene (hERG) potassium channel is the rapidly activating component of cardiac delayed rectifier potassium current (IKr), which is a crucial determinant of cardiac repolarization.	Potassium	127-136	ETS transcription factor ERG	Homo sapiens	38-42
30897577-0	2020	Efficacy of Vonoprazan, a Novel Potassium-Competitive Acid Blocker, in Patients with Proton Pump Inhibitor-Refractory Acid Reflux.	Potassium	32-41	ATPase H+/K+ transporting subunit alpha	Homo sapiens	85-96
31914597-1	2020	The Slack (KCNT1) gene encodes sodium-activated potassium channels that are abundantly expressed in the central nervous system.	Potassium	48-57	potassium sodium-activated channel subfamily T member 1	Homo sapiens	4-9
31914597-1	2020	The Slack (KCNT1) gene encodes sodium-activated potassium channels that are abundantly expressed in the central nervous system.	Potassium	48-57	potassium sodium-activated channel subfamily T member 1	Homo sapiens	11-16
32491968-2	2020	Therefore, we sought to clarify whether MD1 can alter the electrophysiological remodeling of cardiac myocytes from obese mice by regulating voltage-gated potassium current and calcium current.	Potassium	154-163	lymphocyte antigen 86	Mus musculus	40-43
32491968-10	2020	MD1 deletion led to down-regulated potassium currents and slowed inactivation of L-type calcium channel in an obese mice model.	Potassium	35-44	lymphocyte antigen 86	Mus musculus	0-3
31560448-5	2020	Multivariate linear regression showed that the AGT rs699 and CYP11B2 rs1799998 polymorphisms plus baseline serum potassium explained 71% of variability in LVEF improvement (p=0.001), 63% of variability in serum potassium increase (p=2.25E-08), and 39% of the variability in improvement in quality of life (p=2.3E-04) with spironolactone therapy.	Potassium	211-220	angiotensinogen	Homo sapiens	47-50
31599747-6	2020	Novel nonsteroidal mineralocorticoid receptor antagonists (MRA) are able to lower proteinuria and markers of heart failure, with limited potassium problems and without renal impairment.	Potassium	137-146	nuclear receptor subfamily 3 group C member 2	Homo sapiens	19-45
32611299-2	2020	In a previous study, we discovered that zacopride selectively stimulated the inward rectifier potassium current (IK1) in the rat and that agonizing IK1 prevented or eliminated aconitine-induced arrhythmias inrats.	Potassium	94-103	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	113-116
31932120-5	2020	Key potassium channelopathies include those affecting the KV, KCa and Kir families, a significant proportion of which have been implicated in neurological disease.	Potassium	4-13	casein kappa	Homo sapiens	62-65
31932120-5	2020	Key potassium channelopathies include those affecting the KV, KCa and Kir families, a significant proportion of which have been implicated in neurological disease.	Potassium	4-13	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	70-73
31730936-4	2020	This emphasizes the pharmacologic properties necessary for TdP but does not account for situations where clinical exposure may be higher, or where hERG potassium channel active metabolites are involved.	Potassium	152-161	ETS transcription factor ERG	Homo sapiens	147-151
31785237-1	2020	The slow voltage-gated potassium channel (IKs) is composed of the KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart.	Potassium	23-32	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	66-71
31785237-1	2020	The slow voltage-gated potassium channel (IKs) is composed of the KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart.	Potassium	23-32	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	76-81
31897736-1	2020	Kv10.1 (Eag1, or KCNH1) is a human potassium-selective channel associated with tumor development.	Potassium	35-44	potassium voltage-gated channel subfamily H member 1	Homo sapiens	0-6
31578829-6	2020	Among the other probands, missense SNVs were observed in DCLK2 (Doublecortin Like Kinase 2), HERC2 (HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2), and KCNH3 (Potassium channel, voltage-gated, subfamily H, member 3).	Potassium	174-183	doublecortin like kinase 2	Homo sapiens	57-62
31819014-11	2020	Existing data suggest that I3 receptors may represent a binding site at the Kir6.2-subtype ATP-sensitive potassium channels in pancreatic beta-cells and may be involved in insulin secretion.	Potassium	105-114	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	76-82
31782079-0	2020	Zinc finger protein 5 (ZFP5) associates with ethylene signaling to regulate the phosphate and potassium deficiency-induced root hair development in Arabidopsis.	Potassium	94-103	zinc finger protein 5	Arabidopsis thaliana	0-21
31782079-0	2020	Zinc finger protein 5 (ZFP5) associates with ethylene signaling to regulate the phosphate and potassium deficiency-induced root hair development in Arabidopsis.	Potassium	94-103	zinc finger protein 5	Arabidopsis thaliana	23-27
31782079-1	2020	KEY MESSAGE: Zinc finger protein transcription factor ZFP5 positively regulates root hair elongation in response to Pi and potassium deficiency by mainly activating the expression of EIN2 in Arabidopsis.	Potassium	123-132	zinc finger protein 5	Arabidopsis thaliana	54-58
31782079-1	2020	KEY MESSAGE: Zinc finger protein transcription factor ZFP5 positively regulates root hair elongation in response to Pi and potassium deficiency by mainly activating the expression of EIN2 in Arabidopsis.	Potassium	123-132	NRAMP metal ion transporter family protein	Arabidopsis thaliana	183-187
31782079-7	2020	The significant reduction of root hair length in ein2-1 and ein3-1 as compared to wild-type under Pi and potassium deficiency supports the involvement of ethylene in root hair elongation.	Potassium	105-114	NRAMP metal ion transporter family protein	Arabidopsis thaliana	49-53
31782079-7	2020	The significant reduction of root hair length in ein2-1 and ein3-1 as compared to wild-type under Pi and potassium deficiency supports the involvement of ethylene in root hair elongation.	Potassium	105-114	Ethylene insensitive 3 family protein	Arabidopsis thaliana	60-64
31782079-8	2020	Furthermore, the application of 1-aminocyclopropane-1-carboxylic acid (ACC) significantly enhanced the expression level of ZFP5 while the application of 2-aminoethoxyvinyl glycine (AVG) had the opposite effect when either Pi or potassium was deprived.	Potassium	228-237	zinc finger protein 5	Arabidopsis thaliana	123-127
31782079-10	2020	Generally, these results suggest that ZFP5 regulates root hair elongation by interacting with ethylene signaling mainly through regulates the expression of EIN2 in response to Pi and potassium deficiency in Arabidopsis.	Potassium	183-192	zinc finger protein 5	Arabidopsis thaliana	38-42
31782079-10	2020	Generally, these results suggest that ZFP5 regulates root hair elongation by interacting with ethylene signaling mainly through regulates the expression of EIN2 in response to Pi and potassium deficiency in Arabidopsis.	Potassium	183-192	NRAMP metal ion transporter family protein	Arabidopsis thaliana	156-160
31897736-1	2020	Kv10.1 (Eag1, or KCNH1) is a human potassium-selective channel associated with tumor development.	Potassium	35-44	potassium voltage-gated channel subfamily H member 1	Homo sapiens	8-12
31897736-1	2020	Kv10.1 (Eag1, or KCNH1) is a human potassium-selective channel associated with tumor development.	Potassium	35-44	potassium voltage-gated channel subfamily H member 1	Homo sapiens	17-22
31919767-1	2020	The group of KCNQ-encoded voltage-gated potassium (Kv7) channels includes five family members (Kv7.1-7.5).	Potassium	40-49	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	95-100
32419412-0	2020	Increased potassium excretion in children with monosymptomatic nocturnal enuresis: could it be related to Kir 4.1- KCNJ10 gene polymorphism?	Potassium	10-19	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	106-113
31724744-8	2020	RESULTS: Extracellular potassium was greater in the irradiated conditions when compared to the nonirradiated controls and was greater in the post-CIG group when compared to the pre-CIG group (p < 0.05).	Potassium	23-32	fibronectin 1	Homo sapiens	146-149
31724744-8	2020	RESULTS: Extracellular potassium was greater in the irradiated conditions when compared to the nonirradiated controls and was greater in the post-CIG group when compared to the pre-CIG group (p < 0.05).	Potassium	23-32	fibronectin 1	Homo sapiens	181-184
32419412-0	2020	Increased potassium excretion in children with monosymptomatic nocturnal enuresis: could it be related to Kir 4.1- KCNJ10 gene polymorphism?	Potassium	10-19	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	115-121
32419412-10	2020	CONCLUSION: We conclude that KCNJ10 gene promoter polymorphism may have a role on potassium excretion in Turkish MNE children.	Potassium	82-91	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	29-35
32835836-9	2020	Multiple regression analysis adjusted for age, body-mass index, and fibrinogen levels showed that anti-FXa activity, antithrombin activity, and FVIII activity determined Ks, while anti-FXa activity, plasminogen activator inhibitor-1 level, and presence of right ventricular dysfunction determined CLT.	Potassium	170-172	fibrinogen beta chain	Homo sapiens	68-78
31882877-3	2019	Here, we show that KCTD15, a member of the emerging class of KCTD ((K)potassium Channel Tetramerization Domain containing) proteins, is strongly upregulated in patients affected by B-cell type acute lymphoblastic leukemia (B-ALL) and in continuous cell lines (RS4;11, REH, TOM-1, SEM) derived from this form of childhood leukemia.	Potassium	70-79	potassium channel tetramerization domain containing 15	Homo sapiens	19-25
32835836-9	2020	Multiple regression analysis adjusted for age, body-mass index, and fibrinogen levels showed that anti-FXa activity, antithrombin activity, and FVIII activity determined Ks, while anti-FXa activity, plasminogen activator inhibitor-1 level, and presence of right ventricular dysfunction determined CLT.	Potassium	170-172	coagulation factor X	Homo sapiens	103-106
32835836-9	2020	Multiple regression analysis adjusted for age, body-mass index, and fibrinogen levels showed that anti-FXa activity, antithrombin activity, and FVIII activity determined Ks, while anti-FXa activity, plasminogen activator inhibitor-1 level, and presence of right ventricular dysfunction determined CLT.	Potassium	170-172	serpin family C member 1	Homo sapiens	117-129
32835836-9	2020	Multiple regression analysis adjusted for age, body-mass index, and fibrinogen levels showed that anti-FXa activity, antithrombin activity, and FVIII activity determined Ks, while anti-FXa activity, plasminogen activator inhibitor-1 level, and presence of right ventricular dysfunction determined CLT.	Potassium	170-172	coagulation factor VIII	Homo sapiens	144-149
31892729-1	2019	Ginsenoside Rb1 exerts its pharmacological action by regulating sodium, potassium and calcium ion channels in the membranes of nerve cells.	Potassium	72-81	RB transcriptional corepressor 1	Homo sapiens	12-15
31892729-5	2019	The results showed that Rb1 inhibited INa and ICaL, reduced the action potential amplitude (APA) and maximum upstroke velocity (Vmax), and shortened the action potential duration (APD) in a concentration-dependent manner but had no effect on the inward rectifier potassium current (IK1), delayed rectifier potassium current (IK) or resting membrane potential (RMP).	Potassium	263-272	RB transcriptional corepressor 1	Homo sapiens	24-27
31892729-5	2019	The results showed that Rb1 inhibited INa and ICaL, reduced the action potential amplitude (APA) and maximum upstroke velocity (Vmax), and shortened the action potential duration (APD) in a concentration-dependent manner but had no effect on the inward rectifier potassium current (IK1), delayed rectifier potassium current (IK) or resting membrane potential (RMP).	Potassium	306-315	RB transcriptional corepressor 1	Homo sapiens	24-27
31882877-3	2019	Here, we show that KCTD15, a member of the emerging class of KCTD ((K)potassium Channel Tetramerization Domain containing) proteins, is strongly upregulated in patients affected by B-cell type acute lymphoblastic leukemia (B-ALL) and in continuous cell lines (RS4;11, REH, TOM-1, SEM) derived from this form of childhood leukemia.	Potassium	70-79	target of myb1 membrane trafficking protein	Homo sapiens	273-278
31874991-3	2019	The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit underlying cardiac rapidly delayed rectifier potassium current (IKr).	Potassium	125-134	potassium voltage-gated channel subfamily H member 2	Homo sapiens	40-45
31882846-1	2019	The hERG potassium channel influences ventricular action potential duration.	Potassium	9-18	ETS transcription factor ERG	Homo sapiens	4-8
31863007-4	2019	Here, we identify PBRM1 as a reader for p53 acetylation on lysine 382 (K382Ac) through its bromodomain 4 (BD4).	Potassium	71-77	polybromo 1	Homo sapiens	18-23
31761909-0	2019	Prediction of two-dimensional PC6 as a promising anode material for potassium-ion batteries.	Potassium	68-77	proprotein convertase subtilisin/kexin type 5	Homo sapiens	30-33
31761909-8	2019	These appealing properties render the PC6 monolayer an excellent anode candidate for potassium-ion batteries.	Potassium	85-94	proprotein convertase subtilisin/kexin type 5	Homo sapiens	38-41
31799617-11	2019	These studies revealed that the knockout of Kcnj16 markedly altered RAAS regulation and function, suggesting Kir5.1 as a key regulator of the RAAS, particularly when exposed to changes in dietary sodium and potassium content.	Potassium	207-216	potassium inwardly-rectifying channel, subfamily J, member 16	Rattus norvegicus	44-50
31799617-11	2019	These studies revealed that the knockout of Kcnj16 markedly altered RAAS regulation and function, suggesting Kir5.1 as a key regulator of the RAAS, particularly when exposed to changes in dietary sodium and potassium content.	Potassium	207-216	potassium inwardly-rectifying channel, subfamily J, member 16	Rattus norvegicus	109-115
31863007-4	2019	Here, we identify PBRM1 as a reader for p53 acetylation on lysine 382 (K382Ac) through its bromodomain 4 (BD4).	Potassium	71-77	tumor protein p53	Homo sapiens	40-43
31863007-5	2019	Notably, mutations on key residues of BD4 disrupt recognition of p53 K382Ac.	Potassium	69-75	tumor protein p53	Homo sapiens	65-68
31863061-0	2019	The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK.	Potassium	56-65	uromodulin	Mus musculus	25-35
31863061-0	2019	The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK.	Potassium	56-65	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	74-78
31863061-2	2019	Uromodulin regulates the activity of the potassium channel ROMK in TAL cells.	Potassium	41-50	uromodulin	Mus musculus	0-10
31863061-2	2019	Uromodulin regulates the activity of the potassium channel ROMK in TAL cells.	Potassium	41-50	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	59-63
31863073-0	2019	Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion.	Potassium	101-110	CAP, adenylate cyclase-associated protein, 2 (yeast)	Mus musculus	32-36
31863073-0	2019	Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion.	Potassium	101-110	transmembrane protease, serine 4	Mus musculus	37-44
31861703-0	2019	Challenges Faced with Small Molecular Modulators of Potassium Current Channel Isoform Kv1.5.	Potassium	52-61	potassium voltage-gated channel subfamily A member 5	Homo sapiens	86-91
31892810-3	2019	On the other hand, whereas other inflammasomes are mainly detectors of specific molecular motifs, NLRP3 is acting as a general sensor of cellular perturbations including potassium efflux, lysosomal damage, and ROS production.	Potassium	170-179	NLR family pyrin domain containing 3	Homo sapiens	98-103
31861703-1	2019	The voltage-gated potassium channel Kv1.5, which mediates the cardiac ultra-rapid delayed-rectifier (IKur) current in human cells, has a crucial role in atrial fibrillation.	Potassium	18-27	potassium voltage-gated channel subfamily A member 5	Homo sapiens	36-41
31938690-2	2019	KATP channels were formed by potassium ion-passing pore-forming subunits (Kir6.1, Kir6.2) and regulatory subunits SUR1, SU2A and SUR2B.	Potassium	29-38	potassium inwardly-rectifying channel, subfamily J, member 8	Rattus norvegicus	74-80
31655646-4	2019	Surprisingly, a stable and strong ECL signal was obtained based on the RET, which was used for signal-off detection of FA in the presence of coreactant K2S2O8.	Potassium	152-158	ret proto-oncogene	Homo sapiens	71-74
31730143-8	2019	Through this chip based method, stable current recordings through inward rectifier potassium (Kir) ion channels embedded in rat basophilic leukemia (RBL-1) cell membrane are achieved with high electrical sealing resistance (over 1 GOmega).	Potassium	83-92	RB transcriptional corepressor like 1	Rattus norvegicus	149-154
31890149-4	2019	Whole-cell patch-clamp experiment showed that Ktx-Sp2 peptide could effectively block three types of exogenous voltage-gated potassium channels-Kv1.1, Kv1.2 and Kv1.3, among which, the blocking activity for Kv1.3 was relatively high, showing selectivity to some extent.	Potassium	125-134	potassium voltage-gated channel subfamily A member 1	Homo sapiens	144-149
31890149-4	2019	Whole-cell patch-clamp experiment showed that Ktx-Sp2 peptide could effectively block three types of exogenous voltage-gated potassium channels-Kv1.1, Kv1.2 and Kv1.3, among which, the blocking activity for Kv1.3 was relatively high, showing selectivity to some extent.	Potassium	125-134	potassium voltage-gated channel subfamily A member 2	Homo sapiens	151-156
31890149-4	2019	Whole-cell patch-clamp experiment showed that Ktx-Sp2 peptide could effectively block three types of exogenous voltage-gated potassium channels-Kv1.1, Kv1.2 and Kv1.3, among which, the blocking activity for Kv1.3 was relatively high, showing selectivity to some extent.	Potassium	125-134	potassium voltage-gated channel subfamily A member 3	Homo sapiens	161-166
31767767-5	2019	Here, we identify a detailed working mechanism of how the homeodomain-like transcription factor NSY-7, previously described as a repressor in the maintenance of AWC asymmetry, couples SLO BK potassium channels to transactivation of sox-2 expression for the induction of the AWCON subtype through the identification of a unique imb-2 (transportin 1) allele.	Potassium	191-200	SRY-box transcription factor 2	Homo sapiens	232-237
31669729-5	2019	In the present study, we investigated the functional effect of these variants on the potassium channel Kir2.1 and the significance of the double mutation.	Potassium	85-94	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	103-109
31767767-5	2019	Here, we identify a detailed working mechanism of how the homeodomain-like transcription factor NSY-7, previously described as a repressor in the maintenance of AWC asymmetry, couples SLO BK potassium channels to transactivation of sox-2 expression for the induction of the AWCON subtype through the identification of a unique imb-2 (transportin 1) allele.	Potassium	191-200	transportin 1	Homo sapiens	334-347
31767767-8	2019	This study provides mechanistic insight into how NSY-7 couples SLO BK potassium channels to transactivation of sox-2 expression for the induction of the AWCON subtype.	Potassium	70-79	SRY-box transcription factor 2	Homo sapiens	111-116
31835299-8	2019	In addition, ion analysis showed that opr7opr8 accumulated less sodium but more potassium in the leaves than WT but more sodium and less potassium in the roots than WT, suggesting that JA deficiency causes higher salt stress to the roots but less stress to the leaves of the seedlings.	Potassium	80-89	12-oxophytodienoate reductase7	Zea mays	38-46
31630908-3	2019	Here, we show that TREK-1 and TRAAK, the thermosensitive and mechanosensitive two-pore-domain potassium (K2P) channels, are clustered at NRs of rat trigeminal Abeta-afferent nerves with a density over 3,000-fold higher than that on their somas.	Potassium	94-103	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	19-25
31630908-3	2019	Here, we show that TREK-1 and TRAAK, the thermosensitive and mechanosensitive two-pore-domain potassium (K2P) channels, are clustered at NRs of rat trigeminal Abeta-afferent nerves with a density over 3,000-fold higher than that on their somas.	Potassium	94-103	potassium two pore domain channel subfamily K member 4	Rattus norvegicus	30-35
31630908-3	2019	Here, we show that TREK-1 and TRAAK, the thermosensitive and mechanosensitive two-pore-domain potassium (K2P) channels, are clustered at NRs of rat trigeminal Abeta-afferent nerves with a density over 3,000-fold higher than that on their somas.	Potassium	105-108	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	19-25
31630908-3	2019	Here, we show that TREK-1 and TRAAK, the thermosensitive and mechanosensitive two-pore-domain potassium (K2P) channels, are clustered at NRs of rat trigeminal Abeta-afferent nerves with a density over 3,000-fold higher than that on their somas.	Potassium	105-108	potassium two pore domain channel subfamily K member 4	Rattus norvegicus	30-35
31815668-1	2019	Up-regulation of the persistent sodium current (INaP) and down-regulation of the potassium/chloride extruder KCC2 lead to spasticity after spinal cord injury (SCI).	Potassium	81-90	solute carrier family 12 member 5	Rattus norvegicus	109-113
31701097-0	2019	In silico investigation of the interaction between the voltage-gated potassium channel Kv4.3 and its auxiliary protein KChIP1.	Potassium	69-78	potassium voltage-gated channel subfamily D member 3	Homo sapiens	87-92
31701097-0	2019	In silico investigation of the interaction between the voltage-gated potassium channel Kv4.3 and its auxiliary protein KChIP1.	Potassium	69-78	potassium voltage-gated channel interacting protein 1	Homo sapiens	119-125
31701097-1	2019	The voltage-gated potassium channel Kv4.3 plays a vital role in shaping the timing, frequency, and backpropagation of electrical signals in the brain and heart by generating fast transient currents at subthreshold membrane potentials in repetitive firing neurons.	Potassium	18-27	potassium voltage-gated channel subfamily D member 3	Homo sapiens	36-41
31701097-2	2019	To achieve its physiological function, Kv4.3 is assisted by auxiliary beta-subunits that become integral parts of the native A-type potassium channels, among which there are the Kv channel-interacting proteins (KChIPs).	Potassium	132-141	potassium voltage-gated channel subfamily D member 3	Homo sapiens	39-44
31600170-0	2019	KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern.	Potassium	6-15	potassium voltage-gated channel subfamily D member 3	Homo sapiens	0-5
31835299-8	2019	In addition, ion analysis showed that opr7opr8 accumulated less sodium but more potassium in the leaves than WT but more sodium and less potassium in the roots than WT, suggesting that JA deficiency causes higher salt stress to the roots but less stress to the leaves of the seedlings.	Potassium	137-146	12-oxophytodienoate reductase7	Zea mays	38-46
31810225-4	2019	In particular, TASK-3 (KCNK9), a member of the K2P potassium channel family, has attracted much interest because of its oncogenic properties.	Potassium	51-60	potassium two pore domain channel subfamily K member 9	Homo sapiens	23-28
31558613-6	2019	Inflammasome activation by PAF also requires potassium efflux and calcium influx but not lysosomal cathepsin or mitochondrial reactive oxygen species.	Potassium	45-54	PCNA clamp associated factor	Homo sapiens	27-30
31657247-5	2019	The increase in abundance of Na+/H+ exchanger 3 (NHE3) or activated Na+-K+-2Cl- cotransporter 2 (NKCC2-P) predicted significant reductions in urinary Na+ excretion, yet there was no observed change in urine Na+.	Potassium	72-78	solute carrier family 12 member 1	Rattus norvegicus	97-102
31664867-1	2019	There is significant interest in the potential utility of small molecule activator compounds to mitigate cardiac arrhythmia caused by loss-of-function of hERG1a voltage-gated potassium channels.	Potassium	175-184	potassium voltage-gated channel subfamily H member 2	Homo sapiens	154-159
31625414-3	2019	Here, we hypothesized that lncRNA potassium voltage-gated channel subfamily q member 1 overlapping transcript 1 (KCNQ1OT1) could affect the development of MI via regulation of Runt-related transcription factor (RUNX)3 by methylation.	Potassium	34-43	KCNQ1 overlapping transcript 1	Mus musculus	113-121
31742594-1	2019	The two-pore potassium channel, TRESK has been implicated in nociception and pain disorders.	Potassium	13-22	potassium two pore domain channel subfamily K member 18	Homo sapiens	32-37
31600826-1	2019	OBJECTIVE: Pathogenic variants in KCNB1, encoding the voltage-gated potassium channel KV 2.1, are associated with developmental and epileptic encephalopathy (DEE).	Potassium	68-77	potassium voltage-gated channel subfamily B member 1	Homo sapiens	34-39
31610034-14	2019	All three mutants cloned in Xenopus oocytes caused an aberrant modulation of the mechano-gated potassium channel, TREK-1.	Potassium	95-104	potassium channel, two pore domain subfamily K, member 2 S homeolog	Xenopus laevis	114-120
31190144-10	2019	Intraocular injection of potassium in wild-type mice led to visual function hyperactivity, as observed in Aqp4 KO mice.	Potassium	25-34	aquaporin 4	Mus musculus	106-110
31682765-0	2019	Complexes formed with integrin-alpha5 and KCNB1 potassium channel wild type or epilepsy-susceptibility variants modulate cellular plasticity via Ras and Akt signaling.	Potassium	48-57	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	42-47
31682765-0	2019	Complexes formed with integrin-alpha5 and KCNB1 potassium channel wild type or epilepsy-susceptibility variants modulate cellular plasticity via Ras and Akt signaling.	Potassium	48-57	thymoma viral proto-oncogene 1	Mus musculus	153-156
31682765-1	2019	Voltage-gated potassium (K+) channel subfamily B member 1 (KCNB1, Kv2.1) and integrin-alpha5 form macromolecular complexes-named integrin-alpha5-KCNB1 complexes (IKCs)-in the human brain, but their function was poorly understood.	Potassium	14-23	potassium voltage-gated channel subfamily B member 1	Homo sapiens	59-64
31682765-1	2019	Voltage-gated potassium (K+) channel subfamily B member 1 (KCNB1, Kv2.1) and integrin-alpha5 form macromolecular complexes-named integrin-alpha5-KCNB1 complexes (IKCs)-in the human brain, but their function was poorly understood.	Potassium	14-23	potassium voltage-gated channel subfamily B member 1	Homo sapiens	66-71
31682765-1	2019	Voltage-gated potassium (K+) channel subfamily B member 1 (KCNB1, Kv2.1) and integrin-alpha5 form macromolecular complexes-named integrin-alpha5-KCNB1 complexes (IKCs)-in the human brain, but their function was poorly understood.	Potassium	14-23	integrin subunit alpha 5	Homo sapiens	129-144
31682765-1	2019	Voltage-gated potassium (K+) channel subfamily B member 1 (KCNB1, Kv2.1) and integrin-alpha5 form macromolecular complexes-named integrin-alpha5-KCNB1 complexes (IKCs)-in the human brain, but their function was poorly understood.	Potassium	14-23	potassium voltage-gated channel subfamily B member 1	Homo sapiens	145-150
31638180-0	2019	Adipose-derived stem cells overexpressing SK4 calcium-activated potassium channel generate biological pacemakers.	Potassium	64-73	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	42-45
31612994-0	2019	Shaw and Shal voltage-gated potassium channels mediate circadian changes in Drosophila clock neuron excitability.	Potassium	28-37	Shaker cognate l	Drosophila melanogaster	9-13
31612994-4	2019	We show that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv4) oscillate in a circadian manner.	Potassium	52-61	Shaker cognate w	Drosophila melanogaster	71-75
31612994-4	2019	We show that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv4) oscillate in a circadian manner.	Potassium	52-61	Shaker cognate w	Drosophila melanogaster	77-80
31612994-4	2019	We show that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv4) oscillate in a circadian manner.	Potassium	52-61	Shaker cognate l	Drosophila melanogaster	86-90
31612994-4	2019	We show that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv4) oscillate in a circadian manner.	Potassium	52-61	Shaker cognate l	Drosophila melanogaster	92-95
31190144-12	2019	AQP4 may fine-tune synaptic activity, most likely by regulating potassium metabolism, at least in part, via collaborating with KIR2.1, and possibly indirectly regulating glutamate kinetics, to inhibit neural hyperactivity and synaptic fatigue which finally affect mitochondria and cause neurodegeneration.	Potassium	64-73	aquaporin 4	Mus musculus	0-4
31624998-0	2019	The Potassium Channel Kv1.5 Expression Alters During Experimental Autoimmune Encephalomyelitis.	Potassium	4-13	potassium voltage-gated channel subfamily A member 5	Rattus norvegicus	22-27
31624998-3	2019	It was shown that voltage-gated potassium channels Kv1.5 are responsible for fine-tuning in the immune physiology and influence proliferation and differentiation in microglia and astrocytes.	Potassium	32-41	potassium voltage-gated channel subfamily A member 5	Rattus norvegicus	51-56
31814333-9	2019	Finally, we demonstrate that DCPIB activates ATP-inhibitable potassium channels comprised of heterologously expressed Kir6.2 and SUR1 subunits.	Potassium	61-70	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	118-124
31832048-0	2019	The Shaker Type Potassium Channel, GORK, Regulates Abscisic Acid Signaling in Arabidopsis.	Potassium	16-25	gated outwardly-rectifying K+ channel	Arabidopsis thaliana	35-39
31814333-9	2019	Finally, we demonstrate that DCPIB activates ATP-inhibitable potassium channels comprised of heterologously expressed Kir6.2 and SUR1 subunits.	Potassium	61-70	ATP binding cassette subfamily C member 8	Homo sapiens	129-133
31832048-4	2019	In this study, we report that the shaker type potassium (K+) channel, GORK, modulates plant responses to ABA and abiotic stresses.	Potassium	46-55	gated outwardly-rectifying K+ channel	Arabidopsis thaliana	70-74
31795491-3	2019	The encoded proteins Kelch-like 3 and Cullin 3 interact to form a ring-like complex to ubiquitinate WNK-kinase 4, which, in normal circumstances, interacts with the sodium chloride co-symporter (NCC), the epithelial sodium channel (ENaC), and the renal outer medullary potassium channel (ROMK) in an inhibitory manner to maintain normokalaemia and normotension.	Potassium	269-278	cullin 3	Homo sapiens	38-46
31801305-2	2019	We recently devised a model of large-conductance BKCa potassium currents, and hence BKCa-CaV complexes controlled locally by CaVs via Ca2+ nanodomains.	Potassium	54-63	caveolin 2	Homo sapiens	89-92
31795491-3	2019	The encoded proteins Kelch-like 3 and Cullin 3 interact to form a ring-like complex to ubiquitinate WNK-kinase 4, which, in normal circumstances, interacts with the sodium chloride co-symporter (NCC), the epithelial sodium channel (ENaC), and the renal outer medullary potassium channel (ROMK) in an inhibitory manner to maintain normokalaemia and normotension.	Potassium	269-278	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	288-292
31657415-1	2019	The indyl anion, K[In(NONDipp)] (NONDipp = [O(SiMe2NDipp)2]2-, Dipp = 2,6-iPr2C6H3) reacts with group 12 compounds M(BDIR)Cl (M = Zn, Cd; BDI = [HC{C(Me)NR}2]-, R = 2,4,6-Me3C6H2 (Mes), Dipp) to afford the heterobimetallic compounds (NONDipp)In-M(BDIR) that contain the first In-Zn and In-Cd bonds.	Potassium	17-31	nudix hydrolase 3	Homo sapiens	36-40
31849684-10	2019	These results suggest that activation of alpha7nAChR with anisodamine could decrease serum potassium and on-site mortality in CS through estradiol-induced enhancement of insulin sensitivity.	Potassium	91-100	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	41-52
31827438-2	2019	We explored if blocking the background and the acetylcholine-activated inward rectifier potassium currents (IK1 and IKACh) could be antiarrhythmic in persistent atrial fibrillation.	Potassium	88-97	IKAROS family zinc finger 1	Homo sapiens	108-111
31819513-0	2019	The Long Non-Coding RNA-14327.1 Promotes Migration and Invasion Potential of Endometrial Carcinoma Cells by Stabilizing the Potassium Channel Kca3.1.	Potassium	124-133	potassium calcium-activated channel subfamily N member 4	Homo sapiens	142-148
31628184-11	2019	These observations support the hypothesis that PSPs in arcuate kisspeptin neurons are regulated by estradiol-sensitive mechanisms including potassium conductances and membrane properties.SIGNIFICANCE STATEMENT Kisspeptin neurons relay estradiol feedback to gonadotropin-releasing hormone neurons, which regulate the reproductive system.	Potassium	140-149	KiSS-1 metastasis-suppressor	Mus musculus	63-73
31628184-11	2019	These observations support the hypothesis that PSPs in arcuate kisspeptin neurons are regulated by estradiol-sensitive mechanisms including potassium conductances and membrane properties.SIGNIFICANCE STATEMENT Kisspeptin neurons relay estradiol feedback to gonadotropin-releasing hormone neurons, which regulate the reproductive system.	Potassium	140-149	KiSS-1 metastasis-suppressor	Mus musculus	210-220
31819513-1	2019	Background: The intermediate-conductance Ca2+-activated potassium channel (Kca3.1) plays a key role in maintaining intracellular Ca2+ homeostasis and is involved with the carcinogenesis of many human tumors including endometrial carcinoma.	Potassium	56-65	potassium calcium-activated channel subfamily N member 4	Homo sapiens	75-81
31771312-1	2019	TWIK-related potassium channel-1 (TREK-1) is broadly expressed in the brain and involved in diverse brain diseases, such as seizures, ischemia, and depression.	Potassium	13-22	potassium channel, subfamily K, member 2	Mus musculus	34-40
31771292-3	2019	This study examined the effectiveness of RIPC in a mouse model of hepatic IR and aimed to clarify the mechanism and relationship of the ATP-sensitive potassium channel (KATP) and HMGB1-induced TLR4/MyD88/NF-kappaB signaling.	Potassium	150-159	high mobility group box 1	Mus musculus	179-184
31768497-8	2019	Single guide RNAs expressed from the duplicated promoter mediated edits in the N. benthamiana Phytoene desaturase gene, the S. viridis Carbonic anhydrase 2 gene, and the maize HKT1 gene encoding a potassium transporter.	Potassium	197-206	Cation transporter HKT8-like	Zea mays	176-180
31771292-3	2019	This study examined the effectiveness of RIPC in a mouse model of hepatic IR and aimed to clarify the mechanism and relationship of the ATP-sensitive potassium channel (KATP) and HMGB1-induced TLR4/MyD88/NF-kappaB signaling.	Potassium	150-159	toll-like receptor 4	Mus musculus	193-197
31771292-3	2019	This study examined the effectiveness of RIPC in a mouse model of hepatic IR and aimed to clarify the mechanism and relationship of the ATP-sensitive potassium channel (KATP) and HMGB1-induced TLR4/MyD88/NF-kappaB signaling.	Potassium	150-159	myeloid differentiation primary response gene 88	Mus musculus	198-203
31771292-3	2019	This study examined the effectiveness of RIPC in a mouse model of hepatic IR and aimed to clarify the mechanism and relationship of the ATP-sensitive potassium channel (KATP) and HMGB1-induced TLR4/MyD88/NF-kappaB signaling.	Potassium	150-159	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	204-213
31594866-1	2019	The association of plasma membrane (PM)-localized voltage-gated potassium (Kv2) channels with endoplasmic reticulum (ER)-localized vesicle-associated membrane protein-associated proteins VAPA and VAPB defines ER-PM junctions in mammalian brain neurons.	Potassium	64-73	VAMP associated protein A	Homo sapiens	187-191
31594866-1	2019	The association of plasma membrane (PM)-localized voltage-gated potassium (Kv2) channels with endoplasmic reticulum (ER)-localized vesicle-associated membrane protein-associated proteins VAPA and VAPB defines ER-PM junctions in mammalian brain neurons.	Potassium	64-73	VAMP associated protein B and C	Homo sapiens	196-200
31472317-5	2019	As a result, the electrochemical properties of the potassium ion battery are enhanced when an AC@CoP/NCNTs/CNFs nanocomposite is used as the anode electrode, and the electrode exhibits a reversible capacity of 247 mA h g-1 after 1000 cycles at 0.8 A g-1 in a potassium ion battery.	Potassium	51-60	caspase recruitment domain family member 16	Homo sapiens	97-100
31472317-5	2019	As a result, the electrochemical properties of the potassium ion battery are enhanced when an AC@CoP/NCNTs/CNFs nanocomposite is used as the anode electrode, and the electrode exhibits a reversible capacity of 247 mA h g-1 after 1000 cycles at 0.8 A g-1 in a potassium ion battery.	Potassium	259-268	caspase recruitment domain family member 16	Homo sapiens	97-100
31787993-6	2019	Key Results: 10 muM AVG treatment increases K15NO3 uptake and 15N translocation during root growth inhibition whereas 10 muM AVG + 1 mM 15Nglutamate treatment inhibits K15NO3 uptake and increases 15Nglutamate uptake during partial root growth restoration.	Potassium	44-50	latexin	Homo sapiens	16-19
31803246-12	2019	These suggest that KCNQ1 and SCN2A, genes that encode potassium and sodium channels, respectively, may serve as putative diagnostic targets for the diagnosis and prognosis of PHEO and therefore facilitate the clinical management of PHEO.	Potassium	54-63	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	19-24
31803246-12	2019	These suggest that KCNQ1 and SCN2A, genes that encode potassium and sodium channels, respectively, may serve as putative diagnostic targets for the diagnosis and prognosis of PHEO and therefore facilitate the clinical management of PHEO.	Potassium	54-63	sodium voltage-gated channel alpha subunit 2	Homo sapiens	29-34
31803058-2	2019	SA4503, known as a sigma1 receptor agonist, regulates cardiac calcium and potassium channels in rat models of depression.	Potassium	74-83	sigma non-opioid intracellular receptor 1	Rattus norvegicus	19-34
31787993-6	2019	Key Results: 10 muM AVG treatment increases K15NO3 uptake and 15N translocation during root growth inhibition whereas 10 muM AVG + 1 mM 15Nglutamate treatment inhibits K15NO3 uptake and increases 15Nglutamate uptake during partial root growth restoration.	Potassium	168-174	latexin	Homo sapiens	121-124
31706919-0	2021	The role of P-glycoprotein (P-gp) and inwardly rectifying potassium (Kir) channels in sudden unexpected death in epilepsy (SUDEP).	Potassium	58-67	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	69-72
31780884-3	2019	To date, and directly relevant to the present review, sigma1R has been found to regulate both voltage-gated ion channels (VGICs) belonging to distinct superfamilies (i.e., sodium, Na+; potassium, K+; and calcium, Ca2+ channels) and non-voltage-gated ion channels.	Potassium	185-194	sigma non-opioid intracellular receptor 1	Homo sapiens	54-61
31807018-0	2019	The hERG1 Potassium Channel Behaves As Prognostic Factor In Gastric Dysplasia Endoscopic Samples.	Potassium	10-19	potassium voltage-gated channel subfamily H member 2	Homo sapiens	4-9
31706919-5	2021	Other molecular regulators of membrane potential are the inwardly rectifying potassium channels (Kir), whose genetic variants have been related to both epilepsy and heart dysfunctions.	Potassium	77-86	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	97-100
31657282-4	2019	The aim of this study is to estimate the longitudinal association between hypertension diagnosis and subsequent changes (within 2-4 years) in dietary sodium, potassium, and sodium-potassium (Na/K) ratio.	Potassium	180-189	TANK binding kinase 1	Homo sapiens	191-195
31685809-8	2019	In order to better characterize the physiologic role and modulation mechanisms of KCASH2, we have searched through a proteomic approach for new KCASH2 interactors, identifying Potassium Channel Tetramerization Domain Containing 15 (KCTD15).	Potassium	176-185	potassium channel tetramerization domain containing 21	Homo sapiens	82-88
31695023-4	2019	Studies conducted in the last eight years have identified somatic driver mutations in a substantial portion of aldosterone-producing adenomas, including the genes KCNJ5 (encoding inwardly rectifying potassium channel GIRK4), CACNA1D (encoding a subunit of L-type voltage-gated calcium channel CaV1.3), ATP1A1 (encoding a subunit of Na+/K+-ATPase), ATP2B3 (encoding a Ca2+-ATPase), and CTNNB1 (encoding ss-catenin).	Potassium	199-208	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	163-168
31162688-4	2019	Here, we review the evidence of PACAP-dependent modulation of calcium- and voltage-gated potassium currents, hyperpolarization-activated cation currents, calcium currents, and voltage-gated sodium currents.	Potassium	89-98	adenylate cyclase activating polypeptide 1	Homo sapiens	32-37
31669719-2	2019	KV1.3 ion channel is a voltage-gated potassium channel and has been validated as a drug target for autoimmune and chronic inflammatory diseases like psoriasis.	Potassium	37-46	potassium voltage-gated channel subfamily A member 3	Homo sapiens	0-5
31731488-1	2019	The ubiquitously expressed family of inward rectifier potassium (KIR) channels, encoded by KCNJ genes, is primarily involved in cell excitability and potassium homeostasis.	Potassium	54-63	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	65-68
31731488-1	2019	The ubiquitously expressed family of inward rectifier potassium (KIR) channels, encoded by KCNJ genes, is primarily involved in cell excitability and potassium homeostasis.	Potassium	150-159	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	65-68
31649201-4	2019	The structural and functional analyses, along with computational studies, reveal one potassium site and two chloride sites in KCC1, which are all required for the ion transport activity.	Potassium	85-94	solute carrier family 12 member 4	Homo sapiens	126-130
31772770-0	2019	GLP-1 Relaxes Rat Coronary Arteries by Enhancing ATP-Sensitive Potassium Channel Currents.	Potassium	63-72	glucagon	Rattus norvegicus	0-5
31640787-1	2019	BACKGROUND: Dysfunction in inwardly rectifying potassium channel Kir4.1 has been implicated in SeSAME syndrome, an autosomal-recessive (AR), rare, multi-systemic disorder.	Potassium	47-56	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	65-71
31635148-0	2019	N-Glycosylation of TREK-1/hK2P2.1 Two-Pore-Domain Potassium (K2P) Channels.	Potassium	50-59	potassium two pore domain channel subfamily K member 2	Homo sapiens	19-25
31635148-1	2019	Mechanosensitive hTREK-1 two-pore-domain potassium (hK2P2.1) channels give rise to background currents that control cellular excitability.	Potassium	41-50	potassium two pore domain channel subfamily K member 2	Homo sapiens	17-24
31635148-9	2019	Detection of glycosylation-deficient mutant channels in surface fractions and recordings of macroscopic potassium currents mediated by these subunits demonstrated that nonglycosylated hTREK-1 channel subunits are able to reach the cell surface in general but with seemingly reduced efficiency compared to glycosylated subunits.	Potassium	104-113	potassium two pore domain channel subfamily K member 2	Homo sapiens	184-191
31623161-8	2019	We show that normal functioning of ClC-7 supports the acidification process, is associated with increased luminal concentrations of sodium, potassium, and chloride, and leads to a higher Ca2+ uptake and release.	Potassium	140-149	chloride voltage-gated channel 7	Homo sapiens	35-40
31680980-0	2019	Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats.	Potassium	0-9	renin	Rattus norvegicus	47-52
31680980-0	2019	Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats.	Potassium	0-9	angiotensin I converting enzyme 2	Rattus norvegicus	96-100
31680980-0	2019	Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats.	Potassium	0-9	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	105-110
31680980-0	2019	Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats.	Potassium	0-9	angiotensinogen	Rattus norvegicus	129-143
31570602-2	2019	Here, we discovered that hypotensive folk medicines from a genetically diverse range of plant species each selectively activated the vascular-expressed KCNQ5 potassium channel, a feature lacking in the modern synthetic pharmacopeia, whereas nonhypotensive plant extracts did not.	Potassium	158-167	potassium voltage-gated channel subfamily Q member 5	Homo sapiens	152-157
31570602-5	2019	Discovery of botanical KCNQ5-selective potassium channel openers may enable future targeted therapies for diseases including hypertension and KCNQ5 loss-of-function encephalopathy.	Potassium	39-48	potassium voltage-gated channel subfamily Q member 5	Homo sapiens	23-28
31570602-5	2019	Discovery of botanical KCNQ5-selective potassium channel openers may enable future targeted therapies for diseases including hypertension and KCNQ5 loss-of-function encephalopathy.	Potassium	39-48	potassium voltage-gated channel subfamily Q member 5	Homo sapiens	142-147
31553596-2	2019	Here, a simple strategy of partial congener substitution is introduced to induce transformation of the known centrosymmetric K3Ga3Ge7Se20 (P21/c) to the new isostructural NCS species K3Ga3(Ge6.17Sn0.83)Se20 (1) and K3Ga3(Ge4.95Si2.05)Se20 (2) (Pc).	Potassium	125-130	H3 histone pseudogene 16	Homo sapiens	139-144
31553596-2	2019	Here, a simple strategy of partial congener substitution is introduced to induce transformation of the known centrosymmetric K3Ga3Ge7Se20 (P21/c) to the new isostructural NCS species K3Ga3(Ge6.17Sn0.83)Se20 (1) and K3Ga3(Ge4.95Si2.05)Se20 (2) (Pc).	Potassium	183-188	H3 histone pseudogene 16	Homo sapiens	139-144
30446179-8	2019	Alterations in metabolic pathways associated with the sensitivity of sodium, potassium, magnesium and calcium may lead to obesity, hypertension, and insulin resistance.	Potassium	77-86	insulin	Homo sapiens	149-156
31038230-3	2019	Recently, we reported on hypoexcitability and increased cell death in a FUS/SOD1-ALS-induced pluripotent stem cell-derived motor neuron model, which was partly reversible by a treatment with the potassium channel blocker 4-aminopyridine (4-AP).	Potassium	195-204	FUS RNA binding protein	Homo sapiens	72-75
31038230-3	2019	Recently, we reported on hypoexcitability and increased cell death in a FUS/SOD1-ALS-induced pluripotent stem cell-derived motor neuron model, which was partly reversible by a treatment with the potassium channel blocker 4-aminopyridine (4-AP).	Potassium	195-204	superoxide dismutase 1	Homo sapiens	76-80
31212067-2	2019	One example of such a channelopathy is the reduction of A-type potassium currents in the hippocampal CA1 region.	Potassium	63-72	carbonic anhydrase 1	Mus musculus	101-104
31212067-4	2019	Here, we show that inhibiting a single microRNA, miR-324-5p, which targets the pore-forming A-type potassium channel subunit Kv4.2, selectively increased A-type potassium currents in hippocampal CA1 pyramidal neurons in mice.	Potassium	99-108	microRNA 324	Mus musculus	49-56
31212067-4	2019	Here, we show that inhibiting a single microRNA, miR-324-5p, which targets the pore-forming A-type potassium channel subunit Kv4.2, selectively increased A-type potassium currents in hippocampal CA1 pyramidal neurons in mice.	Potassium	99-108	potassium voltage-gated channel, Shal-related family, member 2	Mus musculus	125-130
31212067-4	2019	Here, we show that inhibiting a single microRNA, miR-324-5p, which targets the pore-forming A-type potassium channel subunit Kv4.2, selectively increased A-type potassium currents in hippocampal CA1 pyramidal neurons in mice.	Potassium	99-108	carbonic anhydrase 1	Mus musculus	195-198
31511966-1	2019	The TWIK-related K+ channel (TREK-1) is a two-pore-domain potassium channel that produces background leaky potassium currents.	Potassium	58-67	potassium channel, subfamily K, member 2	Mus musculus	29-35
31612103-0	2019	Voltage-Gated Potassium Channel Kv1.3 as a Target in Therapy of Cancer.	Potassium	14-23	potassium voltage-gated channel subfamily A member 3	Homo sapiens	32-37
31612103-1	2019	Voltage-gated potassium channel Kv1.3 is an integral membrane protein, which is selectively permeable for potassium ions and is activated upon a change of membrane potential.	Potassium	14-23	potassium voltage-gated channel subfamily A member 3	Homo sapiens	32-37
31612103-1	2019	Voltage-gated potassium channel Kv1.3 is an integral membrane protein, which is selectively permeable for potassium ions and is activated upon a change of membrane potential.	Potassium	106-115	potassium voltage-gated channel subfamily A member 3	Homo sapiens	32-37
31616316-8	2019	Among 19 commonly affected genes in comparison with human AF, downregulation of FOXP1 and upregulation of the KCNK2 gene encoding the Kir2.1 potassium channel were conspicuous findings, suggesting NFAT activation.	Potassium	141-150	potassium two pore domain channel subfamily K member 2	Homo sapiens	110-115
31616316-8	2019	Among 19 commonly affected genes in comparison with human AF, downregulation of FOXP1 and upregulation of the KCNK2 gene encoding the Kir2.1 potassium channel were conspicuous findings, suggesting NFAT activation.	Potassium	141-150	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	134-140
31616316-8	2019	Among 19 commonly affected genes in comparison with human AF, downregulation of FOXP1 and upregulation of the KCNK2 gene encoding the Kir2.1 potassium channel were conspicuous findings, suggesting NFAT activation.	Potassium	141-150	nuclear factor of activated T-cells 5	Rattus norvegicus	197-201
31342621-0	2019	High-Throughput Production of Zr-Doped Li4 Ti5 O12 Modified by Mesoporous Libaf3 Nanoparticles for Superior Lithium and Potassium Storage.	Potassium	120-129	lipase family member N	Homo sapiens	39-42
31486928-3	2019	The transmembrane water channel AQP1 is important for cardiorespiratory endurance (CE) because it influences fluid transfers in erythrocytes, endothelial, and pulmonary cells and is vital for transport of ammonium, bicarbonate, carbon dioxide, glycerol, nitric oxide, potassium ion, water, and trans-epithelial and renal water.	Potassium	268-277	aquaporin 1	Mus musculus	32-36
31172810-9	2019	Nicotine induced premature hypertension, renal expression of the sodium-potassium chloride cotransporter (NKCC2), increases in renal sodium retention, and infiltration of CD161a+/CD68+ macrophages into the renal medulla.	Potassium	72-81	solute carrier family 12 member 1	Rattus norvegicus	106-111
31136755-0	2019	Erv14 cargo receptor participates in regulation of plasma-membrane potential, intracellular pH and potassium homeostasis via its interaction with K+-specific transporters Trk1 and Tok1.	Potassium	99-108	Trk1p	Saccharomyces cerevisiae S288C	171-175
31136755-0	2019	Erv14 cargo receptor participates in regulation of plasma-membrane potential, intracellular pH and potassium homeostasis via its interaction with K+-specific transporters Trk1 and Tok1.	Potassium	99-108	Tok1p	Saccharomyces cerevisiae S288C	180-184
31498767-0	2019	ACE inhibitors and ARBs: Managing potassium and renal function.	Potassium	34-43	angiotensin I converting enzyme	Homo sapiens	0-3
31374572-5	2019	Increased catalase activities, NADH/NAD+ ratio and contents of several metals, especially potassium, were observed by YCR102C overexpression under acetic acid stress.	Potassium	90-99	uncharacterized protein	Saccharomyces cerevisiae S288C	118-125
31700971-5	2019	The potassium level has dropped gradually to a normal level with continuous insulin infusion and dextrose for almost 12 hours that waved the need of the dialysis.	Potassium	4-13	insulin	Homo sapiens	76-83
31624723-11	2019	The relative abundance of beta-glucuronidase (K01195) was higher in female IL-10 KO mice than that in female WT mice by PICRUSt.	Potassium	46-52	glucuronidase, beta	Mus musculus	26-44
31624723-11	2019	The relative abundance of beta-glucuronidase (K01195) was higher in female IL-10 KO mice than that in female WT mice by PICRUSt.	Potassium	46-52	interleukin 10	Mus musculus	75-80
31446696-13	2019	KMT2D and KDM6A are two pathogenic genes that have been identified for KS.	Potassium	71-73	lysine methyltransferase 2D	Homo sapiens	0-5
31446696-13	2019	KMT2D and KDM6A are two pathogenic genes that have been identified for KS.	Potassium	71-73	lysine demethylase 6A	Homo sapiens	10-15
30901316-1	2019	Hypokalemic periodic paralysis (HOKPP) is a rare neuromuscular disorder caused by altered transport of cellular potassium that leads to significant muscle weakness of the extremities.	Potassium	112-121	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	32-37
31461851-1	2019	The subunits KCNQ1 and KCNE1 generate the slowly activating, delayed rectifier potassium current, IKs, that responds to sympathetic stimulation and is critical for human cardiac repolarization.	Potassium	79-88	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	13-18
31461851-1	2019	The subunits KCNQ1 and KCNE1 generate the slowly activating, delayed rectifier potassium current, IKs, that responds to sympathetic stimulation and is critical for human cardiac repolarization.	Potassium	79-88	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	23-28
31434872-2	2019	Most KCNQ4 mutations linked to hearing loss are clustered around the pore region of the protein and lead to loss of KCNQ4-mediated potassium currents.	Potassium	131-140	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	5-10
31434872-2	2019	Most KCNQ4 mutations linked to hearing loss are clustered around the pore region of the protein and lead to loss of KCNQ4-mediated potassium currents.	Potassium	131-140	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	116-121
31253715-5	2019	Specifically, targeted RNAi knock-down of either Para fast voltage-gated sodium, Shaker potassium (Kv1 homologue), or surprisingly, L-type like calcium channels counteracts postnatal increases in GF axonal conduction velocity.	Potassium	88-97	Shaker	Drosophila melanogaster	99-102
31053371-5	2019	After treatment with an injection of calcium gluconate, insulin with glucose, bicarbonate, and an enema with polystyrene sulfonate, the patient"s serum potassium level normalized and the bradyarrhythmia converted to a normal sinus rhythm.	Potassium	152-161	insulin	Homo sapiens	56-63
31241995-4	2019	Cellular expression of two APOL1 RRVs has been demonstrated to induce cytotoxicity, including necrosis, apoptosis, and pyroptosis in several cell types including podocytes; mechanistically, these toxicities were attributed to lysosomal swelling, potassium-depletion, mitochondrial dysfunction, autophagy blockade, PKR activation, UBD degradation, and ER stress; notably, these effects were found to be dose-dependent and occurred only in overtly APOL1 RRVs-expressing cells.	Potassium	246-255	apolipoprotein L1	Homo sapiens	27-32
31303267-4	2019	PCP-administered GLAST wild-type (+/+) mice showed enhancement of immobility in a forced swimming test, impairments of visual recognition memory in a novel object recognition test, decrease in high potassium (K+)-induced extracellular glutamate release, and overexpression of GLAST and S100 proteins in the PFC, compared to saline-administered GLAST+/+ mice.	Potassium	198-207	solute carrier family 1 (glial high affinity glutamate transporter), member 3	Mus musculus	17-22
31239388-2	2019	The role of Kir5.1 (encoded by Kcnj16) in mediating effects of dietary potassium intake on the NCC and renal potassium excretion is unknown.	Potassium	71-80	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	31-37
31239388-5	2019	Compared with wild-type, Kcnj16-/- mice fed a normal potassium diet had higher basolateral potassium conductance, a more negative DCT membrane potential, higher expression of phosphorylated NCC (pNCC) and total NCC (tNCC), and augmented thiazide-induced natriuresis.	Potassium	53-62	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	25-31
31239388-5	2019	Compared with wild-type, Kcnj16-/- mice fed a normal potassium diet had higher basolateral potassium conductance, a more negative DCT membrane potential, higher expression of phosphorylated NCC (pNCC) and total NCC (tNCC), and augmented thiazide-induced natriuresis.	Potassium	91-100	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	25-31
31239388-9	2019	Compared with wild-type, Kcnj16-/- mice with normal potassium intake had slightly lower plasma potassium but were more hyperkalemic with prolonged high potassium intake and more hypokalemic during potassium restriction.	Potassium	52-61	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	25-31
31239388-9	2019	Compared with wild-type, Kcnj16-/- mice with normal potassium intake had slightly lower plasma potassium but were more hyperkalemic with prolonged high potassium intake and more hypokalemic during potassium restriction.	Potassium	95-104	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	25-31
31239388-9	2019	Compared with wild-type, Kcnj16-/- mice with normal potassium intake had slightly lower plasma potassium but were more hyperkalemic with prolonged high potassium intake and more hypokalemic during potassium restriction.	Potassium	95-104	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	25-31
31239388-9	2019	Compared with wild-type, Kcnj16-/- mice with normal potassium intake had slightly lower plasma potassium but were more hyperkalemic with prolonged high potassium intake and more hypokalemic during potassium restriction.	Potassium	95-104	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	25-31
31239388-10	2019	CONCLUSIONS: Kir5.1 is essential for dietary potassium"s effect on NCC and for maintaining potassium homeostasis.	Potassium	45-54	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	13-19
31239388-10	2019	CONCLUSIONS: Kir5.1 is essential for dietary potassium"s effect on NCC and for maintaining potassium homeostasis.	Potassium	91-100	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	13-19
31466741-0	2019	Effect of heat stress and Hsp90 inhibition on T-type calcium currents and voltage-dependent potassium currents in leydig cells.	Potassium	92-101	heat shock protein 86, pseudogene 1	Mus musculus	26-31
30849204-9	2019	The kr and Ks values were 0.027 mg L-1  min-1  and 0.621 L/mg, respectively.	Potassium	11-13	L1 cell adhesion molecule	Homo sapiens	35-45
31357463-5	2019	The results of modelling showed that mumax = 0.179 1/h and Ks = 11.37 g.L-1 for the Monod model, whereas mumax = 0.508 1/h, Ks = 47.53 g.L-1 and Ki = 181.01 g.L-1 for the Andrews model, which are too close to the values reported in previous studies.	Potassium	59-61	immunoglobulin kappa variable 1-16	Homo sapiens	72-75
31346773-3	2019	We show in this work that the activity of this transporter is regulated at the posttranslational level, and thus Trk1 contributes to potassium uptake under very different external cation concentrations.	Potassium	133-142	Trk1p	Saccharomyces cerevisiae S288C	113-117
31145900-3	2019	For example, NKCC2 resorbs chloride with sodium and potassium ions at the apical membrane of epithelial cells in the kidney, whereas KCC3 releases chloride with potassium ions at the basolateral membrane.	Potassium	52-61	solute carrier family 12 member 1	Homo sapiens	13-18
31145900-3	2019	For example, NKCC2 resorbs chloride with sodium and potassium ions at the apical membrane of epithelial cells in the kidney, whereas KCC3 releases chloride with potassium ions at the basolateral membrane.	Potassium	161-170	solute carrier family 12 member 6	Homo sapiens	133-137
31636949-4	2019	Through systematic profiling studies, we show that human SIRT3 displays class-selective histone de-beta-hydroxybutyrylase activities with preference for H3 K4, K9, K18, K23, K27, and H4K16, but not for H4 K5, K8, K12, which distinguishes it from the Zn-dependent HDACs.	Potassium	205-207	sirtuin 3	Homo sapiens	57-62
31283756-5	2019	Applied to data from two FDA funded studies (22+22 subjects, 5232+4208 ECGs) which target ECG effects of various ion-channel blocking drugs, the TrX effect profiles indicate increasingly delayed electrical activity over the entire repolarization process for drugs solely reducing outward potassium current (dofetilide, moxifloxacin).	Potassium	288-297	thioredoxin	Homo sapiens	145-148
30865168-9	2019	SUMMARY: Chloride sensing by WNK kinase provides a mechanism to allow coupling of extracellular potassium with NCC phosphorylation and activity to maintain potassium homeostasis.	Potassium	96-105	Wnk kinase	Drosophila melanogaster	29-32
30865168-9	2019	SUMMARY: Chloride sensing by WNK kinase provides a mechanism to allow coupling of extracellular potassium with NCC phosphorylation and activity to maintain potassium homeostasis.	Potassium	156-165	Wnk kinase	Drosophila melanogaster	29-32
30883902-2	2019	Vascular endothelial growth factor (VEGF), an original biological substance of vessels, regulates the movement of calcium and potassium ions across neuronal membrane.	Potassium	126-135	vascular endothelial growth factor A	Homo sapiens	0-34
30883902-2	2019	Vascular endothelial growth factor (VEGF), an original biological substance of vessels, regulates the movement of calcium and potassium ions across neuronal membrane.	Potassium	126-135	vascular endothelial growth factor A	Homo sapiens	36-40
30997950-0	2019	Surface-Confined SnS2 @C@rGO as High-Performance Anode Materials for Sodium- and Potassium-Ion Batteries.	Potassium	81-90	sodium voltage-gated channel alpha subunit 11	Homo sapiens	17-21
30965109-0	2019	ADAM23 is a negative regulator of Kv1.1/Kv1.4 potassium currents.	Potassium	46-55	ADAM metallopeptidase domain 23	Homo sapiens	0-6
30965109-0	2019	ADAM23 is a negative regulator of Kv1.1/Kv1.4 potassium currents.	Potassium	46-55	potassium voltage-gated channel subfamily A member 1	Homo sapiens	34-39
30965109-0	2019	ADAM23 is a negative regulator of Kv1.1/Kv1.4 potassium currents.	Potassium	46-55	potassium voltage-gated channel subfamily A member 4	Homo sapiens	40-45
30965109-7	2019	Results Cells transfected with Kv1.1/Kv1.4 showed voltage-gated potassium currents (Kv1.1 currents).	Potassium	64-73	potassium voltage-gated channel subfamily A member 1	Homo sapiens	31-36
30965109-7	2019	Results Cells transfected with Kv1.1/Kv1.4 showed voltage-gated potassium currents (Kv1.1 currents).	Potassium	64-73	potassium voltage-gated channel subfamily A member 4	Homo sapiens	37-42
30965109-7	2019	Results Cells transfected with Kv1.1/Kv1.4 showed voltage-gated potassium currents (Kv1.1 currents).	Potassium	64-73	potassium voltage-gated channel subfamily A member 1	Homo sapiens	84-89
30971438-3	2019	[ahx5-24]NPY also reduced tonic activation of GABAB receptors (GABABR), which increased PN excitability through inhibition of a tonic, inwardly rectifying potassium current (KIR ).	Potassium	155-164	neuropeptide Y	Rattus norvegicus	9-12
30936239-14	2019	Treatment with a drug that alters the voltage dependence of Kv3.1 channels normalizes the imbalance of potassium currents, as well as ABR responses in vivo, suggesting that such compounds may be effective in treating some symptoms of fragile X syndrome.	Potassium	103-112	potassium voltage gated channel, Shaw-related subfamily, member 1	Mus musculus	60-65
30831494-0	2019	Fenton-like and potassium permanganate oxidations of PAH-contaminated soils: Impact of oxidant doses on PAH and polar PAC (polycyclic aromatic compound) behavior.	Potassium	16-25	phenylalanine hydroxylase	Homo sapiens	53-56
29761317-7	2019	Compared with Na:Ks less than 1.0, the levels of both baPWV and cIMT were higher for participants with Na:Ks over 1.0 (baPWV: p for trend = 0.0002 for Na:Kaverage; cIMT: p for trend = 0.005 for Na:Kaverage).	Potassium	106-108	CIMT	Homo sapiens	64-68
31053903-0	2019	Potassium Stimulation of IAA Transport Mediated by the Arabidopsis Importer AUX1 Investigated in a Heterologous Yeast System.	Potassium	0-9	Transmembrane amino acid transporter family protein	Arabidopsis thaliana	76-80
30849538-14	2019	Analysis of the Ka/Ks ratios of Cardamineae suggested positive selection exerted on the ycf2 gene in watercress, which might reflect specific adaptations of watercress to its particular living environment.	Potassium	19-21	ycf2	Nasturtium officinale	88-92
31178727-0	2019	Ultrasound Stimulation Modulates Voltage-Gated Potassium Currents Associated With Action Potential Shape in Hippocampal CA1 Pyramidal Neurons.	Potassium	47-56	carbonic anhydrase 1	Homo sapiens	120-123
31113422-8	2019	The detrusor strips from TREK-1 KO mice also generated more contractile force in response to electric field stimulation and high potassium concentration in comparison to WT group (p &lt;= 0.05 for both tests).	Potassium	129-138	potassium channel, subfamily K, member 2	Mus musculus	25-31
30812034-2	2019	We tested the hypothesis of an association between the prevalence of the genotypic and allelic frequencies distribution of the potassium voltage-gated channel of the shaker related subfamily member 4 gene (KCNA4) rs1323860 (C/T transition) and endurance performance level in Hispanic male marathon runners (MR).	Potassium	127-136	potassium voltage-gated channel subfamily A member 4	Homo sapiens	206-211
31024004-0	2019	RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux.	Potassium	95-104	NLR family pyrin domain containing 3	Homo sapiens	38-43
31024004-4	2019	Here, we report that the replication of cytopathogenic RNA viruses such as vesicular stomatitis virus (VSV) or encephalomyocarditis virus (EMCV) induced a lytic cell death leading to potassium efflux, the common trigger of NLRP3 inflammasome activation.	Potassium	183-192	NLR family pyrin domain containing 3	Homo sapiens	223-228
31044010-0	2019	Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance.	Potassium	78-87	Trk1p	Saccharomyces cerevisiae S288C	63-67
31044010-6	2019	Potassium supplementation growth assays showed that mutated TRK1 alleles and extracellular potassium supplementation not only conferred tolerance to PA stress but also to multiple organic acids.	Potassium	0-9	Trk1p	Saccharomyces cerevisiae S288C	60-64
31001573-4	2019	Given insulin to these patients immediately can lead to further decrease in extracellular potassium level and lead to cardiac dysrhythmias and death.	Potassium	90-99	insulin	Homo sapiens	6-13
31093276-6	2019	In both the SPC and SPPoC groups, there was a decrease in the ALT level and an increase in the bicarbonate and potassium serum levels.	Potassium	111-120	surfactant protein C	Rattus norvegicus	12-15
31043849-4	2019	Ka/Ks ratios analyses of protein-coding genes revealed that the highest and lowest rates were found in ND6 and COI and that all these genes were evolving under purifying selection.	Potassium	3-5	mitochondrially encoded NADH dehydrogenase 6	Homo sapiens	103-106
29968124-6	2019	Potassium was significantly higher in milk from Nitra region (3301.98 +- 95.66) against SK sample (2925.16 +- 75.74 mug/mL).	Potassium	0-9	Weaning weight-maternal milk	Bos taurus	38-42
30792104-2	2019	Additionally, inhibition of potassium current through the cardiac hERG channel by bedaquiline, is associated with prolongation of the QT interval, necessitating cardiovascular monitoring.	Potassium	28-37	ETS transcription factor ERG	Homo sapiens	66-70
30888091-2	2019	Furthermore, SIMesPK was used in reactions with potassium amides and alkoxides to form the molecular phosphorus-potassium clusters [K4 (SIMesP)2 (hmds)2 ] [5, hmds=N(SiMe3 )2 ] and [K6 (SIMesP)2 (OtBu)4 ] (6).	Potassium	48-57	keratin 4	Homo sapiens	132-144
30659840-0	2019	cAMP-producing chemogenetic and adenosine A2a receptor activation inhibits the inwardly rectifying potassium current in striatal projection neurons.	Potassium	99-108	adenosine A2a receptor	Homo sapiens	32-54
30909873-9	2019	In multivariable linear regression analysis, the urinary AGT/creatinine (Cr) ratio was negatively correlated with the serum potassium level (beta = - 0.058, P = 0.017) and positively correlated with the transtubular potassium gradient (TTKG, beta = 0.087, P = 0.001).	Potassium	124-133	angiotensinogen	Homo sapiens	57-60
30909873-9	2019	In multivariable linear regression analysis, the urinary AGT/creatinine (Cr) ratio was negatively correlated with the serum potassium level (beta = - 0.058, P = 0.017) and positively correlated with the transtubular potassium gradient (TTKG, beta = 0.087, P = 0.001).	Potassium	216-225	angiotensinogen	Homo sapiens	57-60
30967788-2	2019	LQT1 is a subtype of LQTS caused by mutations in KCNQ1, affecting the slow delayed-rectifier potassium current (I Ks), which is essential for cardiac repolarization.	Potassium	93-102	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-4
30967788-2	2019	LQT1 is a subtype of LQTS caused by mutations in KCNQ1, affecting the slow delayed-rectifier potassium current (I Ks), which is essential for cardiac repolarization.	Potassium	93-102	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	49-54
30967788-2	2019	LQT1 is a subtype of LQTS caused by mutations in KCNQ1, affecting the slow delayed-rectifier potassium current (I Ks), which is essential for cardiac repolarization.	Potassium	114-116	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-4
30967788-2	2019	LQT1 is a subtype of LQTS caused by mutations in KCNQ1, affecting the slow delayed-rectifier potassium current (I Ks), which is essential for cardiac repolarization.	Potassium	114-116	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	49-54
30765526-10	2019	The results provide compelling support for the notion that WNK4 is a bona fide physiological intracellular Cl- sensor and that Cl- regulation of WNK4 underlies the mechanism of regulation of NCC by extracellular potassium.	Potassium	212-221	WNK lysine deficient protein kinase 4	Mus musculus	145-149
29976269-3	2019	The milk concentration of calcium (Ca), potassium (K), magnesium (Mg), sodium (Na) and phosphorus (P) in the present study was quantified from mid-IR spectroscopy on 12 223 test-day records from 1717 Holstein-Friesian cows.	Potassium	40-49	Weaning weight-maternal milk	Bos taurus	4-8
32626251-1	2019	In this opinion, the EFSA Panel on Food Additives and Flavourings (FAF Panel) was requested by the European Commission to carry out a scientific evaluation of an extended one-generation reproductive toxicity study (EOGRTS) to determine whether it would allow reconsideration of the temporary group acceptable daily intake (ADI) for sorbic acid (E 200) and potassium sorbate (E 202), established by the Panel on Food Additives and Nutrient Sources added to Food (ANS Panel) in 2015.	Potassium	356-365	ubiquitin specific peptidase 9 X-linked	Homo sapiens	67-70
30595123-4	2019	Several studies have found that the mTORC2 pathway is involved in the regulation of renal tubular sodium and potassium transport, but its role in hypertension has remained largely unexplored.	Potassium	109-118	CREB regulated transcription coactivator 2	Mus musculus	36-42
30813600-1	2019	The dysfunction of astrocytic inwardly rectifying potassium (Kir) 4.1 channels, which mediate the spatial potassium-buffering function of astrocytes, is known to be involved in the development of epilepsy.	Potassium	50-59	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	61-69
29861377-2	2019	The goals of this study were to describe the frequency of hypoglycemia following the use of insulin to shift potassium intracellularly and to examine the association of key variables with this complication.	Potassium	109-118	insulin	Homo sapiens	92-99
30172029-12	2019	CONCLUSION: This CACNA1C-E1115K variant destroyed the LTCC"s calcium selectivity and instead converted the mutant channel into a channel with a marked increase in sodium-mediated inward currents and potassium-mediated outward currents.	Potassium	199-208	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	17-24
30159893-2	2019	As the key regulator of tumor cell volume, sodium-potassium-chloride cotransporter 1 (NKCC1) expression increases along with the malignancy of the glioma, and NKCC1 has been implicated in glioblastoma invasion.	Potassium	50-59	solute carrier family 12, member 2	Mus musculus	86-91
30740538-5	2019	Intracellular acidification, by inhibiting glycolysis, works together with mitochondrial inhibition to induce intracellular ATP loss, which compromises intracellular potassium maintenance, a key event to NLRP3 inflammasome activation.	Potassium	166-175	NLR family pyrin domain containing 3	Homo sapiens	204-209
30740538-7	2019	Our work illustrates how energy metabolism converges upon intracellular potassium to activate NLRP3 inflammasome and highlights a biphasic relationship between cellular physiology and IL-1beta release.	Potassium	72-81	NLR family pyrin domain containing 3	Homo sapiens	94-99
30389838-2	2019	Here we report a major role of voltage-independent potassium (K+)-channel dysfunction in hyperexcitability of CA3 pyramidal neurons in Fmr1 knock-out (KO) mice.	Potassium	51-60	carbonic anhydrase 3	Mus musculus	110-113
30389838-2	2019	Here we report a major role of voltage-independent potassium (K+)-channel dysfunction in hyperexcitability of CA3 pyramidal neurons in Fmr1 knock-out (KO) mice.	Potassium	51-60	fragile X messenger ribonucleoprotein 1	Mus musculus	135-139
30589965-3	2019	A new potassium-competitive acid blocker (P-CAB) can rapidly block acid secretion.	Potassium	6-15	neural proliferation, differentiation and control 1	Homo sapiens	44-47
31192570-12	2019	In a multivariate analysis model, serum potassium (beta=1.41, p=0.010), male sex (beta=2.15, p=0.003), and HGS (beta=-0.088, p=0.021) were found as independent predictors of sleep quality.	Potassium	40-49	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	51-57
31588541-13	2019	Most commonly, neonatal diabetes is caused by mutations in KCNJ11 and ABCC8 genes encoding the ATP-dependent potassium channel of the beta cell.	Potassium	109-118	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	59-65
31588541-13	2019	Most commonly, neonatal diabetes is caused by mutations in KCNJ11 and ABCC8 genes encoding the ATP-dependent potassium channel of the beta cell.	Potassium	109-118	ATP binding cassette subfamily C member 8	Homo sapiens	70-75
31654968-9	2019	DISCUSSION: AKAP9 is a scaffolding protein that facilitates phosphorylation of delayed-rectifier potassium channels.	Potassium	97-106	A-kinase anchoring protein 9	Homo sapiens	12-17
31654968-10	2019	The AKAP9 variant alters potassium current causing disordered repolarization and ventricular reentry.	Potassium	25-34	A-kinase anchoring protein 9	Homo sapiens	4-9
30561082-0	2019	Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor.	Potassium	53-62	potassium inwardly rectifying channel subfamily J member 13	Homo sapiens	80-86
30868936-0	2019	Spinal glial cell line-derived neurotrophic factor infusion reverses reduction of Kv4.1-mediated A-type potassium currents of injured myelinated primary afferent neurons in a neuropathic pain model.	Potassium	104-113	glial cell derived neurotrophic factor	Rattus norvegicus	7-50
30868936-0	2019	Spinal glial cell line-derived neurotrophic factor infusion reverses reduction of Kv4.1-mediated A-type potassium currents of injured myelinated primary afferent neurons in a neuropathic pain model.	Potassium	104-113	potassium voltage-gated channel subfamily D member 1	Rattus norvegicus	82-87
30868936-3	2019	The fast-inactivating transient A-type potassium current (IA) is an important determinant of neuronal excitability, and five voltage-gated potassium channel (Kv) alpha-subunits, Kv1.4, Kv3.4, Kv4.1, Kv4.2, and Kv4.3, display IA in heterologous expression systems.	Potassium	39-48	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	178-183
30868936-3	2019	The fast-inactivating transient A-type potassium current (IA) is an important determinant of neuronal excitability, and five voltage-gated potassium channel (Kv) alpha-subunits, Kv1.4, Kv3.4, Kv4.1, Kv4.2, and Kv4.3, display IA in heterologous expression systems.	Potassium	39-48	potassium voltage-gated channel subfamily D member 1	Rattus norvegicus	192-197
30868936-3	2019	The fast-inactivating transient A-type potassium current (IA) is an important determinant of neuronal excitability, and five voltage-gated potassium channel (Kv) alpha-subunits, Kv1.4, Kv3.4, Kv4.1, Kv4.2, and Kv4.3, display IA in heterologous expression systems.	Potassium	39-48	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	199-204
30868936-3	2019	The fast-inactivating transient A-type potassium current (IA) is an important determinant of neuronal excitability, and five voltage-gated potassium channel (Kv) alpha-subunits, Kv1.4, Kv3.4, Kv4.1, Kv4.2, and Kv4.3, display IA in heterologous expression systems.	Potassium	39-48	potassium voltage-gated channel subfamily D member 3	Rattus norvegicus	210-215
31621014-2	2019	Interference with the hERG potassium ion channel may cause cardiac arrhythmia and can even lead to death.	Potassium	27-36	ETS transcription factor ERG	Homo sapiens	22-26
31787649-9	2019	Thus, careful monitoring of potassium levels in patients treated with TAZ/PIPC, particularly those aged >81 years, is warranted.	Potassium	28-37	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	70-73
30591705-1	2018	The mineralocorticoid receptor (MR) in mammals mediates the effects of aldosterone in regulating fluid balance and potassium homeostasis.	Potassium	115-124	nuclear receptor subfamily 3, group C, member 2	Danio rerio	4-30
30591705-1	2018	The mineralocorticoid receptor (MR) in mammals mediates the effects of aldosterone in regulating fluid balance and potassium homeostasis.	Potassium	115-124	nuclear receptor subfamily 3, group C, member 2	Danio rerio	32-34
30618766-6	2018	Therefore, here we investigated effects of the selective mu-opioid receptor (MOR) agonist [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin (DAMGO) on potassium conductance in DRG neurons upon a chronic constriction injury (CCI) of the sciatic nerve in mice.	Potassium	141-150	opioid receptor, mu 1	Mus musculus	57-75
30618766-13	2018	A comparative analysis of opioid-induced potassium conductance at the axonal injury site and peripheral terminals of DRG neurons could clarify the role of Kir3 channel-MOR interactions in peripheral nerve injury and opioid analgesia.	Potassium	41-50	opioid receptor, mu 1	Mus musculus	168-171
30647796-7	2018	In age-adjusted analyses, salivary potassium was significantly associated with carotid artery intima media thickness (cIMT) and carotid-femoral pulse wave velocity, and these associations were at the limit of significance in multivariate analyses including prevalent cardiovascular disease and risk factors.	Potassium	35-44	CIMT	Homo sapiens	118-122
29932955-4	2018	Lysosomal destabilization, efflux of cytosolic potassium ions and influx of calcium ions, signals from damaged mitochondria, both translational and post-translational controls, and prion-like polymerization have increasingly clear roles in regulating NLRP3 activation.	Potassium	47-56	NLR family pyrin domain containing 3	Homo sapiens	251-256
29981989-7	2018	The magnitude of Ks provides an idea about the bioavailable fraction of PCBs in the system; the higher the Ks, the greater the strength of sorption by the sorbent and therefore, the lower the PCB bioavailability.	Potassium	17-19	pyruvate carboxylase	Homo sapiens	72-75
29981989-7	2018	The magnitude of Ks provides an idea about the bioavailable fraction of PCBs in the system; the higher the Ks, the greater the strength of sorption by the sorbent and therefore, the lower the PCB bioavailability.	Potassium	107-109	pyruvate carboxylase	Homo sapiens	72-75
30218483-8	2018	In retinal arteries, NPY-induced vasoconstriction to a plateau of approximately 65% of potassium-induced constriction.	Potassium	87-96	neuropeptide Y	Sus scrofa	21-24
30323262-2	2018	The inwardly rectifying potassium channel (Kir) is a potassium-selective ion channel that allows potassium ions to move more easily into rather than out of the cell.	Potassium	24-33	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	43-46
30145795-0	2018	Long noncoding RNA MALAT1 downregulates cardiac transient outward potassium current by regulating miR-200c/HMGB1 pathway.	Potassium	66-75	microRNA 200c	Rattus norvegicus	98-106
30145795-0	2018	Long noncoding RNA MALAT1 downregulates cardiac transient outward potassium current by regulating miR-200c/HMGB1 pathway.	Potassium	66-75	high mobility group box 1	Rattus norvegicus	107-112
30063108-7	2018	In contrast, a negative correlation was found between S100A12 and the potassium concentration and pH of milk.	Potassium	70-79	S100 calcium binding protein A12	Bos taurus	54-61
30485804-3	2018	Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux.	Potassium	143-152	BCL2 associated X, apoptosis regulator	Homo sapiens	13-16
30485804-3	2018	Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux.	Potassium	143-152	BCL2 antagonist/killer 1	Homo sapiens	17-20
30485804-3	2018	Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux.	Potassium	143-152	NLR family pyrin domain containing 3	Homo sapiens	61-66
30485804-3	2018	Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux.	Potassium	143-152	caspase 1	Homo sapiens	89-98
30485804-3	2018	Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux.	Potassium	143-152	interleukin 1 alpha	Homo sapiens	109-117
30092543-5	2018	PM2.5 could be internalized into cells through multiple endocytosis processes, such as phagocytosis and pinocytosis (macropinocytosis, clathrin- and caveolin-mediated endocytosis), and activate NLRP3 inflammasome through cathepsin B release, ROS production, and potassium efflux.	Potassium	262-271	NLR family, pyrin domain containing 3	Mus musculus	194-199
29553285-6	2018	These data suggest weight-based insulin dosing is equally effective for lowering serum potassium and may lower risk of severe hypoglycemia.	Potassium	87-96	insulin	Homo sapiens	32-39
30571183-7	2018	The mutant Kv4.2 exhibited impaired response to PKC; hence, Kv4.2 membrane expression was augmented, enhancing potassium currents.	Potassium	111-120	potassium voltage-gated channel subfamily D member 2	Homo sapiens	11-16
30571183-7	2018	The mutant Kv4.2 exhibited impaired response to PKC; hence, Kv4.2 membrane expression was augmented, enhancing potassium currents.	Potassium	111-120	potassium voltage-gated channel subfamily D member 2	Homo sapiens	60-65
30766810-1	2018	Parathyroid hormone (PTH) is the main regulator of calcium, phosphate, magnesium, sodium, and potassium homeostasis.	Potassium	94-103	parathyroid hormone	Homo sapiens	0-19
30766810-1	2018	Parathyroid hormone (PTH) is the main regulator of calcium, phosphate, magnesium, sodium, and potassium homeostasis.	Potassium	94-103	parathyroid hormone	Homo sapiens	21-24
30190339-2	2018	As oxidative injury leads to the intracellular liberation of zinc, we hypothesize that tapping onto the zinc-activated metal regulatory element (MRE) transcription factor 1 system to drive expression of the Kv2.1-targeted hepatitis C protein NS5A (hepatitis C nonstructural protein 5A) will provide neuroprotection by preventing cell death-enabling cellular potassium loss in rat cortical neurons in vitro.	Potassium	358-367	potassium voltage-gated channel subfamily B member 1	Homo sapiens	207-212
30190339-4	2018	Further, we report that MRE-driven NS5A expression, induced by a slowly evolving excitotoxic stimulus, functionally blocks injurious, enhanced Kv2.1 potassium whole-cell currents and improves neuronal viability.	Potassium	149-158	potassium voltage-gated channel subfamily B member 1	Homo sapiens	143-148
30416361-7	2018	The applied melatonin prevented potassium and intracellular enzyme leakage (CK and LDH) that was induced by CCl4, as well as an increase in tissue MDA.	Potassium	32-41	C-C motif chemokine ligand 4	Rattus norvegicus	108-112
30405539-2	2018	In Saccharomyces cerevisiae, the serine/threonine (S/T) kinase Sat4/Hal4 is required for potassium accumulation, and thus, regulates the resistance to sodium salts and helps in the stabilization of other plasma membrane transporters.	Potassium	89-98	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	63-67
30405539-2	2018	In Saccharomyces cerevisiae, the serine/threonine (S/T) kinase Sat4/Hal4 is required for potassium accumulation, and thus, regulates the resistance to sodium salts and helps in the stabilization of other plasma membrane transporters.	Potassium	89-98	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	68-72
30356026-3	2018	Inwardly rectifying potassium (Kir) channel subunit Kir4.1, which is specifically expressed in astrocytes, constructs Kir4.1 and Kir4.1/5.1 channels, and mediates the spatial potassium (K+) buffering action of astrocytes.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
30356026-3	2018	Inwardly rectifying potassium (Kir) channel subunit Kir4.1, which is specifically expressed in astrocytes, constructs Kir4.1 and Kir4.1/5.1 channels, and mediates the spatial potassium (K+) buffering action of astrocytes.	Potassium	20-29	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	52-58
30356026-3	2018	Inwardly rectifying potassium (Kir) channel subunit Kir4.1, which is specifically expressed in astrocytes, constructs Kir4.1 and Kir4.1/5.1 channels, and mediates the spatial potassium (K+) buffering action of astrocytes.	Potassium	20-29	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	118-124
30356026-3	2018	Inwardly rectifying potassium (Kir) channel subunit Kir4.1, which is specifically expressed in astrocytes, constructs Kir4.1 and Kir4.1/5.1 channels, and mediates the spatial potassium (K+) buffering action of astrocytes.	Potassium	20-29	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	118-124
30353147-4	2018	Using our TPA model, we have demonstrated that spontaneous diastolic depolarization observed in atrial myocytes with TBX5-deletion can be explained by altered intracellular calcium handling and suppression of inward-rectifier potassium current (IK1).	Potassium	226-235	T-box transcription factor 5	Homo sapiens	117-121
29935238-8	2018	atp8 and nad2 showed the lowest similarity and the highest Ka/Ks ratios, indicating that both genes have potential for studying species identification and populations genetics in apple snails.	Potassium	62-64	ATP synthase F0 subunit 8	Malus domestica	0-4
29935238-8	2018	atp8 and nad2 showed the lowest similarity and the highest Ka/Ks ratios, indicating that both genes have potential for studying species identification and populations genetics in apple snails.	Potassium	62-64	NADH dehydrogenase subunit 2	Malus domestica	9-13
30189384-5	2018	Serum analyses revealed the presence of anti-neuronal antibodies directed against anti-contactin-associated protein 2 (anti-Caspr2), a protein associated with voltage-gated potassium neuronal channels.	Potassium	173-182	contactin associated protein 2	Homo sapiens	124-130
30120881-1	2018	Na+ , K+ -ATPase (NKA) activity, which establishes the sodium and potassium gradient across the cell membrane and is instrumental in the propagation of the nerve impulses, is altered in a number of neurological and neuropsychiatric disorders, including autism spectrum disorders (ASD).	Potassium	66-75	tachykinin precursor 1	Homo sapiens	0-16
30120881-1	2018	Na+ , K+ -ATPase (NKA) activity, which establishes the sodium and potassium gradient across the cell membrane and is instrumental in the propagation of the nerve impulses, is altered in a number of neurological and neuropsychiatric disorders, including autism spectrum disorders (ASD).	Potassium	66-75	tachykinin precursor 1	Homo sapiens	18-21
30054673-10	2018	Glucose-stimulated first-phase insulin secretion and potassium-stimulated insulin secretion decreased by 53% and 59%, respectively, in perfused pancreases of 10-week-old Wfs1-/- mice compared with wild-type (WT) mice.	Potassium	53-62	insulin	Homo sapiens	74-81
30054673-10	2018	Glucose-stimulated first-phase insulin secretion and potassium-stimulated insulin secretion decreased by 53% and 59%, respectively, in perfused pancreases of 10-week-old Wfs1-/- mice compared with wild-type (WT) mice.	Potassium	53-62	wolframin ER transmembrane glycoprotein	Mus musculus	170-174
30153627-2	2018	KCNQ4 channels are crucial to the internal ear potassium recycling.	Potassium	47-56	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	0-5
30323912-0	2018	An association of urinary sodium-potassium ratio with insulin resistance among Korean adults.	Potassium	33-42	insulin	Homo sapiens	54-61
30323912-1	2018	BACKGROUND/OBJECTIVES: This study was conducted to investigate the effects of sodium-potassium ratio on insulin resistance and sensitivity in Korean adults.	Potassium	85-94	insulin	Homo sapiens	104-111
30323912-5	2018	The generalized linear model was applied to determine the association between urinary sodium-potassium ratio and insulin resistance.	Potassium	93-102	insulin	Homo sapiens	113-120
30323912-8	2018	CONCLUSION: The present study suggests that high sodium-potassium ratio is related to high insulin resistance and low insulin sensitivity.	Potassium	56-65	insulin	Homo sapiens	91-98
30323912-8	2018	CONCLUSION: The present study suggests that high sodium-potassium ratio is related to high insulin resistance and low insulin sensitivity.	Potassium	56-65	insulin	Homo sapiens	118-125
30323912-9	2018	Decreasing sodium intake and increasing potassium intake are important for maintaining insulin sensitivity.	Potassium	40-49	insulin	Homo sapiens	87-94
29969132-8	2018	A possible open state of the TMEM175 channel was modelled by the in silico expansion of the hydrophobic gate resulting in the wetting of the pore and free permeation of potassium ions through the channel.	Potassium	169-178	transmembrane protein 175	Homo sapiens	29-36
30260982-10	2018	When neurites of NGF cultured somata were grown in GDNF, capsaicin evoked a lower CGRP release than high potassium, compared to those grown in NGF.	Potassium	105-114	nerve growth factor	Mus musculus	17-20
30254284-5	2018	Membrane depolarization by high extracellular potassium maintained PSD-95 puncta density and partially rescued both spontaneous synaptic activity and cell death, while spike generation remained blocked.	Potassium	46-55	discs large MAGUK scaffold protein 4	Homo sapiens	67-73
30231975-3	2018	(2018) document how GSDMD triggers potassium efflux to inhibit cGAS-STING and prevent damaging interferon production after bacterial infection.	Potassium	35-44	gasdermin D	Homo sapiens	20-25
30254424-0	2018	Saikosaponin A modulates remodeling of Kv4.2-mediated A-type voltage-gated potassium currents in rat chronic temporal lobe epilepsy.	Potassium	75-84	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	39-44
30185776-7	2018	Finally, SARS 3a activates caspase-1 either directly or via an enhanced potassium efflux, which triggers NLRP3 inflammasome assembly.	Potassium	72-81	seryl-tRNA synthetase 1	Homo sapiens	9-13
30185776-7	2018	Finally, SARS 3a activates caspase-1 either directly or via an enhanced potassium efflux, which triggers NLRP3 inflammasome assembly.	Potassium	72-81	caspase 1	Homo sapiens	27-36
30185776-7	2018	Finally, SARS 3a activates caspase-1 either directly or via an enhanced potassium efflux, which triggers NLRP3 inflammasome assembly.	Potassium	72-81	NLR family pyrin domain containing 3	Homo sapiens	105-110
30838349-12	2018	Molecular modelling showed Kir2.2 p.Thr140Met to reduce movement of potassium ions towards binding sites in the hetero-tetramer pore compatible with a reduced maximal current.	Potassium	68-77	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	27-33
29846116-9	2018	KS-WNK1-mediated activation of WNK4 is not due to a decrease of the [Cl-]i. Coimmunoprecipitation analysis revealed that KS-WNK1 and WNK4 interact with each other and that WNK4 becomes autophosphorylated at serine 335 when it is associated with KS-WNK1.	Potassium	0-2	WNK lysine deficient protein kinase 1	Homo sapiens	124-128
29846116-3	2018	The role played by KS-WNK1 in the modulation of the WNK/STE20-proline-alanine rich kinase (SPAK)/NCC pathway remains elusive.	Potassium	19-21	WNK lysine deficient protein kinase 1	Homo sapiens	22-26
29846116-3	2018	The role played by KS-WNK1 in the modulation of the WNK/STE20-proline-alanine rich kinase (SPAK)/NCC pathway remains elusive.	Potassium	19-21	serine/threonine kinase 39	Homo sapiens	91-95
29846116-6	2018	The effect of KS-WNK1 was abrogated by eliminating a WNK-WNK-interacting domain and by a specific WNK inhibitor, WNK463, indicating that the activation of SPAK/NCC by KS-WNK1 is due to interaction with another WNK kinase.	Potassium	14-16	WNK lysine deficient protein kinase 1	Homo sapiens	17-21
29846116-6	2018	The effect of KS-WNK1 was abrogated by eliminating a WNK-WNK-interacting domain and by a specific WNK inhibitor, WNK463, indicating that the activation of SPAK/NCC by KS-WNK1 is due to interaction with another WNK kinase.	Potassium	14-16	serine/threonine kinase 39	Homo sapiens	155-159
29846116-6	2018	The effect of KS-WNK1 was abrogated by eliminating a WNK-WNK-interacting domain and by a specific WNK inhibitor, WNK463, indicating that the activation of SPAK/NCC by KS-WNK1 is due to interaction with another WNK kinase.	Potassium	14-16	WNK lysine deficient protein kinase 1	Homo sapiens	170-174
29846116-6	2018	The effect of KS-WNK1 was abrogated by eliminating a WNK-WNK-interacting domain and by a specific WNK inhibitor, WNK463, indicating that the activation of SPAK/NCC by KS-WNK1 is due to interaction with another WNK kinase.	Potassium	167-169	WNK lysine deficient protein kinase 1	Homo sapiens	17-21
29846116-6	2018	The effect of KS-WNK1 was abrogated by eliminating a WNK-WNK-interacting domain and by a specific WNK inhibitor, WNK463, indicating that the activation of SPAK/NCC by KS-WNK1 is due to interaction with another WNK kinase.	Potassium	167-169	serine/threonine kinase 39	Homo sapiens	155-159
29846116-6	2018	The effect of KS-WNK1 was abrogated by eliminating a WNK-WNK-interacting domain and by a specific WNK inhibitor, WNK463, indicating that the activation of SPAK/NCC by KS-WNK1 is due to interaction with another WNK kinase.	Potassium	167-169	WNK lysine deficient protein kinase 1	Homo sapiens	170-174
29846116-8	2018	In contrast, this serine becomes phosphorylated when the intracellular chloride concentration ([Cl-]i) is reduced or when KS-WNK1 is coexpressed with WNK4.	Potassium	122-124	WNK lysine deficient protein kinase 1	Homo sapiens	125-129
29846116-8	2018	In contrast, this serine becomes phosphorylated when the intracellular chloride concentration ([Cl-]i) is reduced or when KS-WNK1 is coexpressed with WNK4.	Potassium	122-124	WNK lysine deficient protein kinase 4	Homo sapiens	150-154
29846116-9	2018	KS-WNK1-mediated activation of WNK4 is not due to a decrease of the [Cl-]i. Coimmunoprecipitation analysis revealed that KS-WNK1 and WNK4 interact with each other and that WNK4 becomes autophosphorylated at serine 335 when it is associated with KS-WNK1.	Potassium	0-2	WNK lysine deficient protein kinase 1	Homo sapiens	3-7
29846116-9	2018	KS-WNK1-mediated activation of WNK4 is not due to a decrease of the [Cl-]i. Coimmunoprecipitation analysis revealed that KS-WNK1 and WNK4 interact with each other and that WNK4 becomes autophosphorylated at serine 335 when it is associated with KS-WNK1.	Potassium	0-2	WNK lysine deficient protein kinase 4	Homo sapiens	31-35
29846116-9	2018	KS-WNK1-mediated activation of WNK4 is not due to a decrease of the [Cl-]i. Coimmunoprecipitation analysis revealed that KS-WNK1 and WNK4 interact with each other and that WNK4 becomes autophosphorylated at serine 335 when it is associated with KS-WNK1.	Potassium	0-2	WNK lysine deficient protein kinase 1	Homo sapiens	124-128
29846116-9	2018	KS-WNK1-mediated activation of WNK4 is not due to a decrease of the [Cl-]i. Coimmunoprecipitation analysis revealed that KS-WNK1 and WNK4 interact with each other and that WNK4 becomes autophosphorylated at serine 335 when it is associated with KS-WNK1.	Potassium	0-2	WNK lysine deficient protein kinase 4	Homo sapiens	133-137
29846116-9	2018	KS-WNK1-mediated activation of WNK4 is not due to a decrease of the [Cl-]i. Coimmunoprecipitation analysis revealed that KS-WNK1 and WNK4 interact with each other and that WNK4 becomes autophosphorylated at serine 335 when it is associated with KS-WNK1.	Potassium	0-2	WNK lysine deficient protein kinase 4	Homo sapiens	133-137
29767559-9	2018	In addition, feeding a high-potassium diet significantly increased both GPS2 and BK protein abundance in mice.	Potassium	28-37	G protein pathway suppressor 2	Mus musculus	72-76
29958895-7	2018	Here, using the established bioconjugation methodology, we show how steroid bioconjugation at the allosteric site affects the heme spin state, the binding affinity (KS) of CYP3A4 for testosterone, as well as the enzyme coupling efficiency.	Potassium	165-167	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	172-178
29894319-5	2018	It was reported that Kir4.1/Kir5.1 serves as potassium sensors in the distal nephron responding to variations in dietary intake and hormonal stimuli.	Potassium	45-54	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	21-27
29894319-5	2018	It was reported that Kir4.1/Kir5.1 serves as potassium sensors in the distal nephron responding to variations in dietary intake and hormonal stimuli.	Potassium	45-54	potassium inwardly-rectifying channel, subfamily J, member 16	Rattus norvegicus	28-34
29957655-8	2018	Whereas renal potassium reabsorption is mediated by upregulation of potassium retaining transporters (HKA2) and downregulation of potassium secreting channels (ROMK, BK).	Potassium	14-23	keratin 32	Homo sapiens	102-106
29957655-8	2018	Whereas renal potassium reabsorption is mediated by upregulation of potassium retaining transporters (HKA2) and downregulation of potassium secreting channels (ROMK, BK).	Potassium	14-23	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	160-164
30146013-11	2018	Thus, we demonstrate an important contribution of pendrin in renal regulation of sodium chloride, potassium and acid-base homeostasis and in the pathophysiology of PHAII.	Potassium	98-107	solute carrier family 26, member 4	Mus musculus	50-57
30161182-1	2018	The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (Gi/o) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents.	Potassium	241-250	prepronociceptin	Cricetulus griseus	4-14
30161182-1	2018	The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (Gi/o) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents.	Potassium	241-250	prepronociceptin	Homo sapiens	43-46
29995632-7	2018	Serum insulin, cortisol and glucose did not correlate with IGF-I concentrations, but serum potassium showed a negative correlation (rho=-0.364; p&lt;0.0001) with IGF-I concentrations.	Potassium	91-100	insulin like growth factor 1	Homo sapiens	162-167
29995632-10	2018	The inverse correlation of IGF-I and serum potassium concentrations after injections of rhIGF-I has not been reported before and warrants further consideration.	Potassium	43-52	insulin like growth factor 1	Homo sapiens	27-32
29976759-7	2018	Moreover, inhibiting cellular potassium efflux with glyburide or increasing extracellular potassium also significantly reduced SAA-mediated IL-1beta secretion.	Potassium	30-39	serum amyloid A cluster	Mus musculus	127-130
29976759-7	2018	Moreover, inhibiting cellular potassium efflux with glyburide or increasing extracellular potassium also significantly reduced SAA-mediated IL-1beta secretion.	Potassium	30-39	interleukin 1 beta	Mus musculus	140-148
29976759-7	2018	Moreover, inhibiting cellular potassium efflux with glyburide or increasing extracellular potassium also significantly reduced SAA-mediated IL-1beta secretion.	Potassium	90-99	serum amyloid A cluster	Mus musculus	127-130
29976759-7	2018	Moreover, inhibiting cellular potassium efflux with glyburide or increasing extracellular potassium also significantly reduced SAA-mediated IL-1beta secretion.	Potassium	90-99	interleukin 1 beta	Mus musculus	140-148
31665287-4	2019	In mouse sperm, the potassium current has been conclusively shown to be carried by a channel consisting of the pore forming subunit SLO3 and auxiliary subunit leucine-rich repeat-containing 52 (LRRC52).	Potassium	20-29	potassium channel, subfamily U, member 1	Mus musculus	132-136
31665287-4	2019	In mouse sperm, the potassium current has been conclusively shown to be carried by a channel consisting of the pore forming subunit SLO3 and auxiliary subunit leucine-rich repeat-containing 52 (LRRC52).	Potassium	20-29	leucine rich repeat containing 52	Mus musculus	159-192
31665287-4	2019	In mouse sperm, the potassium current has been conclusively shown to be carried by a channel consisting of the pore forming subunit SLO3 and auxiliary subunit leucine-rich repeat-containing 52 (LRRC52).	Potassium	20-29	leucine rich repeat containing 52	Mus musculus	194-200
31879517-8	2019	The modulation of PCS on IK was through regulation of the phosphorylation of the major potassium ion channel protein Kv2.1.	Potassium	87-96	potassium voltage-gated channel subfamily B member 1	Homo sapiens	117-122
31347753-3	2019	This study proposes an artificial neural network (ANN) for noninvasive electrocardiography-based classification of the hERG potassium-channel block.	Potassium	124-133	ETS transcription factor ERG	Homo sapiens	119-123
31659098-1	2019	BACKGROUND/AIM: hERG potassium channels enhance tumor invasiveness and breast cancer proliferation.	Potassium	21-30	ETS transcription factor ERG	Homo sapiens	16-20
31526813-6	2019	Effects of reference compounds were in accordance with the literature, indicating the presence of hERG potassium (dofetilide), sodium (mexiletine) and calcium (nifedipine) channels and alpha-adrenergic receptors (isoproterenol).	Potassium	103-112	ETS transcription factor ERG	Homo sapiens	98-102
31408542-0	2019	Melatonin receptor activation protects against low potassium-induced ventricular fibrillation by preserving action potentials and connexin-43 topology in isolated rat hearts.	Potassium	51-60	gap junction protein, alpha 1	Rattus norvegicus	130-141
31408542-3	2019	We hypothesized that melatonin protects against low potassium-induced arrhythmias through the activation of its receptors, resulting in action potential shortening and connexin-43 preservation.	Potassium	52-61	gap junction protein, alpha 1	Rattus norvegicus	168-179
31369814-5	2019	In isolated femoral arteries from endothelial nitric oxide synthase knockout (eNOS-/-) mice, RV had no overall effect on FMD, but potentiated ACh induced dilation, that was completely abolished by potassium channel blockers, Apamin and Tram 34 (p < 0.01).	Potassium	197-206	nitric oxide synthase 3, endothelial cell	Mus musculus	78-82
31708743-2	2019	In this study, we found that pan-histone deacetylase (HDAC) inhibition by TSA, SAHA, VPA, and M344 led to a remarkable decrease in the phosphorylation of JNK and c-Jun, concomitant with a significant abrogation of apoptosis caused by potassium deprivation in cultured cerebellar granule neurons (CGNs).	Potassium	234-243	mitogen-activated protein kinase 8	Rattus norvegicus	154-157
31708743-6	2019	Functionally, HDAC4 inhibition via knockdown or LMK235 significantly rescued CGN apoptosis induced by potassium deprivation.	Potassium	102-111	histone deacetylase 4	Rattus norvegicus	14-19
31708743-6	2019	Functionally, HDAC4 inhibition via knockdown or LMK235 significantly rescued CGN apoptosis induced by potassium deprivation.	Potassium	102-111	cingulin	Rattus norvegicus	77-80
31424260-6	2019	Four of the differentially expressed genes (Per1, Nr4a1, Nr4a3, Kcna5) belong to circadian rhythm pathways, aldosterone synthesis and secretion, PI3K-Akt signaling pathway and potassium homeostasis.	Potassium	176-185	nuclear receptor subfamily 4, group A, member 1	Rattus norvegicus	50-55
31424260-6	2019	Four of the differentially expressed genes (Per1, Nr4a1, Nr4a3, Kcna5) belong to circadian rhythm pathways, aldosterone synthesis and secretion, PI3K-Akt signaling pathway and potassium homeostasis.	Potassium	176-185	nuclear receptor subfamily 4, group A, member 3	Rattus norvegicus	57-62
31424260-6	2019	Four of the differentially expressed genes (Per1, Nr4a1, Nr4a3, Kcna5) belong to circadian rhythm pathways, aldosterone synthesis and secretion, PI3K-Akt signaling pathway and potassium homeostasis.	Potassium	176-185	potassium voltage-gated channel subfamily A member 5	Rattus norvegicus	64-69
31614948-6	2019	The nutrient-to-energy ratio for vitamins A, B1, B2, B6, C, folate and minerals Calcium, copper, iron, magnesium, phosphorus, potassium and zinc increased significantly.	Potassium	126-135	immunoglobulin kappa variable 5-2	Homo sapiens	33-55
31601020-0	2019	Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels.	Potassium	6-15	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	109-112
31601020-2	2019	In the kidney, HCN1, HCN2 and HCN3 are differentially expressed and contribute to the transport of sodium, potassium (K+) and ammonium into the nephrons.	Potassium	107-116	hyperpolarization activated cyclic nucleotide gated potassium channel 1	Homo sapiens	15-19
31601020-2	2019	In the kidney, HCN1, HCN2 and HCN3 are differentially expressed and contribute to the transport of sodium, potassium (K+) and ammonium into the nephrons.	Potassium	107-116	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Homo sapiens	21-25
31601020-2	2019	In the kidney, HCN1, HCN2 and HCN3 are differentially expressed and contribute to the transport of sodium, potassium (K+) and ammonium into the nephrons.	Potassium	107-116	hyperpolarization activated cyclic nucleotide gated potassium channel 3	Homo sapiens	30-34
31591393-0	2019	Correction: Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain.	Potassium	31-40	potassium voltage-gated channel subfamily B member 1	Homo sapiens	25-30
31511304-1	2019	Inwardly rectifying potassium (Kir) channels play a key role in controlling membrane potentials in excitable and unexcitable cells, thereby regulating a plethora of physiological processes.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
31686980-11	2019	Immediately after the marathon race, we observed a negative correlation between IL-8 and daily EI, carbohydrate, fiber, fat, iron, calcium, potassium, and sodium intakes, and higher levels of IL-8 on runners with <3 g/kg/day of carbohydrate intake compared to runners with >5 g/kg/day.	Potassium	140-149	C-X-C motif chemokine ligand 8	Homo sapiens	80-84
31632394-4	2019	This process is partially mediated through the potassium efflux-dependent, cytosolic, PYCARD-containing inflammasome protein complex.	Potassium	47-56	PYD and CARD domain containing	Homo sapiens	86-92
31632394-6	2019	Using the NLRP3 inflammasome-deficient Raw 264.7 and PYCARD-deficient J77 macrophages, which both lack PYCARD, we found that the potassium efflux activator nigericin enhances bacterial killing.	Potassium	129-138	NLR family pyrin domain containing 3	Homo sapiens	10-15
31632394-6	2019	Using the NLRP3 inflammasome-deficient Raw 264.7 and PYCARD-deficient J77 macrophages, which both lack PYCARD, we found that the potassium efflux activator nigericin enhances bacterial killing.	Potassium	129-138	PYD and CARD domain containing	Homo sapiens	53-59
31004291-7	2019	After being treated with etoricoxib, the serum potassium level of the patient increased rapidly to the normal range which corresponded with the reduction in his serum PGE2 and PE2 metabolite (PGEM) levels.	Potassium	47-56	ETS2 repressor factor	Homo sapiens	176-179
31425886-9	2019	Ks correlated with fibrinogen-gamma and PF4 amounts within plasma clots.	Potassium	0-2	platelet factor 4	Homo sapiens	40-43
31562289-8	2019	We conclude that this Gjb2 mutation-induced hearing loss results from 1) reduced cochlear amplifier caused by lowered EP, 2) IHCs excitotoxicity associated with potassium accumulation around hair cells, and 3) progression induced by environmental insults.	Potassium	161-170	gap junction protein, beta 2	Mus musculus	22-26
31559333-4	2019	Materials and Methods: Potassium channel activity in AtT20 FlpIn cells transfected with human CB1 or CB2 receptors was measured in real time using FLIPR  membrane potential dye in a FlexStation 3 plate reader.	Potassium	23-32	cannabinoid receptor 1	Homo sapiens	94-97
31559333-4	2019	Materials and Methods: Potassium channel activity in AtT20 FlpIn cells transfected with human CB1 or CB2 receptors was measured in real time using FLIPR  membrane potential dye in a FlexStation 3 plate reader.	Potassium	23-32	cannabinoid receptor 2	Homo sapiens	101-104
31854846-15	2019	In addition, EC1 also had stronger interrelation with potassium.	Potassium	54-63	Susceptibility to lysis by alloreactive natural killer cells	Homo sapiens	13-16
31479495-7	2019	We also determined that MAYV triggers NLRP3 inflammasome activation by inducing reactive oxygen species (ROS) and potassium efflux.	Potassium	114-123	NLR family pyrin domain containing 3	Homo sapiens	38-43
31085235-12	2019	Further, PACAP blocks voltage-dependent potassium currents via the adenylyl cyclase/protein kinase A signaling pathway.	Potassium	40-49	adenylate cyclase activating polypeptide 1	Rattus norvegicus	9-14
31085235-12	2019	Further, PACAP blocks voltage-dependent potassium currents via the adenylyl cyclase/protein kinase A signaling pathway.	Potassium	40-49	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	84-100
31409147-0	2019	Oligodendrocyte Kir4.1 Channels Clear Out Congested K. Oligodendrocytes Control Potassium Accumulation in White Matter and Seizure Susceptibility.	Potassium	80-89	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	16-22
33391853-23	2019	KS was given a diagnosis of clinical stage T1b, N0, grade 2 invasive micropapillary carcinoma: ER positive (Allred 6), PR positive (Allred 8), HER2/neu, immunohistochemistry 3+, and fluorescence in situ hybridization amplified.After discussion of this recurrent cancer diagnosis, her team opted for a bilateral diagnostic mammogram (with abdominal shielding) and bilateral axillary and breast ultrasound to evaluate the contralateral breast and lymph nodes.	Potassium	0-2	estrogen receptor 1	Homo sapiens	95-97
33391853-23	2019	KS was given a diagnosis of clinical stage T1b, N0, grade 2 invasive micropapillary carcinoma: ER positive (Allred 6), PR positive (Allred 8), HER2/neu, immunohistochemistry 3+, and fluorescence in situ hybridization amplified.After discussion of this recurrent cancer diagnosis, her team opted for a bilateral diagnostic mammogram (with abdominal shielding) and bilateral axillary and breast ultrasound to evaluate the contralateral breast and lymph nodes.	Potassium	0-2	erb-b2 receptor tyrosine kinase 2	Homo sapiens	143-147
33391853-23	2019	KS was given a diagnosis of clinical stage T1b, N0, grade 2 invasive micropapillary carcinoma: ER positive (Allred 6), PR positive (Allred 8), HER2/neu, immunohistochemistry 3+, and fluorescence in situ hybridization amplified.After discussion of this recurrent cancer diagnosis, her team opted for a bilateral diagnostic mammogram (with abdominal shielding) and bilateral axillary and breast ultrasound to evaluate the contralateral breast and lymph nodes.	Potassium	0-2	erb-b2 receptor tyrosine kinase 2	Homo sapiens	148-151
30897250-7	2019	This mechanism also promotes IL-1beta release and potassium efflux that connects caspase-11 to NLRP3 activation.	Potassium	50-59	NLR family pyrin domain containing 3	Homo sapiens	95-100
31270663-2	2019	Voltage-dependent potassium conductances such as those formed by Kv1.1 are important for the ability of VOR circuit elements to encode highly transient motion components.	Potassium	18-27	potassium channel, voltage gated shaker related subfamily A, member 1 S homeolog	Xenopus laevis	65-70
31555089-8	2019	For the in vitro analysis, primary cortical neurons with NEK7-shRNA were stimulated with lipopolysaccharide (LPS)/ATP or potassium (K+).	Potassium	121-130	NIMA (never in mitosis gene a)-related expressed kinase 7	Mus musculus	57-61
31361119-5	2019	The superior sodium/potassium storage performance of the OC/SeS2 composite electrodes stems from their rational chemical structure design, including high electrical conductivity of the N-doped organic carbon network and chemical binding with SeS2 molecules.	Potassium	20-29	secernin 2	Homo sapiens	60-64
31361119-6	2019	As a result, the OC/SeS2 cathode delivers a reversible capacity of 416 mAh g-1 after 700 cycles for sodium-ion batteries and 216 mAh g-1 after 500 cycles for potassium-ion batteries at 0.5 A g-1, respectively.	Potassium	158-167	secernin 2	Homo sapiens	20-24
30872118-9	2019	APOE-dependent NLRP3 inflammasome activation in macrophages was primarily mediated through a potassium efflux-dependent mechanism.	Potassium	93-102	apolipoprotein E	Mus musculus	0-4
30872118-9	2019	APOE-dependent NLRP3 inflammasome activation in macrophages was primarily mediated through a potassium efflux-dependent mechanism.	Potassium	93-102	NLR family pyrin domain containing 3	Homo sapiens	15-20
31239388-0	2019	Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium during Increased Dietary Potassium Intake.	Potassium	52-61	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	12-18
31239388-0	2019	Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium during Increased Dietary Potassium Intake.	Potassium	87-96	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	12-18
31239388-1	2019	BACKGROUND: The basolateral potassium channel in the distal convoluted tubule (DCT), comprising the inwardly rectifying potassium channel Kir4.1/Kir5.1 heterotetramer, plays a key role in mediating the effect of dietary potassium intake on the thiazide-sensitive NaCl cotransporter (NCC).	Potassium	28-37	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	138-144
31239388-1	2019	BACKGROUND: The basolateral potassium channel in the distal convoluted tubule (DCT), comprising the inwardly rectifying potassium channel Kir4.1/Kir5.1 heterotetramer, plays a key role in mediating the effect of dietary potassium intake on the thiazide-sensitive NaCl cotransporter (NCC).	Potassium	28-37	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	145-151
31239388-2	2019	The role of Kir5.1 (encoded by Kcnj16) in mediating effects of dietary potassium intake on the NCC and renal potassium excretion is unknown.	Potassium	71-80	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	12-18
30887515-10	2019	In conclusion, our data suggested that potassium currents might play a role in the maintenance of overall S17 cell ionic homeostasis directly affecting cell survival and migration.	Potassium	39-48	sperm associated antigen 5	Mus musculus	106-109
29513112-9	2019	The Atp1a2+/-G301R MCA constricted stronger to U46619, endothelin and potassium compared to WT.	Potassium	70-79	ATPase, Na+/K+ transporting, alpha 2 polypeptide	Mus musculus	4-10
30964070-8	2019	The results showed that fibroblast growth factor 20 decreased A-type potassium current in neurons of the substantia nigra, increased long-term potentiation amplitude in the hippocampus, and downregulated Kv4.2 expression.	Potassium	69-78	fibroblast growth factor 20	Mus musculus	24-51
31101453-7	2019	Whether conservation of osmotic homeostasis by LETM1 occurs by extrusion of excess mitochondrial potassium (K+), calcium (Ca2+), or both has been a matter of dispute over the past 10 years.	Potassium	97-106	leucine zipper and EF-hand containing transmembrane protein 1	Homo sapiens	47-52
31453296-6	2019	In T1D patients, we show that secretion of cytokines IL-1beta, TNFalpha, IL-6 and IFNalpha after microbial DNA stimulation is promoted by potassium efflux and is not dependent on P2X7 receptor signaling.	Potassium	138-147	interleukin 1 beta	Homo sapiens	53-61
31453296-6	2019	In T1D patients, we show that secretion of cytokines IL-1beta, TNFalpha, IL-6 and IFNalpha after microbial DNA stimulation is promoted by potassium efflux and is not dependent on P2X7 receptor signaling.	Potassium	138-147	tumor necrosis factor	Homo sapiens	63-71
31453296-6	2019	In T1D patients, we show that secretion of cytokines IL-1beta, TNFalpha, IL-6 and IFNalpha after microbial DNA stimulation is promoted by potassium efflux and is not dependent on P2X7 receptor signaling.	Potassium	138-147	interleukin 6	Homo sapiens	73-77
31453296-6	2019	In T1D patients, we show that secretion of cytokines IL-1beta, TNFalpha, IL-6 and IFNalpha after microbial DNA stimulation is promoted by potassium efflux and is not dependent on P2X7 receptor signaling.	Potassium	138-147	interferon alpha 1	Homo sapiens	82-90
31082369-4	2019	Chloroquine also inhibited the outward potassium currents from MDA-MB-231 cells, which are mainly carried through Kv10.1 channels as was confirmed using astemizole.	Potassium	39-48	potassium voltage-gated channel modifier subfamily G member 3	Homo sapiens	114-120
31296940-0	2019	Evidence for potassium transport activity of Arabidopsis KEA1-KEA6.	Potassium	13-22	K+ efflux antiporter 1	Arabidopsis thaliana	57-61
31061086-13	2019	This study uncovers a hitherto uncharacterized consequence of rhodopsin mislocalization: the activation of the lysosomal pathway, which negatively regulates the amount of the sodium-potassium ATPase (NKAalpha) on the inner segment plasma membrane.	Potassium	182-191	rhodopsin	Homo sapiens	62-71
31208990-0	2019	Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (I K,ACh).	Potassium	122-131	G protein subunit beta 5	Homo sapiens	21-25
31636949-4	2019	Through systematic profiling studies, we show that human SIRT3 displays class-selective histone de-beta-hydroxybutyrylase activities with preference for H3 K4, K9, K18, K23, K27, and H4K16, but not for H4 K5, K8, K12, which distinguishes it from the Zn-dependent HDACs.	Potassium	156-158	sirtuin 3	Homo sapiens	57-62
31269062-10	2019	The treatment with V2R antagonist (V2A) in the presence and absence of OT induced diuresis, sodium and potassium outflow.	Potassium	103-112	arginine vasopressin receptor 2	Rattus norvegicus	19-22
31237175-9	2019	Urinary potassium strongly correlated with urinary AGT ( P<0.0001).	Potassium	8-17	angiotensinogen	Homo sapiens	51-54
31946488-2	2019	The SQT1, SQT2 and SQT3 variants of the SQTS result from inherited gain-of-function mutations (e.g. N588K, V307L and D172N, respectively) to potassium channels.	Potassium	141-150	potassium voltage-gated channel subfamily H member 2	Homo sapiens	4-8
31946488-2	2019	The SQT1, SQT2 and SQT3 variants of the SQTS result from inherited gain-of-function mutations (e.g. N588K, V307L and D172N, respectively) to potassium channels.	Potassium	141-150	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	10-14
31946488-2	2019	The SQT1, SQT2 and SQT3 variants of the SQTS result from inherited gain-of-function mutations (e.g. N588K, V307L and D172N, respectively) to potassium channels.	Potassium	141-150	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	19-23
31946747-2	2019	Previous experimental studies have shown that biological pacemaker could be produced by genetically manipulating non-pacemaking cardiac cells by suppressing the inward rectifier potassium current (IK1) and expressing the hyperpolarization- activated current (If).	Potassium	178-187	IKAROS family zinc finger 1	Homo sapiens	197-200
30919496-5	2019	Values of Km , alpha, n, and Ks for the immobilized enzyme were calculated to be 1.25 x 10-2  microM, 0.56, 3.19, and 0.28 Sec-1 , respectively.	Potassium	29-31	secretory blood group 1, pseudogene	Homo sapiens	123-128
30919410-8	2019	Additionally, our results suggest that B. abortus-induced IL-1beta secretion depends on a P2X7-independent potassium efflux, lysosomal acidification, cathepsin release, mechanisms clearly associated to NLRP3 inflammasome.	Potassium	107-116	interleukin 1 beta	Mus musculus	58-66
30230667-3	2019	The advent of new therapeutics aimed at lowering serum potassium has raised the possibility of optimising potassium control to enable greater use of renin-angiotensin-aldosterone system inhibitors in the management of CKD.	Potassium	55-64	renin	Homo sapiens	149-154
30230667-3	2019	The advent of new therapeutics aimed at lowering serum potassium has raised the possibility of optimising potassium control to enable greater use of renin-angiotensin-aldosterone system inhibitors in the management of CKD.	Potassium	106-115	renin	Homo sapiens	149-154
31061103-4	2019	Here, we demonstrated that HY5 directly interacts with a Reduced Potassium Dependence3/Histone Deacetylase1 (HDA1)-type histone deacetylase, HDA15, both in vitro and in vivo.	Potassium	65-74	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	27-30
31061103-4	2019	Here, we demonstrated that HY5 directly interacts with a Reduced Potassium Dependence3/Histone Deacetylase1 (HDA1)-type histone deacetylase, HDA15, both in vitro and in vivo.	Potassium	65-74	histone deacetylase 1	Arabidopsis thaliana	75-107
31061103-4	2019	Here, we demonstrated that HY5 directly interacts with a Reduced Potassium Dependence3/Histone Deacetylase1 (HDA1)-type histone deacetylase, HDA15, both in vitro and in vivo.	Potassium	65-74	histone deacetylase 1	Arabidopsis thaliana	109-113
31061103-4	2019	Here, we demonstrated that HY5 directly interacts with a Reduced Potassium Dependence3/Histone Deacetylase1 (HDA1)-type histone deacetylase, HDA15, both in vitro and in vivo.	Potassium	65-74	histone deacetylase 15	Arabidopsis thaliana	141-146
31602841-16	2019	The activities of Na+-K+-ATPase and Ca2+-Mg2+-ATPase in liver of mice were significantly enhanced in each dose group( P&lt;0.	Potassium	18-23	dynein, axonemal, heavy chain 8	Mus musculus	25-31
31297160-6	2019	Results: The plastidial expression of the KS domain could complement the defective phenotypes of a KASI knockout mutant generated by CRISPR/Cas9.	Potassium	42-44	3-ketoacyl-acyl carrier protein synthase I	Arabidopsis thaliana	99-103
31221261-9	2019	Lower potassium was associated with longer QT intervals (-2.8 ms; 99.75% CI: -3.5 to -2.0), JT, QRS, and PR durations, but all potassium associations were driven by use of antihypertensive drugs.	Potassium	6-15	transmembrane protein 37	Homo sapiens	105-107
31212818-2	2019	In addition, the selective Kv2.1 channel blocker guangxitoxin (GxTx-1E) and MiDCA1 competitively inhibited the outward potassium current in DRG neurons.	Potassium	119-128	potassium voltage-gated channel subfamily B member 1	Homo sapiens	27-32
31174368-5	2019	Firstly, APP is shown to interact with and modulate the levels and activity of the neuron-specific Potassium-Chloride (K+-Cl-) cotransporter KCC2/SLC12A5.	Potassium	99-108	solute carrier family 12 member 5	Homo sapiens	146-153
30945454-4	2019	In this study, we revealed that potassium voltage-gated channel subfamily Q member 1 opposite strand 1 (KCNQ1OT1) was significantly upregulated in ischemic stroke.	Potassium	32-41	KCNQ1 overlapping transcript 1	Mus musculus	104-112
31028120-6	2019	At a cellular level, Dlg1 exhibited an indispensable function to maintain membrane potential changes by securing potassium ion (K+) efflux and subsequent calcium ion (Ca2+) influx events in DCs upon stimulation, both of which are known to be required for proper function of DCs.	Potassium	113-122	discs large MAGUK scaffold protein 1	Mus musculus	21-25
31016551-7	2019	Gating of P2X7 for 3 h significantly decreased intracellular ATP levels in living cells, but these had returned to normal by 20 h. P2X7-mediated ATP release was dependent on a rise in cytosolic calcium and the depletion of intracellular potassium, but was not blocked by inhibitors of pannexins or connexins.	Potassium	237-246	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	10-14
31016551-7	2019	Gating of P2X7 for 3 h significantly decreased intracellular ATP levels in living cells, but these had returned to normal by 20 h. P2X7-mediated ATP release was dependent on a rise in cytosolic calcium and the depletion of intracellular potassium, but was not blocked by inhibitors of pannexins or connexins.	Potassium	237-246	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	131-135
32884994-5	2020	In cells transiently transfected with ubiquitin (UB) constructs contained different lysine residues (Ks), Vps34 ubiquitination could occur regardless of the presence of any Ks in UB.	Potassium	101-103	phosphatidylinositol 3-kinase catalytic subunit type 3	Mus musculus	106-111
31236320-3	2019	For example, the KCNQ1-KCNE1 channel produces a slowly-activating potassium current, while KCNE3 makes KCNQ1 a voltage-independent, constitutively open channel.	Potassium	66-75	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	17-22
31236320-3	2019	For example, the KCNQ1-KCNE1 channel produces a slowly-activating potassium current, while KCNE3 makes KCNQ1 a voltage-independent, constitutively open channel.	Potassium	66-75	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	23-28
31236320-3	2019	For example, the KCNQ1-KCNE1 channel produces a slowly-activating potassium current, while KCNE3 makes KCNQ1 a voltage-independent, constitutively open channel.	Potassium	66-75	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	91-96
31236320-3	2019	For example, the KCNQ1-KCNE1 channel produces a slowly-activating potassium current, while KCNE3 makes KCNQ1 a voltage-independent, constitutively open channel.	Potassium	66-75	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	103-108
31092056-2	2019	It also, plays a significant role in the transport of calcium and potassium across the cell membranes and protects against cardiac arrhythmias and is useful for their treatment due to hypomagnesemia induced from the proton pump inhibitors (PPIs).	Potassium	66-75	ATPase H+/K+ transporting subunit alpha	Homo sapiens	216-227
30758905-3	2019	CONCLUSIONS: Photosynthetic bacteria and potassium-solubilizing bacteria inoculation significantly enhanced the expression of antioxidant enzyme-related genes and increased the activities of the antioxidant enzymes superoxide dismutase, catalase and ascorbate peroxidase.	Potassium	41-50	peroxidase 1	Zea mays	260-270
30910378-8	2019	We highlight GIPR, a potential diabetes drug target, as possibly implicated in the genetic control of urinary potassium excretion, and NRBP1, a locus associated with gout, as plausibly involved in sodium and albumin excretion.	Potassium	110-119	gastric inhibitory polypeptide receptor	Homo sapiens	13-17
30950624-0	2019	Potassium, Calcium, and Magnesium Bridging of AOT to Mica at Constant Ionic Strength.	Potassium	0-9	MHC class I polypeptide-related sequence A	Homo sapiens	53-57
30950624-2	2019	It was found that sodium ions did not show any bridging effect in this system; however, calcium, magnesium, and potassium all caused adsorption of the organic to the mica surface.	Potassium	112-121	MHC class I polypeptide-related sequence A	Homo sapiens	166-170
31017964-6	2019	The changes in protein expression were associated with ~50% decrease in hERG potassium conductance.	Potassium	77-86	ETS transcription factor ERG	Homo sapiens	72-76
30784151-1	2019	The first main-group element radical based one-dimensional magnetic chain (1K)n was realized by one-electron reduction of the pyridinyl functionalized borane 1 with elemental potassium in THF in the absence of 18-crown-6 (18-c-6).	Potassium	175-184	complement C6	Homo sapiens	225-228
30784151-4	2019	In contrast, the reduction in the presence of 18-c-6 afforded the separated radical anion salt 1K(Crown), in which the potassium cation was trapped by THF and 18-c-6 molecules.	Potassium	119-128	complement C6	Homo sapiens	49-52
30784151-4	2019	In contrast, the reduction in the presence of 18-c-6 afforded the separated radical anion salt 1K(Crown), in which the potassium cation was trapped by THF and 18-c-6 molecules.	Potassium	119-128	complement C6	Homo sapiens	162-165
30967508-1	2019	Membrane depolarization and intracellular Ca2+ promote activation of the large-conductance Ca2+- and voltage-gated (Slo1) big potassium (BK) channel.	Potassium	126-135	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	116-120
31013253-0	2019	Potassium acts through mTOR to regulate its own secretion.	Potassium	0-9	mechanistic target of rapamycin kinase	Homo sapiens	23-27
30918124-2	2019	The underlying channels are formed from tetramers of KCNQ1 along with one to four KCNE1 accessory subunits, but how these components together gate the I Ks complex to open the pore is controversial.	Potassium	153-155	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	53-58
30918124-2	2019	The underlying channels are formed from tetramers of KCNQ1 along with one to four KCNE1 accessory subunits, but how these components together gate the I Ks complex to open the pore is controversial.	Potassium	153-155	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	82-87
30689740-3	2019	The generally accepted common mechanism whereby drugs prolong QT is block of a key repolarizing potassium current in heart, IKr, generated by expression of KCNH2, also known as HERG.	Potassium	96-105	potassium voltage-gated channel subfamily H member 2	Homo sapiens	156-161
30689740-3	2019	The generally accepted common mechanism whereby drugs prolong QT is block of a key repolarizing potassium current in heart, IKr, generated by expression of KCNH2, also known as HERG.	Potassium	96-105	potassium voltage-gated channel subfamily H member 2	Homo sapiens	177-181
30816699-6	2019	For kappa-carrageenan in the presence of potassium, a disorder-order transition from random coil to single helix is first observed (secondary structure), followed by intrachain supercoiling events (tertiary structure) and macroscopic anisotropic domains which are parts of a network (quaternary structure) with tunable elasticity up to ~103 Pa.	Potassium	41-50	coilin	Homo sapiens	92-96
30835490-6	2019	We reproduced key electrophysiological and pharmacological features known for native IK1, including current enhancement by external potassium and voltage- and concentration-dependent blockade by external barium.	Potassium	132-141	IKAROS family zinc finger 1	Homo sapiens	85-88
31344212-1	2019	The renin-angiotensin-aldosterone system modulates volume, sodium and potassium homeostasis.	Potassium	70-79	renin	Homo sapiens	4-9
30909873-0	2019	Urinary angiotensinogen level is associated with potassium homeostasis and clinical outcome in patients with polycystic kidney disease: a prospective cohort study.	Potassium	49-58	angiotensinogen	Homo sapiens	8-23
30850693-2	2019	The structure of a putative G-quadruplex sequence (S1: GGAGAAGGAGGAGGTGGAGGAGGAGGG) in potassium solution in the her2 promoter has been resolved mainly through nuclear magnetic resonance (NMR) spectroscopy.	Potassium	87-96	erb-b2 receptor tyrosine kinase 2	Homo sapiens	113-117
30482581-8	2019	Awareness of this association between claudin 10 mutations and electrolyte abnormalities, namely hypokalemia and hypermagnesemia, sheds new light on the physiology of potassium and magnesium handling along the nephron and increases the likelihood of identifying the underlying tubular mechanism in patients with newly diagnosed hypokalemia with or without concomitant hypermagnesemia.	Potassium	167-176	claudin 10	Homo sapiens	38-48
30623727-4	2019	The alteration of basolateral potassium conductance is essential for the effect of dietary K+ intake on NCC because deletion of Kir4.1 in the DCT abolished the effect of dietary K+ intake on NCC.	Potassium	30-39	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	128-134
30623727-5	2019	Since potassium intake-mediated regulation of NCC plays a key role in regulating renal K+ excretion and potassium homeostasis, the deletion of Kir4.1 caused severe hypokalemia and metabolic alkalosis under control conditions and even during increased dietary K+ intake.	Potassium	6-15	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	143-149
30623727-5	2019	Since potassium intake-mediated regulation of NCC plays a key role in regulating renal K+ excretion and potassium homeostasis, the deletion of Kir4.1 caused severe hypokalemia and metabolic alkalosis under control conditions and even during increased dietary K+ intake.	Potassium	104-113	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	143-149
29083247-1	2019	The potassium ion, K+, a neuronal signal that is released during excitatory synaptic activity, produces acute activation of glucose consumption in cultured astrocytes, a phenomenon mediated by the sodium bicarbonate cotransporter NBCe1 ( SLC4A4).	Potassium	4-13	solute carrier family 4 (anion exchanger), member 4	Mus musculus	238-244
30731085-1	2019	Cardiac sodium (Na+) potassium ATPase (NaK) pumps, neuronal sodium channels (INa), and sodium calcium (Ca2+) exchangers (NCX1) may co-localize to form a Na+ microdomain.	Potassium	21-30	internexin neuronal intermediate filament protein alpha	Canis lupus familiaris	77-80
30731085-1	2019	Cardiac sodium (Na+) potassium ATPase (NaK) pumps, neuronal sodium channels (INa), and sodium calcium (Ca2+) exchangers (NCX1) may co-localize to form a Na+ microdomain.	Potassium	21-30	solute carrier family 8 member A1	Canis lupus familiaris	121-125
30556625-3	2019	The crown-ether complexes of sodium (1-Na) and potassium (1-K) exhibited different structures, with sodium preferring coordination to the nitrogen end, whereas potassium binds in an unusual eta2 -coordination mode to the two central carbon atoms.	Potassium	47-56	DNA polymerase iota	Homo sapiens	190-194
30556625-3	2019	The crown-ether complexes of sodium (1-Na) and potassium (1-K) exhibited different structures, with sodium preferring coordination to the nitrogen end, whereas potassium binds in an unusual eta2 -coordination mode to the two central carbon atoms.	Potassium	160-169	DNA polymerase iota	Homo sapiens	190-194
30787866-1	2019	Downstream Regulatory Element Antagonist Modulator (DREAM)/KChIP3/calsenilin is a neuronal calcium sensor (NCS) with multiple functions, including the regulation of A-type outward potassium currents (I A).	Potassium	180-189	potassium voltage-gated channel interacting protein 3	Rattus norvegicus	0-50
30787866-1	2019	Downstream Regulatory Element Antagonist Modulator (DREAM)/KChIP3/calsenilin is a neuronal calcium sensor (NCS) with multiple functions, including the regulation of A-type outward potassium currents (I A).	Potassium	180-189	potassium voltage-gated channel interacting protein 3	Rattus norvegicus	52-57
30787866-1	2019	Downstream Regulatory Element Antagonist Modulator (DREAM)/KChIP3/calsenilin is a neuronal calcium sensor (NCS) with multiple functions, including the regulation of A-type outward potassium currents (I A).	Potassium	180-189	potassium voltage-gated channel interacting protein 3	Rattus norvegicus	59-65
30787866-1	2019	Downstream Regulatory Element Antagonist Modulator (DREAM)/KChIP3/calsenilin is a neuronal calcium sensor (NCS) with multiple functions, including the regulation of A-type outward potassium currents (I A).	Potassium	180-189	potassium voltage-gated channel interacting protein 3	Rattus norvegicus	66-76
30520694-17	2019	Both hormones require PAK4 activation to stimulate sodium-potassium adenosine triphosphatase activity.	Potassium	58-67	p21 (RAC1) activated kinase 4	Rattus norvegicus	22-26
30604490-2	2019	Reactions of lithium or potassium salts of a variety of beta-diketiminates have given both three-coordinate complexes, [{HC(RCNAr)2 }BeX] (R=H or Me; Ar=Mes, Dep or Dip; X=Br or I); and four-coordinate systems, [{HC(MeCNPh)2 }BeBr(OEt2 )] and [{HC(MeCNDip)(MeCNC2 H4 NMe2 }BeI].	Potassium	24-33	brain expressed X-linked 3	Homo sapiens	133-136
30289750-2	2019	Human KCNE5 mutations are associated with atrial fibrillation (AF)- and Brugada syndrome (BrS)-induced cardiac arrhythmias that can arise from increased potassium current in cardiomyocytes.	Potassium	153-162	potassium voltage-gated channel subfamily E regulatory subunit 5	Homo sapiens	6-11
29447615-4	2019	In this work, we explored the structural role of potassium ions in Site 1 and Site 2 and how they affect the interactions of compounds with high affinities for HDAC1 (AC1OCG0B, Chlamydocin, Dacinostat and Quisinostat) and SAHA (a pan-inhibitor) using molecular docking and molecular dynamics (MD) simulations in concert with a Molecular-Mechanics-Generalized-Born-Surface-Area (MMGBSA) approach.	Potassium	49-58	histone deacetylase 1	Homo sapiens	160-165
30847194-2	2019	The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help to indicate this predisposition.	Potassium	75-77	forkhead box P3	Homo sapiens	42-47
30611209-0	2019	Inhibitory effect of ultrasonic stimulation on the voltage-dependent potassium currents in rat hippocampal CA1 neurons.	Potassium	69-78	carbonic anhydrase 1	Rattus norvegicus	107-110
30605673-0	2019	Inhibition of Hsp70 Suppresses Neuronal Hyperexcitability and Attenuates Epilepsy by Enhancing A-Type Potassium Current.	Potassium	102-111	heat shock protein family A (Hsp70) member 4	Homo sapiens	14-19
30605673-4	2019	Hsp70 expression is upregulated in a KA model of TLE, and silencing or inhibition of Hsp70 suppresses neuronal hyperexcitability and attenuates acute or chronic epilepsy by enhancing A-type potassium current in hippocampal neurons.	Potassium	190-199	heat shock protein family A (Hsp70) member 4	Homo sapiens	85-90
31583586-5	2019	NG2-glia contact synapses and respond to neurotransmitters and potassium released during neuronal transmission; to this end, NG2-glia (OPCs) express multiple neurotransmitter receptors and ion channels, with prominent roles being identified for glutamatergic signalling and potassium channels in oligodendrocyte differentiation.	Potassium	63-72	chondroitin sulfate proteoglycan 4	Homo sapiens	0-3
31583586-5	2019	NG2-glia contact synapses and respond to neurotransmitters and potassium released during neuronal transmission; to this end, NG2-glia (OPCs) express multiple neurotransmitter receptors and ion channels, with prominent roles being identified for glutamatergic signalling and potassium channels in oligodendrocyte differentiation.	Potassium	274-283	chondroitin sulfate proteoglycan 4	Homo sapiens	0-3
31583586-5	2019	NG2-glia contact synapses and respond to neurotransmitters and potassium released during neuronal transmission; to this end, NG2-glia (OPCs) express multiple neurotransmitter receptors and ion channels, with prominent roles being identified for glutamatergic signalling and potassium channels in oligodendrocyte differentiation.	Potassium	274-283	chondroitin sulfate proteoglycan 4	Homo sapiens	125-128
30089030-2	2019	NCC activity is critical for modulation of arterial blood pressure and serum potassium levels.	Potassium	77-86	solute carrier family 12, member 3	Mus musculus	0-3
31114435-10	2019	In the subgroup of children with normal bladder capacity a trend towards a positive correlation between copeptin and potassium was found.	Potassium	117-126	arginine vasopressin	Homo sapiens	104-112
31114435-12	2019	The relation between potassium and copeptin levels and the clinical significance of the relation require further studies.	Potassium	21-30	arginine vasopressin	Homo sapiens	35-43
31854954-1	2019	Kv1.3 is a voltage gated potassium channel located in the plasma membrane, as well as at intracellular levels, such as mitochondria (mitoKv1.3), nucleus and Golgi apparatus.	Potassium	25-34	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	0-5
30306852-6	2019	More specifically, GSK-3beta-sensitive cellular transport regulation involves various calcium, chloride, sodium, and potassium ion channels, as well as a number of Na+-coupled cellular carriers including excitatory amino acid transporters EAAT2, 3 and 4, high-affinity Na+ coupled glucose carriers SGLT1, creatine transporter 1 CreaT1, and the type II sodium/phosphate cotransporter NaPi-IIa.	Potassium	117-126	glycogen synthase kinase 3 alpha	Homo sapiens	19-28
29588531-2	2019	Kidney dysfunction and renin-angiotensin-aldosterone system inhibiting drugs are notorious for their tendency to induce hyperkalemia by decreasing the excretion of potassium.	Potassium	164-173	renin	Homo sapiens	23-28
30391945-4	2019	Using inhibitor-based approaches, we show that NLRP3 activation by T. vaginalis involves host cell detection of extracellular ATP via P2X7 receptors and potassium efflux.	Potassium	153-162	NLR family pyrin domain containing 3	Homo sapiens	47-52
30348896-8	2019	Glutamate, potassium, and DL-threo-beta-benzyloxyaspartate facilitated crosslinking in the A243C/T396C transporter and this suggests that the TM4b-4c loop and beta-bridge region in TM7 were drawn into close proximity to each other in the inward- and outward-facing conformation of EAAT1.	Potassium	11-20	tetraspanin 16	Homo sapiens	142-146
30348896-8	2019	Glutamate, potassium, and DL-threo-beta-benzyloxyaspartate facilitated crosslinking in the A243C/T396C transporter and this suggests that the TM4b-4c loop and beta-bridge region in TM7 were drawn into close proximity to each other in the inward- and outward-facing conformation of EAAT1.	Potassium	11-20	solute carrier family 1 member 3	Homo sapiens	281-286
29982819-2	2019	Aldosterone stimulates the collecting duct mineralocorticoid receptor (MR) to upregulate the epithelial sodium channel (ENaC) and stimulate electrogenic sodium reabsorption, with secretion of potassium and protons.	Potassium	192-201	nuclear receptor subfamily 3 group C member 2	Homo sapiens	43-69
29982819-2	2019	Aldosterone stimulates the collecting duct mineralocorticoid receptor (MR) to upregulate the epithelial sodium channel (ENaC) and stimulate electrogenic sodium reabsorption, with secretion of potassium and protons.	Potassium	192-201	nuclear receptor subfamily 3 group C member 2	Homo sapiens	71-73
30540522-2	2019	Recently, we have shown that potassium influx through a potassium channel complex AKT1-KC1 is inhibited by cesium in Arabidopsis thaliana and the resultant reduction in potassium accumulation in the plant is the primary cause of retarded growth.	Potassium	29-38	K+ transporter 1	Arabidopsis thaliana	82-86
30540522-2	2019	Recently, we have shown that potassium influx through a potassium channel complex AKT1-KC1 is inhibited by cesium in Arabidopsis thaliana and the resultant reduction in potassium accumulation in the plant is the primary cause of retarded growth.	Potassium	29-38	potassium channel protein	Arabidopsis thaliana	87-90
30540522-2	2019	Recently, we have shown that potassium influx through a potassium channel complex AKT1-KC1 is inhibited by cesium in Arabidopsis thaliana and the resultant reduction in potassium accumulation in the plant is the primary cause of retarded growth.	Potassium	56-65	K+ transporter 1	Arabidopsis thaliana	82-86
30540522-2	2019	Recently, we have shown that potassium influx through a potassium channel complex AKT1-KC1 is inhibited by cesium in Arabidopsis thaliana and the resultant reduction in potassium accumulation in the plant is the primary cause of retarded growth.	Potassium	56-65	potassium channel protein	Arabidopsis thaliana	87-90
30540522-3	2019	By contrast, a major potassium transporter, HAK5 whose function is crucial under potassium deficiency, was found to be either not affected or complementary under cesium stress in the low affinity potassium range.	Potassium	21-30	high affinity K+ transporter 5	Arabidopsis thaliana	44-48
30540522-3	2019	By contrast, a major potassium transporter, HAK5 whose function is crucial under potassium deficiency, was found to be either not affected or complementary under cesium stress in the low affinity potassium range.	Potassium	81-90	high affinity K+ transporter 5	Arabidopsis thaliana	44-48
30412386-8	2018	Kinetic analyses using recombinant proteins revealed that CYP2C9 variants (A82V and H344R) showed substantially lower  Ks values than the wild type, although CYP1A1 variant (V382I) showed kinetic parameters similar to the wild type.	Potassium	119-121	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	58-64
30532259-7	2018	The crystal structure of the HDAC3:SMRT complex possesses two monovalent cations (MVCs) labeled as potassium with one MVC binding site near the active site Zn(II) and the second MVC binding site &gt;=20 A from the active site Zn(II).	Potassium	99-108	histone deacetylase 3	Apis mellifera	29-34
30532259-9	2018	We also report the effects of varying concentrations of potassium ions where [K+] up to 10 mM increase HDAC3 activity with a maximum kcat/KM of approximately 80,000 M-1s-1 while [K+] above 10 mM inhibit HDAC3 activity.	Potassium	56-65	histone deacetylase 3	Apis mellifera	103-108
30532259-9	2018	We also report the effects of varying concentrations of potassium ions where [K+] up to 10 mM increase HDAC3 activity with a maximum kcat/KM of approximately 80,000 M-1s-1 while [K+] above 10 mM inhibit HDAC3 activity.	Potassium	56-65	histone deacetylase 3	Apis mellifera	203-208
30532259-11	2018	The regulatory effects of zinc, potassium, and 10-HDA concentration on HDAC3 activity suggest a strong correlation between these chemical species and epigenetic control over Apis mellifera caste differentiation among other control mechanisms.	Potassium	32-41	histone deacetylase 3	Apis mellifera	71-76
30517856-4	2018	We show that dietary potassium restriction leads promptly to proliferation of various nephron segments, including the distal convoluted tubule, whereas disruption of the potassium sensor Kir4.1 causes atrophy, despite ambient hypokalemia.	Potassium	170-179	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	187-193
30266221-5	2018	Based on isotopic measurements, Edelman showed SNa level to be a function of exchangeable sodium and potassium divided by total-body water.	Potassium	101-110	snail family transcriptional repressor 1	Homo sapiens	47-50
30096351-8	2018	Moreover, NLRP1 but not NLRP3 was required for inflammasome activation in response to nigericin, a potassium ionophore and well-established NLRP3 activator in immune cells.	Potassium	99-108	NLR family pyrin domain containing 1	Homo sapiens	10-15
30109784-7	2018	Compared with the control group, Ca-PS treatment significantly reduced serum potassium levels (P &lt;0.01).	Potassium	77-86	calcyphosine	Homo sapiens	33-38
30109784-8	2018	More patients in the Ca-PS group had lower serum potassium levels than the safety level of &lt;5.5 mmol/L (32% for control vs. 61% for Ca-PS, P &lt;0.01).	Potassium	49-58	calcyphosine	Homo sapiens	21-26
30109784-11	2018	Ca-PS treatment decreases serum levels of potassium and phosphorus in MHD patients with interdialytic hyperkalemia.	Potassium	42-51	calcyphosine	Homo sapiens	0-5
30441852-15	2018	Cardiac targeting peptide appears to utilize Kcnh5 to gain cell entry, a phenomenon that is affected by pre-treatment with Quinidine and changes in potassium levels.	Potassium	148-157	potassium voltage-gated channel subfamily H member 5	Homo sapiens	45-50
30473666-2	2018	Our lab has recently explored this sub-cellular microdomain and found that potassium inward rectifier Kir2.x is found in association with caveolin-3.	Potassium	75-84	caveolin 3	Homo sapiens	138-148
30110571-0	2018	Potassium conservation is impaired in mice with reduced renal expression of Kir4.1.	Potassium	0-9	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	76-82
30107592-4	2018	Here, we expanded the mutation spectrum of KMT2D and KDM6A in KS by identifying 37 new KMT2D sequence variants.	Potassium	62-64	lysine methyltransferase 2D	Homo sapiens	43-48
30107592-4	2018	Here, we expanded the mutation spectrum of KMT2D and KDM6A in KS by identifying 37 new KMT2D sequence variants.	Potassium	62-64	lysine demethylase 6A	Homo sapiens	53-58
30107592-4	2018	Here, we expanded the mutation spectrum of KMT2D and KDM6A in KS by identifying 37 new KMT2D sequence variants.	Potassium	62-64	lysine methyltransferase 2D	Homo sapiens	87-92
30160358-10	2018	Co-expression of KCND3/WT and SCN1Bbeta/S248R or SCN1Bbeta/R250T increased the transient outward potassium current Ito by 27.44% and 199.89%, respectively (P &lt; 0.05 and P &lt; 0.01, respectively) when compared with SCN1Bbeta/WT.	Potassium	97-106	potassium voltage-gated channel subfamily D member 3	Homo sapiens	17-22
29582401-2	2018	TRPV4 is now recognized as a polymodal ionotropic receptor: it is a broadly expressed, nonselective cation channel (permeable to calcium, potassium, magnesium, and sodium) that plays an important role in a multitude of physiological processes.	Potassium	138-147	transient receptor potential cation channel subfamily V member 4	Homo sapiens	0-5
30296052-2	2018	To address these limitations, we developed a novel kappa-carrageenan/polyacrylamide (KC/PAM) DN hydrogel through a dual physical-cross-linking strategy, with the ductile, hydrophobically associated PAM being the first network, and the rigid potassium ion (K+) cross-linked KC being the second network.	Potassium	241-250	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	198-201
30380640-9	2018	However, administration of aloin suppressed liver injury as well as Muller cell swelling through the normalization of Kir4.1 and aquaporin-4 channels, which play a key role in potassium and water transport in Muller cells.	Potassium	176-185	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	118-124
30380640-9	2018	However, administration of aloin suppressed liver injury as well as Muller cell swelling through the normalization of Kir4.1 and aquaporin-4 channels, which play a key role in potassium and water transport in Muller cells.	Potassium	176-185	aquaporin 4	Rattus norvegicus	129-140
30341287-3	2018	We here demonstrate that the neurokinin substance-P (Sub-P) activates a neurokinin-3 receptor (NK-3R) in rabbit, prolonging action potential (AP) duration through inhibition of a background potassium current.	Potassium	190-199	neuromedin-K receptor	Oryctolagus cuniculus	72-93
30341287-3	2018	We here demonstrate that the neurokinin substance-P (Sub-P) activates a neurokinin-3 receptor (NK-3R) in rabbit, prolonging action potential (AP) duration through inhibition of a background potassium current.	Potassium	190-199	neuromedin-K receptor	Oryctolagus cuniculus	95-100
29902467-0	2018	Correcting deregulated Fxyd1 expression rescues deficits in neuronal arborization and potassium homeostasis in MeCP2 deficient male mice.	Potassium	86-95	FXYD domain-containing ion transport regulator 1	Mus musculus	23-28
29902467-6	2018	Deletion of one Fxyd1 allele also prevented the increased extracellular potassium (K+) accumulation observed in cerebro-cortical neurons from Mecp2 KO animals in response to the NKA inhibitor ouabain, and rescued the loss of dendritic arborization observed in FC neurons of Mecp2 KO mice.	Potassium	72-81	FXYD domain-containing ion transport regulator 1	Mus musculus	16-21
29902467-6	2018	Deletion of one Fxyd1 allele also prevented the increased extracellular potassium (K+) accumulation observed in cerebro-cortical neurons from Mecp2 KO animals in response to the NKA inhibitor ouabain, and rescued the loss of dendritic arborization observed in FC neurons of Mecp2 KO mice.	Potassium	72-81	methyl CpG binding protein 2	Mus musculus	142-147
30199632-3	2018	These can be significant in large systems, so to account for them we test a simple correction to XSAPT(KS)+ aiD, where "KS" indicates the use of Kohn-Sham orbitals.	Potassium	120-122	activation induced cytidine deaminase	Homo sapiens	108-111
30199632-6	2018	With the nonadditive dispersion correction, XSAPT(KS)+ aiD affords errors of ~1 kcal/mol for isomers of F-(H2O)10 and (H2O)20, where the benchmarks are complete-basis CCSD(T) energies, as well as for ion-water clusters X(H2O) n where n &lt;= 6 and X = F-, Cl-, SO42-, Li+, Na+, or K+.	Potassium	50-52	activation induced cytidine deaminase	Homo sapiens	55-58
29923766-4	2018	Chloride regulates WNK kinases in vitro by binding to the active site and inhibiting autophosphorylation and has been proposed to modulate WNK activity in the distal convoluted tubule in response to low dietary potassium.	Potassium	211-220	Wnk kinase	Drosophila melanogaster	19-22
30176543-1	2018	BACKGROUND: To determine if variations exist in the KSHV host receptor EPHA2"s coding region that affect KSHV infectivity and/or KS prevalence among South African HIV-infected patients.	Potassium	52-54	EPH receptor A2	Homo sapiens	71-76
30176543-5	2018	Aggregate variation across the entire EPHA2 coding region identified an association with KS (OR = 6.6 (95% CI 2.8, 15.9), p = 2.2 x 10-5).	Potassium	89-91	EPH receptor A2	Homo sapiens	38-43
30176543-11	2018	CONCLUSIONS: Variations in the KSHV entry receptor gene EPHA2 affected susceptibility to KSHV infection and KS development in a South African HIV-infected patient cohort.	Potassium	31-33	EPH receptor A2	Homo sapiens	56-61
29982385-0	2018	New potassium binders reduce the risk of hyperkalaemia in patients treated with renin-angiotensin-aldosterone system inhibitors.	Potassium	4-13	renin	Homo sapiens	80-85
30106427-7	2018	The meta-analysis revealed that the animals given C-peptide had lower glomerular volumes and lower urine potassium levels than the groups not given C-peptide.	Potassium	105-114	insulin	Homo sapiens	50-59
30106427-9	2018	However, the meta-analysis showed that the animals given C-peptide had lower glomerular volumes and lower urine potassium levels.	Potassium	112-121	insulin	Homo sapiens	57-66
30262858-4	2018	Several naturally occurring potassium ionophores (e.g. salinomycin) were shown to inhibit P-gp effectively.	Potassium	28-37	phosphoglycolate phosphatase	Homo sapiens	90-94
30271488-9	2018	In the multivariate Cox model, the extent of vascular invasion, tumour count, fibrinogen, HBV DNA load and serum potassium significantly affected prognosis.	Potassium	113-122	cytochrome c oxidase subunit 8A	Homo sapiens	20-23
29719168-5	2018	The Panx1 channel activated by various physiological stimuli or by increased concentrations of extracellular potassium ions has a large conductance (~500 pS, however, with multiple, long-lasting subconductance states) and is nonselectively permeable to small molecules, including ATP.	Potassium	109-118	pannexin 1	Homo sapiens	4-9
29846116-10	2018	Together, these observations suggest that WNK4 becomes active in the presence of KS-WNK1, despite a constant [Cl-]i.	Potassium	81-83	WNK lysine deficient protein kinase 4	Homo sapiens	42-46
29846116-10	2018	Together, these observations suggest that WNK4 becomes active in the presence of KS-WNK1, despite a constant [Cl-]i.	Potassium	81-83	WNK lysine deficient protein kinase 1	Homo sapiens	84-88
29719087-0	2018	Regulation of inward rectifier potassium current ionic channel remodeling by AT1 -Calcineurin-NFAT signaling pathway in stretch-induced hypertrophic atrial myocytes.	Potassium	31-40	nuclear factor of activated T-cells 5	Rattus norvegicus	94-98
30234232-4	2018	Hyperkalaemia is also indirectly associated with the progression of CKD; in fact higher serum potassium levels may lead to withdrawal of renin-angiotensin-system inhibiting drugs that currently represent the most effective tools to postpone ESRD.	Potassium	94-103	renin	Homo sapiens	137-142
29725771-7	2018	Serum potassium concentration (X +- SD) was higher in SLC4A1 group (3.66 +- 0.44 mEq/L) than in ATP6V0A4 group (2.96 +- 0.63 mEq/L) (p = 0.046).	Potassium	6-15	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	54-60
30169531-0	2018	KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts.	Potassium	66-75	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	0-6
30283826-8	2018	Patients with somatic KCNJ5 mutations required more potassium supplementation and had adrenal histology compatible with zona fasciculata-like cells compared with patients without the mutations (all P &lt; 0.05).	Potassium	52-61	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	22-27
30111140-2	2018	Due to the underlying symmetry of the potassium ions on the mica surface, the contact layers prefer to adopt an incommensurate square or rhombic symmetry.	Potassium	38-47	MHC class I polypeptide-related sequence A	Homo sapiens	60-64
30097648-0	2018	Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism.	Potassium	45-54	adenosine kinase	Mus musculus	0-16
30078841-6	2018	In particular, the S. mutans-induced NLRP3 inflammasome was mediated by adenosine triphosphate (ATP) release, potassium depletion and lysosomal damage.	Potassium	110-119	NLR family pyrin domain containing 3	Homo sapiens	37-42
30127740-1	2018	Inwardly rectifying potassium (Kir) channel subunits Kir4.1 are specifically expressed in astrocytes and regulate neuronal excitability by mediating spatial potassium buffering.	Potassium	20-29	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	53-59
30082733-1	2018	We recently reported the reduced ATP-sensitive potassium (KATP) channel activities in the transgenic mouse heart overexpressing the vascular type KATP channel pore-forming subunit (Kir6.1).	Potassium	47-56	potassium inwardly-rectifying channel, subfamily J, member 8	Mus musculus	181-187
29476442-1	2018	Mutations in KCNJ10, which encodes the inwardly rectifying potassium channel Kir4.1, a primary regulator of membrane excitability and potassium homeostasis, cause a complex syndrome characterized by seizures, sensorineural deafness, ataxia, intellectual disability, and electrolyte imbalance called SeSAME/EAST syndrome.	Potassium	59-68	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	13-19
30180643-2	2018	Mica muscovite is a particularly interesting material, because there exist fossil and experimental evidence for nonlinear excitations transporting localized energy and charge along the cation rows within the potassium layers.	Potassium	208-217	MHC class I polypeptide-related sequence A	Homo sapiens	0-4
29617054-0	2018	Activation of voltage-gated sodium current and inhibition of erg-mediated potassium current caused by telmisartan, an antagonist of angiotensin II type-1 receptor, in HL-1 atrial cardiomyocytes.	Potassium	74-83	ETS transcription factor ERG	Homo sapiens	61-64
29330622-1	2018	Crop available soil potassium is generally low and on the decline in the southeastern states of the USA because of the increasing crop and runoff removal and decreasing application of potassium fertilizer.	Potassium	20-29	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	0-4
29330622-1	2018	Crop available soil potassium is generally low and on the decline in the southeastern states of the USA because of the increasing crop and runoff removal and decreasing application of potassium fertilizer.	Potassium	20-29	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	130-134
29330622-1	2018	Crop available soil potassium is generally low and on the decline in the southeastern states of the USA because of the increasing crop and runoff removal and decreasing application of potassium fertilizer.	Potassium	184-193	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	0-4
29745804-14	2018	The beta2 agonist salbutamol lowered potassium during exercise and late recovery but not during early postexercise, suggesting a protective effect against severe hypokalemia.	Potassium	37-46	ATPase H+ transporting V0 subunit a2	Homo sapiens	4-9
29694931-2	2018	This study assessed whether urinary potassium excretion is related to simultaneously calculated creatinine clearance (CrCl) and can predict AKI in the critically ill. MATERIALS AND METHODS: In this prospective cohort study, the correlation between 2-h urinary potassium excretion and simultaneously calculated CrCl of 61 critically ill patients was assessed by Pearson"s correlation coefficient, and their ability to predict AKI (&gt;=stage 1 KDIGO) in the subsequent 7 days was assessed by area under the receiver-operating-characteristic (AUROC) curve.	Potassium	36-45	CRCL	Homo sapiens	118-122
29694931-2	2018	This study assessed whether urinary potassium excretion is related to simultaneously calculated creatinine clearance (CrCl) and can predict AKI in the critically ill. MATERIALS AND METHODS: In this prospective cohort study, the correlation between 2-h urinary potassium excretion and simultaneously calculated CrCl of 61 critically ill patients was assessed by Pearson"s correlation coefficient, and their ability to predict AKI (&gt;=stage 1 KDIGO) in the subsequent 7 days was assessed by area under the receiver-operating-characteristic (AUROC) curve.	Potassium	36-45	CRCL	Homo sapiens	310-314
29694931-4	2018	CONCLUSIONS: Urinary potassium excretion correlates with CrCl and predicts AKI in the critically ill without recent furosemide exposure.	Potassium	21-30	CRCL	Homo sapiens	57-61
29603743-4	2018	In the present study, inhibiting NO, PGs, Na+ /K+ -ATPase and inwardly rectifying potassium (KIR ) channels did not blunt augmented hyperaemia during hypoxic exercise beyond previous observations with NO/PG block alone.	Potassium	82-91	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	93-96
29603743-9	2018	We hypothesized that combined inhibition of NO, PGs, Na+ /K+ -ATPase and inwardly rectifying potassium (KIR ) channels would abolish the augmented hyperaemic response in HypEx.	Potassium	93-102	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	104-107
29791245-5	2018	The accumulation of potassium and other cations in PI(3,5)P2-deficient yeast is relieved by mutations that inactivate Vnx1 or inactivate the V-ATPase and by mutations that increase the activity of a vacuolar cation export channel, Yvc1.	Potassium	20-29	Vnx1p	Saccharomyces cerevisiae S288C	118-122
20301512-10	1993	DIAGNOSIS/TESTING: The diagnosis of HOKPP is based on a history of episodes of flaccid paralysis with rapid installation and spontaneous recovery; low serum concentration of potassium (0.9 to 3.0 mmol/L) during attacks, but not between attacks; the identification of typical precipitating factors (i.e., rest after a strong physical exertion, prolonged immobility); and a family history consistent with autosomal dominant inheritance.	Potassium	174-183	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	36-41
32026957-4	2018	A potassium concentration after recovery from VT was 6.4 mEq/L, which was normalized by the administration of calcium gluconate, furosemide, and insulin with glucose.	Potassium	2-11	insulin	Homo sapiens	145-152
29767755-0	2018	A protein phosphatase 2C, AP2C1, interacts with and negatively regulates the function of CIPK9 under potassium-deficient conditions in Arabidopsis.	Potassium	101-110	Protein phosphatase 2C family protein	Arabidopsis thaliana	26-31
29767755-0	2018	A protein phosphatase 2C, AP2C1, interacts with and negatively regulates the function of CIPK9 under potassium-deficient conditions in Arabidopsis.	Potassium	101-110	CBL-interacting protein kinase 9	Arabidopsis thaliana	89-94
29958799-1	2018	Potassium (K+) efflux across the plasma membrane is thought to be an essential mechanism for ATP-induced NLRP3 inflammasome activation, yet the identity of the efflux channel has remained elusive.	Potassium	0-9	NLR family, pyrin domain containing 3	Mus musculus	105-110
29791245-5	2018	The accumulation of potassium and other cations in PI(3,5)P2-deficient yeast is relieved by mutations that inactivate Vnx1 or inactivate the V-ATPase and by mutations that increase the activity of a vacuolar cation export channel, Yvc1.	Potassium	20-29	Yvc1p	Saccharomyces cerevisiae S288C	231-235
29784874-4	2018	Kir2.1 maintains potassium homeostasis in heart muscle cells, and Kir2.1 defects lead to human disease.	Potassium	17-26	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	0-6
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	Ldb19p	Saccharomyces cerevisiae S288C	32-37
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	Ldb19p	Saccharomyces cerevisiae S288C	38-42
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	Aly1p	Saccharomyces cerevisiae S288C	44-48
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	Aly1p	Saccharomyces cerevisiae S288C	49-53
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	Aly2p	Saccharomyces cerevisiae S288C	59-63
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	Aly2p	Saccharomyces cerevisiae S288C	64-68
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	109-115
29784874-6	2018	Specifically, we found that the Ldb19/Art1, Aly1/Art6, and Aly2/Art3 alpha-arrestin adaptor proteins promote Kir2.1 trafficking to the cell surface, increase Kir2.1 activity at the plasma membrane, and raise intracellular potassium levels.	Potassium	222-231	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	158-164
29961781-4	2018	Our results demonstrate the key role of the structure of the mica surfaces, specifically the positions of potassium (K+) ions, in determining the nature of sliding friction with monolayer lubricants, including the presence or absence of stick-slip dynamics.	Potassium	106-115	MHC class I polypeptide-related sequence A	Homo sapiens	61-65
30271961-2	2018	Here, we report the role of Kir4.1 channels in NG2-glia during brain development, potassium signaling, and in an ischemic stroke disease model.	Potassium	82-91	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	28-34
30018331-5	2018	By targeting both the MHC class I complex (beta-2-microglobulin) and a broadly expressed sodium-potassium ATPase-subunit (CD298) with platinum-conjugated antibodies, human immune cells, stem cells as well as tumor cells could be multiplexed in the same single-cell assay.	Potassium	96-105	ATPase Na+/K+ transporting subunit beta 3	Homo sapiens	122-127
29661658-0	2018	Is Transcellular Potassium Shifting With Insulin, Albuterol, or Sodium Bicarbonate in Emergency Department Patients With Hyperkalemia Associated With Recurrent Hyperkalemia After Dialysis?	Potassium	17-26	insulin	Homo sapiens	41-48
29859980-2	2018	Slack activity is enhanced by interaction with the Fragile-X-Mental-Retardation-Protein (FMRP) and loss of FMRP leads to decreased sodium-activated potassium currents in medial nucleus of the trapezoid body neurons of the Fmr1-knockout (KO) mouse representing a mouse model of the human Fragile-X-Syndrome (FXS) and autism.	Potassium	148-157	potassium channel, subfamily T, member 1	Mus musculus	0-5
29859980-2	2018	Slack activity is enhanced by interaction with the Fragile-X-Mental-Retardation-Protein (FMRP) and loss of FMRP leads to decreased sodium-activated potassium currents in medial nucleus of the trapezoid body neurons of the Fmr1-knockout (KO) mouse representing a mouse model of the human Fragile-X-Syndrome (FXS) and autism.	Potassium	148-157	fragile X messenger ribonucleoprotein 1	Mus musculus	89-93
29859980-2	2018	Slack activity is enhanced by interaction with the Fragile-X-Mental-Retardation-Protein (FMRP) and loss of FMRP leads to decreased sodium-activated potassium currents in medial nucleus of the trapezoid body neurons of the Fmr1-knockout (KO) mouse representing a mouse model of the human Fragile-X-Syndrome (FXS) and autism.	Potassium	148-157	fragile X messenger ribonucleoprotein 1	Mus musculus	107-111
29859980-2	2018	Slack activity is enhanced by interaction with the Fragile-X-Mental-Retardation-Protein (FMRP) and loss of FMRP leads to decreased sodium-activated potassium currents in medial nucleus of the trapezoid body neurons of the Fmr1-knockout (KO) mouse representing a mouse model of the human Fragile-X-Syndrome (FXS) and autism.	Potassium	148-157	fragile X messenger ribonucleoprotein 1	Mus musculus	222-226
29962164-7	2018	The order of importance was phosphatase activity &gt; pH &gt; sucrase activity &gt; catalase activity &gt; total N &gt; available P &gt; available K &gt; soil moisture content &gt; urease activity &gt; electrical conductivity (EC); phosphatase activity, pH value, invertase activity, catalase activity, total nitrogen, available phosphorus, and available potassium showed significant correlation with SOC and SIC (P&lt;0.01).	Potassium	355-364	catalase isozyme 1-like	Gossypium hirsutum	84-92
29726949-12	2018	Serum potassium but not urinary free cortisol correlated with pNKCC2, pNCC, and Na+-Cl- cotransporter (NCC) in uEVs.	Potassium	6-15	solute carrier family 12 member 3	Homo sapiens	80-101
29726949-12	2018	Serum potassium but not urinary free cortisol correlated with pNKCC2, pNCC, and Na+-Cl- cotransporter (NCC) in uEVs.	Potassium	6-15	solute carrier family 12 member 3	Homo sapiens	71-74
29726949-15	2018	Potassium has recently been identified as an important driver of NCC activity, and low serum potassium may also contribute to increased renal sodium reabsorption and hypertension in CS.	Potassium	0-9	solute carrier family 12 member 3	Homo sapiens	65-68
29703946-1	2018	Potassium channel Kv2.1 regulates potassium current in cortical neurons and potassium efflux is necessary for cell apoptosis.	Potassium	34-43	potassium voltage-gated channel subfamily B member 1	Homo sapiens	18-23
29703946-1	2018	Potassium channel Kv2.1 regulates potassium current in cortical neurons and potassium efflux is necessary for cell apoptosis.	Potassium	76-85	potassium voltage-gated channel subfamily B member 1	Homo sapiens	18-23
29703946-7	2018	Our study suggests that BACE2 plays a neuroprotective role by cleavage of Kv2.1 to prevent the outward potassium currents, a potential new target for Alzheimer"s treatment.	Potassium	103-112	beta-secretase 2	Homo sapiens	24-29
29703946-7	2018	Our study suggests that BACE2 plays a neuroprotective role by cleavage of Kv2.1 to prevent the outward potassium currents, a potential new target for Alzheimer"s treatment.	Potassium	103-112	potassium voltage-gated channel subfamily B member 1	Homo sapiens	74-79
29953543-1	2018	KCa3.1 (also known as SK4 or IK1) is a mammalian intermediate-conductance potassium channel that plays a critical role in the activation of T cells, B cells, and mast cells, effluxing potassium ions to maintain a negative membrane potential for influxing calcium ions.	Potassium	74-83	potassium calcium-activated channel subfamily N member 4	Homo sapiens	0-6
29953543-1	2018	KCa3.1 (also known as SK4 or IK1) is a mammalian intermediate-conductance potassium channel that plays a critical role in the activation of T cells, B cells, and mast cells, effluxing potassium ions to maintain a negative membrane potential for influxing calcium ions.	Potassium	74-83	potassium calcium-activated channel subfamily N member 4	Homo sapiens	22-25
29953543-1	2018	KCa3.1 (also known as SK4 or IK1) is a mammalian intermediate-conductance potassium channel that plays a critical role in the activation of T cells, B cells, and mast cells, effluxing potassium ions to maintain a negative membrane potential for influxing calcium ions.	Potassium	74-83	potassium calcium-activated channel subfamily N member 4	Homo sapiens	29-32
29988564-1	2018	Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single skeletal muscle fibers; this calcium increase would couple muscle fiber excitation to an increase in metabolic output from mitochondria (excitation-metabolism coupling).	Potassium	199-208	ryanodine receptor 1	Homo sapiens	57-61
29988564-1	2018	Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single skeletal muscle fibers; this calcium increase would couple muscle fiber excitation to an increase in metabolic output from mitochondria (excitation-metabolism coupling).	Potassium	199-208	inositol 1,4,5-trisphosphate receptor type 3	Homo sapiens	67-79
29988564-1	2018	Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single skeletal muscle fibers; this calcium increase would couple muscle fiber excitation to an increase in metabolic output from mitochondria (excitation-metabolism coupling).	Potassium	199-208	inositol 1,4,5-trisphosphate receptor type 3	Homo sapiens	81-85
29549164-4	2018	The promalignant nature of Kir2.1 in gastric cancer cells was independent of potassium permeation but relied on its interaction with serine/threonine-protein kinase 38 (Stk38) to inhibit ubiquitination and degradation of mitogen-activated protein kinase kinase kinase 2 (MEKK2).	Potassium	77-86	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	27-33
29928032-1	2018	Two-pore domain potassium channels (K2P) constitute major candidates for the regulation of background potassium currents in mammalian cells.	Potassium	16-25	keratin 76	Homo sapiens	36-39
29481897-10	2018	The equivalent reduction in potassium current in the WT neurons following application of the appropriate amount of DTX-kappa reproduced the enhanced firing abilities of KO neurons, suggesting the Kv1.1 channel as a critical contributor to the hyperexcitability of KO neurons.	Potassium	28-37	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	196-201
30245542-7	2018	The fitted value of Ks =1.01 x 10-3 m min-1 at the Torrance drywell was consistent with the sandy soil texture at this site and the default value for sand in the HYDRUS soil catalog.	Potassium	20-22	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
30245542-8	2018	The drywell with this Ks = 1.01 x 10-3 m min-1 could easily infiltrate predicted surface runoff from a design rain event (~51.3 m3) within 5760 min (4 d).	Potassium	22-24	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
30245542-9	2018	In contrast, the fitted value of Ks=2.25 x 10-6 m min-1 at Fort Irwin was very low compared to the Torrance drywell and more than an order of magnitude smaller than the default value reported in the HYDRUS soil catalog for sandy clay loam at this site, likely due to clogging.	Potassium	33-35	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
29942493-6	2018	Patients with CLCNKB mutations had the lowest serum potassium and serum magnesium and the highest serum bicarbonate levels.	Potassium	52-61	chloride voltage-gated channel Kb	Homo sapiens	14-20
29523497-14	2018	Elevated serum creatinine (OR 1 3; p=0 046), aspartate aminotransferase (OR 1 5; p=0 075), and potassium (OR 3 6; p=0 0024) were independent predictors of death.	Potassium	95-104	olfactory receptor family 7 subfamily E member 22 pseudogene	Homo sapiens	106-112
29696970-3	2018	It was shown that the chiral center at C-4 plays a crucial role in controlling desymmetrization of the cyclopropenyl moiety, instigated by a profound potassium-templated effect.	Potassium	150-159	complement C4A (Rodgers blood group)	Homo sapiens	39-42
29499411-0	2018	GIRK1-mediated inwardly rectifying potassium current suppresses the epileptiform burst activities and the potential antiepileptic effect of ML297.	Potassium	35-44	potassium inwardly-rectifying channel, subfamily J, member 3	Mus musculus	0-5
29524437-5	2018	We showed that the orthosteric mGluR2 agonist LY379268 (0.1 microM, 1 microM and 10 microM) and mGluR5 positive allosteric modulator CDPPB (1 microM and 10 microM) both attenuated potassium-evoked dopamine release, underscoring their role in modulating dopamine neurotransmission in the nucleus accumbens.	Potassium	180-189	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	31-37
29524437-5	2018	We showed that the orthosteric mGluR2 agonist LY379268 (0.1 microM, 1 microM and 10 microM) and mGluR5 positive allosteric modulator CDPPB (1 microM and 10 microM) both attenuated potassium-evoked dopamine release, underscoring their role in modulating dopamine neurotransmission in the nucleus accumbens.	Potassium	180-189	glutamate receptor, ionotropic, kainate 1	Mus musculus	96-102
29741884-4	2018	A formally zerovalent cobalt complex has different structures depending on whether potassium binds; potassium binding gives transfer of two electrons into the eta2-diazoalkane, but the removal of the potassium with crown ether leads to a form with only one electron transferred into an eta1-diazoalkane.	Potassium	83-92	DNA polymerase iota	Homo sapiens	159-163
29741884-4	2018	A formally zerovalent cobalt complex has different structures depending on whether potassium binds; potassium binding gives transfer of two electrons into the eta2-diazoalkane, but the removal of the potassium with crown ether leads to a form with only one electron transferred into an eta1-diazoalkane.	Potassium	83-92	secreted phosphoprotein 1	Homo sapiens	286-290
29741884-4	2018	A formally zerovalent cobalt complex has different structures depending on whether potassium binds; potassium binding gives transfer of two electrons into the eta2-diazoalkane, but the removal of the potassium with crown ether leads to a form with only one electron transferred into an eta1-diazoalkane.	Potassium	100-109	DNA polymerase iota	Homo sapiens	159-163
29741884-4	2018	A formally zerovalent cobalt complex has different structures depending on whether potassium binds; potassium binding gives transfer of two electrons into the eta2-diazoalkane, but the removal of the potassium with crown ether leads to a form with only one electron transferred into an eta1-diazoalkane.	Potassium	100-109	DNA polymerase iota	Homo sapiens	159-163
28791698-5	2018	Correspondingly, the OCT1-deficient individuals had a 1.5-fold stronger increase in heart rate (P = 0.002), a 3.4-fold greater increase in blood glucose (P = 3.0 x 10-5 ), and significantly lower serum potassium levels.	Potassium	202-211	solute carrier family 22 member 1	Homo sapiens	21-25
29134558-9	2018	In this case, DAPA treatment could potentially increase the requirement for mineralocorticoid replacement, directly suggesting that the SGLT2 inhibition-induced natriuretic effect is accompanied by compensatory activation of the RAAS axis, which is essential to keep the serum potassium level within the normal range.	Potassium	277-286	solute carrier family 5 member 2	Homo sapiens	136-141
29806042-2	2018	Even newly released anti-arrhythmic drugs, like ivabradine with HCN channel as a primary target, block the hERG potassium current in overlapping concentration interval.	Potassium	112-121	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	64-67
29806042-2	2018	Even newly released anti-arrhythmic drugs, like ivabradine with HCN channel as a primary target, block the hERG potassium current in overlapping concentration interval.	Potassium	112-121	ETS transcription factor ERG	Homo sapiens	107-111
29648633-3	2018	In the current study we determined the role of urotensin-II in the regulation of transient outward A-type potassium currents (IA) and neuronal excitability in trigeminal ganglion (TG) neurons.	Potassium	106-115	urotensin 2	Homo sapiens	47-59
29602832-4	2018	Drosophila WNK activity in tubules also increased or decreased when bath potassium concentration decreased or increased, respectively.	Potassium	73-82	Wnk kinase	Drosophila melanogaster	11-14
29700922-0	2018	The responses of the inflammatory marker, pentraxin 3, to dietary sodium and potassium interventions.	Potassium	77-86	pentraxin 3	Homo sapiens	42-53
29700922-8	2018	Potassium supplementation inhibited salt-induced increase in pentraxin-3 (0.56 +- 0.21 ng/mL vs 0.68 +- 0.26 ng/mL, P = .015).	Potassium	0-9	pentraxin 3	Homo sapiens	61-72
29700922-10	2018	We found a positive correlation between the ln-transformed concentrations of pentraxin-3 and 24-hour urinary sodium during low and high Na+ periods (r = .269, P = .012) and a negative relationship with 24 hours urinary potassium excretion during high-salt and high-salt plus potassium periods (r = -.246, P = .02).	Potassium	219-228	pentraxin 3	Homo sapiens	77-88
29700922-10	2018	We found a positive correlation between the ln-transformed concentrations of pentraxin-3 and 24-hour urinary sodium during low and high Na+ periods (r = .269, P = .012) and a negative relationship with 24 hours urinary potassium excretion during high-salt and high-salt plus potassium periods (r = -.246, P = .02).	Potassium	275-284	pentraxin 3	Homo sapiens	77-88
29700922-13	2018	Dietary salt and potassium interventions significantly altered circulating pentraxin-3.	Potassium	17-26	pentraxin 3	Homo sapiens	75-86
29699633-8	2018	In addition, PT-miR-17-92-/- mice showed higher levels of serum potassium and phosphonium after the IRI operation.	Potassium	64-73	Mir17 host gene (non-protein coding)	Mus musculus	16-25
29671960-0	2018	Renal potassium handling in carriers of the Gly40Ser mutation of the glucagon receptor suggests a role for glucagon in potassium homeostasis.	Potassium	6-15	glucagon receptor	Homo sapiens	69-86
29668703-5	2018	Here, we demonstrate a novel vasodilatory action of +-PZQ in mesenteric vessels that are precontracted by high potassium-evoked depolarization, an effect previously reported to be associated with agonists of the transient receptor potential melastatin 8 channel (TRPM8).	Potassium	111-120	transient receptor potential cation channel subfamily M member 8	Homo sapiens	212-261
29668703-5	2018	Here, we demonstrate a novel vasodilatory action of +-PZQ in mesenteric vessels that are precontracted by high potassium-evoked depolarization, an effect previously reported to be associated with agonists of the transient receptor potential melastatin 8 channel (TRPM8).	Potassium	111-120	transient receptor potential cation channel subfamily M member 8	Homo sapiens	263-268
29483285-12	2018	We show that the KV8.2 subunit interacts with different Kv2 channels in rods and cones, giving rise to potassium currents with distinct functional properties.	Potassium	103-112	potassium voltage-gated channel modifier subfamily V member 2	Homo sapiens	17-22
29310825-0	2018	Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel.	Potassium	0-9	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	103-109
29310825-1	2018	Kir4.1 in the distal convoluted tubule plays a key role in sensing plasma potassium and in modulating the thiazide-sensitive sodium-chloride cotransporter (NCC).	Potassium	74-83	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	0-6
29310825-3	2018	High potassium intake inhibited the basolateral 40 pS potassium channel (a Kir4.1/5.1 heterotetramer) in the distal convoluted tubule, decreased basolateral potassium conductance, and depolarized the distal convoluted tubule membrane in Kcnj10flox/flox mice, herein referred to as control mice.	Potassium	5-14	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	75-81
29310825-3	2018	High potassium intake inhibited the basolateral 40 pS potassium channel (a Kir4.1/5.1 heterotetramer) in the distal convoluted tubule, decreased basolateral potassium conductance, and depolarized the distal convoluted tubule membrane in Kcnj10flox/flox mice, herein referred to as control mice.	Potassium	5-14	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	237-243
29310825-3	2018	High potassium intake inhibited the basolateral 40 pS potassium channel (a Kir4.1/5.1 heterotetramer) in the distal convoluted tubule, decreased basolateral potassium conductance, and depolarized the distal convoluted tubule membrane in Kcnj10flox/flox mice, herein referred to as control mice.	Potassium	54-63	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	75-81
29310825-4	2018	In contrast, low potassium intake activated Kir4.1, increased potassium currents, and hyperpolarized the distal convoluted tubule membrane.	Potassium	17-26	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	44-50
29310825-5	2018	These effects of dietary potassium intake on the basolateral potassium conductance and membrane potential in the distal convoluted tubule were completely absent in inducible kidney-specific Kir4.1 knockout mice.	Potassium	25-34	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	190-196
29310825-9	2018	Finally, hypokalemia and metabolic alkalosis in kidney-specific Kir4.1 knockout mice were exacerbated by potassium restriction and only partially corrected by a high-potassium diet.	Potassium	105-114	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	64-70
29310825-9	2018	Finally, hypokalemia and metabolic alkalosis in kidney-specific Kir4.1 knockout mice were exacerbated by potassium restriction and only partially corrected by a high-potassium diet.	Potassium	166-175	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	64-70
29310825-10	2018	Thus, Kir4.1 plays an essential role in mediating the effect of dietary potassium intake on NCC activity and potassium homeostasis.	Potassium	72-81	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	6-12
29310825-10	2018	Thus, Kir4.1 plays an essential role in mediating the effect of dietary potassium intake on NCC activity and potassium homeostasis.	Potassium	109-118	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	6-12
28623618-6	2018	The hyperpolarizing effect of ET-1 appears to be orchestrated via modulation of membrane conductances, namely voltage-gated sodium current (I Na) and outward transient potassium current (I KT).	Potassium	168-177	endothelin 1	Rattus norvegicus	30-34
28623618-8	2018	Additionally, ET-1 (100 nM) significantly potentiated the transient component (I KT) of the potassium currents.	Potassium	92-101	endothelin 1	Rattus norvegicus	14-18
29712960-1	2018	We aim to evaluate the association of systolic and diastolic blood pressure (SBP and DBP) with estimated urinary sodium (Na) and potassium(K) excretions, and their gram-to-gram Na/K ratio across various salt-diet regions during 2005-2009 in China.	Potassium	129-138	D-box binding PAR bZIP transcription factor	Homo sapiens	85-88
29367066-6	2018	The magnitude of brush layer lower critical solution temperature reduction was found to follow the order F- &gt; CH3CO2- &gt; Cl- &gt; NO3- ~ Br- &gt; I- &gt; SCN- for the potassium series and Na+ &gt; K+ &gt; Cs+ &gt; Li+ ~ NH4+ for the chloride salts.	Potassium	172-181	NBL1, DAN family BMP antagonist	Homo sapiens	135-138
29681847-9	2018	Reduced nAChR-mediated anti-inflammation due to the loss of nicotinic innervation might lead to the transformation of glial cells and release of inflammatory mediators, lowering the buffering of extracellular potassium and glutamate metabolism.	Potassium	209-218	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	8-13
29432900-0	2018	Thermodynamic analysis of Kex2 activity: The acylation and deacylation steps are potassium- and substrate-dependent.	Potassium	81-90	kexin KEX2	Saccharomyces cerevisiae S288C	26-30
29432900-3	2018	Potassium bound Kex2 with KD=20.3mM.	Potassium	0-9	kexin KEX2	Saccharomyces cerevisiae S288C	16-20
29460236-2	2018	XEN-D0103 is a nanomolar ion channel blocker that selectively inhibits potassium ion flux through the Kv1.5 ion channel.	Potassium	71-80	potassium voltage-gated channel subfamily A member 5	Homo sapiens	102-107
29671960-0	2018	Renal potassium handling in carriers of the Gly40Ser mutation of the glucagon receptor suggests a role for glucagon in potassium homeostasis.	Potassium	119-128	glucagon receptor	Homo sapiens	69-86
29671960-2	2018	Insulin is known to favor potassium entry into cells.	Potassium	26-35	insulin	Homo sapiens	0-7
29590095-6	2018	Our model validates previous experimental observations that both Kir4.1 channels and gap junctions play important roles in regulating the concentration of extracellular potassium.	Potassium	169-178	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	65-71
29566502-1	2018	We analyze the entropic effects of inner pore geometry changes of Kv 1.2 channel during membrane depolarization and their implications for the rate of transmembrane transport of potassium ions.	Potassium	178-187	potassium voltage-gated channel subfamily A member 2	Homo sapiens	66-72
29305421-2	2018	The fast component of the delayed rectifier potassium currents responsible for repolarization of the cardiac action potential, Ikr, is encoded by the human ether-a-go-go related gene (hERG) channel.	Potassium	44-53	ETS transcription factor ERG	Homo sapiens	184-188
29311259-2	2018	ROMK, also known as Kir1.1 (KCNJ1), is the major route for potassium secretion into the pro-urine and plays an indispensable role in regulating serum potassium and urinary concentrations.	Potassium	59-68	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-4
29540778-4	2018	Here we demonstrated that Kir6.1-containing ATP-sensitive potassium (Kir6.1/K-ATP) channel switched microglia from the detrimental M1 phenotype toward the beneficial M2 phenotype.	Potassium	58-67	potassium inwardly-rectifying channel, subfamily J, member 8	Mus musculus	26-32
29540778-4	2018	Here we demonstrated that Kir6.1-containing ATP-sensitive potassium (Kir6.1/K-ATP) channel switched microglia from the detrimental M1 phenotype toward the beneficial M2 phenotype.	Potassium	58-67	potassium inwardly-rectifying channel, subfamily J, member 8	Mus musculus	69-75
29446937-4	2018	Decreasing potassium concentration leads to a contraction of the RhO6 octahedral layers, which may be attributed to a higher covalency of Rh-O bonds.	Potassium	11-20	Rho family GTPase 1	Homo sapiens	65-69
29311259-2	2018	ROMK, also known as Kir1.1 (KCNJ1), is the major route for potassium secretion into the pro-urine and plays an indispensable role in regulating serum potassium and urinary concentrations.	Potassium	150-159	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-4
29311259-5	2018	However, sufficient ROMK levels on the plasma membrane rescued growth on low-potassium medium of yeast cells lacking endogenous potassium channels.	Potassium	77-86	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	20-24
29311259-7	2018	Therefore, we used a synthetic genetic array to identify non-essential genes that reduce the plasma membrane pool of ROMK in potassium-sensitive yeast cells.	Potassium	125-134	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	117-121
29274961-0	2018	Technical note: Development and validation of a new method for the quantification of soluble and micellar calcium, magnesium, and potassium in milk.	Potassium	130-139	Weaning weight-maternal milk	Bos taurus	143-147
29464197-9	2018	Astrocytes from Mecp2-deficient mice express significantly less Kir4.1 mRNA and protein, which translates into a &gt;50% deficiency in Ba2+-sensitive Kir4.1-mediated currents, and impaired extracellular potassium dynamics.	Potassium	203-212	methyl CpG binding protein 2	Mus musculus	16-21
29146137-6	2018	RESULTS: Phosphorus, potassium, and sodium additives were present on the ingredient list in 37%, 9%, and 72% of MPF, respectively.	Potassium	21-30	mesothelin	Homo sapiens	112-115
29146137-9	2018	CONCLUSIONS: The use of additives in packaged MPF products as indicated by the ingredient list can significantly contribute to the dietary phosphorus and potassium loads in patients with CKD.	Potassium	154-163	mesothelin	Homo sapiens	46-49
29129401-7	2018	Mice lacking both claudin-10 and -16 in the thick ascending limb recruited downstream compensatory mechanisms and showed hypertrophic distal convoluted tubules with changes in gene expression and phosphorylation of ion transporters in this segment, presumably triggered by the mild decrease in serum potassium.	Potassium	300-309	claudin 10	Mus musculus	18-36
28915228-5	2018	Of the total 766 patients, those with rare variants in exon 13 of either SCNN1B or SCNN1G had a significantly earlier onset of hypertension (24.7 +- 7.5 vs. 29.0 +- 7.7 years, P = 0.015) and lower serum potassium (3.57 +- 0.59 vs. 3.96 +- 0.41 mmol/l, P = 0.007) than those without rare variants.	Potassium	203-212	sodium channel epithelial 1 subunit beta	Homo sapiens	73-79
28915228-5	2018	Of the total 766 patients, those with rare variants in exon 13 of either SCNN1B or SCNN1G had a significantly earlier onset of hypertension (24.7 +- 7.5 vs. 29.0 +- 7.7 years, P = 0.015) and lower serum potassium (3.57 +- 0.59 vs. 3.96 +- 0.41 mmol/l, P = 0.007) than those without rare variants.	Potassium	203-212	sodium channel epithelial 1 subunit gamma	Homo sapiens	83-89
29483649-5	2018	Enzymatic analysis has confirmed that efficient GTP hydrolysis by MFN1 requires potassium.	Potassium	80-89	mitofusin 1	Homo sapiens	66-70
29294000-8	2018	Electrophysiological examinations in transfected HEK293 cells showed that both the L319R and N255K mutants resulted in reduced potassium currents and respective altered gating properties, with a dominant negative effect on the Kv1.1 wild-type channel.	Potassium	127-136	potassium voltage-gated channel subfamily A member 1	Homo sapiens	227-232
29474462-2	2018	Retinal Muller cells maintain water homeostasis and potassium concentration via inwardly rectifying Kir4.1 channels.	Potassium	52-61	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	100-106
29459730-1	2018	NaK and other non-selective channels are able to conduct both sodium (Na+) and potassium (K+) with equally high efficiency.	Potassium	79-88	TANK binding kinase 1	Homo sapiens	0-3
29031006-6	2018	Glucagon-like peptide-1 (GLP-1) has been reported to increase glomerular filtration rate (GFR), renal blood flow, and the fractional excretion both of sodium and potassium, with renal GLP-1 receptors present in afferent arteriolar vascular smooth muscle cells, glomerular endothelial cells and macrophages, juxtaglomerular cells, and the proximal tubule, perhaps mediating the greater natriuresis seen after oral than intravenous sodium.	Potassium	162-171	glucagon	Homo sapiens	0-23
29237822-0	2018	Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.	Potassium	0-9	WNK lysine deficient protein kinase 1	Mus musculus	65-69
29237822-7	2018	The formation of WNK bodies requires an evolutionarily conserved cysteine-rich hydrophobic motif harbored within a unique N-terminal exon of KS-WNK1.	Potassium	141-143	WNK lysine deficient protein kinase 1	Mus musculus	144-148
29237822-8	2018	We propose that WNK bodies are not pathological aggregates, but rather are KS-WNK1-dependent microdomains of the DCT cytosol that modulate WNK signaling during physiological shifts in potassium balance.	Potassium	75-77	WNK lysine deficient protein kinase 1	Mus musculus	78-82
29237822-8	2018	We propose that WNK bodies are not pathological aggregates, but rather are KS-WNK1-dependent microdomains of the DCT cytosol that modulate WNK signaling during physiological shifts in potassium balance.	Potassium	184-193	WNK lysine deficient protein kinase 1	Mus musculus	78-82
28374925-7	2018	The clinical profile associated with inactivating HNRNPK mutations supports the idea that the associated disorder should be considered as a distinct nosologic entity clinically related to KS, and that the condition should be considered in differential diagnosis with KS, in particular in subjects exhibiting brain malformation (nodular heterotopia), craniosynostosis, and polydactyly.	Potassium	188-190	heterogeneous nuclear ribonucleoprotein K	Homo sapiens	50-56
28374925-7	2018	The clinical profile associated with inactivating HNRNPK mutations supports the idea that the associated disorder should be considered as a distinct nosologic entity clinically related to KS, and that the condition should be considered in differential diagnosis with KS, in particular in subjects exhibiting brain malformation (nodular heterotopia), craniosynostosis, and polydactyly.	Potassium	267-269	heterogeneous nuclear ribonucleoprotein K	Homo sapiens	50-56
29031006-6	2018	Glucagon-like peptide-1 (GLP-1) has been reported to increase glomerular filtration rate (GFR), renal blood flow, and the fractional excretion both of sodium and potassium, with renal GLP-1 receptors present in afferent arteriolar vascular smooth muscle cells, glomerular endothelial cells and macrophages, juxtaglomerular cells, and the proximal tubule, perhaps mediating the greater natriuresis seen after oral than intravenous sodium.	Potassium	162-171	glucagon	Homo sapiens	25-30
29326302-9	2018	Thus, our study provides in vivo evidence that, in response to a low-potassium diet, ClC-K and barttin play important roles in the activation of the WNK4-SPAK-NCC cascade and blood pressure regulation.	Potassium	69-78	barttin CLCNK type accessory beta subunit	Mus musculus	95-102
29384476-6	2018	Interestingly, fatigue in P2ry1 mutants was more greatly exacerbated by exposure to high potassium than in control mice.	Potassium	89-98	purinergic receptor P2Y, G-protein coupled 1	Mus musculus	26-31
28892166-10	2018	The Ka/Ks ratio (&gt;1) in the SHB region indicates that anti-HBs might have exerted selection pressure on the HBsAg.	Potassium	7-9	SH2 domain containing adaptor protein B	Homo sapiens	31-34
29245016-12	2018	Finally, electrophysiological studies showed that the inwardly rectifying potassium current (IK1) was evenly present in AF- and Ctr-CMPC in basal conditions and similarly disappeared after TGF-beta1 exposure.	Potassium	74-83	IKAROS family zinc finger 1	Homo sapiens	93-96
29245016-12	2018	Finally, electrophysiological studies showed that the inwardly rectifying potassium current (IK1) was evenly present in AF- and Ctr-CMPC in basal conditions and similarly disappeared after TGF-beta1 exposure.	Potassium	74-83	transforming growth factor beta 1	Homo sapiens	189-198
29384476-7	2018	High potassium itself increased cytosolic levels of calcium in TPSCs, a response which was also reduced P2ry1 mutants.	Potassium	5-14	purinergic receptor P2Y, G-protein coupled 1	Mus musculus	104-109
29326302-9	2018	Thus, our study provides in vivo evidence that, in response to a low-potassium diet, ClC-K and barttin play important roles in the activation of the WNK4-SPAK-NCC cascade and blood pressure regulation.	Potassium	69-78	WNK lysine deficient protein kinase 4	Mus musculus	149-153
30408810-10	2018	The serum CT-1 concentrations were positively correlated with the 24-h urinary sodium-to-potassium (Na/K) excretion ratios during both of the LS and HS diet intervention periods in SS subjects (r = 0.621, p < 0.01), but this correlation was not evident in SR subjects (r = 0.208, p = 0.107).	Potassium	89-98	cardiotrophin 1	Homo sapiens	10-14
29374044-0	2018	Inhibitory Effect of Vascular Endothelial Growth Factor on the Slowly Activating Delayed Rectifier Potassium Current in Guinea Pig Ventricular Myocytes.	Potassium	99-108	Vegfa	Cavia porcellus	21-55
29374044-3	2018	In the present study, we investigated the effects of different concentrations of VEGF on delayed rectifier potassium currents (IK) in guinea pig ventricular myocytes and their effects on action potential (AP) parameters.	Potassium	107-116	Vegfa	Cavia porcellus	81-85
29374044-7	2018	We found that VEGF inhibited the slowly activating delayed rectifier potassium current (IKs) in a concentration-dependent manner (18.13+-1.04 versus 12.73+-0.34, n=5, P=0.001; 12.73+-0.34 versus 9.05+-1.20, n=5, P=0.036) and prolonged AP duration (894.5+-36.92 versus 746.3+-33.71, n=5, P=0.021).	Potassium	69-78	Vegfa	Cavia porcellus	14-18
29203171-3	2018	This functionality allows the classical NLRP3 pathway to serve as a highly sensitive, but non-specific surveillance mechanism responding to any type of perturbation that breaches plasma membrane integrity and the associated potassium gradient across the membrane.	Potassium	224-233	NLR family pyrin domain containing 3	Homo sapiens	40-45
29203171-4	2018	Here, we review our current knowledge on potassium efflux-dependent NLRP3 activation, with a special focus on how major cell death programs are rendered pro-inflammatory by secondary NLRP3 activation.	Potassium	41-50	NLR family pyrin domain containing 3	Homo sapiens	68-73
29203171-4	2018	Here, we review our current knowledge on potassium efflux-dependent NLRP3 activation, with a special focus on how major cell death programs are rendered pro-inflammatory by secondary NLRP3 activation.	Potassium	41-50	NLR family pyrin domain containing 3	Homo sapiens	183-188
29338715-12	2018	ND4 Ka/Ks ratios were highly correlated with SST (Mantel, p-value: 0.0001; GLM, p-value: 0.00001) and thus may be related to climate adaptation throughout penguin speciation.	Potassium	7-9	ND4	Pygoscelis adeliae	0-3
29326302-6	2018	In Bsndneo/neo mice, SPAK and NCC activation after consuming a low-potassium diet was clearly impaired compared with that in wild-type (WT) mice.	Potassium	67-76	serine/threonine kinase 39	Mus musculus	21-25
29326302-7	2018	In ex vivo kidney slice experiment, the increase in pNCC and SPAK in low-potassium medium was also impaired in Bsndneo/neo mice.	Potassium	73-82	serine/threonine kinase 39	Mus musculus	61-65
29317612-3	2018	We discovered the development of this activity in the CA1 region of horizontal slices after prolonged interictal-like epileptiform activity in the CA3 region that was provoked by incubation in high potassium artificial cerebrospinal fluid.	Potassium	198-207	carbonic anhydrase 1	Rattus norvegicus	54-57
28987626-0	2018	NO involvement in the inhibition of ghrelin on voltage-dependent potassium currents in rat hippocampal cells.	Potassium	65-74	ghrelin and obestatin prepropeptide	Rattus norvegicus	36-43
29359681-0	2018	Involvement of NLRP3 inflammasome in the impacts of sodium and potassium on insulin resistance in normotensive Asians.	Potassium	63-72	NLR family pyrin domain containing 3	Homo sapiens	15-20
29359681-0	2018	Involvement of NLRP3 inflammasome in the impacts of sodium and potassium on insulin resistance in normotensive Asians.	Potassium	63-72	insulin	Homo sapiens	76-83
28987626-2	2018	In this study, we examined the effect of ghrelin on voltage-dependent potassium (K+) currents in hippocampal cells of 1-3 days SD rats by whole-cell patch-clamp technique, and discussed whether NO was involved in this process.	Potassium	70-79	ghrelin and obestatin prepropeptide	Rattus norvegicus	41-48
30854950-6	2018	RESULTS: Mineralocorticoid receptor antagonists result in significant improvement in blood pressure and serum potassium level among patients with primary aldosteronism.	Potassium	110-119	nuclear receptor subfamily 3 group C member 2	Homo sapiens	9-35
30070159-2	2018	KChIPs constitute a group of specific auxiliary beta-subunits for Kv4 channels, the molecular substrate of transient potassium currents in both neuronal and non-neuronal tissues.	Potassium	117-126	potassium voltage-gated channel subfamily C member 1	Homo sapiens	66-69
30138927-10	2018	RESULTS: Elevated extracellular potassium prevented the priming factor IL-1alpha from inducing the production of reactive oxygen species (ROS).	Potassium	32-41	interleukin 1 alpha	Homo sapiens	71-80
29669325-1	2018	BACKGROUND/AIMS: The replacement of the amino acid valine at position 388 (Shaker position 438) in hKv1.3 channels or at the homologue position 370 in hKv1.2 channels resulted in a channel with two different ion conducting pathways: One pathway was the central, potassium-selective alpha-pore, that was sensitive to block by peptide toxins (CTX or KTX in the hKv1.3_V388C channel and CTX or MTX in the hKv1.2_V370C channel).	Potassium	262-271	potassium voltage-gated channel subfamily A member 2	Homo sapiens	151-157
28677029-6	2018	The alteration of KCC2 expression affects GABAergic and glycinergic neurotransmissions, because KCC2 is a potassium-chloride exporter and serves to maintain intracellular chloride concentration.	Potassium	106-115	solute carrier family 12 member 5	Homo sapiens	18-22
28826578-4	2018	RESULTS: SGLT2 inhibitors induce small increases in serum concentrations of magnesium, potassium and phosphate.	Potassium	87-96	solute carrier family 5 member 2	Homo sapiens	9-14
30099444-15	2018	CONCLUSION: We found that in patients with CKD, urinary sodium and potassium excretion is closely correlated to renal handling of uric acid, which was pronounced in hypertensive patients with low eGFR.	Potassium	67-76	epidermal growth factor receptor	Homo sapiens	196-200
28677029-6	2018	The alteration of KCC2 expression affects GABAergic and glycinergic neurotransmissions, because KCC2 is a potassium-chloride exporter and serves to maintain intracellular chloride concentration.	Potassium	106-115	solute carrier family 12 member 5	Homo sapiens	96-100
29448255-0	2018	Intrathecal Administration of CXCL1 Enhances Potassium Currents in Microglial Cells.	Potassium	45-54	chemokine (C-X-C motif) ligand 1	Mus musculus	30-35
29045814-0	2018	Role of KCC2-dependent potassium efflux in 4-Aminopyridine-induced Epileptiform synchronization.	Potassium	23-32	solute carrier family 12, member 5	Mus musculus	8-12
29045814-9	2018	Our model predicts that interneuron stimulation triggered an increase of interneuron firing, which was accompanied by an increase in the intracellular chloride concentration and a subsequent KCC2-dependent gradual accumulation of the extracellular potassium promoting epileptiform ictal activity.	Potassium	248-257	solute carrier family 12, member 5	Mus musculus	191-195
29448255-3	2018	In this study, we explore the effect of intrathecal injection of CXCL1 on potassium currents, expressed in CX3CR1-Green Fluorescent Protein labeled microglia in transgenic mice.	Potassium	74-83	chemokine (C-X-C motif) ligand 1	Mus musculus	65-70
29448255-3	2018	In this study, we explore the effect of intrathecal injection of CXCL1 on potassium currents, expressed in CX3CR1-Green Fluorescent Protein labeled microglia in transgenic mice.	Potassium	74-83	chemokine (C-X3-C motif) receptor 1	Mus musculus	107-113
29448255-4	2018	The results showed that CXCL1 hyperpolarized the cells by enhancing inward rectifying potassium currents and increasing the membrane area, suggesting an activating effect on microglia.	Potassium	86-95	chemokine (C-X-C motif) ligand 1	Mus musculus	24-29
29273710-7	2017	On in-vitro analysis, potassium under Th17 polarizing conditions significantly inhibited IL-17 and interferon-[Formula: see text] expression while favoring the induction of FoxP3+ T cells.	Potassium	22-31	interleukin 17A	Homo sapiens	89-94
29273710-7	2017	On in-vitro analysis, potassium under Th17 polarizing conditions significantly inhibited IL-17 and interferon-[Formula: see text] expression while favoring the induction of FoxP3+ T cells.	Potassium	22-31	forkhead box P3	Homo sapiens	173-178
29383177-4	2017	The wild-type (WT) or mutant T361S of Kv4.3 protein (encoded by KCND3) were co-expressed with the auxiliary subunit K+ channel-Interacting Protein (KChIP2) in HEK293 cells, and transient outward potassium current (Ito) were recorded using patch-clamp methods, and the surface or total protein levels of Kv4.3 were analyzed by western blot.	Potassium	195-204	potassium voltage-gated channel subfamily D member 3	Homo sapiens	38-43
29234037-3	2017	We have previously demonstrated that during pathological conditions such as polycystic kidney disease, polycystin 2 (TRPP2) inhibits the activity of potassium-selective MSCs through a filamin A-mediated cytoskeletal effect, and renders tubular epithelial cells susceptible to apoptosis.	Potassium	149-158	polycystin 2, transient receptor potential cation channel	Homo sapiens	103-115
29234037-3	2017	We have previously demonstrated that during pathological conditions such as polycystic kidney disease, polycystin 2 (TRPP2) inhibits the activity of potassium-selective MSCs through a filamin A-mediated cytoskeletal effect, and renders tubular epithelial cells susceptible to apoptosis.	Potassium	149-158	polycystin 2, transient receptor potential cation channel	Homo sapiens	117-122
29234037-3	2017	We have previously demonstrated that during pathological conditions such as polycystic kidney disease, polycystin 2 (TRPP2) inhibits the activity of potassium-selective MSCs through a filamin A-mediated cytoskeletal effect, and renders tubular epithelial cells susceptible to apoptosis.	Potassium	149-158	filamin A	Homo sapiens	184-193
29234037-5	2017	In this study we use a combination of electrophysiology, structured illumination microscopy, and fluorescence recovery after photobleaching (FRAP) to examine the dynamic nature of the TRPP2-mediated cytoskeletal inhibition of the potassium-selective MSC TREK1.	Potassium	230-239	polycystin 2, transient receptor potential cation channel	Homo sapiens	184-189
29358904-1	2017	Inwardly rectifying potassium (Kir) 4.1 channels in astrocytes regulate neuronal excitability by mediating spatial potassium buffering.	Potassium	20-29	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	31-39
29212953-3	2017	Here, we report an unexpected role for the ubiquitin ligase Siah1 in adrenal gland development and PA. Siah1a-/- mice exhibit altered adrenal gland morphology, as reflected by a diminished X-zone, enlarged medulla, and dysregulated zonation of the glomerulosa as well as increased aldosterone levels and aldosterone target gene expression and reduced plasma potassium levels.	Potassium	358-367	siah E3 ubiquitin protein ligase 1	Homo sapiens	60-65
29126768-4	2017	To elucidate the mechanisms underlying 5-HT1AAR supersensitivity in Tph2-/- mice, we characterized the activation of G protein-coupled inwardly-rectifying potassium (GIRK) conductance by the 5-HT1A receptor agonist 5-carboxamidotryptamine using whole-cell recordings from serotonergic neurons in dorsal raphe nucleus.	Potassium	155-164	tryptophan hydroxylase 2	Mus musculus	68-72
29212953-3	2017	Here, we report an unexpected role for the ubiquitin ligase Siah1 in adrenal gland development and PA. Siah1a-/- mice exhibit altered adrenal gland morphology, as reflected by a diminished X-zone, enlarged medulla, and dysregulated zonation of the glomerulosa as well as increased aldosterone levels and aldosterone target gene expression and reduced plasma potassium levels.	Potassium	358-367	siah E3 ubiquitin protein ligase 1A	Mus musculus	103-109
29206101-5	2017	Here, we show that serotonin (5HT), which is known to regulate gamma power, acts via 5HT2A receptors to suppress an inward-rectifying potassium conductance in FSIs.	Potassium	134-143	5-hydroxytryptamine (serotonin) receptor 2A	Mus musculus	85-90
29126483-6	2017	The analytical features provided by the microsystem after the optimization process were a linear range from 6.3 to 630 mg L-1 and a detection limit of 0.51 mg L-1 for the potassium electrode, a linear range from 10 to 1000 mg L-1 and a detection limit of 1.58 mg L-1 for the chloride electrode and a linear range from 10 to 1000 mg L-1 and a detection limit of 3.37 mg L-1 for the nitrate electrode with a reproducibility (RSD) of 4%, 2% and 3% respectively.	Potassium	171-180	immunoglobulin kappa variable 1-16	Homo sapiens	159-162
29126483-6	2017	The analytical features provided by the microsystem after the optimization process were a linear range from 6.3 to 630 mg L-1 and a detection limit of 0.51 mg L-1 for the potassium electrode, a linear range from 10 to 1000 mg L-1 and a detection limit of 1.58 mg L-1 for the chloride electrode and a linear range from 10 to 1000 mg L-1 and a detection limit of 3.37 mg L-1 for the nitrate electrode with a reproducibility (RSD) of 4%, 2% and 3% respectively.	Potassium	171-180	immunoglobulin kappa variable 1-16	Homo sapiens	159-162
29126483-6	2017	The analytical features provided by the microsystem after the optimization process were a linear range from 6.3 to 630 mg L-1 and a detection limit of 0.51 mg L-1 for the potassium electrode, a linear range from 10 to 1000 mg L-1 and a detection limit of 1.58 mg L-1 for the chloride electrode and a linear range from 10 to 1000 mg L-1 and a detection limit of 3.37 mg L-1 for the nitrate electrode with a reproducibility (RSD) of 4%, 2% and 3% respectively.	Potassium	171-180	immunoglobulin kappa variable 1-16	Homo sapiens	159-162
29126483-6	2017	The analytical features provided by the microsystem after the optimization process were a linear range from 6.3 to 630 mg L-1 and a detection limit of 0.51 mg L-1 for the potassium electrode, a linear range from 10 to 1000 mg L-1 and a detection limit of 1.58 mg L-1 for the chloride electrode and a linear range from 10 to 1000 mg L-1 and a detection limit of 3.37 mg L-1 for the nitrate electrode with a reproducibility (RSD) of 4%, 2% and 3% respectively.	Potassium	171-180	immunoglobulin kappa variable 1-16	Homo sapiens	159-162
29126483-6	2017	The analytical features provided by the microsystem after the optimization process were a linear range from 6.3 to 630 mg L-1 and a detection limit of 0.51 mg L-1 for the potassium electrode, a linear range from 10 to 1000 mg L-1 and a detection limit of 1.58 mg L-1 for the chloride electrode and a linear range from 10 to 1000 mg L-1 and a detection limit of 3.37 mg L-1 for the nitrate electrode with a reproducibility (RSD) of 4%, 2% and 3% respectively.	Potassium	171-180	immunoglobulin kappa variable 1-16	Homo sapiens	159-162
28961511-7	2017	Kn/Ks values were between 0 and 1, suggesting the purifying selection among BnAP2/ERF TFs.	Potassium	3-5	floral homeotic protein APETALA 2	Brassica napus	76-81
29126768-4	2017	To elucidate the mechanisms underlying 5-HT1AAR supersensitivity in Tph2-/- mice, we characterized the activation of G protein-coupled inwardly-rectifying potassium (GIRK) conductance by the 5-HT1A receptor agonist 5-carboxamidotryptamine using whole-cell recordings from serotonergic neurons in dorsal raphe nucleus.	Potassium	155-164	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	191-206
28934190-0	2017	People with the major alleles of ATP2B1 rs17249754 increases the risk of hypertension in high ratio of sodium and potassium, and low calcium intakes.	Potassium	114-123	ATPase plasma membrane Ca2+ transporting 1	Homo sapiens	33-39
29111379-2	2017	Another disease also caused by mutations in the gene SCN4A is called myotonia aggravated by potassium (OMIM 170500, 613345).	Potassium	92-101	sodium voltage-gated channel alpha subunit 4	Homo sapiens	53-58
29087023-3	2017	Rank correlation analysis revealed that interleukin 6 expression exhibited significant positive correlations with urinary sodium (R = .13) and sodium to potassium ratio (R = .13).	Potassium	153-162	interleukin 6	Homo sapiens	40-53
28643868-11	2017	This potassium battery can be tapped by opening AKT2-like potassium channels and then enables the ATP-independent energization of other transport processes, such as the reloading of sucrose.	Potassium	5-14	AKT serine/threonine kinase 2	Homo sapiens	48-52
29114015-7	2017	By contrast, high HKT1 expression in the root repressed lateral root development, which could be partially rescued by addition of potassium.	Potassium	130-139	high-affinity K+ transporter 1	Arabidopsis thaliana	18-22
28976587-11	2017	CONCLUSION: In patients with renal insufficiency and hyperkalemia, 5 units of insulin reduced serum potassium to the same extent as 10 units of insulin but with a lower rate of hypoglycemia.	Potassium	100-109	insulin	Homo sapiens	78-85
28992755-10	2017	Drug-induced enhancement of an alternative potassium current, IKATP, also reduced APD by up to 21%.	Potassium	43-52	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	62-67
29208215-2	2017	The present study assessed the association of plasma potassium (cK) with serum aldosterone and insulin concentrations, since these hormones are involved in the regulation of potassium homeostasis.	Potassium	53-62	insulin	Bos taurus	95-102
29033128-4	2017	Instead, detection of cytosolic DNA by the cGAS-STING axis induces a cell death program initiating potassium efflux upstream of NLRP3.	Potassium	99-108	NLR family pyrin domain containing 3	Homo sapiens	128-133
28729291-2	2017	Here, we show that the NLRP3-activating agonists, ATP and nigericin, prevent STING pathway activation in association with mitochondrial fragmentation; however, the suppression of the STING pathway and mitochondria fission were not dependent on NLRP3 or potassium efflux.	Potassium	253-262	NLR family pyrin domain containing 3	Homo sapiens	23-28
29170665-9	2017	This IL-1beta secretion was regulated by the NLRP3 inflammasome and was dependent on potassium efflux and Caspase-1.	Potassium	85-94	interleukin 1 beta	Homo sapiens	5-13
28918394-5	2017	When ApoL1 and lipid were allowed to interact at low pH and were then brought to neutral pH, chloride permeability was suppressed, and potassium permeability was activated.	Potassium	135-144	apolipoprotein L1	Homo sapiens	5-10
28918394-6	2017	Both chloride and potassium permeability linearly correlated with the mass of ApoL1 in the reaction mixture, and both exhibited lipid selectivity, requiring the presence of negatively charged lipids for activity.	Potassium	18-27	apolipoprotein L1	Homo sapiens	78-83
28976808-1	2017	In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow IKS potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias.	Potassium	68-77	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	29-34
28976808-1	2017	In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow IKS potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias.	Potassium	68-77	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	40-45
28976808-1	2017	In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow IKS potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias.	Potassium	68-77	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	157-162
28976808-1	2017	In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow IKS potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias.	Potassium	68-77	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	167-172
28988768-5	2017	KCNK3 antagonizes norepinephrine-induced membrane depolarization by promoting potassium efflux in brown adipocytes.	Potassium	78-87	potassium channel, subfamily K, member 3	Mus musculus	0-5
28833536-6	2017	Both recurrent cases showed complete KS remission after tapering immunosuppression therapy and/or switching a calcineurin inhibitor to a mammalian target of rapamycin inhibitor.	Potassium	37-39	mechanistic target of rapamycin kinase	Homo sapiens	137-166
28888605-2	2017	Acidemia negatively affects the cellular response to insulin and may therefore result in deranged glucose, potassium, and phosphorus homeostasis.	Potassium	107-116	insulin	Bos taurus	53-60
28526352-0	2017	Stretch-activated potassium currents in the heart: Focus on TREK-1 and arrhythmias.	Potassium	18-27	potassium two pore domain channel subfamily K member 2	Homo sapiens	60-66
29110762-6	2017	Recent experimental evidence has shown that aberrant efflux of intracellular potassium is an early event in APOL1-induced death of human embryonic kidney cells.	Potassium	77-86	apolipoprotein L1	Homo sapiens	108-113
29110762-7	2017	Here, we discuss the possibility that abnormal efflux of cellular potassium or other cations may be relevant to the pathogenesis of APOL1 nephropathy.	Potassium	66-75	apolipoprotein L1	Homo sapiens	132-137
28602864-7	2017	Thus, the potassium/sodium/calcium exchanger of NCKX3 KO mice proceeded normally in this study.	Potassium	10-19	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	48-53
29031279-1	2017	We report measurements of rate coefficients at T   600 K for rotationally inelastic collisions of NaK molecules in the 2(A)1Sigma+ electronic state with helium, argon, and potassium atom perturbers.	Potassium	172-181	TANK binding kinase 1	Homo sapiens	98-101
28978809-3	2017	Using the ApoE-deficient mouse model, we demonstrated for the first time to our knowledge that reduced dietary potassium (0.3%) promoted atherosclerotic vascular calcification and increased aortic stiffness, compared with normal (0.7%) potassium-fed mice.	Potassium	111-120	apolipoprotein E	Mus musculus	10-14
28904126-5	2017	Treatment of primary monocytes with the NLRP3 inhibitor MCC950 or with extracellular potassium significantly reduced IL-1beta cleavage and release in response to T. gondii infection, without affecting the release of TNF-alpha, and indicated a role for the inflammasome sensor NLRP3 and for potassium efflux in T. gondii-induced IL-1beta production.	Potassium	85-94	NLR family pyrin domain containing 3	Homo sapiens	276-281
28904126-5	2017	Treatment of primary monocytes with the NLRP3 inhibitor MCC950 or with extracellular potassium significantly reduced IL-1beta cleavage and release in response to T. gondii infection, without affecting the release of TNF-alpha, and indicated a role for the inflammasome sensor NLRP3 and for potassium efflux in T. gondii-induced IL-1beta production.	Potassium	290-299	NLR family pyrin domain containing 3	Homo sapiens	40-45
28904126-8	2017	To our knowledge, these findings are the first to identify NLRP3 as an inflammasome sensor for T. gondii in primary human peripheral blood cells and to define an upstream regulator of its activation through the release of intracellular potassium.	Potassium	236-245	NLR family pyrin domain containing 3	Homo sapiens	59-64
28978809-5	2017	Mechanistically, reduction in the potassium concentration to the lower limit of the physiological range increased intracellular calcium, which activated a cAMP response element-binding protein (CREB) signal that subsequently enhanced autophagy and promoted vascular smooth muscle cell (VSMC) calcification.	Potassium	34-43	cAMP responsive element binding protein 1	Mus musculus	155-192
28978809-5	2017	Mechanistically, reduction in the potassium concentration to the lower limit of the physiological range increased intracellular calcium, which activated a cAMP response element-binding protein (CREB) signal that subsequently enhanced autophagy and promoted vascular smooth muscle cell (VSMC) calcification.	Potassium	34-43	cAMP responsive element binding protein 1	Mus musculus	194-198
28978809-6	2017	Inhibition of calcium signals and knockdown of either CREB or ATG7, an autophagy regulator, attenuated VSMC calcification induced by low potassium.	Potassium	137-146	cAMP responsive element binding protein 1	Mus musculus	54-58
28978809-6	2017	Inhibition of calcium signals and knockdown of either CREB or ATG7, an autophagy regulator, attenuated VSMC calcification induced by low potassium.	Potassium	137-146	autophagy related 7	Mus musculus	62-66
28978809-7	2017	Consistently, elevated autophagy and CREB signaling were demonstrated in the calcified arteries from low potassium diet-fed mice as well as aortic arteries exposed to low potassium ex vivo.	Potassium	105-114	cAMP responsive element binding protein 1	Mus musculus	37-41
28978809-7	2017	Consistently, elevated autophagy and CREB signaling were demonstrated in the calcified arteries from low potassium diet-fed mice as well as aortic arteries exposed to low potassium ex vivo.	Potassium	171-180	cAMP responsive element binding protein 1	Mus musculus	37-41
28701322-8	2017	In whole cell recordings from slices in vitro, AT1AR-GFP neurons exhibited voltage-activated potassium currents, including the transient outward current and the M-type potassium current.	Potassium	93-102	angiotensin II receptor type 1	Homo sapiens	47-52
28877968-6	2017	In a small fraction of cells, there was a component of calcium-dependent potassium current that showed frequency-dependent reduction, but the contribution to overall potassium current reduction was almost always much smaller than that of Kv3-mediated current.	Potassium	73-82	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	238-241
28701322-8	2017	In whole cell recordings from slices in vitro, AT1AR-GFP neurons exhibited voltage-activated potassium currents, including the transient outward current and the M-type potassium current.	Potassium	168-177	angiotensin II receptor type 1	Homo sapiens	47-52
28856417-3	2017	Activity of HBD-1 and Pep-B was determined against actively growing M. tb in vitro, inside monocyte-derived macrophages (MDMs) and dormant bacilli in in vitro potassium deficiency and human peripheral blood mononuclear cell (PBMC) granuloma models using colony-forming unit enumeration.	Potassium	159-168	defensin beta 1	Homo sapiens	12-17
28856417-3	2017	Activity of HBD-1 and Pep-B was determined against actively growing M. tb in vitro, inside monocyte-derived macrophages (MDMs) and dormant bacilli in in vitro potassium deficiency and human peripheral blood mononuclear cell (PBMC) granuloma models using colony-forming unit enumeration.	Potassium	159-168	peptidase B	Homo sapiens	22-27
28639369-8	2017	Furthermore, renal markers (creatinine and NGAL) closely associated with potassium and glucose.	Potassium	73-82	lipocalin 2	Homo sapiens	43-47
28499801-7	2017	Univariate Cox regression identified potassium levels outside the interval of &lt;3.5 to 4.5mmol/L to be a risk factor for both in-hospital and long-term death.	Potassium	37-46	cytochrome c oxidase subunit 8A	Homo sapiens	11-14
28734179-7	2017	The p.Asn439Lys and p.Asp445Asn may interfere in binding interactions of MTHFD1 protein with cesium cation and potassium.	Potassium	111-120	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	Homo sapiens	73-79
27882824-3	2017	A phosphorus level of at least 3 mM and K:P molar ratio over 3 were necessary to form MPP, which showed higher content rate of phosphorus and potassium in precipitate.	Potassium	142-151	M-phase phosphoprotein 6	Homo sapiens	86-89
29955681-10	2017	Consumption of "pasta mixed dishes" was associated with a 5% increase in both potassium and sodium intakes (~150 and 190 mg/d, respectively).	Potassium	78-87	solute carrier family 45 member 1	Homo sapiens	16-21
28748724-4	2017	Areas covered: Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been linked with the scarce, but serious, complication of euglycemic diabetic ketoacidosis, as well as with an increase in serum potassium, magnesium and phosphorus levels.	Potassium	199-208	solute carrier family 5 member 2	Homo sapiens	15-45
28748724-4	2017	Areas covered: Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been linked with the scarce, but serious, complication of euglycemic diabetic ketoacidosis, as well as with an increase in serum potassium, magnesium and phosphorus levels.	Potassium	199-208	solute carrier family 5 member 2	Homo sapiens	47-52
28748724-7	2017	Insulin administration is associated with a reduction in serum potassium, magnesium and phosphorus concentration, along with reduced renal magnesium excretion.	Potassium	63-72	insulin	Homo sapiens	0-7
29076349-2	2017	Potassium efflux through Kir1.1 compliments the role of transporters and sodium channels that are the targets of known diuretics.	Potassium	0-9	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	25-31
27615678-10	2017	The presence of a potassium-binding pocket within the active site of mammalian TyrRS compensates the absence of the second lysine in the KMSKS motif.	Potassium	18-27	tyrosyl-tRNA synthetase 1	Homo sapiens	79-84
29056256-5	2017	Treatment with the potassium ionophore nigericin significantly increased the level of activated caspase-1.	Potassium	19-28	caspase 1	Homo sapiens	96-105
28567665-1	2017	In adulthood, an induced nephron-specific deficiency of alphaENaC (Scnn1a) resulted in pseudohypoaldosteronism type 1 (PHA-1) with sodium loss, hyperkalemia, and metabolic acidosis that is rescued through high-sodium/low-potassium (HNa+/LK+) diet.	Potassium	221-230	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	67-73
28993757-11	2017	Thus, we speculated this insulin-induced sharp drop in serum potassium levels as potentiating the patient"s already existing advanced diabetic neuropathy, thereby leading to muscle cramping.	Potassium	61-70	insulin	Homo sapiens	25-32
28993757-13	2017	This tilted our diagnosis toward the insulin-induced acute drop in serum potassium levels as the most likely etiology underlying the patient"s cramps.	Potassium	73-82	insulin	Homo sapiens	37-44
28849814-5	2017	In this work, we employ microsecond-scale all-atom molecular dynamics simulations to investigate the differences in the structural ensembles in sodium-bound/unbound and potassium-bound/unbound thrombin.	Potassium	169-178	coagulation factor II, thrombin	Homo sapiens	193-201
28849814-10	2017	Our study of thrombin in the presence of sodium/potassium ions suggests Na+-mediated generalized allostery is the mechanism of thrombin"s functional switch between the "fast" and "slow" forms.	Potassium	48-57	coagulation factor II, thrombin	Homo sapiens	13-21
28849814-10	2017	Our study of thrombin in the presence of sodium/potassium ions suggests Na+-mediated generalized allostery is the mechanism of thrombin"s functional switch between the "fast" and "slow" forms.	Potassium	48-57	coagulation factor II, thrombin	Homo sapiens	127-135
29955681-13	2017	These pasta patterns contribute in different ways to diet quality and intakes of fiber, sodium, and potassium.	Potassium	100-109	solute carrier family 45 member 1	Homo sapiens	6-11
28821664-9	2017	Prolonged activation of somatic MORs in POMC neurons robustly inhibited action potential firing and Ca2+ activity despite desensitization of the MOR and reduced activation of a potassium current over the same time course.	Potassium	177-186	pro-opiomelanocortin-alpha	Mus musculus	40-44
28877665-5	2017	As 14-3-3 proteins are key regulators of signal transduction processes, we investigated the effect of deletion of the 14-3-3 genes BMH1 or BMH2 on gene expression during potassium starvation and focused especially on the expression of genes involved in phosphate uptake.	Potassium	170-179	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	131-135
28552344-4	2017	ASP2905 potently inhibited potassium currents in CHO cells expressing KCNH3 (IC50 = 9.0nM).	Potassium	27-36	potassium voltage-gated channel subfamily H member 3	Cricetulus griseus	70-75
28821664-9	2017	Prolonged activation of somatic MORs in POMC neurons robustly inhibited action potential firing and Ca2+ activity despite desensitization of the MOR and reduced activation of a potassium current over the same time course.	Potassium	177-186	opioid receptor, mu 1	Mus musculus	32-35
28924484-6	2017	After starting insulin and rapid hemodialysis, the serum potassium level was normalized.	Potassium	57-66	insulin	Homo sapiens	15-22
27440776-0	2017	(Pro)Renin receptor regulates potassium homeostasis through a local mechanism.	Potassium	30-39	ATPase H+ transporting accessory protein 2	Rattus norvegicus	5-19
29031359-7	2017	Additionally, we discuss the role of new agents designed to bind potassium in the gastrointestinal tract that can be used to maintain normokalemia in patients who previously developed hyperkalemia on renin-angiotensin-aldosterone blockers.	Potassium	65-74	renin	Homo sapiens	200-205
28556923-2	2017	However, ivabradine also inhibits human ether-a-go-go (hERG) mediated potassium currents.	Potassium	70-79	ETS transcription factor ERG	Homo sapiens	55-59
28698302-9	2017	Interaction of CYP2J2 with DZ produced a type II binding spectrum with a Ks of 2.8 muM and the IC50 for loss of OHEB carboxylation activity was 0.18 muM.	Potassium	73-75	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	15-21
28833693-10	2017	An application of TGF-beta1 itself attenuated generation of action potentials, inhibited sodium current and potentiated potassium currents.	Potassium	120-129	transforming growth factor, beta 1	Rattus norvegicus	18-27
28926857-0	2017	The Amelioration of Insulin Resistance in Salt Loading Subjects by Potassium Supplementation is Associated with a Reduction in Plasma IL-17A Levels.	Potassium	67-76	insulin	Homo sapiens	20-27
28926857-0	2017	The Amelioration of Insulin Resistance in Salt Loading Subjects by Potassium Supplementation is Associated with a Reduction in Plasma IL-17A Levels.	Potassium	67-76	interleukin 17A	Homo sapiens	134-140
28926857-7	2017	Results Participants exhibited increased plasma insulin level, as well as progressed HOMA-IR, during a high-salt diet intervention, which potassium supplementation reversed.	Potassium	138-147	insulin	Homo sapiens	48-55
28926857-8	2017	Moreover, after salt loading, the plasma IL-17A concentrations increased significantly (4.2+-2.1 pg/mL to 9.7+-5.1 pg/mL; P&lt;0.01), whereas dropped considerably when dietary potassium was supplemented (9.7+-5.1 pg/mL to 2.0+-0.9 pg/mL; P&lt;0.001).	Potassium	176-185	interleukin 17A	Homo sapiens	41-47
28926857-9	2017	Statistically significant correlations were found between changes in HOMA-IR and changes in plasma IL-17A concentrations during the interventions (low- to high-salt: r=0.642, P&lt;0.01; high-salt to potassium supplementation: r=0.703, P&lt;0.01).	Potassium	199-208	interleukin 17A	Homo sapiens	99-105
28926857-11	2017	Conclusions The amelioration of salt-loading-induced IR by potassium supplementation in participants may be related to the reduction in plasma IL-17A concentration.	Potassium	59-68	interleukin 17A	Homo sapiens	143-149
28666963-9	2017	Overall, our results suggest that the replacement of a negatively charged residue with a positively charged lysine at position 283 in Kv1.1 causes a drop of potassium current that likely accounts for EA-1 symptoms in the heterozygous carrier.	Potassium	157-166	potassium voltage-gated channel subfamily A member 1	Homo sapiens	134-139
28614115-2	2017	Loss of function mutations in the NKCC2 gene cause urinary salt and potassium wasting, whereas excessive NKCC2 function has been linked to high blood pressure.	Potassium	68-77	solute carrier family 12 member 1	Homo sapiens	34-39
28666963-9	2017	Overall, our results suggest that the replacement of a negatively charged residue with a positively charged lysine at position 283 in Kv1.1 causes a drop of potassium current that likely accounts for EA-1 symptoms in the heterozygous carrier.	Potassium	157-166	potassium voltage-gated channel subfamily A member 1	Homo sapiens	200-204
28779175-2	2017	Potassium efflux and mitochondrial damage are both reported to mediate NLRP3 inflammasome activation, but the underlying, orchestrating signaling events are still unclear.	Potassium	0-9	NLR family pyrin domain containing 3	Homo sapiens	71-76
28771277-4	2017	At baseline, the prothrombin mutation group formed denser clots (Ks -12 %, p=0.0006) and had impaired fibrinolysis (CLT +14 %, p=0.004, and CLT-TAFI +13 %, p=0.03) compared with the no mutation group and were similar to those observed in 15 healthy unrelated prothrombin mutation carriers.	Potassium	65-67	coagulation factor II, thrombin	Homo sapiens	17-28
28861073-6	2017	Cells detect changes in potassium level as a Danger-associated molecular pattern associated with cell damage and induce BPI expression in a p38 dependent manner.	Potassium	24-33	bactericidal permeability increasing protein	Homo sapiens	120-123
28779175-3	2017	Here we show that chloride intracellular channels (CLIC) act downstream of the potassium efflux-mitochondrial reactive oxygen species (ROS) axis to promote NLRP3 inflammasome activation.	Potassium	79-88	NLR family pyrin domain containing 3	Homo sapiens	156-161
28779175-4	2017	NLRP3 agonists induce potassium efflux, which causes mitochondrial damage and ROS production.	Potassium	22-31	NLR family pyrin domain containing 3	Homo sapiens	0-5
28824688-0	2017	Induction of Barley Silicon Transporter HvLsi1 and HvLsi2, increased silicon concentration in the shoot and regulated Starch and ABA Homeostasis under Osmotic stress and Concomitant Potassium Deficiency.	Potassium	182-191	HvLsi1	Hordeum vulgare	40-46
28824688-0	2017	Induction of Barley Silicon Transporter HvLsi1 and HvLsi2, increased silicon concentration in the shoot and regulated Starch and ABA Homeostasis under Osmotic stress and Concomitant Potassium Deficiency.	Potassium	182-191	HvLsi2	Hordeum vulgare	51-57
28762967-8	2017	It also occurred that the potassium cation, quite uniformly coordinated by seven O atoms from all molecular fragments of the UMPH- anion, including the O atom from the ribofuranose ring, can be treated as spherical in the charge density model which was supported by theoretical calculations.	Potassium	26-35	5'-nucleotidase, cytosolic IIIA	Homo sapiens	125-129
28338826-6	2017	Ka/Ks ratios revealed that both chloroplast and nuclear rps16 copies were under purifying selection.	Potassium	3-5	ribosomal protein S16	Homo sapiens	56-61
28515174-1	2017	The thiazide-sensitive sodium chloride cotransporter NCC is important for maintaining serum sodium (Na+) and, indirectly, serum potassium (K+) levels.	Potassium	128-137	solute carrier family 12 member 3	Homo sapiens	53-56
28684627-6	2017	Depolarization with high extracellular potassium evokes Dpp release.	Potassium	39-48	decapentaplegic	Drosophila melanogaster	56-59
28289184-0	2017	Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.	Potassium	97-106	neural precursor cell expressed, developmentally down-regulated gene 4-like	Mus musculus	39-46
28657100-0	2017	Nanocrystalline SnS2 coated onto reduced graphene oxide: demonstrating the feasibility of a non-graphitic anode with sulfide chemistry for potassium-ion batteries.	Potassium	139-148	sodium voltage-gated channel alpha subunit 11	Homo sapiens	16-20
28233402-1	2017	KCNE1 is known to modulate the voltage-gated potassium channel alpha subunit KCNQ1 to generate slowly activating potassium currents.	Potassium	45-54	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	0-5
28233402-1	2017	KCNE1 is known to modulate the voltage-gated potassium channel alpha subunit KCNQ1 to generate slowly activating potassium currents.	Potassium	45-54	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	77-82
28389699-7	2017	This review will focus on the genetics of migraine with particular emphasis placed on the potentially important role genes HEPH (responsible for iron transport and homeostasis) and KCNK18 (important for the transport and homeostasis of potassium) play in migraine cause.	Potassium	236-245	hephaestin	Homo sapiens	123-127
28389699-7	2017	This review will focus on the genetics of migraine with particular emphasis placed on the potentially important role genes HEPH (responsible for iron transport and homeostasis) and KCNK18 (important for the transport and homeostasis of potassium) play in migraine cause.	Potassium	236-245	potassium two pore domain channel subfamily K member 18	Homo sapiens	181-187
28586097-7	2017	For example, two homologs of the MYB transcription factor genes MYB48 and MYB59 showed differential alternative splicing only in response to low levels of potassium.	Potassium	155-164	myb domain protein 48	Arabidopsis thaliana	64-69
28586097-7	2017	For example, two homologs of the MYB transcription factor genes MYB48 and MYB59 showed differential alternative splicing only in response to low levels of potassium.	Potassium	155-164	myb domain protein 59	Arabidopsis thaliana	74-79
28687778-4	2017	Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks values.	Potassium	147-149	infA	Panax ginseng	94-98
28687778-4	2017	Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks values.	Potassium	147-149	rpl22	Panax ginseng	100-105
28687778-4	2017	Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks values.	Potassium	147-149	rps19	Panax ginseng	107-112
28687778-4	2017	Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks values.	Potassium	216-218	infA	Panax ginseng	94-98
28687778-4	2017	Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks values.	Potassium	216-218	rps19	Panax ginseng	107-112
28469002-9	2017	Here, we demonstrate that NPY directly inhibited a subset of ventral tegmental area (VTA) dopamine neurons through the activation of G protein-coupled inwardly rectifying potassium currents, and it inhibited both excitatory postsynaptic currents and inhibitory postsynaptic currents onto subsets of dopamine neurons through a presynaptic mechanism.	Potassium	171-180	neuropeptide Y	Mus musculus	26-29
28620664-0	2017	Development of an RNA aptamer that acquires binding capacity against HIV-1 Tat protein via G-quadruplex formation in response to potassium ions.	Potassium	129-138	Tat	Human immunodeficiency virus 1	75-78
29744188-9	2017	An increase of extracellular potassium ions (K+) inhibited the secretion of IL-1ss and IL-18 (p = .008).	Potassium	29-38	interleukin 18	Homo sapiens	87-92
28395223-3	2017	Gamma spectrometric measurements were performed and it was dawn on the compounds which have low density, low molecular weight and high potassium abundance showed higher 40K activity concentration.	Potassium	135-144	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	169-172
28656556-10	2017	One observed the significant positive correlation of ACP with pH of soil and contents of potassium and magnesium and negative with contents of phosphorus and organic carbon.	Potassium	89-98	acid phosphatase	Zea mays	53-56
28398517-10	2017	Based on these studies, we propose that the chloride influx mediated by GlialCAM/MLC1/ClC-2 in astrocytes may be needed to compensate an excess of potassium, as occurs in conditions of high neuronal activity.	Potassium	147-156	hepatocyte cell adhesion molecule	Mus musculus	72-80
28398517-10	2017	Based on these studies, we propose that the chloride influx mediated by GlialCAM/MLC1/ClC-2 in astrocytes may be needed to compensate an excess of potassium, as occurs in conditions of high neuronal activity.	Potassium	147-156	megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)	Mus musculus	81-85
28398517-10	2017	Based on these studies, we propose that the chloride influx mediated by GlialCAM/MLC1/ClC-2 in astrocytes may be needed to compensate an excess of potassium, as occurs in conditions of high neuronal activity.	Potassium	147-156	chloride channel, voltage-sensitive 2	Mus musculus	86-91
28374413-5	2017	These beneficial effects of leptin involve restoration of action potential duration via normalization of transient outward potassium current and sarcoplasmic reticulum Ca2+ content via rescue of control sarcoplasmic/endoplasmic reticulum Ca2+ ATPase levels and ryanodine receptor function modulation, leading to normalization of Ca2+ handling parameters.	Potassium	123-132	leptin	Mus musculus	28-34
28461216-0	2017	Disruption of KV2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents.	Potassium	83-92	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	14-19
28558283-6	2017	Salt stress decreases the activities of antioxidant enzymes (superoxide dismutase, catalase and ascorbate peroxidase) while the exogenous application of potassium and zinc significantly enhanced the activities of these enzymes.	Potassium	153-162	catalase-1	Triticum aestivum	83-91
28558283-6	2017	Salt stress decreases the activities of antioxidant enzymes (superoxide dismutase, catalase and ascorbate peroxidase) while the exogenous application of potassium and zinc significantly enhanced the activities of these enzymes.	Potassium	153-162	peroxidase-like	Triticum aestivum	106-116
28600547-5	2017	Further, we tested the role of SUR1 in response to different potassium levels and found that dysfunction of SUR1 decreased the insulin secretion rate in low and high potassium environments.	Potassium	61-70	ATP binding cassette subfamily C member 8	Homo sapiens	31-35
28632755-7	2017	To confirm its importance we performed a series of in vitro experiments, in which we demonstrated that potassium levels a increased the virulence of the oral community as a whole and at the same time altering the immune response of gingival epithelium, increasing the production of TNF-alpha and reducing the expression of IL-6 and the antimicrobial peptide human beta-defensin 3 (hBD-3).	Potassium	103-112	tumor necrosis factor	Homo sapiens	282-291
28632755-7	2017	To confirm its importance we performed a series of in vitro experiments, in which we demonstrated that potassium levels a increased the virulence of the oral community as a whole and at the same time altering the immune response of gingival epithelium, increasing the production of TNF-alpha and reducing the expression of IL-6 and the antimicrobial peptide human beta-defensin 3 (hBD-3).	Potassium	103-112	interleukin 6	Homo sapiens	323-327
28632755-7	2017	To confirm its importance we performed a series of in vitro experiments, in which we demonstrated that potassium levels a increased the virulence of the oral community as a whole and at the same time altering the immune response of gingival epithelium, increasing the production of TNF-alpha and reducing the expression of IL-6 and the antimicrobial peptide human beta-defensin 3 (hBD-3).	Potassium	103-112	defensin beta 103B	Homo sapiens	364-379
28632755-7	2017	To confirm its importance we performed a series of in vitro experiments, in which we demonstrated that potassium levels a increased the virulence of the oral community as a whole and at the same time altering the immune response of gingival epithelium, increasing the production of TNF-alpha and reducing the expression of IL-6 and the antimicrobial peptide human beta-defensin 3 (hBD-3).	Potassium	103-112	defensin beta 103B	Homo sapiens	381-386
28600547-5	2017	Further, we tested the role of SUR1 in response to different potassium levels and found that dysfunction of SUR1 decreased the insulin secretion rate in low and high potassium environments.	Potassium	61-70	ATP binding cassette subfamily C member 8	Homo sapiens	108-112
28600547-5	2017	Further, we tested the role of SUR1 in response to different potassium levels and found that dysfunction of SUR1 decreased the insulin secretion rate in low and high potassium environments.	Potassium	166-175	ATP binding cassette subfamily C member 8	Homo sapiens	108-112
27913567-4	2017	We have identified the potassium-sparing diuretic drug triamterene, as a novel sensitizing agent in MMR-deficient tumor cells, in vitro and in vivoResults: The selective tumor cell cytotoxicity of triamterene occurs through its antifolate activity and depends on the activity of the folate synthesis enzyme thymidylate synthase.	Potassium	23-32	thymidylate synthetase	Homo sapiens	307-327
27927653-7	2017	Peak potassium currents were threefold higher in smooth muscle cells isolated from Af-arts or MCAs transfected with Add3 DsiRNA than in nontransfected cells isolated from the same vessels.	Potassium	5-14	adducin 3	Rattus norvegicus	116-120
28558783-3	2017	KS-IRIS was defined as &gt;=2 of the following: abrupt increase in number of KS lesions, appearance or exacerbation of lung-opacities or lymphedema, concomitantly with an increase in CD4+ cell-count &gt;=50 cells/mm3 and a decrease of &gt;1 log in viral-load once started cART.	Potassium	0-2	CD4 molecule	Homo sapiens	183-186
28322742-12	2017	In vivo electrophysiological intracellular recordings of individual spinal motoneurones revealed that central potassium channel function was preserved or even enhanced with higher amplitude and longer duration after-hyperpolarisations in the G127X SOD1 mice.	Potassium	110-119	superoxide dismutase 1, soluble	Mus musculus	248-252
28052988-0	2017	Potassium Sensing by Renal Distal Tubules Requires Kir4.1.	Potassium	0-9	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	51-57
28052988-5	2017	Here, we tested the hypothesis that the potassium channel Kir4.1 is the potassium sensor of DCT cells.	Potassium	40-49	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	58-64
28052988-7	2017	Deletion of Kir4.1 in these mice led to moderate salt wasting, low BP, and profound potassium wasting.	Potassium	84-93	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	12-18
28052988-10	2017	Together, these results indicate that Kir4.1 mediates potassium sensing by DCT cells and couples this signal to apical transport processes.	Potassium	54-63	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	38-44
28098344-4	2017	Moreover, we demonstrated that RXFP3 activation induces a cadmium-sensitive outward current, which indicates the involvement of a characteristic magnocellular neuron outward potassium current.	Potassium	174-183	relaxin family peptide receptor 3	Rattus norvegicus	31-36
28187982-0	2017	The renal TRPV4 channel is essential for adaptation to increased dietary potassium.	Potassium	73-82	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	10-15
28187982-4	2017	Here, we demonstrate that elevated dietary potassium intake (five percent potassium) increases renal TRPV4 mRNA and protein levels in an aldosterone-dependent manner and causes redistribution of the channel to the apical plasma membrane in native collecting duct cells.	Potassium	43-52	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	101-106
28187982-4	2017	Here, we demonstrate that elevated dietary potassium intake (five percent potassium) increases renal TRPV4 mRNA and protein levels in an aldosterone-dependent manner and causes redistribution of the channel to the apical plasma membrane in native collecting duct cells.	Potassium	74-83	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	101-106
28187982-5	2017	This, in turn, leads to augmented TRPV4-mediated flow-dependent calcium ion responses in freshly isolated split-opened collecting ducts from mice fed the high potassium diet.	Potassium	159-168	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	34-39
28187982-6	2017	Genetic TRPV4 ablation greatly diminished BK channel activity in collecting duct cells pointing to a reduced capacity to excrete potassium.	Potassium	129-138	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	8-13
28187982-7	2017	Consistently, elevated potassium intake induced hyperkalemia in TRPV4 knockout mice due to deficient renal potassium excretion.	Potassium	23-32	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	64-69
28187982-7	2017	Consistently, elevated potassium intake induced hyperkalemia in TRPV4 knockout mice due to deficient renal potassium excretion.	Potassium	107-116	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	64-69
28187982-8	2017	Thus, regulation of TRPV4 activity in the distal nephron by dietary potassium is an indispensable component of whole body potassium balance.	Potassium	68-77	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	20-25
28187982-8	2017	Thus, regulation of TRPV4 activity in the distal nephron by dietary potassium is an indispensable component of whole body potassium balance.	Potassium	122-131	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	20-25
28288868-2	2017	Particularly, Kir4.1 channels are involved in the astroglial spatial potassium buffering.	Potassium	69-78	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	14-20
28579824-4	2017	Here, using cultured DH neurons, we have shown that tumor necrosis factor-alpha inhibits the total outward potassium current IK and the KNa current predominantly as well as induces a progressive loss of firing accommodation.	Potassium	107-116	tumor necrosis factor	Rattus norvegicus	52-79
28596754-7	2017	In conclusion, mutant huntingtin-expressing cells showed a negligible effect of Ang II on potassium current, a result probably due to the reduced expression of AT1 receptors at the surface cell membrane.	Potassium	90-99	huntingtin	Mus musculus	22-32
28596754-8	2017	In contrast, administration of Ang (1-7) to the bath showed a significant decline of the potassium current in mutant cells, an effect dependent on the activation of Mas receptors.	Potassium	89-98	angiogenin, ribonuclease, RNase A family, 5	Mus musculus	31-34
28560099-8	2017	Moreover, the overall mean serum potassium concentration was significantly lower in the ACTH versus the non-ACTH group (3.34 mmol/L vs. 3.79 mmol/L, P = 0.001).	Potassium	33-42	proopiomelanocortin	Homo sapiens	88-92
28560099-8	2017	Moreover, the overall mean serum potassium concentration was significantly lower in the ACTH versus the non-ACTH group (3.34 mmol/L vs. 3.79 mmol/L, P = 0.001).	Potassium	33-42	proopiomelanocortin	Homo sapiens	108-112
28560099-10	2017	CONCLUSIONS: ACTH-pituitary adenomas may be an independent factor related postoperative hypokalemia in patients despite conventional potassium supplementation in the immediate postoperative period.	Potassium	133-142	proopiomelanocortin	Homo sapiens	13-17
28288868-7	2017	Overall, this study shows that quinacrine blocks Kir4.1 channels, which would be expected to impact the potassium transport in several tissues.	Potassium	104-113	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	49-55
28472061-3	2017	Ion currents from TRPM8 expressing trigeminal ganglion (TRG) neurons in females demonstrated larger hyperpolarization-activated cyclic nucleotide-gated currents (Ih) than male neurons at both 30  and 18 C. Additionally, female neurons" voltage gated potassium currents (Ik) were suppressed by cooling, whereas male Ik was not significantly affected.	Potassium	250-259	transient receptor potential cation channel, subfamily M, member 8	Mus musculus	18-23
28575882-11	2017	The ACE genotype correlated with QT dispersion, corrected QT dispersion, hemoglobin, and residual urine, and inversely correlated with serum potassium.	Potassium	141-150	angiotensin I converting enzyme	Homo sapiens	4-7
28094030-4	2017	Here we provide evidence supporting a role for GILZ in modulating the balance of renal sodium and potassium excretion by regulating the sodium-chloride cotransporter (NCC) activity in the distal nephron.	Potassium	98-107	TSC22 domain family, member 3	Mus musculus	47-51
28593901-8	2017	Sequence analysis of the CUL3 gene demonstrated a previously unreported heterozygous c.1377+2T&gt;3 mutation, confirming the diagnosis of PHAII-E. We highlight the importance of the determination of plasma aldosterone and plasma renin activity in the context of persistent sodium and potassium imbalances in children.	Potassium	284-293	cullin 3	Homo sapiens	25-29
28094030-5	2017	Gilz-/- mice have a higher plasma potassium concentration and lower fractional excretion of potassium than wild type mice.	Potassium	34-43	TSC22 domain family, member 3	Mus musculus	0-4
28094030-5	2017	Gilz-/- mice have a higher plasma potassium concentration and lower fractional excretion of potassium than wild type mice.	Potassium	92-101	TSC22 domain family, member 3	Mus musculus	0-4
28094030-11	2017	Thus, GILZ promotes potassium secretion by inhibiting NCC and enhancing distal sodium delivery to the epithelial sodium channel.	Potassium	20-29	TSC22 domain family, member 3	Mus musculus	6-10
27987209-0	2017	The sodium transporter encoded by the HKT1;2 gene modulates sodium/potassium homeostasis in tomato shoots under salinity.	Potassium	67-76	sodium transporter HKT1,2	Solanum lycopersicum	38-44
28457217-10	2017	A positive correlation was determined between the saliva fetuin-A levels and the saliva phosphorus and potassium levels of the patients ( P = .04, P = .02).	Potassium	103-112	alpha 2-HS glycoprotein	Homo sapiens	57-65
28420122-0	2017	The Effect of Salt Intake and Potassium Supplementation on Serum Gastrin Levels in Chinese Adults: A Randomized Trial.	Potassium	30-39	gastrin	Homo sapiens	65-72
28419159-12	2017	Compared to placebo, potassium supplementation resulted in modest but significant reductions in both SBP (MD -4.25 mmHg; 95% CI: -5.96 to -2.53; I2 = 41%) and DBP (MD -2.53 mmHg; 95% CI: -4.05 to -1.02; I2 = 65%).	Potassium	21-30	selenium binding protein 1	Homo sapiens	101-104
28419159-12	2017	Compared to placebo, potassium supplementation resulted in modest but significant reductions in both SBP (MD -4.25 mmHg; 95% CI: -5.96 to -2.53; I2 = 41%) and DBP (MD -2.53 mmHg; 95% CI: -4.05 to -1.02; I2 = 65%).	Potassium	21-30	D-box binding PAR bZIP transcription factor	Homo sapiens	159-162
28420122-4	2017	The aim of our study was to assess the effects of altered salt and potassium supplementation on serum gastrin levels in humans.	Potassium	67-76	gastrin	Homo sapiens	102-109
28420122-11	2017	The present study indicated that variations in dietary salt and potassium supplementation affected the serum gastrin concentrations in the Chinese subjects.	Potassium	64-73	gastrin	Homo sapiens	109-116
28218507-6	2017	The developed potassium ISE displays a wide linear sensing range (0.01-100 mM), a low detection limit (7 muM), minimal drift (8.6 x 10-6 V/s), and a negligible interference during electrochemical potassium sensing against the backdrop of interfering ions [i.e., sodium (Na), magnesium (Mg), and calcium (Ca)] and artificial eccrine perspiration.	Potassium	14-23	latexin	Homo sapiens	105-108
28298088-4	2017	Moreover, the potential signals of the IS-TGT for sodium and potassium ions, which are usually included in biological environments, were evaluated.	Potassium	61-70	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	42-45
28320163-0	2017	Inhibition of 17-beta-estradiol on neuronal excitability via enhancing GIRK1-mediated inwardly rectifying potassium currents and GIRK1 expression.	Potassium	106-115	potassium inwardly rectifying channel subfamily J member 3	Homo sapiens	71-76
27902841-8	2017	In cardiac myocytes, there are several Ca2+ -sensitive potassium (K+ ) currents such as the slowly activating delayed rectifier current (IKs ) and the small conductance Ca2+ -activated potassium (SK) current (ISK ).	Potassium	55-64	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	209-212
28185290-14	2017	This agreement holds for both loss-of-function and gain-of-function mutations in the HCN4, SCN5A and KCNQ1 genes, underlying ion channelopathies in If , fast sodium current and slow delayed rectifier potassium current, respectively.	Potassium	200-209	hyperpolarization activated cyclic nucleotide gated potassium channel 4	Homo sapiens	85-89
27997067-0	2017	Rotenone and elevated extracellular potassium concentration induce cell-specific fibrillation of alpha-synuclein in axons of cholinergic enteric neurons in the guinea-pig ileum.	Potassium	36-45	synuclein alpha	Homo sapiens	97-112
28164279-7	2017	Calcipotriol significantly decreased the frequency of alpha-synuclein aggregate positive cells subjected to treatments that cause raised intracellular-free Ca(II) (potassium depolarization, KCl/H2 O2 combined treatment, and rotenone) in a dose-dependent manner and increased viability.	Potassium	164-173	synuclein alpha	Homo sapiens	54-69
28131627-1	2017	Inward rectifying potassium - Kir - channels drive the resting potential to potassium reversal potential and, when disrupted, might be related to muscular diseases.	Potassium	18-27	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	30-33
28327612-5	2017	Postsynaptically, the opioids activate a potassium conductance through the mu-opioid receptor (MOR), suggesting for the first time that endogenously released opioids directly regulate neuronal excitability.	Potassium	41-50	opioid receptor mu 1	Homo sapiens	75-93
28327612-5	2017	Postsynaptically, the opioids activate a potassium conductance through the mu-opioid receptor (MOR), suggesting for the first time that endogenously released opioids directly regulate neuronal excitability.	Potassium	41-50	opioid receptor mu 1	Homo sapiens	95-98
28262710-1	2017	The distribution of potassium (K+) ions on air-cleaved mica is important in many interfacial phenomena such as crystal growth, self-assembly and charge transfer on mica.	Potassium	20-29	MHC class I polypeptide-related sequence A	Homo sapiens	55-59
28262710-1	2017	The distribution of potassium (K+) ions on air-cleaved mica is important in many interfacial phenomena such as crystal growth, self-assembly and charge transfer on mica.	Potassium	20-29	MHC class I polypeptide-related sequence A	Homo sapiens	164-168
28042949-6	2017	KS-IMM cells infected by Chi-H1/CXCL4L1 or Chi-H1/CXCL10 released the corresponding chemokine and showed reduced migratory capacity.	Potassium	0-2	platelet factor 4 variant 1	Homo sapiens	32-39
28273873-6	2017	CSK rs1378942 and CSK-MIR4513 rs3784789 were significantly modified by urinary sodium-potassium excretion ratio.	Potassium	86-95	C-terminal Src kinase	Homo sapiens	0-3
28273873-6	2017	CSK rs1378942 and CSK-MIR4513 rs3784789 were significantly modified by urinary sodium-potassium excretion ratio.	Potassium	86-95	C-terminal Src kinase	Homo sapiens	18-21
28273873-6	2017	CSK rs1378942 and CSK-MIR4513 rs3784789 were significantly modified by urinary sodium-potassium excretion ratio.	Potassium	86-95	microRNA 4513	Homo sapiens	22-29
28273873-8	2017	The present study results indicated that the mutant alleles of CSK rs1378942 and CSK-MIR4513 rs3784789 had the strongest protective effects against hypertension in the middle group of 24 h estimated urinary sodium-potassium excretion ratio.	Potassium	214-223	C-terminal Src kinase	Homo sapiens	63-66
28273873-8	2017	The present study results indicated that the mutant alleles of CSK rs1378942 and CSK-MIR4513 rs3784789 had the strongest protective effects against hypertension in the middle group of 24 h estimated urinary sodium-potassium excretion ratio.	Potassium	214-223	C-terminal Src kinase	Homo sapiens	81-84
28273873-8	2017	The present study results indicated that the mutant alleles of CSK rs1378942 and CSK-MIR4513 rs3784789 had the strongest protective effects against hypertension in the middle group of 24 h estimated urinary sodium-potassium excretion ratio.	Potassium	214-223	microRNA 4513	Homo sapiens	85-92
28122887-4	2017	Mutations in the anosmin-1 (ANOS1) gene are responsible for the X-linked recessive form of KS.	Potassium	91-93	anosmin 1	Homo sapiens	17-26
28122887-4	2017	Mutations in the anosmin-1 (ANOS1) gene are responsible for the X-linked recessive form of KS.	Potassium	91-93	anosmin 1	Homo sapiens	28-33
28042949-6	2017	KS-IMM cells infected by Chi-H1/CXCL4L1 or Chi-H1/CXCL10 released the corresponding chemokine and showed reduced migratory capacity.	Potassium	0-2	C-X-C motif chemokine ligand 10	Homo sapiens	50-56
28042949-10	2017	Further experiments indicated that CXCL4L1 and CXCL10 interfered with the expression of the viral NS1 protein in KS-IMM cells.	Potassium	113-115	platelet factor 4 variant 1	Homo sapiens	35-42
28042949-10	2017	Further experiments indicated that CXCL4L1 and CXCL10 interfered with the expression of the viral NS1 protein in KS-IMM cells.	Potassium	113-115	C-X-C motif chemokine ligand 10	Homo sapiens	47-53
28042949-10	2017	Further experiments indicated that CXCL4L1 and CXCL10 interfered with the expression of the viral NS1 protein in KS-IMM cells.	Potassium	113-115	influenza virus NS1A binding protein	Homo sapiens	98-101
28096356-4	2017	Here, we provide evidence that MLKL-induced activation of NLRP3 requires (i) the death effector four-helical bundle of MLKL, (ii) oligomerization and association of MLKL with cellular membranes, and (iii) a reduction in intracellular potassium concentration.	Potassium	234-243	mixed lineage kinase domain like pseudokinase	Homo sapiens	31-35
28130493-4	2017	MLKL activation triggers potassium efflux and assembly of the NLRP3 inflammasome, which is required for the processing and activity of IL-1beta released during necroptosis.	Potassium	25-34	mixed lineage kinase domain like pseudokinase	Homo sapiens	0-4
28130493-4	2017	MLKL activation triggers potassium efflux and assembly of the NLRP3 inflammasome, which is required for the processing and activity of IL-1beta released during necroptosis.	Potassium	25-34	interleukin 1 beta	Homo sapiens	135-143
28012096-1	2017	The voltage gated sodium channel SCN4A mutations account for non-dystrophic myotonia and include a heterogeneous group of conditions that include hyperkalemic periodic paralysis, paramyotonica congenita, potassium-aggravated myotonia, and hypokalemic periodic paralysis type 2.	Potassium	204-213	sodium voltage-gated channel alpha subunit 4	Homo sapiens	33-38
27856205-8	2017	These results suggest that upregulation of the ROMK channel in apical cells might permit avid potassium flux into the bladder lumen to maintain intracellular K+ homeostasis in the dysfunctional urothelium.	Potassium	94-103	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	47-51
27939864-2	2017	Serum potassium should be investigated in patients developing chronic or frequent vomiting or diarrhea, marked polyuria, muscle weakness, or unexpected cardiac arrhythmias, as well as in those undergoing therapy with insulin, diuretics, or total parenteral nutrition.	Potassium	6-15	insulin	Homo sapiens	217-224
28119399-8	2017	The effect of cross-linked 300 kDa on potassium current was reduced by removing Na+ from the bath solution, or by knocking down levels of Slack using siRNA.	Potassium	38-47	slack	Aplysia californica	138-143
28193246-4	2017	The same KvLQT1/KCNE1 channel complex is expressed in the inner ear and essential for luminal potassium secretion into the endolymphatic space.	Potassium	94-103	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	9-15
28193246-4	2017	The same KvLQT1/KCNE1 channel complex is expressed in the inner ear and essential for luminal potassium secretion into the endolymphatic space.	Potassium	94-103	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	16-21
28096356-4	2017	Here, we provide evidence that MLKL-induced activation of NLRP3 requires (i) the death effector four-helical bundle of MLKL, (ii) oligomerization and association of MLKL with cellular membranes, and (iii) a reduction in intracellular potassium concentration.	Potassium	234-243	NLR family pyrin domain containing 3	Homo sapiens	58-63
28096356-4	2017	Here, we provide evidence that MLKL-induced activation of NLRP3 requires (i) the death effector four-helical bundle of MLKL, (ii) oligomerization and association of MLKL with cellular membranes, and (iii) a reduction in intracellular potassium concentration.	Potassium	234-243	mixed lineage kinase domain like pseudokinase	Homo sapiens	119-123
28096356-4	2017	Here, we provide evidence that MLKL-induced activation of NLRP3 requires (i) the death effector four-helical bundle of MLKL, (ii) oligomerization and association of MLKL with cellular membranes, and (iii) a reduction in intracellular potassium concentration.	Potassium	234-243	mixed lineage kinase domain like pseudokinase	Homo sapiens	119-123
27506492-3	2017	Here we show that LPS application to hippocampal slices markedly enhances the excitability of CA1 pyramidal cells by inhibiting a specific potassium current, the M-current, generated by KV 7/M channels, which controls the excitability of almost every neuron in the CNS.	Potassium	139-148	carbonic anhydrase 1	Homo sapiens	94-97
27842238-1	2017	Classical modes of NLRP3 activation entail a priming step that enables its activation (signal 1) and a potassium efflux-dependent activation signal (signal 2) that triggers pyroptosome formation and pyroptosis, a lytic cell death necessary for IL-1beta release.	Potassium	103-112	NLR family pyrin domain containing 3	Homo sapiens	19-24
27835032-10	2017	After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake.	Potassium	342-351	selenium binding protein 1	Homo sapiens	32-35
27920129-1	2017	The renal outer medullary potassium (ROMK) channel mediates potassium recycling and facilitates sodium reabsorption through the Na+/K+/2Cl- cotransporter in the loop of Henle and potassium secretion at the cortical collecting duct.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	37-41
27562026-1	2017	KEY POINTS: Kv2 channels underlie delayed-rectifier potassium currents in various neurons, although their physiological roles often remain elusive.	Potassium	52-61	potassium voltage-gated channel subfamily A member 6	Rattus norvegicus	12-15
28135564-4	2017	The accumulation of extremely large amounts of GFAP causes many molecular changes in astrocytes, including proteasome inhibition, stress kinase activation, mechanistic target of rapamycin (mTOR) activation, loss of glutamate and potassium buffering capacity, loss of astrocyte coupling, and changes in cell morphology.	Potassium	229-238	glial fibrillary acidic protein	Homo sapiens	47-51
28321294-11	2017	Moreover, this study confirms the importance of potassium dosage when screening the renin-angiotensin-aldosterone system.	Potassium	48-57	renin	Homo sapiens	84-89
28017718-0	2017	Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2).	Potassium	79-88	amyloid beta precursor protein	Rattus norvegicus	33-58
28017718-0	2017	Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2).	Potassium	79-88	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Rattus norvegicus	163-167
28017718-4	2017	Interestingly, one of the purified proteins was potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2), which has been shown to be involved in epilepsy.	Potassium	48-57	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Rattus norvegicus	132-136
28073850-1	2017	BACKGROUND: Heart failure guidelines recommend routine monitoring of serum potassium, and renal function in patients treated with a mineralocorticoid receptor antagonist (MRA).	Potassium	75-84	nuclear receptor subfamily 3 group C member 2	Homo sapiens	132-158
27895122-2	2017	Among the major determinants of potassium uptake in the model organism Saccharomyces cerevisiae are the Trk1 high affinity potassium transporter and the functionally redundant Hal4 (Sat4) and Hal5 protein kinases.	Potassium	32-41	Trk1p	Saccharomyces cerevisiae S288C	104-108
27895122-2	2017	Among the major determinants of potassium uptake in the model organism Saccharomyces cerevisiae are the Trk1 high affinity potassium transporter and the functionally redundant Hal4 (Sat4) and Hal5 protein kinases.	Potassium	32-41	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	176-180
27895122-2	2017	Among the major determinants of potassium uptake in the model organism Saccharomyces cerevisiae are the Trk1 high affinity potassium transporter and the functionally redundant Hal4 (Sat4) and Hal5 protein kinases.	Potassium	32-41	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	182-186
27895122-2	2017	Among the major determinants of potassium uptake in the model organism Saccharomyces cerevisiae are the Trk1 high affinity potassium transporter and the functionally redundant Hal4 (Sat4) and Hal5 protein kinases.	Potassium	32-41	protein kinase HAL5	Saccharomyces cerevisiae S288C	192-196
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	36-45	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	71-75
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	36-45	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	111-115
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	36-45	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	117-121
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	36-45	protein kinase HAL5	Saccharomyces cerevisiae S288C	122-126
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	36-45	Trk1p	Saccharomyces cerevisiae S288C	131-135
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	36-45	Trk2p	Saccharomyces cerevisiae S288C	136-140
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	231-240	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	71-75
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	231-240	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	111-115
27895122-6	2017	Specifically, growth under limiting potassium alters the activities of Npr1 and another TORC1 effector kinase, Sch9; hal4 hal5 and trk1 trk2 mutants display hypersensitivity to rapamycin, and reciprocally, TORC1 inhibition reduces potassium accumulation.	Potassium	231-240	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	117-121
28164127-5	2017	The apical membrane expression, where NKCC2 is functional, may be sufficient to normalize water, potassium, sodium, and osmolytes tubular handling.	Potassium	97-106	solute carrier family 12 member 1	Rattus norvegicus	38-43
29115510-10	2018	Therefore, HGF may be important in potassium excretion and perform antihyperkalemic effects through the translocation of potassium channels.	Potassium	35-44	hepatocyte growth factor	Rattus norvegicus	11-14
27823598-8	2017	Patients with high potassium more often used angiotensin-converting enzyme inhibitors and mineralocorticoid receptor antagonists before admission, had impaired baseline renal function and a better diuretic response (p = 0.005), independent of mineralocorticoid receptor antagonist usage.	Potassium	19-28	nuclear receptor subfamily 3 group C member 2	Homo sapiens	90-116
27823598-8	2017	Patients with high potassium more often used angiotensin-converting enzyme inhibitors and mineralocorticoid receptor antagonists before admission, had impaired baseline renal function and a better diuretic response (p = 0.005), independent of mineralocorticoid receptor antagonist usage.	Potassium	19-28	nuclear receptor subfamily 3 group C member 2	Homo sapiens	243-269
28158516-1	2017	Aims: Diuretics and renin-angiotensin-aldosterone system inhibitors are central in the treatment of hypertension, but may cause serum potassium abnormalities.	Potassium	134-143	renin	Homo sapiens	20-25
28551790-3	2017	Apart from its localization at the plasma membrane, Cx43 is also present in cardiomyocyte mitochondria, where it is important for mitochondrial function in terms of oxygen consumption and potassium fluxes.	Potassium	188-197	gap junction protein alpha 1	Homo sapiens	52-56
28164127-8	2017	These data suggest that the upregulation in the expression of NKCC2 in apical membranes during the postobstructive phase of BUO could contribute to improving the excretion of sodium and consequently also the excretion of potassium, osmolytes, and water.	Potassium	221-230	solute carrier family 12 member 1	Rattus norvegicus	62-67
27816553-3	2017	Additionally, OAA inhibited serum and potassium deprivation-induced caspase 3 activation.	Potassium	38-47	caspase 3	Homo sapiens	68-77
27830577-6	2017	Orexin peptides excite other arousal-promoting neurons (noradrenaline, histamine, serotonin, acetylcholine neurons), either by activating mixed-cation conductances or by inhibiting potassium conductances.	Potassium	181-190	hypocretin neuropeptide precursor	Homo sapiens	0-6
28714415-3	2017	The interactions of AQP4 are as follows: (i) AQP4 could influence astrocytic calcium signaling and potassium homeostasis.	Potassium	99-108	aquaporin 4	Homo sapiens	20-24
28714415-3	2017	The interactions of AQP4 are as follows: (i) AQP4 could influence astrocytic calcium signaling and potassium homeostasis.	Potassium	99-108	aquaporin 4	Homo sapiens	45-49
27147508-6	2017	There were increased caspase -3, -8 and -9 activities when fibroblasts were treated with 0.4, 0.8 and 1.6 muM CdCl2 for 24 h. Higher intracellular calcium (Ca2+) and reactive oxygen species (ROS) levels, and enhanced efflux of extracellular Ca2+ and potassium (K+).	Potassium	250-259	caspase 3	Mus musculus	21-42
28286812-0	2017	20-Day Trend of Serum Potassium Changes in Bam Earthquake Victims with Crush Syndrome; a Cross-sectional Study.	Potassium	22-31	structural maintenance of chromosomes 3	Homo sapiens	43-46
28286812-2	2017	The present study aimed to evaluate the trend of potassium changes in crush syndrome patients of Bam earthquake.	Potassium	49-58	structural maintenance of chromosomes 3	Homo sapiens	97-100
28286812-3	2017	METHODS: In this retrospective cross-sectional study, using the database of Bam earthquake victims, which were developed by Iranian Society of Nephrology following Bam earthquake, Iran, 2003, the 20-day trend of potassium changes in &gt; 15 years old crush syndrome patients was evaluated.	Potassium	212-221	structural maintenance of chromosomes 3	Homo sapiens	76-79
28286812-3	2017	METHODS: In this retrospective cross-sectional study, using the database of Bam earthquake victims, which were developed by Iranian Society of Nephrology following Bam earthquake, Iran, 2003, the 20-day trend of potassium changes in &gt; 15 years old crush syndrome patients was evaluated.	Potassium	212-221	structural maintenance of chromosomes 3	Homo sapiens	164-167
28177101-9	2017	Serum potassium values were significantly higher in patients treated with both ACE/ARB and antialdosterone drugs.	Potassium	6-15	angiotensin I converting enzyme	Homo sapiens	79-82
27481527-1	2017	Connexin 26 (Cx-26), a gap junction protein coded by GJB2 gene, plays a very important role in recycling of potassium ions, one of the vital steps in the mechanotransduction process of hearing.	Potassium	108-117	gap junction protein beta 2	Homo sapiens	0-11
27481527-1	2017	Connexin 26 (Cx-26), a gap junction protein coded by GJB2 gene, plays a very important role in recycling of potassium ions, one of the vital steps in the mechanotransduction process of hearing.	Potassium	108-117	gap junction protein beta 2	Homo sapiens	13-18
27481527-1	2017	Connexin 26 (Cx-26), a gap junction protein coded by GJB2 gene, plays a very important role in recycling of potassium ions, one of the vital steps in the mechanotransduction process of hearing.	Potassium	108-117	gap junction protein beta 2	Homo sapiens	53-57
27381844-8	2017	Plasma potassium concentration strongly and negatively correlated with pNCC, NCC, and WNK4 abundance (P&lt;0.001 for all).	Potassium	7-16	WNK lysine deficient protein kinase 4	Homo sapiens	86-90
28367274-0	2017	Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons.	Potassium	34-43	AKT serine/threonine kinase 1	Homo sapiens	85-88
28367274-0	2017	Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons.	Potassium	34-43	thioredoxin interacting protein	Homo sapiens	118-123
27966362-1	2016	Na+/K+-ATPase (NKA) is an essential cation pump protein responsible for the maintenance of the sodium and potassium gradients across the plasma membrane.	Potassium	106-115	tachykinin precursor 1	Homo sapiens	0-13
27867157-4	2016	Our study was designed to examine the effects of salt intake and potassium supplementation on plasma OPG levels in normotensive subjects.Methods and Results:The 18 normotensive subjects were selected from a rural community in China.	Potassium	65-74	TNF receptor superfamily member 11b	Homo sapiens	101-104
27867157-9	2016	By contrast, OPG concentration negatively correlated with 24-h urinary potassium excretion (r=0.594, P&lt;0.01).	Potassium	71-80	TNF receptor superfamily member 11b	Homo sapiens	13-16
27867157-11	2016	Potassium supplementation can reverse the effects of excessive OPG.	Potassium	0-9	TNF receptor superfamily member 11b	Homo sapiens	63-66
27789381-2	2016	The TWIK-related spinal cord K+ (TRESK) is the major background potassium current in dorsal root ganglia (DRG), we found that mitogen-activated protein kinase (MAPK) signal pathway were activated in spinal cord accompanied by TRESK down regulation in response to NP.	Potassium	64-73	potassium two pore domain channel subfamily K member 1	Rattus norvegicus	4-8
27960436-7	2016	As the degree of PDI aggregation was reduced, ks,opt declined, which is attributed to a reduction in the lateral electron self-exchange rate between adsorbed PDI molecules, as well as the heterogeneous conductivity of the ITO electrode surface.	Potassium	46-48	peptidyl arginine deiminase 1	Homo sapiens	17-20
27960436-7	2016	As the degree of PDI aggregation was reduced, ks,opt declined, which is attributed to a reduction in the lateral electron self-exchange rate between adsorbed PDI molecules, as well as the heterogeneous conductivity of the ITO electrode surface.	Potassium	46-48	peptidyl arginine deiminase 1	Homo sapiens	158-161
27924824-4	2016	Potassium uptake from the rhizosphere is mediated mainly by KUP/HAK/KT and CNGC transporters.	Potassium	0-9	zinc finger and BTB domain containing 25	Homo sapiens	60-63
27924824-4	2016	Potassium uptake from the rhizosphere is mediated mainly by KUP/HAK/KT and CNGC transporters.	Potassium	0-9	alpha kinase 2	Homo sapiens	64-67
28006004-6	2016	Inhibition of Na+/K+ ATPase by an alternative approach (removal of extracellular potassium) had a similar effect in HLF.	Potassium	81-90	HLF transcription factor, PAR bZIP family member	Homo sapiens	116-119
28003811-10	2016	The association of potassium with risk of CD and UC appeared to be modified by loci involved in the TH17 pathway that have previously been associated with susceptibility to CD, particularly SNP rs7657746 (IL21) (Pinteraction = 0.004 and 0.01, respectively).	Potassium	19-28	interleukin 21	Homo sapiens	205-209
27966362-1	2016	Na+/K+-ATPase (NKA) is an essential cation pump protein responsible for the maintenance of the sodium and potassium gradients across the plasma membrane.	Potassium	106-115	tachykinin precursor 1	Homo sapiens	15-18
28003811-11	2016	In vitro, potassium enhanced the expression of Foxp3 in both naive and memory CD4+ T cells via activating Smad2/3 and inhibiting Smad7 in TH17 cells.	Potassium	10-19	forkhead box P3	Homo sapiens	47-52
28003811-11	2016	In vitro, potassium enhanced the expression of Foxp3 in both naive and memory CD4+ T cells via activating Smad2/3 and inhibiting Smad7 in TH17 cells.	Potassium	10-19	SMAD family member 2	Homo sapiens	106-113
27756725-4	2016	Insulin and beta-adrenergic tone play critical roles in maintaining the internal distribution of potassium under normal conditions.	Potassium	97-106	insulin	Homo sapiens	0-7
28003811-11	2016	In vitro, potassium enhanced the expression of Foxp3 in both naive and memory CD4+ T cells via activating Smad2/3 and inhibiting Smad7 in TH17 cells.	Potassium	10-19	SMAD family member 7	Homo sapiens	129-134
27492348-3	2016	Within the QTL SI regions, 44 genes were located, and runt-related transcription factor 1, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), and potassium inwardly-rectifying channel, subfamily J, member 15 KCNJ15-which are reported to be related to the hematological traits and clinical features of Down syndrome-were selected as positional candidate genes.	Potassium	171-180	potassium inwardly rectifying channel subfamily J member 15	Sus scrofa	233-239
27599629-6	2016	In patients with DKA and a relatively low plasma potassium level, insulin administration may cause hypokalemia and cardiac arrhythmias.	Potassium	49-58	insulin	Homo sapiens	66-73
27895227-0	2016	Phosphorylation of ARF2 Relieves Its Repression of Transcription of the K+ Transporter Gene HAK5 in Response to Low Potassium Stress.	Potassium	116-125	auxin response factor 2	Arabidopsis thaliana	19-23
27895227-0	2016	Phosphorylation of ARF2 Relieves Its Repression of Transcription of the K+ Transporter Gene HAK5 in Response to Low Potassium Stress.	Potassium	116-125	high affinity K+ transporter 5	Arabidopsis thaliana	92-96
28097003-6	2016	System-specific maximal achievable Delta QTc was estimated to 28% from baseline in both dog and human, while %hERG block leading to half-maximal effects was 58% lower in human, suggesting a higher contribution of hERG-mediated potassium current to cardiac repolarization.	Potassium	227-236	ETS transcription factor ERG	Homo sapiens	213-217
27882934-4	2016	IL-1beta causes prolongation of the action potential duration, induces a decrease in potassium current and an increase in calcium sparks in cardiomyocytes, which are changes that underlie arrhythmia propensity.	Potassium	85-94	interleukin 1 beta	Mus musculus	0-8
27852771-3	2016	KCC2 regulates intraneuronal chloride and extracellular potassium levels by extruding both ions.	Potassium	56-65	solute carrier family 12 member 5	Homo sapiens	0-4
27609046-10	2016	Considering evidence from brain ischemia models, KCNK10/TREK-2 upregulation might serve a protective function with a beneficial impact on astrocytic potassium and glutamate homeostasis.	Potassium	149-158	potassium two pore domain channel subfamily K member 10	Rattus norvegicus	49-55
27609046-10	2016	Considering evidence from brain ischemia models, KCNK10/TREK-2 upregulation might serve a protective function with a beneficial impact on astrocytic potassium and glutamate homeostasis.	Potassium	149-158	potassium two pore domain channel subfamily K member 10	Rattus norvegicus	56-62
27852771-4	2016	Absence of effective KCC2 may alter the dynamics of chloride and potassium levels during repeated activation of GABAergic synapses due to interneuron activity.	Potassium	65-74	solute carrier family 12 member 5	Homo sapiens	21-25
27852771-9	2016	The pyramidal cell model explicitly incorporated the cotransporter KCC2 and its effects on the internal/external chloride and potassium levels.	Potassium	126-135	solute carrier family 12 member 5	Homo sapiens	67-71
27852771-10	2016	Our network model suggested the loss of KCC2 in a critical number of pyramidal cells increased external potassium and intracellular chloride concentrations leading to seizure-like field potential oscillations.	Potassium	104-113	solute carrier family 12 member 5	Homo sapiens	40-44
27895596-1	2016	The inwardly rectifying potassium current (IK1) and the fast inward sodium current (INa) are reciprocally modulated in mammalian ventricular myocytes.	Potassium	24-33	IKAROS family zinc finger 1	Homo sapiens	43-46
27895596-6	2016	The conductances, GK1, of the inwardly rectifying potassium current, and GNa, of the fast inward sodium current were modified independently and in tandem to simulate reciprocal modulation.	Potassium	50-59	glycerol kinase	Homo sapiens	18-21
27895596-12	2016	Reciprocal modulation of the inwardly rectifying potassium current and the fast inward sodium current may have a functional role in allowing cardiac tissue to remain excitable when IK1 is upregulated.	Potassium	49-58	IKAROS family zinc finger 1	Homo sapiens	181-184
27566292-6	2016	In contrast, knockdown of endogenous THIK-1 by RNA interference resulted in delayed shrinkage and potassium efflux.	Potassium	98-107	potassium channel, two pore domain subfamily K, member 13 S homeolog	Xenopus laevis	37-43
27829152-0	2016	A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism.	Potassium	8-17	agouti related neuropeptide	Mus musculus	29-33
27829152-0	2016	A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism.	Potassium	8-17	neuropeptide Y	Mus musculus	34-37
27829152-4	2016	We found that AgRP/NPY neurons in satiated mice express high levels of the small-conductance calcium-activated potassium channel 3 (SK3) and are inhibited by SK3-mediated potassium currents; on the other hand, food deprivation suppresses SK3 expression in AgRP/NPY neurons, and the decreased SK3-mediated currents contribute to fasting-induced activation of these neurons.	Potassium	111-120	agouti related neuropeptide	Mus musculus	14-18
27829152-4	2016	We found that AgRP/NPY neurons in satiated mice express high levels of the small-conductance calcium-activated potassium channel 3 (SK3) and are inhibited by SK3-mediated potassium currents; on the other hand, food deprivation suppresses SK3 expression in AgRP/NPY neurons, and the decreased SK3-mediated currents contribute to fasting-induced activation of these neurons.	Potassium	111-120	neuropeptide Y	Mus musculus	19-22
27829152-4	2016	We found that AgRP/NPY neurons in satiated mice express high levels of the small-conductance calcium-activated potassium channel 3 (SK3) and are inhibited by SK3-mediated potassium currents; on the other hand, food deprivation suppresses SK3 expression in AgRP/NPY neurons, and the decreased SK3-mediated currents contribute to fasting-induced activation of these neurons.	Potassium	111-120	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	Mus musculus	132-135
27829152-4	2016	We found that AgRP/NPY neurons in satiated mice express high levels of the small-conductance calcium-activated potassium channel 3 (SK3) and are inhibited by SK3-mediated potassium currents; on the other hand, food deprivation suppresses SK3 expression in AgRP/NPY neurons, and the decreased SK3-mediated currents contribute to fasting-induced activation of these neurons.	Potassium	111-120	agouti related neuropeptide	Mus musculus	256-260
27829152-4	2016	We found that AgRP/NPY neurons in satiated mice express high levels of the small-conductance calcium-activated potassium channel 3 (SK3) and are inhibited by SK3-mediated potassium currents; on the other hand, food deprivation suppresses SK3 expression in AgRP/NPY neurons, and the decreased SK3-mediated currents contribute to fasting-induced activation of these neurons.	Potassium	111-120	neuropeptide Y	Mus musculus	261-264
27942049-0	2016	Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3.	Potassium	0-9	solute carrier family 12, member 3	Mus musculus	31-50
27942049-0	2016	Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3.	Potassium	0-9	kelch-like 3	Mus musculus	112-124
27843308-6	2016	Low intake of nutrients, including potassium, vitamin A, carotene, retinol, and vitamin C, was significantly associated with COPD.	Potassium	35-44	COPD	Homo sapiens	125-129
27508897-5	2016	Insulin treatment increased Ks and mitochondrial protein synthesis, enhanced translation activation, and reduced SIRT1 in CON.	Potassium	28-30	insulin	Sus scrofa	0-7
27508897-6	2016	In contrast, in CLP, insulin treatment increased Ks, protein kinase B (PKB) and Forkhead box O1 phosphorylation, antagonized AMPK activation, and decreased peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha), MuRF1, and SIRT1.	Potassium	49-51	insulin	Sus scrofa	21-28
27590241-4	2016	The increment of action potential duration caused by Ang-(1-12) (100 nM) was due to a decrease of total potassium current recorded from single cardiomyocytes using the whole cell configuration of pCAMP.	Potassium	104-113	angiogenin	Rattus norvegicus	53-56
27590241-5	2016	The decrease of potassium current was related to the activation of protein kinase C (PKC) because the specific inhibitor of kinase C, Bis-1 (10-9 M), abolished Ang-(1-12) effects on the potassium current.	Potassium	16-25	angiogenin	Rattus norvegicus	160-163
27590241-5	2016	The decrease of potassium current was related to the activation of protein kinase C (PKC) because the specific inhibitor of kinase C, Bis-1 (10-9 M), abolished Ang-(1-12) effects on the potassium current.	Potassium	186-195	angiogenin	Rattus norvegicus	160-163
27590241-7	2016	Moreover, intracellular Ang II (100 nM), by itself, reduced the potassium current, an effect decreased by intracellular valsartan (100 nM).	Potassium	64-73	angiogenin	Rattus norvegicus	24-27
27590241-9	2016	These observations demonstrate that the effect of Ang-(1-12) on potassium current was related to the formation of Ang II and that the peptide has arrhythmogenic properties.	Potassium	64-73	angiogenin	Rattus norvegicus	50-53
27590241-9	2016	These observations demonstrate that the effect of Ang-(1-12) on potassium current was related to the formation of Ang II and that the peptide has arrhythmogenic properties.	Potassium	64-73	angiogenin	Rattus norvegicus	114-117
27798188-1	2016	The delayed rectifier potassium (K+) channel KCNB1 (Kv2.1), which conducts a major somatodendritic current in cortex and hippocampus, is known to undergo oxidation in the brain, but whether this can cause neurodegeneration and cognitive impairment is not known.	Potassium	22-31	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	45-50
27798188-1	2016	The delayed rectifier potassium (K+) channel KCNB1 (Kv2.1), which conducts a major somatodendritic current in cortex and hippocampus, is known to undergo oxidation in the brain, but whether this can cause neurodegeneration and cognitive impairment is not known.	Potassium	22-31	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	52-57
27779191-4	2016	Intriguingly, 25-HC, but not VLCFA, promotes robust NLRP3 inflammasome assembly and activation via potassium efflux-, mitochondrial reactive oxygen species (ROS)- and liver X receptor (LXR)-mediated pathways.	Potassium	99-108	NLR family pyrin domain containing 3	Homo sapiens	52-57
27173557-3	2016	The results indicated that beta-lactoglobulin complexed with MG mainly via hydrophobic interaction with KS of 0.67x10(3)M(-)(1) at 297K.	Potassium	104-106	beta-lactoglobulin	Bos taurus	27-45
27534754-0	2016	High potassium promotes mutual interaction between (pro)renin receptor and the local renin-angiotensin-aldosterone system in rat inner medullary collecting duct cells.	Potassium	5-14	ATPase H+ transporting accessory protein 2	Rattus norvegicus	56-70
27725978-4	2016	To this end, we explored using first-principles calculations the strategy of doping of STO at the Sr site with sodium and potassium.	Potassium	122-131	nuclear receptor binding SET domain protein 1	Homo sapiens	87-90
27448328-5	2016	A new AED called retigabine increases potassium efflux by changing the conformation of KCNQ 2-5 potassium channels, which leads to neuronal hyperpolarisation and a decrease in excitability.	Potassium	38-47	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	87-93
27668019-1	2016	Experiments on hippocampal slices have recorded that a novel pattern of epileptic seizures with alternating excitatory and inhibitory activities in the CA1 region can be induced by an elevated potassium ion (K(+)) concentration in the extracellular space between neurons and astrocytes (ECS-NA).	Potassium	193-202	carbonic anhydrase 1	Homo sapiens	152-155
27558578-9	2016	In early lactation, multiple linear regressions showed that PC1 (calcium, magnesium, potassium, rubidium, and strontium intakes) was positively associated with WAZ, LAZ, and HCAZ.	Potassium	85-94	polycystin 1, transient receptor potential channel interacting	Homo sapiens	60-63
27600183-0	2016	Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension.	Potassium	0-9	angiotensinogen	Rattus norvegicus	84-98
28002912-6	2016	N-terminal propeptide of type I procollagen (PINP) correlated with 24-h excretion of potassium, calcium and citrate.	Potassium	85-94	collagen type I alpha 2 chain	Homo sapiens	25-43
26856345-5	2016	Patiromer has been found to decrease serum potassium in patients with hyperkalemia having chronic kidney disease who were on renin-angiotensin-aldosterone system inhibitors.	Potassium	43-52	renin	Homo sapiens	125-130
27432892-1	2016	The renal outer medullary potassium (ROMK) channel, located at the apical surface of epithelial cells in the thick ascending loop of Henle and cortical collecting duct, contributes to salt reabsorption and potassium secretion, and represents a target for the development of new mechanism of action diuretics.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	37-41
30193436-4	2016	In contrast to analogs of neurohypophysial nonapeptides, glucagon-like peptide-1 mimetic (exenatide) did not exert its physiological effects after oral administration, whereas it increased urinary sodium and potassium excretion following intramuscular injection.	Potassium	208-217	glucagon	Rattus norvegicus	57-80
29726164-6	2016	Catalase activity increased with the soil layer deepening, which was directly related to soil total potassium, and indirectly related to pH, organic matter, total nitrogen and total phosphorus through total potassium.	Potassium	100-109	catalase	Homo sapiens	0-8
29726164-6	2016	Catalase activity increased with the soil layer deepening, which was directly related to soil total potassium, and indirectly related to pH, organic matter, total nitrogen and total phosphorus through total potassium.	Potassium	207-216	catalase	Homo sapiens	0-8
27568555-3	2016	Specifically, our data reveal that Kv1 channels containing Kv1.3 subunits contribute significantly to the orphan potassium current known as IsAHP in striatal cholinergic interneurons.	Potassium	113-122	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	59-64
27322883-8	2016	Modulation of WNK4 by [Cl]i has been shown to account for the potassium-sensing properties of the distal convoluted tubule.	Potassium	62-71	WNK lysine deficient protein kinase 4	Homo sapiens	14-18
27322883-10	2016	SUMMARY: Modulation of WNK4 activity by [Cl]i can account for its dual role on the NCC, and this has important physiological implications regarding the regulation of extracellular potassium concentration.	Potassium	180-189	WNK lysine deficient protein kinase 4	Homo sapiens	23-27
26433375-7	2016	In addition, AQP4 may influence potassium (K(+)) and calcium (Ca(2+)) ion transport, which could play decisive roles in the pathogenesis of AD.	Potassium	32-41	aquaporin 4	Homo sapiens	13-17
27626381-4	2016	Elevation of the extracellular potassium concentration ([K+]e) impairs T cell receptor (TCR)-driven Akt-mTOR phosphorylation and effector programmes.	Potassium	31-40	thymoma viral proto-oncogene 1	Mus musculus	100-103
27626381-4	2016	Elevation of the extracellular potassium concentration ([K+]e) impairs T cell receptor (TCR)-driven Akt-mTOR phosphorylation and effector programmes.	Potassium	31-40	mechanistic target of rapamycin kinase	Mus musculus	104-108
27626381-5	2016	Potassium-mediated suppression of Akt-mTOR signalling and T cell function is dependent upon the activity of the serine/threonine phosphatase PP2A.	Potassium	0-9	thymoma viral proto-oncogene 1	Mus musculus	34-37
27626381-5	2016	Potassium-mediated suppression of Akt-mTOR signalling and T cell function is dependent upon the activity of the serine/threonine phosphatase PP2A.	Potassium	0-9	mechanistic target of rapamycin kinase	Mus musculus	38-42
27626381-5	2016	Potassium-mediated suppression of Akt-mTOR signalling and T cell function is dependent upon the activity of the serine/threonine phosphatase PP2A.	Potassium	0-9	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	Mus musculus	141-145
27626381-7	2016	Accordingly, augmenting potassium efflux in tumour-specific T cells by overexpressing the potassium channel Kv1.3 lowers [K+]i and improves effector functions in vitro and in vivo and enhances tumour clearance and survival in melanoma-bearing mice.	Potassium	24-33	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	108-113
27626070-0	2016	Structural basis for KCNE3 modulation of potassium recycling in epithelia.	Potassium	41-50	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	21-26
27422117-4	2016	Further, p53 strongly favors G-quadruplexes folded in potassium over those formed in sodium, thus indicating the telomeric G-quadruplex conformational selectivity of p53.	Potassium	54-63	tumor protein p53	Homo sapiens	9-12
27422117-4	2016	Further, p53 strongly favors G-quadruplexes folded in potassium over those formed in sodium, thus indicating the telomeric G-quadruplex conformational selectivity of p53.	Potassium	54-63	tumor protein p53	Homo sapiens	166-169
27011258-0	2016	Genetic variants in adiponectin and blood pressure responses to dietary sodium or potassium interventions: a family-based association study.	Potassium	82-91	adiponectin, C1Q and collagen domain containing	Homo sapiens	20-31
27068441-0	2016	SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.	Potassium	38-47	serine/threonine kinase 39	Mus musculus	0-4
27068441-0	2016	SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.	Potassium	38-47	odd-skipped related transcription factor 1	Mus musculus	9-13
27068441-6	2016	Potassium restriction revealed that SPAK and OSR1 play essential roles in the emerging model that NCC activation is central to sensing changes in plasma [K(+) ].	Potassium	0-9	serine/threonine kinase 39	Mus musculus	36-40
27068441-6	2016	Potassium restriction revealed that SPAK and OSR1 play essential roles in the emerging model that NCC activation is central to sensing changes in plasma [K(+) ].	Potassium	0-9	odd-skipped related transcription factor 1	Mus musculus	45-49
27068441-6	2016	Potassium restriction revealed that SPAK and OSR1 play essential roles in the emerging model that NCC activation is central to sensing changes in plasma [K(+) ].	Potassium	0-9	solute carrier family 12, member 3	Mus musculus	98-101
27068441-15	2016	SPAK-KO and kidney-specific OSR1 single knockout mice maintained plasma [K(+) ] following dietary potassium restriction, but DKO mice developed severe hypokalaemia.	Potassium	98-107	odd-skipped related transcription factor 1	Mus musculus	28-32
27521112-0	2016	Gastrointestinal potassium binding-more than just lowering serum [K(+)]: patiromer, potassium balance, and the renin angiotensin aldosterone axis.	Potassium	17-26	renin	Homo sapiens	111-116
27206969-7	2016	Interestingly, genetic inactivation of beta3-AR in mice was associated with significantly increased urine excretion of water, sodium, potassium, and chloride.	Potassium	134-143	adrenergic receptor, beta 3	Mus musculus	39-47
27011258-2	2016	The aim of this study was to assess the association of common genetic variants of the adiponectin gene with BP responses to controlled dietary sodium or potassium interventions.	Potassium	153-162	adiponectin, C1Q and collagen domain containing	Homo sapiens	86-97
27011258-10	2016	Our study indicated that the genetic polymorphisms in the adiponectin gene are significantly associated with BP responses to dietary sodium and potassium intake.	Potassium	144-153	adiponectin, C1Q and collagen domain containing	Homo sapiens	58-69
27421477-3	2016	We show that ethanol can specifically inhibit activation of the NLRP3 inflammasome, resulting in attenuated IL-1beta and caspase-1 cleavage and secretion, as well as diminished apoptosis-associated speck-like protein containing a CARD (ASC) speck formation, without affecting potassium efflux, in a mouse macrophage cell line (J774), mouse bone marrow-derived dendritic cells, mouse neutrophils, and human PBMCs.	Potassium	276-285	NLR family, pyrin domain containing 3	Mus musculus	64-69
26891693-8	2016	The formation of NLRP3/ASC/caspase-8 specks in response to TNFalpha/CHX was downstream of TNFR signaling and dependent on potassium efflux.	Potassium	122-131	tumor necrosis factor receptor superfamily, member 1a	Mus musculus	90-94
27307045-3	2016	We previously showed that neuritin up-regulates transient potassium outward current (IA) subunit Kv4.2 expression and increases IA densities, in part by activating the insulin receptor signaling pathway.	Potassium	58-67	neuritin 1	Mus musculus	26-34
27307045-3	2016	We previously showed that neuritin up-regulates transient potassium outward current (IA) subunit Kv4.2 expression and increases IA densities, in part by activating the insulin receptor signaling pathway.	Potassium	58-67	potassium voltage-gated channel, Shal-related family, member 2	Mus musculus	97-102
27276652-3	2016	In this study, we investigated the possible influence that Nogo-A may exert on other polarized molecules in Muller cells, in particular inwardly rectifying potassium channel 4.1 (Kir4.1) and aquaporin 4 (AQP4) that respectively control potassium and water exchange in glial cells.	Potassium	156-165	reticulon 4	Rattus norvegicus	59-65
27156838-2	2016	In this study, we identified a novel functional role of the 5-HT1D receptor subtype in regulating A-type potassium (K(+)) currents (IA) as well as membrane excitability in small trigeminal ganglion (TG) neurons.	Potassium	105-114	5-hydroxytryptamine (serotonin) receptor 1D	Mus musculus	60-66
27439875-3	2016	In mice lacking CRBN, CD4(+) T cells show increased activation and IL-2 production on T-cell receptor stimulation, ultimately resulting in increased potassium flux and calcium-mediated signaling.	Potassium	149-158	cereblon	Mus musculus	16-20
27439875-3	2016	In mice lacking CRBN, CD4(+) T cells show increased activation and IL-2 production on T-cell receptor stimulation, ultimately resulting in increased potassium flux and calcium-mediated signaling.	Potassium	149-158	CD4 antigen	Mus musculus	22-25
27439875-3	2016	In mice lacking CRBN, CD4(+) T cells show increased activation and IL-2 production on T-cell receptor stimulation, ultimately resulting in increased potassium flux and calcium-mediated signaling.	Potassium	149-158	interleukin 2	Mus musculus	67-71
27439875-6	2016	Consequently, in the absence of CRBN, the expression of Kv1.3 is derepressed, resulting in increased Kv1.3 expression, potassium flux, and CD4(+) T-cell hyperactivation.	Potassium	119-128	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	56-61
26891693-8	2016	The formation of NLRP3/ASC/caspase-8 specks in response to TNFalpha/CHX was downstream of TNFR signaling and dependent on potassium efflux.	Potassium	122-131	NLR family, pyrin domain containing 3	Mus musculus	17-22
26891693-8	2016	The formation of NLRP3/ASC/caspase-8 specks in response to TNFalpha/CHX was downstream of TNFR signaling and dependent on potassium efflux.	Potassium	122-131	PYD and CARD domain containing	Mus musculus	23-26
26891693-8	2016	The formation of NLRP3/ASC/caspase-8 specks in response to TNFalpha/CHX was downstream of TNFR signaling and dependent on potassium efflux.	Potassium	122-131	caspase 8	Mus musculus	27-36
26891693-8	2016	The formation of NLRP3/ASC/caspase-8 specks in response to TNFalpha/CHX was downstream of TNFR signaling and dependent on potassium efflux.	Potassium	122-131	tumor necrosis factor	Mus musculus	59-67
27258646-10	2016	Treatment with angiotensin II or increased extracellular potassium levels further stimulated aldosterone production in both CACNA1H(WT)- and CACNA1H(M1549V)-transfected cells.	Potassium	57-66	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	124-131
27258646-10	2016	Treatment with angiotensin II or increased extracellular potassium levels further stimulated aldosterone production in both CACNA1H(WT)- and CACNA1H(M1549V)-transfected cells.	Potassium	57-66	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	141-148
27338801-4	2016	Cecropin A induced undesired ion movement such as calcium accumulation and potassium leakage.	Potassium	75-84	cecropin CBM1	Bombyx mori	0-10
27140336-8	2016	This paper summarizes and expands upon a discussion at the Global Cardiovascular Clinical Trialists 2014 Forum and examines methodologic considerations for trials of new potassium binders for the prevention and management of hyperkalemia in patients with renin angiotensin aldosterone system inhibitor indications.	Potassium	170-179	renin	Homo sapiens	255-260
27151991-7	2016	Moreover, measurement of cation flux demonstrated greater loss of potassium or rubidium ions from HEK-293 cells expressing ABCB6 mutants than from cells expressing wild-type ABCB6.	Potassium	66-75	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	123-128
27151991-9	2016	In conclusion, ABCB6 missense mutations in red blood cells from subjects with familial pseudohyperkalemia show elevated potassium ion efflux.	Potassium	120-129	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	15-20
26712527-8	2016	Although these mice also exhibited deficient NCC activity, NCC could be stimulated by restricting dietary potassium, which also returned BP to control levels.	Potassium	106-115	solute carrier family 12, member 3	Mus musculus	59-62
27594164-2	2016	Studies have shown that high methylation in the promoter region of potassium voltage-gated chanel,shaker related subfamily,beta member 2,O-6-methylguanine-DNA methyltransferase,echinoderm microtubule associated protein like 2 ,ras homolog family member D ,homeobox B1 ,NNAT, and P16 inhibits the expression of these genes and regulates of the proliferation of pituitary adenoma.	Potassium	67-76	homeobox B1	Homo sapiens	256-267
27277658-4	2016	Stabilization of a parallel-stranded GQ RNA structure by monovalent potassium ions (K(+)) is required for high affinity binding to the LSD1-CoREST complex.	Potassium	68-77	lysine demethylase 1A	Homo sapiens	135-139
27101449-7	2016	PM2.5 from dust/soil and several crustal and transition metals, including strontium, iron, titanium, cobalt and magnesium, were significantly associated with increases in ET-1 at 1-day average; manganese and potassium were significantly associated with increases in ICAM-1 at 2-day average; and PM2.5 from industry and metal cadmium were significantly associated with decreases in VCAM-1 at 1-day average.	Potassium	208-217	endothelin 1	Homo sapiens	171-175
27594164-2	2016	Studies have shown that high methylation in the promoter region of potassium voltage-gated chanel,shaker related subfamily,beta member 2,O-6-methylguanine-DNA methyltransferase,echinoderm microtubule associated protein like 2 ,ras homolog family member D ,homeobox B1 ,NNAT, and P16 inhibits the expression of these genes and regulates of the proliferation of pituitary adenoma.	Potassium	67-76	neuronatin	Homo sapiens	269-273
27594164-2	2016	Studies have shown that high methylation in the promoter region of potassium voltage-gated chanel,shaker related subfamily,beta member 2,O-6-methylguanine-DNA methyltransferase,echinoderm microtubule associated protein like 2 ,ras homolog family member D ,homeobox B1 ,NNAT, and P16 inhibits the expression of these genes and regulates of the proliferation of pituitary adenoma.	Potassium	67-76	cyclin dependent kinase inhibitor 2A	Homo sapiens	279-282
27355970-2	2016	In contrast to this straightforward deprotonation of the amidine units, the reaction of 1 with the bis(trimethylsilyl)amides of sodium or potassium unexpectedly leads to a beta-metalation and an immediate deamidation reaction yielding [(thf)2 Na{Dipp-N=C(tBu)-N(H)}] (4 a) or [(thf)2 K{Dipp-N=C(tBu)-N(H)}] (4 b), respectively, as well as 2-vinylpyridine in both cases.	Potassium	138-147	nudix hydrolase 3	Homo sapiens	246-250
27355970-2	2016	In contrast to this straightforward deprotonation of the amidine units, the reaction of 1 with the bis(trimethylsilyl)amides of sodium or potassium unexpectedly leads to a beta-metalation and an immediate deamidation reaction yielding [(thf)2 Na{Dipp-N=C(tBu)-N(H)}] (4 a) or [(thf)2 K{Dipp-N=C(tBu)-N(H)}] (4 b), respectively, as well as 2-vinylpyridine in both cases.	Potassium	138-147	nudix hydrolase 3	Homo sapiens	286-290
27354609-2	2016	PATIENTS AND METHODS: We reviewed our prospectively collected dataset of patients with HIV with biopsy-proven KS; 17 out of 1,489 seropositive patients were identified with subsequent evidence of MSK involvement by KS.	Potassium	215-217	salt inducible kinase 1	Homo sapiens	196-199
27354609-7	2016	Five-year overall survival rate from initial KS diagnosis was 76%, and 60% from MSK-KS diagnosis.	Potassium	84-86	salt inducible kinase 1	Homo sapiens	80-83
27354609-5	2016	At the time of MSK-KS diagnosis, more than 80% of 14 patients had excellent HIV control.	Potassium	19-21	salt inducible kinase 1	Homo sapiens	15-18
27354609-8	2016	The majority of patients were asymptomatic and MSK-KS involvement was demonstrated during imaging prompted by progression of their mucocutaneous KS.	Potassium	51-53	salt inducible kinase 1	Homo sapiens	47-50
27354609-8	2016	The majority of patients were asymptomatic and MSK-KS involvement was demonstrated during imaging prompted by progression of their mucocutaneous KS.	Potassium	145-147	salt inducible kinase 1	Homo sapiens	47-50
27191611-2	2016	They are especially involved in potassium (K+) and water homeostasis, via inwardly rectifying K+ (Kir 4.1) and aquaporin-4 (AQP4) channels respectively.	Potassium	32-41	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	98-105
27191611-2	2016	They are especially involved in potassium (K+) and water homeostasis, via inwardly rectifying K+ (Kir 4.1) and aquaporin-4 (AQP4) channels respectively.	Potassium	32-41	aquaporin 4	Rattus norvegicus	111-122
27191611-2	2016	They are especially involved in potassium (K+) and water homeostasis, via inwardly rectifying K+ (Kir 4.1) and aquaporin-4 (AQP4) channels respectively.	Potassium	32-41	aquaporin 4	Rattus norvegicus	124-128
27062641-10	2016	l-Lactate-induced TREK1 upregulation is a novel finding of physiological significance as TREK1 channels contribute to neuroprotection by enhancing potassium buffering and glutamate clearance capacity of astrocytes.	Potassium	147-156	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	18-23
27062641-10	2016	l-Lactate-induced TREK1 upregulation is a novel finding of physiological significance as TREK1 channels contribute to neuroprotection by enhancing potassium buffering and glutamate clearance capacity of astrocytes.	Potassium	147-156	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	89-94
27189364-0	2016	Three Candida albicans potassium uptake systems differ in their ability to provide Saccharomyces cerevisiae trk1trk2 mutants with necessary potassium.	Potassium	23-32	Trk1p	Saccharomyces cerevisiae S288C	108-116
26959386-0	2016	Trichomonas vaginalis induces IL-1beta production in a human prostate epithelial cell line by activating the NLRP3 inflammasome via reactive oxygen species and potassium ion efflux.	Potassium	160-169	interleukin 1 beta	Homo sapiens	30-38
26959386-0	2016	Trichomonas vaginalis induces IL-1beta production in a human prostate epithelial cell line by activating the NLRP3 inflammasome via reactive oxygen species and potassium ion efflux.	Potassium	160-169	NLR family pyrin domain containing 3	Homo sapiens	109-114
26959386-12	2016	The NADPH oxidase inhibitor DPI and high extracellular potassium ion suppressed the production of IL-1beta, caspase-1, and the expression of NLRP3 and ASC proteins.	Potassium	55-64	interleukin 1 beta	Homo sapiens	98-106
26959386-12	2016	The NADPH oxidase inhibitor DPI and high extracellular potassium ion suppressed the production of IL-1beta, caspase-1, and the expression of NLRP3 and ASC proteins.	Potassium	55-64	caspase 1	Homo sapiens	108-117
26959386-12	2016	The NADPH oxidase inhibitor DPI and high extracellular potassium ion suppressed the production of IL-1beta, caspase-1, and the expression of NLRP3 and ASC proteins.	Potassium	55-64	NLR family pyrin domain containing 3	Homo sapiens	141-146
26959386-14	2016	CONCLUSIONS: T. vaginalis induces the formation of the NLRP3 inflammasome in human prostate epithelial cells via ROS and potassium ion efflux, and this results in IL-1beta production.	Potassium	121-130	NLR family pyrin domain containing 3	Homo sapiens	55-60
27196695-1	2016	In a potassium solution, a modified 22-meric DNA sequence Pu22-T12T13 from a region proximal to the transcription initiation site of the human VEGF gene adopts a single parallel-stranded G-quadruplex conformation with a 1:4:1 loop-size arrangement.	Potassium	5-14	vascular endothelial growth factor A	Homo sapiens	143-147
27125647-0	2016	Identification and Localization of Gold Nanoparticles in Potassium Ion Pores: Implications for Kir Blockade.	Potassium	57-66	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	95-98
27105154-4	2016	Since potassium is a well-established marker for postmortem interval (PMI) and easily can be analyzed along with sodium and chloride, we have correlated sodium and chloride levels with the potassium levels and present postmortem reference ranges relative the potassium levels.	Potassium	6-15	transmembrane protein 11	Homo sapiens	49-74
27087421-6	2016	The results revealed that vitamin C, potassium, and calcium losses in sweat were positively correlated with systolic (SBP) and diastolic (DBP) blood pressure (all P&lt;0.05).	Potassium	37-46	selenium binding protein 1	Homo sapiens	118-121
27087421-6	2016	The results revealed that vitamin C, potassium, and calcium losses in sweat were positively correlated with systolic (SBP) and diastolic (DBP) blood pressure (all P&lt;0.05).	Potassium	37-46	D-box binding PAR bZIP transcription factor	Homo sapiens	138-141
27087421-7	2016	A linear stepwise regression analysis revealed that potassium, and calcium losses in sweat adversely affected SBP and DBP (all P&lt;0.05).	Potassium	52-61	selenium binding protein 1	Homo sapiens	110-113
27087421-7	2016	A linear stepwise regression analysis revealed that potassium, and calcium losses in sweat adversely affected SBP and DBP (all P&lt;0.05).	Potassium	52-61	D-box binding PAR bZIP transcription factor	Homo sapiens	118-121
27087421-8	2016	An analysis of covariance showed that SBP increased when potassium or calcium losses in sweat were &gt;900 mg, or &gt;100 mg, respectively.	Potassium	57-66	selenium binding protein 1	Homo sapiens	38-41
27087421-9	2016	Further, DBP increased when potassium or calcium losses in sweat were &gt;600 mg or &gt;130 mg, respectively.	Potassium	28-37	D-box binding PAR bZIP transcription factor	Homo sapiens	9-12
26726755-4	2016	We describe their various functional (allosteric) states and how they are affected by substrates and allosteric effectors that include ATP, ADP, nonfolded protein substrates, potassium ions, and GroES (in the case of GroEL).	Potassium	175-184	GroEL	Escherichia coli	217-222
27277795-5	2016	Coincident with the change in the intrinsic optical signal and the negative DC potential shift we recorded an increase in potassium conductance predominantly mediated by K(+) inward rectifier (Kir)2.1, which was blocked by the NMDA receptor antagonist D-AP5.	Potassium	122-131	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	193-200
27020669-0	2016	Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.	Potassium	0-9	interleukin 17A	Homo sapiens	35-41
27020669-0	2016	Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.	Potassium	0-9	mitogen-activated protein kinase 14	Homo sapiens	104-107
27020669-0	2016	Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.	Potassium	0-9	mitogen-activated protein kinase 14	Homo sapiens	108-112
27020669-0	2016	Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.	Potassium	0-9	serum/glucocorticoid regulated kinase 1	Homo sapiens	113-117
27020669-3	2016	Thus, we explored the effects and underlying molecular mechanism of high salt and potassium supplementation on IL-17A production in T lymphocytes.	Potassium	82-91	interleukin 17A	Homo sapiens	111-117
27020669-6	2016	In the participants, IL-17A levels in plasma and in peripheral blood mononuclear cells (PBMC) were significantly increased after a high-salt diet, which was dramatically reversed when potassium was supplemented.	Potassium	184-193	interleukin 17A	Homo sapiens	21-27
27189364-0	2016	Three Candida albicans potassium uptake systems differ in their ability to provide Saccharomyces cerevisiae trk1trk2 mutants with necessary potassium.	Potassium	140-149	Trk1p	Saccharomyces cerevisiae S288C	108-116
27389830-3	2016	The results show that the classical "transient" sodium current ([Formula: see text]) contributes mainly to the nodal action potential generation in the normal and abnormal cases for the temperature range of 20-39[Formula: see text]C, as the contribution of fast and slow potassium currents ([Formula: see text] and [Formula: see text]) to the total ionic current ([Formula: see text]) is negligible.	Potassium	271-280	nodal growth differentiation factor	Homo sapiens	111-116
27020669-9	2016	We conclude potassium supplementation has a blocking effect on IL-17A production in T lymphocytes induced by salt loading.	Potassium	12-21	interleukin 17A	Homo sapiens	63-69
27968757-8	2016	Corticosteroid therapy on an outpatient basis statistically significantly decreased plasma potassium levels, especially between T1 and T2 (P = .03).	Potassium	91-100	interleukin 1 receptor like 1	Homo sapiens	128-137
27086762-0	2016	Renal physiology: mTORC2 controls potassium secretion.	Potassium	34-43	CREB regulated transcription coactivator 2	Mus musculus	18-24
27437080-1	2016	ROMK, the renal outer medullary potassium channel, is involved in potassium recycling at the thick ascending loop of Henle and potassium secretion at the cortical collecting duct in the kidney nephron.	Potassium	32-41	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-4
27437080-1	2016	ROMK, the renal outer medullary potassium channel, is involved in potassium recycling at the thick ascending loop of Henle and potassium secretion at the cortical collecting duct in the kidney nephron.	Potassium	66-75	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-4
27437080-2	2016	Because of this dual site of action, selective inhibitors of ROMK are expected to represent a new class of diuretics/natriuretics with superior efficacy and reduced urinary loss of potassium compared to standard-of-care loop and thiazide diuretics.	Potassium	181-190	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	61-65
27089248-0	2016	The Arabidopsis nitrate transporter NPF7.3/NRT1.5 is involved in lateral root development under potassium deprivation.	Potassium	96-105	nitrate transporter 1.5	Arabidopsis thaliana	36-42
27330882-9	2016	The analyses of the expression of cationic amino acid transporters (CAT) suggest that the CAT-2 transporter may be implicated in the potassium/cationic amino acid interchange in liver and pancreas.	Potassium	133-142	dominant cataract 2	Mus musculus	90-95
27196604-11	2016	Moreover, DIM and TADs may be responsible for the functional plasticity of Sox9 because they are more tolerant for molecular changes (higher Ka/Ks ratio than the HMG box domain).	Potassium	144-146	SRY-box transcription factor 9	Homo sapiens	75-79
27089248-0	2016	The Arabidopsis nitrate transporter NPF7.3/NRT1.5 is involved in lateral root development under potassium deprivation.	Potassium	96-105	nitrate transporter 1.1	Arabidopsis thaliana	43-47
26883566-7	2016	Following treatment, the release of CGRP was stimulated using capsaicin or high extracellular potassium.	Potassium	94-103	calcitonin related polypeptide alpha	Homo sapiens	36-40
27043284-0	2016	mTORC2 critically regulates renal potassium handling.	Potassium	34-43	CREB regulated transcription coactivator 2	Mus musculus	0-6
26883566-9	2016	In the absence of NGF, both paclitaxel and EpoB decreased capsaicin- and potassium-stimulated release and the total peptide content, suggesting that NGF may reverse MTA-induced hyposensitivity.	Potassium	73-82	nerve growth factor	Homo sapiens	149-152
26432904-9	2016	Mice lacking FKBP12 along the nephron also maintained a normal relationship between plasma potassium levels and the abundance of phosphorylated NCC with tacrolimus treatment.	Potassium	91-100	FK506 binding protein 1a	Mus musculus	13-19
26657714-5	2016	Following KCa activation, smooth muscle hyperpolarization is evoked by electrical coupling through myoendothelial gap junctions and/or by the potassium efflux that subsequently activates smooth muscle Kir2.1 and/or Na/K-ATPase.	Potassium	142-151	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	201-207
26574023-6	2016	Cellular IL-1beta release depended on potassium efflux and the activity of proteins nucleotide-binding oligomerization domain-like receptor protein 3 and caspase-1.	Potassium	38-47	interleukin 1 beta	Homo sapiens	9-17
26963838-5	2016	In this paper, we show that deletion of the fibulin-5 gene results in a significantly diminished contractility of the thoracic aorta in response to potassium loading despite otherwise preserved characteristic active behaviors, including axial force generation and rates of contraction and relaxation.	Potassium	148-157	fibulin 5	Mus musculus	44-53
27183948-1	2016	Neonatal Bartter syndrome (NBS) is an autosomal recessive renal tubulopathy characterized by hypokalaemic, hypochloraemic metabolic alkalosis associated with increased urinary loss of sodium, potassium, calcium and chloride.	Potassium	192-201	nibrin	Homo sapiens	27-30
26930642-10	2016	Moreover, ZFHX3 shRNA cells had a larger SERCA2a activity, ultra-rapid delayed rectifier potassium currents, transient outward currents and acetylcholine-sensitive potassium currents.	Potassium	89-98	zinc finger homeobox 3	Homo sapiens	10-15
26930642-10	2016	Moreover, ZFHX3 shRNA cells had a larger SERCA2a activity, ultra-rapid delayed rectifier potassium currents, transient outward currents and acetylcholine-sensitive potassium currents.	Potassium	164-173	zinc finger homeobox 3	Homo sapiens	10-15
26997130-1	2016	Reducing hexaazatrinaphthylene (HAN) with potassium in the presence of 18-c-6 produces [{K(18-c-6)}HAN], which contains the S=1/2 radical [HAN](.-) .	Potassium	42-51	complement C6	Homo sapiens	74-77
26966178-0	2016	Potassium and the K+/H+ Exchanger Kha1p Promote Binding of Copper to ApoFet3p Multi-copper Ferroxidase.	Potassium	0-9	ferroxidase	Saccharomyces cerevisiae S288C	91-102
26997130-1	2016	Reducing hexaazatrinaphthylene (HAN) with potassium in the presence of 18-c-6 produces [{K(18-c-6)}HAN], which contains the S=1/2 radical [HAN](.-) .	Potassium	42-51	complement C6	Homo sapiens	94-97
27007844-6	2016	Ptchd1 deletion attenuates TRN activity through mechanisms involving small conductance calcium-dependent potassium currents (SK).	Potassium	105-114	patched domain containing 1	Mus musculus	0-6
26970308-0	2016	The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux.	Potassium	112-121	spleen associated tyrosine kinase	Homo sapiens	13-16
26970308-7	2016	Using a novel live cell potassium sensor we show that Syk inhibition with OXSI-2 has no effect on potassium efflux kinetics and that blockade of potassium efflux with extracellular potassium alters Syk phosphorylation.	Potassium	24-33	spleen associated tyrosine kinase	Homo sapiens	54-57
27058598-0	2016	Potassium Uptake Mediated by Trk1 Is Crucial for Candida glabrata Growth and Fitness.	Potassium	0-9	Trk1p	Saccharomyces cerevisiae S288C	29-33
27058598-2	2016	Three types of plasma-membrane systems mediating potassium influx with different transport mechanisms have been described in yeasts: the Trk1 uniporter, the Hak cation-proton symporter and the Acu ATPase.	Potassium	49-58	Trk1p	Saccharomyces cerevisiae S288C	137-141
27058598-3	2016	The C. glabrata genome contains only one gene encoding putative system for potassium uptake, the Trk1 uniporter.	Potassium	75-84	Trk1p	Saccharomyces cerevisiae S288C	97-101
26778160-4	2016	It has been demonstrated that G-quadruplex based on PS2.M sequence under these conditions formed parallel topology, which exhibited lower activity than that observed in standard potassium-containing solution.	Potassium	178-187	taste 2 receptor member 64 pseudogene	Homo sapiens	52-55
26851241-5	2016	t-CA is a type I ligand for CYP2A6 (KS = 14.9 microM).	Potassium	36-38	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	28-34
26740507-9	2016	Notably, all mutations in KCNT1 described to date are missense mutations, and electrophysiological studies have shown that they result in increased potassium current.	Potassium	148-157	potassium sodium-activated channel subfamily T member 1	Homo sapiens	26-31
26969743-0	2016	Overexpression of the rice AKT1 potassium channel affects potassium nutrition and rice drought tolerance.	Potassium	32-41	K+ transporter 1	Arabidopsis thaliana	27-31
30675414-7	2016	Awareness of this updated integrative control mechanism for potassium homeostasis is more relevant today when the medical community is increasingly focused on leveraging and expanding established renin-angiotensin-aldosterone system inhibitor treatment regimens and on successfully coping with the challenges of managing hyperkalemia provoked by renin-angiotensin-aldosterone system inhibitors.	Potassium	60-69	renin	Homo sapiens	196-201
30675414-7	2016	Awareness of this updated integrative control mechanism for potassium homeostasis is more relevant today when the medical community is increasingly focused on leveraging and expanding established renin-angiotensin-aldosterone system inhibitor treatment regimens and on successfully coping with the challenges of managing hyperkalemia provoked by renin-angiotensin-aldosterone system inhibitors.	Potassium	60-69	renin	Homo sapiens	346-351
26829980-0	2016	AtKC1 and CIPK23 Synergistically Modulate AKT1-Mediated Low-Potassium Stress Responses in Arabidopsis.	Potassium	60-69	potassium channel protein	Arabidopsis thaliana	0-5
26631167-5	2016	At membrane potentials more positive than equilibrium potential, intracellular polyamines plug the cytosolic surface of the Kir2.1 so that potassium ions cannot pass through the pore.	Potassium	139-148	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	124-130
26944358-2	2016	The influence of intracellular angiotensin II on the regulation of potassium current and membrane potential of smooth muscle cells of mesenteric arteries and its relevance for the regulation of vascular tone was reviewed.	Potassium	67-76	angiotensinogen	Homo sapiens	31-45
26944358-4	2016	Emphasis was given to the opposite effects of intracellular and extracellular angiotensin II (Ang II) on the regulation of potassium current, membrane potential and contractility of vascular resistance vessels and its implication to vascular physiology and pathology and the possible role of epigenetic factors on the expression of angiotensin II (Ang II) and renin in vascular resistance vessels as well as its possible pathophysiological role in hypertension and other cardiovascular diseases.	Potassium	123-132	angiotensinogen	Homo sapiens	78-92
26944358-4	2016	Emphasis was given to the opposite effects of intracellular and extracellular angiotensin II (Ang II) on the regulation of potassium current, membrane potential and contractility of vascular resistance vessels and its implication to vascular physiology and pathology and the possible role of epigenetic factors on the expression of angiotensin II (Ang II) and renin in vascular resistance vessels as well as its possible pathophysiological role in hypertension and other cardiovascular diseases.	Potassium	123-132	angiotensinogen	Homo sapiens	94-100
26829980-0	2016	AtKC1 and CIPK23 Synergistically Modulate AKT1-Mediated Low-Potassium Stress Responses in Arabidopsis.	Potassium	60-69	CBL-interacting protein kinase 23	Arabidopsis thaliana	10-16
26829980-0	2016	AtKC1 and CIPK23 Synergistically Modulate AKT1-Mediated Low-Potassium Stress Responses in Arabidopsis.	Potassium	60-69	K+ transporter 1	Arabidopsis thaliana	42-46
27065867-14	2016	These findings demonstrated that activation of alpha7nAChR could decrease on-site mortality in crush syndrome, at least in part based on the decline of serum potassium through insulin signaling-Na/K-ATPase pathway.	Potassium	158-167	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	47-58
27032980-1	2016	The serotonin transporter (SERT) is an integral membrane protein that exploits preexisting sodium-, chloride-, and potassium ion gradients to catalyze the thermodynamically unfavorable movement of synaptic serotonin into the presynaptic neuron.	Potassium	115-124	Serotonin transporter	Drosophila melanogaster	4-25
27032980-1	2016	The serotonin transporter (SERT) is an integral membrane protein that exploits preexisting sodium-, chloride-, and potassium ion gradients to catalyze the thermodynamically unfavorable movement of synaptic serotonin into the presynaptic neuron.	Potassium	115-124	Serotonin transporter	Drosophila melanogaster	27-31
27034094-1	2016	Phosphohistidine phosphatase 1 (PHPT1), the only known phosphohistidine phosphatase in mammals, regulates phosphohistidine levels of several proteins including those involved in signaling, lipid metabolism, and potassium ion transport.	Potassium	211-220	phosphohistidine phosphatase 1	Homo sapiens	0-30
27034094-1	2016	Phosphohistidine phosphatase 1 (PHPT1), the only known phosphohistidine phosphatase in mammals, regulates phosphohistidine levels of several proteins including those involved in signaling, lipid metabolism, and potassium ion transport.	Potassium	211-220	phosphohistidine phosphatase 1	Homo sapiens	32-37
26732494-0	2016	Arabidopsis NRT1.5 Mediates the Suppression of Nitrate Starvation-Induced Leaf Senescence by Modulating Foliar Potassium Level.	Potassium	111-120	nitrate transporter 1.1	Arabidopsis thaliana	12-16
26928907-5	2016	The transition metal Ag has larger spontaneous polarization displacements than Pb, but the Pb-O covalence seems to be weakened compared to the potassium counterpart Pb2KNb5O15 (PKN), which may account for the similar Curie temperature and uniaxial NTE behavior for PAN and PKN.	Potassium	143-152	protein kinase N1	Homo sapiens	177-180
26923070-5	2016	Second, using high concentrations of potassium we found that HSPA1A embeds within the lipid bilayer of all phosphoinositides tested.	Potassium	37-46	heat shock protein family A (Hsp70) member 1A	Homo sapiens	61-67
26961238-5	2016	In addition, whole patch clamp analyses of single atrial myocytes revealed that the ACh-regulated potassium current (IKA ch) was significant increased in the time course of activation and deactivation (P&lt;0.01) in Rgs5 KO, compared to those in WT, mice.	Potassium	98-107	regulator of G-protein signaling 5	Mus musculus	216-220
26732494-6	2016	Moreover, when exposed to nitrate starvation, foliar potassium level decreased in nrt1.5, but adding potassium could essentially restore the early leaf senescence phenotype of nrt1.5 plants.	Potassium	53-62	nitrate transporter 1.1	Arabidopsis thaliana	82-86
26843409-2	2016	The impact of sodium, potassium, choline, guanidinium, and 1-ethyl-3-methylimidazolium chloride on the fibrillation kinetics of insulin in an acid-denaturing solvent environment is studied by fluorescence spectroscopy using thioflavin T as a fibril-specific stain.	Potassium	22-31	insulin	Homo sapiens	128-135
26937967-8	2016	In comparison with the classical model, the action potential shapes for power-law behaving potassium conductance (n gate) showed a longer peak and shallow hyperpolarization; for power-law activation of the sodium conductance (m gate), the action potentials had a sharp rise time; and for power-law inactivation of the sodium conductance (h gate) the spikes had wider peak that for low values of eta replicated pituitary- and cardiac-type action potentials.	Potassium	91-100	endothelin receptor type A	Homo sapiens	395-398
26732494-6	2016	Moreover, when exposed to nitrate starvation, foliar potassium level decreased in nrt1.5, but adding potassium could essentially restore the early leaf senescence phenotype of nrt1.5 plants.	Potassium	101-110	nitrate transporter 1.1	Arabidopsis thaliana	176-180
26732494-7	2016	Nitrate starvation also downregulated the expression of HAK5, RAP2.11, and ANN1 in nrt1.5 roots, and appeared to alter potassium level in xylem sap from nrt1.5.	Potassium	119-128	nitrate transporter 1.1	Arabidopsis thaliana	153-157
26732494-8	2016	These data suggest that NRT1.5 likely perceives nitrate starvation-derived signals to prevent leaf senescence by facilitating foliar potassium accumulation.	Potassium	133-142	nitrate transporter 1.1	Arabidopsis thaliana	24-28
26661062-2	2016	We aimed to elucidate the poorly characterised mechanisms underlying the inhibitory effect of galanin and the potential involvement of G-protein coupled inwardly rectifying potassium, Kir 3, (GIRK) channels in glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) secretion.	Potassium	173-182	glucagon	Mus musculus	210-233
26850185-8	2016	RESULTS: PMX-DHP maintained hemodynamics and the acid-base balance and significantly (P &lt; 0.05) decreased the plasma concentrations of lactate, creatinine, potassium, IL-6, and IL-10 compared with dummy-DHP.	Potassium	159-168	dihydropyrimidinase	Rattus norvegicus	13-16
26758563-0	2016	Effect of the SGLT2 Inhibitor Dapagliflozin on Potassium Levels in Patients with Type 2 Diabetes Mellitus: A Pooled Analysis.	Potassium	47-56	solute carrier family 5 member 2	Homo sapiens	14-19
26758563-3	2016	We assessed the effects of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin on serum potassium levels in a pooled analysis of clinical trials in patients with type 2 diabetes mellitus (T2DM).	Potassium	104-113	solute carrier family 5 member 2	Homo sapiens	31-62
26758563-3	2016	We assessed the effects of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin on serum potassium levels in a pooled analysis of clinical trials in patients with type 2 diabetes mellitus (T2DM).	Potassium	104-113	solute carrier family 5 member 2	Homo sapiens	64-69
26634368-4	2016	Furthermore, accumulating epidemiological evidence from, especially, the last decade relates low dietary potassium intake or serum potassium levels to an increased risk for insulin resistance or diabetes.	Potassium	105-114	insulin	Homo sapiens	173-180
26634368-4	2016	Furthermore, accumulating epidemiological evidence from, especially, the last decade relates low dietary potassium intake or serum potassium levels to an increased risk for insulin resistance or diabetes.	Potassium	131-140	insulin	Homo sapiens	173-180
26782144-0	2016	Chronic kidney disease: Potassium efflux in APOL1 nephropathy.	Potassium	24-33	apolipoprotein L1	Homo sapiens	44-49
26986142-10	2016	Among the 3 normal skin groups, the expression level of CKLF-1 was significantly higher in the KS group than in the CS or S group.	Potassium	95-97	chemokine like factor	Homo sapiens	56-62
25586061-2	2016	Furthermore, GLAST and GLT-1 are sodium-dependent Glu transporters (GluTs) that rely on sodium and potassium gradients generated principally by Na(+), K(+)-ATPase to generate ion gradients that drive Glu uptake.	Potassium	99-108	solute carrier family 1 member 3	Homo sapiens	13-18
25586061-2	2016	Furthermore, GLAST and GLT-1 are sodium-dependent Glu transporters (GluTs) that rely on sodium and potassium gradients generated principally by Na(+), K(+)-ATPase to generate ion gradients that drive Glu uptake.	Potassium	99-108	solute carrier family 1 member 2	Homo sapiens	23-28
25592718-3	2016	We find that the expression of one AP-1 member, c-Fos, is reduced in cerebellar granule neurons (CGNs) induced to die by low potassium (LK) treatment.	Potassium	125-134	FBJ osteosarcoma oncogene	Mus musculus	48-53
26508536-9	2016	While NO is an important signalling component in ABA-induced stomatal closure in Arabidopsis, our findings demonstrate a more complex interaction associating potassium nutrition and nitrogen metabolism in the nia1nia2 mutant that affects stomatal function.	Potassium	158-167	nitrate reductase 1	Arabidopsis thaliana	209-217
26537360-8	2016	We also found that a group of variants (predicted deleterious and non-coding), segregating with the comorbid MAEP/AEP subgroups, belong to proteins specifically involved in glutamate transport and metabolism (namely, SLC17A6, GRM8, and GLUL), as well as in potassium conductance (KCNN3).	Potassium	257-266	glutamate metabotropic receptor 8	Homo sapiens	226-230
26537360-8	2016	We also found that a group of variants (predicted deleterious and non-coding), segregating with the comorbid MAEP/AEP subgroups, belong to proteins specifically involved in glutamate transport and metabolism (namely, SLC17A6, GRM8, and GLUL), as well as in potassium conductance (KCNN3).	Potassium	257-266	glutamate-ammonia ligase	Homo sapiens	236-240
26537360-8	2016	We also found that a group of variants (predicted deleterious and non-coding), segregating with the comorbid MAEP/AEP subgroups, belong to proteins specifically involved in glutamate transport and metabolism (namely, SLC17A6, GRM8, and GLUL), as well as in potassium conductance (KCNN3).	Potassium	257-266	potassium calcium-activated channel subfamily N member 3	Homo sapiens	280-285
26823502-4	2016	Based on in vitro enzymatic assays using the Chaetomium thermophilum (Ct) orthologue, we show that Nug1 exhibits a low intrinsic GTPase activity that is stimulated by potassium ions, rendering Nug1 a cation-dependent GTPase.	Potassium	167-176	RNA-binding GTPase NUG1	Saccharomyces cerevisiae S288C	99-103
26823502-4	2016	Based on in vitro enzymatic assays using the Chaetomium thermophilum (Ct) orthologue, we show that Nug1 exhibits a low intrinsic GTPase activity that is stimulated by potassium ions, rendering Nug1 a cation-dependent GTPase.	Potassium	167-176	RNA-binding GTPase NUG1	Saccharomyces cerevisiae S288C	193-197
26755773-2	2016	Various stimuli including C-terminal cleavage, a high concentration of extracellular potassium, and voltage have been demonstrated to activate Panx1.	Potassium	85-94	pannexin 1	Homo sapiens	143-148
26814970-8	2016	NLRP3-activating stimuli promoted the NLRP3-NEK7 interaction in a process that was dependent on potassium efflux.	Potassium	96-105	NLR family pyrin domain containing 3	Homo sapiens	0-5
26814970-8	2016	NLRP3-activating stimuli promoted the NLRP3-NEK7 interaction in a process that was dependent on potassium efflux.	Potassium	96-105	NLR family pyrin domain containing 3	Homo sapiens	38-43
26814970-8	2016	NLRP3-activating stimuli promoted the NLRP3-NEK7 interaction in a process that was dependent on potassium efflux.	Potassium	96-105	NIMA related kinase 7	Homo sapiens	44-48
26814970-13	2016	These studies demonstrate that NEK7 is an essential protein that acts downstream of potassium efflux to mediate NLRP3 inflammasome assembly and activation.	Potassium	84-93	NIMA related kinase 7	Homo sapiens	31-35
26814970-13	2016	These studies demonstrate that NEK7 is an essential protein that acts downstream of potassium efflux to mediate NLRP3 inflammasome assembly and activation.	Potassium	84-93	NLR family pyrin domain containing 3	Homo sapiens	112-117
26683666-10	2016	These findings suggest that generation of reactive oxygen species and potassium efflux contribute to HIV-induced pyroptosis and NLRP3 inflammasome activation in podocytes.	Potassium	70-79	NLR family, pyrin domain containing 3	Mus musculus	128-133
26814970-0	2016	NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.	Potassium	64-73	NIMA related kinase 7	Homo sapiens	0-4
26814970-0	2016	NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.	Potassium	64-73	NLR family pyrin domain containing 3	Homo sapiens	33-38
26814970-4	2016	Potassium efflux is a common step that is essential for NLRP3 inflammasome activation induced by many stimuli.	Potassium	0-9	NLR family pyrin domain containing 3	Homo sapiens	56-61
26814970-5	2016	Despite extensive investigation, the molecular mechanism leading to NLRP3 activation in response to potassium efflux remains unknown.	Potassium	100-109	NLR family pyrin domain containing 3	Homo sapiens	68-73
26814970-6	2016	Here we report the identification of NEK7, a member of the family of mammalian NIMA-related kinases (NEK proteins), as an NLRP3-binding protein that acts downstream of potassium efflux to regulate NLRP3 oligomerization and activation.	Potassium	168-177	NIMA related kinase 7	Homo sapiens	37-41
26814970-6	2016	Here we report the identification of NEK7, a member of the family of mammalian NIMA-related kinases (NEK proteins), as an NLRP3-binding protein that acts downstream of potassium efflux to regulate NLRP3 oligomerization and activation.	Potassium	168-177	NLR family pyrin domain containing 3	Homo sapiens	122-127
26814970-6	2016	Here we report the identification of NEK7, a member of the family of mammalian NIMA-related kinases (NEK proteins), as an NLRP3-binding protein that acts downstream of potassium efflux to regulate NLRP3 oligomerization and activation.	Potassium	168-177	NLR family pyrin domain containing 3	Homo sapiens	197-202
26655748-9	2016	There was a significant positive correlation between serum PTH and salivary phosphorus (r=0.342, p=0.009), and between serum PTH and salivary potassium (r=0.306, p=0.020).	Potassium	142-151	parathyroid hormone	Homo sapiens	125-128
26553126-0	2016	Effects of salt intake and potassium supplementation on renalase expression in the kidneys of Dahl salt-sensitive rats.	Potassium	27-36	renalase, FAD-dependent amine oxidase	Rattus norvegicus	56-64
26553126-4	2016	In this study, we aim to investigate how salt intake and potassium supplementation affect the level of renalase in rats.	Potassium	57-66	renalase, FAD-dependent amine oxidase	Rattus norvegicus	103-111
26553126-9	2016	We also found increased mRNA level and protein level of renalase, decreased catecholamine levels in plasma, and decreased BP in SS rats treated with high salt/potassium, compared with that of the high salt SS group.	Potassium	159-168	renalase, FAD-dependent amine oxidase	Rattus norvegicus	56-64
26553126-10	2016	Taken together, the salt-induced increase and potassium-induced decrease in BP could be mediated through renalase.	Potassium	46-55	renalase, FAD-dependent amine oxidase	Rattus norvegicus	105-113
26739597-3	2016	MtK(+) ATR-channel activity was assessed polarographically from the rate of State 4 respiration and by potentiometric monitoring of potassium efflux from deenergized mitochondria.	Potassium	132-141	ATR serine/threonine kinase	Rattus norvegicus	7-10
26684962-2	2016	In this work, eight highly active sodium and potassium phenolates as highly isoselective catalysts for the ROP of rac-lactide are reported.	Potassium	45-54	AKT serine/threonine kinase 1	Homo sapiens	114-117
25430801-3	2016	Insulin therapy was delayed for 9 h to allow replenishment of potassium to safe serum levels.	Potassium	62-71	insulin	Homo sapiens	0-7
26689773-10	2016	Prolongation of ventricular APD and QT interval is related to the inhibition of multiple repolarization potassium currents, especially hERG channels.	Potassium	104-113	ETS transcription factor ERG	Homo sapiens	135-139
26699492-0	2016	APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.	Potassium	76-85	apolipoprotein L1	Homo sapiens	0-5
26699492-7	2016	These manifestations of cytotoxicity were preceded by G1 or G2 APOL1-induced net efflux of intracellular potassium as measured by X-ray fluorescence, resulting in the activation of stress-activated protein kinases (SAPKs), p38 MAPK, and JNK.	Potassium	105-114	apolipoprotein L1	Homo sapiens	63-68
26721275-3	2016	The fact that S. cerevisiae cells can grow in the presence of a broad range of concentrations of external potassium (10 muM-2.5 M) and sodium (up to 1.5 M) indicates the existence of robust mechanisms that have evolved to maintain intracellular concentrations of these cations within appropriate limits.	Potassium	106-115	Mum2p	Saccharomyces cerevisiae S288C	120-125
26138709-9	2016	Moreover, increased potassium, sourced from the BC, induced mitigation of Na uptake by maize and consequently, reduced the impact of salt stress as evidenced by overall declines in the antioxidant activities of APX and GR.	Potassium	20-29	APx1-Cytosolic Ascorbate Peroxidase	Zea mays	211-214
27069917-7	2016	Potassium ions induced apoptosis through regulating Bcl-2 family members and depolarized the mitochondrial membrane, especially for HepG2 cell.	Potassium	0-9	BCL2 apoptosis regulator	Homo sapiens	52-57
27069917-9	2016	By facilitating expression of channel protein HERG, potassium ions may prevent it from being shunted to procancerous pathways by inducing apoptosis.	Potassium	52-61	potassium voltage-gated channel subfamily H member 2	Homo sapiens	46-50
27069917-11	2016	Thus, our findings suggest that potassium ions could inhibit tumorigenesis through inducing apoptosis of hepatoma cells by upregulating potassium ions transport channel proteins HERG and VDAC1.	Potassium	32-41	potassium voltage-gated channel subfamily H member 2	Homo sapiens	178-182
27069917-11	2016	Thus, our findings suggest that potassium ions could inhibit tumorigenesis through inducing apoptosis of hepatoma cells by upregulating potassium ions transport channel proteins HERG and VDAC1.	Potassium	32-41	voltage dependent anion channel 1	Homo sapiens	187-192
26138709-9	2016	Moreover, increased potassium, sourced from the BC, induced mitigation of Na uptake by maize and consequently, reduced the impact of salt stress as evidenced by overall declines in the antioxidant activities of APX and GR.	Potassium	20-29	glutathione reductase 1	Zea mays	219-221
27455575-2	2016	Preliminary inhibition of renin-angiotensin system (RAS) activity using ACE inhibitor enalapril (1 mg/kg, orally, 7 days) increases the sensitivity of rat kidney to drug, increasing its diuretic effect 2.33 times, natriuresis 2.49 times, and urine potassium excretion 1.80 times (p &lt; 0.05).	Potassium	248-257	renin	Rattus norvegicus	26-31
26515654-2	2016	CS is caused by mutations in the SLC9A6 gene, which encodes a multipass transmembrane sodium (potassium)-hydrogen exchanger 6 (NHE6) protein, functional in early recycling endosomes.	Potassium	94-103	solute carrier family 9 (sodium/hydrogen exchanger), member 6	Mus musculus	33-39
26515654-2	2016	CS is caused by mutations in the SLC9A6 gene, which encodes a multipass transmembrane sodium (potassium)-hydrogen exchanger 6 (NHE6) protein, functional in early recycling endosomes.	Potassium	94-103	solute carrier family 9 (sodium/hydrogen exchanger), member 6	Mus musculus	127-131
27455575-4	2016	Preliminary administration of direct renin inhibitor aliskiren (4 mg/kg, orally, 7 days) is accompanied by 2.30-fold increase in the diuretic effect of propranolol, 2.56-fold increase in natriuresis, and 2.27-fold increase in urine potassium excretion (p &lt; 0.05).	Potassium	232-241	renin	Rattus norvegicus	37-42
26342809-6	2016	We first used high concentrations of potassium and established that HspA1A embeds in membranes when bound to all anionic lipids tested.	Potassium	37-46	heat shock protein family A (Hsp70) member 1A	Homo sapiens	68-74
26639094-6	2016	As a powerful regulator of transport mechanisms across the cell membrane, JAK2 regulates a wide variety of potassium, calcium, sodium and chloride ion channels, multiple Na+-coupled cellular carriers including EAAT1-4, NaPi-IIa, SGLT1, BoaT1, PepT1-2, CreaT1, SMIT1, and BGT1 as well as Na(+)/K(+)-ATPase.	Potassium	107-116	Janus kinase 2	Homo sapiens	74-78
26496924-0	2016	Aquaporin 2-labeled cells differentiate to intercalated cells in response to potassium depletion.	Potassium	77-86	aquaporin 2	Mus musculus	0-11
27419902-0	2016	Letter: Electron-capture dissociation and collision-induced dissociation fragmentation of the supermetallized complexes of Substance P with potassium, cesium and silver.	Potassium	140-149	tachykinin precursor 1	Homo sapiens	123-134
26515056-0	2016	Immunolocalization of hyperpolarization-activated cationic HCN1 and HCN3 channels in the rat nephron: regulation of HCN3 by potassium diets.	Potassium	124-133	hyperpolarization-activated cyclic nucleotide-gated potassium channel 3	Rattus norvegicus	116-120
26422504-0	2016	Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.	Potassium	81-90	WNK lysine deficient protein kinase 4	Homo sapiens	38-42
26553871-5	2016	Although it has been shown that known Nlrp3 stimuli converge on potassium ion efflux upstream of Nlrp3 activation, the exact molecular mechanism of Nlrp3 activation remains elusive.	Potassium	64-73	NLR family, pyrin domain containing 3	Mus musculus	38-43
26553871-5	2016	Although it has been shown that known Nlrp3 stimuli converge on potassium ion efflux upstream of Nlrp3 activation, the exact molecular mechanism of Nlrp3 activation remains elusive.	Potassium	64-73	NLR family, pyrin domain containing 3	Mus musculus	97-102
26553871-5	2016	Although it has been shown that known Nlrp3 stimuli converge on potassium ion efflux upstream of Nlrp3 activation, the exact molecular mechanism of Nlrp3 activation remains elusive.	Potassium	64-73	NLR family, pyrin domain containing 3	Mus musculus	97-102
26553871-7	2016	We employed a FACS-based screen for Nlrp3-dependent cell death, using the ionophoric compound nigericin as a potassium efflux-inducing stimulus.	Potassium	109-118	acyl-CoA synthetase long-chain family member 1	Mus musculus	14-18
26553871-7	2016	We employed a FACS-based screen for Nlrp3-dependent cell death, using the ionophoric compound nigericin as a potassium efflux-inducing stimulus.	Potassium	109-118	NLR family, pyrin domain containing 3	Mus musculus	36-41
27316997-4	2016	In this way, CaV1.2 activity can be measured at different membrane voltages, corresponding to either the resting or partial inactivated state, by loading the cells with a calcium probe in extracellular low or high potassium buffer.	Potassium	214-223	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	13-19
25990245-7	2016	The excess release of azurophilic granules in Hv1/VSOP-deficient neutrophils was suppressed by inhibiting NADPH oxidase activity and, in part, by valinomycin, a potassium ionophore.	Potassium	161-170	hepatitis virus (MHV-2) susceptibility	Mus musculus	46-49
26422504-5	2016	We report that modest changes in both dietary and plasma potassium affect NCC in vivo.	Potassium	57-66	solute carrier family 12 member 3	Homo sapiens	74-77
26422504-10	2016	Thus, potassium effects on NCC are graded within the physiological range, which explains how unique chloride-sensing properties of WNK4 enable it to mediate effects of potassium on NCC in vivo.	Potassium	6-15	solute carrier family 12 member 3	Homo sapiens	27-30
26422504-10	2016	Thus, potassium effects on NCC are graded within the physiological range, which explains how unique chloride-sensing properties of WNK4 enable it to mediate effects of potassium on NCC in vivo.	Potassium	6-15	WNK lysine deficient protein kinase 4	Homo sapiens	131-135
26422504-3	2016	Recent data suggest that plasma potassium affects the distal nephron directly by influencing intracellular chloride, an inhibitor of the with-no-lysine kinase (WNK)-Ste20p-related proline- and alanine-rich kinase (SPAK) pathway.	Potassium	32-41	serine/threonine kinase 39	Homo sapiens	214-218
26422504-10	2016	Thus, potassium effects on NCC are graded within the physiological range, which explains how unique chloride-sensing properties of WNK4 enable it to mediate effects of potassium on NCC in vivo.	Potassium	6-15	solute carrier family 12 member 3	Homo sapiens	181-184
26422504-10	2016	Thus, potassium effects on NCC are graded within the physiological range, which explains how unique chloride-sensing properties of WNK4 enable it to mediate effects of potassium on NCC in vivo.	Potassium	168-177	solute carrier family 12 member 3	Homo sapiens	27-30
26422504-10	2016	Thus, potassium effects on NCC are graded within the physiological range, which explains how unique chloride-sensing properties of WNK4 enable it to mediate effects of potassium on NCC in vivo.	Potassium	168-177	WNK lysine deficient protein kinase 4	Homo sapiens	131-135
26422504-10	2016	Thus, potassium effects on NCC are graded within the physiological range, which explains how unique chloride-sensing properties of WNK4 enable it to mediate effects of potassium on NCC in vivo.	Potassium	168-177	solute carrier family 12 member 3	Homo sapiens	181-184
28132471-2	2016	There are eight potassium channels known to contribute to the potassium permeability of the inner mitochondrial membrane: ATP-regulated channel, calcium-regulated channels of large, intermediate and small conductance, voltage-regulated Kv1.3 and Kv7.4 channels, two-pore-domain TASK-3 channel and SLO2 channel.	Potassium	16-25	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	246-251
27212600-2	2016	Recently a new enzyme-linked immunosorbent assay (ELISA) kit of concurrently detected anti-ARS antibodies (anti-Jo-1, anti-PL-7, anti-PL-12, anti-EJ and anti-KS) have become to measure in the clinical setting.	Potassium	158-160	secreted LY6/PLAUR domain containing 1	Homo sapiens	91-94
26905224-10	2016	CONCLUSION: It is safe to use low dose mineralocorticoid receptor antagonists on patients receiving hemodialysis, at the end of each session of hemodialysis, and close monitoring of serum potassium levels and possible side effects is necessary.	Potassium	188-197	nuclear receptor subfamily 3 group C member 2	Homo sapiens	39-65
26470810-1	2015	In rat thalamic paraventricular nucleus of thalamus (PVT) neurons, activation of thyrotropin-releasing hormone (TRH) receptors enhances excitability via concurrent decrease in G protein-coupled inwardly-rectifying potassium (GIRK)-like and activation of transient receptor potential cation (TRPC)4/5-like cationic conductances.	Potassium	214-223	thyrotropin releasing hormone	Rattus norvegicus	81-110
25989112-10	2016	Ks inversely correlated with fibrinogen, PF4 and C-reactive protein.	Potassium	0-2	platelet factor 4	Homo sapiens	41-44
25989112-10	2016	Ks inversely correlated with fibrinogen, PF4 and C-reactive protein.	Potassium	0-2	C-reactive protein	Homo sapiens	49-67
26470810-1	2015	In rat thalamic paraventricular nucleus of thalamus (PVT) neurons, activation of thyrotropin-releasing hormone (TRH) receptors enhances excitability via concurrent decrease in G protein-coupled inwardly-rectifying potassium (GIRK)-like and activation of transient receptor potential cation (TRPC)4/5-like cationic conductances.	Potassium	214-223	thyrotropin releasing hormone	Rattus norvegicus	112-115
26563378-10	2015	The annual decline rate in eGFR in the fourth quartile of urinary potassium excretion (-1.3 ml/min per 1.73 m(2)/y; 95% CI, -1.5 to -1.0) was significantly slower than those in the first quartile (-2.2; 95% CI, -2.4 to -1.8).	Potassium	66-75	epidermal growth factor receptor	Homo sapiens	27-31
26674602-9	2015	AQP2 was also detected in autophagosomes in IMCD cells of potassium-deprived rats by immunogold electron microscopy.	Potassium	58-67	aquaporin 2	Rattus norvegicus	0-4
26093176-5	2015	The emergence of 2 new potassium-binding medications for acute and chronic therapy of hyperkalemia may soon allow the continued use of medications such as renin-angiotensin-aldosterone system inhibitors even in patients who are prone to hyperkalemia.	Potassium	23-32	renin	Homo sapiens	155-160
26631004-0	2015	C-Reactive protein reactions to glucose-insulin-potassium infusion and relations to infarct size in patients with acute coronary syndromes.	Potassium	48-57	C-reactive protein	Homo sapiens	0-18
26467721-5	2015	Recently, congenital OX40 deficiency, as determined by genome-wide exome sequencing, was shown to be associated with aggressive childhood KS in a patient, suggesting that disrupted OX40-OX40L interactions might be implicated in disease development.	Potassium	138-140	TNF receptor superfamily member 4	Homo sapiens	21-25
26362633-5	2015	Measurements of adrenal CYP11B2 expression and plasma aldosterone levels showed that increases in endogenous (obesity) or exogenous (infusion) leptin dose-dependently raised CYP11B2 expression and aldosterone without elevating plasma angiotensin II, potassium or corticosterone.	Potassium	250-259	leptin	Homo sapiens	143-149
26252618-13	2015	Novel somatic KCNJ5 variants likely cause adenomas by loss of potassium selectivity, similar to previously described mutations.	Potassium	62-71	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	14-19
26485467-7	2015	Levels of potassium in serum were positively correlated with adrenocorticotrophic hormone (ACTH) and growth hormone (GH) levels (all P&lt;0.05).	Potassium	10-19	proopiomelanocortin	Homo sapiens	91-95
26485467-7	2015	Levels of potassium in serum were positively correlated with adrenocorticotrophic hormone (ACTH) and growth hormone (GH) levels (all P&lt;0.05).	Potassium	10-19	growth hormone 1	Homo sapiens	101-115
26485467-7	2015	Levels of potassium in serum were positively correlated with adrenocorticotrophic hormone (ACTH) and growth hormone (GH) levels (all P&lt;0.05).	Potassium	10-19	growth hormone 1	Homo sapiens	117-119
26405262-12	2015	Less positive tubules and less positive cells per tubule were observed for MAGE-A4 and UCHL1 expression in the KS compared with the non-treated group (P &lt; 0.01).	Potassium	111-113	MAGE family member A4	Homo sapiens	75-82
26405262-12	2015	Less positive tubules and less positive cells per tubule were observed for MAGE-A4 and UCHL1 expression in the KS compared with the non-treated group (P &lt; 0.01).	Potassium	111-113	ubiquitin C-terminal hydrolase L1	Homo sapiens	87-92
26405262-13	2015	Higher nuclear UCHL1 Sertoli cell expression was observed in the KS group compared with the non-treated group (P &lt; 0.05).	Potassium	65-67	ubiquitin C-terminal hydrolase L1	Homo sapiens	15-20
26405262-14	2015	Higher interstitial expression of INHA (P &lt; 0.05), SOX9 (P &lt; 0.01) and STAR (P &lt; 0.05) was observed in KS compared with the non-treated group.	Potassium	112-114	inhibin subunit alpha	Homo sapiens	34-38
26405262-14	2015	Higher interstitial expression of INHA (P &lt; 0.05), SOX9 (P &lt; 0.01) and STAR (P &lt; 0.05) was observed in KS compared with the non-treated group.	Potassium	112-114	SRY-box transcription factor 9	Homo sapiens	54-58
26467721-5	2015	Recently, congenital OX40 deficiency, as determined by genome-wide exome sequencing, was shown to be associated with aggressive childhood KS in a patient, suggesting that disrupted OX40-OX40L interactions might be implicated in disease development.	Potassium	138-140	TNF superfamily member 4	Homo sapiens	186-191
26405262-14	2015	Higher interstitial expression of INHA (P &lt; 0.05), SOX9 (P &lt; 0.01) and STAR (P &lt; 0.05) was observed in KS compared with the non-treated group.	Potassium	112-114	steroidogenic acute regulatory protein	Homo sapiens	77-81
26472706-3	2015	The hepatitis C virus (HCV) protein NS5A prevents the apoptosis-enabling loss of intracellular potassium by inhibiting Kv2.1 function and thus blocking hepatocyte cell death.	Potassium	95-104	potassium voltage-gated channel subfamily B member 1	Homo sapiens	119-124
26445872-0	2015	Corticotropin-releasing factor increases Purkinje neuron excitability by modulating sodium, potassium, and Ih currents.	Potassium	92-101	corticotropin releasing hormone	Rattus norvegicus	0-30
25778467-0	2015	Genetic modifiers of response to glucose-insulin-potassium (GIK) infusion in acute coronary syndromes and associations with clinical outcomes in the IMMEDIATE trial.	Potassium	49-58	insulin	Homo sapiens	41-48
25778467-1	2015	Modifiers of response to glucose, insulin and potassium (GIK) infusion may affect clinical outcomes in acute coronary syndromes (ACS).	Potassium	46-55	acyl-CoA synthetase long chain family member 1	Homo sapiens	129-132
25778467-6	2015	Gene variants may modify glucose and potassium response to GIK infusion, contributing to cardiovascular outcomes in ACS.	Potassium	37-46	acyl-CoA synthetase long chain family member 1	Homo sapiens	116-119
26472706-4	2015	Critically, neurons expressing NS5A1b (from HCV genotype 1b), but not NS5A1a, can be protected from lethal injurious stimuli via a block of Kv2.1-mediated potassium currents.	Potassium	155-164	potassium voltage-gated channel subfamily B member 1	Homo sapiens	140-145
26405101-2	2015	In heart, Kv7.1 and the accessory subunit KCNE1 forms the slowly activating delayed-rectifier potassium current current, which is enhanced by protein kinase A (PKA)-mediated phosphorylation.	Potassium	94-103	potassium voltage-gated channel subfamily E member 1	Canis lupus familiaris	42-47
26540111-7	2015	Multivariate analysis adjusted for fibrinogen showed that Ks was predicted by eosinophil count, peak thrombin generation, factor VIII, and soluble CD40 ligand, whereas eosinophil count, peak thrombin generation and antiplasmin predicted t50%.	Potassium	58-60	fibrinogen beta chain	Homo sapiens	35-45
26540111-7	2015	Multivariate analysis adjusted for fibrinogen showed that Ks was predicted by eosinophil count, peak thrombin generation, factor VIII, and soluble CD40 ligand, whereas eosinophil count, peak thrombin generation and antiplasmin predicted t50%.	Potassium	58-60	coagulation factor II, thrombin	Homo sapiens	101-109
26540111-7	2015	Multivariate analysis adjusted for fibrinogen showed that Ks was predicted by eosinophil count, peak thrombin generation, factor VIII, and soluble CD40 ligand, whereas eosinophil count, peak thrombin generation and antiplasmin predicted t50%.	Potassium	58-60	CD40 molecule	Homo sapiens	147-151
25903789-5	2015	METHODS: Lacosamide was tested in vitro on sodium and L-type calcium currents from isolated human atrial myocytes and on hERG-mediated potassium currents from stably transfected HEK293 cells.	Potassium	135-144	ETS transcription factor ERG	Homo sapiens	121-125
25976823-5	2015	PCG is a dietary source of potassium and calcium, with low levels of fat and sugar.	Potassium	27-36	psoriasis susceptibility 1 candidate 2 (human)	Mus musculus	0-3
25771952-0	2015	Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene.	Potassium	25-34	gap junction protein, alpha 1	Mus musculus	104-114
26386156-3	2015	The expression of c-fos was transiently induced by treatment of cells with high potassium (high K(+)), which evoked depolarization, or forskolin, an adenylate cyclase activator.	Potassium	80-89	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	18-23
26256678-4	2015	Upon up-regulating the kinin system by a high potassium diet we observed reduction of tubulointerstitial fibrosis, decreased renal expression of alpha-smooth muscle actin (alpha-SMA) and vimentin, reduced Smad3 phosphorylation and increase of Smad7.	Potassium	46-55	actin gamma 2, smooth muscle	Rattus norvegicus	145-170
26256678-4	2015	Upon up-regulating the kinin system by a high potassium diet we observed reduction of tubulointerstitial fibrosis, decreased renal expression of alpha-smooth muscle actin (alpha-SMA) and vimentin, reduced Smad3 phosphorylation and increase of Smad7.	Potassium	46-55	actin gamma 2, smooth muscle	Rattus norvegicus	172-181
26256678-4	2015	Upon up-regulating the kinin system by a high potassium diet we observed reduction of tubulointerstitial fibrosis, decreased renal expression of alpha-smooth muscle actin (alpha-SMA) and vimentin, reduced Smad3 phosphorylation and increase of Smad7.	Potassium	46-55	vimentin	Rattus norvegicus	187-195
26256678-4	2015	Upon up-regulating the kinin system by a high potassium diet we observed reduction of tubulointerstitial fibrosis, decreased renal expression of alpha-smooth muscle actin (alpha-SMA) and vimentin, reduced Smad3 phosphorylation and increase of Smad7.	Potassium	46-55	SMAD family member 3	Rattus norvegicus	205-210
26256678-4	2015	Upon up-regulating the kinin system by a high potassium diet we observed reduction of tubulointerstitial fibrosis, decreased renal expression of alpha-smooth muscle actin (alpha-SMA) and vimentin, reduced Smad3 phosphorylation and increase of Smad7.	Potassium	46-55	SMAD family member 7	Rattus norvegicus	243-248
26512962-1	2015	P2X7 purinergic receptor engagement with extracellular ATP induces transmembrane potassium and calcium flux resulting in assembly of the NLRP3 inflammasome in LPS-primed macrophages.	Potassium	81-90	purinergic receptor P2X 7	Homo sapiens	0-4
26512962-1	2015	P2X7 purinergic receptor engagement with extracellular ATP induces transmembrane potassium and calcium flux resulting in assembly of the NLRP3 inflammasome in LPS-primed macrophages.	Potassium	81-90	NLR family pyrin domain containing 3	Homo sapiens	137-142
26512962-4	2015	Interestingly, the mitochondrial potassium pool was mobilized in a P2X7 signaling, and ATP dose-dependent manner, suggesting a role for mitochondrial sensing of cytosolic ion perturbation.	Potassium	33-42	purinergic receptor P2X 7	Homo sapiens	67-71
26512962-6	2015	Further, intracellular calcium chelation with BAPTA-AM indicated that P2X7-induced potassium depletion was independent of calcium mobilization.	Potassium	83-92	purinergic receptor P2X 7	Homo sapiens	70-74
26512962-7	2015	This evidence suggests that both potassium efflux and calcium influx are necessary for mitochondrial reactive oxygen generation upstream of NLRP3 inflammasome assembly and pyroptotic cell death.	Potassium	33-42	NLR family pyrin domain containing 3	Homo sapiens	140-145
26512962-8	2015	We propose a model wherein potassium efflux is necessary for calcium influx, resulting in mitochondrial reactive oxygen generation to trigger the NLRP3 inflammasome.	Potassium	27-36	NLR family pyrin domain containing 3	Homo sapiens	146-151
26500494-8	2015	Fluorescent ATP markers and FFN102 puncta were found to co-localize in VNUT positive neurons and upon stimulation with high potassium, ATP marker fluorescence at the cell membrane was reduced.	Potassium	124-133	solute carrier family 17, member 9	Mus musculus	71-75
26477325-1	2015	The voltage-gated Kv2.1 potassium channel encoded by KCNB1 produces the major delayed rectifier potassium current in pyramidal neurons.	Potassium	24-33	potassium voltage-gated channel subfamily B member 1	Homo sapiens	53-58
26173909-8	2015	Furthermore, we show that active caspase-11 leads to a drop of intracellular potassium levels, which is necessary to activate NLRP3.	Potassium	77-86	NLR family pyrin domain containing 3	Homo sapiens	126-131
26415804-5	2015	METHODS: A model of potassium-induced CA was performed on TLR4-mutant mice (C3H/HeJ) and wild-type mice (C3H/HeN).	Potassium	20-29	toll-like receptor 4	Mus musculus	58-62
26141787-8	2015	RESULTS: Functional studies revealed that miR-153 mimic suppresses both glucose- and potassium-induced insulin secretion (GSIS and PSIS, respectively), whereas miR-153 inhibitor enhances both GSIS and PSIS.	Potassium	85-94	microRNA 153	Mus musculus	42-49
26174085-5	2015	In addition to caspase-4, efficient IL-1beta conversion upon intracellular LPS delivery relies on potassium efflux, NLRP3, ASC, and caspase-1, indicating that although caspase-4 activation alone is sufficient to induce pyroptosis, this process depends on the NLRP3 inflammasome activation to drive IL-1beta maturation.	Potassium	98-107	interleukin 1 beta	Homo sapiens	36-44
26385038-0	2015	Facility variation and predictors of serum potassium monitoring after initiation of a mineralocorticoid receptor antagonist in patients with heart failure.	Potassium	43-52	nuclear receptor subfamily 3 group C member 2	Homo sapiens	86-112
26332156-0	2015	Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways.	Potassium	0-9	NLR family pyrin domain containing 3	Homo sapiens	102-107
26332156-0	2015	Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways.	Potassium	34-43	NLR family pyrin domain containing 3	Homo sapiens	102-107
26136181-4	2015	Most calretinin cells (85%) exhibited large A-type potassium currents and delayed firing action potential discharge, and received strong excitatory synaptic input, whereas the remainder exhibited hyperpolarization-activated cation currents and low threshold T-type calcium currents, and tonic- or initial bursting firing patterns, and received weak excitatory synaptic input.	Potassium	51-60	calbindin 2	Mus musculus	5-15
26136181-12	2015	Typical CR-expressing neurons comprised ~85% of the population and exhibited characteristic excitatory interneuron properties including delayed firing discharge, large rapid A-type potassium currents, and central, radial or vertical cell morphologies.	Potassium	181-190	calbindin 2	Mus musculus	8-10
26136181-17	2015	Under normal conditions, the contribution of "Typical" excitatory CR-expressing neurons to overall SDH excitability may be limited by the presence of A-type potassium currents, which limit the effectiveness of their strong excitatory input.	Potassium	157-166	calbindin 2	Mus musculus	66-68
26105002-6	2015	Among the potassium currents responsible for AP repolarization phase, IK1 was found to be almost insensitive to niferidil.	Potassium	10-19	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	70-73
25853863-6	2015	In addition, dexamethasone treatment of enteroendocrine GLUTag cells reduced GLP-1 secretion induced by glucose, 2-deoxy-D-glucose, fructose and potassium, whereas the secretory response to a phorbol ester was unaltered.	Potassium	145-154	glucagon	Mus musculus	77-82
26022182-0	2015	ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells.	Potassium	62-71	Eph receptor B1	Rattus norvegicus	0-3
26022182-0	2015	ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells.	Potassium	62-71	thyrotropin releasing hormone	Rattus norvegicus	30-33
26022182-0	2015	ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells.	Potassium	62-71	RAS-like, estrogen-regulated, growth-inhibitor	Rattus norvegicus	56-61
25856239-6	2015	Here we show that OECs express voltage-dependent potassium currents compatible with inward rectifier (Kir ) and delayed rectifier (KDR ) channels.	Potassium	49-58	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	102-105
25856239-6	2015	Here we show that OECs express voltage-dependent potassium currents compatible with inward rectifier (Kir ) and delayed rectifier (KDR ) channels.	Potassium	49-58	kinase insert domain receptor	Homo sapiens	131-134
26307551-2	2015	The KCNQ1/KCNE1 complex in cardiomyocytes exhibited slow activated potassium (I(ks)) currents.	Potassium	80-82	potassium voltage-gated channel subfamily KQT member 1	Cavia porcellus	4-9
25784710-7	2015	Overall, the use of mineralocorticoid receptor antagonists was associated with an increased serum potassium (0.23, 95% CI 0.13, 0.33 mmol/l; p&lt;0.0001) and higher risk ratio (1.76, 95% CI 1.20, 2.57; p=0.001) of hyperkalemia.	Potassium	98-107	nuclear receptor subfamily 3 group C member 2	Homo sapiens	20-46
26179130-0	2015	Estrogen suppresses epileptiform activity by enhancing Kv4.2-mediated transient outward potassium currents in primary hippocampal neurons.	Potassium	88-97	potassium voltage-gated channel subfamily D member 2	Homo sapiens	55-60
25827095-8	2015	Potassium-induced depolarization rapidly de-clustered dynamin 3 from nerve terminals within minutes.	Potassium	0-9	dynamin 3	Homo sapiens	54-63
26312501-2	2015	This hyperactivity is caused, at least in part, by decreased Kv7.2/3 (KCNQ2/3) potassium currents.	Potassium	79-88	potassium voltage-gated channel, subfamily Q, member 2	Mus musculus	70-75
26307551-2	2015	The KCNQ1/KCNE1 complex in cardiomyocytes exhibited slow activated potassium (I(ks)) currents.	Potassium	80-82	potassium voltage-gated channel subfamily E member 1	Cavia porcellus	10-15
26264372-12	2015	Analysis of selection pressure on protein-coding genes using Ka/Ks ratio showed significant positive selection exerted on the rps7 gene of the pineapple chloroplast with P less than 0.05.	Potassium	64-66	rps7	Ananas comosus	126-130
26304939-3	2015	The renal outer medullary kidney potassium channel subunit, potassium inward rectifying (Kir)1.1, has been implicated as a mitochondrial channel pore-forming subunit.	Potassium	33-42	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	89-96
25640031-14	2015	Moreover, long-term diuretic use was associated with SCC risk, driven by potassium-sparing agents alone or in combination with low-ceiling diuretics.	Potassium	73-82	serpin family B member 3	Homo sapiens	53-56
26272420-1	2015	Calcium-activated potassium ion channel-3.1 (KCa3.1) plays a pivotal role in the potassium-calcium exchange involved in atopy.	Potassium	18-27	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	45-51
26023797-3	2015	Marked reduction of uncoupling protein 2 (UCP2) expression upon high salt-low potassium diet associates with increased renal injury in SHRSP.	Potassium	78-87	uncoupling protein 2	Rattus norvegicus	20-40
26023797-3	2015	Marked reduction of uncoupling protein 2 (UCP2) expression upon high salt-low potassium diet associates with increased renal injury in SHRSP.	Potassium	78-87	uncoupling protein 2	Rattus norvegicus	42-46
26048399-10	2015	Multiple linear regression adjusted for age, gender, body mass index and fibrinogen showed that TG (beta=-0.41), vWF (beta=-0.29) and PF4 (beta=-0.28) are the independent predictors of Ks (R(2)=0.78), while CLT was independently predicted by TG (beta=0.37), PAI-1 antigen (beta=0.29) and vWF (beta=0.26) in the AF group (R(2)=0.39).	Potassium	185-187	platelet factor 4	Homo sapiens	134-137
26013542-3	2015	We observed that Cmpd101 inhibits the desensitization of the G protein-activated inwardly-rectifying potassium current evoked by receptor-saturating concentrations of methionine-enkephalin (Met-Enk), [d-Ala(2), N-MePhe(4), Gly-ol(5)]-enkephalin (DAMGO), endomorphin-2, and morphine in rat and mouse locus coeruleus (LC) neurons.	Potassium	101-110	proenkephalin	Rattus norvegicus	178-188
26013542-3	2015	We observed that Cmpd101 inhibits the desensitization of the G protein-activated inwardly-rectifying potassium current evoked by receptor-saturating concentrations of methionine-enkephalin (Met-Enk), [d-Ala(2), N-MePhe(4), Gly-ol(5)]-enkephalin (DAMGO), endomorphin-2, and morphine in rat and mouse locus coeruleus (LC) neurons.	Potassium	101-110	proenkephalin	Rattus norvegicus	194-197
26013542-3	2015	We observed that Cmpd101 inhibits the desensitization of the G protein-activated inwardly-rectifying potassium current evoked by receptor-saturating concentrations of methionine-enkephalin (Met-Enk), [d-Ala(2), N-MePhe(4), Gly-ol(5)]-enkephalin (DAMGO), endomorphin-2, and morphine in rat and mouse locus coeruleus (LC) neurons.	Potassium	101-110	proenkephalin	Rattus norvegicus	234-244
25814167-4	2015	KS-IMM cells expressed increased levels of inflammatory cyclooxygenase 2 (COX-2) and 5-lipoxygenase (5-LO) pathway enzymes when compared with human microvascular dermal endothelial cells (HMVEC-d).	Potassium	0-2	prostaglandin-endoperoxide synthase 2	Homo sapiens	56-72
25814167-4	2015	KS-IMM cells expressed increased levels of inflammatory cyclooxygenase 2 (COX-2) and 5-lipoxygenase (5-LO) pathway enzymes when compared with human microvascular dermal endothelial cells (HMVEC-d).	Potassium	0-2	prostaglandin-endoperoxide synthase 2	Homo sapiens	74-79
25814167-4	2015	KS-IMM cells expressed increased levels of inflammatory cyclooxygenase 2 (COX-2) and 5-lipoxygenase (5-LO) pathway enzymes when compared with human microvascular dermal endothelial cells (HMVEC-d).	Potassium	0-2	arachidonate 5-lipoxygenase	Homo sapiens	85-99
25814167-11	2015	Treatment of KS-IMM cells with LXA4 resulted in selective localization of VEGFR-2 in nonlipid raft (non-LR) and ALXR to LR fractions.	Potassium	13-15	kinase insert domain receptor	Homo sapiens	74-81
25814167-11	2015	Treatment of KS-IMM cells with LXA4 resulted in selective localization of VEGFR-2 in nonlipid raft (non-LR) and ALXR to LR fractions.	Potassium	13-15	formyl peptide receptor 2	Homo sapiens	112-116
26039623-6	2015	Potassium supplementation resulted in reduction of SBP by 4.7 mmHg [95% confidence interval (CI) 2.4-7.0] and DBP by 3.5 mmHg (95% CI 1.3-5.7) in all patients.	Potassium	0-9	selenium binding protein 1	Homo sapiens	51-54
26380428-8	2015	Labs were notable for potassium"s running on the low side of normal and low levels of both renin (less than 0.6 with normal less than or equal to 0.6-3.0) and aldosterone (1.0 with normal 3-16 ng/dL).	Potassium	22-31	renin	Homo sapiens	91-96
26048399-10	2015	Multiple linear regression adjusted for age, gender, body mass index and fibrinogen showed that TG (beta=-0.41), vWF (beta=-0.29) and PF4 (beta=-0.28) are the independent predictors of Ks (R(2)=0.78), while CLT was independently predicted by TG (beta=0.37), PAI-1 antigen (beta=0.29) and vWF (beta=0.26) in the AF group (R(2)=0.39).	Potassium	185-187	serpin family E member 1	Homo sapiens	258-263
26048399-10	2015	Multiple linear regression adjusted for age, gender, body mass index and fibrinogen showed that TG (beta=-0.41), vWF (beta=-0.29) and PF4 (beta=-0.28) are the independent predictors of Ks (R(2)=0.78), while CLT was independently predicted by TG (beta=0.37), PAI-1 antigen (beta=0.29) and vWF (beta=0.26) in the AF group (R(2)=0.39).	Potassium	185-187	von Willebrand factor	Homo sapiens	288-291
26217182-0	2015	Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis.	Potassium	96-105	solute carrier family 12 member 6	Homo sapiens	52-56
26013830-1	2015	CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle"s loop and for potassium secretion by the stria vascularis in the inner ear.	Potassium	93-102	barttin CLCNK type accessory subunit beta	Homo sapiens	6-13
26501103-9	2015	We therefore conducted whole cell patch clamp measurements of M-type potassium currents, which showed a ~ 90% decrease in Ts65Dn neurons, while HCN measurements displayed an increase of ~ 65% in Ts65Dn cells.	Potassium	69-78	reciprocal translocation, Chr 16, cytogenetic band C3-4; and Chr 17, cytogenetic band A2, Davisson 65	Mus musculus	122-128
25872187-0	2015	VEGF attenuated increase of outward delayed-rectifier potassium currents in hippocampal neurons induced by focal ischemia via PI3-K pathway.	Potassium	54-63	vascular endothelial growth factor A	Rattus norvegicus	0-4
25872187-2	2015	The present study investigated whether VEGF could attenuate ischemia-induced increase of the potassium currents in the hippocampal pyramidal neurons of rats after ischemic injury.	Potassium	93-102	vascular endothelial growth factor A	Rattus norvegicus	39-43
25863256-0	2015	Urocortin2 prolongs action potential duration and modulates potassium currents in guinea pig myocytes and HEK293 cells.	Potassium	60-69	LOW QUALITY PROTEIN: urocortin-2	Cavia porcellus	0-10
25863256-2	2015	This study goal was to further test the hypothesis that urocortin2 may modulate action potentials as well as rapidly and slowly activating delayed rectifier potassium currents.	Potassium	157-166	LOW QUALITY PROTEIN: urocortin-2	Cavia porcellus	56-66
25863256-8	2015	And urocortin2 caused reduction of rapidly activating delayed rectifier potassium currents in hERG-HEK293 cells.	Potassium	72-81	LOW QUALITY PROTEIN: urocortin-2	Cavia porcellus	4-14
25863256-9	2015	In addition, urocortin2 slowed the rate of slowly activating delayed rectifier potassium channel activation, and rightward shifted the threshold of slowly activating delayed rectifier potassium currents to more positive potentials.	Potassium	79-88	LOW QUALITY PROTEIN: urocortin-2	Cavia porcellus	13-23
26103554-7	2015	These observations indicate that the WT and the Val302del mutant subunits co-assemble in the cell membrane and that the mutation affects potassium conductivity and (or) gating of the WT/Val302del heteromeric Kir2.1 channels.	Potassium	137-146	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	208-214
26036654-11	2015	For a rapid drop in potassium by shifting the potassium to the intracellular space, administration of glucose with insulin and high-dose inhalative administration of betamimetics can be used.	Potassium	20-29	insulin	Homo sapiens	115-122
25984914-1	2015	In an atmosphere of potassium ions, a modified c-MYC NHE III1 sequence with two G-to-T mutations (MYC22-G14T/G23T) forms a highly stable parallel-stranded G-quadruplex.	Potassium	20-29	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	47-52
25127675-3	2015	We report here that Kir1.1 channels are required for gastric acid secretion and that this channel participates with Kv7.1 (KCNQ1/KvLQT1) in the potassium recycling process.	Potassium	144-153	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	20-26
25127675-3	2015	We report here that Kir1.1 channels are required for gastric acid secretion and that this channel participates with Kv7.1 (KCNQ1/KvLQT1) in the potassium recycling process.	Potassium	144-153	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	123-128
25127675-3	2015	We report here that Kir1.1 channels are required for gastric acid secretion and that this channel participates with Kv7.1 (KCNQ1/KvLQT1) in the potassium recycling process.	Potassium	144-153	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	129-135
25127675-6	2015	Luminal application of potassium-restored acid secretion in perfused gastric glands from Kir1.1-deficient as well as barium-blocked wild-type mice.	Potassium	23-32	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	89-95
26104484-1	2015	TLR2 promotes NLRP3 inflammasome activation via an early MyD88-IRAK1-dependent pathway that provides a priming signal (signal 1) necessary for activation of the inflammasome by a second potassium-depleting signal (signal 2).	Potassium	186-195	toll like receptor 2	Homo sapiens	0-4
26104484-1	2015	TLR2 promotes NLRP3 inflammasome activation via an early MyD88-IRAK1-dependent pathway that provides a priming signal (signal 1) necessary for activation of the inflammasome by a second potassium-depleting signal (signal 2).	Potassium	186-195	NLR family pyrin domain containing 3	Homo sapiens	14-19
26104484-1	2015	TLR2 promotes NLRP3 inflammasome activation via an early MyD88-IRAK1-dependent pathway that provides a priming signal (signal 1) necessary for activation of the inflammasome by a second potassium-depleting signal (signal 2).	Potassium	186-195	MYD88 innate immune signal transduction adaptor	Homo sapiens	57-62
26104484-1	2015	TLR2 promotes NLRP3 inflammasome activation via an early MyD88-IRAK1-dependent pathway that provides a priming signal (signal 1) necessary for activation of the inflammasome by a second potassium-depleting signal (signal 2).	Potassium	186-195	interleukin 1 receptor associated kinase 1	Homo sapiens	63-68
25912880-10	2015	However, amphetamine (30 microm)-induced potassium currents produced by efflux of DA were enhanced in BACE1(-/-) mice, perhaps indicating increased vesicular DA content in the midbrain.	Potassium	41-50	beta-site APP cleaving enzyme 1	Mus musculus	102-107
26057242-4	2015	Our goal is to determine if the inward rectifying potassium current (IK1) causes the inhibition of hyperpolarization.	Potassium	50-59	IKAROS family zinc finger 1	Homo sapiens	69-72
25970152-6	2015	Exhaustive reduction of the tris-[8]annulenyl isocyanurate with potassium in THF generates the first-ever observed hexa-anion of an isocyanurate.	Potassium	64-73	hexosaminidase subunit alpha	Homo sapiens	115-119
26175853-3	2015	K(+) channel interaction protein 2 (KChIP2) is a necessary subunit for the formation of transient outward potassium current (Ito.f) which plays a critical role in early repolarization and QTc interval of heart.	Potassium	106-115	Kv channel-interacting protein 2	Mus musculus	0-34
25777080-0	2015	A physiological, biochemical and proteomic characterization of Saccharomyces cerevisiae trk1,2 transport mutants grown under limiting potassium conditions.	Potassium	134-143	Trk1p	Saccharomyces cerevisiae S288C	88-92
25777080-4	2015	Using a combination of physiological, biochemical and proteomic approaches, we show that during growth at suboptimal potassium concentrations, double trk1,2 mutants accumulate less potassium and reach lower yields.	Potassium	117-126	Trk1p	Saccharomyces cerevisiae S288C	150-154
25777080-4	2015	Using a combination of physiological, biochemical and proteomic approaches, we show that during growth at suboptimal potassium concentrations, double trk1,2 mutants accumulate less potassium and reach lower yields.	Potassium	181-190	Trk1p	Saccharomyces cerevisiae S288C	150-154
25966806-0	2015	A relationship between serum potassium concentration and insulin resistance in patients with type 2 diabetes mellitus.	Potassium	29-38	insulin	Homo sapiens	57-64
25966806-2	2015	However, the relationship between serum potassium concentration and insulin resistance is poorly defined.	Potassium	40-49	insulin	Homo sapiens	68-75
25966806-3	2015	This study aimed to investigate the association between serum potassium concentration and insulin resistance in these patients.	Potassium	62-71	insulin	Homo sapiens	90-97
25966806-6	2015	The association between serum potassium concentration and insulin resistance was analyzed using linear regression methods.	Potassium	30-39	insulin	Homo sapiens	58-65
25966806-10	2015	When the patients were compared based on insulin resistance, serum potassium concentration was higher in the patients with insulin resistance compared with the patients without (4.25 +- 0.48 vs. 4.09 +- 0.44 mEq/l, p = 0.015).	Potassium	67-76	insulin	Homo sapiens	41-48
25966806-10	2015	When the patients were compared based on insulin resistance, serum potassium concentration was higher in the patients with insulin resistance compared with the patients without (4.25 +- 0.48 vs. 4.09 +- 0.44 mEq/l, p = 0.015).	Potassium	67-76	insulin	Homo sapiens	123-130
25966806-14	2015	CONCLUSIONS: Serum potassium concentration is likely to be increased in the patients with poorly controlled type 2 DM with insulin resistance than in those without insulin resistance.	Potassium	19-28	insulin	Homo sapiens	123-130
25966806-14	2015	CONCLUSIONS: Serum potassium concentration is likely to be increased in the patients with poorly controlled type 2 DM with insulin resistance than in those without insulin resistance.	Potassium	19-28	insulin	Homo sapiens	164-171
25938784-6	2015	Inward rectifying, ATP-sensitive potassium (K(ATP)) channels mediated the response to elevated glucose levels, as pharmacological manipulation of K(ATP) channels in the hippocampus altered both ISF Abeta levels and neuronal activity.	Potassium	33-42	amyloid beta (A4) precursor protein	Mus musculus	198-203
26175853-3	2015	K(+) channel interaction protein 2 (KChIP2) is a necessary subunit for the formation of transient outward potassium current (Ito.f) which plays a critical role in early repolarization and QTc interval of heart.	Potassium	106-115	Kv channel-interacting protein 2	Mus musculus	36-42
26467143-1	2015	Voltage-gated potassium channels, Kv1.3, which were discovered in 1984, are integral membrane proteins which are activated ("open") upon change of the cell membrane potential, enabling a passive flux of potassium ions across the cell membrane.	Potassium	14-23	potassium voltage-gated channel subfamily A member 3	Homo sapiens	34-39
25953924-8	2015	The shortened QTc interval from Cirp ablation was tightly linked to an abbreviated action potential duration in cardiac myocytes, which was attributable to increased transient outward potassium current (Ito).	Potassium	184-193	cold inducible RNA binding protein	Rattus norvegicus	32-36
25847511-3	2015	In the present study, we investigated the expression pattern and role of SOX7 in potassium deprivation-induced rat cerebellar granule neuron apoptosis.	Potassium	81-90	SRY-box transcription factor 7	Rattus norvegicus	73-77
25500109-15	2015	CONCLUSIONS: Important lifestyle- and diet-related factors associated with copeptin concentration are current smoking, alcohol use, protein and potassium intake, and particularly fluid and sodium intake.	Potassium	144-153	arginine vasopressin	Homo sapiens	75-83
25402014-7	2015	In line with this, we show that A2A R promotes synchronous pyramidal cell firing in hyperexcitable conditions where extracellular potassium is elevated or following high-frequency electrical stimulation.	Potassium	130-139	adenosine A2a receptor	Homo sapiens	32-37
25687974-1	2015	Potassium ion (K+) uptake in yeast is mediated mainly by the Trk1/2 proteins that enable cells to survive on external K+ concentration as low as a few muM.	Potassium	0-9	Trk1p	Saccharomyces cerevisiae S288C	61-67
25825440-7	2015	Additionally, potassium efflux and lysosomal acidification induced by the fungus were important steps in the caspase-1 activation mechanism.	Potassium	14-23	caspase 1	Mus musculus	109-118
25847511-4	2015	Our results showed that both mRNA and protein levels of SOX7 were upregulated when potassium was deprived.	Potassium	83-92	SRY-box transcription factor 7	Rattus norvegicus	56-60
25847511-6	2015	Moreover, we found that beta-catenin activity was suppressed during apoptosis and that beta-catenin inhibition was crucial for potassium deprivation-induced neuronal apoptosis.	Potassium	127-136	catenin beta 1	Rattus norvegicus	87-99
25539776-1	2015	We studied the potassium current flowing through TREK-1 channels in rat cardiac ventricular myocytes.	Potassium	15-24	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	49-55
25600998-12	2015	Taken together, these results indicate that root uptake of arsenate is probably not via sulfate transporters, but the poor growth of the double mutant of sultr1;1 and sultr1;2 was due to its poor sulfate status and decreased levels of thiols, which had pleiotropic effects on the root uptake and translocation of potassium and phosphorus and arsenic tolerance.	Potassium	313-322	sulfate transporter 1;1	Arabidopsis thaliana	154-175
25393609-6	2015	Potassium-induced depolarization demonstrates release of tau and tau fragments from pre-synaptic terminals, with increased release from AD compared to control samples.	Potassium	0-9	microtubule associated protein tau	Homo sapiens	57-60
25393609-6	2015	Potassium-induced depolarization demonstrates release of tau and tau fragments from pre-synaptic terminals, with increased release from AD compared to control samples.	Potassium	0-9	microtubule associated protein tau	Homo sapiens	65-68
25904892-2	2015	Salicylate-induced hearing loss is believed to arise from a reduction in the electromotile response of outer hair cells (OHCs) and/or reduction of KCNQ4 potassium currents in OHCs, which decreases the driving force for the transduction current.	Potassium	153-162	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	147-152
25867027-5	2015	The resting state was changed to a period-1 firing pattern via on-off firing pattern as the potassium concentration, static pressure, or depolarization current was changed.	Potassium	92-101	period circadian regulator 1	Rattus norvegicus	35-43
26336742-3	2015	5-100 LM of H2S donor--sodium hydrosulfide (NaHS) increased mechanical tension of SMC precontracted with high potassium solution that was abolished by bumetanide--the inhibitor of Na+, K+, 2Cl(-) -cotransporter (NKCC), but 100-1000 microM of NaHS relaxed SMS.	Potassium	110-119	solute carrier family 12 member 1	Homo sapiens	180-210
25805816-1	2015	With-no-lysine kinase 4 (WNK4) inhibits the activity of the potassium channel KCNJ1 (ROMK) in the distal nephron, thereby contributing to the maintenance of potassium homeostasis.	Potassium	60-69	WNK lysine deficient protein kinase 4	Homo sapiens	0-23
25805816-1	2015	With-no-lysine kinase 4 (WNK4) inhibits the activity of the potassium channel KCNJ1 (ROMK) in the distal nephron, thereby contributing to the maintenance of potassium homeostasis.	Potassium	60-69	WNK lysine deficient protein kinase 4	Homo sapiens	25-29
25805816-1	2015	With-no-lysine kinase 4 (WNK4) inhibits the activity of the potassium channel KCNJ1 (ROMK) in the distal nephron, thereby contributing to the maintenance of potassium homeostasis.	Potassium	60-69	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	78-83
25805816-1	2015	With-no-lysine kinase 4 (WNK4) inhibits the activity of the potassium channel KCNJ1 (ROMK) in the distal nephron, thereby contributing to the maintenance of potassium homeostasis.	Potassium	60-69	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	85-89
25614660-4	2015	Acute salt stress caused the strongest membrane potential depolarization, highest sodium and proton influx, and potassium loss from npr1-5 roots in comparison with the wild type and nudt7 mutant.	Potassium	112-121	regulatory protein (NPR1)	Arabidopsis thaliana	132-136
25614660-6	2015	Long-term salt exposure resulted in the highest sodium and the lowest potassium concentration in the shoots of npr1-5 mutant in comparison with the wild type and nudt7 mutant.	Potassium	70-79	regulatory protein (NPR1)	Arabidopsis thaliana	111-117
25714986-1	2015	The repair ligation-mediated light-producing DNA machine can produce light through transforming the repetitive DNA cleavage/ligation motions into optical energy without the requirement of either external reporting reagents or excitation light, and it can be applied for sensitive and selective detection of DNA, thrombin, adenosine, potassium ions (K(+)) and endonuclease even in human serum.	Potassium	333-342	coagulation factor II, thrombin	Homo sapiens	312-320
25681192-6	2015	Amylosin may thus trigger the activation of the NLRP3 inflammasome and subsequently cytokine release by causing potassium efflux from exposed cells.	Potassium	112-121	NLR family pyrin domain containing 3	Homo sapiens	48-53
25614660-7	2015	The above results demonstrate that NPR1-dependent SA signalling is pivotal to (i) controlling Na(+) entry into the root tissue and its subsequent long-distance transport into the shoot, and (ii) preventing a potassium loss through depolarization-activated outward-rectifying potassium and ROS-activated non-selective cation channels.	Potassium	208-217	regulatory protein (NPR1)	Arabidopsis thaliana	35-39
25614660-7	2015	The above results demonstrate that NPR1-dependent SA signalling is pivotal to (i) controlling Na(+) entry into the root tissue and its subsequent long-distance transport into the shoot, and (ii) preventing a potassium loss through depolarization-activated outward-rectifying potassium and ROS-activated non-selective cation channels.	Potassium	275-284	regulatory protein (NPR1)	Arabidopsis thaliana	35-39
25683504-9	2015	Careful potassium level monitoring in concomitant users of spironolactone and ACE/ARB is necessary.	Potassium	8-17	angiotensin I converting enzyme	Homo sapiens	78-81
25793825-2	2015	We observe stick-slip dynamics for thin water films confined by mica sheets, involving periodic breaking-reforming transitions of atomic-scale capillary water bridges formed around the potassium ions of mica.	Potassium	185-194	MHC class I polypeptide-related sequence A	Homo sapiens	64-68
26081057-0	2015	[Effects of activity of 11beta-hydroxysteroid dehydrogenase type 2 on serum potassium levels in Cushing"s syndrome patients].	Potassium	76-85	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	24-66
25793825-2	2015	We observe stick-slip dynamics for thin water films confined by mica sheets, involving periodic breaking-reforming transitions of atomic-scale capillary water bridges formed around the potassium ions of mica.	Potassium	185-194	MHC class I polypeptide-related sequence A	Homo sapiens	203-207
25545278-13	2015	Overall, our work emphasizes that measured intrinsic properties (inward rectification and external [K] dependence) and localization of Kir channels in the TTS membranes are ideally suited for re-capturing potassium ions from the TTS lumen during, and immediately after, repetitive stimulation under physiological conditions.	Potassium	205-214	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	135-138
25477470-3	2015	The relative abundance and role of FL- vs. KS-SPAK in regulating Na(+)-K(+)-2Cl(-) cotransporter (NKCC2) in thick ascending limb (TAL) are not completely understood.	Potassium	43-45	solute carrier family 12, member 1	Mus musculus	98-103
25477470-6	2015	The ratios of FL-SPAK to KS-SPAK in mTAL, cTAL, and DCT were 12.3, 12.5, and 10.2, respectively.	Potassium	25-27	serine/threonine kinase 39	Mus musculus	28-32
25514102-11	2015	AR CAG repeat length was comparable in KS and controls, and among KS CAG correlated to arm length (P = .04), arm span (P = .01), and leg length (P = .04).	Potassium	39-41	androgen receptor	Homo sapiens	0-2
25322916-7	2015	Our results demonstrated that out of the 21 biomarkers screened at mRNA and protein levels, alpha2beta1-integrin, Hsp27, PAI-2, MMP-19 and CGRP showed significantly higher expression (p &lt; 0.05) in KS compared to NS and HS.	Potassium	200-202	calcitonin related polypeptide alpha	Homo sapiens	139-143
25301495-6	2015	Furthermore, the cell patch-clamp test demonstrated that the overexpression of GDNF and NT-3 in BMSCs enhanced voltage-activated potassium currents, implying that BMSCs possess great potential as a cell-based therapeutic candidate to treat neurological diseases.	Potassium	129-138	glial cell derived neurotrophic factor	Rattus norvegicus	79-83
25301495-6	2015	Furthermore, the cell patch-clamp test demonstrated that the overexpression of GDNF and NT-3 in BMSCs enhanced voltage-activated potassium currents, implying that BMSCs possess great potential as a cell-based therapeutic candidate to treat neurological diseases.	Potassium	129-138	neurotrophin 3	Rattus norvegicus	88-92
24899236-3	2015	Mutations of Kir channels cause human hereditary diseases collectively called Kir channelopathies, many of which are characterized by disorders of sodium and potassium homeostasis.	Potassium	158-167	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	13-16
25712016-0	2015	Identification of a key residue in Kv7.1 potassium channel essential for sensing external potassium ions.	Potassium	41-50	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	35-40
24899236-3	2015	Mutations of Kir channels cause human hereditary diseases collectively called Kir channelopathies, many of which are characterized by disorders of sodium and potassium homeostasis.	Potassium	158-167	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	78-81
24899236-4	2015	Studies on these genetic Kir channelopathies have shed light on novel pathophysiological mechanisms, including renal sodium and potassium handling, potassium shifting in skeletal muscles, and aldosterone production in the adrenal glands.	Potassium	128-137	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	25-28
24899236-4	2015	Studies on these genetic Kir channelopathies have shed light on novel pathophysiological mechanisms, including renal sodium and potassium handling, potassium shifting in skeletal muscles, and aldosterone production in the adrenal glands.	Potassium	148-157	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	25-28
24899236-5	2015	Here, we review several recent advances in Kir channels and their clinical implications in sodium and potassium homeostasis.	Potassium	102-111	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	43-46
25483891-0	2015	Mdm31 protein mediates sensitivity to potassium ionophores but does not regulate mitochondrial morphology or phospholipid trafficking in Schizosaccharomyces pombe.	Potassium	38-47	Mdm31p	Saccharomyces cerevisiae S288C	0-5
25645492-6	2015	Ghrelin elicited TTX-insensitive changes in dF/F indicative of rises in calcium, and a portion of these rises were independent of membrane depolarization, as they persisted in conditions of high extracellular potassium solutions and were found to involve SERCA-pump mediated intracellular calcium stores.	Potassium	209-218	ghrelin	Mus musculus	0-7
25716831-2	2015	We report here that BACE1 regulates neuronal excitability through an unorthodox, nonenzymatic interaction with members of the KCNQ (Kv7) family that give rise to the M-current, a noninactivating potassium current with slow kinetics.	Potassium	195-204	beta-site APP cleaving enzyme 1	Mus musculus	20-25
25844191-3	2015	Each (18-crown-6)potassium cation is in contact with the eta(3)-coordinating ligand of one cobaltate complex.	Potassium	17-26	endothelin receptor type A	Homo sapiens	57-60
25313717-3	2015	Flavonol-induced HSA (tryptophan) fluorescence quenching data yield the dynamic quenching constant (KD) as 5.42 x 10(3) M(-1) and the association constant (Ks) as 5.59 x 10(4) M(-1).	Potassium	156-158	albumin	Homo sapiens	17-20
25709906-7	2015	Furthermore, in the SV40-immortalized human corneal epithelial cells, NLRP3 was exclusively located in the nucleus, and treatment of the cells with high concentration of extracellular potassium (known as an inhibitor of NLRP3 activation) effectively drove NLRP3 back to the cytoplasm as reflected by both immunohistochemistry and Western blot.	Potassium	184-193	NLR family pyrin domain containing 3	Homo sapiens	70-75
25709906-7	2015	Furthermore, in the SV40-immortalized human corneal epithelial cells, NLRP3 was exclusively located in the nucleus, and treatment of the cells with high concentration of extracellular potassium (known as an inhibitor of NLRP3 activation) effectively drove NLRP3 back to the cytoplasm as reflected by both immunohistochemistry and Western blot.	Potassium	184-193	NLR family pyrin domain containing 3	Homo sapiens	220-225
25709906-7	2015	Furthermore, in the SV40-immortalized human corneal epithelial cells, NLRP3 was exclusively located in the nucleus, and treatment of the cells with high concentration of extracellular potassium (known as an inhibitor of NLRP3 activation) effectively drove NLRP3 back to the cytoplasm as reflected by both immunohistochemistry and Western blot.	Potassium	184-193	NLR family pyrin domain containing 3	Homo sapiens	220-225
25444851-7	2015	CONCLUSION: S3 mutations in KCNQ1 cause diverse kinetic defects in I(Ks), affecting opening and closing properties, and can account for LQT1 phenotypes.	Potassium	69-71	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	28-33
25685180-17	2015	CONCLUSIONS: In both cohorts, ADCs have decreased over time, though incidence of KS was higher at INI than VCCC.	Potassium	81-83	PHD finger protein 5A	Homo sapiens	98-101
25652939-9	2015	The Ka/Ks analysis showed that atp8 gene in the Crossoptilon likely experienced a strong selective pressure in adaptation to the plateau environment.	Potassium	7-9	ATP8	Crossoptilon auritum	31-35
24895271-2	2015	METHODS: Among participants of the Cardiovascular Health Study, a community-based cohort of older American adults, we examined a) cross-sectional associations between potassium and measures of insulin sensitivity and secretion estimated from oral glucose tolerance tests and b) longitudinal associations of serum and dietary potassium with diabetes risk.	Potassium	167-176	insulin	Homo sapiens	193-200
24895271-4	2015	In multivariate models, baseline serum and dietary potassium were both associated with lower insulin sensitivity and greater insulin secretion.	Potassium	51-60	insulin	Homo sapiens	93-100
25505069-5	2015	Nrf2 knockdown in LTC decreased expression of antioxidant genes and genes involved in KS pathogenesis such as the NAD(P)H quinone oxidase 1 (NQO1), gamma glutamylcysteine synthase heavy unit (gammaGCSH), the cysteine transporter (xCT), interleukin 6 (IL-6), and vascular endothelial growth factor A (VEGF-A) genes.	Potassium	86-88	NFE2 like bZIP transcription factor 2	Homo sapiens	0-4
25391539-8	2015	RESULTS: In the SOS reference study, subjects homozygous for the d3-GHR weighed ~4 kg more (P=0.011), and had larger waist-to-hip ratio (WHR, P=0.036), larger waist circumference (P=0.016), and more fat-free mass estimated from total body potassium (P=0.026) than grouped fl/d3 and fl/fl subjects (d3-recessive genetic model).	Potassium	239-248	growth hormone receptor	Homo sapiens	68-71
25243715-0	2015	Different spatial expressions of c-Fos in the nucleus of the solitary tract following taste stimulation with sodium, potassium, and ammonium ions in rats.	Potassium	117-126	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	33-38
25505069-16	2015	This study suggests that KSHV hijacks the host"s autophagic protein SQSTM1 to induce Nrf2 activation, thereby manipulating the infected host gene regulation to promote KS pathogenesis.	Potassium	25-27	sequestosome 1	Homo sapiens	68-74
25505069-16	2015	This study suggests that KSHV hijacks the host"s autophagic protein SQSTM1 to induce Nrf2 activation, thereby manipulating the infected host gene regulation to promote KS pathogenesis.	Potassium	25-27	NFE2 like bZIP transcription factor 2	Homo sapiens	85-89
25135348-4	2015	Significant associations were also found for ABCB11 and SLC30A8 single-nucleotide polymorphisms (SNPs) and glucose responses, and an SEC61A2 SNP with a potassium response to GIK.	Potassium	152-161	SEC61 translocon subunit alpha 2	Homo sapiens	133-140
25425491-3	2015	We show here that depletion of potassium from the medium or alteration of diverse regulatory pathways controlling potassium uptake, such as the Trk potassium transporters or the Pma1 H(+) -ATPase, triggers a response that mimics that of phosphate (Pi) deprivation, exemplified by accumulation of the high-affinity Pi transporter Pho84.	Potassium	31-40	phosphate transporter PHO84	Saccharomyces cerevisiae S288C	329-334
25425491-3	2015	We show here that depletion of potassium from the medium or alteration of diverse regulatory pathways controlling potassium uptake, such as the Trk potassium transporters or the Pma1 H(+) -ATPase, triggers a response that mimics that of phosphate (Pi) deprivation, exemplified by accumulation of the high-affinity Pi transporter Pho84.	Potassium	114-123	phosphate transporter PHO84	Saccharomyces cerevisiae S288C	329-334
25344677-1	2015	Potassium inwardly rectifying channel, subfamily J, member 1 (KCNJ1), as an ATP-dependent potassium channel, plays an essential role in potassium balance.	Potassium	90-99	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-60
25344677-1	2015	Potassium inwardly rectifying channel, subfamily J, member 1 (KCNJ1), as an ATP-dependent potassium channel, plays an essential role in potassium balance.	Potassium	90-99	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	62-67
25339702-1	2015	Despite similar stimulatory actions on the epithelial sodium channel (ENaC)-mediated sodium reabsorption in the distal tubule, insulin promotes kaliuresis, whereas insulin-like growth factor-1 (IGF-1) causes a reduction in urinary potassium levels.	Potassium	231-240	insulin-like growth factor 1	Mus musculus	164-192
25564733-8	2015	Altogether, our results suggest that amelioration of potassium leaks through potassium homeostasis mechanisms may minimize muscle damage of myopathies due to certain RyR1 mutations.	Potassium	53-62	ryanodine receptor 1, skeletal muscle	Mus musculus	166-170
25564733-8	2015	Altogether, our results suggest that amelioration of potassium leaks through potassium homeostasis mechanisms may minimize muscle damage of myopathies due to certain RyR1 mutations.	Potassium	77-86	ryanodine receptor 1, skeletal muscle	Mus musculus	166-170
25195496-0	2015	Understanding the effects of gamma-irradiation on potassium levels in red cell concentrates stored in SAG-M for neonatal red cell transfusion.	Potassium	50-59	S-antigen visual arrestin	Homo sapiens	102-105
25195496-3	2015	MATERIALS AND METHODS: The effects of irradiation on potassium release in RCCs stored in SAG-M were investigated under three scenarios.	Potassium	53-62	S-antigen visual arrestin	Homo sapiens	89-92
25833523-0	2015	Thiotaurine protects mouse cerebellar granule neurons from potassium deprivation-induced apoptosis by inhibiting the activation of caspase-3.	Potassium	59-68	caspase 3	Mus musculus	131-140
25339702-1	2015	Despite similar stimulatory actions on the epithelial sodium channel (ENaC)-mediated sodium reabsorption in the distal tubule, insulin promotes kaliuresis, whereas insulin-like growth factor-1 (IGF-1) causes a reduction in urinary potassium levels.	Potassium	231-240	insulin-like growth factor 1	Mus musculus	194-199
25339702-10	2015	We propose that IGF-1, by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the CCD.	Potassium	130-139	insulin-like growth factor 1	Mus musculus	16-21
25339702-10	2015	We propose that IGF-1, by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the CCD.	Potassium	130-139	chloride channel, voltage-sensitive Kb	Mus musculus	38-44
25288122-5	2015	The system is capable of quantification of potassium ions down to 0.31 muM.	Potassium	43-52	latexin	Homo sapiens	71-74
26491696-8	2015	In addition, SGK1 and Akt cooperatively regulate potassium secretion by renal outer medullary potassium channel (ROMK).	Potassium	49-58	serum/glucocorticoid regulated kinase 1	Homo sapiens	13-17
26491696-8	2015	In addition, SGK1 and Akt cooperatively regulate potassium secretion by renal outer medullary potassium channel (ROMK).	Potassium	49-58	AKT serine/threonine kinase 1	Homo sapiens	22-25
26491696-8	2015	In addition, SGK1 and Akt cooperatively regulate potassium secretion by renal outer medullary potassium channel (ROMK).	Potassium	49-58	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	113-117
25824645-0	2015	Effect of salt intake and potassium supplementation on urinary renalase and serum dopamine levels in Chinese adults.	Potassium	26-35	renalase, FAD dependent amine oxidase	Homo sapiens	63-71
25824645-1	2015	OBJECTIVE: The aim of our study was to assess the effects of altered salt and potassium intake on urinary renalase and serum dopamine levels in humans.	Potassium	78-87	renalase, FAD dependent amine oxidase	Homo sapiens	106-114
25824645-5	2015	During high-potassium intake, urinary renalase excretions were not significantly different from the high-salt diet, whereas they were significantly higher than the low-salt levels.	Potassium	12-21	renalase, FAD dependent amine oxidase	Homo sapiens	38-46
25824645-9	2015	CONCLUSIONS: The present study indicates that dietary salt intake and potassium supplementation increase urinary renalase and serum dopamine levels in Chinese subjects.	Potassium	70-79	renalase, FAD dependent amine oxidase	Homo sapiens	113-121
25552692-6	2015	Hence, this review summarizes what is known about the effect of PI3K and its downstream effectors, including Akt, on sodium, potassium, and calcium currents in cardiac myocytes.	Potassium	125-134	AKT serine/threonine kinase 1	Homo sapiens	109-112
24894912-9	2015	Moreover, beta1-AAs (0.001, 0.01, 0.1 mumol/L) dose-dependently increased the rapidly activating delayed rectifier potassium current (I Kr), but similarly decreased the slowly activating delayed rectifier potassium current (I Ks) and increased L-type calcium currents at the different concentrations.	Potassium	226-228	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	10-15
25447080-0	2015	Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current.	Potassium	80-89	discs large MAGUK scaffold protein 1	Mus musculus	56-61
25092804-0	2015	Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance.	Potassium	124-133	ciliary neurotrophic factor	Homo sapiens	0-27
25092804-0	2015	Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance.	Potassium	124-133	ciliary neurotrophic factor	Homo sapiens	29-33
26004420-7	2015	EXPERT OPINION: Although anti-hypertensive drugs armamentarium enumerates a plethora of therapeutic classes, including diuretics, the novel class of ROMK inhibitors may find a place in this crowded market, because of the diuretic/natriuretic effects, devoid of worrying influence on potassium balance.	Potassium	283-292	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	149-153
25374106-4	2015	However, in vivo electrochemical measures of potassium-evoked glutamate release in the CA1, but not the CA3 or dentate, was significantly elevated in AbetaPP/PS1 mice.	Potassium	45-54	carbonic anhydrase 1	Mus musculus	87-90
25841124-6	2015	In this study, we hypothesize that disrupted fission and fusion balance by increased Drp-1 and decreased Mfn2 expression in cardiomyocytes affects their contractility through alterations in the calcium and potassium concentrations.	Potassium	206-215	mitofusin 2	Mus musculus	105-109
25374106-4	2015	However, in vivo electrochemical measures of potassium-evoked glutamate release in the CA1, but not the CA3 or dentate, was significantly elevated in AbetaPP/PS1 mice.	Potassium	45-54	histocompatibility 2, class II antigen A, beta 1	Mus musculus	150-157
25374106-4	2015	However, in vivo electrochemical measures of potassium-evoked glutamate release in the CA1, but not the CA3 or dentate, was significantly elevated in AbetaPP/PS1 mice.	Potassium	45-54	presenilin 1	Mus musculus	158-161
25597679-4	2015	The MLK model was employed to simulate the adsorption kinetics of Cu(II), Co(II), Cd(II), Zn(II) and Ni(II) on MnO2 at pH3.2 or 3.3 to get the values of KS-kinetic.	Potassium	153-155	mitogen-activated protein kinase kinase kinase 13	Homo sapiens	4-7
25616098-1	2015	AIM: Polymorphisms in the mineralocorticoid receptor may affect urinary sodium and potassium excretion.	Potassium	83-92	nuclear receptor subfamily 3 group C member 2	Homo sapiens	26-52
27057553-0	2015	Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux.	Potassium	93-102	S100 calcium binding protein A8	Homo sapiens	13-19
25704028-0	2015	Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation.	Potassium	75-84	phosphatidylinositol-5-phosphate 4-kinase type 2 gamma	Homo sapiens	0-40
25704028-0	2015	Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation.	Potassium	75-84	potassium voltage-gated channel subfamily H member 2	Homo sapiens	70-74
25704028-1	2015	The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as alpha1-adrenergic and M1-muscarinic receptors (alpha1R and M1R, respectively), at least partly via the reduction of membrane phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2).	Potassium	44-53	potassium voltage-gated channel subfamily H member 2	Homo sapiens	38-42
26277930-0	2015	Common Variants in Serum/Glucocorticoid Regulated Kinase 1 (SGK1) and Blood Pressure Responses to Dietary Sodium or Potassium Interventions: A family-Based Association Study.	Potassium	116-125	serum/glucocorticoid regulated kinase 1	Homo sapiens	19-58
26277930-0	2015	Common Variants in Serum/Glucocorticoid Regulated Kinase 1 (SGK1) and Blood Pressure Responses to Dietary Sodium or Potassium Interventions: A family-Based Association Study.	Potassium	116-125	serum/glucocorticoid regulated kinase 1	Homo sapiens	60-64
26277930-2	2015	This study aimed to assess the association of common genetic variants in the SGK1 gene with BP responses to controlled dietary sodium or potassium interventions.	Potassium	137-146	serum/glucocorticoid regulated kinase 1	Homo sapiens	77-81
26277930-7	2015	However, the associations between selected SNPs in the SGK1 gene and BP responses to high-sodium or high-sodium plus potassium-supplementation intervention did not reach statistical significance.	Potassium	117-126	serum/glucocorticoid regulated kinase 1	Homo sapiens	55-59
25827151-4	2015	The pathophysiological mechanism comprises an increase in insulin levels, resulting in shifts of phosphate, potassium and magnesium into the intracellular environment, as well as fluid retention and relative deficiency of vitamin B1.	Potassium	108-117	insulin	Homo sapiens	58-65
26198561-2	2015	It has become more common in cardiovascular practice due to the growing population of patients with chronic kidney disease and the broad application of drugs that modulate renal elimination of potassium by reducing production of angiotensin II (angiotensin-converting enzyme inhibitors, direct renin inhibitors, beta-adrenergic receptor antagonists), blocking angiotensin II receptors (angiotensin receptor blockers), or antagonizing the action of aldosterone on mineralocorticoid receptors (mineralocorticoid receptor antagonists).	Potassium	193-202	angiotensinogen	Homo sapiens	229-243
25378686-0	2015	The major facilitator superfamily transporter ZIFL2 modulates cesium and potassium homeostasis in Arabidopsis.	Potassium	73-82	zinc induced facilitator-like 2	Arabidopsis thaliana	46-51
25331946-6	2014	We found that JAZ protects cerebellar granule neurons against potassium deprivation-induced death and cortical neurons from death resulting from oxidative stress.	Potassium	62-71	zinc finger protein 346	Homo sapiens	14-17
25807794-8	2015	CONCLUSION: LIG concentration-dependently protects against low potassium-induced apoptosis in CGN at least partly through GABAa receptor activation and its downstream IGF-1 signaling pathway.	Potassium	63-72	insulin-like growth factor 1	Rattus norvegicus	167-172
25355526-5	2014	In addition, 4 can subsequently be reduced with potassium to furnish again a Mg(I) compound, namely [K(thf)3]2[Mg2(L(1))2] (3).	Potassium	48-57	immunoglobulin kappa variable 1-16	Homo sapiens	115-119
25404286-6	2014	LT-induced NLRP1b inflammasome activation was shown to be impaired upon inhibition of potassium efflux, which is known to play a major role in NLRP3 inflammasome formation and ASC dimerization.	Potassium	86-95	NLR family, pyrin domain containing 1B	Mus musculus	11-17
25408964-5	2014	We find that the interaction of hUNG with undamaged DNA is electrostatically driven at a physiological concentration of potassium ions (DeltaGelect = -3.5 +- 0.5 kcal mol(-1)), with only a small nonelectrostatic contribution (DeltaGnon = -2.0 +- 0.2 kcal mol(-1)).	Potassium	120-129	uracil DNA glycosylase	Homo sapiens	32-36
25445147-5	2014	Importantly, we provided evidence to suggest that macrophage cell membrane binding to immobilized crystals was sufficient to induce IL-1beta release, and this activation of the NLRP3 inflammasome was inhibited by blocking potassium efflux.	Potassium	222-231	interleukin 1 beta	Homo sapiens	132-140
25480344-3	2014	Aim of the present post-hoc analysis of the PARAT trial was the description of serum potassium levels with certoparin compared to placebo.	Potassium	85-94	parathymosin	Homo sapiens	44-49
25404286-6	2014	LT-induced NLRP1b inflammasome activation was shown to be impaired upon inhibition of potassium efflux, which is known to play a major role in NLRP3 inflammasome formation and ASC dimerization.	Potassium	86-95	NLR family, pyrin domain containing 3	Mus musculus	143-148
25445147-5	2014	Importantly, we provided evidence to suggest that macrophage cell membrane binding to immobilized crystals was sufficient to induce IL-1beta release, and this activation of the NLRP3 inflammasome was inhibited by blocking potassium efflux.	Potassium	222-231	NLR family pyrin domain containing 3	Homo sapiens	177-182
25404286-6	2014	LT-induced NLRP1b inflammasome activation was shown to be impaired upon inhibition of potassium efflux, which is known to play a major role in NLRP3 inflammasome formation and ASC dimerization.	Potassium	86-95	PYD and CARD domain containing	Mus musculus	176-179
23386284-7	2014	Hypo-S increased the I(Ks) by 113.4%, whereas Hypo-S + 1 muM irbesartan and Hypo-S + 50 muM irbesartan increased the I(Ks) by only 74.5% and 70.3%, respectively.	Potassium	119-121	latexin	Homo sapiens	88-91
25273356-6	2014	SCH 66712 displays type I binding to CYP3A4 with a spectral binding constant (Ks) of 42.9 +- 2.9 microM.	Potassium	78-80	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	37-43
23386284-6	2014	RESULTS: Irbesartan (1-50 muM) attenuated the Hypo-S-induced increase in I(Ks) and shortening of APD90.	Potassium	75-77	latexin	Homo sapiens	26-29
23386284-2	2014	Blockade of angiotensin II subtype 1 receptors (AT(1)R) attenuates this increase in I(Ks).	Potassium	86-88	angiotensin II receptor type 1	Homo sapiens	12-54
25464889-6	2014	GALP (10(-10 )M and 10(-9 )M) induced intensified basal AVP release from the NH and Hth-NH complex as well as the release of potassium-evoked AVP from the Hth-NH.	Potassium	125-134	galanin-like peptide	Rattus norvegicus	0-4
25464889-6	2014	GALP (10(-10 )M and 10(-9 )M) induced intensified basal AVP release from the NH and Hth-NH complex as well as the release of potassium-evoked AVP from the Hth-NH.	Potassium	125-134	arginine vasopressin	Rattus norvegicus	142-145
25398734-3	2014	The role that modified sodium or potassium intake plays in influencing the renin-angiotensin system, arterial stiffness, and endothelial dysfunction remains of interest in current research.	Potassium	33-42	renin	Homo sapiens	75-80
24486303-4	2014	The importance of this interaction is clearly decreased during subsequent stages, during which endothelin-1 may participate in the genesis of ventricular tachycardia or fibrillation via other mechanisms; of these, the effects of endothelin-1 on repolarizing potassium currents and electrical conduction via gap junctions merit further research.	Potassium	258-267	endothelin 1	Homo sapiens	95-107
24486303-4	2014	The importance of this interaction is clearly decreased during subsequent stages, during which endothelin-1 may participate in the genesis of ventricular tachycardia or fibrillation via other mechanisms; of these, the effects of endothelin-1 on repolarizing potassium currents and electrical conduction via gap junctions merit further research.	Potassium	258-267	endothelin 1	Homo sapiens	229-241
25393291-4	2014	METHODS AND RESULTS: We show the impact of YxkO on the activity of SigB-dependent Pctc promoter and adaptation to osmotic and ethanol stress and potassium limitation respectively.	Potassium	145-154	NAD(P)H dehydratase	Bacillus subtilis subsp. subtilis str. 168	43-47
25228688-1	2014	KChIP3 (potassium channel interacting protein 3) is a calcium-binding protein that binds at the N terminus of the Kv4 voltage-gated potassium channel through interactions at two contact sites and has been shown to regulate potassium current gating kinetics as well as channel trafficking in cardiac and neuronal cells.	Potassium	8-17	potassium voltage-gated channel interacting protein 3	Homo sapiens	0-6
26021685-7	2014	RESULTS: After administration of 10 gram glucose and 10 units regular insulin bolus intravenously, a drastic and significant decreased of serum potassium from 5.73 +- 0.44 to 4.48 +- 0.06 mEq/L was noted.	Potassium	144-153	insulin	Homo sapiens	70-77
25355908-0	2014	Nitric oxide negatively regulates AKT1-mediated potassium uptake through modulating vitamin B6 homeostasis in Arabidopsis.	Potassium	48-57	K+ transporter 1	Arabidopsis thaliana	34-38
26021685-9	2014	CONCLUSIONS: An intravenous bolus of 10 units regular insulin with 10 gram glucose was able to decrease the serum -potassium level effectively and additionally increase serum glucose in LDLT patients.	Potassium	115-124	insulin	Homo sapiens	54-61
24463703-0	2014	Reduced excitability of gp130-deficient nociceptors is associated with increased voltage-gated potassium currents and Kcna4 channel upregulation.	Potassium	95-104	interleukin 6 signal transducer	Mus musculus	24-29
25220289-7	2014	Ka/Ks ratios indicated that Gadd45g1 and Gadd45g2 may have undergone a high number of mutations and have a divergence time of only about 68,000years, although Gadd45g homologs are highly conserved.	Potassium	3-5	uncharacterized protein LOC103396969	Cynoglossus semilaevis	28-36
25220289-7	2014	Ka/Ks ratios indicated that Gadd45g1 and Gadd45g2 may have undergone a high number of mutations and have a divergence time of only about 68,000years, although Gadd45g homologs are highly conserved.	Potassium	3-5	growth arrest and DNA-damage-inducible, gamma a	Cynoglossus semilaevis	41-49
25169970-0	2014	Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway.	Potassium	97-106	toll-like receptor 4	Rattus norvegicus	0-20
25169970-0	2014	Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway.	Potassium	97-106	interferon regulatory factor 3	Rattus norvegicus	132-136
25169970-0	2014	Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway.	Potassium	97-106	MYD88, innate immune signal transduction adaptor	Rattus norvegicus	151-156
25280426-1	2014	Refeeding syndrome (RFS) broadly encompasses a severe electrolyte disturbance (principally low serum concentrations of intracellular ions such as phosphate, magnesium, and potassium) and metabolic abnormalities in undernourished patients undergoing refeeding whether orally, enterally, or parenterally.	Potassium	172-181	FRTS1	Homo sapiens	20-23
24463703-4	2014	In this study, we show that nociceptor-specific deletion of gp130 alters excitability parameters that are linked to changes in the potassium conductance.	Potassium	131-140	interleukin 6 signal transducer	Mus musculus	60-65
24463703-7	2014	The main difference between gp130-deficient and control neurons was a significant increase in the conductance of both delayed rectifier as well as A-type potassium currents.	Potassium	154-163	interleukin 6 signal transducer	Mus musculus	28-33
25080489-0	2014	Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase.	Potassium	83-92	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-14
25318749-0	2014	Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration.	Potassium	24-33	ETS transcription factor ERG	Homo sapiens	19-23
25318749-2	2014	Ionic current carried by hERG channels (IhERG) is known to exhibit a paradoxical dependence on external potassium concentration ([K(+)]e), but effects of acute [K(+)]e changes on the response of IhERG to premature stimulation have not been characterized.	Potassium	104-113	ETS transcription factor ERG	Homo sapiens	25-29
25171201-1	2014	The neuropeptide nociceptin/orphanin FQ (N/OFQ) has been shown to inhibit delayed rectifier potassium current (IK) in acutely dissociated rat parietal cortical neurons.	Potassium	92-101	prepronociceptin	Rattus norvegicus	17-27
25171201-1	2014	The neuropeptide nociceptin/orphanin FQ (N/OFQ) has been shown to inhibit delayed rectifier potassium current (IK) in acutely dissociated rat parietal cortical neurons.	Potassium	92-101	prepronociceptin	Rattus norvegicus	28-39
25138250-2	2014	CPH showed potassium ion concentration - dependent erosion characteristics which ensured slow erosion in aqueous environment containing potassium ion at the physiological level.	Potassium	11-20	carboxypeptidase E	Rattus norvegicus	0-3
25138250-2	2014	CPH showed potassium ion concentration - dependent erosion characteristics which ensured slow erosion in aqueous environment containing potassium ion at the physiological level.	Potassium	136-145	carboxypeptidase E	Rattus norvegicus	0-3
25164821-1	2014	The Ste20-related kinase SPAK regulates sodium, potassium, and chloride transport in a variety of tissues.	Potassium	48-57	serine/threonine kinase 39	Homo sapiens	25-29
25080489-0	2014	Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase.	Potassium	83-92	angiotensin II receptor, type 1a	Mus musculus	130-133
25080489-3	2014	By means of intracellular microelectrode recordings we found that ANG II reduced gCl in the nanomolar range and in a concentration-dependent manner (EC50 = 0.06 muM) meanwhile increasing potassium conductance (gK).	Potassium	187-196	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	66-72
24895213-0	2014	Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.	Potassium	9-18	betaine--homocysteine S-methyltransferase	Homo sapiens	71-111
25044933-3	2014	The role of MLC1 and HEPACAM is unknown, although they have been related with the processes of cell-volume regulation and potassium siphoning by astrocytes.	Potassium	122-131	modulator of VRAC current 1	Homo sapiens	12-16
24955869-9	2014	On the other hand, we found a significant decrease of XIAP levels in cultured CGN maintained in chronic potassium deprivation, an apoptotic condition, suggesting a possible relationship between XIAP levels and neuronal viability.	Potassium	104-113	X-linked inhibitor of apoptosis	Rattus norvegicus	54-58
24955869-9	2014	On the other hand, we found a significant decrease of XIAP levels in cultured CGN maintained in chronic potassium deprivation, an apoptotic condition, suggesting a possible relationship between XIAP levels and neuronal viability.	Potassium	104-113	X-linked inhibitor of apoptosis	Rattus norvegicus	194-198
24955869-11	2014	The down-regulation of XIAP in CGN cultured under survival conditions (chronic potassium depolarization) induced a reduction of cell viability and an increment of apoptotic cells.	Potassium	79-88	X-linked inhibitor of apoptosis	Rattus norvegicus	23-27
25269074-10	2014	Application of PDF inhibited outward potassium or inward sodium currents, sometimes in the same neuron.	Potassium	37-46	peptide deformylase, mitochondrial	Homo sapiens	15-18
24840118-6	2014	Because TRPM4 is a Ca(2+) -activated monovalent-selective cation channel, these findings imply that TRPM4 contributes to potassium ion transport, essential for the signal transduction in IHCs and the formation of endolymph by marginal cells.	Potassium	121-130	transient receptor potential cation channel, subfamily M, member 4	Mus musculus	8-13
24840118-6	2014	Because TRPM4 is a Ca(2+) -activated monovalent-selective cation channel, these findings imply that TRPM4 contributes to potassium ion transport, essential for the signal transduction in IHCs and the formation of endolymph by marginal cells.	Potassium	121-130	transient receptor potential cation channel, subfamily M, member 4	Mus musculus	100-105
24895213-3	2014	Herein we report that BHMT is activated by potassium ions with an apparent K(M) for K+ of about 100 microM.	Potassium	43-52	betaine--homocysteine S-methyltransferase	Homo sapiens	22-26
24895213-8	2014	The potassium binding residues in BHMT partially overlap with the previously identified DGG (Asp26-Gly27-Gly28) fingerprint in the Pfam 02574 group of methyltransferases.	Potassium	4-13	betaine--homocysteine S-methyltransferase	Homo sapiens	34-38
24895213-10	2014	Together, the data herein indicate that the role of potassium ions in BHMT is structural and that potassium ion facilitates the specific binding of homocysteine to the active site of the enzyme.	Potassium	52-61	betaine--homocysteine S-methyltransferase	Homo sapiens	70-74
25086033-0	2014	Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.	Potassium	24-33	Wnk kinase	Drosophila melanogaster	51-54
25086309-3	2014	Regarding sodium- and potassium-coupled Cl(-) transport (NKCC1) both up- and downregulations have been proposed.	Potassium	22-31	solute carrier family 12 member 2	Homo sapiens	57-62
25037568-9	2014	In the KCNE1 distal C-terminus, the LQT mutation P127T suppressed yotiao-dependent cAMP-mediated upregulation of the I(KS) current, which was caused by reduced KCNQ1 phosphorylation at S27.	Potassium	119-121	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	7-12
25037568-9	2014	In the KCNE1 distal C-terminus, the LQT mutation P127T suppressed yotiao-dependent cAMP-mediated upregulation of the I(KS) current, which was caused by reduced KCNQ1 phosphorylation at S27.	Potassium	119-121	A-kinase anchoring protein 9	Homo sapiens	66-72
25037568-9	2014	In the KCNE1 distal C-terminus, the LQT mutation P127T suppressed yotiao-dependent cAMP-mediated upregulation of the I(KS) current, which was caused by reduced KCNQ1 phosphorylation at S27.	Potassium	119-121	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	160-165
25197769-2	2014	We synthesized a cation-substituted MOF, K2(H2adp)[Zn2(ox)3] 3H2O, where the ammonium ions in a well-defined hydrogen-bonding network are substituted with non-hydrogen-bonding potassium ions, without any apparent change in the crystal structure.	Potassium	176-185	lysine acetyltransferase 8	Homo sapiens	36-39
25352996-4	2014	Here, we report the rational design of structure-switching DNA aptamers, based on the thrombin binding aptamer (TBA), that bind potassium with affinities that bridge the gap between previously reported weak-binding and strong-binding aptamers.	Potassium	128-137	coagulation factor II, thrombin	Homo sapiens	86-94
25086033-0	2014	Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.	Potassium	24-33	serine/threonine kinase 39	Homo sapiens	55-59
25086033-0	2014	Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.	Potassium	24-33	frayed	Drosophila melanogaster	60-64
24927994-2	2014	Outward potassium currents mediated by two-pore-domain potassium (K2P) channels promote repolarization of excitable cells.	Potassium	8-17	keratin 76	Homo sapiens	66-69
24845199-3	2014	In the present study we analyze the effects of KB-R7943 on the ATP-dependent potassium current (IKATP) recorded by whole-cell patch-clamp in ventricular cardiomyocytes from a mammal (mouse) and a fish (crucian carp).	Potassium	77-86	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	96-101
25047526-8	2014	The reduction in renal potassium excretion due to inhibition of the renin-angiotensin-aldosterone system represents the most important mechanism by which drugs are known to cause hyperkalemia.	Potassium	23-32	renin	Homo sapiens	68-73
25047526-10	2014	Drugs that impair renal potassium excretion are mainly represented by angiotensin-converting enzyme inhibitors, angiotensin-II receptor blockers, direct renin inhibitors, nonsteroidal anti-inflammatory drugs, calcineurin inhibitors, heparin and derivatives, aldosterone antagonists, potassium-sparing diuretics, trimethoprim, and pentamidine.	Potassium	24-33	renin	Homo sapiens	153-158
25730969-2	2014	Inhibitory analysis of ATP-dependent potassium transport in mitochondria with polyclonal antibodies to calreticulin was carried out.	Potassium	37-46	calreticulin	Homo sapiens	103-115
25057880-0	2014	A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.	Potassium	142-151	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	8-13
25196520-0	2014	Functional cross-talk between the alpha1- and beta1-adrenergic receptors modulates the rapidly activating delayed rectifier potassium current in guinea pig ventricular myocytes.	Potassium	124-133	beta-1 adrenergic receptor	Cavia porcellus	34-72
24666922-10	2014	Serum potassium levels decreased similarly after insulin injection during both hypoglycaemia and euglycaemia.	Potassium	6-15	insulin	Homo sapiens	49-56
24297522-6	2014	Another THIK-2 mutant, in which the putative retention/retrieval signal RRR at positions 14-16 was replaced by AAA, produced a similar potassium current.	Potassium	135-144	potassium two pore domain channel subfamily K member 12	Homo sapiens	8-14
25092935-8	2014	Our most notable findings included the following: (1) monitoring of serum potassium concentrations identified unanticipated hypokalemia episodes, not recognized before standard work implementation, and earlier addition of potassium to fluids resulted in a notable reduction in hypokalemia; (2) improvements in insulin infusion management were associated with reduced duration of ICU stay; and (3) with overall improved DKA management and education, cerebral edema occurrence and bicarbonate use were reduced.	Potassium	74-83	insulin	Homo sapiens	310-317
25092935-8	2014	Our most notable findings included the following: (1) monitoring of serum potassium concentrations identified unanticipated hypokalemia episodes, not recognized before standard work implementation, and earlier addition of potassium to fluids resulted in a notable reduction in hypokalemia; (2) improvements in insulin infusion management were associated with reduced duration of ICU stay; and (3) with overall improved DKA management and education, cerebral edema occurrence and bicarbonate use were reduced.	Potassium	222-231	insulin	Homo sapiens	310-317
25089715-3	2014	The aim of this study was to evaluate the effect and specific underlying mechanism of BS, NaCl, and the mineral mixture (components of BS other than NaCl, including zinc, magnesium, and potassium, Mix) on IL-32 signaling using the human monocyte cell line, THP-1.	Potassium	186-195	interleukin 32	Homo sapiens	205-210
24875671-11	2014	There was a significant reduction in E-selectin following the high (Median = 5.96 ng/ml) vs the low potassium diet (Median = 6.24 ng/ml), z = -2.49, P = 0.013.	Potassium	100-109	selectin E	Homo sapiens	37-47
24840884-1	2014	PURPOSE OF REVIEW: The purpose of this review is to describe the renin-angiotensin-aldosterone system and its regulatory control of sodium, potassium, chloride, hydrogen ion, and water homeostasis through its effects on the expression and activity of distal renal tubular cotransporter proteins and to discuss the gene mutations encoding these structures that disturb the function of this system.	Potassium	140-149	renin	Homo sapiens	65-70
24947509-2	2014	Assembled with the beta-subunit KCNE1, Kv7.1 conducts the slowly activating potassium current IKs, which is one of the major currents underlying repolarization of the cardiac action potential.	Potassium	76-85	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	32-37
24947509-2	2014	Assembled with the beta-subunit KCNE1, Kv7.1 conducts the slowly activating potassium current IKs, which is one of the major currents underlying repolarization of the cardiac action potential.	Potassium	76-85	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	39-44
24798513-7	2014	Hcrt/Orx neurons are excited through block of a potassium conductance and release glutamate with their peptides in TMN.	Potassium	48-57	hypocretin neuropeptide precursor	Homo sapiens	0-4
25126967-6	2014	Exposing neuronal cultures grown in NGF to Epac2siRNAreduced the expression of Epac2, but not Epac1 and prevented the PGE2-induced augmentation of capsaicin and potassium-evoked CGRP release in sensory neurons and the PGE2-induced increase in the number of APs generated by a ramp of current.	Potassium	161-170	nerve growth factor	Rattus norvegicus	36-39
25126967-6	2014	Exposing neuronal cultures grown in NGF to Epac2siRNAreduced the expression of Epac2, but not Epac1 and prevented the PGE2-induced augmentation of capsaicin and potassium-evoked CGRP release in sensory neurons and the PGE2-induced increase in the number of APs generated by a ramp of current.	Potassium	161-170	Rap guanine nucleotide exchange factor 4	Rattus norvegicus	43-48
25126967-6	2014	Exposing neuronal cultures grown in NGF to Epac2siRNAreduced the expression of Epac2, but not Epac1 and prevented the PGE2-induced augmentation of capsaicin and potassium-evoked CGRP release in sensory neurons and the PGE2-induced increase in the number of APs generated by a ramp of current.	Potassium	161-170	Rap guanine nucleotide exchange factor 4	Rattus norvegicus	79-84
25126967-6	2014	Exposing neuronal cultures grown in NGF to Epac2siRNAreduced the expression of Epac2, but not Epac1 and prevented the PGE2-induced augmentation of capsaicin and potassium-evoked CGRP release in sensory neurons and the PGE2-induced increase in the number of APs generated by a ramp of current.	Potassium	161-170	calcitonin-related polypeptide alpha	Rattus norvegicus	178-182
24866132-8	2014	Patients with KCNJ5 mutations were more frequently female, diagnosed younger, and with higher minimal plasma potassium concentrations compared with CACNA1D mutation carriers or noncarriers.	Potassium	109-118	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	14-19
25254266-6	2014	A 1 muM LOD for sodium and a 1.6 muM LOD for potassium ions were revealed for the detector.	Potassium	45-54	latexin	Homo sapiens	4-7
25254266-6	2014	A 1 muM LOD for sodium and a 1.6 muM LOD for potassium ions were revealed for the detector.	Potassium	45-54	latexin	Homo sapiens	33-36
24694645-10	2014	Six SNPs in WNK1 (rs11064524, rs4980973, rs12581940, rs880054, rs953361, and rs10849582) were correlated with decreases in serum potassium.	Potassium	129-138	WNK lysine deficient protein kinase 1	Homo sapiens	12-16
24678923-1	2014	INTRODUCTION: KV 4 together with KV Channel-Interacting Protein 2 (KChIP2) mediate the fast recovering transient outward potassium current (I(to,f)) in the heart.	Potassium	121-130	Kv channel-interacting protein 2	Mus musculus	33-65
24678923-1	2014	INTRODUCTION: KV 4 together with KV Channel-Interacting Protein 2 (KChIP2) mediate the fast recovering transient outward potassium current (I(to,f)) in the heart.	Potassium	121-130	Kv channel-interacting protein 2	Mus musculus	67-73
24769160-10	2014	The addition of the PKA inhibitor KT5720, the MAP kinase inhibitor U0126, and the PI3 kinase inhibitor LY294002 abrogated the GPR3-mediated antiapoptotic effect in a potassium-deprivation model of apoptosis, whereas the PKC inhibitor Go6976 did not affect the antiapoptotic function of GPR3.	Potassium	166-175	G-protein coupled receptor 3	Mus musculus	126-130
24694645-13	2014	Multivariate stepwise linear regression analysis revealed that the changes in serum potassium levels were independently associated with the baseline potassium level (beta=-0.587, 95% confidence interval=-0.875--0.299, P=0.0001) and WNK1 rs4980973 (A/A and A/G vs. G/G, beta=-0.418, 95% confidence interval=-0.598--0.237, P=0.00002).	Potassium	84-93	WNK lysine deficient protein kinase 1	Homo sapiens	232-236
24694645-13	2014	Multivariate stepwise linear regression analysis revealed that the changes in serum potassium levels were independently associated with the baseline potassium level (beta=-0.587, 95% confidence interval=-0.875--0.299, P=0.0001) and WNK1 rs4980973 (A/A and A/G vs. G/G, beta=-0.418, 95% confidence interval=-0.598--0.237, P=0.00002).	Potassium	149-158	WNK lysine deficient protein kinase 1	Homo sapiens	232-236
24694645-14	2014	In conclusion, the baseline potassium level and the WNK1 rs4980973 polymorphism were independent predictors of decreases in serum potassium after short-term hydrochlorothiazide treatment in nondiabetic hypertensive patients.	Potassium	130-139	WNK lysine deficient protein kinase 1	Homo sapiens	52-56
24753196-2	2014	Body cell mass (BCM) assessment using total body potassium (TBK) measurements is considered the gold standard for assessing nutritional status.	Potassium	49-58	TNF receptor superfamily member 17	Homo sapiens	16-19
25077539-7	2014	This may explain why especially these cells appear to benefit from the preserved Kir4.1 expression in Muller cells, which should allow them to keep up their function in the context of spatial buffering of potassium.	Potassium	205-214	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	81-87
25056878-4	2014	When stimulated by potassium ions (K(+)), Panx1 formed a high-conductance channel of ~500 pS that was permeable to ATP.	Potassium	19-28	pannexin 1 L homeolog	Xenopus laevis	42-47
24974804-3	2014	Reduction of the azabutadienyl chelate boron dichloride [ArN C(R)CH C(R)]BCl2 (2, Ar=2,6-Me2 C6 H3 , R=tBu) with two equivalents of potassium yielded the novel 2-chloro-azaborolyl anion [ArNC(R)CHC(R)BCl]K(thf) (3) as a stable product in good yield.	Potassium	132-141	BCL2 apoptosis regulator	Homo sapiens	73-77
24862110-1	2014	Ion-selective organic electrochemical transistors with sensitivity to potassium approaching 50 muA dec(-1) are demonstrated.	Potassium	70-79	deleted in esophageal cancer 1	Homo sapiens	99-105
24785188-0	2014	Sodium and potassium regulate endothelial phospholipase C-gamma and Bmx.	Potassium	11-20	BMX non-receptor tyrosine kinase	Rattus norvegicus	68-71
25058146-0	2014	Effect of salt intake and potassium supplementation on serum renalase levels in Chinese adults: a randomized trial.	Potassium	26-35	renalase, FAD dependent amine oxidase	Homo sapiens	61-69
24143882-11	2014	The most compelling results were obtained with genes involved in potassium signaling pathways (e.g., KCNC1 and KCNG2).	Potassium	65-74	potassium voltage-gated channel subfamily C member 1	Homo sapiens	101-106
24143882-11	2014	The most compelling results were obtained with genes involved in potassium signaling pathways (e.g., KCNC1 and KCNG2).	Potassium	65-74	potassium voltage-gated channel modifier subfamily G member 2	Homo sapiens	111-116
23844633-4	2014	Both types of LQTS can be caused by mutations in channel genes (e.g. KCNQ1) responsible for potassium homeostasis in cardiac myocytes and cochlea.	Potassium	92-101	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	69-74
24501278-9	2014	Discovery of a functionally relevant novel de novo variant, coupled with physiological evidence that the mutant protein disrupts potassium current inactivation, strongly supports KCND2 as the causal gene for epilepsy in this family.	Potassium	129-138	potassium voltage-gated channel subfamily D member 2	Homo sapiens	179-184
25058146-7	2014	No significant correlation was found between the renalase level and BP among the different dietary interventions.The present study indicates that variations in dietary salt intake and potassium supplementation affect the serum renalase concentration in Chinese subjects.	Potassium	184-193	renalase, FAD dependent amine oxidase	Homo sapiens	227-235
24840790-2	2014	To identify the risk gene within the region we studied the potassium inwardly-rectifying channel J5 (KCNJ5) gene in a sample of 170 nuclear families with TS.	Potassium	59-68	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	101-106
24573316-0	2014	Relation between BK-alpha/beta4-mediated potassium secretion and ENaC-mediated sodium reabsorption.	Potassium	41-50	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	65-69
24573316-11	2014	Thus, the enhanced effect of amiloride on potassium secretion in wild-type compared to knockout mice on the alkaline diet clarify a BK- alpha/beta4-mediated potassium secretory pathway in intercalated cells driven by ENaC-mediated sodium reabsorption linked to bicarbonate secretion.	Potassium	157-166	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	217-221
25058146-5	2014	Renalase levels decreased with the change from the low-salt to high-salt diet, whereas dietary potassium prevented the decrease in serum renalase induced by the high-salt diet.	Potassium	95-104	renalase, FAD dependent amine oxidase	Homo sapiens	137-145
24361620-8	2014	The binding of azoles to zebrafish CYP51 gave KS (dissociation constant) values of 0.26muM for ketoconazole and 0.64muM for propiconazole.	Potassium	46-48	cytochrome P450, family 51	Danio rerio	35-40
24748657-3	2014	The present investigation used photolysis of two caged opioid ligands to examine the kinetics of MOR-induced potassium conductance before and after MOR desensitization.	Potassium	109-118	opioid receptor mu 1	Homo sapiens	97-100
24619705-6	2014	Potassium efflux, activation of P2X7 receptor and intracellular reactive oxygen speciesare also important factors required for fullerenols-induced IL-1beta release.	Potassium	0-9	interleukin 1 beta	Mus musculus	147-155
24894994-4	2014	Lowering the concentration of extracellular potassium, a condition that reduces neuronal excitability, stimulated depletion of intracellular Ca(2+) stores, resulted in the relocalization of the ER Ca(2+) sensor STIM1 into punctate clusters consistent with multimerization and accumulation at junctions between the ER and plasma membrane, and induced a Ca(2+) influx with characteristics of SOCE.	Potassium	44-53	stromal interaction molecule 1	Homo sapiens	211-216
24894994-5	2014	Compounds that block SOCE prevented the ubiquitylation and degradation of Sp4 in neurons exposed to a low concentration of extracellular potassium.	Potassium	137-146	Sp4 transcription factor	Homo sapiens	74-77
24748648-8	2014	Moreover, we corroborated the ciliary localization of the potassium-dependent Na(+)/Ca(2+) exchanger (NCKX) 4 and the plasma membrane Ca(2+)-ATPase 1 (PMCA1) involved in olfactory signal termination, and we detected for the first time NCKX2 in olfactory cilia.	Potassium	58-67	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	Mus musculus	78-109
24748648-8	2014	Moreover, we corroborated the ciliary localization of the potassium-dependent Na(+)/Ca(2+) exchanger (NCKX) 4 and the plasma membrane Ca(2+)-ATPase 1 (PMCA1) involved in olfactory signal termination, and we detected for the first time NCKX2 in olfactory cilia.	Potassium	58-67	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	Mus musculus	235-240
32261727-3	2014	In the present study, a synthetic peptide whose sequence is from the fourth transmembrane segment of TRPV4 is found that is capable of self-assembling into potassium (K+)-like ion channels designated as TRP-PK1 in the membranes of liposomes and live cells.	Potassium	156-165	transient receptor potential cation channel subfamily V member 4	Homo sapiens	101-106
24738991-8	2014	Multivariate analysis adjusted for age and fibrinogen showed that in MM patients elevated peak thrombin levels determine Ks and D-Dmax , while thrombin-activatable fibrinolysis inhibitor (TAFI) activity predicts Ks , t50% , D-Drate and lag phase.	Potassium	121-123	coagulation factor II, thrombin	Homo sapiens	95-103
24671621-9	2014	Our findings suggest that hair mineral concentrations, such as calcium, magnesium, zinc, sodium, and potassium concentrations, may play a role in the development of insulin resistance.	Potassium	101-110	insulin	Homo sapiens	165-172
28510183-5	2014	Many studies have also demonstrated that CFTR also regulates channel pore opening and the transport of sodium, chloride and potassium.	Potassium	124-133	CF transmembrane conductance regulator	Homo sapiens	41-45
24738991-8	2014	Multivariate analysis adjusted for age and fibrinogen showed that in MM patients elevated peak thrombin levels determine Ks and D-Dmax , while thrombin-activatable fibrinolysis inhibitor (TAFI) activity predicts Ks , t50% , D-Drate and lag phase.	Potassium	212-214	carboxypeptidase B2	Homo sapiens	143-186
24738991-8	2014	Multivariate analysis adjusted for age and fibrinogen showed that in MM patients elevated peak thrombin levels determine Ks and D-Dmax , while thrombin-activatable fibrinolysis inhibitor (TAFI) activity predicts Ks , t50% , D-Drate and lag phase.	Potassium	212-214	carboxypeptidase B2	Homo sapiens	188-192
24916350-9	2014	The subcellular colocalization of Kir4.1 and AQP4 in epithelial supporting cells indicates functional coupling of potassium and water flow in the cochlea.	Potassium	114-123	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	34-40
24916350-9	2014	The subcellular colocalization of Kir4.1 and AQP4 in epithelial supporting cells indicates functional coupling of potassium and water flow in the cochlea.	Potassium	114-123	aquaporin 4	Homo sapiens	45-49
24525029-6	2014	Additionally, exogenous cystine crystals were internalized by monocytes, and inhibition of phagocytosis, cathepsin B leakage, generation of reactive oxygen species, and potassium efflux reduced cystine crystal-induced IL-1beta secretion.	Potassium	169-178	interleukin 1 beta	Homo sapiens	218-226
24712483-2	2014	Recent studies indicate that AQP4 regulates various biological functions of astrocytes, including maintaining CNS water balance, spatial buffering of extracellular potassium, calcium signal transduction, regulation of neurotransmission, synaptic plasticity, and adult neurogenesis, while under neuropathological conditions, AQP4 has a role in astrogliosis and proinflammatory cytokine secretion.	Potassium	164-173	aquaporin 4	Homo sapiens	29-33
24836577-4	2014	In mice with cardiac Bin1 deletion, T-tubule folding is decreased, which does not change overall cardiomyocyte morphology but leads to free diffusion of local extracellular calcium and potassium ions, prolonging action-potential duration and increasing susceptibility to ventricular arrhythmias.	Potassium	185-194	bridging integrator 1	Mus musculus	21-25
24855268-5	2014	RNA interference with FoxP expression in alphabeta core Kenyon cells, or the overexpression of a potassium conductance in these neurons, recapitulated the FoxP mutant phenotype.	Potassium	97-106	Forkhead box P	Drosophila melanogaster	155-159
24831221-2	2014	In most vertebrates, including humans, Muller cells abundantly express Kir4.1 inwardly rectifying potassium channels responsible for hyperpolarized membrane potential and for various vital functions such as potassium buffering and glutamate clearance; inter-species differences in Kir4.1 expression were, however, observed.	Potassium	98-107	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	71-77
24831221-2	2014	In most vertebrates, including humans, Muller cells abundantly express Kir4.1 inwardly rectifying potassium channels responsible for hyperpolarized membrane potential and for various vital functions such as potassium buffering and glutamate clearance; inter-species differences in Kir4.1 expression were, however, observed.	Potassium	98-107	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	281-287
24655003-5	2014	Insulin- and low-potassium diet-induced NCC phosphorylation were abolished in WNK4-/- mice, establishing that both signals to NCC were mediated by WNK4.	Potassium	17-26	WNK lysine deficient protein kinase 4	Mus musculus	78-82
24655003-5	2014	Insulin- and low-potassium diet-induced NCC phosphorylation were abolished in WNK4-/- mice, establishing that both signals to NCC were mediated by WNK4.	Potassium	17-26	WNK lysine deficient protein kinase 4	Mus musculus	147-151
24869750-15	2014	This is based on an informal indirect comparison of results observed in other Cochrane reviews on ACE inhibitors, ARBs and renin inhibitors compared with placebo, which used similar inclusion/exclusion criteria to the present review.Thiazides reduced potassium, increased uric acid and increased total cholesterol and triglycerides.	Potassium	251-260	angiotensin I converting enzyme	Homo sapiens	98-101
24803536-2	2014	WNK1 is at the top of a kinase cascade, leading to phosphorylation of several cotransporters, in particular those transporting sodium, potassium, and chloride (NKCC), sodium and chloride (NCC), and potassium and chloride (KCC).	Potassium	135-144	WNK lysine deficient protein kinase 1	Homo sapiens	0-4
24606883-7	2014	In vitro experiments showed that extracellular adenosine triphosphate (ATP) induced inflammasome activation in CD epithelial cells through P2X7-potassium efflux and reactive oxygen species-dependent pathways.	Potassium	144-153	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	139-143
24594434-8	2014	Further studies using HEK-293 cells overexpressing SVCT2 at the plasma membrane revealed that the altered kinetic properties of mitochondrial SVCT2 are due to the ionic intracellular microenvironment (low in sodium and high in potassium), with potassium acting as a concentration-dependent inhibitor of SVCT2.	Potassium	227-236	solute carrier family 23 member 2	Homo sapiens	51-56
24590823-1	2014	Previously we observed that capsaicin, a transient receptor potential vanilloid 1 (TRPV1) receptor activator, inhibited transient potassium current (IA) in capsaicin-sensitive and capsaicin-insensitive trigeminal ganglion (TG) neurons from rats.	Potassium	130-139	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	41-81
24590823-1	2014	Previously we observed that capsaicin, a transient receptor potential vanilloid 1 (TRPV1) receptor activator, inhibited transient potassium current (IA) in capsaicin-sensitive and capsaicin-insensitive trigeminal ganglion (TG) neurons from rats.	Potassium	130-139	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	83-88
24594434-10	2014	Overall, our data indicate that intracellular SVCT2 is localized in mitochondria, is sensitive to an intracellular microenvironment low in sodium and high in potassium, and functions as a low-affinity ascorbic acid transporter.	Potassium	158-167	solute carrier family 23 member 2	Homo sapiens	46-51
24594434-8	2014	Further studies using HEK-293 cells overexpressing SVCT2 at the plasma membrane revealed that the altered kinetic properties of mitochondrial SVCT2 are due to the ionic intracellular microenvironment (low in sodium and high in potassium), with potassium acting as a concentration-dependent inhibitor of SVCT2.	Potassium	227-236	solute carrier family 23 member 2	Homo sapiens	142-147
24594434-8	2014	Further studies using HEK-293 cells overexpressing SVCT2 at the plasma membrane revealed that the altered kinetic properties of mitochondrial SVCT2 are due to the ionic intracellular microenvironment (low in sodium and high in potassium), with potassium acting as a concentration-dependent inhibitor of SVCT2.	Potassium	227-236	solute carrier family 23 member 2	Homo sapiens	142-147
24509840-1	2014	TWIK-related K(+) 1 (TREK1) potassium channels are members of the two-pore domain potassium channel family and contribute to background potassium conductances in many cell types, where their activity can be regulated by a variety of physiologic and pharmacologic mediators.	Potassium	28-37	potassium two pore domain channel subfamily K member 2	Homo sapiens	0-19
24048291-9	2014	Plasma renin activity and serum aldosterone both increased with potassium (P=0.001 and P=0.048 respectively).	Potassium	64-73	renin	Homo sapiens	7-12
24886734-7	2014	Protein, vitamin B12, zinc, potassium and dairy intake were all positively correlated with higher BMD while dairy and potassium intakes also inversely correlated with CTX.	Potassium	118-127	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	167-170
24046152-10	2014	The electrophysiological study showed that leptin increases the fast transient outward potassium current amplitudes and densities shortening action potential duration.	Potassium	87-96	leptin	Rattus norvegicus	43-49
25016399-8	2014	Although approximately 70% of patients with uncontrolled TRH have estimated glomerular filtration rate of 50 or greater and a serum potassium level of 4.5 or less, which are associated with a low risk for hyperkalemia, only a small percentage receive a mineralocorticoid-receptor antagonist.	Potassium	132-141	thyrotropin releasing hormone	Homo sapiens	57-60
25016402-9	2014	The adverse electrolyte and renal function side effects with aldosterone-receptor antagonists are not uncommon in at-risk patients, such as those with chronic kidney disease, and require that dosing be mindful of the tendency of these drugs to importantly increase serum potassium levels.	Potassium	271-280	nuclear receptor subfamily 3 group C member 2	Homo sapiens	61-81
24509840-1	2014	TWIK-related K(+) 1 (TREK1) potassium channels are members of the two-pore domain potassium channel family and contribute to background potassium conductances in many cell types, where their activity can be regulated by a variety of physiologic and pharmacologic mediators.	Potassium	28-37	potassium two pore domain channel subfamily K member 2	Homo sapiens	21-26
24699751-1	2014	The Arabidopsis thaliana K(+) transporter 1 (AKT1) participates in the maintenance of an adequate cell potassium (K(+)) concentration.	Potassium	103-112	K+ transporter 1	Arabidopsis thaliana	4-43
24517838-3	2014	Zero-net flux microdialysis results showed that female BDNF(+/-) mice had increased striatal extracellular dopamine levels, while stimulated regional release by high potassium concentrations potentiated dopamine release through vesicular-mediated depolarization.	Potassium	166-175	brain derived neurotrophic factor	Mus musculus	55-59
24703839-4	2014	SOD1(A4V/+) ALS patient-derived motor neurons have reduced delayed-rectifier potassium current amplitudes relative to control-derived motor neurons, a deficit that may underlie their hyperexcitability.	Potassium	77-86	superoxide dismutase 1	Homo sapiens	0-4
24719109-2	2014	However, despite an abundance of evidence demonstrating that KCNQ2/3 heteromers underlie critical potassium conductances, it is unknown whether KCNQ2, KCNQ3, or both are obligatory for maintaining normal pyramidal neuron excitability.	Potassium	98-107	potassium voltage-gated channel, subfamily Q, member 2	Mus musculus	61-66
24694658-3	2014	Here we show that the inhibition of Panx1 by ATP is abrogated by increased extracellular potassium ion concentration ([K(+)]o) in a dose-dependent manner.	Potassium	89-98	pannexin 1	Homo sapiens	36-41
24699751-1	2014	The Arabidopsis thaliana K(+) transporter 1 (AKT1) participates in the maintenance of an adequate cell potassium (K(+)) concentration.	Potassium	103-112	K+ transporter 1	Arabidopsis thaliana	45-49
24721657-1	2014	Co-assembly of KCNQ1 with KCNE1 generates the IKS potassium current that is vital for the proper repolarization of the cardiac action potential.	Potassium	50-59	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	15-20
24357532-6	2014	KCNQ1 mutation carriers showed increased insulin release (area under the curve 45.6 +- 6.3 vs. 26.0 +- 2.8 min   nmol/L insulin) and beta-cell glucose sensitivity and had lower levels of plasma glucose and serum potassium upon oral glucose stimulation and increased hypoglycemic symptoms.	Potassium	212-221	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-5
24357532-8	2014	The phenotype of patients with KCNQ1 LQTS, caused by mutations in KCNQ1, includes, besides long QT, hyperinsulinemia, clinically relevant symptomatic reactive hypoglycemia, and low potassium after an oral glucose challenge, suggesting that KCNQ1 mutations may explain some cases of "essential" reactive hypoglycemia.	Potassium	181-190	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	31-36
24357532-8	2014	The phenotype of patients with KCNQ1 LQTS, caused by mutations in KCNQ1, includes, besides long QT, hyperinsulinemia, clinically relevant symptomatic reactive hypoglycemia, and low potassium after an oral glucose challenge, suggesting that KCNQ1 mutations may explain some cases of "essential" reactive hypoglycemia.	Potassium	181-190	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	66-71
24357532-8	2014	The phenotype of patients with KCNQ1 LQTS, caused by mutations in KCNQ1, includes, besides long QT, hyperinsulinemia, clinically relevant symptomatic reactive hypoglycemia, and low potassium after an oral glucose challenge, suggesting that KCNQ1 mutations may explain some cases of "essential" reactive hypoglycemia.	Potassium	181-190	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	66-71
24721657-1	2014	Co-assembly of KCNQ1 with KCNE1 generates the IKS potassium current that is vital for the proper repolarization of the cardiac action potential.	Potassium	50-59	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	26-31
24388921-0	2014	Inflammation enhanced brain-derived neurotrophic factor-induced suppression of the voltage-gated potassium currents in small-diameter trigeminal ganglion neurons projecting to the trigeminal nucleus interpolaris/caudalis transition zone.	Potassium	97-106	brain-derived neurotrophic factor	Rattus norvegicus	22-55
24494598-7	2014	Delayed rectifier potassium current is diminished in hippocampal neurons cultured from Kv2.1(-/-) animals.	Potassium	18-27	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	87-92
24258360-6	2014	The permeability coefficient Ks decreased significantly after FVIII treatment.	Potassium	29-31	coagulation factor VIII	Homo sapiens	62-67
24258360-7	2014	Ks correlated significantly with FVIII levels and dosage, and with ETP, OHP and levels of TAFI.	Potassium	0-2	coagulation factor VIII	Homo sapiens	33-38
24258360-7	2014	Ks correlated significantly with FVIII levels and dosage, and with ETP, OHP and levels of TAFI.	Potassium	0-2	carboxypeptidase B2	Homo sapiens	90-94
24643009-4	2014	In particular, we study the coordination of the different ligands, the gating mechanism and the location of the proton and potassium binding sites in EAAT3.	Potassium	123-132	solute carrier family 1 member 1	Homo sapiens	150-155
24643009-7	2014	Finally, we perform free energy calculations to locate the potassium binding site in EAAT3, and find a high-affinity site that overlaps with the Na1 and Na3 sites in GltPh.	Potassium	59-68	solute carrier family 1 member 1	Homo sapiens	85-90
24606761-1	2014	BACKGROUND: The human ether-a-go-go related gene 1 (hERG1), which codes for a potassium ion channel, is a key element in the cardiac delayed rectified potassium current, IKr, and plays an important role in the normal repolarization of the heart"s action potential.	Potassium	78-87	potassium voltage-gated channel subfamily H member 2	Homo sapiens	52-57
23912897-5	2014	The MMP23 pro-domain can trap Kv1.3 but not closely-related Kv1.2 channels in the endoplasmic reticulum, preventing their passage to the cell surface, while the TxD can bind to the channel pore and block the passage of potassium ions.	Potassium	219-228	matrix metallopeptidase 23B	Homo sapiens	4-9
24203997-5	2014	Of note, mTORC1 activation also reduced the expression of serum- and glucocorticoid-inducible kinase 1, a crucial regulator of potassium homeostasis in the kidney, and decreased the expression and/or activity of epithelial sodium channel-alpha, renal outer medullary potassium channel, and Na(+), K(+)-ATPase in the CD, which probably contributed to the aldosterone resistance and hyperkalemia in these mice.	Potassium	127-136	CREB regulated transcription coactivator 1	Mus musculus	9-15
23405890-8	2014	With the reduction in serum potassium level, participants have larger waist circumference (WC) and more severe insulin resistance.	Potassium	28-37	insulin	Homo sapiens	111-118
23405890-10	2014	In logistic regression analysis, compared with subjects in the highest quartile of serum potassium level, the adjusted odds ratios (ORs) in the lowest quartile was 1 33 [95% confidence interval (CI), 1 11-1 60] for NAFLD, 1 81 (95% CI, 1 49-2 19) for insulin resistance and 1 58 (95% CI, 1 30-1 93) for central obesity.	Potassium	89-98	insulin	Homo sapiens	251-258
23405890-11	2014	In subgroup analysis after multiple adjustments, significant relation between serum potassium level and prevalent NAFLD was detected in women, younger subjects, those with insulin resistance and those with central obesity, respectively.	Potassium	84-93	insulin	Homo sapiens	172-179
24337990-9	2014	Denuder-fitted PM1 sampler can serve as a useful sampling tool in estimating the true values for nitrate, ammonium, potassium, sodium and WSOC present in the ambient PM.	Potassium	116-125	transmembrane protein 11	Homo sapiens	15-18
24520048-4	2014	Here, we demonstrate the use of NMR spectroscopy to characterise binding of ammonium ions to two different enzymes: human histone deacetylase 8 (HDAC8), which is activated allosterically by potassium, and the bacterial Hsp70 homologue DnaK, for which potassium is an integral part of the active site.	Potassium	190-199	histone deacetylase 8	Homo sapiens	122-143
24520048-4	2014	Here, we demonstrate the use of NMR spectroscopy to characterise binding of ammonium ions to two different enzymes: human histone deacetylase 8 (HDAC8), which is activated allosterically by potassium, and the bacterial Hsp70 homologue DnaK, for which potassium is an integral part of the active site.	Potassium	190-199	histone deacetylase 8	Homo sapiens	145-150
24520048-4	2014	Here, we demonstrate the use of NMR spectroscopy to characterise binding of ammonium ions to two different enzymes: human histone deacetylase 8 (HDAC8), which is activated allosterically by potassium, and the bacterial Hsp70 homologue DnaK, for which potassium is an integral part of the active site.	Potassium	251-260	histone deacetylase 8	Homo sapiens	122-143
24520048-4	2014	Here, we demonstrate the use of NMR spectroscopy to characterise binding of ammonium ions to two different enzymes: human histone deacetylase 8 (HDAC8), which is activated allosterically by potassium, and the bacterial Hsp70 homologue DnaK, for which potassium is an integral part of the active site.	Potassium	251-260	histone deacetylase 8	Homo sapiens	145-150
24520048-4	2014	Here, we demonstrate the use of NMR spectroscopy to characterise binding of ammonium ions to two different enzymes: human histone deacetylase 8 (HDAC8), which is activated allosterically by potassium, and the bacterial Hsp70 homologue DnaK, for which potassium is an integral part of the active site.	Potassium	251-260	heat shock protein family A (Hsp70) member 4	Homo sapiens	219-224
24318194-9	2014	INTERPRETATION: The development of severe epilepsy and cognitive decline in children carrying 5 of the 7 studied KCNQ2 mutations can be related to a dominant-negative reduction of the resulting potassium current at subthreshold membrane potentials.	Potassium	194-203	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	113-118
24203997-2	2014	However, the role of mTOR in renal potassium excretion and hyperkalemia is not known.	Potassium	35-44	mechanistic target of rapamycin kinase	Mus musculus	21-25
24203997-7	2014	Overall, this study identifies a novel function of mTORC1 in regulating potassium homeostasis and demonstrates that loss of TSC1 and activation of mTORC1 results in dedifferentiation and dysfunction of the CD and causes hyperkalemia.	Potassium	72-81	CREB regulated transcription coactivator 1	Mus musculus	51-57
24203997-7	2014	Overall, this study identifies a novel function of mTORC1 in regulating potassium homeostasis and demonstrates that loss of TSC1 and activation of mTORC1 results in dedifferentiation and dysfunction of the CD and causes hyperkalemia.	Potassium	72-81	TSC complex subunit 1	Mus musculus	124-128
24506953-6	2014	Stimulation with high potassium induced calcium-dependent and reversible CGRP release.	Potassium	22-31	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	73-77
24138091-7	2014	HS could also activate MaxiK channels to promote the efflux of potassium ions from cells, as measured by the elevated activity of caspase-1, whereas this was significantly abolished by treatment with paxilline, a specific blocker of the MaxiK channel.	Potassium	63-72	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	23-28
24138091-7	2014	HS could also activate MaxiK channels to promote the efflux of potassium ions from cells, as measured by the elevated activity of caspase-1, whereas this was significantly abolished by treatment with paxilline, a specific blocker of the MaxiK channel.	Potassium	63-72	caspase 1	Homo sapiens	130-139
24138091-7	2014	HS could also activate MaxiK channels to promote the efflux of potassium ions from cells, as measured by the elevated activity of caspase-1, whereas this was significantly abolished by treatment with paxilline, a specific blocker of the MaxiK channel.	Potassium	63-72	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	237-242
24134393-7	2014	Impairment of the CMR1 activity alters root growth through aberrant activity of the root meristem, and modifies potassium concentration and hormonal balance (ethylene production and auxin accumulation).	Potassium	112-121	hypothetical protein	Arabidopsis thaliana	18-22
24238269-7	2014	However, levels of extracellular IL-1beta were greatly increased by subsequent treatment with the potassium-proton ionophore Adenosine triphosphate (ATP) or nigericin; an effect that was dependent on active caspase-1.	Potassium	98-107	interleukin 1 beta	Homo sapiens	33-41
24238269-7	2014	However, levels of extracellular IL-1beta were greatly increased by subsequent treatment with the potassium-proton ionophore Adenosine triphosphate (ATP) or nigericin; an effect that was dependent on active caspase-1.	Potassium	98-107	caspase 1	Homo sapiens	207-216
24408119-0	2014	Serum potassium in dual renin-angiotensin-aldosterone system blockade.	Potassium	6-15	renin	Homo sapiens	24-29
23884315-7	2014	The mechanism of P. acnes-induced NLRP3 activation and subsequent IL-1beta secretion was found to involve potassium efflux.	Potassium	106-115	NLR family pyrin domain containing 3	Homo sapiens	34-39
23884315-7	2014	The mechanism of P. acnes-induced NLRP3 activation and subsequent IL-1beta secretion was found to involve potassium efflux.	Potassium	106-115	interleukin 1 beta	Homo sapiens	66-74
25483840-4	2014	We report here that guanine-rich TFOs partially substituted with 8-aza-7-deaza-guanine (PPG) have improved target site binding in potassium compared with TFOs containing the natural guanine base.	Potassium	130-139	serglycin	Homo sapiens	88-91
24478370-5	2014	In addition, we show that enhanced intracellular Ca(2+) responses to depolarization with potassium are prevented by the treatment with the tPA-neutralizing antibody in FMRP-deficient cells during early neural progenitor differentiation.	Potassium	89-98	plasminogen activator, tissue	Mus musculus	139-142
24478370-5	2014	In addition, we show that enhanced intracellular Ca(2+) responses to depolarization with potassium are prevented by the treatment with the tPA-neutralizing antibody in FMRP-deficient cells during early neural progenitor differentiation.	Potassium	89-98	fragile X messenger ribonucleoprotein 1	Mus musculus	168-172
24369856-2	2014	Although the epitaxially guided collagen assembly mediated by potassium ion on mica surface has been reported several times over these years, specific effects of anions in this field has never been surveyed and discussed before now.	Potassium	62-71	MHC class I polypeptide-related sequence A	Homo sapiens	79-83
24233492-6	2014	A significant decrease in a voltage-dependent K(+) channel, Kv1.5 protein, and an increase in intracellular potassium levels were demonstrated in Nox1(-/Y) PASMCs.	Potassium	108-117	NADPH oxidase 1	Mus musculus	146-150
24233492-8	2014	CONCLUSIONS: These findings suggest a critical role for NOX1 in cellular apoptosis by regulating Kv1.5 and intracellular potassium levels.	Potassium	121-130	NADPH oxidase 1	Mus musculus	56-60
24388850-9	2014	Ka/Ks analyses indicate relatively rapid evolution of GEX2, like other proteins involved in male and female interactions.	Potassium	3-5	gamete expressed 2	Arabidopsis thaliana	54-58
25693308-1	2014	This study explored the mechanism of electro-acupuncture (EA) at PC6 to improve the heart function by regulating the cardiac transient outward potassium current (= Ito) channel in myocardial ischemia (MI).	Potassium	143-152	proprotein convertase subtilisin/kexin type 5	Rattus norvegicus	65-68
24021239-0	2014	Role of Saccharomyces cerevisiae Trk1 in stabilization of intracellular potassium content upon changes in external potassium levels.	Potassium	72-81	Trk1p	Saccharomyces cerevisiae S288C	33-37
25115184-3	2014	The absence or pharmacological blockade of mitochondrial Cx43 (mtCx43) reduces dye and potassium uptake.	Potassium	87-96	gap junction protein, alpha 1	Rattus norvegicus	57-61
24021239-0	2014	Role of Saccharomyces cerevisiae Trk1 in stabilization of intracellular potassium content upon changes in external potassium levels.	Potassium	115-124	Trk1p	Saccharomyces cerevisiae S288C	33-37
24021239-3	2014	By using yeasts lacking the Trk1,2 system or expressing different versions of the mutated main plasma membrane potassium transporter (Trk1), we show that Trk1 is not essential for adaptation to potassium changes but the dynamics of potassium loss is very different in the wild type and in trk1,2 mutant or in yeasts expressing Trk1 versions with highly impaired transport characteristics.	Potassium	111-120	Trk1p	Saccharomyces cerevisiae S288C	134-138
24021239-3	2014	By using yeasts lacking the Trk1,2 system or expressing different versions of the mutated main plasma membrane potassium transporter (Trk1), we show that Trk1 is not essential for adaptation to potassium changes but the dynamics of potassium loss is very different in the wild type and in trk1,2 mutant or in yeasts expressing Trk1 versions with highly impaired transport characteristics.	Potassium	111-120	Trk1p	Saccharomyces cerevisiae S288C	134-138
24021239-3	2014	By using yeasts lacking the Trk1,2 system or expressing different versions of the mutated main plasma membrane potassium transporter (Trk1), we show that Trk1 is not essential for adaptation to potassium changes but the dynamics of potassium loss is very different in the wild type and in trk1,2 mutant or in yeasts expressing Trk1 versions with highly impaired transport characteristics.	Potassium	111-120	Trk1p	Saccharomyces cerevisiae S288C	289-293
24021239-3	2014	By using yeasts lacking the Trk1,2 system or expressing different versions of the mutated main plasma membrane potassium transporter (Trk1), we show that Trk1 is not essential for adaptation to potassium changes but the dynamics of potassium loss is very different in the wild type and in trk1,2 mutant or in yeasts expressing Trk1 versions with highly impaired transport characteristics.	Potassium	111-120	Trk1p	Saccharomyces cerevisiae S288C	134-138
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 2	Homo sapiens	60-66
24882402-7	2014	Licorice-induced pseudoaldosteronism develops due to the inhibition of type 2 11beta-hydrosteroid dehydrogenase (11beta-HSD2) which results in the accumulation of cortisol in tubular epithelial cells that activate mineral corticoid receptors to stimulate the excretion of potassium that results in hypokalemia.	Potassium	272-281	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	113-124
25322648-2	2014	Preliminary administration of the ACE inhibitor enalapril (1 mg/kg, p.o., for 7 days) enhances the renal dopamine response with 3.5-fold increase in its diuretic effect and increases natriuresis 3.2 times and urine potassium excretion 5 times (p &lt; 0.05).	Potassium	215-224	angiotensin I converting enzyme	Rattus norvegicus	34-37
24267958-0	2014	Potassium uptake system Trk2 is crucial for yeast cell viability during anhydrobiosis.	Potassium	0-9	Trk2p	Saccharomyces cerevisiae S288C	24-28
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	152-161	Trk1p	Saccharomyces cerevisiae S288C	65-69
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	152-161	Trk2p	Saccharomyces cerevisiae S288C	74-78
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	152-161	Tok1p	Saccharomyces cerevisiae S288C	238-242
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	152-161	Nha1p	Saccharomyces cerevisiae S288C	287-291
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	209-218	Trk1p	Saccharomyces cerevisiae S288C	65-69
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 2	Homo sapiens	68-74
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 2	Homo sapiens	75-80
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 10	Homo sapiens	91-98
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 10	Homo sapiens	99-105
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	209-218	Trk2p	Saccharomyces cerevisiae S288C	74-78
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 4	Homo sapiens	119-125
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	209-218	Tok1p	Saccharomyces cerevisiae S288C	238-242
24267958-3	2014	In the model yeast Saccharomyces cerevisiae, two uptake systems, Trk1 and Trk2, are responsible for the accumulation of a relatively high intracellular potassium content (200-300 mM) and the efflux of surplus potassium is mediated by the Tok1 channel and active exporters Ena ATPase and Nha1 cation/proton antiporter.	Potassium	209-218	Nha1p	Saccharomyces cerevisiae S288C	287-291
24267958-6	2014	Mutants lacking the TRK2 gene accumulated significantly lower amounts of potassium ions in the stationary culture growth phase, and these lower amounts correlated with decreased resistance to dehydration/rehydration stress.	Potassium	73-82	Trk2p	Saccharomyces cerevisiae S288C	20-24
25366235-1	2014	At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium.	Potassium	41-50	potassium two pore domain channel subfamily K member 2	Homo sapiens	126-131
24267958-7	2014	Our results showed Trk2 to be the major potassium uptake system in stationary cells, and potassium content to be a crucial parameter for desiccation survival.	Potassium	40-49	Trk2p	Saccharomyces cerevisiae S288C	19-23
24354396-7	2013	Leptin-treated LA myocytes showed a larger sodium current, but a smaller ultra-rapid delayed rectifier potassium current, and sodium-calcium exchanger current than the control.	Potassium	103-112	leptin	Oryctolagus cuniculus	0-6
24220548-5	2014	The effect of the heptapeptide on potassium current was inhibited by a Mas receptor inhibitor (A779; 10(-8) M) as well as by a protein kinase A (PKA) inhibitor (10(-9) M) dialyzed into the cell.	Potassium	34-43	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	127-143
24220548-5	2014	The effect of the heptapeptide on potassium current was inhibited by a Mas receptor inhibitor (A779; 10(-8) M) as well as by a protein kinase A (PKA) inhibitor (10(-9) M) dialyzed into the cell.	Potassium	34-43	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	145-148
24220548-6	2014	Intracellular dialysis of the catalytic subunit of PKA (5 x 10(-8) M) enhanced the potassium current by 38% +- 3.4% (n = 14; P &lt; .05) but did not abolish the effect of Ang (1-7).	Potassium	83-92	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	51-54
24258619-3	2014	FXYD (FXYD domain-containing protein) 2, the gamma-subunit of NKA, is the first identified and the most abundant member of FXYD family, affecting the sodium/potassium affinity of NKA in the kidney.	Potassium	157-166	tachykinin precursor 1	Homo sapiens	62-65
24258619-3	2014	FXYD (FXYD domain-containing protein) 2, the gamma-subunit of NKA, is the first identified and the most abundant member of FXYD family, affecting the sodium/potassium affinity of NKA in the kidney.	Potassium	157-166	tachykinin precursor 1	Homo sapiens	179-182
24081156-4	2014	The astroglial current is composed of three components sensitive to neuronal activity, i.e. a long-lasting potassium current mediated by Kir4.1 channels, a transient glutamate transporter current and a slow residual current, partially mediated by GABA transporters and Kir4.1-independent potassium channels.	Potassium	107-116	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	137-143
24081156-7	2014	As Kir4.1 channel-mediated potassium uptake contributes to 80% of the synaptically evoked astroglial current, we investigated in turn its impact on short-term synaptic plasticity.	Potassium	27-36	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	3-9
24081156-8	2014	Using glial conditional Kir4.1 knockout mice, we found that astroglial potassium uptake reduces synaptic responses to repetitive stimulation and post-tetanic potentiation.	Potassium	71-80	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	24-30
24081156-9	2014	These results show that astrocytes integrate synaptic activity via multiple ionic channels and transporters and contribute to short-term plasticity in part via potassium clearance mediated by Kir4.1 channels.	Potassium	160-169	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	192-198
24268251-8	2014	The higher Ks value revealed that fast DET of GOx occurred at the electrode surface.	Potassium	11-13	hydroxyacid oxidase 1	Homo sapiens	46-49
25000676-2	2014	Ambulatory treatment with hypotensors, mainly angiotensin-renin system inhibitors, can be associated in these patients with potassium retention and risk of hyperkalemia.	Potassium	124-133	renin	Homo sapiens	58-63
25531090-0	2014	Genetic variants in renalase and blood pressure responses to dietary salt and potassium interventions: a family-based association study.	Potassium	78-87	renalase, FAD dependent amine oxidase	Homo sapiens	20-28
25531090-3	2014	The aim of this study was to examine the association between genetic variants in RNLS and blood pressure (BP) responses to strict dietary interventions of salt and potassium intake.	Potassium	164-173	renalase, FAD dependent amine oxidase	Homo sapiens	81-85
24310820-0	2014	The sodium chloride cotransporter SLC12A3: new roles in sodium, potassium, and blood pressure regulation.	Potassium	64-73	solute carrier family 12 member 3	Homo sapiens	34-41
24310820-5	2014	For example, the recent discoveries that NCC is activated by angiotensin II but inhibited by dietary potassium shed light on how the kidney handles sodium during hypovolemia (high angiotensin II) and hyperkalemia.	Potassium	101-110	angiotensinogen	Homo sapiens	180-194
25303187-5	2014	This study will investigate potassium intake and handling, and its impact on the cardiovascular health of a sample of normotensive Afro-Caribbeans by the possible modulation of the renin angiotensin aldosterone system (RAAS).	Potassium	28-37	renin	Homo sapiens	181-186
25303187-19	2014	This high potassium excretion could have been partly due to low plasma renin activity levels in the study participants.	Potassium	10-19	renin	Homo sapiens	71-76
24381583-9	2013	In mammals, Ka/Ks for BACE2 is higher than BACE1 but low ratios for both suggest purifying selection.	Potassium	15-17	beta-secretase 2	Homo sapiens	22-27
24358289-4	2013	The Ka/Ks ratio (&lt;1) and overall low level of nucleotide diversity in the FAE1 gene suggest that purifying selection is the major evolutionary force acting on this gene.	Potassium	7-9	ELOVL fatty acid elongase 5	Homo sapiens	77-81
24185037-1	2013	TGA results indicated that the maximum decomposition temperature of the biomass decreased from 373.9 to 359.0 C with increasing potassium concentration.	Potassium	128-137	T-box transcription factor 1	Homo sapiens	0-3
24151244-9	2013	The effect of KCNJ11 observed on muscle is potentially due to changes in activity of KATP channels, which in turn influence the flow of potassium in the intracellular space, allowing establishment of the membrane potential necessary for muscle contraction.	Potassium	136-145	potassium inwardly rectifying channel subfamily J member 11	Bos taurus	14-20
24514643-1	2013	Barium copper sulfur fluoride (BaCuSF) is a p-type transparent conductor (p-TC) that, when doped with potassium, exhibits exceptionally high conductivity.	Potassium	102-111	coagulation factor IX	Homo sapiens	44-78
24314077-2	2013	Design of I(KS)-targeting anti-arrhythmic drugs requires detailed three-dimensional structures of the KCNQ1/KCNE1 complex, a task made possible by Kv channel crystal structures (templates for KCNQ1 homology-modeling) and KCNE1 NMR structures.	Potassium	12-14	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	102-107
24314077-2	2013	Design of I(KS)-targeting anti-arrhythmic drugs requires detailed three-dimensional structures of the KCNQ1/KCNE1 complex, a task made possible by Kv channel crystal structures (templates for KCNQ1 homology-modeling) and KCNE1 NMR structures.	Potassium	12-14	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	108-113
24314077-2	2013	Design of I(KS)-targeting anti-arrhythmic drugs requires detailed three-dimensional structures of the KCNQ1/KCNE1 complex, a task made possible by Kv channel crystal structures (templates for KCNQ1 homology-modeling) and KCNE1 NMR structures.	Potassium	12-14	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	192-197
23684954-9	2013	These potentially powerful roles expand the influence of AQP4 and astrocytes beyond the original suggestions related to regulation of extracellular potassium and water balance.	Potassium	148-157	aquaporin 4	Mus musculus	57-61
23829355-1	2013	The G-protein-activated inwardly rectifying potassium channel Kir3.4 is expressed in the zona glomerulosa cell membrane and transports potassium out of the cell.	Potassium	44-53	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	62-68
23829355-4	2013	In 40-60% of aldosterone-producing adenomas there is a somatic mutation in the region of the KCNJ5 gene that codes for the selectivity filter that decreases potassium selectivity, allowing sodium to leak into the cells, thus depolarizing the membrane and initiating events that result in increased aldosterone synthesis.	Potassium	157-166	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	93-98
23760292-0	2013	Partial genetic deficiency in tissue kallikrein impairs adaptation to high potassium intake in humans.	Potassium	75-84	kallikrein 1	Homo sapiens	30-47
23760292-1	2013	Inactivation of the tissue kallikrein gene in mice impairs renal handling of potassium due to enhanced H, K-ATPase activity, and induces hyperkalemia.	Potassium	77-86	kallikrein 1	Homo sapiens	20-37
23760292-10	2013	Thus, impaired tissue kallikrein stimulation by a low-sodium/high-potassium diet in R53H subjects with partial tissue kallikrein deficiency highlights an inappropriate renal adaptation to potassium load, consistent with experimental data in mice.	Potassium	66-75	kallikrein 1	Homo sapiens	15-32
23760292-10	2013	Thus, impaired tissue kallikrein stimulation by a low-sodium/high-potassium diet in R53H subjects with partial tissue kallikrein deficiency highlights an inappropriate renal adaptation to potassium load, consistent with experimental data in mice.	Potassium	188-197	kallikrein 1	Homo sapiens	15-32
24052423-4	2013	Whereas the wild type and the  tok1 mutant cells exhibited similar depolarization curves, mutant cells lacking the two Trk1,2 potassium transporters revealed a significantly decreased membrane depolarization by K(+), particularly at lower extracellular potassium concentration [K(+)]out.	Potassium	126-135	Trk1p	Saccharomyces cerevisiae S288C	119-123
24190995-3	2013	Here we show that intracellular ATP activates heterologously coexpressed KCNQ1 and KCNE1 as well as I(Ks) in cardiac myocytes by directly binding to the C terminus of KCNQ1 to allow the pore to open.	Potassium	102-104	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	167-172
24233809-8	2013	Magnesium deficiency by interfering with ATPase functions causes increased intracellular calcium and sodium and decreases intracellular potassium concentration.	Potassium	136-145	dynein axonemal heavy chain 8	Homo sapiens	41-47
24180234-8	2013	CONCLUSIONS: AtPAP2 overexpression resulted in a widespread reprogramming of the transcriptome in the transgenic plants, which is characterized by changes in the carbon, nitrogen, potassium, and iron metabolism.	Potassium	180-189	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	13-19
24089192-8	2013	In contrast, IL-1beta secretion is ablated by potassium, scavenging mitochondrial ROS, and both cathepsin B and caspase-1 inhibition.	Potassium	46-55	interleukin 1 beta	Homo sapiens	13-21
24244710-4	2013	Urinalysis indicated pronounced changes in LRRK2 knockout rats in urine specific gravity, total volume, urine potassium, creatinine, sodium, and chloride that started as early as 1- to 2-months of age.	Potassium	110-119	leucine-rich repeat kinase 2	Rattus norvegicus	43-48
24180323-5	2013	The present study investigated estrogen-mediated modulation of two voltage-gated potassium channel (Kv) subunits, Kv4.2 and Kv4.3, that are expressed predominantly in PVN neurons and the functional current of Kv4.2 and Kv4.3, the transient outward potassium current (IA).	Potassium	81-90	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	114-119
24180323-5	2013	The present study investigated estrogen-mediated modulation of two voltage-gated potassium channel (Kv) subunits, Kv4.2 and Kv4.3, that are expressed predominantly in PVN neurons and the functional current of Kv4.2 and Kv4.3, the transient outward potassium current (IA).	Potassium	81-90	potassium voltage-gated channel subfamily D member 3	Rattus norvegicus	124-129
23744741-5	2013	As expected, the swelling rate, Ks , decreased when increasing the crosslink density from 78.6 to 14.7 min-1 over a range of 1-20 mol% PEGDA indicating that diffusivity into the matrix is dependent on crosslink density.	Potassium	32-34	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
24206565-8	2013	Potassium supplementation and sex hormone-based therapy may protect patients with LQT2.	Potassium	0-9	potassium voltage-gated channel subfamily H member 2	Homo sapiens	82-86
24133274-0	2013	Erg potassium currents of neonatal mouse Purkinje cells exhibit fast gating kinetics and are inhibited by mGluR1 activation.	Potassium	4-13	glutamate receptor, metabotropic 1	Mus musculus	106-112
24037327-0	2013	ATP-sensitive potassium currents from channels formed by Kir6 and a modified cardiac mitochondrial SUR2 variant.	Potassium	14-23	ATP binding cassette subfamily C member 9	Homo sapiens	99-103
24055606-0	2013	Compromised potassium recycling in the cochlea contributes to conservation of endocochlear potential in a mouse model of age-related hearing loss.	Potassium	12-21	cadherin 23 (otocadherin)	Mus musculus	121-145
24108112-12	2013	In patients with CD, Ks and lysis time were independently predicted by fibrinogen and C-reactive protein.	Potassium	21-23	fibrinogen beta chain	Homo sapiens	71-81
24108112-12	2013	In patients with CD, Ks and lysis time were independently predicted by fibrinogen and C-reactive protein.	Potassium	21-23	C-reactive protein	Homo sapiens	86-104
23500045-8	2013	The results unambiguously show that the CREM sequence folds into a G-quadruplex structure in the presence of a physiological concentration of potassium ions.	Potassium	142-151	cAMP responsive element modulator	Homo sapiens	40-44
24400161-11	2013	Studies in Xenopus oocytes revealed that both S219R and L220F had a deleterious effect on ROMK-mediated potassium currents.	Potassium	104-113	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	90-94
24012527-9	2013	It was determined that vindoline acted as a Kv2.1 inhibitor able to reduce the voltage-dependent outward potassium currents finally enhancing insulin secretion.	Potassium	105-114	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	44-49
24133274-0	2013	Erg potassium currents of neonatal mouse Purkinje cells exhibit fast gating kinetics and are inhibited by mGluR1 activation.	Potassium	4-13	ETS transcription factor	Mus musculus	0-3
24116006-2	2013	Two-pore domain (K2P) potassium channels are background channels which enable the leak of potassium ions from cells.	Potassium	22-31	keratin 76	Homo sapiens	17-20
24006450-4	2013	Coexpression of KCNQ1-S140G with KCNE1 generated potassium currents (S140G-IKs) that exhibited greater sensitivity to HMR-1556 than WT-IKs.	Potassium	49-58	potassium voltage-gated channel subfamily KQT member 1	Oryctolagus cuniculus	16-21
24006450-4	2013	Coexpression of KCNQ1-S140G with KCNE1 generated potassium currents (S140G-IKs) that exhibited greater sensitivity to HMR-1556 than WT-IKs.	Potassium	49-58	potassium voltage-gated channel subfamily E member 1	Oryctolagus cuniculus	33-38
23893870-4	2013	Here we show reciprocal action of SDF-1alpha and LPA, on potassium currents through Kir2.1 channels in primary murine microglia.	Potassium	57-66	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	84-90
24051376-1	2013	Inactivation of the B1 proton pump subunit (ATP6V1B1) in intercalated cells (ICs) leads to type I distal renal tubular acidosis (dRTA), a disease associated with salt- and potassium-losing nephropathy.	Potassium	172-181	ATPase, H+ transporting, lysosomal V1 subunit B1	Mus musculus	44-52
23893820-6	2013	Electrophysiological recordings in acute cortical slices showed that at P5 a proportion of layer 4 microglia transiently express voltage-dependant potassium currents of the delayed rectifier family, mostly mediated by Kv1.3 subunits, which are usually expressed by activated microglia under pathological conditions.	Potassium	147-156	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	218-223
23424208-9	2013	Our data indicated that the mechanism by which probucol inhibits I(Ks) was not mediated by the inhibition of cholesterol synthesis but depended on an interaction with the KCNQ1/KCNE1 complex.	Potassium	67-69	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	171-176
23424208-9	2013	Our data indicated that the mechanism by which probucol inhibits I(Ks) was not mediated by the inhibition of cholesterol synthesis but depended on an interaction with the KCNQ1/KCNE1 complex.	Potassium	67-69	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	177-182
23741043-9	2013	These findings suggest that VIP regulates the long-term firing rate of SCN neurons through a VIPR2-mediated increase in the cAMP pathway and implicate the fast delayed rectifier (FDR) potassium currents as one of the targets of this regulation.	Potassium	184-193	vasoactive intestinal polypeptide	Mus musculus	28-31
23878373-1	2013	The largest outward potassium current in the soma of neocortical pyramidal neurons is due to channels containing Kv2.1 alpha subunits.	Potassium	20-29	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	113-118
24137016-3	2013	Only recently has evidence accumulated to suggest that AQP4 is involved in such diverse functions as regulation of extracellular space volume, potassium buffering, cerebrospinal fluid circulation, interstitial fluid resorption, waste clearance, neuroinflammation, osmosensation, cell migration, and Ca(2+) signaling.	Potassium	143-152	aquaporin 4	Homo sapiens	55-59
24039773-8	2013	Pre-treatment of neutrophils with specific inhibitors of the myeloid-restricted class I phosphatidylinositol-3-OH kinase (PI(3)K) isoforms showed that the EGF-CM from Mod/Sev asthmatics depended on the gamma (p&lt;0.021) but not delta isoforms, while neutrophil survival required multiple class I PI(3)Ks.	Potassium	302-304	epidermal growth factor	Homo sapiens	155-158
23872451-9	2013	Adx+CSR rats also presented an increased function of 5-HT1A autoreceptors, since, in these rats, serotonin (1-10muM) produced a higher increase in the potassium dependent inward rectifying current in comparison with sham-operated animals.	Potassium	151-160	5-hydroxytryptamine receptor 1A	Rattus norvegicus	53-59
23963453-1	2013	MEKK2 (MAP/ERK kinase kinase-2) is a serine/threonine kinase that belongs to the MEKK/STE11 family of MAP kinase kinase kinases (MAP(3)Ks).	Potassium	135-137	mitogen-activated protein kinase kinase kinase 2	Homo sapiens	0-5
23963453-1	2013	MEKK2 (MAP/ERK kinase kinase-2) is a serine/threonine kinase that belongs to the MEKK/STE11 family of MAP kinase kinase kinases (MAP(3)Ks).	Potassium	135-137	mitogen-activated protein kinase kinase kinase 2	Homo sapiens	7-30
23963453-1	2013	MEKK2 (MAP/ERK kinase kinase-2) is a serine/threonine kinase that belongs to the MEKK/STE11 family of MAP kinase kinase kinases (MAP(3)Ks).	Potassium	135-137	mitogen-activated protein kinase kinase kinase 2	Homo sapiens	7-10
23963453-1	2013	MEKK2 (MAP/ERK kinase kinase-2) is a serine/threonine kinase that belongs to the MEKK/STE11 family of MAP kinase kinase kinases (MAP(3)Ks).	Potassium	135-137	mitogen-activated protein kinase kinase kinase 2	Homo sapiens	102-105
23988599-9	2013	Beta-2-adrenergic agonists and several other medications can affect serum potassium levels; although the potential risks posed by the use of such drugs in patients with a history of HPP are unclear, cautious use in the context of known HPP is advised.	Potassium	74-83	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	0-6
23893410-0	2013	Trypanosome Letm1 protein is essential for mitochondrial potassium homeostasis.	Potassium	57-66	leucine zipper and EF-hand containing transmembrane protein 1	Homo sapiens	12-17
23893410-3	2013	Studies almost exclusively performed in opisthokonts have attributed several roles to Letm1, including maintaining mitochondrial morphology, mediating either calcium or potassium/proton antiport, and facilitating mitochondrial translation.	Potassium	169-178	leucine zipper and EF-hand containing transmembrane protein 1	Homo sapiens	86-91
23893410-5	2013	We demonstrate that Letm1 is involved in maintaining mitochondrial volume via potassium/proton exchange across the inner membrane.	Potassium	78-87	leucine zipper and EF-hand containing transmembrane protein 1	Homo sapiens	20-25
23735420-5	2013	The antihypertensive effect of potassium supplementation appears to occur through several mechanisms that include regulation of vascular sensitivity to catecholamines, promotion of natriuresis, limiting plasma renin activity, and improving endothelial function.	Potassium	31-40	renin	Homo sapiens	210-215
23821668-5	2013	This site resembles structurally and functionally the potassium sites in the human FEN1 and exonuclease 1 enzymes.	Potassium	54-63	flap structure-specific endonuclease 1	Homo sapiens	83-87
23859824-7	2013	In the case of CGNs deprived of depolarizing potassium (5K apoptotic condition), caspases appear to play a dominant role in CtBP downregulation.	Potassium	45-54	poly(rC) binding protein 2	Mus musculus	124-128
23821668-5	2013	This site resembles structurally and functionally the potassium sites in the human FEN1 and exonuclease 1 enzymes.	Potassium	54-63	exonuclease 1	Homo sapiens	92-105
23792826-11	2013	The accumulation of the KS dehydrin was also responsive to exogenous ABA.	Potassium	24-26	dehydrin	Glycine max	27-35
23878078-2	2013	In this work, we provide evidence that AtHDA7, a HISTONE DEACETYLASE (HDAC) of the Reduced Potassium Dependency3 (RPD3) superfamily, is crucial for female gametophyte development and embryogenesis in Arabidopsis (Arabidopsis thaliana).	Potassium	91-100	histone deacetylase7	Arabidopsis thaliana	39-45
23878078-2	2013	In this work, we provide evidence that AtHDA7, a HISTONE DEACETYLASE (HDAC) of the Reduced Potassium Dependency3 (RPD3) superfamily, is crucial for female gametophyte development and embryogenesis in Arabidopsis (Arabidopsis thaliana).	Potassium	91-100	histone deacetylase	Arabidopsis thaliana	49-68
23868291-4	2013	Homologous PNA readily invades a quadruplex derived from the promoter regulatory region found upstream of the MYC proto-oncogene to form a heteroquadruplex at high potassium concentration mimicking the intracellular environment, whereas complementary PNA exhibits virtually no hybridization.	Potassium	164-173	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	110-113
23878078-2	2013	In this work, we provide evidence that AtHDA7, a HISTONE DEACETYLASE (HDAC) of the Reduced Potassium Dependency3 (RPD3) superfamily, is crucial for female gametophyte development and embryogenesis in Arabidopsis (Arabidopsis thaliana).	Potassium	91-100	histone deacetylase	Arabidopsis thaliana	70-74
23483653-2	2013	The additional role of PTS(Ntr) as a regulatory link between nitrogen and carbon utilization in Escherichia coli is assumed to be closely related to molecular functions of IIA(Ntr) in potassium homeostasis.	Potassium	184-193	colicin Ia immunity protein	Escherichia coli	172-175
23835093-6	2013	V1a agonist (Phe(2)-Ile(3)-Orn(8)-vasopressin) reproduced the renal effects of dAVT on sodium and potassium excretion but not on water reabsorption.	Potassium	98-107	arginine vasopressin	Rattus norvegicus	34-45
23977150-0	2013	Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.	Potassium	47-56	potassium voltage-gated channel, subfamily Q, member 2	Mus musculus	11-16
23711155-0	2013	Human Drg1 is a potassium-dependent GTPase enhanced by Lerepo4.	Potassium	16-25	developmentally regulated GTP binding protein 1	Homo sapiens	6-10
23515479-3	2013	The potassium atoms in ZBP-K are located near 8MR windows in the 2D zigzag channels, and the potassium cations are successfully exchanged with ammonium cations retaining the open-framework structure.	Potassium	4-13	zona pellucida glycoprotein 4	Homo sapiens	23-26
23515479-3	2013	The potassium atoms in ZBP-K are located near 8MR windows in the 2D zigzag channels, and the potassium cations are successfully exchanged with ammonium cations retaining the open-framework structure.	Potassium	93-102	zona pellucida glycoprotein 4	Homo sapiens	23-26
23711155-0	2013	Human Drg1 is a potassium-dependent GTPase enhanced by Lerepo4.	Potassium	16-25	zinc finger CCCH-type containing 15	Homo sapiens	55-62
25157205-4	2013	Recent studies in our laboratory indicate that brain aromatase activity is rapidly inhibited by an increase in intracellular calcium concentration resulting from potassium-induced depolarization or from the activation of glutamatergic receptors.	Potassium	162-171	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	53-62
23753405-1	2013	The renal outer medullary potassium channel (ROMK, KCNJ1) mediates potassium recycling and facilitates sodium reabsorption through the Na(+)/K(+)/2Cl(-) cotransporter in the loop of Henle and potassium secretion at the cortical collecting duct.	Potassium	26-35	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	45-49
23753405-1	2013	The renal outer medullary potassium channel (ROMK, KCNJ1) mediates potassium recycling and facilitates sodium reabsorption through the Na(+)/K(+)/2Cl(-) cotransporter in the loop of Henle and potassium secretion at the cortical collecting duct.	Potassium	26-35	potassium inwardly-rectifying channel, subfamily J, member 1	Rattus norvegicus	51-56
23753405-1	2013	The renal outer medullary potassium channel (ROMK, KCNJ1) mediates potassium recycling and facilitates sodium reabsorption through the Na(+)/K(+)/2Cl(-) cotransporter in the loop of Henle and potassium secretion at the cortical collecting duct.	Potassium	67-76	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	45-49
23753405-1	2013	The renal outer medullary potassium channel (ROMK, KCNJ1) mediates potassium recycling and facilitates sodium reabsorption through the Na(+)/K(+)/2Cl(-) cotransporter in the loop of Henle and potassium secretion at the cortical collecting duct.	Potassium	67-76	potassium inwardly-rectifying channel, subfamily J, member 1	Rattus norvegicus	51-56
23849528-10	2013	Regular insulin therapy may be more effective than infrequent large bolus therapy for potassium homeostasis.	Potassium	86-95	insulin	Homo sapiens	8-15
23902721-10	2013	CONCLUSIONS: In this patient, CUL3 was found to play a fundamental role in the regulation of blood pressure, potassium levels, and acid-base balance.	Potassium	109-118	cullin 3	Homo sapiens	30-34
23777398-1	2013	Measurements of aroxyl radical (ArO( ))-scavenging rate constants (ks(AOH)) of antioxidants (AOHs) (alpha-tocopherol (alpha-TocH), ubiquinol-10 (UQ10H2), and sodium ascorbate (Na(+)AsH(-))) were performed in 2-propanol/water (2-PrOH/H2O, 5/1, v/v) solution using stopped-flow spectrophotometry.	Potassium	67-69	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	32-35
23774812-7	2013	Mineralocorticoid-receptor antagonists are associated with decreased mortality in patients with heart disease and show promise in patients with kidney injury, but can elevate serum potassium concentration.	Potassium	181-190	nuclear receptor subfamily 3 group C member 2	Homo sapiens	0-26
23792956-4	2013	Our recent data indicate that hERG channels undergo enhanced endocytic degradation under low potassium (hypokalemia) conditions.	Potassium	93-102	ETS transcription factor ERG	Homo sapiens	30-34
23678030-0	2013	Role of vasopressin in maintenance of potassium homeostasis in severe hemorrhage.	Potassium	38-47	vasopressin	Sus scrofa	8-19
23678030-4	2013	While it has been demonstrated for some time that vasopressin can influence secretion of potassium in the distal nephron, the magnitude of this effect and conditions under which this contributes to physiological modulation of potassium excretion has yet to be defined.	Potassium	89-98	vasopressin	Sus scrofa	50-61
23678030-5	2013	In this review, we assess the evidence that would suggest that vasopressin plays a key role in modulating potassium excretion and is important in the regulation of potassium homeostasis during hemorrhage.	Potassium	106-115	vasopressin	Sus scrofa	63-74
23678030-5	2013	In this review, we assess the evidence that would suggest that vasopressin plays a key role in modulating potassium excretion and is important in the regulation of potassium homeostasis during hemorrhage.	Potassium	164-173	vasopressin	Sus scrofa	63-74
23815537-0	2013	Salt loading and potassium supplementation: effects on ambulatory arterial stiffness index and endothelin-1 levels in normotensive and mild hypertensive patients.	Potassium	17-26	endothelin 1	Homo sapiens	95-107
23604714-3	2013	The isometric contractions in the isolated second-order branch of mesenteric artery helical strips from CPI-17-Tg mice were significantly enhanced compared with controls in response to phenylephrine, U-46619, serotonin, ANG II, high potassium, and calcium.	Potassium	233-242	protein phosphatase 1, regulatory inhibitor subunit 14A	Mus musculus	104-110
23586466-6	2013	However, only potassium currents recorded in HEK 293 cells over-expressing both hSloalpha and hSlobeta1 were activated by oestrone, oestrone oxime and Quat DME-oestradiol.	Potassium	14-23	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	80-103
23807092-2	2013	K(2P)3.1 and K(2P)9.1 leak potassium from the cell at rest and directly impact membrane potential.	Potassium	27-36	potassium two pore domain channel subfamily K member 3	Homo sapiens	0-8
23807092-2	2013	K(2P)3.1 and K(2P)9.1 leak potassium from the cell at rest and directly impact membrane potential.	Potassium	27-36	potassium two pore domain channel subfamily K member 9	Homo sapiens	13-21
23898345-7	2013	Normalization of the serum potassium level and disappearance of proteinuria were established with an ACE inhibitor and potassium supplementation.	Potassium	27-36	angiotensin I converting enzyme	Homo sapiens	101-104
23861848-9	2013	Shortly after terminal ischemia/anoxia induction, the onset of a steep rise in the extracellular potassium concentration and an increase in lambda was faster in alpha-syn -/- mice, but the final values did not differ between alpha-syn -/- and alpha-syn +/+ mice.	Potassium	97-106	synuclein, alpha	Mus musculus	161-170
23753530-8	2013	Ucn2 cotherapy additionally increased urine potassium and creatinine excretion.	Potassium	44-53	urocortin-2	Ovis aries	0-4
23753530-9	2013	In contrast to the rise in plasma potassium induced by CA, Ucn2 cotreatment reduced potassium concentrations.	Potassium	84-93	urocortin-2	Ovis aries	59-63
23753530-11	2013	Importantly, Ucn2 prevented CA-induced rises in plasma potassium.	Potassium	55-64	urocortin-2	Ovis aries	13-17
23815537-7	2013	High-salt intervention significantly increased BP, AASI, s-AASI (all P&lt;.001); potassium supplementation reversed increased plasma ET-1 levels.	Potassium	81-90	endothelin 1	Homo sapiens	133-137
23815537-9	2013	Potassium supplementation decreased systolic BP and ET-1 to a significantly greater extent in salt-sensitive vs non-salt-sensitive individuals (P&lt;.001).	Potassium	0-9	endothelin 1	Homo sapiens	52-56
23815537-10	2013	Significant correlations were identified between s-AASI and ET-1 change ratios in response to both high-salt intervention and potassium supplementation (P&lt;.001).	Potassium	126-135	endothelin 1	Homo sapiens	60-64
23552867-4	2013	Potassium treatment increased the synthesis and excretion of tissue kallikrein (Klk1/rKLK1) accompanied by a significant reduction in blood pressure and renal fibrosis and with downregulation of renal transforming growth factor-beta (TGF-beta) mRNA and protein compared with rats that did not receive potassium.	Potassium	0-9	kallikrein 1	Rattus norvegicus	80-84
23853500-5	2013	Herein we present a 42-yr-old Korean male of DM1 with abnormally elevated serum sodium and potassium.	Potassium	91-100	DM1 protein kinase	Homo sapiens	45-48
23552867-4	2013	Potassium treatment increased the synthesis and excretion of tissue kallikrein (Klk1/rKLK1) accompanied by a significant reduction in blood pressure and renal fibrosis and with downregulation of renal transforming growth factor-beta (TGF-beta) mRNA and protein compared with rats that did not receive potassium.	Potassium	0-9	kallikrein 1	Rattus norvegicus	85-90
23552867-4	2013	Potassium treatment increased the synthesis and excretion of tissue kallikrein (Klk1/rKLK1) accompanied by a significant reduction in blood pressure and renal fibrosis and with downregulation of renal transforming growth factor-beta (TGF-beta) mRNA and protein compared with rats that did not receive potassium.	Potassium	301-310	kallikrein 1	Rattus norvegicus	80-84
23760924-0	2013	Connexin 43 impacts on mitochondrial potassium uptake.	Potassium	37-46	gap junction protein, alpha 1	Mus musculus	0-11
23760924-13	2013	The ablation of Cx43 (n = 5) reduced the velocity of the potassium influx from 100 +- 11.2% in control mitochondria (n = 9) to 66.6 +- 5.5% (p &lt; 0.05).	Potassium	57-66	gap junction protein, alpha 1	Mus musculus	16-20
23760924-14	2013	Taken together, our data indicate that both pharmacological inhibition and genetic ablation of Cx43 reduce mitochondrial potassium influx.	Potassium	121-130	gap junction protein, alpha 1	Mus musculus	95-99
23400760-2	2013	Mutations in the pore forming subunit KV4.3 leading to an increase in the transient outward potassium current (Ito) have previously been associated with the Brugada Syndrome.	Potassium	92-101	potassium voltage-gated channel subfamily D member 3	Homo sapiens	38-43
23548411-7	2013	Moreover, renin-angiotensin system-blocking drugs may be harmful in such patients because they can functionally interfere with the effects of reactive rises in PRA that are triggered to prevent potentially dangerous falls in blood pressure, increases in plasma potassium, and falls in glomerular filtration rate.	Potassium	261-270	renin	Homo sapiens	10-15
23755094-16	2014	The dislocation of Kir4.1 will disturb the retinal potassium and water homeostasis, and osmotic generation of free radicals and inflammatory lipids may contribute to neurovascular injury.	Potassium	51-60	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	19-25
23400760-10	2013	This association of KV4.3 gain-of-function and early-onset lone AF further supports the hypothesis that increased potassium current enhances AF susceptibility.	Potassium	114-123	potassium voltage-gated channel subfamily D member 3	Homo sapiens	20-25
23699522-0	2013	Protection from noise-induced hearing loss by Kv2.2 potassium currents in the central medial olivocochlear system.	Potassium	52-61	potassium voltage gated channel, Shab-related subfamily, member 2	Mus musculus	46-51
23734178-6	2013	E633 is conserved among class I PI3 Ks, and its mutation in p110beta is also activating.	Potassium	36-38	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	60-68
23720627-1	2013	Two-pore domain K(+) (KCNK, K2P) channels underlie the "leak" (background) potassium conductance in many types of excitable cells.	Potassium	75-84	keratin 76	Homo sapiens	28-31
23734226-9	2013	aegypti) is exacerbated when hemolymph potassium levels are elevated, suggesting that Kir channels are essential for maintenance of whole-animal potassium homeostasis.	Potassium	39-48	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	86-89
23734226-9	2013	aegypti) is exacerbated when hemolymph potassium levels are elevated, suggesting that Kir channels are essential for maintenance of whole-animal potassium homeostasis.	Potassium	145-154	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	86-89
23730307-2	2013	Recently, the Kruppel-like factor 15 (Klf15) was found to transcriptionally control rhythmic expression of KChIP2, a critical subunit required for generating the transient outward potassium current (Ito), and that deficiency or excess of Klf15 increased the susceptibility of arrhythmias.	Potassium	180-189	Kruppel like factor 15	Homo sapiens	14-36
23730307-2	2013	Recently, the Kruppel-like factor 15 (Klf15) was found to transcriptionally control rhythmic expression of KChIP2, a critical subunit required for generating the transient outward potassium current (Ito), and that deficiency or excess of Klf15 increased the susceptibility of arrhythmias.	Potassium	180-189	Kruppel like factor 15	Homo sapiens	38-43
23730307-2	2013	Recently, the Kruppel-like factor 15 (Klf15) was found to transcriptionally control rhythmic expression of KChIP2, a critical subunit required for generating the transient outward potassium current (Ito), and that deficiency or excess of Klf15 increased the susceptibility of arrhythmias.	Potassium	180-189	potassium voltage-gated channel interacting protein 2	Homo sapiens	107-113
27122708-1	2013	UNLABELLED: It is well-known that aldosterone plays an important role in reabsorption of sodium and fluid, and in potassium excretion in kidneys via epithelial mineralocorticoid receptor (MR) activation.	Potassium	114-123	nuclear receptor subfamily 3 group C member 2	Homo sapiens	160-186
23530046-10	2013	Acidic medium triggered pH-dependent secretion of IL-1beta and activation of caspase-1 via a mechanism involving potassium efflux from the cells.	Potassium	113-122	interleukin 1 beta	Homo sapiens	50-58
23530046-10	2013	Acidic medium triggered pH-dependent secretion of IL-1beta and activation of caspase-1 via a mechanism involving potassium efflux from the cells.	Potassium	113-122	caspase 1	Homo sapiens	77-86
27122708-1	2013	UNLABELLED: It is well-known that aldosterone plays an important role in reabsorption of sodium and fluid, and in potassium excretion in kidneys via epithelial mineralocorticoid receptor (MR) activation.	Potassium	114-123	nuclear receptor subfamily 3 group C member 2	Homo sapiens	188-190
23633076-4	2013	We compared the ratio of the rate of nonsynonymous (Ka) and synonymous (Ks) substitutions (Ka/Ks ratio) in the mitochondrial protein-coding gene sequences and found that atp8 had the highest Ka/Ks ratios in comparisons of A. franciscana with either A. tibetiana or A. urmiana and that atp6 had the highest Ka/Ks ratio between A. tibetiana and A. urmiana.	Potassium	72-74	ATP synthase F0 subunit 8	Artemia franciscana	170-174
23538141-0	2013	Intracellular angiotensin II increases the total potassium current and the resting potential of arterial myocytes from vascular resistance vessels of the rat.	Potassium	49-58	angiotensinogen	Rattus norvegicus	14-28
23538141-2	2013	The influence of intracellular and extracellular administration of angiotensin II (Ang II; 10(-9) M) on total potassium current of arterial myocytes isolated from mesenteric arteries of Sprague Dawley rats was investigated.	Potassium	110-119	angiotensinogen	Rattus norvegicus	67-81
23538141-2	2013	The influence of intracellular and extracellular administration of angiotensin II (Ang II; 10(-9) M) on total potassium current of arterial myocytes isolated from mesenteric arteries of Sprague Dawley rats was investigated.	Potassium	110-119	angiotensinogen	Rattus norvegicus	83-89
23538141-5	2013	The presence of endogenous or internalized intracellular Ang II in vascular resistance vessels and its effect on potassium current and resting potential indicates that the peptide present inside the arterial myocytes plays an important role on the regulation of vascular tone and consequently on peripheral resistance, which is a determining factor in the regulation of arterial blood pressure.	Potassium	113-122	angiotensinogen	Rattus norvegicus	57-63
23532834-3	2013	The subject of this study was a search for vasopressin and vasotocin analogues with selective effects on renal water, sodium and potassium excretion.	Potassium	129-138	arginine vasopressin	Rattus norvegicus	43-54
23250862-0	2013	Potassium depolarization and raised calcium induces alpha-synuclein aggregates.	Potassium	0-9	synuclein alpha	Homo sapiens	52-67
23250862-3	2013	We hypothesized that depolarization with potassium resulting in raised Ca(2+) in a PD cell culture model will lead to the formation of alpha-synuclein protein aggregates and that the intracellular Ca(2+) buffer, BAPTA-AM, may suppress their formation.	Potassium	41-50	synuclein alpha	Homo sapiens	135-150
23427307-9	2013	The amplitude of the slow, inward astrocytic current due to potassium (K(+)) influx was also enhanced following activation of the endogenous mGluRs or the astrocyte-specific MrgA1 Gq GPCRs.	Potassium	60-69	MAS-related GPR, member A1	Mus musculus	174-179
23633076-4	2013	We compared the ratio of the rate of nonsynonymous (Ka) and synonymous (Ks) substitutions (Ka/Ks ratio) in the mitochondrial protein-coding gene sequences and found that atp8 had the highest Ka/Ks ratios in comparisons of A. franciscana with either A. tibetiana or A. urmiana and that atp6 had the highest Ka/Ks ratio between A. tibetiana and A. urmiana.	Potassium	94-96	ATP synthase F0 subunit 8	Artemia franciscana	170-174
23633076-4	2013	We compared the ratio of the rate of nonsynonymous (Ka) and synonymous (Ks) substitutions (Ka/Ks ratio) in the mitochondrial protein-coding gene sequences and found that atp8 had the highest Ka/Ks ratios in comparisons of A. franciscana with either A. tibetiana or A. urmiana and that atp6 had the highest Ka/Ks ratio between A. tibetiana and A. urmiana.	Potassium	94-96	ATP synthase F0 subunit 8	Artemia franciscana	170-174
23633076-4	2013	We compared the ratio of the rate of nonsynonymous (Ka) and synonymous (Ks) substitutions (Ka/Ks ratio) in the mitochondrial protein-coding gene sequences and found that atp8 had the highest Ka/Ks ratios in comparisons of A. franciscana with either A. tibetiana or A. urmiana and that atp6 had the highest Ka/Ks ratio between A. tibetiana and A. urmiana.	Potassium	94-96	ATP synthase F0 subunit 8	Artemia franciscana	170-174
23593319-4	2013	Heterologous expression and co-immunoprecipitation shows that DPP6 co-expression with TASK-3 results in the formation of a protein complex that enhances resting membrane potassium conductance.	Potassium	170-179	dipeptidyl peptidase like 6	Homo sapiens	62-66
23596459-5	2013	The p.P574S KV7.3 variant significantly reduced potassium current amplitude in Xenopus laevis oocytes when co-expressed with KV7.5 but not with KV7.2 or KV7.4.	Potassium	48-57	potassium voltage-gated channel subfamily Q member 3 L homeolog	Xenopus laevis	12-17
23596459-5	2013	The p.P574S KV7.3 variant significantly reduced potassium current amplitude in Xenopus laevis oocytes when co-expressed with KV7.5 but not with KV7.2 or KV7.4.	Potassium	48-57	potassium voltage-gated channel subfamily Q member 5	Homo sapiens	125-130
23550140-5	2013	This gene encodes a transporter required for high-affinity potassium transport in S. cerevisiae Data from reciprocal hemizygosity experiments with TRK1 deletion strains in K12 and BY backgrounds, as well as analysis of the deletion of this gene in the K12 strain, demonstrate that the K12 allele of TRK1 is responsible for ammonium toxicity resistance.	Potassium	59-68	Trk1p	Saccharomyces cerevisiae S288C	299-303
23550140-7	2013	These results demonstrate that the gene encoded by the K12 allele of TRK1 has a greater affinity for potassium than the standard allele of TRK1 found in Saccharomyces strains.	Potassium	101-110	Trk1p	Saccharomyces cerevisiae S288C	69-73
23123559-9	2013	Patients in cardiac arrest should receive uninterrupted CPR; with asystole, CPR may be terminated (or withheld) if a patient is lethally injured or completely frozen, the airway is blocked and duration of burial &gt;35 min, serum potassium &gt;12 mmol L(-1), risk to the rescuers is unacceptably high or a valid do-not-resuscitate order exists.	Potassium	230-239	cytochrome p450 oxidoreductase	Homo sapiens	76-79
23426971-0	2013	Interleukin-10 inhibits angiotensin II-induced decrease in neuronal potassium current.	Potassium	68-77	interleukin 10	Rattus norvegicus	0-14
23426971-0	2013	Interleukin-10 inhibits angiotensin II-induced decrease in neuronal potassium current.	Potassium	68-77	angiotensinogen	Rattus norvegicus	24-38
23298862-8	2013	For methadone individual enantiomers and metabolism by CYP2B6.6 compared with CYP2B6.1, Vmax was diminished, Ks was greater and the in vitro intrinsic clearance was diminished 5- to 6-fold.	Potassium	109-111	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	55-61
23430254-0	2013	Renal proteinase-activated receptor 2, a new actor in the control of blood pressure and plasma potassium level.	Potassium	95-104	F2R like trypsin receptor 1	Homo sapiens	6-37
23430254-7	2013	Conversely to angiotensin 2 receptor, PAR2 is involved in the regulation of sodium and potassium balance in the context of either stimulation or nonstimulation of the renin/angiotensin/aldosterone system.	Potassium	87-96	F2R like trypsin receptor 1	Homo sapiens	38-42
23360744-6	2013	In this article, we provide a comprehensive overview of the genetic, cell biological, and pathophysiological causes of NDI, with emphasis on the congenital forms and the acquired forms arising from lithium and other drug therapies, acute and chronic renal failure, and disturbed levels of calcium and potassium.	Potassium	301-310	arginine vasopressin receptor 2	Homo sapiens	119-122
23561701-1	2013	Na(+)/K(+)-ATPase alpha 2 (Atp1a2) is an integral plasma membrane protein belonging to the P-type ATPase family that is responsible for maintaining the sodium (Na(+)) and potassium (K(+)) gradients across cellular membranes with hydrolysis of ATP.	Potassium	171-180	ATPase, Na+/K+ transporting, alpha 2 polypeptide	Mus musculus	27-33
23298862-8	2013	For methadone individual enantiomers and metabolism by CYP2B6.6 compared with CYP2B6.1, Vmax was diminished, Ks was greater and the in vitro intrinsic clearance was diminished 5- to 6-fold.	Potassium	109-111	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	78-84
23454581-0	2013	Molecular analysis of a conditional hal3 vhs3 yeast mutant links potassium homeostasis with flocculation and invasiveness.	Potassium	65-74	phosphopantothenoylcysteine decarboxylase complex subunit SIS2	Saccharomyces cerevisiae S288C	36-40
23454581-0	2013	Molecular analysis of a conditional hal3 vhs3 yeast mutant links potassium homeostasis with flocculation and invasiveness.	Potassium	65-74	phosphopantothenoylcysteine decarboxylase complex subunit VHS3	Saccharomyces cerevisiae S288C	41-45
23454581-5	2013	The evidence indicates that hyperactivation of Ppz1 would impair potassium transport through the Trk1/Trk2 transporters, thus resulting in a decrease in the intracellular pH and a subsequent increase in the levels of cAMP.	Potassium	65-74	salt homeostasis regulator	Saccharomyces cerevisiae S288C	47-51
22921586-6	2013	Additionally, efflux of intracellular potassium, lysosomal rupture, and oxygen radical (ROS) production are crucial for caspase-1 processing and IL-1beta secretion by TDB.	Potassium	38-47	caspase 1	Mus musculus	120-129
22921586-6	2013	Additionally, efflux of intracellular potassium, lysosomal rupture, and oxygen radical (ROS) production are crucial for caspase-1 processing and IL-1beta secretion by TDB.	Potassium	38-47	interleukin 1 beta	Mus musculus	145-153
23454581-8	2013	Cells lacking Trk1,2 display an invasive phenotype that is abolished by deletion of FLO8 or by increasing the potassium concentration in the medium.	Potassium	110-119	Trk1p	Saccharomyces cerevisiae S288C	14-18
23454581-5	2013	The evidence indicates that hyperactivation of Ppz1 would impair potassium transport through the Trk1/Trk2 transporters, thus resulting in a decrease in the intracellular pH and a subsequent increase in the levels of cAMP.	Potassium	65-74	Trk1p	Saccharomyces cerevisiae S288C	97-101
23454581-5	2013	The evidence indicates that hyperactivation of Ppz1 would impair potassium transport through the Trk1/Trk2 transporters, thus resulting in a decrease in the intracellular pH and a subsequent increase in the levels of cAMP.	Potassium	65-74	Trk2p	Saccharomyces cerevisiae S288C	102-106
23443813-8	2013	In APA, CYP11B2 score adjusted for tumor volume was positively correlated with plasma aldosterone and negatively correlated with serum potassium.	Potassium	135-144	glutamyl aminopeptidase	Homo sapiens	3-6
23443813-8	2013	In APA, CYP11B2 score adjusted for tumor volume was positively correlated with plasma aldosterone and negatively correlated with serum potassium.	Potassium	135-144	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	8-15
23548744-3	2013	In this study, we found that the REDUCED POTASSIUM DEPENDENCY3/HISTONE DEACETYLASE1-type histone deacetylase HDA15 directly interacted with PIF3 in vivo and in vitro.	Potassium	41-50	histone deacetylase 1	Arabidopsis thaliana	63-83
23232841-0	2013	An increased TREK-1-like potassium current in ventricular myocytes during rat cardiac hypertrophy.	Potassium	25-34	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	13-19
23232841-11	2013	TREK-1 might balance potassium ion flow during hypertrophy and might be a potential drug target for heart protection.	Potassium	21-30	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	0-6
23376036-0	2013	Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle.	Potassium	76-85	Rap guanine nucleotide exchange factor 3	Rattus norvegicus	0-4
23373701-4	2013	Moreover, the D2R inhibitor raclopride blocked the increase of both GDNF and Zif268 expression following potassium-evoked dopamine release in SH-SY5Y cells.	Potassium	105-114	glial cell derived neurotrophic factor	Homo sapiens	68-72
23373701-4	2013	Moreover, the D2R inhibitor raclopride blocked the increase of both GDNF and Zif268 expression following potassium-evoked dopamine release in SH-SY5Y cells.	Potassium	105-114	early growth response 1	Homo sapiens	77-83
23548744-3	2013	In this study, we found that the REDUCED POTASSIUM DEPENDENCY3/HISTONE DEACETYLASE1-type histone deacetylase HDA15 directly interacted with PIF3 in vivo and in vitro.	Potassium	41-50	histone deacetylase 15	Arabidopsis thaliana	109-114
23548744-3	2013	In this study, we found that the REDUCED POTASSIUM DEPENDENCY3/HISTONE DEACETYLASE1-type histone deacetylase HDA15 directly interacted with PIF3 in vivo and in vitro.	Potassium	41-50	phytochrome interacting factor 3	Arabidopsis thaliana	140-144
23324064-1	2013	INTRODUCTION: Over the last two decades, the known functions of the mineralocorticoid receptor (MR) have expanded beyond regulation of sodium and potassium in epithelial cells to encompass physiological and pathophysiological effects in many tissues throughout the body.	Potassium	146-155	nuclear receptor subfamily 3, group C, member 2	Mus musculus	68-94
23416519-5	2013	Functional in vitro studies of ATP1A1 mutants showed loss of pump activity and strongly reduced affinity for potassium.	Potassium	109-118	ATPase Na+/K+ transporting subunit alpha 1	Homo sapiens	31-37
23324064-1	2013	INTRODUCTION: Over the last two decades, the known functions of the mineralocorticoid receptor (MR) have expanded beyond regulation of sodium and potassium in epithelial cells to encompass physiological and pathophysiological effects in many tissues throughout the body.	Potassium	146-155	nuclear receptor subfamily 3, group C, member 2	Mus musculus	96-98
23531840-0	2013	5-HT1A receptor-mediated activation of outward potassium current by serotonin in mouse cultured spiral ganglion neurons.	Potassium	47-56	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	0-15
23531840-7	2013	These results suggest that serotonin increases outward potassium currents in cultured spiral ganglion neurons through the activation of 5-HT1A receptor.	Potassium	55-64	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	136-151
23255725-10	2013	Hypocretin excited MCH cells by activating a sodium-calcium exchanger and by reducing potassium currents; NPY reduced activity by increasing an inwardly rectifying potassium current.	Potassium	86-95	hypocretin	Mus musculus	0-10
23171954-2	2013	MR antagonists are considered to be potassium-sparing diuretics that exert their effect by blocking MR in the kidney, and they are not the first choice for treating hypertension.	Potassium	36-45	nuclear receptor subfamily 3 group C member 2	Homo sapiens	0-2
23610573-1	2013	OBJECTIVES: To investigate the effect of nerve growth factor (NGF) on the action potential and potassium currents of non-infarcted myocardium in the myocardial infarcted rabbit model.	Potassium	95-104	beta-nerve growth factor	Oryctolagus cuniculus	41-60
23610573-1	2013	OBJECTIVES: To investigate the effect of nerve growth factor (NGF) on the action potential and potassium currents of non-infarcted myocardium in the myocardial infarcted rabbit model.	Potassium	95-104	beta-nerve growth factor	Oryctolagus cuniculus	62-65
23610573-7	2013	CONCLUSIONS: Our results suggest that NGF treatment significantly prolongs APD in HMI cardiomyocytes and that a decrease in outward potassium currents and an increase of inward Ca(2+) current are likely the underlying mechanism of action.	Potassium	132-141	beta-nerve growth factor	Oryctolagus cuniculus	38-41
23255725-10	2013	Hypocretin excited MCH cells by activating a sodium-calcium exchanger and by reducing potassium currents; NPY reduced activity by increasing an inwardly rectifying potassium current.	Potassium	164-173	neuropeptide Y	Mus musculus	106-109
23274715-9	2013	The results suggest that MWCNT increases the excitability of hippocampal CA1 neurons by inhibiting voltage-gated potassium current.	Potassium	113-122	carbonic anhydrase 1	Rattus norvegicus	73-76
23241319-1	2013	KCNQ1 and hERG encode the voltage-gated potassium channel alpha-subunits of the cardiac repolarizing currents I(Ks) and I(Kr), respectively.	Potassium	112-114	potassium voltage-gated channel subfamily KQT member 1	Oryctolagus cuniculus	0-5
23241319-1	2013	KCNQ1 and hERG encode the voltage-gated potassium channel alpha-subunits of the cardiac repolarizing currents I(Ks) and I(Kr), respectively.	Potassium	112-114	ETS transcription factor ERG	Homo sapiens	10-14
23241319-4	2013	Biochemical assays indicated direct, protein-protein interactions between KCNQ1 and hERG may underlie the interplay between I(Ks) and I(Kr).	Potassium	126-128	potassium voltage-gated channel subfamily KQT member 1	Oryctolagus cuniculus	74-79
23241319-4	2013	Biochemical assays indicated direct, protein-protein interactions between KCNQ1 and hERG may underlie the interplay between I(Ks) and I(Kr).	Potassium	126-128	ETS transcription factor ERG	Homo sapiens	84-88
23789440-1	2013	Ion-regulating renal function and influence of vasopressin and its analogues on the rate and selectiveness of the urinary potassium excretion were investigated after short-term parenteral and oral potassium loading.	Potassium	122-131	arginine vasopressin	Rattus norvegicus	47-58
23789440-5	2013	Desmopressin and 1-deamino-Arg4-vasotocin prevented rise of diuresis, natriuresis and magniuresis under these conditions; 1-deamino-Arg4-vasotocin and vasopressin stimulated urinary potassium excretion during first 30 min after loading.	Potassium	182-191	arginine vasopressin	Rattus norvegicus	151-162
23439557-5	2013	Cesium induces expression of a high-affinity potassium transporter gene HAK5 and reduces potassium content in the plant body, suggesting a competitive nature of potassium and cesium uptake in plants.	Potassium	45-54	high affinity K+ transporter 5	Arabidopsis thaliana	72-76
23142267-9	2013	Moreover, we found a significant increase in the S100B secretion basal levels with the increasing of animal age and the incubation with high levels of potassium resulted in a decrease of S100B secretion in 30 and 90-day old rats.	Potassium	151-160	S100 calcium binding protein B	Rattus norvegicus	49-54
23195681-0	2013	Kidney-specific WNK1 regulates sodium reabsorption and potassium secretion in mouse cortical collecting duct.	Potassium	55-64	WNK lysine deficient protein kinase 1	Mus musculus	16-20
23195681-6	2013	Compared with that in wild-type tubules, K(+) secretion was reduced in KS-WNK1 knockout CCD perfused at a low luminal fluid rate of ~1.5 nl/min.	Potassium	71-73	WNK lysine deficient protein kinase 1	Mus musculus	74-78
23195681-7	2013	Na(+) reabsorption and the lumen-negative transepithelial potential difference were also lower in the KS-WNK1 knockout CCD compared with control CCD.	Potassium	102-104	WNK lysine deficient protein kinase 1	Mus musculus	105-109
23195681-12	2013	In addition, KS-WNK1 plays a role in regulating Na(+) transport in the CCD.	Potassium	13-15	WNK lysine deficient protein kinase 1	Mus musculus	16-20
22185904-8	2013	Half-blocking concentration of sodium and potassium currents were 43 muM and 557 muM; Hill coefficient was 1.1 and 0.9, respectively.	Potassium	42-51	latexin	Homo sapiens	81-84
23267025-6	2013	LL-37 activation of the NLRP3 inflammasome utilizes P2X7 receptor-mediated potassium efflux.	Potassium	75-84	cathelicidin antimicrobial peptide	Homo sapiens	0-5
23267025-6	2013	LL-37 activation of the NLRP3 inflammasome utilizes P2X7 receptor-mediated potassium efflux.	Potassium	75-84	NLR family pyrin domain containing 3	Homo sapiens	24-29
23267025-6	2013	LL-37 activation of the NLRP3 inflammasome utilizes P2X7 receptor-mediated potassium efflux.	Potassium	75-84	purinergic receptor P2X 7	Homo sapiens	52-65
23396830-9	2013	We propose that the KUP6 subfamily transporters act as key factors in osmotic adjustment by balancing potassium homeostasis in cell growth and drought stress responses.	Potassium	102-111	K+ uptake permease 6	Arabidopsis thaliana	20-24
23318498-7	2013	The shortening of the action potential was related to an increase of potassium current which was measured in isolated ventricular myocytes before and after intracellular dialysis of renin (10(-9)M) using a voltage whole cell clamp configuration.	Potassium	69-78	renin	Rattus norvegicus	182-187
23318498-8	2013	Valsartan (10(-8)M) dialyzed together with renin (120pM) into the cell decreased drastically the effect of renin on potassium current.	Potassium	116-125	renin	Rattus norvegicus	43-48
23318498-8	2013	Valsartan (10(-8)M) dialyzed together with renin (120pM) into the cell decreased drastically the effect of renin on potassium current.	Potassium	116-125	renin	Rattus norvegicus	107-112
23318498-9	2013	An increment of potassium current was also found when intracellular renin was dialyzed into cardiomyocytes exposed to Krebs solution containing valsartan (10(-8)M) for 10min prior to renin administration.	Potassium	16-25	renin	Rattus norvegicus	68-73
23318498-9	2013	An increment of potassium current was also found when intracellular renin was dialyzed into cardiomyocytes exposed to Krebs solution containing valsartan (10(-8)M) for 10min prior to renin administration.	Potassium	16-25	renin	Rattus norvegicus	183-188
23318498-10	2013	Bis-1 which is a specific inhibitor of PKC, abolished the effect of intracellular renin on potassium current.	Potassium	91-100	renin	Rattus norvegicus	82-87
23318498-13	2013	The effect of renin on total potassium currents was inhibited by valsartan and by Bis-1.	Potassium	29-38	renin	Rattus norvegicus	14-19
22185904-8	2013	Half-blocking concentration of sodium and potassium currents were 43 muM and 557 muM; Hill coefficient was 1.1 and 0.9, respectively.	Potassium	42-51	latexin	Homo sapiens	69-72
23382593-4	2013	Based on the circadian expression of KChIP2, we can accurately predict the circadian rhythm in cardiac electrical activity and suggest the transient outward potassium currents as the key current for circadian rhythmicity.	Potassium	157-166	potassium voltage-gated channel interacting protein 2	Homo sapiens	37-43
23135699-3	2013	Switching from SMB to SMA MHC protein expression decreased the rate of the force transient and increased the sustained tonic force in SMB((-/-)) ileum and antrum with high potassium (KPSS) but not with carbachol (CCh) stimulation.	Potassium	172-181	immunoglobulin mu binding protein 2	Mus musculus	22-25
23142267-9	2013	Moreover, we found a significant increase in the S100B secretion basal levels with the increasing of animal age and the incubation with high levels of potassium resulted in a decrease of S100B secretion in 30 and 90-day old rats.	Potassium	151-160	S100 calcium binding protein B	Rattus norvegicus	187-192
23221912-0	2013	Role of the activation gate in determining the extracellular potassium dependency of block of HERG by trapped drugs.	Potassium	61-70	potassium voltage-gated channel subfamily H member 2	Homo sapiens	94-98
23240720-0	2013	HIV-1 Vpu protein mediates the transport of potassium in Saccharomyces cerevisiae.	Potassium	44-53	Vpu	Human immunodeficiency virus 1	6-9
23224874-2	2013	Na(+)/Ca(2+) exchangers, NCX and NCKX, play a critical role in the transport of one [Ca(2+)](i) and potassium ion across the cell membrane in exchange for four extracellular sodium ions [Na(+)](e).	Potassium	100-109	T cell leukemia homeobox 2	Homo sapiens	25-28
23224874-2	2013	Na(+)/Ca(2+) exchangers, NCX and NCKX, play a critical role in the transport of one [Ca(2+)](i) and potassium ion across the cell membrane in exchange for four extracellular sodium ions [Na(+)](e).	Potassium	100-109	solute carrier family 24 member 1	Homo sapiens	33-37
23224874-3	2013	Mammalian plasma membrane Na(+)/Ca(2+) exchange proteins are divided into two families: one in which Ca(2+) flux is dependent only on sodium (NCX1-3) and another in which Ca(2+) flux is also dependent on potassium (NCKX1-4).	Potassium	204-213	solute carrier family 8 member A1	Homo sapiens	142-148
24429825-0	2013	Co-regulated pendrin and aquaporin 5 expression and trafficking in Type-B intercalated cells under potassium depletion.	Potassium	99-108	solute carrier family 26, member 4	Mus musculus	13-20
24429825-0	2013	Co-regulated pendrin and aquaporin 5 expression and trafficking in Type-B intercalated cells under potassium depletion.	Potassium	99-108	aquaporin 5	Mus musculus	25-36
23037322-7	2013	HDL-C and Apo A-I were positively correlated with Ks (r = 0.52, P &lt; 0.00001 and r = 0.44, P &lt; 0.00001, respectively) and inversely with t50% (r = -0.44, P &lt; 0.00001 and r = -0.35, P = 0.00003, respectively).	Potassium	50-52	apolipoprotein A1	Homo sapiens	10-17
23037322-9	2013	Ks and t50% were associated with Lp(a) (r = -0.42, P &lt; 0.00001 and r = 0.42, P &lt; 0.00001, respectively) and fibrinogen (r = -0.31, P = 0.00024 and r = 0.39, P &lt; 0.00001, respectively).	Potassium	0-2	lipoprotein(a)	Homo sapiens	33-38
23037322-9	2013	Ks and t50% were associated with Lp(a) (r = -0.42, P &lt; 0.00001 and r = 0.42, P &lt; 0.00001, respectively) and fibrinogen (r = -0.31, P = 0.00024 and r = 0.39, P &lt; 0.00001, respectively).	Potassium	0-2	fibrinogen beta chain	Homo sapiens	114-124
23221912-4	2013	Extracellular potassium influences HERG channel inactivation and can alter block of HERG by some drugs.	Potassium	14-23	potassium voltage-gated channel subfamily H member 2	Homo sapiens	35-39
23221912-4	2013	Extracellular potassium influences HERG channel inactivation and can alter block of HERG by some drugs.	Potassium	14-23	potassium voltage-gated channel subfamily H member 2	Homo sapiens	84-88
23221912-7	2013	We also show that bepridil block of the HERG mutant D540K, a mutant channel that is unable to trap drugs, is dependent on extracellular potassium, correlates with the permeant ion, and is independent of HERG inactivation.	Potassium	136-145	potassium voltage-gated channel subfamily H member 2	Homo sapiens	40-44
23221912-8	2013	These results suggest that the lack of extracellular potassium dependency of block of HERG by some drugs may in part be related to the ability of these drugs to be trapped inside the channel after the channel closes.	Potassium	53-62	potassium voltage-gated channel subfamily H member 2	Homo sapiens	86-90
22999866-5	2013	Patch-clamp studies displayed outward potassium currents, probably carried through Kir6.1 channels.	Potassium	38-47	potassium inwardly-rectifying channel, subfamily J, member 8	Mus musculus	83-89
22193336-2	2013	AQP4 has been hypothesized to modulate water and potassium fluxes associated with neuronal activity in pathophysiological states.	Potassium	49-58	aquaporin 4	Mus musculus	0-4
23059770-0	2013	Common variation in with no-lysine kinase 1 (WNK1) and blood pressure responses to dietary sodium or potassium interventions- family-based association study.	Potassium	101-110	WNK lysine deficient protein kinase 1	Homo sapiens	45-49
23059770-2	2013	The aim of this study was to identify the effect of common WNK1 variants on the shift of BP during strict dietary interventions of salt or potassium intake.	Potassium	139-148	WNK lysine deficient protein kinase 1	Homo sapiens	59-63
23059770-7	2013	CONCLUSIONS: The WNK1 gene might be mechanistically involved in the variation in BP response to dietary sodium and potassium intake among individuals, and might contribute to the variation of this complex phenotype.	Potassium	115-124	WNK lysine deficient protein kinase 1	Homo sapiens	17-21
23165113-0	2013	Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron.	Potassium	56-65	angiotensinogen	Homo sapiens	11-25
23165113-1	2013	PURPOSE OF REVIEW: The aim is to review the recently reported effects of angiotensin II (Ang II) on sodium and potassium transport in the aldosterone-sensitive distal nephron, including the signaling pathways between receptor and transporter, and the (patho)physiological implications of these findings.	Potassium	111-120	angiotensinogen	Homo sapiens	73-87
23165113-1	2013	PURPOSE OF REVIEW: The aim is to review the recently reported effects of angiotensin II (Ang II) on sodium and potassium transport in the aldosterone-sensitive distal nephron, including the signaling pathways between receptor and transporter, and the (patho)physiological implications of these findings.	Potassium	111-120	angiotensinogen	Homo sapiens	89-95
23165113-8	2013	SUMMARY: The effects of Ang II on NCC, ENaC, and ROMK help explain the renal response to hypovolemia which is to conserve both sodium and potassium.	Potassium	138-147	angiotensinogen	Homo sapiens	24-30
23106642-7	2013	Apelin (1 nM) increased sodium currents, ultra-rapid potassium currents and the reverse mode of sodium-calcium exchanger currents, but decreased late sodium currents and L-type calcium currents and did not change transient outward currents or inward rectifier potassium currents in LA myocytes.	Potassium	53-62	APLN	Oryctolagus cuniculus	0-6
24069049-14	2013	GA significantly inhibited the potassium currents in a dose- and voltage-dependent manner, suggesting that it exerts its antiarrhythmic action through the prolongation of APD and ERP owing to the inhibition of I K (I Kr, I Ks) and HERG K(+) channel.	Potassium	31-40	potassium voltage-gated channel subfamily H member 2	Homo sapiens	231-235
23292580-9	2013	Change in serum potassium among patients with hyperkalemia was 4.0 +- 0.5 mEq/L before TxK and 5.3 +- 0.7 mEq/L after TxK.	Potassium	16-25	TXK tyrosine kinase	Homo sapiens	87-90
23554830-0	2013	Saikosaponin a Enhances Transient Inactivating Potassium Current in Rat Hippocampal CA1 Neurons.	Potassium	47-56	carbonic anhydrase 1	Rattus norvegicus	84-87
23292580-9	2013	Change in serum potassium among patients with hyperkalemia was 4.0 +- 0.5 mEq/L before TxK and 5.3 +- 0.7 mEq/L after TxK.	Potassium	16-25	TXK tyrosine kinase	Homo sapiens	118-121
23577126-8	2013	We found that a significant portion of resting membrane potassium permeability in wild-type sperm was contributed by SLO3 K(+) channels.	Potassium	56-65	potassium channel, subfamily U, member 1	Mus musculus	117-121
23165302-7	2013	Finally, a role of angiotensin II in sodium and potassium handling in the distal nephron has been identified.	Potassium	48-57	angiotensinogen	Homo sapiens	19-33
23109687-0	2013	A protein kinase, calcineurin B-like protein-interacting protein Kinase9, interacts with calcium sensor calcineurin B-like Protein3 and regulates potassium homeostasis under low-potassium stress in Arabidopsis.	Potassium	146-155	SNF1-related protein kinase 2.2	Arabidopsis thaliana	2-16
23109687-0	2013	A protein kinase, calcineurin B-like protein-interacting protein Kinase9, interacts with calcium sensor calcineurin B-like Protein3 and regulates potassium homeostasis under low-potassium stress in Arabidopsis.	Potassium	178-187	SNF1-related protein kinase 2.2	Arabidopsis thaliana	2-16
23099443-5	2013	The hKv1.3-E314 antibody that we had generated as a specific hKv1.3 blocker inhibited outward delayed rectifier potassium currents, whereas the hKv1.5-E313 antibody that we had generated as a specific hKv1.5 blocker failed.	Potassium	112-121	potassium voltage-gated channel subfamily A member 3	Homo sapiens	4-10
23099443-5	2013	The hKv1.3-E314 antibody that we had generated as a specific hKv1.3 blocker inhibited outward delayed rectifier potassium currents, whereas the hKv1.5-E313 antibody that we had generated as a specific hKv1.5 blocker failed.	Potassium	112-121	potassium voltage-gated channel subfamily A member 3	Homo sapiens	61-67
23633957-10	2013	HCV uptake concomitantly induces a potassium efflux that activates the NLRP3 inflammasome for IL-1beta processing and secretion.	Potassium	35-44	NLR family pyrin domain containing 3	Homo sapiens	71-76
23633957-10	2013	HCV uptake concomitantly induces a potassium efflux that activates the NLRP3 inflammasome for IL-1beta processing and secretion.	Potassium	35-44	interleukin 1 beta	Homo sapiens	94-102
23084712-10	2012	Potassium intake was positively correlated with Cornell VDP (r = 0.119, p &lt; 0.05), CAIx (r = 0.178, p &lt; 0.01) and PAIx (r = 0.202, p &lt; 0.01).	Potassium	0-9	carbonic anhydrase 9	Homo sapiens	86-90
23109340-0	2012	The structure of Sec12 implicates potassium ion coordination in Sar1 activation.	Potassium	34-43	Sar family guanine nucleotide exchange factor SEC12	Saccharomyces cerevisiae S288C	17-22
23109340-0	2012	The structure of Sec12 implicates potassium ion coordination in Sar1 activation.	Potassium	34-43	Arf family GTPase SAR1	Saccharomyces cerevisiae S288C	64-68
23000022-8	2012	Co-expression of G325R and WT KCNQ1 with KCNE1 shifted the voltage-dependence of I(Ks) activation by 12.0mV, indicating co-assembly of mutant and WT subunits.	Potassium	83-85	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	30-35
23000022-8	2012	Co-expression of G325R and WT KCNQ1 with KCNE1 shifted the voltage-dependence of I(Ks) activation by 12.0mV, indicating co-assembly of mutant and WT subunits.	Potassium	83-85	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	41-46
23220438-1	2012	We report a unique case of diabetic ketoacidosis in which a relatively low potassium level on admission was associated with consequent life-threatening and refractory arrhythmia secondary to inappropriate use of intravenous insulin and bicarbonate therapy.	Potassium	75-84	insulin	Homo sapiens	224-231
22948499-6	2012	In contrast to S. cerevisiae, Z. rouxii cells without the TRK1 gene contained less potassium than the control cells and their plasma membrane was significantly hyperpolarized compared with those of the parental strain when grown in the presence of 100 mM KCl.	Potassium	83-92	Trk1p	Saccharomyces cerevisiae S288C	58-62
22997256-6	2012	Activation of NLRP3 required phagocytosis of uromodulin particles into lysosomes, cathepsin leakage, oxidative stress, and potassium efflux from the cell.	Potassium	123-132	NLR family pyrin domain containing 3	Homo sapiens	14-19
23232097-4	2012	Plants lacking UBP16 were hypersensitive to salt stress and accumulated more sodium and less potassium.	Potassium	93-102	ubiquitin-specific protease 16	Arabidopsis thaliana	15-20
23102642-6	2012	Laboratory studies revealed a low serum potassium level at 2.8 mmol/L associated with high urinary potassium excretion (84 mmol/24h) and a very high aldosterone/renin ratio (&gt;462).	Potassium	40-49	renin	Homo sapiens	161-166
22156575-6	2012	We speculate that KCTD8 might modulate adverse effects of smoking during pregnancy on brain development via apoptosis triggered by low intracellular levels of potassium, possibly reducing the number of progenitor cells.	Potassium	159-168	potassium channel tetramerization domain containing 8	Homo sapiens	18-23
23197740-7	2012	Intracellular recordings from ex vivo dorsal root ganglion preparations revealed that Kv9.1 knock-down was linked to lowered firing thresholds and increased firing rates under physiologically relevant conditions of extracellular potassium accumulation during prolonged activity.	Potassium	229-238	potassium voltage-gated channel, modifier subfamily S, member 1	Rattus norvegicus	86-91
22918120-4	2012	Genetic inactivation of one of the genes identified by our strategy, dickkopf-3 (Dkk3), whose expression is increased by calcium influx into adrenocortical cells, in the Kcnk3 null background results in the extension of the low-renin, potassium-rich diet insensitive hyperaldosteronemic phenotype to the male sex.	Potassium	235-244	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	69-79
22918120-4	2012	Genetic inactivation of one of the genes identified by our strategy, dickkopf-3 (Dkk3), whose expression is increased by calcium influx into adrenocortical cells, in the Kcnk3 null background results in the extension of the low-renin, potassium-rich diet insensitive hyperaldosteronemic phenotype to the male sex.	Potassium	235-244	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	81-85
22989884-3	2012	Once activated by WNK1, OSR1 and SPAK phosphorylate and stimulate the sodium, potassium, two chloride co-transporters, NKCC1 and NKCC2, and also affect other related ion co-transporters.	Potassium	78-87	WNK lysine deficient protein kinase 1	Homo sapiens	18-22
22989884-3	2012	Once activated by WNK1, OSR1 and SPAK phosphorylate and stimulate the sodium, potassium, two chloride co-transporters, NKCC1 and NKCC2, and also affect other related ion co-transporters.	Potassium	78-87	oxidative stress responsive kinase 1	Homo sapiens	24-28
22989884-3	2012	Once activated by WNK1, OSR1 and SPAK phosphorylate and stimulate the sodium, potassium, two chloride co-transporters, NKCC1 and NKCC2, and also affect other related ion co-transporters.	Potassium	78-87	serine/threonine kinase 39	Homo sapiens	33-37
22989884-3	2012	Once activated by WNK1, OSR1 and SPAK phosphorylate and stimulate the sodium, potassium, two chloride co-transporters, NKCC1 and NKCC2, and also affect other related ion co-transporters.	Potassium	78-87	solute carrier family 12 member 2	Homo sapiens	119-124
22989884-3	2012	Once activated by WNK1, OSR1 and SPAK phosphorylate and stimulate the sodium, potassium, two chloride co-transporters, NKCC1 and NKCC2, and also affect other related ion co-transporters.	Potassium	78-87	solute carrier family 12 member 1	Homo sapiens	129-134
22736459-1	2012	Spinocerebellar ataxia type 13 (SCA13) is an autosomal dominant disease caused by mutations in the Kv3.3 voltage-gated potassium (K(+)) channel.	Potassium	119-128	potassium voltage-gated channel subfamily C member 3	Homo sapiens	99-104
23039231-4	2012	Lack of potassium drastically alters sulfur metabolism (mainly Met and Cys metabolism), triggers an oxidative stress response and activates the retrograde pathway, possibly due to the ammonium accumulation that occurs through the Trk1 potassium transporter.	Potassium	8-17	Trk1p	Saccharomyces cerevisiae S288C	230-234
23039231-6	2012	Only specific subsets of these changes were observed in a strain deleted for the TRK1 and TRK2 genes growing in the presence of sufficient potassium (50 mM).	Potassium	139-148	Trk1p	Saccharomyces cerevisiae S288C	81-85
23039231-6	2012	Only specific subsets of these changes were observed in a strain deleted for the TRK1 and TRK2 genes growing in the presence of sufficient potassium (50 mM).	Potassium	139-148	Trk2p	Saccharomyces cerevisiae S288C	90-94
23063532-0	2012	Mechanical stretch reduces the effect of angiotensin II on potassium current in cardiac ventricular cells of adult Sprague Dawley rats.	Potassium	59-68	angiotensinogen	Rattus norvegicus	41-55
23063532-2	2012	The influence of mechanical stretch on the effect of angiotensin II (Ang II) on potassium current was investigated on cardiomyocytes isolated from the left ventricle of adult Sprague Dawley rats.	Potassium	80-89	angiotensinogen	Rattus norvegicus	53-67
23063532-2	2012	The influence of mechanical stretch on the effect of angiotensin II (Ang II) on potassium current was investigated on cardiomyocytes isolated from the left ventricle of adult Sprague Dawley rats.	Potassium	80-89	angiotensinogen	Rattus norvegicus	69-75
23063532-5	2012	In conclusion, the mechanical stretch of cardiomyocytes increases the potassium currents, an effect greatly dependent on the mechanical activation of AT1 receptors independently of Ang II.	Potassium	70-79	angiotensin II receptor, type 1a	Rattus norvegicus	150-153
23063532-6	2012	In addition, the increment of potassium currents caused by Ang II was greatly reduced by mechanical stretch, an effect abolished by protein kinase C inhibition.	Potassium	30-39	angiotensinogen	Rattus norvegicus	59-65
22481627-3	2012	Elevated extracellular potassium to levels occurring around hyperactive neurons affects both gap junction and pannexin1 channels.	Potassium	23-32	pannexin 1	Homo sapiens	110-119
22976302-7	2012	In the present study, GABA and SDF-1 are shown to exert opposite effects on the speed of cell movement by activating depolarizing or hyperpolarizing signaling pathways, GABA via changes in chloride and SDF-1 via changes in potassium.	Potassium	223-232	C-X-C motif chemokine ligand 12	Homo sapiens	31-36
22481627-6	2012	Pannexin1 can be activated by elevations in extracellular potassium through a mechanism that is quite different.	Potassium	58-67	pannexin 1	Homo sapiens	0-9
23082064-7	2012	At the cell level, ginsenoside Rb1 increased outward potassium currents, and IK(V) was enhanced from 1137.71 +- 171.62 pA to 1449.73 +- 162.39 pA by 50 mumol/L Rb1 at +60 mV (n = 6, P &lt; 0.05).	Potassium	53-62	RB transcriptional corepressor 1	Mus musculus	31-34
23373225-3	2012	RESULT: On the 7th day, the neuron-like cells derived from ginsenoside Rg1 (20 mg x L(-1))-induced NSCs show: (1) The resting membrane potential: (-45.70 +/- 2.63) mV, the membrane capacitance: (26.89 +/- 1.91) pF, the membrane input impedance: (877.51 +/- 20.44) MH (P &lt; 0.05 compared with the control group, respectively); (2) The detection rate of inward sodium current which is rapidly activated and inactivated in voltage-dependence was 50%, and its average peak value was (711.48 +/- 158.03) pA (P &lt; 0.05 compared with the control group); (3) The outward potassium currents were composed of rapidly activated and inactivated transient outward potassium current and delayed rectifier outward potassium current, and its average peak value was (1 070.42 +/- 177.18) pA (P &lt; 0.05 compared with the control group).	Potassium	567-576	protein phosphatase 1 regulatory subunit 3A	Homo sapiens	71-74
23373225-3	2012	RESULT: On the 7th day, the neuron-like cells derived from ginsenoside Rg1 (20 mg x L(-1))-induced NSCs show: (1) The resting membrane potential: (-45.70 +/- 2.63) mV, the membrane capacitance: (26.89 +/- 1.91) pF, the membrane input impedance: (877.51 +/- 20.44) MH (P &lt; 0.05 compared with the control group, respectively); (2) The detection rate of inward sodium current which is rapidly activated and inactivated in voltage-dependence was 50%, and its average peak value was (711.48 +/- 158.03) pA (P &lt; 0.05 compared with the control group); (3) The outward potassium currents were composed of rapidly activated and inactivated transient outward potassium current and delayed rectifier outward potassium current, and its average peak value was (1 070.42 +/- 177.18) pA (P &lt; 0.05 compared with the control group).	Potassium	655-664	protein phosphatase 1 regulatory subunit 3A	Homo sapiens	71-74
23373225-3	2012	RESULT: On the 7th day, the neuron-like cells derived from ginsenoside Rg1 (20 mg x L(-1))-induced NSCs show: (1) The resting membrane potential: (-45.70 +/- 2.63) mV, the membrane capacitance: (26.89 +/- 1.91) pF, the membrane input impedance: (877.51 +/- 20.44) MH (P &lt; 0.05 compared with the control group, respectively); (2) The detection rate of inward sodium current which is rapidly activated and inactivated in voltage-dependence was 50%, and its average peak value was (711.48 +/- 158.03) pA (P &lt; 0.05 compared with the control group); (3) The outward potassium currents were composed of rapidly activated and inactivated transient outward potassium current and delayed rectifier outward potassium current, and its average peak value was (1 070.42 +/- 177.18) pA (P &lt; 0.05 compared with the control group).	Potassium	655-664	protein phosphatase 1 regulatory subunit 3A	Homo sapiens	71-74
23115170-6	2012	The properties of this current matched that of the native Slack potassium current, which was identified using an siRNA approach.	Potassium	64-73	potassium sodium-activated channel subfamily T member 1	Homo sapiens	58-63
23090492-1	2012	Inwardly rectifying potassium channels (Kir) are a special subset of potassium selective ion channels which pass potassium more easily into rather than out of the cell.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	40-43
22908235-1	2012	The co-assembly of KCNQ1 with KCNE1 produces I(KS), a K(+) current, crucial for the repolarization of the cardiac action potential.	Potassium	47-49	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	19-24
22989185-1	2012	The human ether-a-go-go related gene 1 (hERG1) K ion channel is a key element for the rapid component of the delayed rectified potassium current in cardiac myocytes.	Potassium	127-136	potassium voltage-gated channel subfamily H member 2	Homo sapiens	40-45
22908235-1	2012	The co-assembly of KCNQ1 with KCNE1 produces I(KS), a K(+) current, crucial for the repolarization of the cardiac action potential.	Potassium	47-49	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	30-35
22771251-7	2012	The activity of the antioxidative enzymes SOD, peroxidase and APX in potassium deprivation significantly increased, whereas CAT and DHAR activity was significantly depressed in the potassium starvation treatment compared to controls.	Potassium	69-78	iron superoxide dismutase	Solanum lycopersicum	42-45
22713745-3	2012	In the latter, CPE can bind to internal organs such as the liver, which induces lethal potassium levels in blood.	Potassium	87-96	cpe	Clostridium perfringens	15-18
22771251-7	2012	The activity of the antioxidative enzymes SOD, peroxidase and APX in potassium deprivation significantly increased, whereas CAT and DHAR activity was significantly depressed in the potassium starvation treatment compared to controls.	Potassium	181-190	dehydroascorbate reductase	Solanum lycopersicum	132-136
23035098-7	2012	In stark contrast, NRG1 had minor effects on whole-cell potassium currents.	Potassium	56-65	neuregulin 1	Rattus norvegicus	19-23
22728096-4	2012	The IL-1beta release depended on potassium efflux but was independent of reactive oxygen generation of bovine monocytes.	Potassium	33-42	interleukin 1 beta	Bos taurus	4-12
21404100-4	2012	The finding of abnormal potassium levels (low or high) in the presence of suppressed renin secretion, and metabolic alkalosis or acidosis should prompt consideration of these familial diseases.	Potassium	24-33	renin	Homo sapiens	85-90
22917023-9	2012	A linear calibration curve for the coulometric cell with valinomycin potassium-selective membrane was obtained in the range of 100 nM to 10 muM potassium in the presence of a 10 muM sodium background.	Potassium	69-78	latexin	Homo sapiens	140-143
22917023-9	2012	A linear calibration curve for the coulometric cell with valinomycin potassium-selective membrane was obtained in the range of 100 nM to 10 muM potassium in the presence of a 10 muM sodium background.	Potassium	69-78	latexin	Homo sapiens	178-181
22917023-10	2012	In the presence of a higher (100 muM) concentration of sodium, a reliable detection of 1-100 muM of potassium was achieved.	Potassium	100-109	latexin	Homo sapiens	33-36
22917023-10	2012	In the presence of a higher (100 muM) concentration of sodium, a reliable detection of 1-100 muM of potassium was achieved.	Potassium	100-109	latexin	Homo sapiens	93-96
22508963-13	2012	In conclusion, increased I(Ks) due to the KCNQ1 S140G mutation increases atrial susceptibility to arrhythmia due to increased tissue vulnerability, shortened ERP and altered atrial conduction velocity, which, in combination, facilitate initiation and maintenance of re-entrant excitation waves.	Potassium	27-29	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	42-47
22771251-7	2012	The activity of the antioxidative enzymes SOD, peroxidase and APX in potassium deprivation significantly increased, whereas CAT and DHAR activity was significantly depressed in the potassium starvation treatment compared to controls.	Potassium	69-78	peroxidase	Solanum lycopersicum	47-57
22771251-7	2012	The activity of the antioxidative enzymes SOD, peroxidase and APX in potassium deprivation significantly increased, whereas CAT and DHAR activity was significantly depressed in the potassium starvation treatment compared to controls.	Potassium	69-78	cytosolic ascorbate peroxidase 2	Solanum lycopersicum	62-65
22771251-7	2012	The activity of the antioxidative enzymes SOD, peroxidase and APX in potassium deprivation significantly increased, whereas CAT and DHAR activity was significantly depressed in the potassium starvation treatment compared to controls.	Potassium	181-190	catalase isozyme 1	Solanum lycopersicum	124-127
22840709-2	2012	In the presence of potassium ion, AS1411 folded to G-quadruplex structure, binded fluorescent ligand (PPIX) with fluorescent enhancement, and targeted the nucleolin overexpressed by cancer cells.	Potassium	19-28	nucleolin	Homo sapiens	155-164
22931498-1	2012	Seven potassium Boc-protected secondary aminomethyltrifluoroborates were prepared in a standardized two-step process.	Potassium	6-15	BOC cell adhesion associated, oncogene regulated	Homo sapiens	16-19
22820370-9	2012	SUMMARY: Modulation of WNK4 activity by AngII underlies the effects of AngII on NCC activity and this is probably important for the stimulation of renal sodium retention, as well as for the prevention of potassium loss, during hypovolemia.	Potassium	204-213	WNK lysine deficient protein kinase 4	Homo sapiens	23-27
23020479-5	2012	A Hodgkin-Huxley-style cardiac ionic model captured the different types of complex dynamics following blockage of the hERG mediated potassium current.	Potassium	132-141	ETS transcription factor ERG	Homo sapiens	118-122
22914841-1	2012	OBJECTIVE: To electrophysiologically characterize the Na(v)1.4 mutant N440K found in a Korean family with a syndrome combining symptoms of paramyotonia congenita, hyperkalemic periodic paralysis, and potassium-aggravated myotonia.	Potassium	200-209	immunoglobulin lambda variable 2-14	Homo sapiens	54-62
22791335-3	2012	The role of KS-WNK1 in other nephron segments is less clear.	Potassium	12-14	WNK lysine deficient protein kinase 1	Mus musculus	15-19
22820370-9	2012	SUMMARY: Modulation of WNK4 activity by AngII underlies the effects of AngII on NCC activity and this is probably important for the stimulation of renal sodium retention, as well as for the prevention of potassium loss, during hypovolemia.	Potassium	204-213	angiotensinogen	Homo sapiens	40-45
22820370-9	2012	SUMMARY: Modulation of WNK4 activity by AngII underlies the effects of AngII on NCC activity and this is probably important for the stimulation of renal sodium retention, as well as for the prevention of potassium loss, during hypovolemia.	Potassium	204-213	angiotensinogen	Homo sapiens	71-76
22828404-2	2012	Recently we showed that administration of a selective GPR30 agonist (G-1) to ovariectomized rats enhanced acquisition of a delayed matching-to-position (DMP) T-maze task and increased potassium-stimulated acetylcholine release in the hippocampus, similar to estradiol (E2) (Hammond et al., 2009).	Potassium	184-193	G protein-coupled estrogen receptor 1	Rattus norvegicus	54-59
22969707-2	2012	Further upstream, in the lateral superior olive (LSO), absence of low-threshold potassium currents in Kcna1(-/-) mice interfered with response onset timing and restricted IID-sensitivity to the hemifield of the excitatory ear.	Potassium	80-89	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	102-107
22575762-5	2012	Cells cotransduced with Tbx5, Mef2c, Myocd expressed cardiac contractile proteins, had cardiac-like potassium and sodium currents and action potentials could be elicited.	Potassium	100-109	T-box 5	Mus musculus	24-28
22575762-5	2012	Cells cotransduced with Tbx5, Mef2c, Myocd expressed cardiac contractile proteins, had cardiac-like potassium and sodium currents and action potentials could be elicited.	Potassium	100-109	myocyte enhancer factor 2C	Mus musculus	30-35
22575762-5	2012	Cells cotransduced with Tbx5, Mef2c, Myocd expressed cardiac contractile proteins, had cardiac-like potassium and sodium currents and action potentials could be elicited.	Potassium	100-109	myocardin	Mus musculus	37-42
22406475-0	2012	The Arabidopsis AP2/ERF transcription factor RAP2.11 modulates plant response to low-potassium conditions.	Potassium	85-94	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	16-19
22406475-2	2012	The transcription factor RAP2.11 was identified as a component in the response to low potassium through regulation of the high-affinity K(+) uptake transporter AtHAK5 and other components of the low-potassium signal transduction pathway.	Potassium	86-95	high affinity K+ transporter 5	Arabidopsis thaliana	160-166
22406475-2	2012	The transcription factor RAP2.11 was identified as a component in the response to low potassium through regulation of the high-affinity K(+) uptake transporter AtHAK5 and other components of the low-potassium signal transduction pathway.	Potassium	199-208	high affinity K+ transporter 5	Arabidopsis thaliana	160-166
22406475-3	2012	RAP2.11 was identified through the activation tagging of Arabidopsis lines that contained a luciferase marker driven by the AtHAK5 promoter that is normally only induced by low potassium.	Potassium	177-186	high affinity K+ transporter 5	Arabidopsis thaliana	124-130
22778270-2	2012	In heart, Yotiao directly associates with the slow outward potassium ion current (I(Ks)) and recruits both PKA and PP1 to regulate I(Ks) phosphorylation and gating.	Potassium	59-68	A-kinase anchoring protein 9	Homo sapiens	10-16
22778270-2	2012	In heart, Yotiao directly associates with the slow outward potassium ion current (I(Ks)) and recruits both PKA and PP1 to regulate I(Ks) phosphorylation and gating.	Potassium	84-86	A-kinase anchoring protein 9	Homo sapiens	10-16
22778270-2	2012	In heart, Yotiao directly associates with the slow outward potassium ion current (I(Ks)) and recruits both PKA and PP1 to regulate I(Ks) phosphorylation and gating.	Potassium	133-135	A-kinase anchoring protein 9	Homo sapiens	10-16
22778270-2	2012	In heart, Yotiao directly associates with the slow outward potassium ion current (I(Ks)) and recruits both PKA and PP1 to regulate I(Ks) phosphorylation and gating.	Potassium	133-135	protein phosphatase 1 catalytic subunit gamma	Mus musculus	115-118
22778270-3	2012	Human mutations that disrupt I(Ks)-Yotiao interaction result in reduced PKA-dependent phosphorylation of the I(Ks) subunit KCNQ1 and inhibition of sympathetic stimulation of I(Ks), which can give rise to long-QT syndrome.	Potassium	31-33	A-kinase anchoring protein 9	Homo sapiens	35-41
22778270-3	2012	Human mutations that disrupt I(Ks)-Yotiao interaction result in reduced PKA-dependent phosphorylation of the I(Ks) subunit KCNQ1 and inhibition of sympathetic stimulation of I(Ks), which can give rise to long-QT syndrome.	Potassium	31-33	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	123-128
22778270-3	2012	Human mutations that disrupt I(Ks)-Yotiao interaction result in reduced PKA-dependent phosphorylation of the I(Ks) subunit KCNQ1 and inhibition of sympathetic stimulation of I(Ks), which can give rise to long-QT syndrome.	Potassium	111-113	A-kinase anchoring protein 9	Homo sapiens	35-41
22778270-3	2012	Human mutations that disrupt I(Ks)-Yotiao interaction result in reduced PKA-dependent phosphorylation of the I(Ks) subunit KCNQ1 and inhibition of sympathetic stimulation of I(Ks), which can give rise to long-QT syndrome.	Potassium	111-113	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	123-128
22778270-3	2012	Human mutations that disrupt I(Ks)-Yotiao interaction result in reduced PKA-dependent phosphorylation of the I(Ks) subunit KCNQ1 and inhibition of sympathetic stimulation of I(Ks), which can give rise to long-QT syndrome.	Potassium	111-113	A-kinase anchoring protein 9	Homo sapiens	35-41
22778270-3	2012	Human mutations that disrupt I(Ks)-Yotiao interaction result in reduced PKA-dependent phosphorylation of the I(Ks) subunit KCNQ1 and inhibition of sympathetic stimulation of I(Ks), which can give rise to long-QT syndrome.	Potassium	111-113	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	123-128
22778270-9	2012	Furthermore, the endogenous I(Ks)-Yotiao complex from guinea pig also contained AC9.	Potassium	30-32	A-kinase anchoring protein 9	Homo sapiens	34-40
22778270-9	2012	Furthermore, the endogenous I(Ks)-Yotiao complex from guinea pig also contained AC9.	Potassium	30-32	adenylate cyclase 9	Mus musculus	80-83
22778270-11	2012	Thus, in heart, Yotiao brings together PKA, PP1, PDE4D3, AC9, and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation.	Potassium	72-74	A-kinase anchoring protein 9	Homo sapiens	16-22
22212640-2	2012	Lack or inhibition of mitochondrial Cx43 is associated with reduced mitochondrial potassium influx, which might affect mitochondrial respiration.	Potassium	82-91	gap junction protein, alpha 1	Mus musculus	36-40
22668657-7	2012	Magnesium deficiency by interfering with ATPase functions causes increased intracellular calcium and sodium and decreases intracellular potassium concentration.	Potassium	136-145	dynein axonemal heavy chain 8	Homo sapiens	41-47
22799266-4	2012	This finding supports a model according to which the ACP-bound polyketide intermediate is transferred back to the KS domain on the opposite PKS strand.	Potassium	114-116	CPAT1	Homo sapiens	53-56
22421958-4	2012	Here we review our previous study of biophysical properties of I(ks) in human embryonic stem cell-derived cardiomyocytes (hESC-CMs) showed that I(ks) in hESC-CMs is a coassembly channel with a stoichiometry other than 1:1, which could be further modulated by additional KCNE1.	Potassium	65-67	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	270-275
21612807-2	2012	Potassium and glucose cellular uptake are intimately linked by insulin.	Potassium	0-9	insulin	Canis lupus familiaris	63-70
21612807-3	2012	We hypothesized that in canine hypoadrenocorticism, hyperkalaemia would stimulate insulin release as a protective mechanism, translocating potassium from the extracellular compartment to the intracellular compartment and also lower glucose concentrations.	Potassium	139-148	insulin	Canis lupus familiaris	82-89
22745159-2	2012	Among the 12 identified genes causal to heritable LQTS, ~90% of affected individuals harbor mutations in either KCNQ1 or human ether-a-go-go related genes (hERG), which encode two repolarizing potassium currents known as I(Ks) and I(Kr).	Potassium	193-202	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	112-117
23650596-2	2012	A novel GTP-hydrolysis mechanism is employed by MnmE, YqeH and FeoB, where a potassium ion plays a role analogous to the Arginine finger of the Ras-RasGAP system, to accelerate otherwise slow GTP hydrolysis rates.	Potassium	77-86	RAS p21 protein activator 1	Homo sapiens	148-154
22745159-2	2012	Among the 12 identified genes causal to heritable LQTS, ~90% of affected individuals harbor mutations in either KCNQ1 or human ether-a-go-go related genes (hERG), which encode two repolarizing potassium currents known as I(Ks) and I(Kr).	Potassium	223-225	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	112-117
22549224-3	2012	We show that ANG II and potassium induce the expression of acyl-coenzyme A (CoA) thioesterase 2 and acyl-CoA synthetase 4, two enzymes involved in intramitochondrial AA generation/export system well characterized in other steroidogenic systems.	Potassium	24-33	acyl-CoA synthetase long chain family member 4	Homo sapiens	100-121
22496411-1	2012	Dietary potassium (K(+)) restriction and hypokalemia have been reported to change the abundance of most renal Na(+) and K(+) transporters and aquaporin-2 isoform, but results have not been consistent.	Potassium	8-17	aquaporin 2	Rattus norvegicus	142-153
22168445-10	2012	CONCLUSION: Our results demonstrated for the first time that rat BMEPCs expressed intermediate-conductance Ca(2+) -activated potassium currents and volume-sensitive chloride currents, and corresponding genes and proteins of these two channels are KCNN4 and Clcn3 respectively.	Potassium	125-134	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	247-252
22747613-2	2012	In this secondary analysis, the authors tested whether this enhanced insulin response to valsartan/hydrochlorothiazide was influenced by serum potassium levels, which were reduced to a lesser extent, when compared with amlodipine/hydrochlorothiazide.	Potassium	143-152	insulin	Homo sapiens	69-76
22404309-3	2012	We found that noggin, a known antagonist of bone morphogenic protein, induces ES cells to express genes involved in serotonergic differentiation, such as Nkx2.2, Pet-1, Sonic hedgehog, tryptophan hydroxylase 2, and serotonin transporter, as well as increases high potassium-induced release of serotonin.	Potassium	264-273	noggin	Mus musculus	14-20
22418981-6	2012	Cox regression modeling found that higher baseline dietary sodium and the ratio of sodium to calorie or potassium were each independently associated with greater all-cause mortality.	Potassium	104-113	cytochrome c oxidase subunit 8A	Homo sapiens	0-3
22168445-10	2012	CONCLUSION: Our results demonstrated for the first time that rat BMEPCs expressed intermediate-conductance Ca(2+) -activated potassium currents and volume-sensitive chloride currents, and corresponding genes and proteins of these two channels are KCNN4 and Clcn3 respectively.	Potassium	125-134	chloride voltage-gated channel 3	Rattus norvegicus	257-262
22481440-5	2012	We show here that RNAi-mediated knockdown of PCSK9 significantly reduced the death of potassium-deprived cerebellar granule neurons (CGN), as shown by reduced levels of nuclear phosphorylated c-Jun and activated caspase-3, as well as condensed apoptotic nuclei.	Potassium	86-95	proprotein convertase subtilisin/kexin type 9	Homo sapiens	45-50
22481440-5	2012	We show here that RNAi-mediated knockdown of PCSK9 significantly reduced the death of potassium-deprived cerebellar granule neurons (CGN), as shown by reduced levels of nuclear phosphorylated c-Jun and activated caspase-3, as well as condensed apoptotic nuclei.	Potassium	86-95	caspase 3	Homo sapiens	212-221
26069764-2	2012	Patients with congenital NDI bearing mutations in the vasopressin 2 receptor gene, AVPR2, or in the aquaporin-2 gene, AQP2, have a pure NDI phenotype with loss of water but normal conservation of sodium, potassium, chloride and calcium.	Potassium	204-213	arginine vasopressin receptor 2	Homo sapiens	25-28
26069764-2	2012	Patients with congenital NDI bearing mutations in the vasopressin 2 receptor gene, AVPR2, or in the aquaporin-2 gene, AQP2, have a pure NDI phenotype with loss of water but normal conservation of sodium, potassium, chloride and calcium.	Potassium	204-213	aquaporin 2	Homo sapiens	100-111
26069764-2	2012	Patients with congenital NDI bearing mutations in the vasopressin 2 receptor gene, AVPR2, or in the aquaporin-2 gene, AQP2, have a pure NDI phenotype with loss of water but normal conservation of sodium, potassium, chloride and calcium.	Potassium	204-213	aquaporin 2	Homo sapiens	118-122
22650221-4	2012	Although there is a theoretical basis for the use of glucose-insulin-potassium infusion during AMI, lack of outcome efficacy (and inability to reach glycemic targets) in recent randomized trials has resulted in little enthusiasm for this strategy.	Potassium	69-78	insulin	Homo sapiens	61-68
22329368-0	2012	Plasma-membrane hyperpolarization diminishes the cation efflux via Nha1 antiporter and Ena ATPase under potassium-limiting conditions.	Potassium	104-113	Nha1p	Saccharomyces cerevisiae S288C	67-71
22329368-2	2012	Lost potassium is taken up by the Trk1 and Trk2 uptake systems.	Potassium	5-14	Trk1p	Saccharomyces cerevisiae S288C	34-38
22329368-2	2012	Lost potassium is taken up by the Trk1 and Trk2 uptake systems.	Potassium	5-14	Trk2p	Saccharomyces cerevisiae S288C	43-47
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	69-78	Nha1p	Saccharomyces cerevisiae S288C	161-165
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	69-78	Tok1p	Saccharomyces cerevisiae S288C	193-197
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	129-138	Nha1p	Saccharomyces cerevisiae S288C	161-165
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	129-138	Tok1p	Saccharomyces cerevisiae S288C	193-197
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	129-138	Nha1p	Saccharomyces cerevisiae S288C	161-165
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	129-138	Tok1p	Saccharomyces cerevisiae S288C	193-197
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	129-138	Nha1p	Saccharomyces cerevisiae S288C	161-165
22329368-4	2012	A series of experiments with strains lacking various combinations of potassium efflux and uptake systems revealed that all three potassium-exporting systems the Nha1 antiporter, Ena ATPase and Tok1 channel contribute to potassium homeostasis and are active upon potassium limitation in wild-type cells.	Potassium	129-138	Tok1p	Saccharomyces cerevisiae S288C	193-197
22329368-5	2012	In trk1Delta trk2Delta mutants, the potassium efflux via potassium exporters Nha1 and Ena1 is diminished and can be restored either by the expression of TRK1 or deletion of TOK1.	Potassium	36-45	Trk1p	Saccharomyces cerevisiae S288C	3-7
22329368-5	2012	In trk1Delta trk2Delta mutants, the potassium efflux via potassium exporters Nha1 and Ena1 is diminished and can be restored either by the expression of TRK1 or deletion of TOK1.	Potassium	36-45	Nha1p	Saccharomyces cerevisiae S288C	77-81
22329368-5	2012	In trk1Delta trk2Delta mutants, the potassium efflux via potassium exporters Nha1 and Ena1 is diminished and can be restored either by the expression of TRK1 or deletion of TOK1.	Potassium	36-45	Na(+)/Li(+)-exporting P-type ATPase ENA1	Saccharomyces cerevisiae S288C	86-90
22329368-5	2012	In trk1Delta trk2Delta mutants, the potassium efflux via potassium exporters Nha1 and Ena1 is diminished and can be restored either by the expression of TRK1 or deletion of TOK1.	Potassium	36-45	Trk1p	Saccharomyces cerevisiae S288C	153-157
22329368-5	2012	In trk1Delta trk2Delta mutants, the potassium efflux via potassium exporters Nha1 and Ena1 is diminished and can be restored either by the expression of TRK1 or deletion of TOK1.	Potassium	36-45	Tok1p	Saccharomyces cerevisiae S288C	173-177
22950024-0	2012	Adaptation to potassium starvation of wild-type and K(+)-transport mutant (trk1,2) of Saccharomyces cerevisiae: 2-dimensional gel electrophoresis-based proteomic approach.	Potassium	14-23	Trk1p	Saccharomyces cerevisiae S288C	75-81
22407650-7	2012	The potassium carrier mutant trh1 displayed different patterns of root gravitropism and DR5::GUS signal intensity in root apex cells compared with the wild type in response to NH(4)(+).	Potassium	4-13	Potassium transporter family protein	Arabidopsis thaliana	29-33
22250216-1	2012	M1476I, a French Canadian founder mutation of Na+ channel Nav1.4, causes potassium-aggravated myotonia, with cold-induced myotonia as the most distinctive clinical feature.	Potassium	73-82	sodium voltage-gated channel alpha subunit 4	Homo sapiens	58-64
22531785-8	2012	Interestingly, prevention of PFT-induced potassium efflux inhibits the formation of caspase-2 complex, leading to its inactivation, thus resisting apoptosis.	Potassium	41-50	caspase 2	Homo sapiens	84-93
22475983-0	2012	Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate.	Potassium	24-33	coagulation factor II, thrombin	Homo sapiens	92-100
22642439-6	2012	CHPG was also able to induce modulation of M-type potassium current through mGluR1, but not as consistently as glutamate.	Potassium	50-59	glutamate metabotropic receptor 1	Rattus norvegicus	76-82
22632146-5	2012	Furthermore, mRNA and protein levels of transporters of glutamate (GLT-1) and potassium (Kir4.1), functional markers of astrocytes, decreased at about the times that delayed neuronal death occurred.	Potassium	78-87	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	89-95
22586403-2	2012	A reduction of the transient outward potassium current (I(to)) in mammalian heart failure is consistent with a reduced expression of potassium channel interacting protein 2 (KChIP2, a K(V)4 subunit).	Potassium	37-46	potassium voltage-gated channel interacting protein 2	Homo sapiens	133-172
22425651-6	2012	It also down-regulated the expression of Kv1.4 and increased the expression of Kv4.2 and Kv4.3, so it might through regulating the expression of the transient outward potassium current (Ito) to improve the cardiac function.	Potassium	167-176	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	41-46
22425651-6	2012	It also down-regulated the expression of Kv1.4 and increased the expression of Kv4.2 and Kv4.3, so it might through regulating the expression of the transient outward potassium current (Ito) to improve the cardiac function.	Potassium	167-176	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	79-84
22425651-6	2012	It also down-regulated the expression of Kv1.4 and increased the expression of Kv4.2 and Kv4.3, so it might through regulating the expression of the transient outward potassium current (Ito) to improve the cardiac function.	Potassium	167-176	potassium voltage-gated channel subfamily D member 3	Rattus norvegicus	89-94
22366095-3	2012	In VAT, the expression of PCK1, PLIN, ADIPOQ and PPARG was inversely correlated with aldosterone levels; furthermore, PLIN and ADIPOQ gene expression was correlated with potassium levels.	Potassium	170-179	perilipin 1	Homo sapiens	118-122
22366095-3	2012	In VAT, the expression of PCK1, PLIN, ADIPOQ and PPARG was inversely correlated with aldosterone levels; furthermore, PLIN and ADIPOQ gene expression was correlated with potassium levels.	Potassium	170-179	adiponectin, C1Q and collagen domain containing	Homo sapiens	127-133
22512618-1	2012	In our pursuit of developing a novel and potent potassium-competitive acid blocker (P-CAB), we synthesized pyrrole derivatives focusing on compounds with low log D and high ligand-lipophilicity efficiency (LLE) values.	Potassium	48-57	neural proliferation, differentiation and control 1	Homo sapiens	86-89
22586403-2	2012	A reduction of the transient outward potassium current (I(to)) in mammalian heart failure is consistent with a reduced expression of potassium channel interacting protein 2 (KChIP2, a K(V)4 subunit).	Potassium	37-46	potassium voltage-gated channel interacting protein 2	Homo sapiens	174-180
26288050-3	2012	Potential-modulated attenuated total reflectance (PM-ATR) measurements show that the monomeric subpopulation undergoes oxidation/reduction with ks,app = 2 x 10(2) s(-1), independent of Pc orientation.	Potassium	144-146	X-prolyl aminopeptidase 2	Homo sapiens	147-154
26288050-5	2012	For in-plane-oriented Pc aggregates, ks,app = 2 x 10(3) s(-1), whereas for upright Pc aggregates, ks,app = 7 x 10(2) s(-1).	Potassium	37-39	X-prolyl aminopeptidase 2	Homo sapiens	40-47
22087608-7	2012	AM5 infusion also induced significant increases in urine volume (HD 2-fold increment, P&lt;0.05) and urine sodium (2.7-fold increment, P&lt;0.01), potassium (1.7-fold increment, P&lt;0.05) and creatinine (1.4-fold increment, P&lt;0.05) excretion and creatinine clearance (60% increment, P&lt;0.05).	Potassium	147-156	adrenomedullin 5 (putative)	Homo sapiens	0-3
22240917-7	2012	These findings indicate that serum potassium elevation is negatively related to partial agonistic activities for MR, and SM-368229 shows antihypertensive efficacy with minimal effect on serum potassium level, probably due to its partial agonistic property.	Potassium	35-44	nuclear receptor subfamily 3, group C, member 2	Rattus norvegicus	113-115
22155597-11	2012	Co-expression of KCND3/WT + SCN1Bb/R214Q induced a Kv4.3 current (transient outward potassium current, I(to)) 70.6% greater compared with KCND3/WT + SCN1Bb/WT (n = 10-11, P&lt;0.01).	Potassium	84-93	potassium voltage-gated channel subfamily D member 3	Homo sapiens	17-22
22155597-11	2012	Co-expression of KCND3/WT + SCN1Bb/R214Q induced a Kv4.3 current (transient outward potassium current, I(to)) 70.6% greater compared with KCND3/WT + SCN1Bb/WT (n = 10-11, P&lt;0.01).	Potassium	84-93	potassium voltage-gated channel subfamily D member 3	Homo sapiens	51-56
22583083-5	2012	To this end, KCNE1/KCNQ1 was expressed in Xenopus oocytes with and without beta-catenin and the depolarization (up to + 80 mV) induced current (I(Ks)) was determined using the two-electrode voltage clamp.	Potassium	146-148	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	13-18
22583083-6	2012	As a result, beta-catenin enhanced I(Ks) by 30%.	Potassium	37-39	catenin beta 1 L homeolog	Xenopus laevis	13-25
22583083-7	2012	The effect of beta-catenin on I(Ks) was not affected by actinomycin D (10 muM), an inhibitor of transcription, indicating that beta-catenin was not effective as transcription factor.	Potassium	32-34	catenin beta 1 L homeolog	Xenopus laevis	14-26
22583083-10	2012	In conclusion, beta-catenin enhances I(Ks) by increasing the KCNE1/KCNQ1 protein abundance in the cell membrane, an effect requiring vesicle insertion into the cell membrane.	Potassium	39-41	catenin beta 1 L homeolog	Xenopus laevis	15-27
22583083-10	2012	In conclusion, beta-catenin enhances I(Ks) by increasing the KCNE1/KCNQ1 protein abundance in the cell membrane, an effect requiring vesicle insertion into the cell membrane.	Potassium	39-41	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	61-66
22583083-10	2012	In conclusion, beta-catenin enhances I(Ks) by increasing the KCNE1/KCNQ1 protein abundance in the cell membrane, an effect requiring vesicle insertion into the cell membrane.	Potassium	39-41	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	67-72
22539834-1	2012	The channel pore-forming alpha subunit Kv4.2 is a major constituent of A-type (I(A)) potassium currents and a key regulator of neuronal membrane excitability.	Potassium	85-94	potassium voltage-gated channel, Shal-related family, member 2	Mus musculus	39-44
22127737-1	2012	Structural determinants responsible for the substrate preference of the potassium-independent (ASPGA1) and -dependent (ASPGB1) asparaginases from Arabidopsis thaliana have been investigated.	Potassium	72-81	N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein	Arabidopsis thaliana	95-101
22127737-1	2012	Structural determinants responsible for the substrate preference of the potassium-independent (ASPGA1) and -dependent (ASPGB1) asparaginases from Arabidopsis thaliana have been investigated.	Potassium	72-81	N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein	Arabidopsis thaliana	119-125
22469025-6	2012	CONCLUSION: A nonspecific inflammatory response triggered by activation of NK cells upon KIR-HLA interaction could be associated with the pathogenesis of KS.	Potassium	154-156	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	89-92
22471507-1	2012	Here we report the successful synthesis of superconducting potassium-doped few-layer graphene (K-doped FLG) with a transition temperature of 4.5 K, which is 1 order of magnitude higher than that observed in the bulk potassium graphite intercalation compound (GIC) KC(8) (T(c) = 0.39 K).	Potassium	59-68	filaggrin	Homo sapiens	103-106
22415212-0	2012	Influence of methanandamide and CGRP on potassium currents in smooth muscle cells of small mesenteric arteries.	Potassium	40-49	calcitonin-related polypeptide alpha	Rattus norvegicus	32-36
21709053-12	2012	This drug triggers a potassium efflux via a mechanism which does not involve purinergic receptors and generates, in consequence, the activation of caspase-1 and the secretion of IL-1beta.	Potassium	21-30	caspase 1	Mus musculus	147-156
21709053-12	2012	This drug triggers a potassium efflux via a mechanism which does not involve purinergic receptors and generates, in consequence, the activation of caspase-1 and the secretion of IL-1beta.	Potassium	21-30	interleukin 1 beta	Mus musculus	178-186
21538577-2	2012	KSHV encodes a pro-angiogenic viral chemokine receptor (vGPCR) that promotes EC growth in vitro and KS-like tumors in mouse models.	Potassium	0-2	K14	Human gammaherpesvirus 8	56-61
21538577-3	2012	vGPCR is therefore considered a viral oncogene that plays a crucial role in the pathobiology of KS.	Potassium	96-98	K14	Human gammaherpesvirus 8	0-5
22275517-9	2012	Genotype differences in glycinergic mIPSCs were more evident during sustained stimulation by solutions with high potassium levels, suggesting that the estimated size of the readily releasable pool of glycine-containing vesicles was reduced in VGAT(+/-) mice.	Potassium	113-122	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	243-247
22373544-4	2012	We establish the membrane ions" contributions (sodium, potassium, calcium and iron) mediated by water to the antagonism of these drugs at the 5-HT1A receptor.	Potassium	55-64	5-hydroxytryptamine receptor 1A	Homo sapiens	142-157
22373544-6	2012	Our results indicate that potassium, calcium and iron play a key role for the antagonistic activity of drugs at the 5-HT1A receptor.	Potassium	26-35	5-hydroxytryptamine receptor 1A	Homo sapiens	116-131
22305629-5	2012	A high potassium concentration was used to release CGRP from dura mater, isolated TG, and TNC in vitro.	Potassium	7-16	calcitonin-related polypeptide alpha	Rattus norvegicus	51-55
22415212-4	2012	In the present study, the direct influence of the cannabinoid methanandamide and the neuropeptide CGRP on the membrane potassium ion (K(+)) currents of rat mesenteric myocytes was explored.	Potassium	119-128	calcitonin-related polypeptide alpha	Rattus norvegicus	98-102
22323544-2	2012	In this work, we demonstrate that L. interrogans induces NLRP3 inflammasome-dependent secretion of IL-1beta through the alteration of potassium transport in bone marrow-derived macrophages.	Potassium	134-143	interleukin 1 beta	Mus musculus	99-107
23576844-5	2012	Electrochemical parameter of Mb in Mb-GO-Nafion film such as apparent heterogeneous electron transfer rate constant (ks) and formal potential (Eo") were obtained.	Potassium	117-119	myoglobin	Homo sapiens	29-31
22192952-0	2012	Inhibitory effect of tungsten carbide nanoparticles on voltage-gated potassium currents of hippocampal CA1 neurons.	Potassium	69-78	carbonic anhydrase 1	Rattus norvegicus	103-106
22198508-0	2012	Modulation of human cardiac transient outward potassium current by EGFR tyrosine kinase and Src-family kinases.	Potassium	46-55	epidermal growth factor receptor	Homo sapiens	67-71
21316179-2	2012	Because insulin therapy decreases serum potassium levels, which creates potential to precipitate a fatal cardiac arrhythmia in a patient with hypokalemia, the American Diabetes Association (ADA) recommends obtaining a serum potassium level before giving insulin.	Potassium	40-49	insulin	Homo sapiens	8-15
21316179-2	2012	Because insulin therapy decreases serum potassium levels, which creates potential to precipitate a fatal cardiac arrhythmia in a patient with hypokalemia, the American Diabetes Association (ADA) recommends obtaining a serum potassium level before giving insulin.	Potassium	224-233	insulin	Homo sapiens	8-15
21950312-8	2012	A potassium 5.5-5.9mmol/L occurred on &gt;=1 occasion over follow-up in 11 patients (nine on spironolactone) and was predicted by baseline potassium &gt;=5.0mmol/L and eGFR &lt;=45 ml/min/1.73m(2) .	Potassium	2-11	epidermal growth factor receptor	Homo sapiens	168-172
21946656-1	2012	OBJECTIVES: Insulin administration lowers plasma potassium concentration by augmenting intracellular uptake of potassium.	Potassium	49-58	insulin	Homo sapiens	12-19
21946656-1	2012	OBJECTIVES: Insulin administration lowers plasma potassium concentration by augmenting intracellular uptake of potassium.	Potassium	111-120	insulin	Homo sapiens	12-19
22198508-0	2012	Modulation of human cardiac transient outward potassium current by EGFR tyrosine kinase and Src-family kinases.	Potassium	46-55	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	92-95
21946656-3	2012	Some studies suggest that insulin has an antikaliuretic effect although plasma potassium levels were poorly controlled.	Potassium	79-88	insulin	Homo sapiens	26-33
22024150-7	2012	RESULTS: Electrophysiological investigations of KCNQ1/KCNE1 proteins coexpressed with USP2-45 or USP2-69 isoforms and Nedd4-2 in Xenopus laevis oocytes and mammalian cells revealed that both USP2 isoforms counter the Nedd4-2-specific downregulation of I(Ks).	Potassium	254-256	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	54-59
21946656-5	2012	We examined the relation between administered insulin and renal potassium excretion in critically ill patients under computer-assisted glucose and potassium regulation.	Potassium	64-73	insulin	Homo sapiens	46-53
21946656-17	2012	After multivariate analysis correcting for relevant variables (including diuretics, pH, potassium levels and renal sodium excretion), insulin administration was independently and positively associated with renal potassium excretion.	Potassium	88-97	insulin	Homo sapiens	134-141
21946656-17	2012	After multivariate analysis correcting for relevant variables (including diuretics, pH, potassium levels and renal sodium excretion), insulin administration was independently and positively associated with renal potassium excretion.	Potassium	212-221	insulin	Homo sapiens	134-141
21946656-20	2012	CONCLUSION: Insulin administration is associated with an increase in the renal potassium excretion in critically ill patients.	Potassium	79-88	insulin	Homo sapiens	12-19
22438021-0	2012	Ion exchangers NHX1 and NHX2 mediate active potassium uptake into vacuoles to regulate cell turgor and stomatal function in Arabidopsis.	Potassium	44-53	Na+/H+ exchanger 1	Arabidopsis thaliana	15-19
21725920-0	2012	Nrf2 and Sp family synergistically enhance the expression of ion transporters in potassium-depleted conditions.	Potassium	81-90	NFE2 like bZIP transcription factor 2	Homo sapiens	0-4
22147752-1	2012	TASK-3 (KCNK9) tandem-pore potassium channels provide a volatile anesthetic-activated and Galpha(q) protein- and acidic pH-inhibited potassium conductance important in neuronal excitability.	Potassium	27-36	potassium two pore domain channel subfamily K member 9	Rattus norvegicus	8-13
22147752-1	2012	TASK-3 (KCNK9) tandem-pore potassium channels provide a volatile anesthetic-activated and Galpha(q) protein- and acidic pH-inhibited potassium conductance important in neuronal excitability.	Potassium	27-36	G protein subunit alpha q	Rattus norvegicus	90-99
22214817-4	2012	However, when grown under conditions that induce stress on the plasma membrane protonmotive force (PMF), such as high external potassium to reduce the electrical gradient or high external pH to reduce the proton chemical gradient, aha2 mutant plants show a growth retardation compared with wild-type plants.	Potassium	127-136	H[+]-ATPase 2	Arabidopsis thaliana	231-235
22214817-7	2012	In addition, genome-wide gene expression profiling revealed the up-regulation of potassium transporters in aha2 mutants, indicating, as predicted, a close link between the PMF and potassium uptake at the plasma membrane.	Potassium	81-90	H[+]-ATPase 2	Arabidopsis thaliana	107-111
22438021-0	2012	Ion exchangers NHX1 and NHX2 mediate active potassium uptake into vacuoles to regulate cell turgor and stomatal function in Arabidopsis.	Potassium	44-53	sodium hydrogen exchanger 2	Arabidopsis thaliana	24-28
22250904-4	2012	Other functions of brain AQP4 involve potassium uptake and release by astrocytes, migration of glial cells, glial scarring, and astrocyte-to-astrocyte cell communication.	Potassium	38-47	aquaporin 4	Homo sapiens	25-29
22357867-6	2012	We report that in cultured cerebellar granule neurons induced to die by low potassium treatment and in Abeta-treated cortical neurons, Mecp2-e2 expression is upregulated whereas expression of the Mecp2-e1 isoform is downregulated.	Potassium	76-85	methyl CpG binding protein 2	Mus musculus	196-204
22367544-5	2012	Klf15 transcriptionally controls rhythmic expression of Kv channel-interacting protein 2 (KChIP2), a critical subunit required for generating the transient outward potassium current.	Potassium	164-173	Kruppel-like factor 15	Mus musculus	0-5
22367544-5	2012	Klf15 transcriptionally controls rhythmic expression of Kv channel-interacting protein 2 (KChIP2), a critical subunit required for generating the transient outward potassium current.	Potassium	164-173	Kv channel-interacting protein 2	Mus musculus	56-88
22367544-5	2012	Klf15 transcriptionally controls rhythmic expression of Kv channel-interacting protein 2 (KChIP2), a critical subunit required for generating the transient outward potassium current.	Potassium	164-173	Kv channel-interacting protein 2	Mus musculus	90-96
22100668-7	2012	The SNP KCNE1 D85N (rs1805128), known to modulate an important potassium current in the heart, predicted diLQTS with an odds ratio of 9.0 (95% confidence interval, 3.5-22.9).	Potassium	63-72	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	8-13
22213115-7	2012	MAIN METHODS: The NOP receptor activity was evaluated by G-protein coupled inwardly rectifying potassium (GIRK) currents in rat vlPAG slices, and by inhibition of cAMP accumulation in HEK293 cells expressing NOP receptors or co-expressing NOP and MOP receptors.	Potassium	95-104	prepronociceptin	Homo sapiens	18-21
22298604-5	2012	RESULTS: In the group of patients who stopped the PLD  (ie, continued the PID ), mean serum potassium levels increased 0.19 mEq/L (range -0.9 to 1.8 mEq/L).	Potassium	92-101	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	50-53
22298604-5	2012	RESULTS: In the group of patients who stopped the PLD  (ie, continued the PID ), mean serum potassium levels increased 0.19 mEq/L (range -0.9 to 1.8 mEq/L).	Potassium	92-101	metastasis associated 1 family member 2	Homo sapiens	74-77
22298604-6	2012	After discontinuation of the PLD , serum potassium levels increased in 91 (59%) patients.	Potassium	41-50	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	29-32
22298604-8	2012	In the group of patients who stopped the PID  (ie, continued the PLD ), mean serum potassium levels decreased 0.40 mEq/L (range -2.6 to 0.7 mEq/L).	Potassium	83-92	metastasis associated 1 family member 2	Homo sapiens	41-44
22298604-8	2012	In the group of patients who stopped the PID  (ie, continued the PLD ), mean serum potassium levels decreased 0.40 mEq/L (range -2.6 to 0.7 mEq/L).	Potassium	83-92	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	65-68
22298604-9	2012	Serum potassium levels decreased in 61 (70%) patients after discontinuation of the PID .	Potassium	6-15	metastasis associated 1 family member 2	Homo sapiens	83-86
22340148-3	2012	RESULTS: Significant correlations were found between GAF scores and energy (kilocalories), carbohydrates, fibre, total fat, linoleic acid, riboflavin, niacin, folate, vitamin B6, vitamin B12, pantothenic acid, calcium, phosphorus, potassium, and iron (all P values &lt; 0.05), as well as magnesium (r = 0.41, P &lt; 0.001) and zinc (r = 0.35, P &lt; 0.001).	Potassium	231-240	fibroblast growth factor 9	Homo sapiens	53-56
22038261-1	2012	The renal outer medullary potassium channel (ROMK) is an adenosine triphosphate-sensitive inward-rectifier potassium channel (Kir1.1 or KCNJ1) highly expressed in the cortical and medullary thick ascending limbs (TAL), connecting segment (CNT) and cortical collecting duct (CCD) in the mammalian kidney, where it serves to recycle potassium (K(+)) across the apical membrane in TAL and to secrete K(+) in the CNT and CCD.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	136-141
22184322-0	2012	Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake.	Potassium	102-111	cytochrome P450, family 2, subfamily c, polypeptide 23	Mus musculus	0-7
22038256-0	2012	Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport.	Potassium	87-96	serum/glucocorticoid regulated kinase 1	Homo sapiens	0-44
22038261-1	2012	The renal outer medullary potassium channel (ROMK) is an adenosine triphosphate-sensitive inward-rectifier potassium channel (Kir1.1 or KCNJ1) highly expressed in the cortical and medullary thick ascending limbs (TAL), connecting segment (CNT) and cortical collecting duct (CCD) in the mammalian kidney, where it serves to recycle potassium (K(+)) across the apical membrane in TAL and to secrete K(+) in the CNT and CCD.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	45-49
22038261-1	2012	The renal outer medullary potassium channel (ROMK) is an adenosine triphosphate-sensitive inward-rectifier potassium channel (Kir1.1 or KCNJ1) highly expressed in the cortical and medullary thick ascending limbs (TAL), connecting segment (CNT) and cortical collecting duct (CCD) in the mammalian kidney, where it serves to recycle potassium (K(+)) across the apical membrane in TAL and to secrete K(+) in the CNT and CCD.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	57-132
21988371-5	2012	BDNF(+/-) mice also had a potentiated increase in dopamine levels following potassium (120 mM)-stimulation (10-fold) relative to wildtype controls (6-fold).	Potassium	76-85	brain derived neurotrophic factor	Mus musculus	0-4
21845430-1	2012	Hypokalemic periodic paralysis (HypoPP) is an autosomal dominant disorder characterized by periodic attacks of muscle weakness associated with a decrease in the serum potassium level.	Potassium	167-176	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	32-38
22303293-1	2012	The Patchliner  temperature-controlled automated patch clamp system was evaluated for testing drug effects on potassium currents through human ether-a-go-go related gene (hERG) channels expressed in Chinese hamster ovary cells at 35-37 C. IC(50) values for a set of reference drugs were compared with those obtained using the conventional voltage clamp technique.	Potassium	110-119	ETS transcription factor ERG	Homo sapiens	171-175
21863227-4	2012	The aim of this study was to determine whether the increased abundance of sodium:potassium:chloride (Na(+):K(+):2Cl(-)) co-transporter (NKCC2) leads to enhanced sodium uptake by the TAL.	Potassium	81-90	solute carrier family 12 member 1	Rattus norvegicus	136-141
22149452-7	2012	RESULTS: AQP2 excretion increased during potassium supplementation, and free water clearance fell.	Potassium	41-50	aquaporin 2	Homo sapiens	9-13
22183055-8	2012	Consistent with the expected effects of reducing a major neuronal v-SNARE, glutamate-selective, microelectrode array (MEA) measurements in specific hippocampal subregions of VAMP2(+/-) mice showed significant reductions in potassium-evoked glutamate release.	Potassium	223-232	vesicle-associated membrane protein 2	Mus musculus	174-179
22084095-5	2012	The inhibitory effect of SP was found exclusively in neurons expressing acid-sensing ion channel 3, where SP enhances M-channel-like potassium currents through the NK1 receptor in a G protein-independent but tyrosine kinase-dependent manner.	Potassium	133-142	tachykinin 1	Mus musculus	25-27
22095730-4	2012	METHODS AND RESULTS: We characterized the effects of A341V on the I(Ks) macromolecular channel complex in transfected Chinese hamster ovary cells and found a dominant-negative suppression of cAMP-dependent Yotiao-mediated I(Ks) upregulation on top of a dominant-negative reduction in basal current.	Potassium	68-70	A-kinase anchoring protein 9	Homo sapiens	206-212
22095730-6	2012	Western blot analysis showed reduced phosphorylation of KCNQ1 at S27, even for heterozygous A341V, suggesting that phosphorylation defects in some (mutant) KCNQ1 subunits can completely suppress I(Ks) upregulation.	Potassium	197-199	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	56-61
22095730-6	2012	Western blot analysis showed reduced phosphorylation of KCNQ1 at S27, even for heterozygous A341V, suggesting that phosphorylation defects in some (mutant) KCNQ1 subunits can completely suppress I(Ks) upregulation.	Potassium	197-199	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	156-161
22095730-9	2012	CONCLUSIONS: Our results indicate the involvement of the KCNQ1-S6 region at/or around A341 in cAMP-dependent stimulation of I(Ks), a process that is under strong dominant-negative control, suggesting that tetrameric KCNQ1 phosphorylation is required.	Potassium	126-128	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	57-62
22095730-9	2012	CONCLUSIONS: Our results indicate the involvement of the KCNQ1-S6 region at/or around A341 in cAMP-dependent stimulation of I(Ks), a process that is under strong dominant-negative control, suggesting that tetrameric KCNQ1 phosphorylation is required.	Potassium	126-128	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	216-221
22084095-5	2012	The inhibitory effect of SP was found exclusively in neurons expressing acid-sensing ion channel 3, where SP enhances M-channel-like potassium currents through the NK1 receptor in a G protein-independent but tyrosine kinase-dependent manner.	Potassium	133-142	acid-sensing (proton-gated) ion channel 3	Mus musculus	72-98
22084095-5	2012	The inhibitory effect of SP was found exclusively in neurons expressing acid-sensing ion channel 3, where SP enhances M-channel-like potassium currents through the NK1 receptor in a G protein-independent but tyrosine kinase-dependent manner.	Potassium	133-142	tachykinin 1	Mus musculus	106-108
22084095-5	2012	The inhibitory effect of SP was found exclusively in neurons expressing acid-sensing ion channel 3, where SP enhances M-channel-like potassium currents through the NK1 receptor in a G protein-independent but tyrosine kinase-dependent manner.	Potassium	133-142	tachykinin receptor 1	Mus musculus	164-176
22136504-9	2012	Serum potassium levels were significantly lower in ABV than in TDF treated patients.	Potassium	6-15	sex determining region Y	Homo sapiens	63-66
22896926-2	2012	Connexin 26 expression in the lateral wall may play a role in acquired hearing loss by maintaining the endocochlear potential and potassium concentration in the endolymph.	Potassium	130-139	gap junction protein, beta 2	Rattus norvegicus	0-11
21030184-5	2012	Treatment with norepinephrine, sodium bicarbonate, and insulin improved both the hemodynamic situation and the serum potassium with subsequent regaining pacemaker actions even before additional hemodialysis normalized the potassium level.	Potassium	117-126	insulin	Homo sapiens	55-62
21030184-5	2012	Treatment with norepinephrine, sodium bicarbonate, and insulin improved both the hemodynamic situation and the serum potassium with subsequent regaining pacemaker actions even before additional hemodialysis normalized the potassium level.	Potassium	222-231	insulin	Homo sapiens	55-62
22038828-0	2012	Systemic administration of anti-NGF increases A-type potassium currents and decreases pancreatic nociceptor excitability in a rat model of chronic pancreatitis.	Potassium	53-62	nerve growth factor	Rattus norvegicus	32-35
21922321-8	2012	Arginine-stimulated (p = 0.02) insulin secretion was reduced in vivo, which was further reflected by a reduction of glucose- and potassium-stimulated insulin secretion (p = 0.002 and p = 0.04, respectively) in human islets in vitro.	Potassium	129-138	insulin	Homo sapiens	150-157
21711166-5	2012	Daily potassium air concentrations were associated with significant decreases in DBP (-0.0447 mmHg/ng/m(3) +- 0.0132, p = 0.0016, lag day 0) among participants compliant with the personal monitoring protocol.	Potassium	6-15	D-box binding PAR bZIP transcription factor	Homo sapiens	81-84
22761619-4	2012	Therefore, we tested the hypothesis that IGF-1 and PI3K/Akt signaling, independently, decrease sarcolemmal potassium currents in cardiac myocytes of neonatal rats.	Potassium	107-116	insulin-like growth factor 1	Rattus norvegicus	41-46
22761619-4	2012	Therefore, we tested the hypothesis that IGF-1 and PI3K/Akt signaling, independently, decrease sarcolemmal potassium currents in cardiac myocytes of neonatal rats.	Potassium	107-116	AKT serine/threonine kinase 1	Rattus norvegicus	56-59
22496969-5	2012	Univariate regressions showed that changes in urinary sodium/potassium ratio (beta = 1.99) and plasma renin activity (beta = -15.78) and percent change in plasma nitrite after hyperemia were associated with SBP changes at week one (all P &lt; 0.05).	Potassium	61-70	selenium binding protein 1	Homo sapiens	207-210
21976771-12	2012	The conclusion is that both AtCHX21 and AtCHX23 act in potassium homeostasis within the female gametophyte and this is discussed in terms of the diversification of gene sequence and function within the CHX gene family.	Potassium	55-64	cation/H+ exchanger 21	Arabidopsis thaliana	28-35
21976771-12	2012	The conclusion is that both AtCHX21 and AtCHX23 act in potassium homeostasis within the female gametophyte and this is discussed in terms of the diversification of gene sequence and function within the CHX gene family.	Potassium	55-64	cation/H+ exchanger 23	Arabidopsis thaliana	40-47
22190306-1	2012	BACKGROUND: Kv7.5 (KCNQ5) channels conduct M-type potassium currents in the brain, are expressed in skeletal muscle, and contribute to vascular muscle tone.	Potassium	50-59	potassium voltage-gated channel subfamily Q member 5	Homo sapiens	12-17
22079268-1	2012	Inwardly rectifying potassium (Kir) channels are essential for maintaining normal potassium homeostasis and the resting membrane potential.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
22190306-1	2012	BACKGROUND: Kv7.5 (KCNQ5) channels conduct M-type potassium currents in the brain, are expressed in skeletal muscle, and contribute to vascular muscle tone.	Potassium	50-59	potassium voltage-gated channel subfamily Q member 5	Homo sapiens	19-24
21792084-6	2012	Likewise, Akt inhibition also reduces both glucose-stimulated and potassium depolarization-stimulated insulin secretion from INS-1 cells.	Potassium	66-75	AKT serine/threonine kinase 1	Rattus norvegicus	10-13
22156587-3	2012	METHODS: We studied predialysis mortality and slopes of estimated glomerular filtration rate, eGFR) associated with serum potassium in 1,227 males with CKD.	Potassium	122-131	epidermal growth factor receptor	Homo sapiens	94-98
22156587-6	2012	Hypokalemia was associated with loss of kidney function independent of race: a 1 mEq/l lower potassium was associated with an adjusted difference in slopes of eGFR of -0.13 ml/min/1.73 m(2)/year (95% CI: -0.20 to -0.07), p &lt; 0.001.	Potassium	93-102	epidermal growth factor receptor	Homo sapiens	159-163
21951015-9	2012	Lastly, we examined a potential role for hypokalemia as a contributory factor to the patient"s lethal arrhythmia by possible low-potassium-induced degradation of WT HERG and haplo-insufficiency of G816V HERG.	Potassium	129-138	potassium voltage-gated channel subfamily H member 2	Homo sapiens	165-169
21951015-9	2012	Lastly, we examined a potential role for hypokalemia as a contributory factor to the patient"s lethal arrhythmia by possible low-potassium-induced degradation of WT HERG and haplo-insufficiency of G816V HERG.	Potassium	129-138	potassium voltage-gated channel subfamily H member 2	Homo sapiens	203-207
22737060-6	2012	In contrast to the prevailing view, we show that regulation of the main potassium transport systems (Trk1,2 and Nha1) in the plasma membrane is not sufficient to achieve homeostasis.	Potassium	72-81	Trk1p	Saccharomyces cerevisiae S288C	101-105
22737060-6	2012	In contrast to the prevailing view, we show that regulation of the main potassium transport systems (Trk1,2 and Nha1) in the plasma membrane is not sufficient to achieve homeostasis.	Potassium	72-81	Nha1p	Saccharomyces cerevisiae S288C	112-116
21792084-6	2012	Likewise, Akt inhibition also reduces both glucose-stimulated and potassium depolarization-stimulated insulin secretion from INS-1 cells.	Potassium	66-75	insulin 1	Rattus norvegicus	125-130
23251508-3	2012	Marked potassium release occurred within 5 min and hemolysis within 20 min in human red blood cells (RBC) exposed to venom or purified venom porin.	Potassium	7-16	voltage dependent anion channel 1	Homo sapiens	141-146
23251508-6	2012	Recognizing that porin assembly can be inhibited by zinc, we found that zinc gluconate inhibited potassium efflux from RBC exposed to total venom or purified porin, and prolonged survival time in mice following venom injection.	Potassium	97-106	voltage dependent anion channel 1	Homo sapiens	17-22
23251508-6	2012	Recognizing that porin assembly can be inhibited by zinc, we found that zinc gluconate inhibited potassium efflux from RBC exposed to total venom or purified porin, and prolonged survival time in mice following venom injection.	Potassium	97-106	voltage dependent anion channel 1	Homo sapiens	158-163
23133669-2	2012	Unlike most voltage-gated K(+)-channels, hERG shows a low elementary conductance at physiological voltage and potassium concentration.	Potassium	110-119	ETS transcription factor ERG	Homo sapiens	41-45
23110108-3	2012	Consistent with these data, voltage-independent and TRAM-34 sensitive potassium currents imputable to the KCa3.1 channel were recorded in the murine GL261 cell line and several primary human glioblastoma cells lines.	Potassium	70-79	toll-like receptor adaptor molecule 2	Mus musculus	52-56
23071770-3	2012	In particular, the interplay intracellular chloride accumulation via the GABA(A) receptor and extracellular potassium accumulation via the K/Cl co-transporter KCC2 in promoting GABA(A)-mediated excitation is complex.	Potassium	108-117	solute carrier family 12 member 5	Homo sapiens	159-163
23115641-1	2012	Kv7.2 and Kv7.3 are the main components of the neuronal voltage-dependent M-current, which is a subthreshold potassium conductance that exerts an important control on neuronal excitability.	Potassium	109-118	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	0-5
23115641-1	2012	Kv7.2 and Kv7.3 are the main components of the neuronal voltage-dependent M-current, which is a subthreshold potassium conductance that exerts an important control on neuronal excitability.	Potassium	109-118	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	10-15
23110108-3	2012	Consistent with these data, voltage-independent and TRAM-34 sensitive potassium currents imputable to the KCa3.1 channel were recorded in the murine GL261 cell line and several primary human glioblastoma cells lines.	Potassium	70-79	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	106-112
22393394-7	2012	CONCLUSION/SIGNIFICANCE: Our results identify a mechanism mediated by Reactive Oxygen Species (ROS) production and potassium efflux as the two danger signals that link JEV infection to caspase-1 activation resulting in subsequent IL-1beta and IL-18 maturation.	Potassium	115-124	caspase 1	Homo sapiens	185-194
22724017-12	2012	In addition, both of the KS patients had a mutation in CHD7 (p.Q51X) or FGFR1 (c.91+2T&gt;A).	Potassium	25-27	chromodomain helicase DNA binding protein 7	Homo sapiens	55-59
22724017-12	2012	In addition, both of the KS patients had a mutation in CHD7 (p.Q51X) or FGFR1 (c.91+2T&gt;A).	Potassium	25-27	fibroblast growth factor receptor 1	Homo sapiens	72-77
22768222-5	2012	We show that activation of NALP3 depends on phagocytosis of dying cells, ATP release through pannexin-1 channels of dying autophagic cells, P(2)X(7) purinergic receptor activation, and on consequent potassium efflux.	Potassium	199-208	NLR family, pyrin domain containing 3	Mus musculus	27-32
22606244-1	2012	Some inflammatory stimuli trigger activation of the NLRP3 inflammasome by inducing efflux of cellular potassium.	Potassium	102-111	NLR family, pyrin domain containing 3	Mus musculus	52-57
22606244-9	2012	Despite the inability of these inhibitors to trigger efflux of intracellular potassium, the addition of high extracellular potassium suppressed activation of the NLRP3 inflammasome.	Potassium	123-132	NLR family, pyrin domain containing 3	Mus musculus	162-167
22606244-13	2012	For agents that inhibit translation through mechanisms that do not involve loss of potassium, high extracellular potassium suppresses IL-1ss processing through a mechanism that remains undefined.	Potassium	113-122	interleukin 1 complex	Mus musculus	134-138
22493723-2	2012	Potassium kinetics can be modulated by aquaporin-4 (AQP4), the essential water channel for astrocyte water permeability regulation.	Potassium	0-9	aquaporin 4	Rattus norvegicus	39-50
22493723-2	2012	Potassium kinetics can be modulated by aquaporin-4 (AQP4), the essential water channel for astrocyte water permeability regulation.	Potassium	0-9	aquaporin 4	Rattus norvegicus	52-56
22493723-11	2012	In conclusion, we find that elevation of extracellular potassium regulates AQP4 and astrocyte water permeability via intracellular signaling involving cAMP.	Potassium	55-64	aquaporin 4	Rattus norvegicus	75-79
23037694-5	2012	We previously showed that valinomycin, a potassium selective ionophore, also caused release of cytochrome c from mitochondria without inducing PT.	Potassium	41-50	cytochrome c, somatic	Homo sapiens	95-107
21455705-5	2011	The study showed that the combination of salt stress and potassium-deficient stress more significantly decreased nitrate uptake, plant growth, the activities of nitrate reductase, glutamate dehydrogenase, glutamate synthase, urease, glutamic-pyruvic transaminase, glutamic-oxaloace transaminase, sucrose-phosphate synthase, phosphoenolpyruvate carboxylase, and the synthesis of free amino acids, chlorophyll, and protein than those of each individual stress, respectively.	Potassium	57-66	nitrate reductase [NADH] 1	Zea mays	161-178
22109556-4	2011	Using computational modeling, we show that intrinsic potassium currents (I(A) and I(SK)) in projection neurons may combine with extrinsic inhibition from local interneurons to implement a dual latency code for both pheromone identity and intensity.	Potassium	53-62	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	82-87
21455705-5	2011	The study showed that the combination of salt stress and potassium-deficient stress more significantly decreased nitrate uptake, plant growth, the activities of nitrate reductase, glutamate dehydrogenase, glutamate synthase, urease, glutamic-pyruvic transaminase, glutamic-oxaloace transaminase, sucrose-phosphate synthase, phosphoenolpyruvate carboxylase, and the synthesis of free amino acids, chlorophyll, and protein than those of each individual stress, respectively.	Potassium	57-66	glutamic dehydrogenase1	Zea mays	180-203
21455705-5	2011	The study showed that the combination of salt stress and potassium-deficient stress more significantly decreased nitrate uptake, plant growth, the activities of nitrate reductase, glutamate dehydrogenase, glutamate synthase, urease, glutamic-pyruvic transaminase, glutamic-oxaloace transaminase, sucrose-phosphate synthase, phosphoenolpyruvate carboxylase, and the synthesis of free amino acids, chlorophyll, and protein than those of each individual stress, respectively.	Potassium	57-66	MLO-like protein 4	Zea mays	324-355
21595652-6	2011	KEY RESULTS: The potassium pulse produced a pH(i) increase of 0.18 +- 0.006 (n= 5), which was reduced by the a-L3 antibody (0.016 +- 0.019).	Potassium	17-26	glucose-6-phosphate isomerase	Homo sapiens	44-49
21945676-0	2011	Blocking of sodium and potassium ion-dependent adenosine triphosphatase-alpha1 with ouabain and vanadate suppresses cell-cell fusion during RANKL-mediated osteoclastogenesis.	Potassium	23-32	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	140-145
21538466-3	2011	We investigated whether pathogenic factors of HE, glutamine (Gln) and/or ammonia, induce alterations in the expression of glial potassium channels (Kir4.1, Kir2.1) and Na(+) -K(+) -2Cl(-) cotransporter-1 (NKCC1) in rat cerebral cortex and cultured rat cortical astrocytes and whether these alterations have consequences for potassium efflux and astrocytic swelling.	Potassium	128-137	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	148-154
21744071-5	2011	The effect of intracellular Ang II on action potential duration was related to the inhibition of potassium conductance through PKC activation because Bis-1 (360 nM), a selective PKC inhibitor, abolished the effect of the peptide.	Potassium	97-106	angiotensinogen	Homo sapiens	28-34
21895724-0	2011	A dual mechanism for I(Ks) current reduction by the pathogenic mutation KCNQ1-S277L.	Potassium	23-25	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	72-77
21895724-1	2011	BACKGROUND: The hereditary long QT syndrome is characterized by prolonged ventricular repolarization that can be caused by mutations to the KCNQ1 gene, which encodes the alpha subunits of the cardiac potassium channel complex that carries the I(Ks) current (the beta subunits are encoded by KCNE1).	Potassium	245-247	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	140-145
21895724-1	2011	BACKGROUND: The hereditary long QT syndrome is characterized by prolonged ventricular repolarization that can be caused by mutations to the KCNQ1 gene, which encodes the alpha subunits of the cardiac potassium channel complex that carries the I(Ks) current (the beta subunits are encoded by KCNE1).	Potassium	245-247	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	291-296
21895724-9	2011	CONCLUSION: The KCNQ1-S277L mutation causes biophysical defects that result in dominant-negative reduction in KCNQ1 and I(Ks) current density, and a trafficking defect that results in reduced surface expression, both without affecting HERG/I(Kr) .	Potassium	122-124	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	16-21
21978672-1	2011	A known side-activity of the oral potassium-sparing diuretic drug amiloride is inhibition of the enzyme urokinase-type plasminogen activator (uPA, K(i)=7 muM), a promising anticancer target.	Potassium	34-43	plasminogen activator, urokinase	Homo sapiens	104-140
21978672-1	2011	A known side-activity of the oral potassium-sparing diuretic drug amiloride is inhibition of the enzyme urokinase-type plasminogen activator (uPA, K(i)=7 muM), a promising anticancer target.	Potassium	34-43	plasminogen activator, urokinase	Homo sapiens	142-145
22078307-6	2011	RESULTS: Here, we reveal that the cagA gene displays strong signatures of positive selection in bacteria isolated from amerindian populations, using the Ka/Ks ratio.	Potassium	156-158	S100 calcium binding protein A8	Homo sapiens	34-38
22057188-2	2011	We identified NCKX4, a potassium-dependent Na(+)/Ca(2+) exchanger, as being necessary for rapid response termination and proper adaptation of vertebrate olfactory sensory neurons (OSNs).	Potassium	23-32	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	Mus musculus	14-19
22074108-8	2011	Similarly, expression of apoB mRNA and protein was lower in pHBV1.3 transfected HepG2 cells than in pBlue-ks transfected HepG2 cells.	Potassium	106-108	apolipoprotein B	Homo sapiens	25-29
21997206-10	2011	Together, these results demonstrate that extracellular potassium generated by neuronal activity modulates Cx30-mediated gap junctional communication between glomerular astrocytes, indicating that strong neuroglial interactions take place at this first relay of olfactory information processing.	Potassium	55-64	gap junction protein, beta 6	Mus musculus	106-110
21075579-11	2011	Once an urgent situation has been handled with intravenous push of a 10% calcium salt, short-term measures should be started with agents that cause a transcellular shift of potassium, namely, insulin with glucose, beta2-agonist, and NaHCO(3).	Potassium	173-182	insulin	Homo sapiens	192-199
21791623-10	2011	In summary, GPER activation relaxes coronary artery smooth muscle by increasing potassium efflux via BK(Ca) channels and requires an intact cellular signaling mechanism.	Potassium	80-89	G protein-coupled estrogen receptor 1	Homo sapiens	12-16
22057188-2	2011	We identified NCKX4, a potassium-dependent Na(+)/Ca(2+) exchanger, as being necessary for rapid response termination and proper adaptation of vertebrate olfactory sensory neurons (OSNs).	Potassium	23-32	nascent polypeptide associated complex subunit alpha 2	Homo sapiens	43-55
22009997-15	2011	CONCLUSIONS: An intravenous infusion including a dextrose:insulin ratio of 3.3:1, compared with a higher ratio, results in less hyperglycemia and appears to be as effective in decreasing potassium concentrations in newborns.	Potassium	187-196	insulin	Homo sapiens	58-65
21855134-1	2011	A 4-amino-naphthalimide derived fluorophore with a triazacryptand moiety ligand was synthesized as a potassium ion (K(+)) sensor (KS1).	Potassium	101-110	zinc finger protein 382	Homo sapiens	130-133
21855134-8	2011	KS1 was used to monitor K(+) efflux stimulated by adenosine-5"-triphosphate (ATP), amphotericin, and a mixture of nigericin, bumetanide and ouabain, demonstrating application of this material as an intracellular potassium ion sensor.	Potassium	212-221	zinc finger protein 382	Homo sapiens	0-3
21908160-11	2011	We also noted that mineralocorticoid receptor inhibition prevented pregnancy-induced decrease in transient outward potassium current.	Potassium	115-124	nuclear receptor subfamily 3, group C, member 2	Rattus norvegicus	19-45
21880468-0	2011	Progressive, potassium-sensitive epileptiform activity in hippocampal area CA3 of pilocarpine-treated rats with recurrent seizures.	Potassium	13-22	carbonic anhydrase 3	Rattus norvegicus	75-78
21778142-0	2011	Voltage-gated potassium currents are targets of diurnal changes in estradiol feedback regulation and kisspeptin action on gonadotropin-releasing hormone neurons in mice.	Potassium	14-23	KiSS-1 metastasis-suppressor	Mus musculus	101-111
21778142-0	2011	Voltage-gated potassium currents are targets of diurnal changes in estradiol feedback regulation and kisspeptin action on gonadotropin-releasing hormone neurons in mice.	Potassium	14-23	gonadotropin releasing hormone 1	Mus musculus	122-152
22042987-6	2011	We found that Ci-KCNQ1 alone could be expressed in Xenopus laevis oocytes and produced a voltage-dependent potassium current, but that Ci-KCNQ1 was not properly modulated by KCNE1 and totally unaffected by coexpression of KCNE3.	Potassium	107-116	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	17-22
21855088-3	2011	We describe a patient with HypoPP who had a high serum potassium concentration after recovery from a recent paralysis, which complicated the correct diagnosis.	Potassium	55-64	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	27-33
21888984-1	2011	INTRODUCTION: Measurement of drug-induced inhibition of potassium current flow through the hERG channel is used to determine potency at the channel, which is used as an in vitro risk assessment for QTc interval prolongation in vivo.	Potassium	56-65	ETS transcription factor ERG	Homo sapiens	91-95
22260022-6	2011	The efficacy in HT-29 cells with high HERG potassium expression level is less potent than that in A549 cells with low expression level.	Potassium	43-52	potassium voltage-gated channel subfamily H member 2	Homo sapiens	38-42
21903939-10	2011	CONCLUSIONS: We propose that HCN3 together with other members of the HCN channel family confer a depolarizing background current that regulates ventricular resting potential and counteracts the action of hyperpolarizing potassium currents in late repolarization.	Potassium	220-229	hyperpolarization-activated, cyclic nucleotide-gated K+ 3	Mus musculus	29-33
21781976-3	2011	Important steps in this process are the production of EETs in the astrocyte and the release of potassium, via two potassium channels (BK and KIR), into the perivascular space.	Potassium	95-104	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	141-144
21921144-6	2011	iGFR and eGFR had similar strengths of association with hyperkalemia/potassium level and with metabolic acidosis/bicarbonate level.	Potassium	69-78	insulin like growth factor 1 receptor	Homo sapiens	0-4
23256274-5	2011	The activation of the nAChR causes a twisting motion of the receptor, which opens a gate allowing for the passage of sodium, potassium, and calcium cations through the cell membrane.	Potassium	125-134	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	22-27
23346606-3	2011	Intensive insulin therapy is defined as an intravenous infusion of insulin and glucose with or without potassium.	Potassium	103-112	insulin	Homo sapiens	10-17
21819957-9	2011	Activating PTEN in these cancers may yield a new treatment strategy for PEL, KS, and similar PTEN wild-type lymphomas.	Potassium	77-79	phosphatase and tensin homolog	Homo sapiens	11-15
21553247-0	2011	BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons.	Potassium	56-65	signal-regulatory protein alpha	Rattus norvegicus	0-3
21553247-0	2011	BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons.	Potassium	56-65	signal-regulatory protein alpha	Rattus norvegicus	4-10
21553247-0	2011	BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons.	Potassium	56-65	brain-derived neurotrophic factor	Rattus norvegicus	44-48
21553247-3	2011	In this article, we have studied the role of BIT/SHPS-1 in the antiapoptotic function of BDNF on low potassium (LK)-induced cell death of cultured CGNs which is an in vitro model system of neuronal apoptosis during brain development.	Potassium	101-110	signal-regulatory protein alpha	Rattus norvegicus	45-48
21553247-3	2011	In this article, we have studied the role of BIT/SHPS-1 in the antiapoptotic function of BDNF on low potassium (LK)-induced cell death of cultured CGNs which is an in vitro model system of neuronal apoptosis during brain development.	Potassium	101-110	brain-derived neurotrophic factor	Rattus norvegicus	89-93
20549616-0	2011	The inhibitory effects of nano-Ag on voltage-gated potassium currents of hippocampal CA1 neurons.	Potassium	51-60	carbonic anhydrase 1	Homo sapiens	85-88
20549616-3	2011	The aim of this study was to investigate the actions of silver nano-particles (nano-Ag) on voltage-activated potassium currents in hippocampal CA1 neurons using whole cell patch-clamp technique.	Potassium	109-118	carbonic anhydrase 1	Homo sapiens	143-146
21699843-0	2011	Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis.	Potassium	33-35	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	52-57
21699843-0	2011	Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis.	Potassium	33-35	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	58-63
21699843-1	2011	BACKGROUND: The slow-activating cardiac repolarization K(+) current (I(Ks)), generated by the KCNQ1-KCNE1 potassium channel complex, is controlled via sympathetic and parasympathetic regulation in vivo.	Potassium	71-73	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	94-99
21699843-1	2011	BACKGROUND: The slow-activating cardiac repolarization K(+) current (I(Ks)), generated by the KCNQ1-KCNE1 potassium channel complex, is controlled via sympathetic and parasympathetic regulation in vivo.	Potassium	71-73	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	100-105
21699843-3	2011	Protein kinase C (PKC), which is activated by alpha1 adrenergic receptor stimulation, is known to downregulate I(Ks) via phosphorylation of KCNE1 serine 102, but the underlying mechanism has remained enigmatic.	Potassium	113-115	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	140-145
21699843-10	2011	KCNE1-S102A abolished the effect of PMA on I(Ks) currents and endocytosis.	Potassium	45-47	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	0-5
21671256-7	2011	Constitutive and potassium-evoked release of acetylcholine and dopamine was increased and apoptosis induced by hydrogen peroxide (H(2)O(2)) was inhibited in PCP4-induced PC12 cells.	Potassium	17-26	Purkinje cell protein 4	Rattus norvegicus	157-161
21796099-5	2011	Electrophysiological recordings in Xenopus oocytes injected with HCN2 cRNA found that potassium was transported better than ammonium, each of which was transported significantly better than sodium, criteria that are compatible with a role for HCN2 in ammonium transport.	Potassium	86-95	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Rattus norvegicus	65-69
21943416-1	2011	Potassium currents generated by voltage-gated potassium (Kv) channels comprising alpha-subunits from the Kv1, 2, and 3 subfamilies facilitate high-frequency firing of mammalian neurons.	Potassium	0-9	potassium voltage-gated channel subfamily A member 2	Homo sapiens	105-111
21424384-7	2011	The combination of potassium-sparing diuretics plus a potassium supplement, start of the PID within the hospital and hospitalisation in non-internal medicine departments was associated with higher relative risk estimates for hyperkalaemia.	Potassium	19-28	metastasis associated 1 family member 2	Homo sapiens	89-92
21740026-7	2011	Comparing collagen assembly on the two types of mica at different potassium concentrations revealed that potassium binds to the negatively charged mica surface and neutralizes it, thereby reducing the binding affinity of collagen and enhancing surface diffusion.	Potassium	66-75	MHC class I polypeptide-related sequence A	Homo sapiens	147-151
21740026-7	2011	Comparing collagen assembly on the two types of mica at different potassium concentrations revealed that potassium binds to the negatively charged mica surface and neutralizes it, thereby reducing the binding affinity of collagen and enhancing surface diffusion.	Potassium	105-114	MHC class I polypeptide-related sequence A	Homo sapiens	48-52
21740026-7	2011	Comparing collagen assembly on the two types of mica at different potassium concentrations revealed that potassium binds to the negatively charged mica surface and neutralizes it, thereby reducing the binding affinity of collagen and enhancing surface diffusion.	Potassium	105-114	MHC class I polypeptide-related sequence A	Homo sapiens	147-151
21820436-0	2011	Vasopressin, ATP and catecholamines differentially control potassium secretion in inner ear cell line.	Potassium	59-68	arginine vasopressin	Homo sapiens	0-11
21653901-3	2011	Organ culture of endothelium-denuded ovine carotid arteries with 3 ng/ml VEGF-A(165) for 24 h differentially and significantly influenced potassium-induced (55% increase) and stretch-induced (36% decrease) stress-strain relations in adult (n = 18) but not term fetal (n = 21) arteries, suggesting that smooth muscle reactivity to VEGF is acquired during postnatal maturation.	Potassium	138-147	vascular endothelial growth factor A	Homo sapiens	73-77
21841064-6	2011	Compared with those with a GFR &gt;= 50 ml/min per 1.73 m(2), having a GFR &lt; 30 ml/min per 1.73 m(2) was associated with a three-fold higher risk of acidosis and growth failure and a four- to five-fold higher risk of anemia and elevated potassium and phosphate.	Potassium	240-249	Rap guanine nucleotide exchange factor 5	Homo sapiens	71-74
21742892-0	2011	KefF, the regulatory subunit of the potassium efflux system KefC, shows quinone oxidoreductase activity.	Potassium	36-45	thioredoxin reductase 1	Homo sapiens	80-94
21670672-3	2011	RECENT FINDINGS: A variation in sodium and potassium intake or plasma aldosterone changes the number of cleaved alpha and gamma-ENaC subunits and is associated with changes in ENaC currents.	Potassium	43-52	sodium channel epithelial 1 subunit gamma	Homo sapiens	122-132
21683152-0	2011	Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons.	Potassium	77-86	mitogen-activated protein kinase 14	Homo sapiens	43-46
22340870-10	2011	However, in NHBP group, the mean urinary sodium decreased by 1.7 mmol/24 h (t = 0.211, P = 0.417) and urinary potassium increased by 3.7 mmol/24 h (t" = 2.207, P = 0.015), together with the decrease of Na(+)/K(+) by 0.7 (t = 1.818, P = 0.036).	Potassium	110-119	filamin A	Homo sapiens	12-16
21799445-0	2011	Genetic variants in the renin-angiotensin-aldosterone system and blood pressure responses to potassium intake.	Potassium	93-102	renin	Homo sapiens	24-29
21799445-2	2011	We examined the association between genetic variants in the renin-angiotensin-aldosterone system and BP responses to potassium intervention.	Potassium	117-126	renin	Homo sapiens	60-65
21799445-6	2011	For example, the number of G alleles of the N554S missense mutation (rs5527) of NR3C2 was significantly associated with greater SBP responses to potassium intervention; mean [95% confidence interval (CI)] responses (mmHg) were -3.33 (-3.65 to -3.02) for genotype A/A and -5.47 (-6.64 to -4.29) for A/G, respectively (P value = 0.0004).	Potassium	145-154	nuclear receptor subfamily 3 group C member 2	Homo sapiens	80-85
21799445-6	2011	For example, the number of G alleles of the N554S missense mutation (rs5527) of NR3C2 was significantly associated with greater SBP responses to potassium intervention; mean [95% confidence interval (CI)] responses (mmHg) were -3.33 (-3.65 to -3.02) for genotype A/A and -5.47 (-6.64 to -4.29) for A/G, respectively (P value = 0.0004).	Potassium	145-154	selenium binding protein 1	Homo sapiens	128-131
21799445-7	2011	In addition, the number of C alleles of the A1166C variant (rs5186) in AGTR1 was significantly and inversely associated with SBP responses to potassium intervention; mean (95% CI) responses were -3.55 (-3.87 to -3.24) for genotype A/A, -2.45 (-3.27 to -1.62) for A/C, and 3.25 (-5.73 to 12.23) for CC (P value = 0.003).	Potassium	142-151	angiotensin II receptor type 1	Homo sapiens	71-76
21799445-7	2011	In addition, the number of C alleles of the A1166C variant (rs5186) in AGTR1 was significantly and inversely associated with SBP responses to potassium intervention; mean (95% CI) responses were -3.55 (-3.87 to -3.24) for genotype A/A, -2.45 (-3.27 to -1.62) for A/C, and 3.25 (-5.73 to 12.23) for CC (P value = 0.003).	Potassium	142-151	selenium binding protein 1	Homo sapiens	125-128
21799445-8	2011	CONCLUSION: These novel findings indicated that genetic variants in the renin-angiotensin-aldosterone system may play an important role in determining an individual"s BP responses to dietary potassium intake.	Potassium	191-200	renin	Homo sapiens	72-77
21906004-6	2011	Furthermore, translocation of mutant PKC was attenuated when the cells was treated with high potassium solution.	Potassium	93-102	protein kinase C gamma	Homo sapiens	37-40
21843472-2	2011	A number of Kv7.1 pore mutants are sensitive to extracellular potassium.	Potassium	62-71	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	12-17
21843472-0	2011	Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state.	Potassium	14-23	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	33-38
21843472-3	2011	We hypothesized that extracellular potassium also modulates wild-type Kv7.1 channels.	Potassium	35-44	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	70-75
21843472-4	2011	The Kv7.1 currents were measured in Xenopus laevis oocytes at different concentrations of extracellular potassium (1-50 mM).	Potassium	104-113	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	4-9
21843472-5	2011	As extracellular potassium was elevated, Kv7.1 currents were reduced significantly more than expected from theoretical calculations based on the Goldman-Hodgkin-Katz flux equation.	Potassium	17-26	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	41-46
21843472-8	2011	Similarly, the recovery from inactivation was slowed by potassium, suggesting that extracellular potassium stabilizes an inactivated state in Kv7.1 channels.	Potassium	56-65	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	142-147
21843472-8	2011	Similarly, the recovery from inactivation was slowed by potassium, suggesting that extracellular potassium stabilizes an inactivated state in Kv7.1 channels.	Potassium	97-106	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	142-147
21843472-9	2011	The effect of extracellular potassium was absent in noninactivating Kv7.1/KCNE1 and Kv7.1/KCNE3 channels, further supporting a stabilized inactivated state as the underlying mechanism.	Potassium	28-37	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	68-73
21843472-9	2011	The effect of extracellular potassium was absent in noninactivating Kv7.1/KCNE1 and Kv7.1/KCNE3 channels, further supporting a stabilized inactivated state as the underlying mechanism.	Potassium	28-37	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	74-79
21843472-9	2011	The effect of extracellular potassium was absent in noninactivating Kv7.1/KCNE1 and Kv7.1/KCNE3 channels, further supporting a stabilized inactivated state as the underlying mechanism.	Potassium	28-37	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	84-89
21843472-9	2011	The effect of extracellular potassium was absent in noninactivating Kv7.1/KCNE1 and Kv7.1/KCNE3 channels, further supporting a stabilized inactivated state as the underlying mechanism.	Potassium	28-37	potassium channel, voltage gated subfamily E regulatory beta subunit 3 S homeolog	Xenopus laevis	90-95
21843472-11	2011	In a number of other Kv channels, including Kv1.5, Kv4.3, and Kv7.2-5 channels, currents were only minimally reduced by an increase in extracellular potassium as expected.	Potassium	149-158	potassium voltage-gated channel subfamily A member 4 L homeolog	Xenopus laevis	44-49
21843472-11	2011	In a number of other Kv channels, including Kv1.5, Kv4.3, and Kv7.2-5 channels, currents were only minimally reduced by an increase in extracellular potassium as expected.	Potassium	149-158	potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog	Xenopus laevis	51-56
21843472-12	2011	These results show that extracellular potassium modulates Kv7.1 channels and suggests that physiological changes in potassium concentrations may directly control the function of Kv7.1 channels.	Potassium	38-47	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	58-63
21843472-12	2011	These results show that extracellular potassium modulates Kv7.1 channels and suggests that physiological changes in potassium concentrations may directly control the function of Kv7.1 channels.	Potassium	38-47	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	178-183
21843472-12	2011	These results show that extracellular potassium modulates Kv7.1 channels and suggests that physiological changes in potassium concentrations may directly control the function of Kv7.1 channels.	Potassium	116-125	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	58-63
21843472-12	2011	These results show that extracellular potassium modulates Kv7.1 channels and suggests that physiological changes in potassium concentrations may directly control the function of Kv7.1 channels.	Potassium	116-125	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	178-183
21843472-13	2011	This may represent a novel regulatory mechanism of excitability and of potassium transport in tissues expressing Kv7.1 channels.	Potassium	71-80	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	113-118
21849545-6	2011	Moreover, furosemide and bumetanide, two inhibitors of sodium-coupled and/or potassium-coupled chloride movement strongly modified the phase shift, suggesting an involvement of two neuronal cotransporters, NKCC1 (Na-K-Cl) and KCC2 (K-Cl) in the genesis of the optical signal.	Potassium	77-86	solute carrier family 12, member 2	Mus musculus	206-211
21849540-2	2011	Presymptomatic SCA1 mice show a reduction in the firing rate of Purkinje cells (both in vivo and in slices) associated with a reduction in the efficiency of the main glutamatergic synapse onto Purkinje cells and with increased A-type potassium current.	Potassium	234-243	ataxin 1	Mus musculus	15-19
21849545-6	2011	Moreover, furosemide and bumetanide, two inhibitors of sodium-coupled and/or potassium-coupled chloride movement strongly modified the phase shift, suggesting an involvement of two neuronal cotransporters, NKCC1 (Na-K-Cl) and KCC2 (K-Cl) in the genesis of the optical signal.	Potassium	77-86	solute carrier family 12, member 5	Mus musculus	226-230
21732595-1	2011	Potassium Boc-protected aminomethyltrifluoroborate, a primary aminomethyl equivalent, was synthesized successfully through a "one-pot" process.	Potassium	0-9	BOC cell adhesion associated, oncogene regulated	Homo sapiens	10-13
21782438-6	2011	Furthermore, we detected adaptive protein evolution of vkorc1 in M. spretus (Ka/Ks = 1.54-1.93) resulting in radical amino acid substitutions that apparently cause anticoagulant tolerance in M. spretus as a pleiotropic effect.	Potassium	80-82	vitamin K epoxide reductase complex subunit 1	Homo sapiens	55-61
21593184-5	2011	GLP-1-infused rats displayed increased urine flow, fractional excretion of sodium, potassium, and bicarbonate compared with those rats that received vehicle (1% BSA/saline).	Potassium	83-92	glucagon	Rattus norvegicus	0-5
21628512-9	2011	These data suggest that CPE can be absorbed from the intestine into the circulation, followed by the binding of the toxin to internal organs to induce potassium leakage, which can cause death.	Potassium	151-160	cpe	Clostridium perfringens	24-27
21628512-10	2011	Finally, CPE pore complexes similar to those formed in tissue culture cells were detected in the intestine and liver, suggesting that (i) CPE actions are similar in vivo and in vitro and (ii) CPE-induced potassium release into blood may result from CPE pore formation in internal organs such as the liver.	Potassium	204-213	cpe	Clostridium perfringens	9-12
21220753-9	2011	The plasma potassium decreased by a mean of 1.0, 1.7, 2.1 and 2.1 mmol/L at 1, 2, 4 and 8 h, respectively.	Potassium	11-20	solute carrier family 7 member 5	Homo sapiens	71-89
21680658-9	2011	Application of small interfering RNA specific for KCNK5 decreased pH-sensitive potassium currents and also reduced the estrogen-induced proliferation of T47D cells.	Potassium	79-88	potassium two pore domain channel subfamily K member 5	Homo sapiens	50-55
21710140-0	2011	Progressive myoclonic epilepsy-associated gene KCTD7 is a regulator of potassium conductance in neurons.	Potassium	71-80	potassium channel tetramerization domain containing 7	Homo sapiens	47-52
21652713-5	2011	Consistent with these observations, the overexpression of InsP(6)Ks leads to the depletion of Akt phosphorylation and the induction of cell death.	Potassium	65-67	AKT serine/threonine kinase 1	Homo sapiens	94-97
21641965-1	2011	The transcription factor E2F1 is upregulated when cerebellar granular neurons (CGNs) undergo apoptosis under potassium deprivation.	Potassium	109-118	E2F transcription factor 1	Rattus norvegicus	25-29
21641965-5	2011	Furthermore, overexpression of E2F1 significantly promoted apoptotic progression in mouse CGNs following potassium deprivation but attenuated apoptosis in rat CGNs, whereas E2F1 lacking DNA binding ability (E2F1-M132) lost its pro-apoptotic role in mouse CGNs and anti-apoptotic role in rat CGNs.	Potassium	105-114	E2F transcription factor 1	Mus musculus	31-35
21641965-6	2011	Together, our results demonstrated that upregulation of E2F1 by potassium deprivation promotes apoptosis in C57 mouse CGNs but antagonizes apoptosis in SD rat CGNs, suggesting opposing roles for E2F1 in regulating CGN fate.	Potassium	64-73	E2F transcription factor 1	Mus musculus	56-60
21641965-6	2011	Together, our results demonstrated that upregulation of E2F1 by potassium deprivation promotes apoptosis in C57 mouse CGNs but antagonizes apoptosis in SD rat CGNs, suggesting opposing roles for E2F1 in regulating CGN fate.	Potassium	64-73	cingulin	Rattus norvegicus	118-121
21624428-0	2011	Decrease of prestin expression by increased potassium concentration in organotypic cultures of the organ of Corti of newborn rats.	Potassium	44-53	solute carrier family 26 member 5	Rattus norvegicus	12-19
21624428-2	2011	In the present study, we examined the effects of increased extracellular potassium (K(+)) concentration on the expression of prestin mRNA and the transcription factors Gata-3 and Carf in the organotypic culture of the organ of Corti of newborn rats.	Potassium	73-82	solute carrier family 26 member 5	Rattus norvegicus	125-132
21624428-5	2011	Potassium concentration of 35 and 55 mM induced a parallel decrease in prestin and Carf expression, but Gata-3 expression increased.	Potassium	0-9	solute carrier family 26 member 5	Rattus norvegicus	71-78
21624428-5	2011	Potassium concentration of 35 and 55 mM induced a parallel decrease in prestin and Carf expression, but Gata-3 expression increased.	Potassium	0-9	calcium responsive transcription factor	Rattus norvegicus	83-87
21525372-6	2011	However, there was no difference between the two genotypes in potassium-stimulated release of CGRP, the number of action potentials generated by a ramp of depolarizing current, or mechanical hypernociception elicited by intraplantar injection of capsaicin.	Potassium	62-71	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	94-98
21460635-8	2011	In contrast, ULK1, but not ULK2, is critical to induce the autophagic response of cerebellar granule neurons (CGN) to low potassium concentration in serum-free conditions.	Potassium	122-131	unc-51 like autophagy activating kinase 1	Homo sapiens	13-17
21700825-0	2011	A critically swift response: insulin-stimulated potassium and glucose transport in skeletal muscle.	Potassium	48-57	insulin	Homo sapiens	29-36
21734082-1	2011	BACKGROUND AND OBJECTIVES: Insulin has several physiologic actions that include stimulation of cellular glucose and potassium uptake.	Potassium	116-125	insulin	Homo sapiens	27-34
21734082-12	2011	Conclusions Insulin-stimulated intracellular uptake of glucose and potassium are independent of each other.	Potassium	67-76	insulin	Homo sapiens	12-19
21464611-11	2011	As with other agents that induce activation of the NLRP3 inflammasome, the ability of doxorubicin to provide proinflammatory danger signals was inhibited by co-treatment of cells with ROS inhibitors or by incubating cells in high extracellular potassium.	Potassium	244-253	NLR family, pyrin domain containing 3	Mus musculus	51-56
21502286-8	2011	N/OFQ activated a postsynaptic, G-protein coupled, inwardly rectifying potassium (GIRK) current that was sensitive to G-protein inactivation, blocked by the GIRK blocker SCH23390, and occluded by the GABAB agonist and potent GIRK activator, baclofen.	Potassium	71-80	prepronociceptin	Homo sapiens	0-5
21891927-5	2011	RESULTS: When normal cells were exposed to 50 mM potassium buffer, which was used to induce depolarization, the KCNQ3 protein level significantly increased in the membrane fraction but decreased in the cytosolic fraction, whereas the opposite was true in patient cells.	Potassium	49-58	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	112-117
21891927-7	2011	Our results suggest that the altered expression of KCNQ3 in patient cells exposed to high extracellular potassium levels could possibly hinder normal function of the channel protein.	Potassium	104-113	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	51-56
21484879-4	2011	Two kinds of outward currents were found, an A-type (K(A) ) and delayed rectifier (K(DR) ) potassium currents.	Potassium	91-100	kinase insert domain receptor	Rattus norvegicus	83-88
22145415-0	2011	[The effect of potassium different concentrations on mRNA expression of protein StAR and cytochrome p-450(SCC) in human adrenocortical tissue].	Potassium	15-24	steroidogenic acute regulatory protein	Homo sapiens	80-84
22145415-0	2011	[The effect of potassium different concentrations on mRNA expression of protein StAR and cytochrome p-450(SCC) in human adrenocortical tissue].	Potassium	15-24	serpin family B member 3	Homo sapiens	106-109
22145415-1	2011	The effect of different potassium concentrations on changes in steroidogenic acute regulatory protein (StAR) and cytochrome P-450(SCC) in human adrenal cortex tissue was studied.	Potassium	24-33	steroidogenic acute regulatory protein	Homo sapiens	63-101
22145415-1	2011	The effect of different potassium concentrations on changes in steroidogenic acute regulatory protein (StAR) and cytochrome P-450(SCC) in human adrenal cortex tissue was studied.	Potassium	24-33	steroidogenic acute regulatory protein	Homo sapiens	103-107
22145415-1	2011	The effect of different potassium concentrations on changes in steroidogenic acute regulatory protein (StAR) and cytochrome P-450(SCC) in human adrenal cortex tissue was studied.	Potassium	24-33	serpin family B member 3	Homo sapiens	113-134
22145415-3	2011	Thus, potassium ions caused an enhancement of minerocorticoid synthesis in the adrenal cortex, which is associated with mechanisms that regulate the intensity of expression of StAR and cytochrome P-450(SCC) on a transcriptional level.	Potassium	6-15	steroidogenic acute regulatory protein	Homo sapiens	176-180
22145415-3	2011	Thus, potassium ions caused an enhancement of minerocorticoid synthesis in the adrenal cortex, which is associated with mechanisms that regulate the intensity of expression of StAR and cytochrome P-450(SCC) on a transcriptional level.	Potassium	6-15	serpin family B member 3	Homo sapiens	185-206
21498510-4	2011	In our studies we used the voltage-gated hKv1.3 channel, and the insertion of a cysteine at position V388C (Shaker position 438) generated a current through the alpha-pore in high potassium outside and an inward current at hyperpolarizing potentials carried by different cations like Na(+), Li(+), Cs(+), and NH(4)(+).	Potassium	180-189	potassium voltage-gated channel subfamily A member 3	Homo sapiens	41-47
21389090-10	2011	The downregulation of NHE3 and NCC may contribute to the BP-attenuating effect of dietary potassium associated with increased urinary sodium excretion.	Potassium	90-99	solute carrier family 9 member A3	Rattus norvegicus	22-26
21389090-10	2011	The downregulation of NHE3 and NCC may contribute to the BP-attenuating effect of dietary potassium associated with increased urinary sodium excretion.	Potassium	90-99	solute carrier family 12 member 3	Rattus norvegicus	31-34
21619990-1	2011	BACKGROUND: The purpose of this study was to determine whether polarized arrest using adenosine/lidocaine cold crystalloid cardioplegia in combination with the hibernation inductor delta-opioid receptor agonist pentazocine would give satisfactory myocardial protection rather than using depolarized supranormal potassium cardioplegia, supranormal potassium cardioplegia with pentazocine, or adenosine/lidocaine cardioplegia.	Potassium	311-320	opioid receptor delta 1	Sus scrofa	181-202
21454252-0	2011	Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium.	Potassium	79-88	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	27-31
21454252-0	2011	Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium.	Potassium	79-88	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	33-39
21619990-1	2011	BACKGROUND: The purpose of this study was to determine whether polarized arrest using adenosine/lidocaine cold crystalloid cardioplegia in combination with the hibernation inductor delta-opioid receptor agonist pentazocine would give satisfactory myocardial protection rather than using depolarized supranormal potassium cardioplegia, supranormal potassium cardioplegia with pentazocine, or adenosine/lidocaine cardioplegia.	Potassium	347-356	opioid receptor delta 1	Sus scrofa	181-202
21347582-0	2011	Upregulation of calbindin D28k in the late distal tubules in the potassium-loaded adrenalectomized mouse kidney.	Potassium	65-74	calbindin 1	Mus musculus	16-30
21438014-0	2011	HIV-1 gp120 enhances outward potassium current via CXCR4 and cAMP-dependent protein kinase A signaling in cultured rat microglia.	Potassium	29-38	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	6-11
21438014-0	2011	HIV-1 gp120 enhances outward potassium current via CXCR4 and cAMP-dependent protein kinase A signaling in cultured rat microglia.	Potassium	29-38	C-X-C motif chemokine receptor 4	Rattus norvegicus	51-56
21321244-2	2011	The potassium-dependent sodium/calcium exchangers NCKX3 (gene SLC24A3) and NCX1 (gene SLC8A1) play a critical role in the transport of intracellular calcium across the cell membrane in exchange for extracellular sodium ions.	Potassium	4-13	solute carrier family 24 member 3	Homo sapiens	50-55
20827508-0	2011	Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: review of published reports.	Potassium	23-32	insulin	Homo sapiens	110-117
21566059-1	2011	Dietary potassium stimulates the surface expression of ROMK channels in the aldosterone-sensitive distal nephron, but the mechanism by which this occurs is incompletely understood.	Potassium	8-17	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	55-59
21566059-2	2011	Here, a high-potassium diet increased the transcription of microRNA (miR) 802 in the cortical collecting duct in mice.	Potassium	13-22	microRNA 802	Mus musculus	59-77
21566059-3	2011	In addition, high-potassium intake decreased the expression of caveolin-1, whose 3" untranslated region contains the seed sequence of miR-802.	Potassium	18-27	caveolin 1, caveolae protein	Mus musculus	63-73
21566059-3	2011	In addition, high-potassium intake decreased the expression of caveolin-1, whose 3" untranslated region contains the seed sequence of miR-802.	Potassium	18-27	microRNA 802	Mus musculus	134-141
21566059-9	2011	Taken together, miR-802 mediates the stimulatory effect of a high-potassium diet on ROMK channel activity by suppressing caveolin-1 expression, which leads to increased surface expression of ROMK channels in the distal nephron.	Potassium	66-75	microRNA 802	Mus musculus	16-23
21566059-9	2011	Taken together, miR-802 mediates the stimulatory effect of a high-potassium diet on ROMK channel activity by suppressing caveolin-1 expression, which leads to increased surface expression of ROMK channels in the distal nephron.	Potassium	66-75	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	84-88
21566059-9	2011	Taken together, miR-802 mediates the stimulatory effect of a high-potassium diet on ROMK channel activity by suppressing caveolin-1 expression, which leads to increased surface expression of ROMK channels in the distal nephron.	Potassium	66-75	caveolin 1, caveolae protein	Mus musculus	121-131
21566059-9	2011	Taken together, miR-802 mediates the stimulatory effect of a high-potassium diet on ROMK channel activity by suppressing caveolin-1 expression, which leads to increased surface expression of ROMK channels in the distal nephron.	Potassium	66-75	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	191-195
21435166-12	2011	phosphorylated mgp was also found to be present in the first ks patient originally described.	Potassium	61-63	matrix Gla protein	Homo sapiens	15-18
21321244-2	2011	The potassium-dependent sodium/calcium exchangers NCKX3 (gene SLC24A3) and NCX1 (gene SLC8A1) play a critical role in the transport of intracellular calcium across the cell membrane in exchange for extracellular sodium ions.	Potassium	4-13	solute carrier family 24 member 3	Homo sapiens	62-69
21321244-2	2011	The potassium-dependent sodium/calcium exchangers NCKX3 (gene SLC24A3) and NCX1 (gene SLC8A1) play a critical role in the transport of intracellular calcium across the cell membrane in exchange for extracellular sodium ions.	Potassium	4-13	solute carrier family 8 member A1	Homo sapiens	75-79
21321244-2	2011	The potassium-dependent sodium/calcium exchangers NCKX3 (gene SLC24A3) and NCX1 (gene SLC8A1) play a critical role in the transport of intracellular calcium across the cell membrane in exchange for extracellular sodium ions.	Potassium	4-13	solute carrier family 8 member A1	Homo sapiens	86-92
22034819-4	2011	Two-microelectrode voltage clamp experiments had showed that the toxin inhibited Kv2.1 potassium currents expressed in Xenopus Laevis oocytes.	Potassium	87-96	potassium channel, voltage gated Shab related subfamily B, member 1 S homeolog	Xenopus laevis	81-86
21576493-2	2011	The potassium channel, I(Ks), is important for cardiac repolarization and requires PIP(2) to activate.	Potassium	25-27	prolactin induced protein	Homo sapiens	83-86
21470398-7	2011	High extracellular potassium and 10 mM tolbutamide abrogated the inhibition of insulin secretion by GA. Glyceraldehyde, dihydroxyacetone, methylpyruvate, GLP-1, and forskolin, an activator of adenylate cyclase, did not abrogate the inhibition.	Potassium	19-28	insulin	Homo sapiens	79-86
21469677-10	2011	We show T7 RNAP arrest at the c-myb repeat in double-stranded DNA under conditions mimicking the cellular concentration of biomolecules and potassium ions, suggesting that the G4 structure formed in the c-myb repeat may represent a transcription roadblock in vivo.	Potassium	140-149	MYB proto-oncogene, transcription factor	Homo sapiens	30-35
21486764-8	2011	These data suggest an important role of KCC2-dependent potassium/chloride homeostasis under neurototoxic conditions and reveal a novel role of endogenous KCC2 as a neuroprotective molecule.	Potassium	55-64	solute carrier family 12 member 5	Rattus norvegicus	40-44
21484263-4	2011	To assess this, we examined the effects of the female sex hormone beta-estradiol on the human ether-a-go-go-related gene (hERG)-encoded potassium current stably expressed in human embryonic kidney-293 (HEK) cells.	Potassium	136-145	ETS transcription factor ERG	Homo sapiens	122-126
21396765-5	2011	Both FF and FH aptamer dimers exhibited a potassium-dependent inhibitory effect on thrombin-mediated fibrin gel formation, which was on average two-fold higher than those of canonical single stranded Fibri aptamers.	Potassium	42-51	coagulation factor II, thrombin	Homo sapiens	83-91
21183662-14	2011	Electrophysiological recordings from isolated CCK-GFP cells revealed these cells to possess a predominant outwardly rectifying potassium current.	Potassium	127-136	cholecystokinin	Mus musculus	46-49
21270092-4	2011	In addition, we discuss a study reporting on the regulation of the mammalian potassium kidney channel ROMK by intracellular and extracellular magnesium, which may be important in the pathogenesis of persistent hypokalemia in patients with concomitant potassium and magnesium deficiency.	Potassium	77-86	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	102-106
21241800-6	2011	In addition, expression of S277L and wild type KCNQ1 with KCNE1 resulted in a shift of the voltage-dependence of activation by -8.7mV compared to wild type I(Ks), indicating co-assembly of mutant and wild type subunits.	Potassium	158-160	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	47-52
21241800-6	2011	In addition, expression of S277L and wild type KCNQ1 with KCNE1 resulted in a shift of the voltage-dependence of activation by -8.7mV compared to wild type I(Ks), indicating co-assembly of mutant and wild type subunits.	Potassium	158-160	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	58-63
21252158-0	2011	Nuclear factor kappaB downregulates the transient outward potassium current I(to,f) through control of KChIP2 expression.	Potassium	58-67	potassium voltage-gated channel interacting protein 2	Rattus norvegicus	103-109
21214675-5	2011	The other markers for HSC, vimentin and CRBP1, also confirmed the decrease of HSC in the KS type.	Potassium	89-91	vimentin	Rattus norvegicus	27-35
21436285-2	2011	The discovery of WNK kinases (With No lysine = K) now offers new insight to this relationship because WNKs are a crucial molecular pathway connecting hormones such as angiotensin II and aldosterone to renal sodium and potassium transport.	Potassium	218-227	angiotensinogen	Homo sapiens	167-181
21454290-0	2011	Gastrin-releasing peptide modulates fast delayed rectifier potassium current in Per1-expressing SCN neurons.	Potassium	59-68	gastrin releasing peptide	Homo sapiens	0-25
21454290-4	2011	Recordings from Per1 -fluorescent neurons in SCN slices several hours after GRP treatment revealed a significantly greater action potential frequency, a significant increase in voltage-activated outward current at depolarized potentials, and a significant increase in 4-aminopyridine-sensitive fast delayed rectifier (fDR) potassium currents when compared to vehicle-treated slices.	Potassium	323-332	gastrin releasing peptide	Homo sapiens	76-79
21453644-10	2011	CONCLUSIONS: The m.3243A&gt;G mutation not only underlies a dysfunction of the insulin-producing beta cell of the pancreas but also results in a reduction in adenosine triphosphate production of the strial marginal cells of the inner ear, thus diminishing the energy (in the form of potassium ion gradient) needed for the outer hair cells of the organ of Corti to amplify the soundwaves, particularly at high frequencies.	Potassium	283-292	insulin	Homo sapiens	79-86
21402906-8	2011	Our results demonstrate that altered potassium subunit function influences epilepsy susceptibility and implicate Kcnv2 as an epilepsy gene.	Potassium	37-46	potassium voltage-gated channel modifier subfamily V member 2	Homo sapiens	113-118
21338134-0	2011	Structural conversion of intramolecular and intermolecular G-quadruplexes of bcl2mid: the effect of potassium concentration and ion exchange.	Potassium	100-109	BCL2 apoptosis regulator	Homo sapiens	77-81
21338134-7	2011	Furthermore, the spectral changes of bcl2mid when transitioning from sodium form to potassium form take place upon K(+) titration.	Potassium	84-93	BCL2 apoptosis regulator	Homo sapiens	37-41
21233253-5	2011	Simulations predicted that chloroquine effectively blocks potassium flow by binding at the centre of the ion permeation vestibule of Kir2.1.	Potassium	58-67	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	133-139
21205205-8	2011	Using electrophysiology, we found that an analogous mammalian AQP1 N76S mutant excluded protons and potassium ions, but leaked sodium ions, providing an argument for the overwhelming prevalence of Asn over other amino acids.	Potassium	100-109	aquaporin 1 (Colton blood group)	Homo sapiens	62-66
20142818-7	2011	In agreement, higher amounts of dopamine were released from this brain region of NRG1-treated mice following high potassium stimulation.	Potassium	114-123	neuregulin 1	Mus musculus	81-85
21278344-4	2011	All four antibiotics required the NLRP3 inflammasome, the adaptor ASC, and caspase-1 activation to secrete IL-1beta, a process that depended on potassium efflux but was independent of P2X7 receptor.	Potassium	144-153	interleukin 1 beta	Mus musculus	107-115
21191090-5	2011	N/OFQ-induced outward currents persisted in TTX, reversed near the potassium equilibrium potential, and displayed inward rectification, suggesting direct postsynaptic potassium channel activation.	Potassium	67-76	prepronociceptin	Homo sapiens	0-5
21209355-0	2011	Elevated potassium elicits recurrent surges of large GABAA-receptor-mediated post-synaptic currents in hippocampal CA3 pyramidal neurons.	Potassium	9-18	carbonic anhydrase 3	Rattus norvegicus	115-118
21364885-10	2011	A possible role for chloride ions is suggested: the nAChR selectivity was actually reduced by increased chloride gradient (membrane hyperpolarization), while it was increased, moving towards a channel preferentially permeable for potassium, when the chloride gradient was reduced.	Potassium	230-239	cholinergic receptor nicotinic beta 1 subunit	Rattus norvegicus	52-57
21173039-6	2011	The results suggest that activity of these three carriers is sodium/potassium-independent and affected differently by changes in pHo and DeltaPsi: Oatp1a1 was confirmed to be an electroneutral anion exchanger, whereas the function of both OATP1B1 and OATP1B3 was markedly affected by the magnitude of DeltaPsi.	Potassium	68-77	solute carrier organic anion transporter family member 1B1	Homo sapiens	239-246
21173039-6	2011	The results suggest that activity of these three carriers is sodium/potassium-independent and affected differently by changes in pHo and DeltaPsi: Oatp1a1 was confirmed to be an electroneutral anion exchanger, whereas the function of both OATP1B1 and OATP1B3 was markedly affected by the magnitude of DeltaPsi.	Potassium	68-77	solute carrier organic anion transporter family member 1B3	Homo sapiens	251-258
21051417-4	2011	Moreover, insulin is the key component of glucose-insulin-potassium cocktail and exerts significant cardiovascular protective effect via a phosphatidylinositol 3"-kinase-protein kinase B-endothelial nitric oxide synthase (PI3K-Akt-eNOS)-dependent signalling mechanism in addition to its metabolic modulation, which renders it a potent organ protector in multiple clinical applications.	Potassium	58-67	insulin	Homo sapiens	10-17
21294877-5	2011	In addition, we demonstrate that induction of SP and ECR1-TAC1prom activity in these larger diameter neurones can be induced by potassium depolarisation suggesting that, in addition to capsaicin induction, transgene activity may be modulated by voltage gated calcium channels.	Potassium	128-137	tachykinin precursor 1	Homo sapiens	58-62
21118817-4	2011	In cerebellar granule neurons (CGNs) primed to undergo apoptosis by low potassium treatment, expression of HDAC7 protein is reduced.	Potassium	72-81	histone deacetylase 7	Mus musculus	107-112
21118817-6	2011	Forced expression of HDAC7 in cultured CGNs blocks low potassium-induced death, and shRNA-mediated suppression of its expression induces death in otherwise healthy neurons.	Potassium	55-64	histone deacetylase 7	Mus musculus	21-26
20942808-2	2011	In Saccharomyces cerevisiae, the Nha1 Na(+) /H(+) -antiporter and Ena1 Na(+) -ATPase, mediate the efflux of toxic sodium and surplus potassium.	Potassium	133-142	Nha1p	Saccharomyces cerevisiae S288C	33-37
20672326-2	2011	In this study, we observed that BNP increased the tetraethylammonium chloride (TEA)-sensitive delayed rectifier outward potassium current (I(K)) in mouse Schwann cells (SCs) using whole-cell recording techniques.	Potassium	120-129	natriuretic peptide type B	Mus musculus	32-35
21143561-2	2011	Yeast strains lacking the PPZ1 and PPZ2 phosphatase genes, which aberrantly accumulate potassium, are sensitive to agents causing replicative stress or DNA damage and present a cell cycle delay in the G(1) /S phase.	Potassium	87-96	salt homeostasis regulator	Saccharomyces cerevisiae S288C	26-30
21143561-2	2011	Yeast strains lacking the PPZ1 and PPZ2 phosphatase genes, which aberrantly accumulate potassium, are sensitive to agents causing replicative stress or DNA damage and present a cell cycle delay in the G(1) /S phase.	Potassium	87-96	salt homeostasis regulator	Saccharomyces cerevisiae S288C	35-39
21143561-6	2011	As we reported previously, internal potassium accumulation activates the Slt2 MAP kinase pathway.	Potassium	36-45	mitogen-activated serine/threonine-protein kinase SLT2	Saccharomyces cerevisiae S288C	73-77
21278776-0	2011	Angiotensin II: a candidate for an aldosterone-independent mediator of potassium preservation during volume depletion.	Potassium	71-80	angiotensinogen	Homo sapiens	0-14
20927043-1	2011	ROMK1 channels are located in the apical membrane of the connecting tubule and cortical collecting duct and mediate the potassium secretion during normal dietary intake.	Potassium	120-129	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-5
20927043-10	2011	Hence, angiotensin II may have an important role in suppressing potassium secretion during volume depletion.	Potassium	64-73	angiotensinogen	Homo sapiens	7-21
21278776-4	2011	now propose that angiotensin II inhibits the renal outer medullary potassium channel (ROMK1) through stimulation of the protein tyrosine kinase c-Src, perhaps acting as a signal to differentiate volume depletion from a high-potassium diet.	Potassium	67-76	angiotensinogen	Homo sapiens	17-31
21120454-5	2011	hERG channels were expressed in Xenopus laevis oocytes and human embryonic kidney (HEK 293) cells, and potassium currents were recorded using patch clamp and two-electrode voltage clamp electrophysiology.	Potassium	103-112	ETS transcription factor ERG	Homo sapiens	0-4
21461038-4	2011	Furthermore, systematic glucose-insulin-potassium infusion (GIK) has been studied to improve outcome after AMI.	Potassium	40-49	insulin	Homo sapiens	32-39
21278776-4	2011	now propose that angiotensin II inhibits the renal outer medullary potassium channel (ROMK1) through stimulation of the protein tyrosine kinase c-Src, perhaps acting as a signal to differentiate volume depletion from a high-potassium diet.	Potassium	67-76	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	86-91
21278776-4	2011	now propose that angiotensin II inhibits the renal outer medullary potassium channel (ROMK1) through stimulation of the protein tyrosine kinase c-Src, perhaps acting as a signal to differentiate volume depletion from a high-potassium diet.	Potassium	67-76	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	144-149
21405864-1	2011	We have studied the dynamics of chloride and potassium ions in the interior of the Outer membrane porin F (OmpF) under the influence of an external electric field.	Potassium	45-54	voltage dependent anion channel 1	Homo sapiens	98-103
20880994-4	2011	Here, we show that single-stranded DNA modeled from the template strand of the BCL2 MBR, forms secondary structures that migrate faster on native PAGE in the presence of potassium, due to the formation of intramolecular G-quadruplexes.	Potassium	170-179	BCL2 apoptosis regulator	Homo sapiens	79-83
20696528-0	2011	GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus.	Potassium	80-89	G protein-coupled estrogen receptor 1	Rattus norvegicus	0-5
20923597-9	2011	Intakes of PUFA (6-12 years), vitamins B1 (2-5 and 13-18 years), B2 (13-18 years), A (2-5 and 13-18 years) and E (13-18 years) were higher in those groups consuming &gt;= 3 0 servings of WG/d; intakes of added sugars (2-5 years), vitamin C (2-5 and 6-12 years), potassium and sodium (6-12 years) were lower.	Potassium	262-271	pumilio RNA binding family member 3	Homo sapiens	11-15
21084310-2	2011	The assembly of KCNQ1 with KCNE1 generates the delayed rectifier current I(Ks) in the heart.	Potassium	75-77	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	16-21
21084310-2	2011	The assembly of KCNQ1 with KCNE1 generates the delayed rectifier current I(Ks) in the heart.	Potassium	75-77	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	27-32
21176777-5	2011	Interestingly, we found that SVCT2 could be positively modulated by potassium-induced depolarization of myotubes.	Potassium	68-77	solute carrier family 23 member 2	Gallus gallus	29-34
21106862-10	2011	Pioglitazone also suppressed potassium-mediated CYP11B2 induction, but not N6-2"-O-dibutyladenosine-3",5"-cyclic monophosphate stimulation.	Potassium	29-38	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	48-55
21368885-0	2011	Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration.	Potassium	97-106	caspase 8	Homo sapiens	29-36
21051542-1	2011	The NALP3 inflammasome is activated by low intracellular potassium concentrations [K(+)](i), leading to the secretion of the proinflammatory cytokine IL-1beta.	Potassium	57-66	NLR family pyrin domain containing 3	Homo sapiens	4-9
20955764-5	2011	Each of the four VGCCs, P/Q-, N-, and L- and T-type are abundantly found in TG and TNC relative to the dura mater and each mediates a significant fraction of high potassium concentration induced CGRP release.	Potassium	163-172	calcitonin-related polypeptide alpha	Rattus norvegicus	195-199
20955764-8	2011	In the TG omega-conotoxin GVIA inhibited the potassium induced CGRP release significantly.	Potassium	45-54	calcitonin-related polypeptide alpha	Rattus norvegicus	63-67
20955764-11	2011	These results suggest that depolarization by high potassium releases CGRP, and the release is regulated by Ca2+ ions and voltage-gated calcium channels.	Potassium	50-59	calcitonin-related polypeptide alpha	Rattus norvegicus	69-73
21187374-7	2011	Posttranslational modification of the phloem-expressed Arabidopsis K(+) channel AKT2 taps this "potassium battery," which then efficiently assists the plasma membrane H(+)-ATPase in energizing the transmembrane phloem (re)loading processes.	Potassium	96-105	potassium transport 2/3	Arabidopsis thaliana	80-84
21187374-7	2011	Posttranslational modification of the phloem-expressed Arabidopsis K(+) channel AKT2 taps this "potassium battery," which then efficiently assists the plasma membrane H(+)-ATPase in energizing the transmembrane phloem (re)loading processes.	Potassium	96-105	plasma membrane H+-ATPase	Arabidopsis thaliana	151-178
21059661-1	2011	In vivo, KCNQ1 alpha-subunits associate with the beta-subunit KCNE1 to generate the slowly activating cardiac potassium current (I(Ks)).	Potassium	110-119	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	9-14
21051542-1	2011	The NALP3 inflammasome is activated by low intracellular potassium concentrations [K(+)](i), leading to the secretion of the proinflammatory cytokine IL-1beta.	Potassium	57-66	interleukin 1 beta	Homo sapiens	150-158
21059661-1	2011	In vivo, KCNQ1 alpha-subunits associate with the beta-subunit KCNE1 to generate the slowly activating cardiac potassium current (I(Ks)).	Potassium	110-119	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	62-67
21209188-5	2011	One such gene--KCNAB2--encodes the potassium channel auxiliary subunit Kvbeta2, which has been previously shown to modulate voltage-gated potassium currents in heterologous expression systems.	Potassium	35-44	potassium voltage-gated channel, shaker-related subfamily, beta member 2	Mus musculus	15-21
21059661-1	2011	In vivo, KCNQ1 alpha-subunits associate with the beta-subunit KCNE1 to generate the slowly activating cardiac potassium current (I(Ks)).	Potassium	131-133	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	9-14
21059661-1	2011	In vivo, KCNQ1 alpha-subunits associate with the beta-subunit KCNE1 to generate the slowly activating cardiac potassium current (I(Ks)).	Potassium	131-133	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	62-67
21219845-2	2011	Aldosterone activates expression of KS-WNK1 and inhibits WNK4 via SGK1 - both leading to stimulation of ENaC and activation of ROMK, and increased potassium excretion.	Potassium	147-156	WNK lysine deficient protein kinase 1	Homo sapiens	39-43
21219845-2	2011	Aldosterone activates expression of KS-WNK1 and inhibits WNK4 via SGK1 - both leading to stimulation of ENaC and activation of ROMK, and increased potassium excretion.	Potassium	147-156	WNK lysine deficient protein kinase 4	Homo sapiens	57-61
21219845-2	2011	Aldosterone activates expression of KS-WNK1 and inhibits WNK4 via SGK1 - both leading to stimulation of ENaC and activation of ROMK, and increased potassium excretion.	Potassium	147-156	serum/glucocorticoid regulated kinase 1	Homo sapiens	66-70
21209188-5	2011	One such gene--KCNAB2--encodes the potassium channel auxiliary subunit Kvbeta2, which has been previously shown to modulate voltage-gated potassium currents in heterologous expression systems.	Potassium	35-44	potassium voltage-gated channel, shaker-related subfamily, beta member 2	Mus musculus	71-78
21865851-7	2011	Similarly, beta(3)-AR activation induced time-dependent shortening of action potential duration (APD), together with decrease of L-type calcium current (I(Ca,L)) and increase of inward rectifier potassium current (I(K1)) and transient outward potassium current (I(to)) in rapid pacing atrial myocytes.	Potassium	195-204	adrenoceptor beta 3	Homo sapiens	11-21
21850764-5	2011	In addition, the potassium efflux can lead to the accumulation of potassium ions in the intercellular space and the subsequent activation of smooth muscle Kir2.1 and/or Na(+)/K(+)-ATPase.	Potassium	17-26	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	155-161
21850764-5	2011	In addition, the potassium efflux can lead to the accumulation of potassium ions in the intercellular space and the subsequent activation of smooth muscle Kir2.1 and/or Na(+)/K(+)-ATPase.	Potassium	66-75	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	155-161
21849775-8	2011	Positive linear correlations between serum albumin and potassium concentration were only found in the hypoK and normoK groups (p &lt; 0.001).	Potassium	55-64	albumin	Homo sapiens	43-50
22179005-0	2011	Curcumin blocks Kv11.1 (erg) potassium current and slows proliferation in the infant acute monocytic leukemia cell line THP-1.	Potassium	29-38	potassium voltage-gated channel modifier subfamily V member 2	Homo sapiens	16-22
22163310-7	2011	Electrophysiological characterization indicated that passive conductance with large delayed rectifying potassium current might be a uniform feature of non-induced radial glia-like cells.	Potassium	103-112	ral guanine nucleotide dissociation stimulator,-like 1	Mus musculus	163-179
22178878-1	2011	BACKGROUND/AIMS: ROMK channels mediate potassium secretion and regulate NaCl reabsorption in the kidney.	Potassium	39-48	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	17-21
21774764-2	2011	Based on kinetic properties and drug sensitivity it is composed of a slow (I(Ks)) and a rapid (I(Kr)) component, the latter is mediated by hERG channels.	Potassium	77-79	ETS transcription factor ERG	Homo sapiens	139-143
20932251-2	2011	Such a desensitization process is triggered by the activation of the transient receptor potential vanilloid subtype 1 receptor channels (TRPV1) that open their cationic pores, permeable to sodium, potassium and calcium (Ca(2+)) ions.	Potassium	197-206	transient receptor potential cation channel subfamily V member 1	Homo sapiens	137-142
22194651-10	2011	Moreover, AVP secretion was not detected by stimulation with a high potassium (50 mM) solution.	Potassium	68-77	arginine vasopressin	Rattus norvegicus	10-13
21335993-4	2011	Milk is an important source of minerals supporting growth (type II nutrients), such as potassium, magnesium, phosphorus and zinc, and the high lactose content also seems to support growth due to a prebiotic effect and improved absorption of minerals.	Potassium	87-96	Weaning weight-maternal milk	Bos taurus	0-4
22323035-3	2011	On admission, she presented with metabolic alkalosis with hypokalemia, a high urinary excretion of potassium, low plasma rennin activity and hypoaldosteronism.	Potassium	99-108	Src homology 2 domain containing E	Homo sapiens	14-17
22001995-0	2011	Neuropeptide FF receptor modulates potassium currents in a dorsal root ganglion cell line.	Potassium	35-44	neuropeptide FF-amide peptide precursor	Rattus norvegicus	0-15
22001995-3	2011	The whole-cell planar patch-clamp technique showed that dNPA, a selective NPFF(2) agonist, increased the voltage-dependent potassium outward currents (about 30 pA/pF) by 21%; this reversible effect on sustained delayed potassium currents is blocked by tetraethylammonium.	Potassium	123-132	neuropeptide FF-amide peptide precursor	Rattus norvegicus	74-78
22145034-0	2011	SLO-2 is cytoprotective and contributes to mitochondrial potassium transport.	Potassium	57-66	potassium channel, subfamily T, member 1	Mus musculus	0-5
22073228-11	2011	CONCLUSIONS: The results of our study indicate that N-terminal arginines in positions 32, 33, 36 of KCNE1 are important for reconstitution of I(Ks).	Potassium	144-146	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	100-105
22022562-7	2011	The C-terminal half of OFD1 is under relaxed selection with an elevated Ka/Ks ratio and clustered positively selected sites, whereas the N-terminal half is under stronger constraints.	Potassium	75-77	OFD1 centriole and centriolar satellite protein	Homo sapiens	23-27
22073228-8	2011	I(Ks) resulting from co-expression of Kv7.1 with non-atrial fibrillation "38S" was greater than with any other construct.	Potassium	2-4	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	38-43
21915266-1	2011	Of the five human KCNQ (Kv7) channels, KCNQ1 with auxiliary subunit KCNE1 mediates the native cardiac I(Ks) current with mutations causing short and long QT cardiac arrhythmias.	Potassium	104-106	KCNQ potassium channel	Drosophila melanogaster	18-22
21915266-1	2011	Of the five human KCNQ (Kv7) channels, KCNQ1 with auxiliary subunit KCNE1 mediates the native cardiac I(Ks) current with mutations causing short and long QT cardiac arrhythmias.	Potassium	104-106	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	39-44
21915266-1	2011	Of the five human KCNQ (Kv7) channels, KCNQ1 with auxiliary subunit KCNE1 mediates the native cardiac I(Ks) current with mutations causing short and long QT cardiac arrhythmias.	Potassium	104-106	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	68-73
21625424-5	2011	All three drugs induced potassium efflux from the cells as a known mechanism for NLRP3 activation but the P2X7 receptor was not required for this process.	Potassium	24-33	NLR family, pyrin domain containing 3	Mus musculus	81-86
21625424-7	2011	Together, the polyene macrolides amphotericin B, nystatin, and natamycin trigger IL-1beta secretion by causing potassium efflux from which activates the NLRP3-ASC-caspase-1.	Potassium	111-120	interleukin 1 beta	Mus musculus	81-89
21625424-7	2011	Together, the polyene macrolides amphotericin B, nystatin, and natamycin trigger IL-1beta secretion by causing potassium efflux from which activates the NLRP3-ASC-caspase-1.	Potassium	111-120	NLR family, pyrin domain containing 3	Mus musculus	153-158
21625424-7	2011	Together, the polyene macrolides amphotericin B, nystatin, and natamycin trigger IL-1beta secretion by causing potassium efflux from which activates the NLRP3-ASC-caspase-1.	Potassium	111-120	steroid sulfatase	Mus musculus	159-162
21625424-7	2011	Together, the polyene macrolides amphotericin B, nystatin, and natamycin trigger IL-1beta secretion by causing potassium efflux from which activates the NLRP3-ASC-caspase-1.	Potassium	111-120	caspase 1	Mus musculus	163-172
20870010-3	2010	Growing sensory neurons in 30 or 100 ng/mL of NGF for 7 days increases CGRP content and this increase augments the amount of CGRP that is released by high extracellular potassium.	Potassium	169-178	calcitonin related polypeptide alpha	Homo sapiens	125-129
20808327-10	2010	However, potassium intake (mg/1000 kcal) was shown to be inversely associated with hypertension development (upper tertile: &gt;1863.0 for women and &gt;1657.2 for men) vs first tertile (IRR=0.65 (0.44-0.96), P for trend=0.025).	Potassium	9-18	insulin receptor related receptor	Homo sapiens	187-190
21158686-1	2010	The voltage-gated potassium channel, human Ether-a-go-go related gene (hERG), represents the molecular component of IKr, one of the potassium currents involved in cardiac action potential repolarization.	Potassium	18-27	ETS transcription factor ERG	Homo sapiens	71-75
20486869-2	2010	The final step in RAAS stimulation is aldosterone secretion by angiotensin II, which leads to increased renal tubular sodium absorption and potassium secretion.	Potassium	140-149	angiotensinogen	Homo sapiens	63-77
20883817-7	2010	The phosphorylation of mammalian target of rapamycin (mTOR) was also depressed in cells overexpressing InsP(6)Ks, suggesting that the mTOR pathway regulates autophagosomes generated by InsP(6)Ks.	Potassium	110-112	mechanistic target of rapamycin kinase	Homo sapiens	23-52
20861505-8	2010	Angiotensin II receptor, type 1 (AGTR1), single-nucleotide polymorphism rs16860760 in the 3q24-q26.1 region was significantly associated with absolute and percent systolic BP responses to potassium (P=0.0008 and P=0.0006, respectively).	Potassium	188-197	angiotensin II receptor type 1	Homo sapiens	0-31
20861505-8	2010	Angiotensin II receptor, type 1 (AGTR1), single-nucleotide polymorphism rs16860760 in the 3q24-q26.1 region was significantly associated with absolute and percent systolic BP responses to potassium (P=0.0008 and P=0.0006, respectively).	Potassium	188-197	angiotensin II receptor type 1	Homo sapiens	33-38
20861505-12	2010	Furthermore, the AGTR1 gene was a significant predictor of BP responses to potassium intake.	Potassium	75-84	angiotensin II receptor type 1	Homo sapiens	17-22
20883817-7	2010	The phosphorylation of mammalian target of rapamycin (mTOR) was also depressed in cells overexpressing InsP(6)Ks, suggesting that the mTOR pathway regulates autophagosomes generated by InsP(6)Ks.	Potassium	110-112	mechanistic target of rapamycin kinase	Homo sapiens	54-58
20883817-7	2010	The phosphorylation of mammalian target of rapamycin (mTOR) was also depressed in cells overexpressing InsP(6)Ks, suggesting that the mTOR pathway regulates autophagosomes generated by InsP(6)Ks.	Potassium	110-112	mechanistic target of rapamycin kinase	Homo sapiens	134-138
20883817-7	2010	The phosphorylation of mammalian target of rapamycin (mTOR) was also depressed in cells overexpressing InsP(6)Ks, suggesting that the mTOR pathway regulates autophagosomes generated by InsP(6)Ks.	Potassium	192-194	mechanistic target of rapamycin kinase	Homo sapiens	23-52
20883817-7	2010	The phosphorylation of mammalian target of rapamycin (mTOR) was also depressed in cells overexpressing InsP(6)Ks, suggesting that the mTOR pathway regulates autophagosomes generated by InsP(6)Ks.	Potassium	192-194	mechanistic target of rapamycin kinase	Homo sapiens	54-58
20883817-7	2010	The phosphorylation of mammalian target of rapamycin (mTOR) was also depressed in cells overexpressing InsP(6)Ks, suggesting that the mTOR pathway regulates autophagosomes generated by InsP(6)Ks.	Potassium	192-194	mechanistic target of rapamycin kinase	Homo sapiens	134-138
20853142-0	2010	Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: a unique clinical/physiologic exercise in internal potassium balance.	Potassium	23-32	insulin	Homo sapiens	110-117
20853142-0	2010	Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: a unique clinical/physiologic exercise in internal potassium balance.	Potassium	170-179	insulin	Homo sapiens	110-117
20853142-4	2010	Calculations of transcellular potassium shifts based on the combined effects of insulin-the increase in the electrical potential differences (hyperpolarization) of the cell membranes and the correction of the hyperglycemic intracellular dehydration through decrease in serum glucose concentration-produced quantitative predictions of the decrease in serum K(+) similar to the reported changes in serum K(+) during treatment of DH with insulin.	Potassium	30-39	insulin	Homo sapiens	80-87
20853142-4	2010	Calculations of transcellular potassium shifts based on the combined effects of insulin-the increase in the electrical potential differences (hyperpolarization) of the cell membranes and the correction of the hyperglycemic intracellular dehydration through decrease in serum glucose concentration-produced quantitative predictions of the decrease in serum K(+) similar to the reported changes in serum K(+) during treatment of DH with insulin.	Potassium	30-39	insulin	Homo sapiens	435-442
20853142-5	2010	The lessons from analyzing serum K(+) changes during treatment of DH with insulin are applicable to other conditions where internal potassium balance is called upon to protect serum K(+), such as the postprandial state.	Potassium	132-141	insulin	Homo sapiens	74-81
21224508-3	2010	Here the action potential (AP) voltage clamp technique was used to elucidate the effect of S140G KCNQ1 on the profile of recombinant I(Ks) during atrial and ventricular APs applied to KCNQ1+KCNE1 expressing CHO cells, at 37 C. Under conventional voltage clamp the S140G KCNQ1 mutation shifted voltage-dependent activation by  -62 mV, with a marked instantaneous current component evident on membrane depolarisation.	Potassium	135-137	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	97-102
20936693-4	2010	PNMA1 expression increases in cerebellar granule neurons (CGNs) induced to die by low potassium (LK) and in cortical neurons following homocysteic acid (HCA) treament.	Potassium	86-95	paraneoplastic antigen MA1	Mus musculus	0-5
20936693-7	2010	Ectopic expression of PNMA1 promotes apoptosis even in medium containing high potassium, a condition that normally ensures survival of CGNs.	Potassium	78-87	paraneoplastic antigen MA1	Mus musculus	22-27
21224508-3	2010	Here the action potential (AP) voltage clamp technique was used to elucidate the effect of S140G KCNQ1 on the profile of recombinant I(Ks) during atrial and ventricular APs applied to KCNQ1+KCNE1 expressing CHO cells, at 37 C. Under conventional voltage clamp the S140G KCNQ1 mutation shifted voltage-dependent activation by  -62 mV, with a marked instantaneous current component evident on membrane depolarisation.	Potassium	135-137	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	184-189
21224508-3	2010	Here the action potential (AP) voltage clamp technique was used to elucidate the effect of S140G KCNQ1 on the profile of recombinant I(Ks) during atrial and ventricular APs applied to KCNQ1+KCNE1 expressing CHO cells, at 37 C. Under conventional voltage clamp the S140G KCNQ1 mutation shifted voltage-dependent activation by  -62 mV, with a marked instantaneous current component evident on membrane depolarisation.	Potassium	135-137	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	190-195
21224508-3	2010	Here the action potential (AP) voltage clamp technique was used to elucidate the effect of S140G KCNQ1 on the profile of recombinant I(Ks) during atrial and ventricular APs applied to KCNQ1+KCNE1 expressing CHO cells, at 37 C. Under conventional voltage clamp the S140G KCNQ1 mutation shifted voltage-dependent activation by  -62 mV, with a marked instantaneous current component evident on membrane depolarisation.	Potassium	135-137	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	184-189
21106816-0	2010	Implication of Kir4.1 channel in excess potassium clearance: an in vivo study on anesthetized glial-conditional Kir4.1 knock-out mice.	Potassium	40-49	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	15-21
20970925-7	2010	Similarly, concentration-dependent inhibition of CGRP release was observed when deltorphin and morphine were administered in sequence prior to potassium stimulation.	Potassium	143-152	calcitonin-related polypeptide alpha	Rattus norvegicus	49-53
21437011-8	2010	The secretion of IL-1beta was also increased by nigericin in WT mice and the secretory effect of a combination of ivermectin with ATP in KO mice was suppressed in a medium containing a high concentration of potassium.	Potassium	207-216	interleukin 1 beta	Mus musculus	17-25
20638488-1	2010	By using a 2-DE based workflow, the proteome of wild and potassium transport mutant trk1,2 under optimal growth potassium concentration (50mM) has been analyzed.	Potassium	57-66	Trk1p	Saccharomyces cerevisiae S288C	84-88
20585026-3	2010	We hypothesize that the antimalarial quinoline chloroquine exerts potent antiarrhythmic effects by interacting with the cytoplasmic domains of Kir2.1 (I(K1)), Kir3.1 (I(KACh)), or Kir6.2 (I(KATP)) and reducing inward rectifier potassium currents.	Potassium	227-236	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	143-149
20833965-2	2010	Interestingly, the expressed pore mutants of HERG and KvLQT1 downregulated the remaining reciprocal repolarizing currents, I(Ks) and I(Kr), without affecting the steady-state levels of the native polypeptides.	Potassium	125-127	potassium voltage-gated channel subfamily KQT member 1	Oryctolagus cuniculus	54-60
20585026-6	2010	Comparative molecular modeling and ligand docking of chloroquine in the intracellular domains of Kir2.1, Kir3.1, and Kir6.2 suggested that chloroquine blocks or reduces potassium flow by interacting with negatively charged amino acids facing the ion permeation vestibule of the channel in question.	Potassium	169-178	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	97-103
20585026-6	2010	Comparative molecular modeling and ligand docking of chloroquine in the intracellular domains of Kir2.1, Kir3.1, and Kir6.2 suggested that chloroquine blocks or reduces potassium flow by interacting with negatively charged amino acids facing the ion permeation vestibule of the channel in question.	Potassium	169-178	potassium inwardly rectifying channel subfamily J member 3	Homo sapiens	105-111
20585026-6	2010	Comparative molecular modeling and ligand docking of chloroquine in the intracellular domains of Kir2.1, Kir3.1, and Kir6.2 suggested that chloroquine blocks or reduces potassium flow by interacting with negatively charged amino acids facing the ion permeation vestibule of the channel in question.	Potassium	169-178	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	117-123
20659170-4	2010	We found for the first time that in the absence of Arl1p, Kha1p increases potassium, sodium and lithium tolerance, and can thus be categorized as an antiporter with broad substrate specificity.	Potassium	74-83	Kha1p	Saccharomyces cerevisiae S288C	58-63
20629190-7	2010	ATP-induced release of CatS required potassium efflux and both extracellular calcium influx and mobilization of intracellular calcium.	Potassium	37-46	cathepsin S	Felis catus	23-27
20573049-0	2010	AtNHX3 is a vacuolar K+/H+ antiporter required for low-potassium tolerance in Arabidopsis thaliana.	Potassium	55-64	Na+/H+ (sodium hydrogen) exchanger 3	Arabidopsis thaliana	0-6
20801131-4	2010	We show that, although the two waveforms elicited from resting conditions as a single AP are very similar and belong to membranes sharing similar passive electrical properties, the modified membrane generating AP2 is a weaker current source than the one generating AP1, has different sensitivity to up/down-regulation of ion channels and to extracellular potassium, and a different electrical restitution profile.	Potassium	355-364	transcription factor AP-2 alpha	Homo sapiens	210-213
21104767-2	2010	NCKX3 (gene SLC24A3), a potassium-dependent sodium-/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions.	Potassium	24-33	solute carrier family 24 member 3	Rattus norvegicus	0-5
21104767-2	2010	NCKX3 (gene SLC24A3), a potassium-dependent sodium-/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions.	Potassium	24-33	solute carrier family 24 member 3	Rattus norvegicus	12-19
20615442-7	2010	Injection of NTN one day prior to 6-OHDA also led to significant protection against loss of both potassium- and amphetamine-evoked overflow of dopamine.	Potassium	97-106	neurturin	Rattus norvegicus	13-16
20573049-10	2010	The overall results indicate that AtNHX3 encodes a K+/H+ antiporter required for low-potassium tolerance during germination and early seedling development, and may function in K+ utilization and ion homeostasis in Arabidopsis.	Potassium	85-94	Na+/H+ (sodium hydrogen) exchanger 3	Arabidopsis thaliana	34-40
21273684-0	2010	Gain of function of Kir4.1 channel increases cell resistance to changes of potassium fluxes and cell volume evoked by ammonia and hypoosmotic stress.	Potassium	75-84	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	20-26
20842761-3	2010	The objective of this study was to determine the effects of selective COX-2 inhibitors and non-selective nonsteroidal anti-inflammatory drugs (NSAIDs) on serum potassium concentration and the electrocardiogram.	Potassium	160-169	prostaglandin-endoperoxide synthase 2	Homo sapiens	70-75
20842761-7	2010	RESULTS: Compared to patients prescribed non-selective NSAIDs, those prescribed a selective COX-2 inhibitor had a higher risk of serum potassium increase greater than 5 mEq/L (OR, 2.56; 95%CI, 1.03-6.36).	Potassium	135-144	prostaglandin-endoperoxide synthase 2	Homo sapiens	92-97
21273684-1	2010	The Kir4.1 channel is an inward rectifying potassium channel involved in the control of potassium and water movement in mammalian cells.	Potassium	43-52	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	4-10
21273684-8	2010	The results demonstrate that the presence of Kir4.1 in cells increases their resistance to alterations of potassium fluxes and/or cell volume imposed by ammonia and hypotonicity.	Potassium	106-115	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	45-51
21433378-0	2010	Discovery of a small molecule inhibitor of ROMK and Kir7.1 The specific aim of this project is to identify small molecule inhibitors of Renal Outer Medullary Potassium Channel (ROMK, Kir1.1, KCNJ1), a potassium channel located in the renal tubule, where it critically regulates sodium and potassium balance.	Potassium	201-210	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	43-47
21433391-0	2010	Discovery of a small molecule inhibitor of ROMK with unprecedented selectivity The specific aim of this project is to identify small molecule inhibitors of Renal Outer Medullary Potassium Channel (ROMK, Kir1.1, KCNJ1), a potassium channel located in the renal tubule, where it critically regulates sodium and potassium balance.	Potassium	221-230	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	43-47
20921400-6	2010	Moreover, the expression of the ROMK and BKCa potassium channels was modified in KS-WNK1(-/-) mice, indicating that KS-WNK1 is also a regulator of potassium transport in the distal nephron.	Potassium	46-55	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	Mus musculus	41-45
20921400-6	2010	Moreover, the expression of the ROMK and BKCa potassium channels was modified in KS-WNK1(-/-) mice, indicating that KS-WNK1 is also a regulator of potassium transport in the distal nephron.	Potassium	46-55	WNK lysine deficient protein kinase 1	Mus musculus	84-88
20921400-6	2010	Moreover, the expression of the ROMK and BKCa potassium channels was modified in KS-WNK1(-/-) mice, indicating that KS-WNK1 is also a regulator of potassium transport in the distal nephron.	Potassium	46-55	WNK lysine deficient protein kinase 1	Mus musculus	119-123
20607461-1	2010	The human ether a go-go related gene (hERG) voltage-gated potassium controls the rapid delayed rectifier potassium current (I(ks)) in heart.	Potassium	58-67	ETS transcription factor ERG	Homo sapiens	38-42
20820615-0	2010	Sodium and potassium compounds of [(eta(6)-benzenecarboxylate)Cr(CO)(3)] and [(eta(6)-1,4-benzenedicarboxylate)Cr(CO)(3)].	Potassium	11-20	endothelin receptor type A	Homo sapiens	36-39
20820615-0	2010	Sodium and potassium compounds of [(eta(6)-benzenecarboxylate)Cr(CO)(3)] and [(eta(6)-1,4-benzenedicarboxylate)Cr(CO)(3)].	Potassium	11-20	endothelin receptor type A	Homo sapiens	79-82
20660394-9	2010	Further characterization of the role of the R190Q-KCNQ1 mutation in the pathogenesis of long-QT syndrome type 1 revealed a dominant negative trafficking defect associated with a 70 to 80% reduction in I(Ks) current and altered channel activation and deactivation properties.	Potassium	203-205	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	50-55
20607461-1	2010	The human ether a go-go related gene (hERG) voltage-gated potassium controls the rapid delayed rectifier potassium current (I(ks)) in heart.	Potassium	126-128	ETS transcription factor ERG	Homo sapiens	38-42
20607461-1	2010	The human ether a go-go related gene (hERG) voltage-gated potassium controls the rapid delayed rectifier potassium current (I(ks)) in heart.	Potassium	105-114	ETS transcription factor ERG	Homo sapiens	38-42
20535583-2	2010	RESULTS: Matrine inhibited HERG potassium current in a dose-dependent manner, and the 50% inhibitory concentration (IC IC(50)) was 411+-23 mumol/L.	Potassium	32-41	potassium voltage-gated channel subfamily H member 2	Homo sapiens	27-31
20813867-7	2010	Furthermore, a potassium load, sodium depletion, and aldosterone infusion each significantly reduced miR-192 expression in the kidney.	Potassium	15-24	microRNA 192	Homo sapiens	101-108
20626758-0	2010	Effects of carvedilol on delayed rectifier and transient inactivating potassium currents in rat hippocampal CA1 neurons.	Potassium	70-79	carbonic anhydrase 1	Rattus norvegicus	108-111
20595684-7	2010	Instead, suppression of sEH activity seemed to be responsible for the 11,12-EET-mediated enhanced inhibition of ENaC in animals on a high-potassium diet.	Potassium	138-147	epoxide hydrolase 2	Rattus norvegicus	24-27
20595684-10	2010	In conclusion, high dietary potassium enhances the inhibitory effect of AA and 11,12-EET on ENaC by increasing CYP epoxygenase activity and decreasing sEH activity, respectively.	Potassium	28-37	epoxide hydrolase 2	Rattus norvegicus	151-154
20813867-8	2010	Taken together, these results suggest a miR-driven mechanism of gene regulation by aldosterone and a role for miR-192 in the regulation of sodium and potassium balance in the kidney.	Potassium	150-159	microRNA 192	Homo sapiens	110-117
20488163-2	2010	While Kv1.3 is responsible for the voltage-dependent potassium current in T-cells, in macrophages this K(+) current is generated by the association of Kv1.3 and Kv1.5.	Potassium	53-62	potassium voltage-gated channel subfamily A member 3	Homo sapiens	6-11
20970606-3	2010	OBJECTIVE: To evaluate the potassium and magnesium changes due to converting patients from CNIs to mTOR inhibitors.	Potassium	27-36	mechanistic target of rapamycin kinase	Homo sapiens	99-103
20558181-4	2010	These "cells" between mica sheets are filled with potassium ions, and they provide an environment in which: polymer entropy is low; cyclic wetting and drying can occur; molecules can evolve in isolated spaces and also migrate and ligate to form larger molecules.	Potassium	50-59	MHC class I polypeptide-related sequence A	Homo sapiens	22-26
20616716-1	2010	PURPOSE OF REVIEW: We integrate recent evidence that demonstrates the importance of the gastric (HKalpha1) and nongastric (HKalpha2)-containing hydrogen potassium adenosine triphosphatases (H,K-ATPases) on physiological function and their role in potassium (K), sodium (Na), and acid-base balance.	Potassium	153-162	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	123-131
20616305-0	2010	Mucosal potassium efflux mediated via Kcnn4 channels provides the driving force for electrogenic anion secretion in colon.	Potassium	8-17	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	38-43
20831751-10	2010	Reduced activity of Kir4.1 channels in astrocytes of D2 mice is associated with deficits in potassium and glutamate buffering.	Potassium	92-101	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	20-26
20570675-7	2010	In contrast, a significant decrease in postsynaptic baclofen-induced potassium currents was seen in SSADH KO mice.	Potassium	69-78	aldhehyde dehydrogenase family 5, subfamily A1	Mus musculus	100-105
20570675-9	2010	Finally, adenosine-induced potassium currents were also reduced in SSADH KO mice, which could suggest heterologous desensitization of the G-protein dependent effectors, leading to a reduction in G-protein coupled inwardly rectifying potassium (GIRK) channel responses.	Potassium	27-36	aldhehyde dehydrogenase family 5, subfamily A1	Mus musculus	67-72
20432466-3	2010	We find that M3GFP-BDNF induced to differentiate significantly accumulate BDNF and undergone to high potassium-mediated depolarization, show rapid BDNF recycle and activation of Trk receptors signaling.	Potassium	101-110	brain derived neurotrophic factor	Homo sapiens	13-23
20432466-3	2010	We find that M3GFP-BDNF induced to differentiate significantly accumulate BDNF and undergone to high potassium-mediated depolarization, show rapid BDNF recycle and activation of Trk receptors signaling.	Potassium	101-110	brain derived neurotrophic factor	Homo sapiens	19-23
20450907-6	2010	Furthermore, using [35S]GTPgammaS binding determination at CHO-halpha2B or CHO-halpha2A cell membranes and G protein coupled inwardly rectifying potassium (GIRK) current recordings in Xenopus oocytes expressing halpha2B, partial agonist activity of (+)8-OH-DPAT at the respective receptors was confirmed in these two different functional assays.	Potassium	145-154	potassium inwardly rectifying channel subfamily J member 3 L homeolog	Xenopus laevis	156-160
20557424-0	2010	Dual modulation of inward rectifier potassium currents in olfactory neuronal cells by promiscuous G protein coupling of the oxytocin receptor.	Potassium	36-45	oxytocin receptor	Homo sapiens	124-141
20720114-1	2010	Expressed metabotropic group 1 glutamate mGluR5 receptors and nucleotide P2Y1 receptors (P2Y1Rs) show promiscuous ion channel coupling in sympathetic neurons: their stimulation inhibits M-type [Kv7, K(M)] potassium currents and N-type (Ca(V)2.2) calcium currents (Kammermeier and Ikeda, 1999; Brown et al., 2000).	Potassium	205-214	glutamate receptor, ionotropic, kainate 1	Mus musculus	41-47
20720114-1	2010	Expressed metabotropic group 1 glutamate mGluR5 receptors and nucleotide P2Y1 receptors (P2Y1Rs) show promiscuous ion channel coupling in sympathetic neurons: their stimulation inhibits M-type [Kv7, K(M)] potassium currents and N-type (Ca(V)2.2) calcium currents (Kammermeier and Ikeda, 1999; Brown et al., 2000).	Potassium	205-214	purinergic receptor P2Y1	Homo sapiens	73-77
20600123-3	2010	We report solid-state NMR chemical shift fingerprints of two distinct conformations of the selectivity filter; significant changes are observed in the chemical shifts of key residues in the filter as the potassium ion concentration is changed from 50 mM to 1 muM.	Potassium	204-213	latexin	Homo sapiens	259-262
20600123-4	2010	Potassium ion titration studies reveal that the site-specific K(d) for K(+) binding at the key pore residue Val76 is on the order of approximately 7 muM and that a relatively high sample hydration is necessary to observe the low-K(+) conformer.	Potassium	0-9	latexin	Homo sapiens	149-152
20678632-6	2010	Cytochrome c complexed with DCH18C6 in the PEG-rich phase was quantitatively recovered into a salt-rich phase using K(2)SO(4) by ion exchange of potassium ion and cationic protein in the cationic protein complex with DCH18C6.	Potassium	145-154	cytochrome c, somatic	Homo sapiens	0-12
20678225-4	2010	Forced expression of KChIP1 in cultured hippocampal neurons increased the frequency of miniature inhibitory postsynaptic currents (mIPSCs), reduced paired pulse facilitation of autaptic IPSCs, and decreases potassium current density.	Potassium	207-216	potassium voltage-gated channel interacting protein 1	Homo sapiens	21-27
20678225-5	2010	Furthermore, genetic ablation of KChIP1 potentiated potassium current density in neurons and caused a robust enhancement of anxiety-like behavior in mice.	Potassium	52-61	Kv channel-interacting protein 1	Mus musculus	33-39
20333436-0	2010	Potassium and sodium transport in non-animal cells: the Trk/Ktr/HKT transporter family.	Potassium	0-9	neurotrophic receptor tyrosine kinase 1	Homo sapiens	56-59
20175205-3	2010	We therefore examined PrP effects on a suite of potassium (K(+)) conductances that govern excitability of basal forebrain neurons.	Potassium	48-57	prion protein	Rattus norvegicus	22-25
20439438-4	2010	TROX-1 preferentially inhibited potassium-triggered calcium influx through recombinant Ca(v)2.2 channels under depolarized conditions (IC(50) = 0.27 microM) compared with hyperpolarized conditions (IC(50) &gt; 20 microM).	Potassium	32-41	calcium channel, voltage-dependent, N type, alpha 1B subunit	Mus musculus	87-95
20434582-5	2010	As for other infections causing NRLP3 inflammasome assembly, caspase-1 activation in monocytes is triggered by potassium efflux and reactive oxygen species production.	Potassium	111-120	caspase 1	Homo sapiens	61-70
20424930-5	2010	Following our initial findings with platelet endothelial cell adhesion molecule (PECAM)-1, our studies have revealed a key role for potassium ion permeability in regulating integrin-dependent binding of apoptotic cells by macrophages and their subsequent response to proinflammatory stimuli.	Potassium	132-141	platelet and endothelial cell adhesion molecule 1	Homo sapiens	36-89
20175205-7	2010	PrP(106-126) application also evoked a depression of the delayed rectifier (I(K)) and transient outward (I(A)) potassium currents.	Potassium	111-120	prion protein	Rattus norvegicus	0-3
19850109-2	2010	AQP4 is a critical component of an integrated water and potassium homeostasis.	Potassium	56-65	aquaporin 4	Homo sapiens	0-4
20466422-5	2010	The presence of Gal at the concentrations of 10(-10) and 10(-8) M in the incubative media enriched in potassium ions excess was the cause of diminished AVP release from the NH and from the Hth-NH explant, respectively.	Potassium	102-111	galanin and GMAP prepropeptide	Rattus norvegicus	16-19
20026249-8	2010	Here, we critically discuss the experimental evidence concerning: (1) molecular and functional interplay of aquaporin 4, the major aquaporin protein in astroglial cells, with potassium and gap-junctional channels that are involved in extracellular potassium buffering.	Potassium	175-184	aquaporin 4	Homo sapiens	108-119
20442363-7	2010	Furthermore, Axl knockdown inhibits KS cell growth and invasion.	Potassium	36-38	AXL receptor tyrosine kinase	Homo sapiens	13-16
20442363-11	2010	Axl thus has a potential role in KS pathogenesis and is a candidate for prognostic and therapeutic investigations.	Potassium	33-35	AXL receptor tyrosine kinase	Homo sapiens	0-3
20109536-6	2010	Our transcriptional profiling of injured rat cords suggests that elevated AQP4-mediated water influx accompanies increased uptake of chloride and potassium ions which represents a protective astrocytic reaction to hypoxia.	Potassium	146-155	aquaporin 4	Rattus norvegicus	74-78
20399258-5	2010	Ka/Ks analysis indicates that the SPOPL genes are under functional constraints implicating biological functions.	Potassium	3-5	speckle type BTB/POZ protein like	Homo sapiens	34-39
20498229-2	2010	MiRP3 is found to co-localize with Kv4.2 subunits that contribute to cardiac transient outward potassium currents (I(to)).	Potassium	95-104	potassium voltage-gated channel subfamily E regulatory subunit 4	Homo sapiens	0-5
20498229-2	2010	MiRP3 is found to co-localize with Kv4.2 subunits that contribute to cardiac transient outward potassium currents (I(to)).	Potassium	95-104	potassium voltage-gated channel subfamily D member 2	Homo sapiens	35-40
20399767-11	2010	The increase of KCNE1/KCNQ1 ratio converted I(Ks) inhibition to I(Ks) activations.	Potassium	46-48	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	16-21
20399767-11	2010	The increase of KCNE1/KCNQ1 ratio converted I(Ks) inhibition to I(Ks) activations.	Potassium	46-48	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	22-27
20399767-11	2010	The increase of KCNE1/KCNQ1 ratio converted I(Ks) inhibition to I(Ks) activations.	Potassium	66-68	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	16-21
20399767-11	2010	The increase of KCNE1/KCNQ1 ratio converted I(Ks) inhibition to I(Ks) activations.	Potassium	66-68	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	22-27
20399767-12	2010	One to ten ratio of KCNE1 and KCNQ1 subunit is required for Rg(3) activation of I(Ks).	Potassium	82-84	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	20-25
20399767-12	2010	One to ten ratio of KCNE1 and KCNQ1 subunit is required for Rg(3) activation of I(Ks).	Potassium	82-84	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	30-35
20399767-15	2010	These results indicate that Rg(3)-induced activation of I(Ks) requires co-assembly of KCNQ1 and KCNE1 subunits and achieves this through interaction with residues K318 and V319 of KCNQ1 subunit.	Potassium	58-60	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	86-91
20399767-15	2010	These results indicate that Rg(3)-induced activation of I(Ks) requires co-assembly of KCNQ1 and KCNE1 subunits and achieves this through interaction with residues K318 and V319 of KCNQ1 subunit.	Potassium	58-60	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	96-101
20399767-15	2010	These results indicate that Rg(3)-induced activation of I(Ks) requires co-assembly of KCNQ1 and KCNE1 subunits and achieves this through interaction with residues K318 and V319 of KCNQ1 subunit.	Potassium	58-60	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	180-185
19874361-2	2010	Human herpesvirus 8 is associated with all epidemiological forms of KS and has been shown in vitro to induce the tyrosine receptor kinase c-Kit in infected cells.	Potassium	68-70	KIT proto-oncogene, receptor tyrosine kinase	Homo sapiens	138-143
19874361-3	2010	AIM: To investigate the expression of c-Kit in cases of classic KS and to clarify its association with clinicopathological parameters and HHV8 latency-associated nuclear antigen-1 expression.	Potassium	64-66	KIT proto-oncogene, receptor tyrosine kinase	Homo sapiens	38-43
19874361-9	2010	CONCLUSIONS: The results of our study show that in cases of classic KS there is a high rate of c-Kit immunoreactivity, but c-Kit expression does not show any correlation with HHV8 immunoreactivity.	Potassium	68-70	KIT proto-oncogene, receptor tyrosine kinase	Homo sapiens	95-100
20444939-0	2010	Adiponectin modulates excitability of rat paraventricular nucleus neurons by differential modulation of potassium currents.	Potassium	104-113	adiponectin, C1Q and collagen domain containing	Rattus norvegicus	0-11
20444939-9	2010	The results presented in this study suggest that adiponectin controls neuronal excitability through the modulation of different potassium conductances, effects which contribute to changes in excitability and action potential profiles responsible for peptidergic release into the circulation.	Potassium	128-137	adiponectin, C1Q and collagen domain containing	Rattus norvegicus	49-60
20348026-1	2010	BACKGROUND: Mutations in the KCNQ1 and human ether-a-go-go-related gene (HERG) genes cause the long QT syndromes, LQTS1 and LQTS2, due to reductions in the cardiac repolarizing I(Ks) and I(Kr) currents, respectively.	Potassium	179-181	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	29-34
20645688-5	2010	Management of the CTCL population requires vigilence to prevent infection with skin contaminants, and monitoring of potassium and magnesium, electrolytes found to be low in a large proportion of patients.	Potassium	116-125	TSPY like 2	Homo sapiens	18-22
20348026-1	2010	BACKGROUND: Mutations in the KCNQ1 and human ether-a-go-go-related gene (HERG) genes cause the long QT syndromes, LQTS1 and LQTS2, due to reductions in the cardiac repolarizing I(Ks) and I(Kr) currents, respectively.	Potassium	179-181	potassium voltage-gated channel subfamily H member 2	Homo sapiens	73-77
20359524-7	2010	N/OFQ hyperpolarized 25% of RAIC-PAG pyramidal neurons by enhancing inwardly rectifying potassium conductance via pertussis toxin-sensitive G(alphai/o).	Potassium	88-97	prepronociceptin	Homo sapiens	0-5
20143420-4	2010	We demonstrated that PGC-1alpha expression was down-regulated in cerebellar granule neurons(CGNs) after activation of the JNK/c-Jun pathway by potassium deprivation.	Potassium	143-152	PPARG coactivator 1 alpha	Homo sapiens	21-31
20143420-4	2010	We demonstrated that PGC-1alpha expression was down-regulated in cerebellar granule neurons(CGNs) after activation of the JNK/c-Jun pathway by potassium deprivation.	Potassium	143-152	mitogen-activated protein kinase 8	Homo sapiens	122-125
20143420-4	2010	We demonstrated that PGC-1alpha expression was down-regulated in cerebellar granule neurons(CGNs) after activation of the JNK/c-Jun pathway by potassium deprivation.	Potassium	143-152	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	126-131
20143420-5	2010	Overexpression of PGC-1alpha partially protected CGNs from potassium deprivation-induced apoptosis.	Potassium	59-68	PPARG coactivator 1 alpha	Homo sapiens	18-28
20143420-8	2010	In conclusion, these results suggest that down-expression of PGC-1alpha partially mediated by activation of JNK/c-Jun may be through the binding of c-Jun to the CRE site in the PGC-1alpha promoter, and it might be involved in potassium deprivation-induced apoptosis in CGNs.	Potassium	226-235	PPARG coactivator 1 alpha	Homo sapiens	61-71
20143420-8	2010	In conclusion, these results suggest that down-expression of PGC-1alpha partially mediated by activation of JNK/c-Jun may be through the binding of c-Jun to the CRE site in the PGC-1alpha promoter, and it might be involved in potassium deprivation-induced apoptosis in CGNs.	Potassium	226-235	mitogen-activated protein kinase 8	Homo sapiens	108-111
20143420-8	2010	In conclusion, these results suggest that down-expression of PGC-1alpha partially mediated by activation of JNK/c-Jun may be through the binding of c-Jun to the CRE site in the PGC-1alpha promoter, and it might be involved in potassium deprivation-induced apoptosis in CGNs.	Potassium	226-235	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	112-117
20143420-8	2010	In conclusion, these results suggest that down-expression of PGC-1alpha partially mediated by activation of JNK/c-Jun may be through the binding of c-Jun to the CRE site in the PGC-1alpha promoter, and it might be involved in potassium deprivation-induced apoptosis in CGNs.	Potassium	226-235	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	148-153
20143421-11	2010	In comparison, another compound, called ASK-2a, that protects cerebellar granule neurons against low-potassium-induced death inhibits GSK3 and p38 MAPK but not CDKs.	Potassium	101-110	glycogen synthase kinase 3 beta	Mus musculus	134-138
20348108-6	2010	Among 100 different growth conditions, those that decrease the membrane potential (high external potassium) or pH gradient (high external pH) caused a reduction in growth of the aha2 mutant compared with wild type.	Potassium	97-106	H[+]-ATPase 2	Arabidopsis thaliana	178-182
20412803-1	2010	The phosphatase calcineurin and the kinases Hal4/Hal5 regulate high-affinity potassium uptake in Saccharomyces cerevisiae through the Trk1 transporter.	Potassium	77-86	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	44-48
20412803-1	2010	The phosphatase calcineurin and the kinases Hal4/Hal5 regulate high-affinity potassium uptake in Saccharomyces cerevisiae through the Trk1 transporter.	Potassium	77-86	protein kinase HAL5	Saccharomyces cerevisiae S288C	49-53
20412803-1	2010	The phosphatase calcineurin and the kinases Hal4/Hal5 regulate high-affinity potassium uptake in Saccharomyces cerevisiae through the Trk1 transporter.	Potassium	77-86	Trk1p	Saccharomyces cerevisiae S288C	134-138
20224560-0	2010	Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt study.	Potassium	99-108	apelin receptor	Homo sapiens	46-49
20224560-0	2010	Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt study.	Potassium	99-108	angiotensin converting enzyme 2	Homo sapiens	61-65
20224560-0	2010	Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt study.	Potassium	99-108	apelin	Homo sapiens	39-45
20224560-2	2010	We examined the association of genetic variants in the apelin-APJ system and angiotensin-converting enzyme 2 (ACE2) with BP responses to potassium supplementation.	Potassium	137-146	apelin	Homo sapiens	55-61
20224560-2	2010	We examined the association of genetic variants in the apelin-APJ system and angiotensin-converting enzyme 2 (ACE2) with BP responses to potassium supplementation.	Potassium	137-146	angiotensin converting enzyme 2	Homo sapiens	77-108
20224560-2	2010	We examined the association of genetic variants in the apelin-APJ system and angiotensin-converting enzyme 2 (ACE2) with BP responses to potassium supplementation.	Potassium	137-146	angiotensin converting enzyme 2	Homo sapiens	110-114
20224560-6	2010	RESULTS: In women, SNP rs2235306 in the APLN gene was significantly associated with diastolic BP (DBP) response to potassium supplementation (P = 0.0009).	Potassium	115-124	apelin	Homo sapiens	40-44
20224560-8	2010	In men, SNP rs4646174 of the ACE2 gene was significantly associated with systolic BP (SBP), DBP, and mean arterial pressure (MAP) responses to potassium supplementation (P = 0.0001, P = 0.001, and P = 3.0 x 10(-6), respectively).	Potassium	143-152	angiotensin converting enzyme 2	Homo sapiens	29-33
20224560-10	2010	CONCLUSION: Our study indicates that genetic variation of APLN and ACE2 may influence BP response to potassium intake.	Potassium	101-110	apelin	Homo sapiens	58-62
20224560-10	2010	CONCLUSION: Our study indicates that genetic variation of APLN and ACE2 may influence BP response to potassium intake.	Potassium	101-110	angiotensin converting enzyme 2	Homo sapiens	67-71
20188695-2	2010	Recent studies performed using synthetic p13 and isolated mitochondria demonstrated that the protein triggers an inward potassium (K+) current and inner membrane depolarization.	Potassium	120-129	H3 histone pseudogene 6	Homo sapiens	41-44
20421639-10	2010	Furthermore, our results suggest that the lysosomal cathepsin B protease, the formation of reactive oxygen species, and the efflux of potassium are needed for beta-glucan-induced NLRP3 inflammasome activation.	Potassium	134-143	NLR family pyrin domain containing 3	Homo sapiens	179-184
19913547-2	2010	The co-assembly of the pore-forming human KCNQ1 alpha-subunits with the modulating hKCNE1 beta-subunits generates I(Ks)in vivo, explaining why mutations in the hKCNQ1 gene underlie the LQT1 form of congenital LQT.	Potassium	116-118	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	42-47
19913547-2	2010	The co-assembly of the pore-forming human KCNQ1 alpha-subunits with the modulating hKCNE1 beta-subunits generates I(Ks)in vivo, explaining why mutations in the hKCNQ1 gene underlie the LQT1 form of congenital LQT.	Potassium	116-118	putative potassium voltage-gated channel subfamily E member 1B	Homo sapiens	83-94
19913547-2	2010	The co-assembly of the pore-forming human KCNQ1 alpha-subunits with the modulating hKCNE1 beta-subunits generates I(Ks)in vivo, explaining why mutations in the hKCNQ1 gene underlie the LQT1 form of congenital LQT.	Potassium	116-118	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	160-166
19913547-2	2010	The co-assembly of the pore-forming human KCNQ1 alpha-subunits with the modulating hKCNE1 beta-subunits generates I(Ks)in vivo, explaining why mutations in the hKCNQ1 gene underlie the LQT1 form of congenital LQT.	Potassium	116-118	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	185-189
19913547-4	2010	Mutant subunits with this arginine substitution generated no or barely detectable currents in a homotetrameric condition, but did generate I(Ks)-like currents in association with hKCNE1.	Potassium	141-143	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	179-185
20357072-0	2010	Expression of neuronal nitric oxide synthase in rabbit carotid body glomus cells regulates large-conductance Ca2+-activated potassium currents.	Potassium	124-133	nitric oxide synthase, brain	Oryctolagus cuniculus	14-44
20051248-1	2010	Recent evidence shows that the auxiliary subunit KChIP2, which assembles with pore-forming Kv4-subunits, represents a new potential regulator of the cardiac calcium-independent transient outward potassium current (I(to)) density.	Potassium	195-204	potassium voltage-gated channel interacting protein 2	Rattus norvegicus	49-55
20354865-5	2010	Using transfected Chinese hamster ovary (CHO) cells to reconstitute Kv4 complex, we show that the pharmacological inhibition of DPP10 glycosylation by tunicamycin and neuraminidase affects transient outward potassium current (I (to)) kinetics.	Potassium	207-216	inactive dipeptidyl peptidase 10	Cricetulus griseus	128-133
20413648-0	2010	High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment and postgermination growth under low-potassium conditions.	Potassium	135-144	high affinity K+ transporter 5	Arabidopsis thaliana	45-51
20413648-0	2010	High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment and postgermination growth under low-potassium conditions.	Potassium	135-144	K+ transporter 1	Arabidopsis thaliana	56-60
20421371-8	2010	We conclude that S3 mutants of KCNQ1 cause LQTS predominantly through biophysical effects on the gating of I(Ks), but some mutants also show protein stability/trafficking defects, which explains why the kinetic gain-of-function mutation S209F causes LQT1.	Potassium	109-111	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	31-36
20303341-0	2010	Characterizing the persistent CA3 interneuronal spiking activity in elevated extracellular potassium in the young rat hippocampus.	Potassium	91-100	carbonic anhydrase 3	Rattus norvegicus	30-33
20346391-6	2010	CCL2 significantly lowered the net whole-cell potassium currents in neurons after CCD but not after CCI or SNL.	Potassium	46-55	C-C motif chemokine ligand 2	Rattus norvegicus	0-4
20377177-1	2010	Two-dimensional magic angle flipping (MAF) was employed to measure the Q((n)) distribution in a (29)Si-enriched potassium disilicate glass (K(2)O.2SiO(2)).	Potassium	112-121	MAF bZIP transcription factor	Homo sapiens	38-41
20388794-3	2010	Microsomal PGE2 synthase, PGE2, and its receptors (EP1, EP2, EP3, and EP4) were detected in KS lesions with the distinct staining of EP2/EP4 in KS lesions.	Potassium	92-94	prostaglandin E receptor 1	Homo sapiens	51-54
20388794-3	2010	Microsomal PGE2 synthase, PGE2, and its receptors (EP1, EP2, EP3, and EP4) were detected in KS lesions with the distinct staining of EP2/EP4 in KS lesions.	Potassium	92-94	prostaglandin E receptor 2	Homo sapiens	56-59
20388794-3	2010	Microsomal PGE2 synthase, PGE2, and its receptors (EP1, EP2, EP3, and EP4) were detected in KS lesions with the distinct staining of EP2/EP4 in KS lesions.	Potassium	92-94	prostaglandin E receptor 3	Homo sapiens	61-64
20388794-3	2010	Microsomal PGE2 synthase, PGE2, and its receptors (EP1, EP2, EP3, and EP4) were detected in KS lesions with the distinct staining of EP2/EP4 in KS lesions.	Potassium	92-94	prostaglandin E receptor 4	Homo sapiens	70-73
20388794-3	2010	Microsomal PGE2 synthase, PGE2, and its receptors (EP1, EP2, EP3, and EP4) were detected in KS lesions with the distinct staining of EP2/EP4 in KS lesions.	Potassium	144-146	prostaglandin E receptor 2	Homo sapiens	133-136
20388794-3	2010	Microsomal PGE2 synthase, PGE2, and its receptors (EP1, EP2, EP3, and EP4) were detected in KS lesions with the distinct staining of EP2/EP4 in KS lesions.	Potassium	144-146	prostaglandin E receptor 4	Homo sapiens	137-140
20056717-7	2010	The anti-miR-204-induced decrease in Kir7.1 protein levels suggests a signaling pathway that connects TGF-betaR2 and maintenance of potassium homeostasis.	Potassium	132-141	microRNA 204	Homo sapiens	9-16
20056717-7	2010	The anti-miR-204-induced decrease in Kir7.1 protein levels suggests a signaling pathway that connects TGF-betaR2 and maintenance of potassium homeostasis.	Potassium	132-141	potassium inwardly rectifying channel subfamily J member 13	Homo sapiens	37-43
20392939-3	2010	To test whether Kv1.1-potassium deficiency could underlie primary neurogenic cardiac dysfunction, we performed simultaneous video EEG-ECG recordings and found that Kcna1-null mice display potentially malignant interictal cardiac abnormalities, including a fivefold increase in atrioventricular (AV) conduction blocks, as well as bradycardia and premature ventricular contractions.	Potassium	22-31	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	16-21
20229012-5	2010	hERG channels were expressed in Xenopus laevis oocytes and HEK 293 cells, and potassium currents were recorded using patch clamp and two-electrode voltage clamp electrophysiology.	Potassium	78-87	ETS transcription factor ERG	Homo sapiens	0-4
20392939-3	2010	To test whether Kv1.1-potassium deficiency could underlie primary neurogenic cardiac dysfunction, we performed simultaneous video EEG-ECG recordings and found that Kcna1-null mice display potentially malignant interictal cardiac abnormalities, including a fivefold increase in atrioventricular (AV) conduction blocks, as well as bradycardia and premature ventricular contractions.	Potassium	22-31	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	164-169
20375134-1	2010	During neuronal activity astrocytes function to remove extracellular increases in potassium, which are largely mediated by the inwardly-rectifying potassium channel Kir4.1, and to take up excess glutamate via glutamate transporter 1, a glial-specific glutamate transporter.	Potassium	82-91	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	165-171
20089930-0	2010	Mitochondria-produced superoxide mediates angiotensin II-induced inhibition of neuronal potassium current.	Potassium	88-97	angiotensinogen	Homo sapiens	42-56
20375134-9	2010	These findings suggest that the neuroprotective benefits previously seen with 17beta-oestradiol after spinal cord injury may be in part due to increased Kir4.1 and glutamate transporter 1 expression in astrocytes leading to improved potassium and glutamate homeostasis.	Potassium	233-242	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	153-159
20583536-1	2010	Aldosterone plays an important role in blood pressure homeostasis, the regulation of circulating volume, and the maintenance of the sodium-potassium balance by binding to the mineralocorticoid receptor (MR).	Potassium	139-148	nuclear receptor subfamily 3 group C member 2	Homo sapiens	175-201
20132223-7	2010	Among various coactivators for PPARalpha, only steroid receptor coactivator (SRC)-3 level was higher in the KS-type.	Potassium	108-110	peroxisome proliferator activated receptor alpha	Rattus norvegicus	31-40
20132223-10	2010	EMSA supported the binding of these proteins to PPARalpha associated to the BE enhancer in CF-treated KS-type, but not in the NC-type.	Potassium	102-104	peroxisome proliferator activated receptor alpha	Rattus norvegicus	48-57
20299355-8	2010	Paradoxically, this led to increased urinary fluid velocity in potassium-adapted Kcnmb4-deficient mice compared with wild-type mice.	Potassium	63-72	potassium large conductance calcium-activated channel, subfamily M, beta member 4	Mus musculus	81-87
20583536-1	2010	Aldosterone plays an important role in blood pressure homeostasis, the regulation of circulating volume, and the maintenance of the sodium-potassium balance by binding to the mineralocorticoid receptor (MR).	Potassium	139-148	nuclear receptor subfamily 3 group C member 2	Homo sapiens	203-205
20436212-7	2010	Under AP clamp, peak repolarising current was significantly augmented for V307L KCNQ1 compared to WT KCNQ1 for both ventricular and atrial AP commands, consistent with an ability of the V307L mutation to increase repolarising I(Ks) in both regions.	Potassium	228-230	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	80-85
19996987-0	2010	Blood pressure response to potassium supplementation is associated with genetic variation in endothelin 1 and interactions with E selectin in rural Chinese.	Potassium	27-36	endothelin 1	Homo sapiens	93-105
19996987-0	2010	Blood pressure response to potassium supplementation is associated with genetic variation in endothelin 1 and interactions with E selectin in rural Chinese.	Potassium	27-36	selectin E	Homo sapiens	130-138
20003076-0	2010	Glucagon-like peptide-1 inhibits voltage-gated potassium currents in mouse nodose ganglion neurons.	Potassium	47-56	glucagon	Mus musculus	0-23
19996987-7	2010	RESULTS: Single SNP analysis identified significant associations for several SNPs in EDN1 with multiple measures of BP response to potassium supplementation.	Potassium	131-140	endothelin 1	Homo sapiens	85-89
19996987-10	2010	CONCLUSION: Our results implicate variability in EDN1 and SELE as genetic factors that influence BP response to potassium intake.	Potassium	112-121	endothelin 1	Homo sapiens	49-53
19996987-10	2010	CONCLUSION: Our results implicate variability in EDN1 and SELE as genetic factors that influence BP response to potassium intake.	Potassium	112-121	selectin E	Homo sapiens	58-62
19996987-11	2010	Although such epidemiological studies do not allow direct determination of physiologic mechanisms, our findings of joint effects identify EDN1 and SELE as targets for functional studies to determine their interactions in BP response to potassium intake.	Potassium	236-245	endothelin 1	Homo sapiens	138-142
20003076-10	2010	We identified a GLP-1 sensitive current whose reversal potential shifted in a depolarizing direction when extracellular potassium was increased.	Potassium	120-129	glucagon	Mus musculus	16-21
20170697-1	2010	Depolarization of cultured mouse cerebellar granule cells with potassium or kainate results in developmentally arrested state that includes down-regulation of GABA(A) receptor alpha1, alpha6 and beta2 subunit expression.	Potassium	63-72	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	Mus musculus	184-190
20170697-1	2010	Depolarization of cultured mouse cerebellar granule cells with potassium or kainate results in developmentally arrested state that includes down-regulation of GABA(A) receptor alpha1, alpha6 and beta2 subunit expression.	Potassium	63-72	hemoglobin, beta adult minor chain	Mus musculus	195-200
20003076-14	2010	CONCLUSIONS &amp; INFERENCES: These experiments indicate that GLP-1 receptor activation results in vagal afferent excitation, due at least in part to inhibition of sustained and inactivating potassium currents.	Potassium	191-200	glucagon-like peptide 1 receptor	Mus musculus	62-76
19902272-4	2010	Tissue-specific alterations of growth hormone and insulin-like growth factor I axis have been described in experimental models of potassium depletion.	Potassium	130-139	growth hormone 1	Homo sapiens	31-45
19902272-4	2010	Tissue-specific alterations of growth hormone and insulin-like growth factor I axis have been described in experimental models of potassium depletion.	Potassium	130-139	insulin-like growth factor 1	Rattus norvegicus	50-78
20100173-4	2010	We found that xCT was overexpressed in KS tissues and HHV-8-positive BCBL-1 cells.	Potassium	39-41	solute carrier family 7 member 11	Homo sapiens	14-17
19903464-0	2010	Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652.	Potassium	34-43	ETS transcription factor ERG	Homo sapiens	29-33
20100173-7	2010	These results suggest that 14-3-3beta is a downstream effector of xCT in KS to mediate the cell proliferation.	Potassium	73-75	solute carrier family 7 member 11	Homo sapiens	66-69
20043893-0	2010	Actions of bis(7)-tacrine and tacrine on transient potassium current in rat DRG neurons and potassium current mediated by K(V)4.2 expressed in Xenopus oocyte.	Potassium	92-101	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	122-129
20074622-0	2010	Inwardly rectifying potassium channel Kir4.1 is responsible for the native inward potassium conductance of satellite glial cells in sensory ganglia.	Potassium	20-29	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	38-44
20043893-3	2010	In the present study, the effect of bis(7)-tacrine was investigated on the K(V)4.2 encoded potassium currents expressed in Xenopus oocytes and the transient A-type potassium current (I(K(A))) on rat DRG neurons.	Potassium	91-100	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	75-82
20344995-5	2010	For NDI, the potassium sparing diuretic amiloride or a thiazide diuretic can improve polyuria.	Potassium	13-22	arginine vasopressin receptor 2	Homo sapiens	4-7
19277489-5	2010	In freshly isolated hippocampal pyramidal neurons, 54.25% of potassium current was inhibited by 20 microg/ml Gln49-PLA(2).	Potassium	61-70	phospholipase A2, group V	Mus musculus	115-120
20369755-9	2010	Some authors still recommend glucose-potassium-insulin infusions for all patients with type 1 diabetes.	Potassium	37-46	insulin	Homo sapiens	47-54
20185111-2	2010	Genetic variants in the KCNE1 gene, encoding for the beta-subunit (minK) of a slowly activated cardiac potassium channel (I(ks)), may impair myocardial repolarization.	Potassium	124-126	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	24-29
20139709-5	2010	In this study we used a novel approach to demonstrate that purified recombinant human KCNE1 protein (prKCNE1) modulates KCNQ1 channels heterologously expressed in Xenopus oocytes resulting in generation of I(Ks).	Potassium	208-210	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	86-91
20139709-5	2010	In this study we used a novel approach to demonstrate that purified recombinant human KCNE1 protein (prKCNE1) modulates KCNQ1 channels heterologously expressed in Xenopus oocytes resulting in generation of I(Ks).	Potassium	208-210	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	120-125
20339157-0	2010	Coronatine-insensitive 1 (COI1) mediates transcriptional responses of Arabidopsis thaliana to external potassium supply.	Potassium	103-112	RNI-like superfamily protein	Arabidopsis thaliana	0-24
19845787-5	2010	Physiological fluctuations of all NKAT regulators in blood, many known to be involved in migraine, are monitored by receptors on the luminal wall of brain CECs; signals are then transduced to their abluminal NKATs that alter brain extracellular sodium ([Na(+)](e)) and potassium ([K(+)](e)).	Potassium	269-278	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3	Homo sapiens	34-38
20052569-9	2010	SMC obtained from irradiated rats treated with hMSC demonstrated a significantly increased paxilline-sensitive component of outward potassium currents, indicating that BK(Ca) activity had been restored.	Potassium	132-141	musculin	Homo sapiens	47-51
20139158-0	2010	A peroxidase contributes to ROS production during Arabidopsis root response to potassium deficiency.	Potassium	79-88	peroxidase	Arabidopsis thaliana	2-12
20139158-1	2010	Reactive oxygen species (ROS) play an important role in root responses to potassium deprivation by regulating the expression of the high-affinity K(+) transporter gene AtHAK5 and other genes.	Potassium	74-83	high affinity K+ transporter 5	Arabidopsis thaliana	168-174
20139158-4	2010	RCI3 was found to be up-regulated upon potassium deprivation.	Potassium	39-48	Peroxidase superfamily protein	Arabidopsis thaliana	0-4
20139158-6	2010	These results suggested that RCI3 is involved in the production of ROS under potassium deprivation and that RCI3-mediated ROS production affects the regulation of AtHAK5 expression.	Potassium	77-86	Peroxidase superfamily protein	Arabidopsis thaliana	29-33
20139158-7	2010	This peroxidase appears to be another component of the low-potassium signal transduction pathway in Arabidopsis roots.	Potassium	59-68	peroxidase	Arabidopsis thaliana	5-15
20339157-0	2010	Coronatine-insensitive 1 (COI1) mediates transcriptional responses of Arabidopsis thaliana to external potassium supply.	Potassium	103-112	RNI-like superfamily protein	Arabidopsis thaliana	26-30
20112435-2	2010	But physicians" concerns about the risk of hyperkalemia (elevated serum potassium level), a potentially fatal adverse effect, may limit optimal management with ACE-inhibitors.	Potassium	72-81	angiotensin I converting enzyme	Homo sapiens	160-163
19895883-0	2010	Effect of melamine on potassium currents in rat hippocampal CA1 neurons.	Potassium	22-31	carbonic anhydrase 1	Rattus norvegicus	60-63
20390067-4	2010	Loss-of-function mutations in KCNH2, the gene encoding the cardiac ion channel that is responsible for the rapidly activating delayed rectifying potassium current, are linked to long-QT syndrome type 2 (LQT-2).	Potassium	145-154	potassium voltage-gated channel subfamily H member 2	Homo sapiens	30-35
20390067-4	2010	Loss-of-function mutations in KCNH2, the gene encoding the cardiac ion channel that is responsible for the rapidly activating delayed rectifying potassium current, are linked to long-QT syndrome type 2 (LQT-2).	Potassium	145-154	potassium voltage-gated channel subfamily H member 2	Homo sapiens	203-208
19437409-6	2010	However, release of glutamate and acetylcholine was decreased from the hippocampus in response to high-potassium treatment in the Cyp D(-/-) mice than in the wild-type mice.	Potassium	103-112	peptidylprolyl isomerase F (cyclophilin F)	Mus musculus	130-135
20029090-11	2010	Therefore, it is likely that potassium is the predominant MVC bound to HDAC8 in vivo.	Potassium	29-38	histone deacetylase 8	Homo sapiens	71-76
19907016-1	2010	KCNE1 associates with the pore-forming alpha-subunit KCNQ1 to generate the slow (I(Ks)) current in cardiac myocytes.	Potassium	83-85	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	0-5
19907016-1	2010	KCNE1 associates with the pore-forming alpha-subunit KCNQ1 to generate the slow (I(Ks)) current in cardiac myocytes.	Potassium	83-85	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	53-58
19907016-3	2010	We previously investigated a mutation in KCNE1, T58P/L59P, which causes severe attenuation of I(Ks).	Potassium	96-98	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	41-46
19965931-0	2010	ERRgamma regulates cardiac, gastric, and renal potassium homeostasis.	Potassium	47-56	estrogen-related receptor gamma	Mus musculus	0-8
19362017-8	2010	The divided insulin regimen was associated with significantly lower mean potassium levels within 2 hours before reperfusion of the graft compared with the conventional group (p &lt; 0.005).	Potassium	73-82	insulin	Homo sapiens	12-19
19362017-10	2010	CONCLUSIONS: The divided insulin dose regimen that specifically targets the risk factors for prereperfusion hyperkalemia is associated with significantly lower prereperfusion potassium and pre- and postreperfusion glucose levels and provides a useful alternative to the conventional large-bolus method in management of intraoperative hyperkalemia during liver transplantation.	Potassium	175-184	insulin	Homo sapiens	25-32
19965931-4	2010	Consistently, ERRgamma null animals die during the first 72 h of life with elevated serum potassium, reductions in key gastric acid production markers, and cardiac arrhythmia with prolonged QT intervals.	Potassium	90-99	estrogen-related receptor gamma	Mus musculus	14-22
19912566-0	2010	The AtNHX1 exchanger mediates potassium compartmentation in vacuoles of transgenic tomato.	Potassium	30-39	Na+/H+ exchanger 1	Arabidopsis thaliana	4-10
18804879-7	2010	The independent factors associated with a decreased serum potassium concentration were mean blood pressure (P&lt;0.0001), heart failure evaluated by log BNP (P=0.0164) and the use of diuretics (P=0.0232).	Potassium	58-67	natriuretic peptide B	Homo sapiens	153-156
20113033-1	2010	Fast potassium atoms donate an electron to CCl(3)NO(2) molecules to form K(+) ions and the negative ions O(-), Cl(-), NO(2) (-), CCl(3) (-), CCl(2)NO(2) (-), CCl(3)NO(-), and CCl(3)NO(2) (-).	Potassium	5-14	C-C motif chemokine ligand 3	Homo sapiens	43-49
20738248-4	2010	The drug-induced blockade of the hERG-related component of the potassium current is thought to be a major reason for drug-induced arrhythmias in humans.	Potassium	63-72	ETS transcription factor ERG	Homo sapiens	33-37
20057125-2	2010	We found that the AtKUP/HAK/KT9 gene from Arabidopsis thaliana was functionally expressed in a potassium transport-deficient Escherichia coli mutant.	Potassium	95-104	K+ uptake permease 9	Arabidopsis thaliana	28-31
20057125-3	2010	AtKUP/HAK/KT9 mediated potassium uptake as well as cesium transport.	Potassium	23-32	K+ uptake permease 9	Arabidopsis thaliana	10-13
20027486-0	2010	Role of 11beta-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure.	Potassium	64-73	hydroxysteroid 11-beta dehydrogenase 2	Rattus norvegicus	8-45
19485915-4	2010	Also, potassium supplement suppressed salt-induced insulin resistance.	Potassium	6-15	insulin	Homo sapiens	51-58
19485915-9	2010	Thus, it is possible that dietary potassium protects against salt-induced cardiovascular damage by the reduction of ROS generation and by central sympatholytic action and amelioration of insulin resistance induced through its antioxidant effect.	Potassium	34-43	insulin	Homo sapiens	187-194
20091480-1	2010	The role of the kidney in controlling and maintaining plasma potassium levels in the normal range requires the presence and activity of renal potassium channels, and their importance has been highlighted in patients with Bartter syndrome harboring mutations in the ROMK (Kir1.1, KCJN1) channel and hyperkalemia.	Potassium	61-70	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	265-269
20700417-2	2010	Promoter regions of C-myc and Bcl2 forming G-quadruplex structures are chemically synthesized and G-quadruplex structure is formed in presence of 100 mM potassium ion.	Potassium	153-162	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	20-25
20700417-2	2010	Promoter regions of C-myc and Bcl2 forming G-quadruplex structures are chemically synthesized and G-quadruplex structure is formed in presence of 100 mM potassium ion.	Potassium	153-162	BCL2 apoptosis regulator	Homo sapiens	30-34
19901197-0	2010	Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway.	Potassium	101-110	estrogen related receptor, alpha	Mus musculus	34-65
19646991-5	2010	Application of the WT NPPA peptide fragment produced similar changes in WT-I(Ks), and these were exaggerated with the mutant NPPA S64R peptide fragment.	Potassium	77-79	natriuretic peptide A	Homo sapiens	22-26
20030467-11	2010	CONCLUSION: Our data suggest that potassium should be monitored with particular caution when spironolactone is started in patients with heart failure who have evidence of elevated aldosterone levels, such as high diuretic requirements, or the NR3C2 215G allele.	Potassium	34-43	nuclear receptor subfamily 3 group C member 2	Homo sapiens	243-248
19509473-2	2009	The aim of the study was to compare, in the model of human MNL, the effect of potassium-sparing diuretics amiloride and canrenone, on the protein expression of p22phox, a NADPH-oxidase system subunit, that is a principal marker of production of superoxide anions.	Potassium	78-87	cytochrome b-245 alpha chain	Homo sapiens	160-167
20030467-8	2010	Patients with a greater potassium level elevation had a higher mean +/- SD aldosterone concentration (178 +/- 92 vs 102 +/- 57 pg/ml, p=0.007) and NR3C2 215G allele frequency (50% vs 22%, p&lt;0.01).	Potassium	24-33	nuclear receptor subfamily 3 group C member 2	Homo sapiens	147-152
20030467-10	2010	On regression analysis, factors predictive of potassium level increases greater than 0.5 mEq/L with spironolactone were aldosterone level greater than 150 pg/ml (odds ratio [OR] 30, 95% confidence interval [CI] 3.2-287] and NR3C2 215G carrier status (OR 17, 95% CI 1.6-167).	Potassium	46-55	nuclear receptor subfamily 3 group C member 2	Homo sapiens	224-229
19735700-4	2009	Potassium-induced depolarization effects were impaired by blockade of calcium entry through N and P/Q channels, as well as of CaMKII, but release was not affected by activators or inhibitors of the cAMP/PKA pathway (1-methyl-3-isobutylxanthine (IBMX), N6,2"-O-dibutyryladenosine 3",5"-cyclic monophosphate sodium salt (db-cAMP) or myristoyl PKA inhibitor peptide 14-22 (PKI(14-22)).	Potassium	0-9	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	126-132
19794143-0	2009	K(bg) and Kv1.3 channels mediate potassium efflux in the early phase of apoptosis in Jurkat T lymphocytes.	Potassium	33-42	potassium voltage-gated channel subfamily A member 3	Homo sapiens	10-15
28199518-0	2009	Physiological Genomics Identifies Estrogen-Related Receptor alpha as a Regulator of Renal Sodium and Potassium Homeostasis and the Renin-Angiotensin Pathway.	Potassium	101-110	estrogen related receptor alpha	Homo sapiens	34-65
19846661-4	2009	We have found that BMP-6, but not BMP-7, is able to block low potassium-mediated apoptosis in CGCs.	Potassium	62-71	bone morphogenetic protein 6	Homo sapiens	19-24
19805535-7	2009	By using LPS-primed macrophages as a model system, it was determined that IL-1beta secretion was dependent on caspase-1, potassium efflux, and the activity of serine proteases.	Potassium	121-130	interleukin 1 beta	Mus musculus	74-82
19828724-0	2009	Shaker and Shal mediate transient calcium-independent potassium current in a Drosophila flight motoneuron.	Potassium	54-63	Shaker cognate l	Drosophila melanogaster	11-15
19828724-5	2009	Pharmacological and genetic manipulations unravel the specific contributions of Shaker and Shal to the calcium independent transient A-type potassium currents.	Potassium	140-149	Shaker cognate l	Drosophila melanogaster	91-95
19828724-10	2009	Targeted knock down of Shaker or Shal channels each cause identical reduction in total potassium current amplitude as acute application of alpha-dendrotoxin or phrixotoxin-2, respectively.	Potassium	87-96	Shaker cognate l	Drosophila melanogaster	33-37
19726551-2	2009	Expression of Kv7.2/7.3 channels in human embryonic kidney (HEK) 293 cells produced a noninactivating potassium current characteristic of M current.	Potassium	102-111	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	14-19
19486916-0	2009	Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons.	Potassium	71-80	mitogen-activated protein kinase 8	Homo sapiens	29-32
19820116-3	2009	Using circular dichroism (CD), thermal denaturation and dimethyl sulfate (DMS) footprinting, we found that a single-stranded oligonucleotide with the sequence of the BCL2 G-rich region forms a potassium-stabilized G-quadruplex.	Potassium	193-202	BCL2 apoptosis regulator	Homo sapiens	166-170
19801679-11	2009	Functional studies demonstrated MYOCD-induced, iberiotoxin-sensitive potassium currents in porcine coronary SMCs.	Potassium	69-78	myocardin	Homo sapiens	32-37
19919977-5	2009	Compared with furosemide treatment alone, Ucn2+furosemide produced a further diuresis (P&lt;0.05), natriuresis (P&lt;0.05), and a sustained increase in creatinine excretion (P&lt;0.05) and clearance (P&lt;0.05), without additional potassium elimination.	Potassium	231-240	urocortin-2	Ovis aries	42-46
19919977-4	2009	Compared with time-matched controls, separate Ucn2 and furosemide administration significantly increased urine output (furosemide&gt;Ucn2), urine sodium (furosemide&gt;Ucn2), potassium (furosemide&gt;Ucn2), and creatinine excretion (Ucn2&gt;furosemide) and creatinine clearance (Ucn2&gt;furosemide).	Potassium	175-184	urocortin-2	Ovis aries	46-50
19738156-9	2009	Increasing dietary potassium content decreased urinary active TGF-beta in animals receiving the high-salt diet but did not change urinary active TGF-beta in animals receiving the low-salt diet.	Potassium	19-28	transforming growth factor, beta 1	Rattus norvegicus	62-70
19841541-1	2009	Renal outer medullary potassium (ROMK) channels are exquisitely regulated to adjust renal potassium excretion and maintain potassium balance.	Potassium	22-31	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	33-37
19841541-1	2009	Renal outer medullary potassium (ROMK) channels are exquisitely regulated to adjust renal potassium excretion and maintain potassium balance.	Potassium	90-99	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	33-37
19841541-3	2009	In renal disease, aberrant ROMK endocytosis may contribute to potassium retention and hyperkalemia.	Potassium	62-71	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	27-31
19841541-8	2009	In mice, the abundance of kidney ARH protein was modulated by dietary potassium and inversely correlated with changes in ROMK.	Potassium	70-79	low density lipoprotein receptor adaptor protein 1	Mus musculus	33-36
20030210-3	2009	AQP4 is a critical component of an integrated water and potassium homeostasis.	Potassium	56-65	aquaporin 4	Homo sapiens	0-4
19841541-9	2009	Furthermore, ARH-knockout mice exhibited an altered ROMK response to potassium intake.	Potassium	69-78	low density lipoprotein receptor adaptor protein 1	Mus musculus	13-16
19841541-9	2009	Furthermore, ARH-knockout mice exhibited an altered ROMK response to potassium intake.	Potassium	69-78	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	52-56
19675207-5	2009	IL-1beta release at a low TLO dose requires potassium efflux, calcium influx, and the activities of calcium-independent PLA(2), caspase-1, and cathepsin B.	Potassium	44-53	interleukin 1 beta	Mus musculus	0-8
19706730-1	2009	The renal outer medullary potassium channel (ROMK) is expressed in the kidney tubule and critically regulates sodium and potassium balance.	Potassium	26-35	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	45-49
19710010-7	2009	POSH decreased potassium currents, and the inhibitory effect of POSH on ROMK channels was dose-dependent.	Potassium	15-24	SH3 domain containing ring finger 1	Homo sapiens	0-4
21158050-1	2009	AIM: To study the effect of Nociceptin/orphanin FQ (N/OFQ) on transient outward potassium (I(A)) in rat cerebral cortical neurons and its kinetic mechanism.	Potassium	80-89	prepronociceptin	Rattus norvegicus	28-38
21158050-1	2009	AIM: To study the effect of Nociceptin/orphanin FQ (N/OFQ) on transient outward potassium (I(A)) in rat cerebral cortical neurons and its kinetic mechanism.	Potassium	80-89	prepronociceptin	Rattus norvegicus	39-50
19710010-7	2009	POSH decreased potassium currents, and the inhibitory effect of POSH on ROMK channels was dose-dependent.	Potassium	15-24	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	72-76
19710010-10	2009	Moreover, POSH still decreased the potassium current in oocytes injected with a ROMK1 mutant (R1Delta373-378), in which a clathrin-dependent tyrosine-based internalization signal residing between amino acid residues 373 and 378 is deleted.	Potassium	35-44	SH3 domain containing ring finger 1	Homo sapiens	10-14
19846714-6	2009	Potassium-evoked depolarization of spinal cord slices caused concentration-dependent release of CGRP.	Potassium	0-9	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	96-100
19624107-3	2009	Although both surfaces are hydrophilic, our study shows that hydration of potassium ions on the mica surface has a strong influence on the water structure and solvation force response of confined water.	Potassium	74-83	MHC class I polypeptide-related sequence A	Homo sapiens	96-100
19809515-9	2009	Our results reveal that Dp71 is crucially implicated in the maintenance of potassium homeostasis, in transmembraneous water transport, and in the Muller cell-mediated regulation of retinal vascular permeability.	Potassium	75-84	dystrophin, muscular dystrophy	Mus musculus	24-28
19549558-5	2009	Specific neutralization of neurotrophic factor activity demonstrated that serum and potassium deprivation-induced Akt-mediated neuroprotection and caspase-3-dependent apoptosis were mainly modulated by IGF-1.	Potassium	84-93	AKT serine/threonine kinase 1	Homo sapiens	114-117
19549558-5	2009	Specific neutralization of neurotrophic factor activity demonstrated that serum and potassium deprivation-induced Akt-mediated neuroprotection and caspase-3-dependent apoptosis were mainly modulated by IGF-1.	Potassium	84-93	insulin like growth factor 1	Homo sapiens	202-207
19549558-6	2009	These data suggest that of the many neuroprotective factors secreted by ASC, IGF-1 is the major factor that mediates protection against serum and potassium deprivation-induced CGN apoptosis.	Potassium	146-155	insulin like growth factor 1	Homo sapiens	77-82
19458126-2	2009	Because of the central role that ROMK plays in the regulation of salt and potassium homeostasis, considerable efforts have been invested in understanding the underlying molecular mechanisms.	Potassium	74-83	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	33-37
19635485-1	2009	Inwardly rectifying potassium channel 2.3 (Kir2.3) is specifically targeted on the basolateral membranes of epithelial and neuronal cells, and it thus plays an important role in maintaining potassium homeostasis.	Potassium	20-29	potassium inwardly rectifying channel subfamily J member 4	Homo sapiens	43-49
19513770-8	2009	The positive wave is assigned to 5-HT3A receptors in the free membrane that drive a potassium outward current through the adherent membrane.	Potassium	84-93	5-hydroxytryptamine receptor 3A	Homo sapiens	33-39
19656910-9	2009	Sirolimus treatment reduced expression of NKCC2, and this was accompanied by greater urinary excretion of sodium, potassium, and magnesium.	Potassium	114-123	solute carrier family 12 member 1	Rattus norvegicus	42-47
19627466-10	2009	The contractile responses to high potassium were significantly decreased in the DHEA/DHEAS-pretreated strips, compared with the DHEA/DHEAS-nontreated strips.	Potassium	34-43	sulfotransferase family 2A member 1	Homo sapiens	85-90
19615985-0	2009	Serum potassium in renal impairment: at what concentration of estimated GFR does it rise?	Potassium	6-15	Rap guanine nucleotide exchange factor 5	Homo sapiens	72-75
19789539-2	2009	report that inhibition of the enzyme 11beta-hydroxysteroid dehydrogenase type 2 by glycyrrhetinic acid, the active compound of licorice, reduces serum potassium concentration and the frequency of hyperkalemia, possibly by enhancing intestinal potassium loss.	Potassium	151-160	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	37-79
19789539-2	2009	report that inhibition of the enzyme 11beta-hydroxysteroid dehydrogenase type 2 by glycyrrhetinic acid, the active compound of licorice, reduces serum potassium concentration and the frequency of hyperkalemia, possibly by enhancing intestinal potassium loss.	Potassium	243-252	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	37-79
19627466-10	2009	The contractile responses to high potassium were significantly decreased in the DHEA/DHEAS-pretreated strips, compared with the DHEA/DHEAS-nontreated strips.	Potassium	34-43	sulfotransferase family 2A member 1	Homo sapiens	133-138
19826169-4	2009	In this article the authors review the literature on the relationship between SGCs and nociception and present evidence that changes in SGC potassium ion buffering capacity and glutamate recycling can lead to neuropathic pain-like behavior in animal models.	Potassium	140-149	sarcoglycan beta	Homo sapiens	78-81
19415909-1	2009	Air-cleaved mica surfaces exhibit a high density of nanometer or micrometer size particles that have been ascribed to potassium carbonate formed as a reaction product of carbonaceous gases with potassium ions.	Potassium	118-127	MHC class I polypeptide-related sequence A	Homo sapiens	12-16
19792989-9	2009	Significant elevations were noted in fasting serum glucose (mean +/- SD 3.42 +/- 10.38 mg/dl, p&lt;0.0001) and plasma insulin (2.35 +/- 9.47 microU/ml, p&lt;0.0001) levels, and a significant reduction in serum potassium level (0.30 +/- 0.44 mEq/L, p&lt;0.0001) was noted.	Potassium	210-219	insulin	Homo sapiens	118-125
19477239-5	2009	Using patch-clamp recordings of dopaminergic neurons in slices of the rat substantia nigra, we observed that a prolonged exposure (&gt;8 min) to 10 nM CCL2 significantly increases the membrane resistance of dopaminergic neurons by closure of background channels mainly selective to potassium ions.	Potassium	282-291	C-C motif chemokine ligand 2	Rattus norvegicus	151-155
19661927-9	2009	RESULTS: At 2 years, systolic and diastolic blood pressure (SBP/DBP) had decreased by 5.9/2.8 mm Hg (4.7/3.6%) in the added-potassium-and-calcium group and by 5.8/1.0 mm Hg (4.8/1.4%) in the salt-restricted group; the values rose in the control group by 1.3/2.3 mm Hg (1.1/1.8%).	Potassium	124-133	D-box binding PAR bZIP transcription factor	Homo sapiens	64-67
19463845-11	2009	In isolated kidney, the PLA(2) from B. caissarum increased the perfusion pressure, renal vascular resistance, urinary flow, glomerular filtration rate, and sodium, potassium and chloride levels of excretion.	Potassium	164-173	phospholipase A2	Apis mellifera	24-29
19666591-0	2009	Crystal structure of the sodium-potassium pump (Na+,K+-ATPase) with bound potassium and ouabain.	Potassium	32-41	dynein axonemal heavy chain 8	Homo sapiens	55-61
19460776-0	2009	Connexin43 in cardiomyocyte mitochondria contributes to mitochondrial potassium uptake.	Potassium	70-79	gap junction protein, beta 1	Mus musculus	0-10
19497810-2	2009	However, the application of Hodgkin-Huxley-type models does not produce such adaptation, which occurs over time periods on the order of 100 ms. We describe our development of a computational ANF axon model that incorporates a time-changing external potassium concentration ( [K(+)](ext)) that depends on potassium currents produced by active nodal channel activity.	Potassium	249-258	natriuretic peptide A	Homo sapiens	191-194
19497810-2	2009	However, the application of Hodgkin-Huxley-type models does not produce such adaptation, which occurs over time periods on the order of 100 ms. We describe our development of a computational ANF axon model that incorporates a time-changing external potassium concentration ( [K(+)](ext)) that depends on potassium currents produced by active nodal channel activity.	Potassium	304-313	natriuretic peptide A	Homo sapiens	191-194
19404674-0	2009	Angiotensin II type 1 receptor mediates partially hyposmotic-induced increase of I (Ks) current in guinea pig atrium.	Potassium	84-86	type-1 angiotensin II receptor	Cavia porcellus	0-30
19458124-0	2009	Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney.	Potassium	0-9	solute carrier family 38, member 3	Mus musculus	116-121
19707551-2	2009	In particular, activated microglial cells can express sets of Kv subunits which sustain delayed rectifying potassium currents (Kdr) and modulate differently microglia proliferation and ability to release mediators.	Potassium	107-116	kinase insert domain receptor	Homo sapiens	127-130
19409452-0	2009	Endothelin-1 raises excitability and reduces potassium currents in sensory neurons.	Potassium	45-54	endothelin 1	Rattus norvegicus	0-12
19509299-4	2009	AKT1-mediated potassium absorption from K(+)-depleted soil was shown to depend on the calcium-sensing proteins CBL1/9 and their interacting kinase CIPK23.	Potassium	14-23	K+ transporter 1	Arabidopsis thaliana	0-4
19509299-4	2009	AKT1-mediated potassium absorption from K(+)-depleted soil was shown to depend on the calcium-sensing proteins CBL1/9 and their interacting kinase CIPK23.	Potassium	14-23	calcineurin B-like protein 1	Arabidopsis thaliana	111-117
19509299-6	2009	Although at submillimolar external potassium an intrinsic K(+) sensor reduces AKT1 channel cord conductance, loss of cytosolic potassium is not completely abolished under these conditions.	Potassium	35-44	K+ transporter 1	Arabidopsis thaliana	78-82
19509299-7	2009	Depending on channel activity and the actual potassium gradients, this channel-mediated K(+) loss results in impaired plant growth in the atkc1 mutant.	Potassium	45-54	potassium channel protein	Arabidopsis thaliana	138-143
19458124-0	2009	Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney.	Potassium	0-9	solute carrier family 38, member 3	Mus musculus	123-130
19424712-6	2009	Inhibiting cellular endocytosis by depleting cellular potassium or by acidifying the cytosol blocked the internalization of Tie2 in response to Ang1.	Potassium	54-63	TEK receptor tyrosine kinase	Homo sapiens	124-128
19493963-0	2009	Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency.	Potassium	110-119	solute carrier family 34 member 1	Rattus norvegicus	69-77
19493963-0	2009	Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency.	Potassium	110-119	solute carrier family 34 member 3	Rattus norvegicus	79-87
19493963-0	2009	Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency.	Potassium	110-119	solute carrier family 20 member 2	Rattus norvegicus	93-98
19424712-6	2009	Inhibiting cellular endocytosis by depleting cellular potassium or by acidifying the cytosol blocked the internalization of Tie2 in response to Ang1.	Potassium	54-63	angiopoietin 1	Homo sapiens	144-148
19464262-2	2009	A member of the family of potassium-dependent sodium/calcium exchangers, NCKX3 (SLC24A3) plays a critical role in the transport of an intracellular calcium and potassium ion in exchange for four extracellular sodium ions.	Potassium	26-35	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	73-78
19609280-0	2009	Variations in the WNK1 gene modulates the effect of dietary intake of sodium and potassium on blood pressure determination.	Potassium	81-90	WNK lysine deficient protein kinase 1	Homo sapiens	18-22
19609280-6	2009	Our data support the hypothesis that part of the variation in blood pressure response to dietary sodium and potassium intake among individuals can be explained by variations in the WNK1 gene.	Potassium	108-117	WNK lysine deficient protein kinase 1	Homo sapiens	181-185
19477186-6	2009	We solved another hSPS1 structure with potassium ions at the active sites.	Potassium	39-48	selenophosphate synthetase 1	Homo sapiens	18-23
19464262-2	2009	A member of the family of potassium-dependent sodium/calcium exchangers, NCKX3 (SLC24A3) plays a critical role in the transport of an intracellular calcium and potassium ion in exchange for four extracellular sodium ions.	Potassium	26-35	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	80-87
19464262-2	2009	A member of the family of potassium-dependent sodium/calcium exchangers, NCKX3 (SLC24A3) plays a critical role in the transport of an intracellular calcium and potassium ion in exchange for four extracellular sodium ions.	Potassium	160-169	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	73-78
19464262-2	2009	A member of the family of potassium-dependent sodium/calcium exchangers, NCKX3 (SLC24A3) plays a critical role in the transport of an intracellular calcium and potassium ion in exchange for four extracellular sodium ions.	Potassium	160-169	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	Mus musculus	80-87
19623261-2	2009	For instance, Kv12.2 (ELK2, KCNH3) channels are highly expressed in the cerebral cortex and hippocampus, and although they are most likely to contribute to resting potassium conductance, surprisingly little is known about their function or regulation.	Potassium	164-173	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	14-20
19623261-2	2009	For instance, Kv12.2 (ELK2, KCNH3) channels are highly expressed in the cerebral cortex and hippocampus, and although they are most likely to contribute to resting potassium conductance, surprisingly little is known about their function or regulation.	Potassium	164-173	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	22-26
19623261-2	2009	For instance, Kv12.2 (ELK2, KCNH3) channels are highly expressed in the cerebral cortex and hippocampus, and although they are most likely to contribute to resting potassium conductance, surprisingly little is known about their function or regulation.	Potassium	164-173	potassium voltage-gated channel, subfamily H (eag-related), member 3	Mus musculus	28-33
19556540-9	2009	We conclude that the majority of the hypertension of Kcnmb1(-/-) is due to aldosteronism, resulting from renal potassium retention and hyperkalemia.	Potassium	111-120	potassium large conductance calcium-activated channel, subfamily M, beta member 1	Mus musculus	53-59
19521339-2	2009	In heart, assembly of Kv7.1 pore-forming subunits with KCNE1 beta subunits generates the repolarizing K(+) current I(KS).	Potassium	117-119	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	22-27
19521339-2	2009	In heart, assembly of Kv7.1 pore-forming subunits with KCNE1 beta subunits generates the repolarizing K(+) current I(KS).	Potassium	117-119	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	55-60
19416975-5	2009	Here we show that high extracellular potassium opens pannexin channels leading to caspase-1 activation in primary neurons and astrocytes.	Potassium	37-46	caspase 1	Homo sapiens	82-91
19478075-4	2009	Consistent with results in cultured cells, high potassium-evoked ACh release in hippocampal slices from young GRK5 knock-out mice was significantly reduced compared with wild type littermates, and this reduced ACh release was also fully corrected by methoctramine.	Potassium	48-57	G protein-coupled receptor kinase 5	Mus musculus	110-114
19420113-1	2009	The H(+)-K(+)-ATPase alpha(2) (HKalpha2) gene of the renal collecting duct and distal colon plays a central role in potassium and acid-base homeostasis, yet its transcriptional control remains poorly characterized.	Potassium	116-125	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	4-29
19420113-1	2009	The H(+)-K(+)-ATPase alpha(2) (HKalpha2) gene of the renal collecting duct and distal colon plays a central role in potassium and acid-base homeostasis, yet its transcriptional control remains poorly characterized.	Potassium	116-125	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	31-39
20409966-0	2009	A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study.	Potassium	96-105	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	2-7
19617705-0	2009	Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation.	Potassium	14-23	potassium voltage-gated channel subfamily H member 2	Homo sapiens	47-51
19617705-6	2009	In this study, HERG block by quinidine and cisapride was assessed in extracellular solutions of calcium, potassium, rubidium, cesium and tetraethylammonium (TEA) using two-electrode voltage clamping of Xenopus oocytes.	Potassium	105-114	potassium voltage-gated channel subfamily H member 2	Homo sapiens	15-19
19617705-7	2009	Consistent with previous reports we show that increases in extracellular potassium reduce HERG block by quinidine and cisapride.	Potassium	73-82	potassium voltage-gated channel subfamily H member 2	Homo sapiens	90-94
19617705-9	2009	These results demonstrate that at lower extracellular potassium concentrations, the permeant ion is almost exclusively responsible for the reduction in quinidine and cisapride block of HERG due to increases in extracellular potassium.	Potassium	54-63	potassium voltage-gated channel subfamily H member 2	Homo sapiens	185-189
19617705-9	2009	These results demonstrate that at lower extracellular potassium concentrations, the permeant ion is almost exclusively responsible for the reduction in quinidine and cisapride block of HERG due to increases in extracellular potassium.	Potassium	224-233	potassium voltage-gated channel subfamily H member 2	Homo sapiens	185-189
20409966-6	2009	Our results suggest that the SNP rs17238540 in the HMGCR is associated with the BP response to urinary sodium: potassium ratio, the magnitude of the association differing according to possession of the G allele.	Potassium	111-120	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	51-56
19376127-7	2009	These effects were largely reversed by intracellular dialysis of anti-ClC-2 antibody, which significantly inhibited Cl,ir current but not other pacemaker currents, including the hyperpolarization-activated non-selective cationic "funny" current (I(f)), the L-type Ca(2+) currents (I(Ca,L)), the slowly-activating delayed rectifier I(Ks) and the volume-regulated outwardly-rectifying Cl(-) current (I(Cl,vol)).	Potassium	333-335	chloride channel protein 2	Cavia porcellus	70-75
20144338-1	2009	BACKGROUND: Adrenaline release and excess insulin during hypoglycemia stimulate the uptake of potassium from the bloodstream, causing low plasma potassium (hypokalemia).	Potassium	94-103	insulin	Homo sapiens	42-49
20144338-1	2009	BACKGROUND: Adrenaline release and excess insulin during hypoglycemia stimulate the uptake of potassium from the bloodstream, causing low plasma potassium (hypokalemia).	Potassium	145-154	insulin	Homo sapiens	42-49
20144338-5	2009	An insulin-induced uptake of potassium was modeled using a negative exponential function, and an adrenaline-induced uptake of potassium was modeled as a linear function.	Potassium	29-38	insulin	Homo sapiens	3-10
19372190-2	2009	Angiotensin II (AngII) and elevated extracellular potassium concentrations ([K(+)](e)), the prime physiologic regulators of aldosterone secretion from adrenal glomerulosa cells, activate phospholipase D (PLD) in these cells.	Potassium	50-59	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	204-207
19285119-3	2009	Exposure of isolated sensory neurons in culture to GDNF, neurturin, and artemin enhanced the capsaicin-stimulated release of immunoreactive calcitonin gene-related peptide (iCGRP) two- to threefold, but did not increase potassium-stimulated release of iCGRP.	Potassium	220-229	glial cell line derived neurotrophic factor	Mus musculus	51-55
19639589-0	2009	Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons.	Potassium	46-55	dihydropyrimidinase like 4	Homo sapiens	18-31
19433335-0	2009	Angiotensin II increases excitability and inhibits a transient potassium current in vagal primary sensory neurons.	Potassium	63-72	angiotensinogen	Rattus norvegicus	0-14
19493694-1	2009	Deficiency of mineral nutrients such as nitrate, phosphate, potassium and sulphate strongly affects the type and amount of metabolites produced by crops with knock-on effects on nutritional quality of the crop, its processing properties and disease resistance.	Potassium	60-69	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	147-151
19501014-0	2009	Potassium nutrition, sodium toxicity, and calcium signaling: connections through the CBL-CIPK network.	Potassium	0-9	Cbl proto-oncogene	Homo sapiens	85-88
18623077-0	2009	In vitro study on influence of nano particles of CuO on CA1 pyramidal neurons of rat hippocampus potassium currents.	Potassium	97-106	carbonic anhydrase 1	Rattus norvegicus	56-59
18623077-1	2009	The effects of nano particles of CuO on voltage-dependent potassium currents were studied in acutely isolated CA1 pyramidal neurons of rat hippocampus using the whole-cell patch-clamp techniques.	Potassium	58-67	carbonic anhydrase 1	Rattus norvegicus	110-113
19348785-6	2009	G314S, co-expressed with WT KCNQ1 and KCNE1, suppressed I(ks) currents in a dominant-negative manner, which is consistent with long QT syndrome in the members of the Chinese family carrying G314S KCNQ1 mutation.	Potassium	58-60	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	28-33
19348785-6	2009	G314S, co-expressed with WT KCNQ1 and KCNE1, suppressed I(ks) currents in a dominant-negative manner, which is consistent with long QT syndrome in the members of the Chinese family carrying G314S KCNQ1 mutation.	Potassium	58-60	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	38-43
19348785-6	2009	G314S, co-expressed with WT KCNQ1 and KCNE1, suppressed I(ks) currents in a dominant-negative manner, which is consistent with long QT syndrome in the members of the Chinese family carrying G314S KCNQ1 mutation.	Potassium	58-60	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	196-201
19295169-0	2009	Inhibition of Kv1.3 potassium current by phosphoinositides and stromal-derived factor-1alpha in Jurkat T cells.	Potassium	20-29	potassium voltage-gated channel subfamily A member 3	Homo sapiens	14-19
19476648-0	2009	NF-kappaB mediated enhancement of potassium currents by the chemokine CXCL1/growth related oncogene in small diameter rat sensory neurons.	Potassium	34-43	C-X-C motif chemokine ligand 1	Rattus norvegicus	70-75
19237518-5	2009	Asc-dependent caspase-1 activation was inhibited by high extracellular potassium levels, whereas Ipaf-dependent activation was unaffected by potassium treatment.	Potassium	71-80	steroid sulfatase	Mus musculus	0-3
19420697-0	2009	Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate at different potassium ionic levels.	Potassium	104-113	branched chain keto acid dehydrogenase kinase	Homo sapiens	14-64
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	32-34	WNK lysine deficient protein kinase 1	Mus musculus	35-39
19307466-0	2009	Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease.	Potassium	23-32	renin	Homo sapiens	52-57
19307466-7	2009	Our study suggests that dual renin-angiotensin-aldosterone blockade may impair extrarenal/transcellular potassium disposition in addition to reducing potassium excretion in humans with renal impairment, and that acute changes in dynamic potassium handling are predictive of chronic changes in ambulatory potassium concentration with dual renin-angiotensin-aldosterone blockade.	Potassium	104-113	renin	Homo sapiens	29-34
19307466-7	2009	Our study suggests that dual renin-angiotensin-aldosterone blockade may impair extrarenal/transcellular potassium disposition in addition to reducing potassium excretion in humans with renal impairment, and that acute changes in dynamic potassium handling are predictive of chronic changes in ambulatory potassium concentration with dual renin-angiotensin-aldosterone blockade.	Potassium	150-159	renin	Homo sapiens	29-34
19307466-7	2009	Our study suggests that dual renin-angiotensin-aldosterone blockade may impair extrarenal/transcellular potassium disposition in addition to reducing potassium excretion in humans with renal impairment, and that acute changes in dynamic potassium handling are predictive of chronic changes in ambulatory potassium concentration with dual renin-angiotensin-aldosterone blockade.	Potassium	150-159	renin	Homo sapiens	29-34
19307466-7	2009	Our study suggests that dual renin-angiotensin-aldosterone blockade may impair extrarenal/transcellular potassium disposition in addition to reducing potassium excretion in humans with renal impairment, and that acute changes in dynamic potassium handling are predictive of chronic changes in ambulatory potassium concentration with dual renin-angiotensin-aldosterone blockade.	Potassium	150-159	renin	Homo sapiens	29-34
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	138-140	WNK lysine deficient protein kinase 1	Mus musculus	83-87
19244242-9	2009	Mutations of two phenylalanine residues known to be critical for autoinhibitory function of AID abolish the ability of the AID region of KS-WNK1 to antagonize L-WNK1.	Potassium	137-139	WNK lysine deficient protein kinase 1	Mus musculus	140-144
19244242-9	2009	Mutations of two phenylalanine residues known to be critical for autoinhibitory function of AID abolish the ability of the AID region of KS-WNK1 to antagonize L-WNK1.	Potassium	137-139	WNK lysine deficient protein kinase 1	Mus musculus	161-165
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	32-34	WNK lysine deficient protein kinase 1	Mus musculus	83-87
19244242-13	2009	Thus, KS-WNK1 is an important physiological regulator of renal K(+) excretion, likely through its effects on the ROMK1 channel.	Potassium	6-8	WNK lysine deficient protein kinase 1	Mus musculus	9-13
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	32-34	WNK lysine deficient protein kinase 1	Mus musculus	83-87
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	32-34	WNK lysine deficient protein kinase 1	Mus musculus	83-87
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	138-140	WNK lysine deficient protein kinase 1	Mus musculus	35-39
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	138-140	WNK lysine deficient protein kinase 1	Mus musculus	83-87
19244242-8	2009	We reported that two regions of KS-WNK1(1-253) are involved in the antagonism of L-WNK1; one includes the first 30 amino acids unique for KS-WNK1 encoded by the alternatively spliced initiating exon 4A, and the other is equivalent to the autoinhibitory domain (AID) of L-WNK1.	Potassium	138-140	WNK lysine deficient protein kinase 1	Mus musculus	83-87
19343045-7	2009	Functional analyses revealed consistent loss-of-function effects of mutant KCNA5 proteins on the ultrarapidly activating delayed rectifier potassium currents.	Potassium	139-148	potassium voltage-gated channel subfamily A member 5	Homo sapiens	75-80
20120472-16	2009	The potassium and copper combination used with cadmium concentration reduced catalase activity while peroxidase activity was promoted.	Potassium	4-13	peroxidase 1	Zea mays	101-111
19255142-9	2009	Taken together, our findings provide evidence that potassium deprivation-induced neuronal apoptosis is mediated by concurrent upregulation of c-Jun/ATF2 heterodimerization and downregulation of c-Fos expression.	Potassium	51-60	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	142-147
19255142-9	2009	Taken together, our findings provide evidence that potassium deprivation-induced neuronal apoptosis is mediated by concurrent upregulation of c-Jun/ATF2 heterodimerization and downregulation of c-Fos expression.	Potassium	51-60	activating transcription factor 2	Homo sapiens	148-152
19255142-9	2009	Taken together, our findings provide evidence that potassium deprivation-induced neuronal apoptosis is mediated by concurrent upregulation of c-Jun/ATF2 heterodimerization and downregulation of c-Fos expression.	Potassium	51-60	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	194-199
19096086-7	2009	Contrasting with these data, patients with CLCNKB had the lowest potassium (P = 0.006 versus KCNJ1 and P = 0.034 versus SLC12A1) and chloride plasma concentrations (P = 0.039 versus KCNJ1 and P = 0.024 versus SLC12A1) and the highest bicarbonataemia (P = 0.026 versus KCNJ1 and P = 0.014 versus SLC12A1).	Potassium	65-74	chloride voltage-gated channel Kb	Homo sapiens	43-49
19385061-3	2009	Correspondingly, hippocampal slices from Tsc1(GFAP)CKO mice have increased extracellular potassium concentration in response to stimulation.	Potassium	89-98	TSC complex subunit 1	Mus musculus	41-45
19385061-3	2009	Correspondingly, hippocampal slices from Tsc1(GFAP)CKO mice have increased extracellular potassium concentration in response to stimulation.	Potassium	89-98	glial fibrillary acidic protein	Mus musculus	46-50
19385061-5	2009	Furthermore, treatment with a mammalian target of rapamycin inhibitor reverses the deficient Cx43 expression and impaired potassium buffering.	Potassium	122-131	mechanistic target of rapamycin kinase	Homo sapiens	30-59
19385061-6	2009	These findings suggest that Tsc1 inactivation in astrocytes causes defects in astrocytic gap junction coupling and potassium clearance, which may contribute to epilepsy in Tsc1(GFAP)CKO mice.	Potassium	115-124	TSC complex subunit 1	Mus musculus	28-32
19385061-6	2009	These findings suggest that Tsc1 inactivation in astrocytes causes defects in astrocytic gap junction coupling and potassium clearance, which may contribute to epilepsy in Tsc1(GFAP)CKO mice.	Potassium	115-124	glial fibrillary acidic protein	Mus musculus	177-181
19233158-0	2009	Rapid component I(Kr) of cardiac delayed rectifier potassium currents in guinea-pig is inhibited by alpha(1)-adrenoreceptor activation via protein kinase A and protein kinase C-dependent pathways.	Potassium	51-60	Prkca	Cavia porcellus	160-176
19435876-8	2009	Significantly, potassium ions and compounds that stabilize the G-quadruplex and i-motif structures have an inhibitory effect on NM23-H2 DNA-binding activity.	Potassium	15-24	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	128-135
19244476-6	2009	In the present study we show that R-roscovitine blocks HERG potassium current (human embryonic kidney-293 cells stably expressing HERG) at clinically relevant concentrations.	Potassium	60-69	potassium voltage-gated channel subfamily H member 2	Homo sapiens	55-59
19351862-9	2009	Patch-clamp recordings in normal trophoblasts treated with estradiol exhibited potassium currents resembling Eag1 channel activity.	Potassium	79-88	potassium voltage-gated channel subfamily H member 1	Homo sapiens	109-113
19232322-4	2009	zERG channels conduct rapidly activating and inactivating potassium currents.	Potassium	58-67	ETS transcription factor ERG	Danio rerio	0-4
19218243-7	2009	We conclude that PDE4D3, like protein kinase A and protein phosphatase 1, is recruited to the I(Ks) channel via AKAP-9 and contributes to its critical regulation by cAMP.	Potassium	96-98	A kinase (PRKA) anchor protein (yotiao) 9	Mus musculus	112-118
19355940-9	2009	CaSR also mediates the acute adverse renal effects of hypercalcemia, which include a reduced sodium, potassium and water reabsorption.	Potassium	101-110	calcium sensing receptor	Homo sapiens	0-4
18231119-6	2009	Frassetto"s method was used to calculate the estimated NEAP from the diet"s protein to potassium ratio.	Potassium	87-96	dual specificity phosphatase 26	Homo sapiens	55-59
18752977-6	2009	Insulin sensitivity was assessed using a hyperinsulinemic euglycemic clamp and body composition by computed tomography (CT) scans and from total body potassium, K(40).	Potassium	150-159	insulin	Homo sapiens	0-7
19393126-1	2009	Gap junction protein connexin43 (Cx43), encoded by the GJA1 gene, is the most abundant connexin in the cardiovascular system and was reported as a crucial factor maintaining cardiac electrical conduction, as well as having a very important function in facilitating the recycling of potassium ions from hair cells in the cochlea back into the cochlear endolymph during auditory transduction processes.	Potassium	282-291	gap junction protein alpha 1	Homo sapiens	21-31
19393126-1	2009	Gap junction protein connexin43 (Cx43), encoded by the GJA1 gene, is the most abundant connexin in the cardiovascular system and was reported as a crucial factor maintaining cardiac electrical conduction, as well as having a very important function in facilitating the recycling of potassium ions from hair cells in the cochlea back into the cochlear endolymph during auditory transduction processes.	Potassium	282-291	gap junction protein alpha 1	Homo sapiens	33-37
19393126-1	2009	Gap junction protein connexin43 (Cx43), encoded by the GJA1 gene, is the most abundant connexin in the cardiovascular system and was reported as a crucial factor maintaining cardiac electrical conduction, as well as having a very important function in facilitating the recycling of potassium ions from hair cells in the cochlea back into the cochlear endolymph during auditory transduction processes.	Potassium	282-291	gap junction protein alpha 1	Homo sapiens	55-59
19306396-0	2009	Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome.	Potassium	42-51	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	6-11
19166858-9	2009	Overall, this work demonstrates for the first time that SUR2/Kir6.1 channels represent a significant potassium conductance in ventricular fibroblasts which may be activated in physio-pathological conditions and which may impact on fibroblast proliferation and function.	Potassium	101-110	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	Mus musculus	56-60
19166858-9	2009	Overall, this work demonstrates for the first time that SUR2/Kir6.1 channels represent a significant potassium conductance in ventricular fibroblasts which may be activated in physio-pathological conditions and which may impact on fibroblast proliferation and function.	Potassium	101-110	potassium inwardly-rectifying channel, subfamily J, member 8	Mus musculus	61-67
19356694-0	2009	Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry.	Potassium	72-81	AKT serine/threonine kinase 1	Rattus norvegicus	125-128
19181803-3	2009	In silico analyses reveal the presence of genes encoding four possible potassium uptake systems in the genome of Sinorhizobium meliloti 1021: Kup1, Kup2, Trk, and Kdp.	Potassium	71-80	potassium transporter Kup	Sinorhizobium meliloti 1021	142-146
19181803-3	2009	In silico analyses reveal the presence of genes encoding four possible potassium uptake systems in the genome of Sinorhizobium meliloti 1021: Kup1, Kup2, Trk, and Kdp.	Potassium	71-80	potassium transporter Kup	Sinorhizobium meliloti 1021	148-152
19181803-6	2009	The other three systems, especially Kup1, are also relevant during the osmotic adaptation of the cell, and the relative importance of the Kdp system increases at low potassium concentrations.	Potassium	166-175	potassium transporter Kup	Sinorhizobium meliloti 1021	36-40
19002489-0	2009	Human Kir2.1 channel carries a transient outward potassium current with inward rectification.	Potassium	49-58	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	6-12
19279535-2	2009	Since plasma renin activity is invariably elevated in Bartter syndrome, the availability of the direct renin inhibitor aliskiren should lead to the ability to maintain potassium levels without utilizing large doses of oral potassium.	Potassium	168-177	renin	Homo sapiens	103-108
19181671-4	2009	An apple alpha-farnesene synthase (MdAFS1), which has a dependence upon potassium (K(+)), was used to identify active site regions that may be important for M(+) binding.	Potassium	72-81	(E,E)-alpha-farnesene synthase	Malus domestica	9-33
19181671-4	2009	An apple alpha-farnesene synthase (MdAFS1), which has a dependence upon potassium (K(+)), was used to identify active site regions that may be important for M(+) binding.	Potassium	72-81	(E,E)-alpha-farnesene synthase	Malus domestica	35-41
19213956-2	2009	Here, we investigated the interaction between the MAGUK protein SAP97 and cardiac Kv4.2/3 channels, which account for a large part of the outward potassium current, I(to), in heart.	Potassium	146-155	discs large MAGUK scaffold protein 1	Homo sapiens	64-69
19213956-2	2009	Here, we investigated the interaction between the MAGUK protein SAP97 and cardiac Kv4.2/3 channels, which account for a large part of the outward potassium current, I(to), in heart.	Potassium	146-155	potassium voltage-gated channel subfamily D member 2	Homo sapiens	82-87
19197240-4	2009	By using potassium permanganate probing and differential scanning calorimetry, we reveal that the basic domain of TRF2 induces structural changes to the junction.	Potassium	9-18	telomeric repeat binding factor 2	Homo sapiens	114-118
19289641-13	2009	CONCLUSIONS: AT downregulates SAN HCN2/4 and minK subunit expression, along with the corresponding currents I(f) and I(Ks).	Potassium	119-121	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Canis lupus familiaris	34-38
19167866-0	2009	Lack of potassium current in W309R mutant KCNQ3 channel causing benign familial neonatal convulsions (BFNC).	Potassium	8-17	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	42-47
18814934-1	2009	To verify the possible involvement of lipids and several other compounds including hydrogen peroxide (H(2)O(2)) and glyceraldehyde-3-phosphate dehydrogenase (G3PDH) in the response of Hordeum vulgare to early potassium deprivation, plants were grown in hydroponic conditions for 30d with a modified Hewitt nutrient solution containing 3mM K(+).	Potassium	209-218	LOC548217	Hordeum vulgare	158-163
19281748-9	2009	When thiopental infusion was suddenly stopped, the potassium level increased to 8.9 mmol/l, which required quick administration of calcium gluconate and infusion of glucose solution mixed with regular insulin.	Potassium	51-60	insulin	Homo sapiens	201-208
19167866-4	2009	We found a lack of potassium current in W309R mutant KCNQ3 and KCNQ2 channels, which can explain the hyper-excitability of CNS in patients with BFNC.	Potassium	19-28	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	53-58
19167866-3	2009	In this study, potassium currents were recorded from HEK293 cells expressing both W309R mutant KCNQ3 and wild type KCNQ2 channels.	Potassium	15-24	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	95-100
19167866-3	2009	In this study, potassium currents were recorded from HEK293 cells expressing both W309R mutant KCNQ3 and wild type KCNQ2 channels.	Potassium	15-24	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	115-120
19148726-4	2009	Here, we investigated the arrhythmia phenotype of mice with targeted deletions of KCNE1 and KCNH2 genes which encode for minK/IsK and Merg1 (mouse homolog of human ERG) proteins resulting in loss of function of I(Ks) and I(Kr), respectively.	Potassium	213-215	potassium voltage-gated channel, Isk-related subfamily, member 1	Mus musculus	82-87
19073823-1	2009	The cortical collecting duct (CCD), which is involved in renal potassium (K) excretion, expresses cytochrome P450 (CYP)-epoxygenase.	Potassium	63-72	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	98-113
19073823-1	2009	The cortical collecting duct (CCD), which is involved in renal potassium (K) excretion, expresses cytochrome P450 (CYP)-epoxygenase.	Potassium	63-72	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	115-118
19286753-1	2009	INTRODUCTION: Central administration of angiotensin II (Ang II) is known to reduce urinary volume and to increase sodium and potassium excretion.	Potassium	125-134	angiotensinogen	Rattus norvegicus	40-54
19286753-1	2009	INTRODUCTION: Central administration of angiotensin II (Ang II) is known to reduce urinary volume and to increase sodium and potassium excretion.	Potassium	125-134	angiotensinogen	Rattus norvegicus	56-62
19286753-7	2009	CONCLUSION: This study demonstrates that increases of urinary sodium and potassium excretion elicited by central administration of Ang II are mediated by NAD(P)H oxidase- dependent production of superoxide and protein kinase C activation in conscious hydrated rats.	Potassium	73-82	angiotensinogen	Rattus norvegicus	131-137
19148726-4	2009	Here, we investigated the arrhythmia phenotype of mice with targeted deletions of KCNE1 and KCNH2 genes which encode for minK/IsK and Merg1 (mouse homolog of human ERG) proteins resulting in loss of function of I(Ks) and I(Kr), respectively.	Potassium	213-215	potassium voltage-gated channel, subfamily H (eag-related), member 2	Mus musculus	92-97
19005738-4	2009	GDNF secretion was augmented by stimulation with high potassium, while it was inhibited by treatment with either tunicamycin, an inhibitor of protein glycosylation, or brefeldin A, a disturbing factor of ER-Golgi transport.	Potassium	54-63	glial cell derived neurotrophic factor	Homo sapiens	0-4
19128153-2	2009	The reactions of 1a with 4 equiv of the potassium salts of arenethiolates in ethanol produced a series of dinuclear nickel thiolate complexes Ni(dadt(Et))Ni(SAr)(2) (Ar = Ph (2a), p-Tol (2b), 2,4,6-triisopropylphenyl (Tip) (2c)) in good yields.	Potassium	40-49	sarcosine dehydrogenase	Homo sapiens	157-160
19124472-6	2009	Here we demonstrate using a biotin-switch assay that NO induced S-nitrosylation of the alpha-subunit of the I(Ks) channel, KCNQ1, at Cys(445) in the C terminus.	Potassium	110-112	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	123-128
19135504-1	2009	Orexin (hypocretin) peptides are known to depolarize rat thalamic paraventricular nucleus (PVT) neurons by suppression of one or more undefined potassium conductances.	Potassium	144-153	hypocretin neuropeptide precursor	Rattus norvegicus	0-6
19103158-0	2009	Allosteric regulation of human poly(A)-specific ribonuclease by cap and potassium ions.	Potassium	72-81	poly(A)-specific ribonuclease	Homo sapiens	31-60
19103158-2	2009	We found that PARN is an allosteric enzyme, and potassium ions and the cap analogue were effectors with binding sites located at the RRM domain.	Potassium	48-57	poly(A)-specific ribonuclease	Homo sapiens	14-18
19190240-7	2009	The expression of High-Affinity K(+) Transporter5 was used as a marker of potassium deprivation and was found to be dependent on ethylene signaling.	Potassium	74-83	high affinity K+ transporter 5	Arabidopsis thaliana	18-49
19159406-18	2009	Electrophysiological testing revealed low-affinity inhibition of the potassium current through hERG channels expressed in HEK293 cells (IC(50) = 171 microM oxycodone).	Potassium	69-78	ETS transcription factor ERG	Homo sapiens	95-99
19187341-4	2009	In the latter responses, the hyperpolarization of the smooth muscle cells is evoked either via electrical coupling through myo-endothelial gap junctions or by potassium ions, which by accumulating in the intercellular space activate the inwardly rectifying potassium channel Kir2.1 and/or the Na(+)/K(+)-ATPase.	Potassium	159-168	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	275-281
19190240-8	2009	In the ethylene insensitive2-1 (ein2-1) mutant, the ethylene-mediated low potassium responses were not completely eliminated, suggesting that some potassium deprivation-induced responses are either ethylene independent or EIN2 independent.	Potassium	147-156	NRAMP metal ion transporter family protein	Arabidopsis thaliana	32-36
19190240-8	2009	In the ethylene insensitive2-1 (ein2-1) mutant, the ethylene-mediated low potassium responses were not completely eliminated, suggesting that some potassium deprivation-induced responses are either ethylene independent or EIN2 independent.	Potassium	74-83	NRAMP metal ion transporter family protein	Arabidopsis thaliana	32-36
19190240-8	2009	In the ethylene insensitive2-1 (ein2-1) mutant, the ethylene-mediated low potassium responses were not completely eliminated, suggesting that some potassium deprivation-induced responses are either ethylene independent or EIN2 independent.	Potassium	147-156	NRAMP metal ion transporter family protein	Arabidopsis thaliana	222-226
19046944-7	2009	OPA1 cleavage occurs concurrently with mitochondrial fragmentation and cytochrome c release in CGNs deprived of depolarizing potassium (5K condition).	Potassium	125-134	OPA1, mitochondrial dynamin like GTPase	Rattus norvegicus	0-4
19590188-10	2009	All three mutations reduced KCNQ1/KCNE1 channel currents in a dominant-negative manner when the mutants were coexpressed with wt subunits suggesting reduced I(Ks) as the molecular basis of LQT1.	Potassium	159-161	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	28-33
19050695-3	2009	It is well documented that TGF-beta receptors are endocytosed via clathrin-coated vesicles as TGF-beta endocytosis can be blocked by potassium depletion and the GTPase-deficient dynamin K44A mutant.	Potassium	133-142	transforming growth factor beta 1	Homo sapiens	27-35
19050695-3	2009	It is well documented that TGF-beta receptors are endocytosed via clathrin-coated vesicles as TGF-beta endocytosis can be blocked by potassium depletion and the GTPase-deficient dynamin K44A mutant.	Potassium	133-142	transforming growth factor beta 1	Homo sapiens	94-102
19590188-10	2009	All three mutations reduced KCNQ1/KCNE1 channel currents in a dominant-negative manner when the mutants were coexpressed with wt subunits suggesting reduced I(Ks) as the molecular basis of LQT1.	Potassium	159-161	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	34-39
19590188-10	2009	All three mutations reduced KCNQ1/KCNE1 channel currents in a dominant-negative manner when the mutants were coexpressed with wt subunits suggesting reduced I(Ks) as the molecular basis of LQT1.	Potassium	159-161	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	189-193
19089330-5	2009	On the molecular level, cGKI substrates fulfill various cellular functions regulating e.g. the intracellular calcium and potassium concentration, the calcium sensitivity, and the organisation of the intracellular cytoskeleton.	Potassium	121-130	protein kinase cGMP-dependent 1	Homo sapiens	24-28
19710528-6	2009	Using pharmacological, biophysical and molecular approaches, we demonstrate that Kv1.3 and Kir2.1 channels underlie outward and inward rectifying potassium currents, respectively.	Potassium	146-155	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	81-86
19710528-6	2009	Using pharmacological, biophysical and molecular approaches, we demonstrate that Kv1.3 and Kir2.1 channels underlie outward and inward rectifying potassium currents, respectively.	Potassium	146-155	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	91-97
19270440-0	2009	Development of skeletal muscle sodium and potassium currents in zebrafish sofa potato mutants.	Potassium	42-51	cholinergic receptor, nicotinic, delta (muscle)	Danio rerio	74-85
19270440-4	2009	We find that in both red and white muscle fibers, sop(-/-) mutants are able to support normal potassium current development during early stages of development [1-3 days post fertilization (dpf)], but at 6 dpf the potassium current density is significantly smaller than that in their phenotypically wild-type siblings (sop(+/?)).	Potassium	94-103	cholinergic receptor, nicotinic, delta (muscle)	Danio rerio	50-53
19270440-4	2009	We find that in both red and white muscle fibers, sop(-/-) mutants are able to support normal potassium current development during early stages of development [1-3 days post fertilization (dpf)], but at 6 dpf the potassium current density is significantly smaller than that in their phenotypically wild-type siblings (sop(+/?)).	Potassium	213-222	cholinergic receptor, nicotinic, delta (muscle)	Danio rerio	50-53
20201386-3	2009	In the present work we have studied the effects of TRPM8 channel agonist, menthol, on the contractions of the smooth muscle strips of the epididimal and prostatic portions of the rat vas deferens evoked by potassium rich (KCl) Krebs solution and by muscarinic or adrenergic agonists carbachol (CCh) or noradrenalin (Nor).	Potassium	206-215	arginine vasopressin	Rattus norvegicus	183-186
19390218-8	2009	PWD during HD was significantly correlated with predialysis systolic and diastolic blood pressure (r = 0.42, p = 0.037, and r = 0.59, p = 0.002, respectively) and predialysis serum potassium level (r = 0.44, p = 0.031).	Potassium	181-190	ATPase copper transporting beta	Homo sapiens	0-3
18930828-5	2009	N/OFQ hyperpolarized CeA(M)-PAG projection neurons by enhancing inwardly rectifying potassium conductance.	Potassium	84-93	prepronociceptin	Homo sapiens	0-5
19202345-12	2009	We conclude that increased expression of NCC, ENaC subunits, and ROMK contributed to distal potassium secretion leading to enhanced potassium excretion, which may explain the hypokalemia resulting from LP feeding.	Potassium	92-101	solute carrier family 12 member 3	Rattus norvegicus	41-44
19202345-12	2009	We conclude that increased expression of NCC, ENaC subunits, and ROMK contributed to distal potassium secretion leading to enhanced potassium excretion, which may explain the hypokalemia resulting from LP feeding.	Potassium	92-101	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	46-50
19202345-12	2009	We conclude that increased expression of NCC, ENaC subunits, and ROMK contributed to distal potassium secretion leading to enhanced potassium excretion, which may explain the hypokalemia resulting from LP feeding.	Potassium	132-141	solute carrier family 12 member 3	Rattus norvegicus	41-44
19202345-12	2009	We conclude that increased expression of NCC, ENaC subunits, and ROMK contributed to distal potassium secretion leading to enhanced potassium excretion, which may explain the hypokalemia resulting from LP feeding.	Potassium	132-141	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	46-50
19390218-12	2009	High diastolic blood pressure and serum potassium level before HD and ultrafiltration amount may predict prolonged PWD during HD.	Potassium	40-49	ATPase copper transporting beta	Homo sapiens	115-118
19749353-4	2009	It revealed that TLS especially bound to single stranded human telomeric DNA in the presence of potassium ion while it was not able to bind double stranded human telomeric DNA and single stranded human telomeric DNA in the presence of sodium ion.	Potassium	96-105	FUS RNA binding protein	Homo sapiens	17-20
18536934-10	2009	Potassium access from the lumen depends on activation of a K and Cl conductance via a KCNQ1/KCNE2 complex and Clic6.	Potassium	0-9	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	92-97
19567544-10	2009	Even potassium decreased from 4.0 +/- 0.3 to 3.4 +/- 0.4 mmol l(-1) after initiation of cardiopulmonary bypass.	Potassium	5-14	L1 cell adhesion molecule	Mus musculus	62-67
18536934-10	2009	Potassium access from the lumen depends on activation of a K and Cl conductance via a KCNQ1/KCNE2 complex and Clic6.	Potassium	0-9	chloride intracellular channel 6	Homo sapiens	110-115
18536934-10	2009	Potassium access from the lumen depends on activation of a K and Cl conductance via a KCNQ1/KCNE2 complex and Clic6.	Potassium	0-9	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	86-91
18798873-10	2009	Taken together, our results indicate that CBL-CIPK networks are responsible not only for stress responses and potassium shortage, but also for nitrate sensing.	Potassium	110-119	Cbl proto-oncogene	Homo sapiens	42-45
19319195-2	2009	We used zebrafish as a model organism to study the functions of Ka/Ks-predicted novel human exons, which were identified from a comparative evolutionary genomics analysis.In this study, a novel gene, designated as puf-A, was cloned and functionally characterized, and its homologs in zebrafish, mouse, and human were identified as one of the three homolog clusters which were consisted of 14 related proteins with Puf repeats.	Potassium	67-69	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	214-217
19319195-2	2009	We used zebrafish as a model organism to study the functions of Ka/Ks-predicted novel human exons, which were identified from a comparative evolutionary genomics analysis.In this study, a novel gene, designated as puf-A, was cloned and functionally characterized, and its homologs in zebrafish, mouse, and human were identified as one of the three homolog clusters which were consisted of 14 related proteins with Puf repeats.	Potassium	67-69	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	414-417
19187600-0	2008	High extracellular potassium ion concentration attenuates the blockade action of ketanserin on Kv1.3 channels expressed in xenopus oocytes.	Potassium	19-28	potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog	Xenopus laevis	95-100
19347040-0	2009	Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion.	Potassium	88-97	WNK lysine deficient protein kinase 1	Homo sapiens	21-25
19347040-4	2009	We found multiple variants to be associated with systolic blood pressure, SBP (7/28 tSNPs min-p = 0.0005), diastolic blood pressure, DBP (7/28 tSNPs min-p = 0.002) and 24 hour urinary potassium excretion (10/28 tSNPs min-p = 0.0004).	Potassium	184-193	D-box binding PAR bZIP transcription factor	Homo sapiens	133-136
19187600-8	2008	CONCLUSIONS: KT is a weak blocker of Kv1.3 channels at different concentrations of extracellular potassium and binds to the intracellular side of the channel pore.	Potassium	97-106	potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog	Xenopus laevis	37-42
19052238-2	2008	In the case of hypokalemic periodic paralysis, mutations of one of the outermost two gating charges in the S4 voltage sensor in domain II of the Na(V)1.4 alpha subunit induce gating pore current, resulting in a leak of sodium or protons through the voltage sensor that causes depolarization, sodium overload, and contractile failure correlated with low serum potassium.	Potassium	359-368	sodium voltage-gated channel alpha subunit 4	Rattus norvegicus	145-153
19052238-3	2008	Potassium-sensitive normokalemic periodic paralysis (NormoPP) is caused by mutations in the third gating charge in domain II of the Na(V)1.4 channel.	Potassium	0-9	sodium voltage-gated channel alpha subunit 4	Rattus norvegicus	132-140
19053274-4	2008	Our biophysical experiments indicate that the c-MYC quadruplex under physiological conditions is stable and dominates the quadruplex-WC duplex equilibrium in both sodium and potassium buffers.	Potassium	174-183	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	46-51
18854171-1	2008	Aquaporin-4 (AQP4) is expressed in the perivascular and subpial astrocytes end-feet in mammalian brain, and plays a critical component of an integrated water and potassium homeostasis.	Potassium	162-171	aquaporin 4	Homo sapiens	0-11
18854171-1	2008	Aquaporin-4 (AQP4) is expressed in the perivascular and subpial astrocytes end-feet in mammalian brain, and plays a critical component of an integrated water and potassium homeostasis.	Potassium	162-171	aquaporin 4	Homo sapiens	13-17
18986164-1	2008	The excitatory amino acid carrier EAAC1 belongs to a family of glutamate transporters that use the electrochemical transmembrane gradients of sodium and potassium to mediate uphill transport of glutamate into the cell.	Potassium	153-162	solute carrier family 1 member 1	Homo sapiens	34-39
18854423-2	2008	In rodent and bovine adrenal glomerulosa cells, this background potassium current is provided by a two-pore loop potassium (K2P) channel: largely TASK-3 in the rat and TREK-1 in the cow.	Potassium	64-73	keratin 76	Homo sapiens	124-127
18854423-2	2008	In rodent and bovine adrenal glomerulosa cells, this background potassium current is provided by a two-pore loop potassium (K2P) channel: largely TASK-3 in the rat and TREK-1 in the cow.	Potassium	64-73	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	168-174
18854423-9	2008	This suggests that human adrenal glomerulosa cells may utilize both of these K2P channels for their background potassium current.	Potassium	111-120	keratin 76	Homo sapiens	77-80
19075634-4	2008	The regulation of I(Ca,L) and I(Ks) occurs via the non-genomic pathway involving sequential activation of c-Src, PI3-kinase, Akt, and eNOS and resultant release of nitric oxide (NO), which occur in the caveolae/lipid raft domain.	Potassium	32-34	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	106-111
19075634-4	2008	The regulation of I(Ca,L) and I(Ks) occurs via the non-genomic pathway involving sequential activation of c-Src, PI3-kinase, Akt, and eNOS and resultant release of nitric oxide (NO), which occur in the caveolae/lipid raft domain.	Potassium	32-34	AKT serine/threonine kinase 1	Homo sapiens	125-128
18703633-7	2008	Apelin-13 decreases basal (by 78%; P &lt; 0.05; n = 6) and potassium-stimulated (by 57%; P &lt; 0.05; n = 6) vasopressin release but had no effect on somatodendritic oxytocin release.	Potassium	59-68	apelin	Rattus norvegicus	0-6
18703633-7	2008	Apelin-13 decreases basal (by 78%; P &lt; 0.05; n = 6) and potassium-stimulated (by 57%; P &lt; 0.05; n = 6) vasopressin release but had no effect on somatodendritic oxytocin release.	Potassium	59-68	arginine vasopressin	Rattus norvegicus	109-120
18793350-5	2008	Amyloid-beta oligomers can interfere with many aspects of neuronal membrane functions and can evoke potassium (K+) efflux from neurons.	Potassium	100-109	amyloid beta precursor protein	Homo sapiens	0-12
18955660-4	2008	Using a transgenic mouse model, we found that intron 1 deletion resulted in the overexpression of L- and KS-WNK1 in the distal convoluted tubule and ubiquitous ectopic KS-WNK1 expression.	Potassium	105-107	WNK lysine deficient protein kinase 1	Mus musculus	108-112
18682608-3	2008	Diabetes in TgRIP-SREBP-2 mice was primarily due to defects in glucose- and potassium-stimulated insulin secretion as determined by glucose tolerance test.	Potassium	76-85	sterol regulatory element binding factor 2	Mus musculus	18-25
18852288-5	2008	In fact, potassium-induced dimerization of the G domain leads to stimulation of the GTPase activity in MnmE but not in GTPBP3.	Potassium	9-18	GTP binding protein 3, mitochondrial	Homo sapiens	119-125
18852288-6	2008	The GTPBP3 N-terminal domain mediates a potassium-independent dimerization, which appears as an evolutionarily conserved property of the protein family, probably related to the construction of the binding site for the one-carbon-unit donor in the modification reaction.	Potassium	40-49	GTP binding protein 3, mitochondrial	Homo sapiens	4-10
19106374-6	2008	Permeability ratio determination and competition experiments reveled a weak preference of CASTOR for cations such as potassium over anions.	Potassium	117-126	CASTOR	Lotus japonicus	90-96
18988745-1	2008	The effects of potassium ion on the nested allostery of GroEL are due to increases in the affinity for nucleotide.	Potassium	15-24	heat shock protein family D (Hsp60) member 1	Homo sapiens	56-61
19180911-7	2008	CONCLUSION: Vasopressin may down-regulate the expression of AQP7 mRNA in the endolymphatic sac and induce a decreased absorption of endolymph, which decreases the water permeability in the potassium ions recycle pathway in the organ of Corti and disturbs the circulation of endolymph, resulting in endolymphatic hydrops.	Potassium	189-198	arginine vasopressin	Rattus norvegicus	12-23
19180911-7	2008	CONCLUSION: Vasopressin may down-regulate the expression of AQP7 mRNA in the endolymphatic sac and induce a decreased absorption of endolymph, which decreases the water permeability in the potassium ions recycle pathway in the organ of Corti and disturbs the circulation of endolymph, resulting in endolymphatic hydrops.	Potassium	189-198	aquaporin 7	Rattus norvegicus	60-64
19080500-10	2008	CONCLUSION: During HI, the downregulation of outward potassium (K+) conductance may prevent the emission of intracellularly accumulated K+ ions, thus resulting in osmotically derived water influx into astrocytes via aquaporin-4 and then cell swelling.	Potassium	53-62	aquaporin 4	Rattus norvegicus	216-227
18937460-1	2008	The potassium graphite reduction of L:PCl3 leads to the formation of carbene-stabilized diphosphorus molecules, L:P-P:L, 1 (L: = :C{N(2,6-Pri2C6H3)CH}2) and 2 (L: = :C{N(2,4,6-Me3C6H2)CH}2), respectively.	Potassium	4-13	PHD finger protein 19	Homo sapiens	38-42
18812827-7	2008	Intrinsic sensitivity to CO2/pH of orexin neurons may impact on brainstem chemosensitive neurons, and this effect likely involves TWIK (tandem of P domains in a weak inwardly rectifying K+ channel)-related acid sensitive K+ (TASK)-like potassium currents.	Potassium	236-245	hypocretin neuropeptide precursor	Homo sapiens	35-41
18757477-6	2008	Cx43+/- myocytes had significantly shorter action potential durations (APD) and increased steady-state (Iss) and inward rectifier (I(K1)) potassium currents compared with those of wild-type littermate cells.	Potassium	138-147	gap junction protein, alpha 1	Mus musculus	0-4
18757482-1	2008	Stable coexpression of human (h)KCNQ1 and hKCNE1 in human embryonic kidney (HEK)-293 cells reconstitutes a nativelike slowly activating delayed rectifier K+ current (HEK-I(Ks)), allowing beta-adrenergic modulation of the current by stimulation of endogenous receptors in the host cell line.	Potassium	172-174	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	32-37
18757482-1	2008	Stable coexpression of human (h)KCNQ1 and hKCNE1 in human embryonic kidney (HEK)-293 cells reconstitutes a nativelike slowly activating delayed rectifier K+ current (HEK-I(Ks)), allowing beta-adrenergic modulation of the current by stimulation of endogenous receptors in the host cell line.	Potassium	172-174	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	42-48
18694623-0	2008	Activation of interleukin-1beta receptor suppresses the voltage-gated potassium currents in the small-diameter trigeminal ganglion neurons following peripheral inflammation.	Potassium	70-79	interleukin 1 beta	Rattus norvegicus	14-31
19046382-8	2008	PKRi does, however, inhibit the activity of certain cyclin-dependent kinases (CDKs), including CDK1, CDK2 and CDK5 both in vitro and in low potassium-treated neurons.	Potassium	140-149	cyclin-dependent kinase 1	Mus musculus	78-82
19106513-5	2008	Eleven days following the administration of docetaxel: 30 mg/m2 and nedaplatin: 30 mg/m2, the patient developed TLS (serum creatinine: 8.57 mg/dL, uric acid: 11.0 mg/dL, serum potassium: 6.3 mEq/L, serum phosphorus: 7.18 mg/dL).	Potassium	176-185	FUS RNA binding protein	Homo sapiens	112-115
18672046-1	2008	A decrease in the expression of inwardly rectifying potassium (Kir) currents is a characteristic feature of retinal glial (Muller) cells in various retinopathies, e.g., after transient retinal ischemia.	Potassium	52-61	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	63-66
18790060-0	2008	Neuropeptide Y activates a G-protein-coupled inwardly rectifying potassium current and dampens excitability in the lateral amygdala.	Potassium	65-74	neuropeptide Y	Rattus norvegicus	0-14
19069684-2	2008	Massive shift of potassium into cells is caused by elevated levels of insulin and catecholamines in the blood.	Potassium	17-26	insulin	Homo sapiens	70-77
18755687-7	2008	Furthermore, islets isolated from MEc-null MOD1(-/-) mice exhibit normal glucose- and potassium-stimulated insulin secretion.	Potassium	86-95	chemokine (C-C motif) ligand 28	Mus musculus	34-37
18958364-7	2008	In addition, the potassium- and capsaicin-stimulated release of CGRP from the culture of sensory neurons isolated from Nf1+/- mice was more than double that from the culture of wildtype neurons.	Potassium	17-26	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	64-68
18786520-4	2008	Since IGF2 has been shown to stimulate endogenous ACh release, we measured the release of ACh from hippocampal and frontal cortical slices from rats on postnatal day (P) 18, P24, P34 and P80 in response to a depolarizing concentration of potassium (45 mM or 25 mM) or to IGF2 treatment in the absence or presence of a depolarizing concentration of potassium (25 mM).	Potassium	238-247	insulin-like growth factor 2	Rattus norvegicus	6-10
18786520-4	2008	Since IGF2 has been shown to stimulate endogenous ACh release, we measured the release of ACh from hippocampal and frontal cortical slices from rats on postnatal day (P) 18, P24, P34 and P80 in response to a depolarizing concentration of potassium (45 mM or 25 mM) or to IGF2 treatment in the absence or presence of a depolarizing concentration of potassium (25 mM).	Potassium	238-247	TATA-box binding protein associated factor 6	Rattus norvegicus	187-190
18786520-4	2008	Since IGF2 has been shown to stimulate endogenous ACh release, we measured the release of ACh from hippocampal and frontal cortical slices from rats on postnatal day (P) 18, P24, P34 and P80 in response to a depolarizing concentration of potassium (45 mM or 25 mM) or to IGF2 treatment in the absence or presence of a depolarizing concentration of potassium (25 mM).	Potassium	348-357	insulin-like growth factor 2	Rattus norvegicus	6-10
18786520-4	2008	Since IGF2 has been shown to stimulate endogenous ACh release, we measured the release of ACh from hippocampal and frontal cortical slices from rats on postnatal day (P) 18, P24, P34 and P80 in response to a depolarizing concentration of potassium (45 mM or 25 mM) or to IGF2 treatment in the absence or presence of a depolarizing concentration of potassium (25 mM).	Potassium	348-357	TATA-box binding protein associated factor 6	Rattus norvegicus	187-190
18958364-7	2008	In addition, the potassium- and capsaicin-stimulated release of CGRP from the culture of sensory neurons isolated from Nf1+/- mice was more than double that from the culture of wildtype neurons.	Potassium	17-26	neurofibromin 1	Mus musculus	119-122
18669623-0	2008	Ether-a-go-go-related gene 3 is the main candidate for the E-4031-sensitive potassium current in the pacemaker interstitial cells of Cajal.	Potassium	76-85	ETS transcription factor	Mus musculus	0-26
18713648-0	2008	Chronic lentiviral expression of inwardly rectifying K+ channels (Kir2.1) reduces neuronal activity and downregulates voltage-gated potassium currents in hippocampus.	Potassium	132-141	potassium inwardly-rectifying channel, subfamily J, member 2	Rattus norvegicus	66-72
18837770-3	2008	Initial treatment with insulin drip resulted in a decrease in serum potassium to 5.3 mmol/L, but no significant change in mental status or other laboratory parameters.	Potassium	68-77	insulin	Homo sapiens	23-30
18547676-5	2008	Sequential labeling experiments indicate that there is basal surface insertion of GluR1, GluR2 and GluR3, and that this insertion is strongly increased following potassium depolarization.	Potassium	162-171	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	82-87
18547676-5	2008	Sequential labeling experiments indicate that there is basal surface insertion of GluR1, GluR2 and GluR3, and that this insertion is strongly increased following potassium depolarization.	Potassium	162-171	glutamate ionotropic receptor AMPA type subunit 3	Homo sapiens	99-104
18684900-1	2008	Whereas Kvbeta2 subunits modulate potassium current properties carried by Kv1 channel complexes in heterologous systems, little is known about the contributions of Kvbeta2 subunits to native potassium channel function.	Potassium	34-43	potassium channel, voltage gated subfamily A regulatory beta subunit 2 L homeolog	Xenopus laevis	8-15
18845707-7	2008	RESULTS: Relative to non-consumers, bean consumers had higher intakes of dietary fiber, potassium, magnesium, iron, and copper (p"s &lt; 0.05).	Potassium	88-97	brain expressed associated with NEDD4 1	Homo sapiens	36-40
18620059-4	2008	We report that 17beta-estradiol clearly activates ERK phosphorylation in CGC cultured in low potassium via ERalpha localized in the plasma membrane and without the activation of the insulin-like growth factor-I receptor.	Potassium	93-102	mitogen-activated protein kinase 1	Homo sapiens	50-53
18620059-4	2008	We report that 17beta-estradiol clearly activates ERK phosphorylation in CGC cultured in low potassium via ERalpha localized in the plasma membrane and without the activation of the insulin-like growth factor-I receptor.	Potassium	93-102	estrogen receptor 1	Homo sapiens	107-114
25983985-0	2008	The relationship between effluent potassium due to cellular release, free water transport and CA125 in peritoneal dialysis patients.	Potassium	34-43	mucin 16, cell surface associated	Homo sapiens	94-99
18633341-6	2008	Only IL-6 levels and age were found to be independent correlates in these growth hormone-induced variations in plasma potassium and blood amino acids.	Potassium	118-127	interleukin 6	Homo sapiens	5-9
18633341-6	2008	Only IL-6 levels and age were found to be independent correlates in these growth hormone-induced variations in plasma potassium and blood amino acids.	Potassium	118-127	growth hormone 1	Homo sapiens	74-88
18675331-0	2008	Effects of 3-benzidino-6-phenylpyridazine, as an acetylcholinesterase inhibitor, on outward potassium current in acutely isolated rat hippocampal pyramidal neurons.	Potassium	92-101	acetylcholinesterase	Rattus norvegicus	49-69
18468748-12	2008	ACE-inhibitor plus ARB therapy did not change GFR, whereas it increased serum potassium levels (by 0.10 mEq/L versus ACE-inhibitor and 0.19 mEq/L versus ARB therapy) and decreased blood pressure.	Potassium	78-87	angiotensin I converting enzyme	Homo sapiens	0-3
18468748-14	2008	CONCLUSIONS: The antiproteinuric response to ACE-inhibitor plus ARB therapy versus either monotherapy is consistently greater and strictly related to baseline proteinuria, associated with only moderate increase in serum potassium levels, and not peculiar to immunoglobulin A nephropathy.	Potassium	220-229	angiotensin I converting enzyme	Homo sapiens	45-48
18565539-1	2008	The Ca(2+)-independent transient outward potassium current (I(to)) encoded by the Kv4 family of potassium channels, is central to normal repolarization of cardiac myocytes.	Potassium	41-50	potassium voltage-gated channel subfamily A member 4	Rattus norvegicus	82-85
18695394-3	2008	Mutations of WNK1 and WNK4 in humans cause hypertension and hyperkalemia at least partly by altering renal sodium and potassium transport.	Potassium	118-127	WNK lysine deficient protein kinase 1	Homo sapiens	13-17
18695394-3	2008	Mutations of WNK1 and WNK4 in humans cause hypertension and hyperkalemia at least partly by altering renal sodium and potassium transport.	Potassium	118-127	WNK lysine deficient protein kinase 4	Homo sapiens	22-26
18715799-3	2008	This is illustrated by the discovery that Nalp3 and Nalp1 are specifically activated by low concentrations of intracellular potassium.	Potassium	124-133	NLR family pyrin domain containing 3	Homo sapiens	42-47
18715799-3	2008	This is illustrated by the discovery that Nalp3 and Nalp1 are specifically activated by low concentrations of intracellular potassium.	Potassium	124-133	NLR family pyrin domain containing 1	Homo sapiens	52-57
18214462-0	2008	Effects of changes in extracellular pH and potassium concentration on Kv1.3 inactivation.	Potassium	43-52	potassium voltage-gated channel subfamily A member 3	Homo sapiens	70-75
18214462-3	2008	Here we examined the effects of extracellular potassium [K+]e and pHe on the rate of inactivation of Kv1.3 using whole-cell patch-clamp.	Potassium	46-55	potassium voltage-gated channel subfamily A member 3	Homo sapiens	101-106
18577565-9	2008	Together, these data support an inhibitory action of Uts2d on renal tubule sodium and potassium reabsorption in the rat, in addition to its previously described renal haemodynamic effects.	Potassium	86-95	urotensin 2B	Rattus norvegicus	53-58
18599533-11	2008	Other substitutions of S140 or V141 in KCNQ1 caused variable shifts in the voltage dependence of activation, but slowed I(Ks) deactivation to a much lesser extent than the AF-associated mutations.	Potassium	122-124	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	39-44
18599533-14	2008	Together our findings suggest that altered charge-pair interactions within the voltage sensor module of KCNQ1 subunits may account for slowed I(Ks) deactivation induced by S140 or V141.	Potassium	144-146	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	104-109
18780802-8	2008	Further analyses of the nrt1.5 mutants revealed a regulatory loop between nitrate and potassium at the xylem transport step.	Potassium	86-95	nitrate transporter 1.1	Arabidopsis thaliana	24-28
18636750-2	2008	Importantly, the physical interaction of Kv2.1 with syntaxin was shown to be involved in the facilitation of secretion from PC12 cells, which was independent of potassium currents.	Potassium	161-170	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	41-46
19055123-4	2008	A urine sample shows inappropriate potassium elimination associated with both low plasmatic renin and aldosterone levels, orienting the diagnosis toward a case of pseudohyperaldosteronism.	Potassium	35-44	renin	Homo sapiens	92-97
18702730-5	2008	Consistent with the role of GLUT4 in insulin-responsive tissues, the glucose transporter was thought to be responsible for facilitating glucose uptake into these pyramidal neurones in response to potassium-induced depolarisation or cAMP activation as the glucose influx was sensitive to indinavir treatment.	Potassium	196-205	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	28-33
18441034-5	2008	We tested the hypothesis that potassium lateral diffusion coupling is responsible for the coupling mechanisms for network periodicity in a nonsynaptic model of epilepsy in vivo using a CA1 pyramidal neuron network model The simulation results show that 1), potassium lateral diffusion coupling is crucial for establishing epileptiform activity similar to that generated experimentally; and 2), there exists a scaling relation between the critical coupling strength and the number of cells in the network.	Potassium	30-39	carbonic anhydrase 1	Rattus norvegicus	185-188
18183482-2	2008	We have recently demonstrated that pretreatment with LINGO-1 antagonist (LINGO-1-Fc) inhibited low potassium-induced cerebellar granular neurons (CGNs) apoptosis.	Potassium	99-108	leucine rich repeat and Ig domain containing 1	Homo sapiens	53-60
18183482-2	2008	We have recently demonstrated that pretreatment with LINGO-1 antagonist (LINGO-1-Fc) inhibited low potassium-induced cerebellar granular neurons (CGNs) apoptosis.	Potassium	99-108	leucine rich repeat and Ig domain containing 1	Homo sapiens	73-80
18183482-6	2008	Several apoptosis-associated signaling factors, GSK-3beta, ERK1/2, and Rho GTPases, were observed to be activated in response to potassium deprivation and the activation/dephosphorylation of GSK-3beta was suppressed by LINGO-1-Fc pretreatment compared with control group.	Potassium	129-138	glycogen synthase kinase 3 beta	Homo sapiens	48-57
18183482-6	2008	Several apoptosis-associated signaling factors, GSK-3beta, ERK1/2, and Rho GTPases, were observed to be activated in response to potassium deprivation and the activation/dephosphorylation of GSK-3beta was suppressed by LINGO-1-Fc pretreatment compared with control group.	Potassium	129-138	mitogen-activated protein kinase 3	Homo sapiens	59-65
18183482-6	2008	Several apoptosis-associated signaling factors, GSK-3beta, ERK1/2, and Rho GTPases, were observed to be activated in response to potassium deprivation and the activation/dephosphorylation of GSK-3beta was suppressed by LINGO-1-Fc pretreatment compared with control group.	Potassium	129-138	glycogen synthase kinase 3 beta	Homo sapiens	191-200
18183482-6	2008	Several apoptosis-associated signaling factors, GSK-3beta, ERK1/2, and Rho GTPases, were observed to be activated in response to potassium deprivation and the activation/dephosphorylation of GSK-3beta was suppressed by LINGO-1-Fc pretreatment compared with control group.	Potassium	129-138	leucine rich repeat and Ig domain containing 1	Homo sapiens	219-226
18183482-7	2008	Besides, the endogenous LINGO-1 expression level of CGN cultures was augmented by low potassium stimuli and restrained by LINGO-1 antagonist treatment.	Potassium	86-95	leucine rich repeat and Ig domain containing 1	Homo sapiens	24-31
18183482-7	2008	Besides, the endogenous LINGO-1 expression level of CGN cultures was augmented by low potassium stimuli and restrained by LINGO-1 antagonist treatment.	Potassium	86-95	cingulin	Homo sapiens	52-55
19358754-14	2008	Level of urinary TMT-cl of exposed group was negatively correlated with blood potassium (r = -0.4456, P &lt; 0.01).	Potassium	78-87	tryptase gamma 1	Homo sapiens	17-20
19124424-12	2008	Independent of the medical indication for its use, the concept of dual RAS-blockade with an ARB-ACE-I-combination should clinically be used with caution and a close monitoring of potassium levels and kidney function.	Potassium	179-188	angiotensin I converting enzyme	Homo sapiens	96-99
19358754-16	2008	Blood potassium is an early biomarker of effect for TMT-cl poisoning so as to find poisoning population early.	Potassium	6-15	tryptase gamma 1	Homo sapiens	52-55
18635795-6	2008	Genetic and molecular analyses revealed that quiver, a mutation that impairs Shaker-dependent potassium current, is an allele of sleepless.	Potassium	94-103	quiver	Drosophila melanogaster	129-138
18474599-7	2008	In accordance with this proposed mechanism, low pH modified K2P2.1 selectivity toward potassium.	Potassium	86-95	potassium two pore domain channel subfamily K member 2	Homo sapiens	60-66
18625963-7	2008	The KCNQ2 p.Ile592Met variant displayed a significant reduction of potassium current amplitude in Xenopus oocytes and was present only once in 552 controls.	Potassium	67-76	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	4-9
18498087-2	2008	We show that forced expression of HDAC4 in cerebellar granule neurons protects them against low potassium-induced apoptosis.	Potassium	96-105	histone deacetylase 4	Mus musculus	34-39
18502415-2	2008	GSK-3 beta inhibitors inhibit apoptosis mediated by serum and potassium withdrawal (S/K withdrawal) and GSK-3 beta activation, as measured by beta-catenin degradation.	Potassium	62-71	glycogen synthase kinase 3 beta	Homo sapiens	0-10
18419759-7	2008	Accordingly, using in vitro superfusion system of lumbar dorsal root ganglion and spinal cord explants of healthy rats, we show that potassium or capsaicin evoke calcium-dependent release of CCL2.	Potassium	133-142	C-C motif chemokine ligand 2	Rattus norvegicus	191-195
19343122-0	2008	Effects of intermittent and long-term glucose-insulin-potassium infusion in patients with systolic heart failure.	Potassium	54-63	insulin	Homo sapiens	46-53
18577586-7	2008	Activation of the Nalp3 inflammasome by silica required both an efflux of intracellular potassium and the generation of reactive oxygen species.	Potassium	88-97	NLR family pyrin domain containing 3	Homo sapiens	18-23
18673254-7	2008	The parallel study on the complexation ability of the potassium complex of Monensin A (MonK, 1b) towards Co(II) and Mn(II) showed the formation of the isostructural complexes 2a and 2b accompanied by loss of the potassium ion due to the new coordination mode of the ligand.	Potassium	54-63	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	105-111
18387944-6	2008	Both structures display a novel type II potassium-binding site located on the PDHK2 interface with the L2 domain.	Potassium	40-49	pyruvate dehydrogenase kinase 2	Homo sapiens	78-83
18387944-8	2008	Evidence is also presented that potassium ions are indispensable for the cross-talk between the nucleotide- and L2-binding sites of PDHK2.	Potassium	32-41	pyruvate dehydrogenase kinase 2	Homo sapiens	132-137
18447324-2	2008	Cyt c-modified BDND electrode exhibited a pair of quasi-reversible and well-defined redox peaks with a formal potential (E(0)) of 0.061 V (vs Ag/AgCl) in 0.1 M phosphate buffer solution (pH 7.0) and a surface-controlled process with a high electron transfer constant (ks) of 5.2 +/- 0.6 s(-1).	Potassium	93-95	cytochrome c, somatic	Homo sapiens	0-5
24459520-4	2008	PGI2 (and possibly PGE2) increases potassium secretion mainly by stimulating secretion of renin and activating the renin-angiotensin system, which leads to increased secretion of aldosterone.	Potassium	35-44	renin	Homo sapiens	90-95
18536731-1	2008	BACKGROUND AND PURPOSE: The human cardiac transient outward potassium current (Ito) is believed to be composed of the pore-forming Kv4.3 alpha-subunit, coassembled with modulatory beta-subunits as KChIP2, MiRP1 and DPP6 proteins.	Potassium	60-69	potassium voltage-gated channel subfamily D member 3	Homo sapiens	131-136
18536731-1	2008	BACKGROUND AND PURPOSE: The human cardiac transient outward potassium current (Ito) is believed to be composed of the pore-forming Kv4.3 alpha-subunit, coassembled with modulatory beta-subunits as KChIP2, MiRP1 and DPP6 proteins.	Potassium	60-69	potassium voltage-gated channel interacting protein 2	Homo sapiens	197-203
18536731-1	2008	BACKGROUND AND PURPOSE: The human cardiac transient outward potassium current (Ito) is believed to be composed of the pore-forming Kv4.3 alpha-subunit, coassembled with modulatory beta-subunits as KChIP2, MiRP1 and DPP6 proteins.	Potassium	60-69	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	205-210
18536731-1	2008	BACKGROUND AND PURPOSE: The human cardiac transient outward potassium current (Ito) is believed to be composed of the pore-forming Kv4.3 alpha-subunit, coassembled with modulatory beta-subunits as KChIP2, MiRP1 and DPP6 proteins.	Potassium	60-69	dipeptidyl peptidase like 6	Homo sapiens	215-219
24459520-4	2008	PGI2 (and possibly PGE2) increases potassium secretion mainly by stimulating secretion of renin and activating the renin-angiotensin system, which leads to increased secretion of aldosterone.	Potassium	35-44	renin	Homo sapiens	115-120
18197357-4	2008	Potassium-stimulated DA was increased in male and female +/- DAT mice and maximally stimulated DA was obtained from +/- DAT females, although these mice showed the lowest DA concentrations.	Potassium	0-9	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	Mus musculus	61-64
18328558-5	2008	Stimulation with noxious heat, low pH, inflammatory mediators and high potassium concentration increased CGRP release.	Potassium	71-80	calcitonin related polypeptide alpha	Homo sapiens	105-109
18266681-1	2008	INTRODUCTION: Slowly activating delayed-rectifier potassium currents in the heart are produced by a complex protein with alpha and beta subunits composed of the potassium voltage-gated channel KQT-like subfamily, member 1 (KCNQ1) and the potassium voltage-gated channel Isk-related family, member 1 (KCNE1), respectively.	Potassium	50-59	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	161-221
18686609-1	2008	OBJECTIVE: To investigate the effect of unaggregated Abeta(25.35) on delayed rectifier potassium current (I(K)) in neonatal rat hippocampal CA3 pyramidal neurons.	Potassium	87-96	amyloid beta precursor protein	Rattus norvegicus	53-58
18772606-6	2008	The effect of CHP-NY-ESO-1 on the hERG-dependent potassium currents was also examined using in vitro cultured cell system, and no inhibition of hERG currents was observed.	Potassium	49-58	ETS transcription factor ERG	Homo sapiens	34-38
18489774-4	2008	RESULTS: HIV-1 Nef induces alterations in the intracellular potassium concentration in CD4+ T-lymphoblastoid cells, but not intracellular pH.	Potassium	60-69	Nef	Human immunodeficiency virus 1	15-18
18456837-4	2008	BP554 is a 5-HT1A agonist acting primarily on the membrane of efferent neurons by potassium-induced hyperpolarization.	Potassium	82-91	5-hydroxytryptamine receptor 1A	Homo sapiens	11-17
17669648-5	2008	The values of half-saturation constant Ks for acetone, MEK and MIPK were 26.80, 21.56 and 22.96 ppm, respectively.	Potassium	39-41	mitogen-activated protein kinase kinase 7	Homo sapiens	55-58
18441444-2	2008	The syndrome is caused by homozygous or compound heterozygous mutations in genes KCNQ1 and KCNE1, which are responsible for encoding the delayed rectifier repolarizing current, I(Ks).	Potassium	179-181	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	81-86
18441444-2	2008	The syndrome is caused by homozygous or compound heterozygous mutations in genes KCNQ1 and KCNE1, which are responsible for encoding the delayed rectifier repolarizing current, I(Ks).	Potassium	179-181	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	91-96
18266681-1	2008	INTRODUCTION: Slowly activating delayed-rectifier potassium currents in the heart are produced by a complex protein with alpha and beta subunits composed of the potassium voltage-gated channel KQT-like subfamily, member 1 (KCNQ1) and the potassium voltage-gated channel Isk-related family, member 1 (KCNE1), respectively.	Potassium	50-59	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	223-228
18266681-1	2008	INTRODUCTION: Slowly activating delayed-rectifier potassium currents in the heart are produced by a complex protein with alpha and beta subunits composed of the potassium voltage-gated channel KQT-like subfamily, member 1 (KCNQ1) and the potassium voltage-gated channel Isk-related family, member 1 (KCNE1), respectively.	Potassium	50-59	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	238-298
18385479-1	2008	Voltage-gated KCNQ potassium channels are responsible for slowly activating potassium currents in heart, brain, and other tissues.	Potassium	19-28	KCNQ potassium channel	Drosophila melanogaster	14-18
18266681-1	2008	INTRODUCTION: Slowly activating delayed-rectifier potassium currents in the heart are produced by a complex protein with alpha and beta subunits composed of the potassium voltage-gated channel KQT-like subfamily, member 1 (KCNQ1) and the potassium voltage-gated channel Isk-related family, member 1 (KCNE1), respectively.	Potassium	50-59	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	300-305
18234845-0	2008	ACE-inhibitor or AT2-antagonist therapy of renal transplant recipients is associated with an increase in serum potassium concentrations.	Potassium	111-120	angiotensin I converting enzyme	Homo sapiens	0-3
18234845-0	2008	ACE-inhibitor or AT2-antagonist therapy of renal transplant recipients is associated with an increase in serum potassium concentrations.	Potassium	111-120	angiotensin II receptor type 2	Homo sapiens	17-20
18420307-2	2008	Bolus U-II injection (15 nmol kg(-1)) caused a transient decrease in glomerular filtration rate (GFR), urine flow rate (UV), urinary sodium (UNaV) and potassium excretion (U(K)V) that corresponded with a committed decrease in mean arterial pressure (MAP) and renal blood flow (RBF) during the first 30 min.	Potassium	151-160	urotensin 2	Rattus norvegicus	6-10
18385985-0	2008	Effects of Cd2+ on transient outward and delayed rectifier potassium currents in acutely isolated rat hippocampal CA1 neurons.	Potassium	59-68	Cd2 molecule	Rattus norvegicus	11-14
18385985-0	2008	Effects of Cd2+ on transient outward and delayed rectifier potassium currents in acutely isolated rat hippocampal CA1 neurons.	Potassium	59-68	carbonic anhydrase 1	Rattus norvegicus	114-117
18417695-2	2008	In the CNS, potassium ion (K+) buffering is dependent on the glia-specific inward rectifying K+ channel Kir4.1.	Potassium	12-21	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	104-110
18359846-0	2008	The ionic environment controls the contribution of the barley HvHAK1 transporter to potassium acquisition.	Potassium	84-93	hak1	Hordeum vulgare	62-68
18416824-6	2008	RESULTS: P/Q-, N- and L-type channels each mediate a significant fraction of potassium-stimulated release of glutamate and CGRP.	Potassium	77-86	calcitonin-related polypeptide alpha	Rattus norvegicus	123-127
18416824-7	2008	We determined that 5-HT significantly inhibits potassium-stimulated release of both glutamate and CGRP.	Potassium	47-56	calcitonin-related polypeptide alpha	Rattus norvegicus	98-102
18307835-1	2008	BACKGROUND: Renin-angiotensin system (RAS) blockade with ACE inhibitor and/or angiotensin receptor blocker therapy can lead to increased potassium levels, hence the need to assess dual blockade involving a direct renin inhibitor.	Potassium	137-146	renin	Homo sapiens	12-17
18314270-8	2008	In addition, TNF-alpha induced a significant increase in IV ramps at a potential of +20 mV, which did not exist when the experiments were conducted in a potassium-free solution, indicating that this effect is mainly the result of a change in potassium conductance.	Potassium	153-162	tumor necrosis factor	Rattus norvegicus	13-22
18314270-8	2008	In addition, TNF-alpha induced a significant increase in IV ramps at a potential of +20 mV, which did not exist when the experiments were conducted in a potassium-free solution, indicating that this effect is mainly the result of a change in potassium conductance.	Potassium	242-251	tumor necrosis factor	Rattus norvegicus	13-22
18471074-9	2008	Although the Cav2 channel subtypes differ in their voltage dependence of inactivation, by adjusting pre-trigger potassium concentrations, the degree of steady-state inactivation can be more closely matched across Cav2 subtypes to assess molecular selectivity.	Potassium	112-121	caveolin 2	Homo sapiens	13-17
18307835-1	2008	BACKGROUND: Renin-angiotensin system (RAS) blockade with ACE inhibitor and/or angiotensin receptor blocker therapy can lead to increased potassium levels, hence the need to assess dual blockade involving a direct renin inhibitor.	Potassium	137-146	angiotensin I converting enzyme	Homo sapiens	57-60
18307835-1	2008	BACKGROUND: Renin-angiotensin system (RAS) blockade with ACE inhibitor and/or angiotensin receptor blocker therapy can lead to increased potassium levels, hence the need to assess dual blockade involving a direct renin inhibitor.	Potassium	137-146	renin	Homo sapiens	213-218
18413801-4	2008	Two well-known G-quadruplex-interactive agents, TMPyP4 and Se2SAP, stabilize G-quadruplex structures formed by this sequence in the presence of a potassium ion, although Se2SAP is at least 10-fold more effective in binding to the G-quadruplex than TMPyP4.	Potassium	146-155	fucosyltransferase 2	Homo sapiens	59-62
18572597-1	2008	Direct reaction of herringbone, platelet, or narrow, tubular herringbone graphitic carbon nanofibers (GCNFs) with molten potassium gives K/GCNF intercalates with stoichiometric control of potassium loading.	Potassium	121-130	nuclear receptor subfamily 6 group A member 1	Homo sapiens	102-106
18572597-1	2008	Direct reaction of herringbone, platelet, or narrow, tubular herringbone graphitic carbon nanofibers (GCNFs) with molten potassium gives K/GCNF intercalates with stoichiometric control of potassium loading.	Potassium	188-197	nuclear receptor subfamily 6 group A member 1	Homo sapiens	102-106
18447646-7	2008	DOX-induced expression of the Kir2.1 channels in mES and hES cells led to robust expression of the inwardly rectifying potassium (K(+)) current and thereby hyperpolarized the resting membrane potential (RMP).	Potassium	119-128	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	30-36
18447646-7	2008	DOX-induced expression of the Kir2.1 channels in mES and hES cells led to robust expression of the inwardly rectifying potassium (K(+)) current and thereby hyperpolarized the resting membrane potential (RMP).	Potassium	119-128	ribosome binding protein 1	Homo sapiens	57-60
18211905-6	2008	Potassium restriction had no effect on the expression of RPTPalpha, but it increased the association between c-Src and RPTPalpha in the renal cortex and outer medulla.	Potassium	0-9	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	109-114
18211905-6	2008	Potassium restriction had no effect on the expression of RPTPalpha, but it increased the association between c-Src and RPTPalpha in the renal cortex and outer medulla.	Potassium	0-9	protein tyrosine phosphatase receptor type A	Homo sapiens	119-128
17968975-0	2008	Insulin effect on serum potassium and auto-inhibition of insulin secretion is intact in a patient with leprechaunism despite severe impairment of substrates metabolism.	Potassium	24-33	insulin	Homo sapiens	0-7
18184758-3	2008	We have tested whether common genetic variation in the gene encoding the beta-subunit of the epithelial sodium channel (SCNN1B) affects plasma potassium and blood pressure level in a study of 1,425 members of 248 families ascertained on a proband with hypertension.	Potassium	143-152	sodium channel epithelial 1 subunit beta	Homo sapiens	120-126
18184758-9	2008	We have shown a modest sized but highly significant effect of common genetic variation in the SCNN1B gene on plasma potassium.	Potassium	116-125	sodium channel epithelial 1 subunit beta	Homo sapiens	94-100
18536530-3	2008	We examined the expression of DNMT1 and DNMT3a, representative of a maintenance and de novo methyltransferase respectively, in response to in-vitro depolarization of cortical neurons, using standard techniques such as high potassium (KCl) or the sodium channel agonist veratridine.	Potassium	223-232	DNA methyltransferase 1	Homo sapiens	30-35
18277144-7	2008	The expression of WNK1 is upregulated by potassium deficiency, raising the possibility that WNK1 may contribute to salt-sensitive essential hypertension associated with potassium deficiency.	Potassium	41-50	WNK lysine deficient protein kinase 1	Homo sapiens	18-22
18277144-7	2008	The expression of WNK1 is upregulated by potassium deficiency, raising the possibility that WNK1 may contribute to salt-sensitive essential hypertension associated with potassium deficiency.	Potassium	41-50	WNK lysine deficient protein kinase 1	Homo sapiens	92-96
18277144-7	2008	The expression of WNK1 is upregulated by potassium deficiency, raising the possibility that WNK1 may contribute to salt-sensitive essential hypertension associated with potassium deficiency.	Potassium	169-178	WNK lysine deficient protein kinase 1	Homo sapiens	18-22
18277144-7	2008	The expression of WNK1 is upregulated by potassium deficiency, raising the possibility that WNK1 may contribute to salt-sensitive essential hypertension associated with potassium deficiency.	Potassium	169-178	WNK lysine deficient protein kinase 1	Homo sapiens	92-96
18279388-2	2008	Heterologous expression studies have demonstrated diverse functional effects of KCNE subunits on several K(V) channels, including KCNQ1 (K(V)7.1) that, together with KCNE1, generates the slow-delayed rectifier current (I(Ks)) important for cardiac repolarization.	Potassium	221-223	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	130-135
18364020-0	2008	Kv4 (A-type) potassium currents in the mouse medial nucleus of the trapezoid body.	Potassium	13-22	potassium voltage gated channel, Shaw-related subfamily, member 1	Mus musculus	0-3
18186079-8	2008	Aqp4, Cx43, and Kir4.1/Kir5.1 are co-localized to astrocytic end-feet at the brain vasculature, where they regulate potassium and water transport.	Potassium	116-125	aquaporin 4	Mus musculus	0-4
18186079-8	2008	Aqp4, Cx43, and Kir4.1/Kir5.1 are co-localized to astrocytic end-feet at the brain vasculature, where they regulate potassium and water transport.	Potassium	116-125	gap junction protein, alpha 1	Mus musculus	6-10
18186079-8	2008	Aqp4, Cx43, and Kir4.1/Kir5.1 are co-localized to astrocytic end-feet at the brain vasculature, where they regulate potassium and water transport.	Potassium	116-125	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	16-22
18186079-8	2008	Aqp4, Cx43, and Kir4.1/Kir5.1 are co-localized to astrocytic end-feet at the brain vasculature, where they regulate potassium and water transport.	Potassium	116-125	potassium inwardly-rectifying channel, subfamily J, member 16	Mus musculus	23-29
18279388-2	2008	Heterologous expression studies have demonstrated diverse functional effects of KCNE subunits on several K(V) channels, including KCNQ1 (K(V)7.1) that, together with KCNE1, generates the slow-delayed rectifier current (I(Ks)) important for cardiac repolarization.	Potassium	221-223	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	166-171
18222468-7	2008	By contrast, KCNQ1-I274V causes a gain-of-function in I(Ks) characterized by increased current density, faster activation, and slower deactivation leading to accumulation of instantaneous current upon repeated stimulation.	Potassium	56-58	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	13-18
18302698-12	2008	Endothelin-1 (10 nM) increased the inward rectifier potassium current, hyperpolarization-induced pacemaker current, and the sustained outward potassium current in PV cardiomyocytes with and without pacemaker activity.	Potassium	52-61	endothelin-1	Oryctolagus cuniculus	0-12
18304838-2	2008	In the present work we sought to develop a simplified protocol for measuring the acute activity of MR antagonists on urinary excretion of sodium and potassium in rats based on the original studies of mineralocorticoids in adrenalectomized rats reported by Kagawa et al.	Potassium	149-158	nuclear receptor subfamily 3, group C, member 2	Rattus norvegicus	99-101
18221922-0	2008	Detection and quantification of ppb level potassium in biological samples in the presence of high sodium by ion chromatographic method.	Potassium	42-51	histatin 1	Homo sapiens	32-35
18304838-7	2008	RESULTS: Aldosterone had no significant effect on sodium or potassium excretion and MR antagonists dose-dependently increased the ratio of sodium to potassium.	Potassium	149-158	nuclear receptor subfamily 3, group C, member 2	Rattus norvegicus	84-86
18042732-11	2008	During a voltage-clamp protocol using a prerecorded cardiac action potential, 3 muM PD-307243 increased the total potassium ions passed through hERG channels by 8.8 +/- 1.0-fold (n = 5).	Potassium	114-123	latexin	Homo sapiens	80-83
18042732-11	2008	During a voltage-clamp protocol using a prerecorded cardiac action potential, 3 muM PD-307243 increased the total potassium ions passed through hERG channels by 8.8 +/- 1.0-fold (n = 5).	Potassium	114-123	ETS transcription factor ERG	Homo sapiens	144-148
18166528-0	2008	SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.	Potassium	51-60	solute carrier family 24 member 5	Homo sapiens	0-7
18272489-1	2008	Noninactivating potassium current formed by KCNQ2 (Kv7.2) and KCNQ3 (Kv7.3) subunits resembles neuronal M-currents which are activated by voltage and play a critical role in controlling membrane excitability.	Potassium	16-25	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	44-49
18272489-1	2008	Noninactivating potassium current formed by KCNQ2 (Kv7.2) and KCNQ3 (Kv7.3) subunits resembles neuronal M-currents which are activated by voltage and play a critical role in controlling membrane excitability.	Potassium	16-25	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	51-56
18272489-1	2008	Noninactivating potassium current formed by KCNQ2 (Kv7.2) and KCNQ3 (Kv7.3) subunits resembles neuronal M-currents which are activated by voltage and play a critical role in controlling membrane excitability.	Potassium	16-25	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	62-67
18272489-1	2008	Noninactivating potassium current formed by KCNQ2 (Kv7.2) and KCNQ3 (Kv7.3) subunits resembles neuronal M-currents which are activated by voltage and play a critical role in controlling membrane excitability.	Potassium	16-25	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	69-74
18178318-0	2008	Activating transcription factor 3 up-regulated by c-Jun NH(2)-terminal kinase/c-Jun contributes to apoptosis induced by potassium deprivation in cerebellar granule neurons.	Potassium	120-129	activating transcription factor 3	Rattus norvegicus	0-33
18178318-0	2008	Activating transcription factor 3 up-regulated by c-Jun NH(2)-terminal kinase/c-Jun contributes to apoptosis induced by potassium deprivation in cerebellar granule neurons.	Potassium	120-129	mitogen-activated protein kinase 8	Rattus norvegicus	50-77
18178318-4	2008	Here, we showed that ATF3 was up-regulated under potassium deprivation in CGNs, and this induction was preceded by a rapid and sustained activation of c-Jun NH(2)-terminal kinase/c-Jun signaling pathway, which plays a fundamental role in neuronal apoptosis.	Potassium	49-58	activating transcription factor 3	Rattus norvegicus	21-25
18178318-4	2008	Here, we showed that ATF3 was up-regulated under potassium deprivation in CGNs, and this induction was preceded by a rapid and sustained activation of c-Jun NH(2)-terminal kinase/c-Jun signaling pathway, which plays a fundamental role in neuronal apoptosis.	Potassium	49-58	mitogen-activated protein kinase 8	Rattus norvegicus	151-178
18178318-6	2008	Finally, knockdown of ATF3 by RNA interference protected CGNs from potassium deprivation-induced apoptosis.	Potassium	67-76	activating transcription factor 3	Rattus norvegicus	22-26
18178318-7	2008	Taken together, our results indicate that ATF3 is a downstream target of JNK/c-Jun pathway and contributes to apoptosis induced by potassium deprivation in rat CGNs.	Potassium	131-140	activating transcription factor 3	Rattus norvegicus	42-46
18178318-7	2008	Taken together, our results indicate that ATF3 is a downstream target of JNK/c-Jun pathway and contributes to apoptosis induced by potassium deprivation in rat CGNs.	Potassium	131-140	mitogen-activated protein kinase 8	Rattus norvegicus	73-76
18178321-0	2008	Mechanisms of potassium- and capsaicin-induced axonal calcitonin gene-related peptide release: involvement of L- and T-type calcium channels and TRPV1 but not sodium channels.	Potassium	14-23	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	145-150
18178321-10	2008	These results suggest that slow depolarization by high extracellular potassium activates axonal low threshold (T-type) as well as high threshold-activated (L-type) voltage-gated calcium channels to mediate iCGRP release, and that capsaicin-induced release is largely dependent on calcium influx through TRPV1.	Potassium	69-78	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	303-308
18037918-0	2008	Chlorthalidone inhibits the KvLQT1 potassium current in guinea-pig ventricular myocytes and oocytes from Xenopus laevis.	Potassium	35-44	potassium voltage-gated channel subfamily KQT member 1	Cavia porcellus	28-34
18203179-6	2008	Mutations within the voltage-gated sodium channel alpha-subunit gene (SCN4A) have been described in association with several phenotypes including paramyotonia congenita, hyperkalemic or hypokalemic periodic paralysis, and potassium-aggravated myotonias.	Potassium	222-231	sodium voltage-gated channel alpha subunit 4	Homo sapiens	70-75
18071753-5	2008	TGF-beta alone does not affect low-potassium-induced DNA fragmentation but potentiates low-potassium-induced PM damage.	Potassium	91-100	transforming growth factor beta 1	Homo sapiens	0-8
18071753-2	2008	We have previously shown that cerebellar granule neurons (CGN) degenerate in low potassium via ERK1/2 (extra-cellular-regulated kinase)-dependent plasma membrane (PM) damage and caspase-3-dependent DNA fragmentation.	Potassium	81-90	mitogen-activated protein kinase 3	Homo sapiens	95-101
32688753-10	2008	This supported a model in which AtMHX-mediated proton efflux from vacuoles affects the PMF, potassium influx, and cell expansion.	Potassium	92-101	magnesium/proton exchanger	Arabidopsis thaliana	32-37
18071753-4	2008	GDNF alone prevents low-potassium-induced caspase-3 activation and DNA fragmentation but does not affect either low-potassium-induced ERK activation or PM damage.	Potassium	24-33	glial cell derived neurotrophic factor	Homo sapiens	0-4
18030493-9	2008	The results showed that the G296S mutant exerts a strong dominant-negative effect on potassium currents by reducing the wild type KCNQ4 channel expression at the cell surface.	Potassium	85-94	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	130-135
17947299-0	2008	Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress.	Potassium	7-16	wolframin ER transmembrane glycoprotein	Homo sapiens	60-69
17986649-7	2008	Effects on hK(v)11.1, hK(v)4.3, and hK(v)7.1/hKCNE1 potassium currents and calcium current were not involved.	Potassium	52-61	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	45-51
18221556-7	2008	Ka/Ks analysis and likelihood ratio tests showed considerably higher Ka values and Ka/Ks ratios in numit rps13 than in nucp rps13, indicating increased amino acid sequence divergence in numit rps13.	Potassium	3-5	ribosomal protein S13	Malus domestica	105-110
18221556-7	2008	Ka/Ks analysis and likelihood ratio tests showed considerably higher Ka values and Ka/Ks ratios in numit rps13 than in nucp rps13, indicating increased amino acid sequence divergence in numit rps13.	Potassium	86-88	ribosomal protein S13	Malus domestica	105-110
18006587-7	2008	Our results provide evidence that beta-AR-regulated I Ks channels can play a role in AF and imply that specific I Ks deregulation, perhaps through disruption of the I Ks macromolecular complex necessary for beta-AR-mediated I Ks channel regulation, may be a novel therapeutic strategy for treating this most common arrhythmia.	Potassium	54-56	adrenergic receptor, beta 1	Mus musculus	34-41
18006587-7	2008	Our results provide evidence that beta-AR-regulated I Ks channels can play a role in AF and imply that specific I Ks deregulation, perhaps through disruption of the I Ks macromolecular complex necessary for beta-AR-mediated I Ks channel regulation, may be a novel therapeutic strategy for treating this most common arrhythmia.	Potassium	54-56	adrenergic receptor, beta 1	Mus musculus	207-214
18006587-7	2008	Our results provide evidence that beta-AR-regulated I Ks channels can play a role in AF and imply that specific I Ks deregulation, perhaps through disruption of the I Ks macromolecular complex necessary for beta-AR-mediated I Ks channel regulation, may be a novel therapeutic strategy for treating this most common arrhythmia.	Potassium	114-116	adrenergic receptor, beta 1	Mus musculus	34-41
18006587-7	2008	Our results provide evidence that beta-AR-regulated I Ks channels can play a role in AF and imply that specific I Ks deregulation, perhaps through disruption of the I Ks macromolecular complex necessary for beta-AR-mediated I Ks channel regulation, may be a novel therapeutic strategy for treating this most common arrhythmia.	Potassium	114-116	adrenergic receptor, beta 1	Mus musculus	207-214
18273958-1	2008	BACKGROUND: Patients with genetic evidence of long QT syndromes type 1 and 2 (LQT1, associated with impaired outward potassium current I(Ks); and LQT2, associated with impaired outward potassium current I(Kr)) may have normal baseline QT intervals (phenotype/genotype discordance) and elude clinical detection.	Potassium	117-126	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	78-82
18179896-4	2008	This region contains 59 genes, of which 20 were sequenced, disclosing a heterozygous mutation (484C &gt; T, R162W) in KCNJ13, member 13 of subfamily J of the potassium inwardly rectifying channel family in all affected individuals.	Potassium	158-167	potassium inwardly rectifying channel subfamily J member 13	Homo sapiens	118-124
18179896-8	2008	Functionally, unlike wild-type Kir7.1 whose overexpression in CHO-K1 cells line produces highly selective potassium current, overexpression of R162W mutant Kir7.1 produces a nonselective cation current that depolarizes transfected cells and increases their fragility.	Potassium	106-115	potassium inwardly rectifying channel subfamily J member 13	Homo sapiens	156-162
19163508-3	2008	We tested the hypothesis that potassium lateral diffusion coupling is required to generate periodic epileptiform activity in a zero-Ca(2+) CA1 pyramidal neuron network model.	Potassium	30-39	carbonic anhydrase 1	Homo sapiens	139-142
18651412-3	2008	Inhibition of hERG potassium currents by class III antiarrhythmic drugs causes lengthening of cardiac action potential, which produces a beneficial antiarrhythmic effect.	Potassium	19-28	ETS transcription factor ERG	Homo sapiens	14-18
19088444-0	2008	Reduced calmodulin expression accelerates transient outward potassium current inactivation in diabetic rat heart.	Potassium	60-69	calmodulin 1	Rattus norvegicus	8-18
18273958-1	2008	BACKGROUND: Patients with genetic evidence of long QT syndromes type 1 and 2 (LQT1, associated with impaired outward potassium current I(Ks); and LQT2, associated with impaired outward potassium current I(Kr)) may have normal baseline QT intervals (phenotype/genotype discordance) and elude clinical detection.	Potassium	137-139	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	78-82
18293202-5	2008	Similarly, in vessels constricted with a high potassium solution (60 mM), which inhibits vasodilatation via endothelial-derived hyperpolarising factor (EDHF), TNF-alpha incubation also attenuated bradykinin-induced vasodilatation.	Potassium	46-55	tumor necrosis factor	Homo sapiens	159-168
17955184-8	2008	Patch-clamp experiments performed on tobacco mesophyll protoplasts expressing AKT1 alone or in combination with KDC1::GFP showed voltage-activated inward potassium currents with different properties.	Potassium	154-163	K+ transporter 1	Arabidopsis thaliana	78-82
18628579-9	2008	RESULTS: Multivariate analysis identified reduced eGFR, diabetes, male gender, aging, and use of renin-angiotensin system inhibitors as the factors associated with an elevated serum potassium level.	Potassium	182-191	renin	Homo sapiens	97-102
18079560-2	2008	KCNQ1/KCNE1 complexes generate the very slowly activating cardiac I(Ks) current, whereas assembly with KCNE3 produces a constitutively conducting complex involved in K(+) recycling in epithelia.	Potassium	68-70	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	0-5
18079560-2	2008	KCNQ1/KCNE1 complexes generate the very slowly activating cardiac I(Ks) current, whereas assembly with KCNE3 produces a constitutively conducting complex involved in K(+) recycling in epithelia.	Potassium	68-70	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	6-11
18998101-0	2008	Recording hERG potassium currents and assessing the effects of compounds using the whole-cell patch-clamp technique.	Potassium	15-24	ETS transcription factor ERG	Homo sapiens	10-14
20165558-0	2008	Tumor Necrosis Factor-alpha Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons.	Potassium	63-72	tumor necrosis factor	Rattus norvegicus	0-27
20165558-2	2008	In the present study, using whole-cell patch clamp techniques, the regulation of potassium currents by TNF-alpha was examined in acutely dissociated small dorsal root ganglion neurons.	Potassium	81-90	tumor necrosis factor	Rattus norvegicus	103-112
20165558-3	2008	We found that acute application of TNF-alpha inhibited, in a dose-dependent manner, the non-inactivating sustained potassium current without changing the rapidly inactivating transient current or the kinetics of steady-state inactivation.	Potassium	115-124	tumor necrosis factor	Rattus norvegicus	35-44
20165558-4	2008	The effects of TNF-alpha on potassium currents were similar to that of prostaglandin E2 as reported previously and also demonstrated in the current study.	Potassium	28-37	tumor necrosis factor	Rattus norvegicus	15-24
20165558-5	2008	Furthermore, indomethacin, a potent inhibitor for both cyclo-oxygenase (COX) -1 and COX-2, completely blocked the effect of TNF-alpha on potassium currents.	Potassium	137-146	cytochrome c oxidase I, mitochondrial	Rattus norvegicus	55-79
20165558-5	2008	Furthermore, indomethacin, a potent inhibitor for both cyclo-oxygenase (COX) -1 and COX-2, completely blocked the effect of TNF-alpha on potassium currents.	Potassium	137-146	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	84-89
20165558-5	2008	Furthermore, indomethacin, a potent inhibitor for both cyclo-oxygenase (COX) -1 and COX-2, completely blocked the effect of TNF-alpha on potassium currents.	Potassium	137-146	tumor necrosis factor	Rattus norvegicus	124-133
20165558-6	2008	These results suggest that TNF-alpha may sensitize or activate sensory neurons by suppressing the sustained potassium current in nociceptive DRG neurons, possibly via stimulating the synthesis/release of endogenous prostaglandins.	Potassium	108-117	tumor necrosis factor	Rattus norvegicus	27-36
17955184-9	2008	In particular, the addition of Zn2+ to the bath solution induced a clear decrease of the potassium currents in protoplasts transformed with AKT1 alone, whereas a current potentiation (indicative of KDC1 presence) was observed in protoplasts co-transformed with AKT1 + KDC1::GFP.	Potassium	89-98	K+ transporter 1	Arabidopsis thaliana	140-144
17996852-8	2007	In ethanol-treated cells, dopamine release was inhibited following stimulation by forms of release shown to be PKC-dependent (nicotine, sucrose, and potassium).	Potassium	149-158	protein kinase C, gamma	Rattus norvegicus	111-114
18509482-3	2008	This case provides supporting evidence that the mTOR pathway may be important in the tumorigenesis of KS and that rapamycin may have activity in this disease.	Potassium	102-104	mechanistic target of rapamycin kinase	Homo sapiens	48-52
18047304-5	2007	Analysis of the quenching data within the context of a gas kinetic, strong collision model allows an estimate of the rate constant for HCN production via DMP photodissociation, ks = 4.1 x 10(3), 1.0 x 10(3), and 1.3 x 10(4) s(-1) for 2,3-, 2,5- and 2,6-DMP, respectively.	Potassium	177-179	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	135-138
18020321-0	2007	K-39 quadrupolar and chemical shift tensors for organic potassium complexes and diatomic molecules.	Potassium	56-65	keratin 39	Homo sapiens	0-4
17962323-0	2007	TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.	Potassium	83-92	potassium channel, subfamily K, member 18	Mus musculus	0-5
18028884-4	2007	Here, we demonstrate that transfection of VMAT2 in the dopaminergic cell line, PC12, increases intracellular dopamine content, augments potassium-induced dopamine release and attenuates cell death induced by the cytosolic dopamine enhancer, methamphetamine, suggesting an enhancement in vesicular dopamine storage.	Potassium	136-145	solute carrier family 18 member A2	Rattus norvegicus	42-47
17962323-1	2007	TRESK (TWIK-related spinal cord K(+) channel) is the most recently identified member of the two-pore-domain potassium channel (K(2P)) family, the molecular source of background potassium currents.	Potassium	108-117	potassium channel, subfamily K, member 18	Mus musculus	0-5
17962323-1	2007	TRESK (TWIK-related spinal cord K(+) channel) is the most recently identified member of the two-pore-domain potassium channel (K(2P)) family, the molecular source of background potassium currents.	Potassium	108-117	potassium channel, subfamily K, member 18	Mus musculus	7-44
18004877-1	2007	The functional localization of potassium inward rectifiers is regulated by SAP97, a PDZ membrane-associated guanylate kinase protein.	Potassium	31-40	discs large MAGUK scaffold protein 1	Homo sapiens	75-80
17977674-0	2007	Peroxynitrite donor impairs excitability of hippocampal CA1 neurons by inhibiting voltage-gated potassium currents.	Potassium	96-105	carbonic anhydrase 1	Homo sapiens	56-59
17977674-3	2007	The aim of this study was to investigate the actions of ONOO(-) on voltage-activated potassium currents and its effect on membrane excitability in hippocampal CA1 neurons.	Potassium	85-94	carbonic anhydrase 1	Homo sapiens	159-162
17977674-4	2007	SIN-1(3-morpholino-sydnonimine), which leads to the simultaneous generation of superoxide anion and NO, and then forms the highly reactive species ONOO(-), induced a dose-dependent inhibition in amplitudes of transient potassium currents (I(A)) and delayed rectifier potassium currents (I(K)).	Potassium	219-228	MAPK associated protein 1	Homo sapiens	0-5
18029910-5	2007	Similarly, lowering of extracellular potassium concentration inhibited TNF-alpha-induced TF protein expression.	Potassium	37-46	tumor necrosis factor	Homo sapiens	71-80
17803675-0	2007	Distribution of potassium ion and water permeable channels at perivascular glia in brain and retina of the Large(myd) mouse.	Potassium	16-25	LARGE xylosyl- and glucuronyltransferase 1	Mus musculus	113-116
18056581-2	2007	For FHM, three genes have been identified encoding subunits of a calcium channel (CACNA1A), a sodium-potassium pump (ATP1A2), and a sodium channel (SCN1A).	Potassium	101-110	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	82-89
18056581-2	2007	For FHM, three genes have been identified encoding subunits of a calcium channel (CACNA1A), a sodium-potassium pump (ATP1A2), and a sodium channel (SCN1A).	Potassium	101-110	ATPase Na+/K+ transporting subunit alpha 2	Homo sapiens	117-123
17854348-1	2007	We studied the changes occurring in the membrane environment of prion protein (PrP) during apoptosis induced by low potassium in primary rat cerebellar neurons.	Potassium	116-125	prion protein	Rattus norvegicus	79-82
17981874-3	2007	In this study we observed extensive transcriptome reprogramming in healthy fou2 leaves closely resembling that induced by treatment with methyl jasmonate, biotic stresses and the potassium starvation response.	Potassium	179-188	two-pore channel 1	Arabidopsis thaliana	75-79
17854348-7	2007	Upon low potassium treatment, 20% of the PrP originally present in the detergent-resistant fraction was immunoprecipitated, together with 19% of sphingolipids and 22% of cholesterol.	Potassium	9-18	prion protein	Rattus norvegicus	41-44
17804457-0	2007	Regulation of the basolateral chloride/base exchangers AE1 and SLC26A7 in the kidney collecting duct in potassium depletion.	Potassium	104-113	solute carrier family 4 member 1 (Diego blood group)	Rattus norvegicus	55-58
17804457-0	2007	Regulation of the basolateral chloride/base exchangers AE1 and SLC26A7 in the kidney collecting duct in potassium depletion.	Potassium	104-113	solute carrier family 26 member 7	Rattus norvegicus	63-70
17804457-7	2007	The post translational increase in SLC26A7 membrane abundance in potassium depletion was recapitulated in vitro using epitope-tagged SLC26A7.	Potassium	65-74	solute carrier family 26 member 7	Rattus norvegicus	35-42
17804457-7	2007	The post translational increase in SLC26A7 membrane abundance in potassium depletion was recapitulated in vitro using epitope-tagged SLC26A7.	Potassium	65-74	solute carrier family 26 member 7	Rattus norvegicus	133-140
17916113-0	2007	Potassium transport systems in the moss Physcomitrella patens: pphak1 plants reveal the complexity of potassium uptake.	Potassium	0-9	Pphak1	Physcomitrella patens	63-69
17916113-0	2007	Potassium transport systems in the moss Physcomitrella patens: pphak1 plants reveal the complexity of potassium uptake.	Potassium	102-111	Pphak1	Physcomitrella patens	63-69
17996119-8	2007	The viability of microbial cells treated with MUC7 12-mer in the presence of sodium or potassium was also determined by killing assay or flow cytometry.	Potassium	87-96	mucin 7, secreted	Homo sapiens	46-50
17919187-5	2007	We found that nuclear SREBP-1c has a negative impact on both glucose- and potassium-stimulated insulin secretion as determined in islets from beta-cell-specific SREBP-1c transgenic mice as well as SREBP-1c knockout mice.	Potassium	74-83	sterol regulatory element binding transcription factor 1	Mus musculus	22-30
18058481-12	2007	The levels of potassium were found to be significantly lower among patients receiving diuretics than those receiving one of the other four drug categories of antihypertensive (p &lt; 0.05 for beta-blockers, ACE inhibitors, and CCBs; p &lt; 0.001 for ARBs).	Potassium	14-23	angiotensin I converting enzyme	Homo sapiens	207-210
18001287-6	2007	Throughout the cochlea, we found PKC beta II expression in the Hensen cells, non-sensory cells involved in potassium re-cycling, and lateral efferent terminals of the inner spiral bundle.	Potassium	107-116	phospholipase C, beta 2	Rattus norvegicus	33-44
17764516-10	2007	Thus, TPK1 seems to provide for a Ca(2+)- and 14-3-3-sensitive mechanism capable of controlling cytoplasmic potassium homeostasis in plants.	Potassium	108-117	thiamin pyrophosphokinase1	Arabidopsis thaliana	6-10
17699694-4	2007	We find that although the plateau potentials are mediated by a voltage-gated Ca(2+) current, they do not depend on the accumulation of cytosolic Ca(2+), then use a computational model to test the hypothesis that the slowly voltage-activated ether-a-go-go-related gene (ERG) potassium current repolarizes the plateaus.	Potassium	274-283	ETS transcription factor ERG	Homo sapiens	241-267
17531350-3	2007	We now report that sublethal doses of hydrogen peroxide attenuated IGF-1 neuroprotective activity on cultured cerebellar granule neurons under potassium and serum deprivation.	Potassium	143-152	insulin like growth factor 1	Homo sapiens	67-72
18064068-1	2007	The ATP-sensitive potassium (K(ATP)) channels which extensively distribute in diverse tissues (e.g. vascular smooth muscle, cardiac cells, and pancreas) are well-established for characteristics like vasodilatation, myocardial protection against ischemia, and insulin secretion.	Potassium	18-27	insulin	Homo sapiens	259-266
17428807-0	2007	dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons.	Potassium	69-78	harakiri, BCL2 interacting protein	Homo sapiens	0-3
17942730-0	2007	Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation.	Potassium	86-95	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	25-31
17428807-0	2007	dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons.	Potassium	69-78	harakiri, BCL2 interacting protein	Homo sapiens	4-7
17428807-1	2007	In cerebellar granule neurons, a BH3-only Bcl-2 family member, death protein 5/harakiri, is up-regulated in a JNK-dependent manner during apoptosis induced by potassium deprivation.	Potassium	159-168	BCL2 apoptosis regulator	Homo sapiens	42-47
17673464-3	2007	Kv1.5 is an important voltage-gated K(+) channel in the cardiovascular system underlying the ultra-rapid rectifying potassium current (Ik(ur)), a major repolarizing current in atrial myocytes, and regulating the resting membrane potential and excitability of smooth muscle cells.	Potassium	116-125	potassium voltage-gated channel, shaker-related subfamily, member 5	Mus musculus	0-5
17428807-1	2007	In cerebellar granule neurons, a BH3-only Bcl-2 family member, death protein 5/harakiri, is up-regulated in a JNK-dependent manner during apoptosis induced by potassium deprivation.	Potassium	159-168	harakiri, BCL2 interacting protein	Homo sapiens	63-78
17428807-1	2007	In cerebellar granule neurons, a BH3-only Bcl-2 family member, death protein 5/harakiri, is up-regulated in a JNK-dependent manner during apoptosis induced by potassium deprivation.	Potassium	159-168	harakiri, BCL2 interacting protein	Homo sapiens	79-87
17428807-3	2007	Here, we showed that the up-regulation of dp5, but not fas ligand and bim, after potassium deprivation was suppressed by the expression of a dominant negative form of c-Jun.	Potassium	81-90	harakiri, BCL2 interacting protein	Homo sapiens	42-45
17428807-3	2007	Here, we showed that the up-regulation of dp5, but not fas ligand and bim, after potassium deprivation was suppressed by the expression of a dominant negative form of c-Jun.	Potassium	81-90	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	167-172
17428807-4	2007	Deletion analysis of the 5"-flanking sequence of the dp5 gene revealed that a major responsive element responsible for the induction by potassium deprivation is an ATF binding site located at -116 to -109 relative to the transcriptional start site.	Potassium	136-145	harakiri, BCL2 interacting protein	Homo sapiens	53-56
17428807-4	2007	Deletion analysis of the 5"-flanking sequence of the dp5 gene revealed that a major responsive element responsible for the induction by potassium deprivation is an ATF binding site located at -116 to -109 relative to the transcriptional start site.	Potassium	136-145	glial cell derived neurotrophic factor	Homo sapiens	164-167
17428807-6	2007	Furthermore, a gel shift assay showed that a specific complex containing c-Jun and ATF2 recognized this site and increased in potassium-deprived cerebellar granule neurons.	Potassium	126-135	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	73-78
17428807-6	2007	Furthermore, a gel shift assay showed that a specific complex containing c-Jun and ATF2 recognized this site and increased in potassium-deprived cerebellar granule neurons.	Potassium	126-135	activating transcription factor 2	Homo sapiens	83-87
17428807-8	2007	Finally, we demonstrated that knockdown of Dp5 by small interfering RNA rescued neurons from potassium deprivation-induced apoptosis.	Potassium	93-102	harakiri, BCL2 interacting protein	Homo sapiens	43-46
17428807-9	2007	Taken together, these results suggest that dp5 is a target gene of c-Jun and plays a critical role in potassium deprivation-induced apoptosis in cerebellar granule neurons.	Potassium	102-111	harakiri, BCL2 interacting protein	Homo sapiens	43-46
17845569-4	2007	ACE-inhibitor or ARB use resulted in a lower hematocrit (-3.5%; 95% CI -6.1 to -0.95), reduction in proteinuria (-0.47 gm/d; 95% CI -0.86 to -0.08) but no change in the serum potassium (0.18 mmol/L; 95% CI -0.03 to 0.40).	Potassium	175-184	angiotensin I converting enzyme	Homo sapiens	0-3
17845044-4	2007	Treatment of 5-8 with 2 equiv of potassium in THF resulted in the novel heteroleptic silylene [{PhC(NBu(t))2}SiR] [R = NMe2 (9), OBu(t) (10), OPr(i) (11), PPr(i)2 (12)].	Potassium	33-42	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	119-123
17845044-4	2007	Treatment of 5-8 with 2 equiv of potassium in THF resulted in the novel heteroleptic silylene [{PhC(NBu(t))2}SiR] [R = NMe2 (9), OBu(t) (10), OPr(i) (11), PPr(i)2 (12)].	Potassium	33-42	PPR1	Homo sapiens	155-158
17643200-7	2007	CONCLUSIONS/INTERPRETATION: We show here that cAMP elevation directly triggers GLP-1 release and enhances the secretory response to other stimuli like glucose, by modulating hyperpolarisation-activated currents and the background potassium current.	Potassium	230-239	glucagon	Mus musculus	79-84
17939752-0	2007	Application of PatchXpress planar patch clamp technology to the screening of new drug candidates for cardiac KCNQ1/KCNE1 (I Ks) activity.	Potassium	124-126	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	109-114
17939752-0	2007	Application of PatchXpress planar patch clamp technology to the screening of new drug candidates for cardiac KCNQ1/KCNE1 (I Ks) activity.	Potassium	124-126	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	115-120
17939752-8	2007	Electrophysiological recording of I Ks expressed in HEK-293 cells with the PatchXpress is of acceptable quality for screening purposes.	Potassium	36-38	EPH receptor A3	Homo sapiens	52-55
17804190-3	2007	Serum and potassium deprivation induced cerebellar granule neurons to undergo apoptosis, which correlated with the activation of caspase-3.	Potassium	10-19	caspase 3	Homo sapiens	129-138
17906162-7	2007	In the HCTZ + DRSP/E2 group, serum potassium, aldosterone, and plasma renin activity all increased in a manner marginally consistent with a beneficial antialdosterone effect, counteracting the HCTZ-induced potassium loss and lowering both systolic and diastolic blood pressure.	Potassium	206-215	renin	Homo sapiens	70-75
17828261-6	2007	SNX27 promotes the endosomal movement of Kir3 channels, leading to reduced surface expression, increased degradation and smaller Kir3 potassium currents.	Potassium	134-143	sorting nexin 27	Homo sapiens	0-5
17909436-2	2007	BACKGROUND: GJB2, a gene encoding a gap junction protein expressed in the inner ear, has been suggested to be involved in the potassium recycling pathway in the cochlea.	Potassium	126-135	gap junction protein beta 2	Homo sapiens	12-16
17909436-4	2007	Other genes involved in potassium homeostasis have been suggested to be associated with ARHI and NIHL, and distortion product otoacoustic emission distortions indicative of hearing loss alterations have been found in 35delG carriers.	Potassium	24-33	DIRAS family GTPase 3	Homo sapiens	88-92
17922773-0	2007	Two calcineurin B-like calcium sensors, interacting with protein kinase CIPK23, regulate leaf transpiration and root potassium uptake in Arabidopsis.	Potassium	117-126	CBL-interacting protein kinase 23	Arabidopsis thaliana	72-78
17922773-7	2007	In addition, expression of the CIPK23 gene was induced by low-potassium conditions, implicating a function of this gene product in potassium nutrition.	Potassium	62-71	CBL-interacting protein kinase 23	Arabidopsis thaliana	31-37
17922773-7	2007	In addition, expression of the CIPK23 gene was induced by low-potassium conditions, implicating a function of this gene product in potassium nutrition.	Potassium	131-140	CBL-interacting protein kinase 23	Arabidopsis thaliana	31-37
17922773-8	2007	Indeed, cipk23 mutants displayed severe growth impairment on media with low concentrations of potassium.	Potassium	94-103	CBL-interacting protein kinase 23	Arabidopsis thaliana	8-14
17922773-10	2007	In support of the conclusion that CBL1 and CBL9 interact with and synergistically serve as upstream regulators of CIPK23, the cbl1 cbl9 double mutant, but not the cbl1 or cbl9 single mutants, exhibit altered phenotypes for stomatal responses and low-potassium sensitivity.	Potassium	250-259	Cbl proto-oncogene	Homo sapiens	126-135
17728064-2	2007	A key regulator of cell cycle, E2F1, was believed to play a role in CGN apoptosis induced by potassium deprivation.	Potassium	93-102	E2F transcription factor 1	Mus musculus	31-35
17728064-2	2007	A key regulator of cell cycle, E2F1, was believed to play a role in CGN apoptosis induced by potassium deprivation.	Potassium	93-102	cingulin	Mus musculus	68-71
17728064-3	2007	However, here we demonstrated that although E2F1 was upregulated in wild type CGNs following potassium deprivation, CGNs that derived from E2F1 knockout mice underwent apoptosis at a similar rate as the wild type.	Potassium	93-102	E2F transcription factor 1	Mus musculus	44-48
17624312-7	2007	Using whole-cell patch-clamp recording, the recombinant BmK86 was found to inhibit the potassium current of mKv1.3 channel expressed in COS7 cells.	Potassium	87-96	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	108-114
17599095-7	2007	Dimerization of ASC is driven by subphysiological concentrations of potassium as in vitro incubation of purified recombinant ASC in the presence of subphysiological concentrations of potassium induces the assembly of a functional pyroptosome.	Potassium	68-77	PYD and CARD domain containing	Homo sapiens	16-19
17877911-0	2007	Endothelin-1 inhibits outward potassium currents in mouse outer sulcus cells.	Potassium	30-39	endothelin 1	Mus musculus	0-12
17877911-3	2007	We investigated the electrical properties and the effects of endothelin-1 (ET-1) on the outward potassium currents in mouse outer sulcus cells using a whole-cell patch clamp technique.	Potassium	96-105	endothelin 1	Mus musculus	61-73
17877911-3	2007	We investigated the electrical properties and the effects of endothelin-1 (ET-1) on the outward potassium currents in mouse outer sulcus cells using a whole-cell patch clamp technique.	Potassium	96-105	endothelin 1	Mus musculus	75-79
17877911-7	2007	Application of ET-1 caused a decrease of outward potassium currents within seconds, whereas treatment with BQ123, a competitive inhibitor of the ET type-A receptor, counteracted the inhibitory effect of ET-1.	Potassium	49-58	endothelin 1	Mus musculus	15-19
17877911-8	2007	These results suggest that ET-1 inhibits outward potassium currents through the activation of ET type-A receptor.	Potassium	49-58	endothelin 1	Mus musculus	27-31
17599095-7	2007	Dimerization of ASC is driven by subphysiological concentrations of potassium as in vitro incubation of purified recombinant ASC in the presence of subphysiological concentrations of potassium induces the assembly of a functional pyroptosome.	Potassium	68-77	PYD and CARD domain containing	Homo sapiens	125-128
17599095-7	2007	Dimerization of ASC is driven by subphysiological concentrations of potassium as in vitro incubation of purified recombinant ASC in the presence of subphysiological concentrations of potassium induces the assembly of a functional pyroptosome.	Potassium	183-192	PYD and CARD domain containing	Homo sapiens	16-19
17599095-7	2007	Dimerization of ASC is driven by subphysiological concentrations of potassium as in vitro incubation of purified recombinant ASC in the presence of subphysiological concentrations of potassium induces the assembly of a functional pyroptosome.	Potassium	183-192	PYD and CARD domain containing	Homo sapiens	125-128
17599095-8	2007	Furthermore, stimulation of potassium efflux in THP-1 cells with potassium-depleting agents induces formation of the pyroptosome, while increasing potassium concentrations in the culture medium or pharmacological inhibition of this efflux inhibits its assembly.	Potassium	28-37	GLI family zinc finger 2	Homo sapiens	48-53
17767909-1	2007	Voltage-gated potassium currents (Kv), primarily due to Kv2.1 channels, are activated by glucose-stimulated pancreatic beta cell depolarization, but the exact role (or roles) of this channel in regulating insulin secretion remains uncertain.	Potassium	14-23	potassium voltage gated channel, Shab-related subfamily, member 1	Mus musculus	56-61
17599095-8	2007	Furthermore, stimulation of potassium efflux in THP-1 cells with potassium-depleting agents induces formation of the pyroptosome, while increasing potassium concentrations in the culture medium or pharmacological inhibition of this efflux inhibits its assembly.	Potassium	65-74	GLI family zinc finger 2	Homo sapiens	48-53
17599095-8	2007	Furthermore, stimulation of potassium efflux in THP-1 cells with potassium-depleting agents induces formation of the pyroptosome, while increasing potassium concentrations in the culture medium or pharmacological inhibition of this efflux inhibits its assembly.	Potassium	65-74	GLI family zinc finger 2	Homo sapiens	48-53
17693758-5	2007	ROMK-/- and wild-type mice on a high potassium diet exhibit BK-mediated potassium secretion, and studies of BK-alpha-/- and BK-beta1-/- mice suggest that flow-induced potassium secretion is mediated by BK-alpha/beta1, which is specifically localized in the apical membrane of the connecting tubule of the mouse and connecting tubule plus initial cortical collecting duct of the rabbit.	Potassium	72-81	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	0-4
17693758-5	2007	ROMK-/- and wild-type mice on a high potassium diet exhibit BK-mediated potassium secretion, and studies of BK-alpha-/- and BK-beta1-/- mice suggest that flow-induced potassium secretion is mediated by BK-alpha/beta1, which is specifically localized in the apical membrane of the connecting tubule of the mouse and connecting tubule plus initial cortical collecting duct of the rabbit.	Potassium	72-81	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	0-4
17676365-7	2007	Rat and mouse presented different rank orders (e.g., GPR55 generated the greatest Ka/Ks ratio).	Potassium	85-87	G protein-coupled receptor 55	Mus musculus	53-58
17581850-4	2007	Under voltage clamp (V H -65 mV), 22/24 motoneurons displayed a CCK-8s-induced tetrodotoxin-resistant inward current [peak: -136 +/- 28 pA] with a similar time course, mediated via reduction in a potassium conductance.	Potassium	196-205	cholecystokinin	Rattus norvegicus	64-67
17767702-7	2007	Similarly, in striatal cultures, the D(2)-selective agonist quinpirole inhibited potassium-stimulated ERK1/2 phosphorylation, indicating the presence of this pathway in neurons.	Potassium	81-90	mitogen activated protein kinase 3	Rattus norvegicus	102-108
17590357-0	2007	Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential.	Potassium	124-133	ETS transcription factor ERG	Homo sapiens	119-123
17918144-1	2007	Even though there are some functional similarities between the aged kidney and the chronically damaged one, such as the reduction in glomerular filtration rate and in the sodium-water reabsorption capability, there are many physiological differences between these two groups, as is the case of erythropoietin, urea, potassium, calcium, phosphorus and magnesium renal handling.	Potassium	316-325	erythropoietin	Homo sapiens	294-308
17710648-2	2007	We characterized the role of endocytosis in lipid uptake from HDL, mediated by the human SR-BI, using a variety of approaches to inhibit endocytosis, including hypertonic shock, potassium or energy depletion and disassembly of the actin cytoskeleton.	Potassium	178-187	scavenger receptor class B member 1	Homo sapiens	89-94
17595326-3	2007	The MiRP2-Kv3.4 channel complex-previously found to be important in skeletal myocyte physiology-is now argued to be a molecular correlate of the transient outward potassium current up-regulated by Abeta peptide, considered a significant step in the etiology of Alzheimer"s disease.	Potassium	163-172	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	4-9
17763995-3	2007	At the same time, leucine-enkephalin produced reversible increases in the amplitude of the inward potassium current.	Potassium	98-107	proenkephalin	Rattus norvegicus	26-36
17763995-4	2007	These results provide evidence that the inhibitory effect of leucine-enkephalin at the level of respiratory center neurons is at least in part explained by its stimulatory action on the inward potassium current but is not associated with modulation of the potassium A current.	Potassium	193-202	proenkephalin	Rattus norvegicus	69-79
17970538-2	2007	The appropriate intake of fats, fibre, and minerals (sodium, calcium, magnesium, potassium) in their diets; may reduce the risk to develop hypertension and cardiovascular diseases, in the long-term.	Potassium	81-90	chromosome 10 open reading frame 90	Homo sapiens	26-30
17897250-4	2007	Intravenous insulin and nebulized albuterol lower serum potassium acutely, by shifting it into the cells.	Potassium	56-65	insulin	Homo sapiens	12-19
17595326-3	2007	The MiRP2-Kv3.4 channel complex-previously found to be important in skeletal myocyte physiology-is now argued to be a molecular correlate of the transient outward potassium current up-regulated by Abeta peptide, considered a significant step in the etiology of Alzheimer"s disease.	Potassium	163-172	potassium voltage-gated channel subfamily C member 4	Homo sapiens	10-15
17595326-3	2007	The MiRP2-Kv3.4 channel complex-previously found to be important in skeletal myocyte physiology-is now argued to be a molecular correlate of the transient outward potassium current up-regulated by Abeta peptide, considered a significant step in the etiology of Alzheimer"s disease.	Potassium	163-172	amyloid beta precursor protein	Homo sapiens	197-202
17466509-3	2007	The immobilized superoxide dismutase realized direct electron transfer between the enzyme and electrode surface, and the rate constants of the electrochemical process (ks) of SOD was markedly enhanced by GNPs.	Potassium	168-170	superoxide dismutase 1	Homo sapiens	16-36
17466509-3	2007	The immobilized superoxide dismutase realized direct electron transfer between the enzyme and electrode surface, and the rate constants of the electrochemical process (ks) of SOD was markedly enhanced by GNPs.	Potassium	168-170	superoxide dismutase 1	Homo sapiens	175-178
17569742-9	2007	In voltage clamp, the CCK-8s-induced inward current reversed at -106 +/- 3 mV and the input resistance increased by 150 +/- 15%, suggesting an effect mediated by the closure of a potassium conductance.	Potassium	179-188	cholecystokinin	Rattus norvegicus	22-25
17443681-1	2007	In cardiac cells, KCNQ1 assembles with KCNE1 and forms a channel complex constituting the slow delayed rectifier current I(Ks).	Potassium	123-125	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	18-23
17679033-10	2007	Adiponectin levels were inversely correlated with HOMA index and positively correlated with potassium levels both in primary aldosteronism (P&lt;.001) or in LREH (P&lt;.05) groups.	Potassium	92-101	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
17512706-5	2007	Careful measurements indicate the Tet1.5 G-wires orient along the b lattice vector of mica, the next nearest neighbor potassium vacancy.	Potassium	118-127	tet methylcytosine dioxygenase 1	Homo sapiens	34-38
17443681-1	2007	In cardiac cells, KCNQ1 assembles with KCNE1 and forms a channel complex constituting the slow delayed rectifier current I(Ks).	Potassium	123-125	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	39-44
17847714-7	2007	This approach provided values for the turnover and dissociation constant of the albumin-substrate complex: k(cat) = 0.13 +/- 0.02 min(-1) and Ks = 0.67 +/- 0.04 mM.	Potassium	142-144	albumin	Homo sapiens	80-87
17581847-3	2007	We previously identified the inward rectifying K(+) channel Kir4.1 as the major K(+) conductance in spinal cord astrocytes in situ and hence hypothesized that different expression levels of Kir4.1 may account for the observed differences in potassium dynamics in spinal cord.	Potassium	241-250	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	60-66
17581847-3	2007	We previously identified the inward rectifying K(+) channel Kir4.1 as the major K(+) conductance in spinal cord astrocytes in situ and hence hypothesized that different expression levels of Kir4.1 may account for the observed differences in potassium dynamics in spinal cord.	Potassium	241-250	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	190-196
17581847-9	2007	Taken together, these data support the conclusion that regional differences in astrocytic expression of Kir4.1 channels result in marked changes in potassium clearance rates in these two regions of the spinal cord.	Potassium	148-157	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	104-110
17612578-1	2007	Recent studies have demonstrated that neuronal reentry in the cell cycle and specifically the expression of the transcription factor E2F-1, constitutes a pathway that may be involved in neuronal apoptosis after serum and potassium withdrawal.	Potassium	221-230	E2F transcription factor 1	Rattus norvegicus	133-138
17612578-4	2007	CGNs showed a dramatic increase in GSK-3beta activity after 2h of serum and potassium deprivation.	Potassium	76-85	glycogen synthase kinase 3 beta	Rattus norvegicus	35-44
17582781-0	2007	Blockade action of ketanserin and increasing effect of potassium ion on Kv1.3 channels expressed in Xenopus oocytes.	Potassium	55-64	potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog	Xenopus laevis	72-77
17321804-3	2007	We then demonstrated with patch clamping technique that extracellular application of IL-1beta dose-dependently inhibited the outward voltage-dependent and TEA-sensitive potassium currents (I(K)) in the PC12 cells, and pre-incubation with the interleukin-1 receptor antagonist almost completely abolished this inhibitory effect.	Potassium	169-178	interleukin 1 beta	Rattus norvegicus	85-93
17337591-0	2007	TNF-alpha downregulates transient outward potassium current in rat ventricular myocytes through iNOS overexpression and oxidant species generation.	Potassium	42-51	tumor necrosis factor	Rattus norvegicus	0-9
17583434-11	2007	Furthermore, serum potassium withdrawal increases the expression of SIRT1.	Potassium	19-28	sirtuin 1	Homo sapiens	68-73
17477915-0	2007	Reduction of hERG potassium currents by hyperosmolar solutions.	Potassium	18-27	ETS transcription factor ERG	Homo sapiens	13-17
17477915-1	2007	We investigated the effects of hyperosmolar solutions on human ether-a-go-go related gene (hERG) potassium currents in chinese hamster ovary (CHO) cells.	Potassium	97-106	ETS transcription factor ERG	Homo sapiens	91-95
17337591-0	2007	TNF-alpha downregulates transient outward potassium current in rat ventricular myocytes through iNOS overexpression and oxidant species generation.	Potassium	42-51	nitric oxide synthase 2	Rattus norvegicus	96-100
17699488-6	2007	In patients with primary aldosteronism, plasma active renin levels that were higher than the lower limit of detection (2.5 pg/ml) were associated with higher BP, plasma potassium, and albuminuria and lower creatinine clearance.	Potassium	169-178	renin	Homo sapiens	54-59
17449550-5	2007	Both the angiotensin-converting enzyme inhibitor captopril and the AT(1)R antagonist losartan prevented the OVX-induced decrease in the FE(K(+)) and the increase in renal AT(1)R densities, suggesting that E(2) deficiency reduces potassium excretion in an ANG II/AT(1)R-dependent manner.	Potassium	229-238	angiotensin II receptor type 1	Homo sapiens	67-73
18708742-0	2007	Regulation of Kv4.3 closed state inactivation and recovery by extracellular potassium and intracellular KChIP2b.	Potassium	76-85	potassium voltage-gated channel subfamily D member 3	Homo sapiens	14-19
17579551-14	2007	The differentiated SGP cells could release insulin, which were stimulated by glucose and potassium.	Potassium	89-98	insulin	Sus scrofa	43-50
17659475-1	2007	Two-pore domain potassium (K2P) channels are expressed in cells throughout the body and give rise to leak potassium currents which control the excitability of these cells.	Potassium	16-25	keratin 76	Homo sapiens	27-30
17499934-6	2007	Our results showed that Abeta, the main component of senile plaques, caused ultrastructural changes indicative of impaired synaptic vesicle endocytosis in cultured hippocampal neurons that have been stimulated by depolarization with high potassium.	Potassium	238-247	amyloid beta precursor protein	Homo sapiens	24-29
17462767-3	2007	GJB2 encodes the gap junction protein Connexin26, which plays a crucial role in potassium recycling in the inner ear.	Potassium	80-89	gap junction protein, beta 2	Mus musculus	0-4
17462767-3	2007	GJB2 encodes the gap junction protein Connexin26, which plays a crucial role in potassium recycling in the inner ear.	Potassium	80-89	gap junction protein, beta 2	Mus musculus	38-48
17616977-9	2007	The coding region of hydra has a relatively high Ka/Ks ratio between species, but the ratio is less than 1 in all comparisons, suggesting that hydra is subject to functional constraint.	Potassium	52-54	hydra	Drosophila melanogaster	21-26
17544586-1	2007	Depolarization of 7-8-day-old mouse cerebellar granule neurons in primary cultures, a glutamatergic preparation, by elevation of the extracellular potassium ion concentration ([K+]e) to 45 mM induces an increase of phosphorylation of extracellular-signal regulated kinase 1 and 2 (ERK1/2) at two time periods: 20 min and 60 min after the [K+]e increase.	Potassium	147-156	mitogen-activated protein kinase 3	Mus musculus	234-279
17544586-1	2007	Depolarization of 7-8-day-old mouse cerebellar granule neurons in primary cultures, a glutamatergic preparation, by elevation of the extracellular potassium ion concentration ([K+]e) to 45 mM induces an increase of phosphorylation of extracellular-signal regulated kinase 1 and 2 (ERK1/2) at two time periods: 20 min and 60 min after the [K+]e increase.	Potassium	147-156	mitogen-activated protein kinase 3	Mus musculus	281-287
17379638-0	2007	Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons.	Potassium	42-51	potassium voltage-gated channel subfamily A member 6	Rattus norvegicus	0-3
17554004-0	2007	Inhibition of resting potassium conductances by long-term activation of the NO/cGMP/protein kinase G pathway: a new mechanism regulating neuronal excitability.	Potassium	22-31	protein kinase cGMP-dependent 1	Homo sapiens	84-100
17554162-0	2007	Purification, crystallization and structure determination of native GroEL from Escherichia coli lacking bound potassium ions.	Potassium	110-119	GroEL	Escherichia coli	68-73
17506935-3	2007	We aimed to study whether changes in the expression of FKBP12.6 and SERCA2a and the endothelin (ET) system on reperfusion against ischemia were related to the rapid occurrence of VF and whether CPU86017, a class III antiarrhythmic agent which blocks I(Kr), I(Ks), and I(Ca.L), suppressed VF by correcting the molecular changes on reperfusion.	Potassium	259-261	FKBP prolyl isomerase 1B	Rattus norvegicus	55-63
17554162-4	2007	The complex was purified and crystallized in the absence of potassium ions, which allowed evaluation of the structural changes that may occur in response to cognate potassium-ion binding by comparison to the previously determined wild-type GroEL structure (PDB code 1xck), in which potassium ions were observed in all 14 subunits.	Potassium	165-174	GroEL	Escherichia coli	240-245
17554162-4	2007	The complex was purified and crystallized in the absence of potassium ions, which allowed evaluation of the structural changes that may occur in response to cognate potassium-ion binding by comparison to the previously determined wild-type GroEL structure (PDB code 1xck), in which potassium ions were observed in all 14 subunits.	Potassium	165-174	GroEL	Escherichia coli	240-245
17303683-8	2007	These results indicate that a decrease in potassium conductance is likely the main ionic mechanism underlying the leptin-induced depolarization.	Potassium	42-51	leptin	Rattus norvegicus	114-120
17604458-10	2007	As examples, the clinician may recommend vitamin K and potassium to reduce hypercalciuria, _-lipoic acid and N-acetylcysteine to reduce the bone resorption marker N-telopeptide (N-Tx), and dehydroepiandrosterone (DHEA), whey, and milk basic protein (the basic protein fraction of whey) to increase insulin-like growth factor-1 (IGF-1) and create a more anabolic profile.	Potassium	55-64	insulin like growth factor 1	Homo sapiens	298-326
17604458-10	2007	As examples, the clinician may recommend vitamin K and potassium to reduce hypercalciuria, _-lipoic acid and N-acetylcysteine to reduce the bone resorption marker N-telopeptide (N-Tx), and dehydroepiandrosterone (DHEA), whey, and milk basic protein (the basic protein fraction of whey) to increase insulin-like growth factor-1 (IGF-1) and create a more anabolic profile.	Potassium	55-64	insulin like growth factor 1	Homo sapiens	328-333
17303683-7	2007	The reversal potential of the leptin-induced inward current was shifted to a more positive potential level in a high-potassium medium.	Potassium	117-126	leptin	Rattus norvegicus	30-36
17303683-9	2007	On the other hand, the I-V curve of leptin-induced outward currents is characterized by positive slope conductance and has an average reversal potential of -88 +/- 3 mV, suggesting that an increase in potassium conductance may underlie leptin-induced hyperpolarization.	Potassium	201-210	leptin	Rattus norvegicus	36-42
17303683-9	2007	On the other hand, the I-V curve of leptin-induced outward currents is characterized by positive slope conductance and has an average reversal potential of -88 +/- 3 mV, suggesting that an increase in potassium conductance may underlie leptin-induced hyperpolarization.	Potassium	201-210	leptin	Rattus norvegicus	236-242
17610583-5	2007	The results from whole-cell patch-clamp recordings and calcium imaging showed that extracellular application of IL-1beta significantly decreased the outward potassium current and triggered a transient rise in [Ca(2+)](i) in the cultured glomus cells of rat CB.	Potassium	157-166	interleukin 1 beta	Rattus norvegicus	112-120
17322063-7	2007	Indeed, the GLP-1 effects were mediated by actions on potassium currents, GABA-induced currents, or both.	Potassium	54-63	glucagon	Homo sapiens	12-17
17347319-0	2007	Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter.	Potassium	92-101	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	26-31
17535874-6	2007	The 24-h urine excretion of sodium and potassium was increased in the LI-IGF-I(-/-) mice.	Potassium	39-48	insulin-like growth factor 1	Mus musculus	73-78
17535874-9	2007	In conclusion, deficiency of circulating liver-derived IGF-I in mice results, despite an increase in GH secretion, in a global symmetrical decrease in kidney size, increased urinary sodium and potassium excretion, and a clear down regulation of renal IGF-II expression.	Potassium	193-202	insulin-like growth factor 1	Mus musculus	55-60
17363390-0	2007	Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits.	Potassium	19-28	ETS transcription factor ERG	Homo sapiens	14-18
17347319-0	2007	Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter.	Potassium	92-101	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	33-38
17374744-1	2007	The TASK subfamily of two pore domain potassium channels (K2P) gives rise to leak potassium currents, which contribute to the resting membrane potential of many neurons and regulate their excitability.	Potassium	38-47	keratin 76	Homo sapiens	58-61
17023080-1	2007	BACKGROUND: The most prevalent LQT1 form of inherited long QT syndrome is caused by mutations of the KCNQ1 gene resulting repolarizing I(Ks) potassium current to decrease and the QT interval to prolong.	Potassium	137-139	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	31-35
17490811-4	2007	Furthermore, the inhibition of ERK signaling increased A-type fast inactivating potassium current.	Potassium	80-89	Eph receptor B1	Rattus norvegicus	31-34
17490811-5	2007	Taken together, the excitation of CCD neurons might be attributed to the CCD-induced activation of ERK, which suppressed the A-type fast inactivating potassium conductance in CCD neurons.	Potassium	150-159	Eph receptor B1	Rattus norvegicus	99-102
17517644-7	2007	Immunocytochemistry showed that ING4 was expressed in the renal outer medullary potassium (ROMK)-positive tubules.	Potassium	80-89	inhibitor of growth family member 4	Homo sapiens	32-36
17517644-7	2007	Immunocytochemistry showed that ING4 was expressed in the renal outer medullary potassium (ROMK)-positive tubules.	Potassium	80-89	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	91-95
17023080-1	2007	BACKGROUND: The most prevalent LQT1 form of inherited long QT syndrome is caused by mutations of the KCNQ1 gene resulting repolarizing I(Ks) potassium current to decrease and the QT interval to prolong.	Potassium	137-139	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	101-106
17023080-1	2007	BACKGROUND: The most prevalent LQT1 form of inherited long QT syndrome is caused by mutations of the KCNQ1 gene resulting repolarizing I(Ks) potassium current to decrease and the QT interval to prolong.	Potassium	141-150	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	31-35
17023080-1	2007	BACKGROUND: The most prevalent LQT1 form of inherited long QT syndrome is caused by mutations of the KCNQ1 gene resulting repolarizing I(Ks) potassium current to decrease and the QT interval to prolong.	Potassium	141-150	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	101-106
17317746-4	2007	By using patch-clamp recordings from acute rat hippocampal slices we show that D-type potassium current modulates the size of the ADP and the bursting of CA1 pyramidal neurons.	Potassium	86-95	carbonic anhydrase 1	Rattus norvegicus	154-157
17382298-0	2007	Effects of PKC on inhibition of delayed rectifier potassium currents by N/OFQ.	Potassium	50-59	protein kinase C, gamma	Rattus norvegicus	11-14
17320039-5	2007	In hypotonic medium, magnesium and potassium ions have a protective effect on the release of enzymes and on the reactivity of cyto-c as electron acceptor from both sulfite and succinate; results which are consistent with the view that MOM preserves its identity and remains not permeable to exogenous cyto-c.	Potassium	35-44	cytochrome c, somatic	Homo sapiens	126-132
17244725-3	2007	Aldosterone levels were unchanged, whereas the plasma potassium concentration was elevated by 14% (P &lt; 0.05) in GHR KO.	Potassium	54-63	growth hormone receptor	Mus musculus	115-118
17515703-0	2007	The effects of quinidine and its chiral isolates on erg-1sm potassium current and correlation with gastrointestinal augmentation.	Potassium	60-69	potassium voltage-gated channel subfamily H member 2	Rattus norvegicus	52-57
17515703-3	2007	Studies were undertaken to evaluate the effects of quinidine and its chiral isolates on gastrointestinal erg1-sm potassium current and correlate these effects with colon contractility.	Potassium	113-122	potassium voltage-gated channel subfamily H member 2	Rattus norvegicus	105-109
17515703-11	2007	One chiral isolate and quinidine markedly augmented contractility, whereas quinidine and the two chiral isolates inhibited the erg1-sm potassium currents to a similar extent.	Potassium	135-144	potassium voltage-gated channel subfamily H member 2	Rattus norvegicus	127-131
17320039-5	2007	In hypotonic medium, magnesium and potassium ions have a protective effect on the release of enzymes and on the reactivity of cyto-c as electron acceptor from both sulfite and succinate; results which are consistent with the view that MOM preserves its identity and remains not permeable to exogenous cyto-c.	Potassium	35-44	cytochrome c, somatic	Homo sapiens	301-307
17486125-0	2007	CIPK9: a calcium sensor-interacting protein kinase required for low-potassium tolerance in Arabidopsis.	Potassium	68-77	CBL-interacting protein kinase 9	Arabidopsis thaliana	0-5
17486125-5	2007	We report here the identification of a calcineurin B-like protein-interacting protein kinase (CIPK9) as a critical regulator of low potassium response in Arabidopsis.	Potassium	132-141	CBL-interacting protein kinase 9	Arabidopsis thaliana	94-99
17350062-9	2007	These data demonstrated that potassium differentially enhanced the potency of PCB126 to induce CYP11B1- and CYP11B2-mediated steroidogenesis.	Potassium	29-38	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	95-102
17486125-6	2007	The CIPK9 gene was responsive to abiotic stress conditions, and its transcript was inducible in both roots and shoots by potassium deprivation.	Potassium	121-130	CBL-interacting protein kinase 9	Arabidopsis thaliana	4-9
17486125-7	2007	Disruption of CIPK9 function rendered the mutant plants hypersensitive to low potassium media.	Potassium	78-87	CBL-interacting protein kinase 9	Arabidopsis thaliana	14-19
17486125-8	2007	Further analysis indicated that K(+) uptake and content were not affected in the mutant plants, implying CIPK9 in the regulation of potassium utilization or sensing processes.	Potassium	132-141	CBL-interacting protein kinase 9	Arabidopsis thaliana	105-110
17350062-3	2007	Subsequent examinations revealed that CYP11B1 and CYP11B2 genes, responsible for the respective final steps of the cortisol and aldosterone biosynthetic pathways, exhibited increased responsiveness to PCB126 under high potassium.	Potassium	219-228	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	38-45
17350062-3	2007	Subsequent examinations revealed that CYP11B1 and CYP11B2 genes, responsible for the respective final steps of the cortisol and aldosterone biosynthetic pathways, exhibited increased responsiveness to PCB126 under high potassium.	Potassium	219-228	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	50-57
17350062-4	2007	While 10(-5) M PCB126 was needed to induce a significant increase in the basal mRNA abundance of either gene, PCB126 could enhance potassium-induced mRNA expression of CYP11B1 at 10(-7) M and CYP11B2 at 10(-9) M. Actually, potassium and PCB126 synergistically upregulated mRNA expression of both genes.	Potassium	131-140	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	168-175
17350062-4	2007	While 10(-5) M PCB126 was needed to induce a significant increase in the basal mRNA abundance of either gene, PCB126 could enhance potassium-induced mRNA expression of CYP11B1 at 10(-7) M and CYP11B2 at 10(-9) M. Actually, potassium and PCB126 synergistically upregulated mRNA expression of both genes.	Potassium	131-140	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	192-199
17350062-9	2007	These data demonstrated that potassium differentially enhanced the potency of PCB126 to induce CYP11B1- and CYP11B2-mediated steroidogenesis.	Potassium	29-38	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	108-115
17339832-2	2007	The slow component of delayed rectifier K(+) current (I (Ks)) is one of the major repolarizing currents in the hearts of many species and is also potentiated by PKC activation.	Potassium	57-59	Prkca	Cavia porcellus	161-164
17350062-5	2007	Potassium raised the transcriptional rates of CYP11B1 and CYP11B2 probably through a conserved Ad5 cis-element, whereas PCB126 appeared to regulate these two genes at the post-transcriptional level.	Potassium	0-9	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	46-53
17350062-5	2007	Potassium raised the transcriptional rates of CYP11B1 and CYP11B2 probably through a conserved Ad5 cis-element, whereas PCB126 appeared to regulate these two genes at the post-transcriptional level.	Potassium	0-9	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	58-65
17350062-7	2007	In contrast, potassium and PCB126 increased CYP11B1 enzyme activity or cortisol/17-OH-progesterone ratio additively.	Potassium	13-22	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	44-51
17350062-8	2007	Moreover, potassium improved the time effect of PCB126 on gene expression and enzyme activity of CYP11B2, but not the PCB126 time response of CYP11B1.	Potassium	10-19	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	97-104
17320053-6	2007	By comparison, high potassium caused a more dramatic decrease in cofilin and an immediate dendritic beading and loss of dendritic spines.	Potassium	20-29	cofilin 1	Homo sapiens	65-72
17371050-0	2007	Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function.	Potassium	104-113	acetyl-CoA acetyltransferase 1	Homo sapiens	46-84
17393393-1	2007	OBJECTIVE: We have previously described anti-KS autoantibodies and provided evidence that they are directed against asparaginyl-transfer RNA (tRNA) synthetase (AsnRS).	Potassium	45-47	asparaginyl-tRNA synthetase 2, mitochondrial	Homo sapiens	160-165
17339832-3	2007	Little is known, however, about PKC isoform(s) functionally involved in the potentiation of I (Ks) in native cardiac myocytes.	Potassium	95-97	Prkca	Cavia porcellus	32-35
17339832-10	2007	CONCLUSIONS AND IMPLICATIONS: The present study provides experimental evidence to suggest that, in native guinea-pig cardiac myocytes, activation of PKC contributes to alpha(1)-adrenoceptor-mediated potentiation of I (Ks) and that epsilon is the isoform predominantly involved in this PKC action.	Potassium	218-220	Prkca	Cavia porcellus	149-152
17289006-2	2007	In the heart, KCNQ1 alpha-subunits assemble with KCNE1 beta-subunits forming a channel complex constituting the delayed rectifier current I(Ks).	Potassium	140-142	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	14-19
17289006-2	2007	In the heart, KCNQ1 alpha-subunits assemble with KCNE1 beta-subunits forming a channel complex constituting the delayed rectifier current I(Ks).	Potassium	140-142	putative potassium voltage-gated channel subfamily E member 1B	Homo sapiens	49-59
17384445-8	2007	Prolongation of the APD and decrease in I(Ks) with increasing the amount of KCNE1 concentration were well predicted in a computer simulation.	Potassium	42-44	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	76-81
17289006-8	2007	In vivo expression of a catalytically inactive form of Nedd4-2, able to antagonize endogenous Nedd4-2 in guinea-pig cardiomyocytes, increased I(Ks) significantly, but did not modify I(K1).	Potassium	144-146	E3 ubiquitin-protein ligase NEDD4-like	Cavia porcellus	55-62
17058022-0	2007	Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents.	Potassium	74-83	prolactin	Homo sapiens	35-44
17194699-0	2007	Angiotensin II inhibits the ROMK-like small conductance K channel in renal cortical collecting duct during dietary potassium restriction.	Potassium	115-124	angiotensinogen	Rattus norvegicus	0-14
17556873-2	2007	Primary HypoPP is genetically determined, while secondary acquired HypoPP has been described in association with thyreotoxycosis, hyperaldosteronism, kidney diseases, diuretics and liquorice abuse, gastrointestinal potassium loss, or cysplatinum therapy.	Potassium	215-224	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	67-73
17254020-2	2007	In these cells, ERKs are activated by diverse stimuli, including cyclic adenosine monophosphate (cAMP), pituitary adenylate cyclase activating protein (PACAP), depolarization induced by elevated extracellular potassium (KCl), and the neurotrophin brain-derived neurotrophic factor.	Potassium	209-218	mitogen-activated protein kinase 1	Homo sapiens	16-20
17436794-2	2007	Blood potassium concentration is primarily under the control of cellular transfer, driven either by the acid basic equilibrium, the action of catecholamines and insulin, and secondarily by the kidney.	Potassium	6-15	insulin	Homo sapiens	161-168
17194699-2	2007	We used the patch clamp technique applied to split-open cortical collecting ducts (CCDs) isolated from rats fed a normal potassium (NK) or low potassium (LK) diet to test the hypothesis that AngII directly inhibits ROMK channel activity.	Potassium	143-152	angiotensinogen	Rattus norvegicus	191-196
17194699-10	2007	We conclude that AngII inhibits ROMK channel activity through PKC-, NADPH oxidase-, and PTK-dependent pathways under conditions of dietary potassium restriction.	Potassium	139-148	angiotensinogen	Rattus norvegicus	17-22
17465256-4	2007	RESULTS: Patients with methylation in p16(INK4a) consumed significantly less folate (p = 0.01), vitamin A (p = 0.01), vitamin B1 (p = 0.007), potassium (p = 0.03) and iron (p = 0.02) than controls.	Potassium	142-151	cyclin dependent kinase inhibitor 2A	Homo sapiens	38-41
17465256-4	2007	RESULTS: Patients with methylation in p16(INK4a) consumed significantly less folate (p = 0.01), vitamin A (p = 0.01), vitamin B1 (p = 0.007), potassium (p = 0.03) and iron (p = 0.02) than controls.	Potassium	142-151	cyclin dependent kinase inhibitor 2A	Homo sapiens	42-47
17432956-5	2007	A 2-h exposure to exogenous BDNF (100 ng/mL) had a significant effect on principal cell firing properties and voltage-gated potassium currents.	Potassium	124-133	brain derived neurotrophic factor	Mus musculus	28-32
17432956-7	2007	BDNF exposure also significantly decreased underlying voltage-gated potassium currents, including both the low- and high-voltage-activated components.	Potassium	68-77	brain derived neurotrophic factor	Mus musculus	0-4
17234684-3	2007	Generation of a valinomycin-mediated potassium-diffusion potential induced the reduction of cytochrome b in the reconstituted bc1 complex in the presence of sodium ascorbate.	Potassium	37-46	cytochrome b	Bos taurus	92-104
17188509-0	2007	Survival response-linked Pyk2 activation during potassium depletion-induced apoptosis of cerebellar granule neurons.	Potassium	48-57	protein tyrosine kinase 2 beta	Homo sapiens	25-29
17356517-1	2007	PURPOSE: The inwardly rectifying potassium channel protein Kir4.1 and the water channel protein aquaporin-4 (AQP4) have been suggested to play essential roles in the potassium and water homeostasis of the retina.	Potassium	33-42	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	59-65
17356517-16	2007	The differential expression of Kir4.1 and AQP4 during EIU implies a disturbance of water and potassium transport in the retina, which may contribute to the retinal edema during ocular inflammation.	Potassium	93-102	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	31-37
17356517-16	2007	The differential expression of Kir4.1 and AQP4 during EIU implies a disturbance of water and potassium transport in the retina, which may contribute to the retinal edema during ocular inflammation.	Potassium	93-102	aquaporin 4	Rattus norvegicus	42-46
17241518-0	2007	Activation of PI3-K/Akt pathway for thermal preconditioning to protect cultured cerebellar granule neurons against low potassium-induced apoptosis.	Potassium	119-128	AKT serine/threonine kinase 1	Rattus norvegicus	20-23
17103013-1	2007	SOS1 transporters from Cymodocea and Arabidopsis mediate potassium uptake in bacteria.	Potassium	57-66	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	0-4
17582287-7	2007	CONCLUSIONS: The uroguanylin G-247A polymorphism was associated with urinary volume and sodium and potassium excretions.	Potassium	99-108	guanylate cyclase activator 2B	Homo sapiens	17-28
17360683-0	2007	Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1.	Potassium	19-28	mitogen-activated protein kinase 14	Homo sapiens	53-56
17360683-0	2007	Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1.	Potassium	19-28	potassium voltage-gated channel subfamily B member 1	Homo sapiens	76-81
17360683-3	2007	Kv2.1, however, also provides the critical exit route for potassium ions during neuronal apoptosis via p38 MAPK-dependent membrane insertion, resulting in a pronounced enhancement of K(+) currents.	Potassium	58-67	potassium voltage-gated channel subfamily B member 1	Homo sapiens	0-5
17360683-3	2007	Kv2.1, however, also provides the critical exit route for potassium ions during neuronal apoptosis via p38 MAPK-dependent membrane insertion, resulting in a pronounced enhancement of K(+) currents.	Potassium	58-67	mitogen-activated protein kinase 14	Homo sapiens	103-106
17187762-3	2007	While phosphorylated eEF2 was weakly distributed in advancing growth cones, eEF2 phosphorylation was increased by high potassium-evoked calcium influx.	Potassium	119-128	eukaryotic translation elongation factor 2	Homo sapiens	76-80
17241518-1	2007	AIM: This study was designed to investigate whether the activation of the phosphatidylinositol 3-kinase (PI3-K)/Akt pathway is required for thermal preconditioning to protect rat cerebellar granule neurons (CGN) against apoptosis induced by low potassium, and to explore the possibility of a link between the upregulated heat shock protein (HSP)70 expression and Akt activation in the acquisition of neuroprotection induced by thermal preconditioning.	Potassium	245-254	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	Rattus norvegicus	74-103
17040965-0	2007	Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.	Potassium	49-58	potassium voltage-gated channel subfamily A member 5	Homo sapiens	0-5
17200954-8	2007	RESULTS: The pHi clamping conditions were optimized as 140 mM potassium and 10 microM nigericin.	Potassium	62-71	glucose-6-phosphate isomerase	Homo sapiens	13-16
17121744-7	2007	This uptake is followed by down regulation of inward-rectifying potassium (Kir 4.1) channels in astrocytes, resulting in reduced buffering of extracellular potassium.	Potassium	64-73	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	75-82
17331193-4	2007	Cells expressing myosin VIIa had larger potassium conductances and did not express the cyclin-dependent kinase inhibitor p27(kip1).	Potassium	40-49	myosin VIIA	Homo sapiens	17-28
17189489-0	2007	Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells.	Potassium	80-89	cation transporter	Saccharomyces cerevisiae S288C	58-62
17385313-13	2007	The mean Ka/Ks ratio for the SMC4 genes examined was 0.	Potassium	12-14	structural maintenance of chromosomes 4 L homeolog	Xenopus laevis	29-33
17091490-0	2007	Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes.	Potassium	43-52	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	18-24
17091490-4	2007	The purpose of the present study was to assess the role of the inward-rectifying K+ channel subunit Kir4.1 on potassium fluxes, glutamate uptake and membrane potential in cultured rat cortical astrocytes using RNAi, whole-cell patch clamp and a colorimetric assay.	Potassium	110-119	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	100-106
17091490-7	2007	The ability of Kir4.1-suppressed cells to mediate transmembrane potassium flow, as measured by the current response to voltage ramps or sequential application of different extracellular [K+], was dramatically impaired.	Potassium	64-73	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	15-21
17091490-9	2007	Together, these data indicate that Kir4.1 channels are primarily responsible for significant hyperpolarization of cortical astrocytes and are likely to play a major role in potassium buffering.	Potassium	173-182	potassium inwardly-rectifying channel, subfamily J, member 10	Rattus norvegicus	35-41
17227916-2	2007	MinK slows the activation of channels formed with KCNQ1 alpha subunits to generate the voltage-dependent I(Ks) channel in human heart; MiRP1 and MiRP2 remove the voltage dependence of KCNQ1 to generate potassium "leak" currents in gastrointestinal epithelia.	Potassium	202-211	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	135-140
17227916-2	2007	MinK slows the activation of channels formed with KCNQ1 alpha subunits to generate the voltage-dependent I(Ks) channel in human heart; MiRP1 and MiRP2 remove the voltage dependence of KCNQ1 to generate potassium "leak" currents in gastrointestinal epithelia.	Potassium	202-211	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	145-150
17227916-2	2007	MinK slows the activation of channels formed with KCNQ1 alpha subunits to generate the voltage-dependent I(Ks) channel in human heart; MiRP1 and MiRP2 remove the voltage dependence of KCNQ1 to generate potassium "leak" currents in gastrointestinal epithelia.	Potassium	202-211	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	184-189
17086548-0	2007	Role of brain-derived neurotrophic factor in the protective action of N-methyl-D-aspartate in the apoptotic death of cerebellar granule neurons induced by low potassium.	Potassium	159-168	brain-derived neurotrophic factor	Rattus norvegicus	8-41
17086548-5	2007	Here, we characterized the effect of BDNF and NMDA on the apoptotic death induced by low potassium in CGN.	Potassium	89-98	brain-derived neurotrophic factor	Rattus norvegicus	37-41
17086548-6	2007	Cell death of CGN by culturing in low potassium for 6 DIV was inhibited by BDNF and NMDA.	Potassium	38-47	brain-derived neurotrophic factor	Rattus norvegicus	75-79
17086548-9	2007	Both BDNF and NMDA decreased caspase-9 activity and mRNA caspase-3 levels and activity induced by low potassium.	Potassium	102-111	brain-derived neurotrophic factor	Rattus norvegicus	5-9
16773140-6	2007	These data suggest that activation of DOR protects the cortex against anoxia- or ODG-induced derangement of potassium homeostasis, and this protection occurs via a PKC-dependent and PKA-independent pathway.	Potassium	108-117	opioid receptor, delta 1	Mus musculus	38-41
17086548-9	2007	Both BDNF and NMDA decreased caspase-9 activity and mRNA caspase-3 levels and activity induced by low potassium.	Potassium	102-111	caspase 9	Rattus norvegicus	29-38
17086548-9	2007	Both BDNF and NMDA decreased caspase-9 activity and mRNA caspase-3 levels and activity induced by low potassium.	Potassium	102-111	caspase 3	Rattus norvegicus	57-66
17261195-0	2007	Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions.	Potassium	85-94	potassium voltage-gated channel subfamily A member 3	Homo sapiens	53-58
17187053-5	2007	This screen relies on the ability of KAT1, a eukaryotic Kv channel, to conduct potassium when its VSDs are in the down state, thereby rescuing potassium-transport-deficient yeast.	Potassium	79-88	histone acetyltransferase catalytic subunit HAT1	Saccharomyces cerevisiae S288C	37-41
17187053-5	2007	This screen relies on the ability of KAT1, a eukaryotic Kv channel, to conduct potassium when its VSDs are in the down state, thereby rescuing potassium-transport-deficient yeast.	Potassium	143-152	histone acetyltransferase catalytic subunit HAT1	Saccharomyces cerevisiae S288C	37-41
17067690-2	2007	Here we investigated effects of Ang II and potassium on the BMP system in human adrenocortical H295R cells.	Potassium	43-52	bone morphogenetic protein 6	Homo sapiens	60-63
17320698-8	2007	The postjunctional cholinergic pathway was specifically disrupted in caveolin-1 knockout animals because no difference was found in contractility between the knockout and wild type mice (young or old) when the bladders were stimulated by alpha,beta-methylene adenosine triphosphate or potassium.	Potassium	285-294	caveolin 1, caveolae protein	Mus musculus	69-79
17261195-4	2007	RESULTS: We employed the method of Monte Carlo (MC) with energy minimization to search for optimal complexes of correolide in Kv1.2-based models of the open Kv1.3 with potassium binding sites 2/4 or 1/3/5 loaded with K+ ions.	Potassium	168-177	potassium voltage-gated channel subfamily A member 2	Homo sapiens	126-131
17261195-4	2007	RESULTS: We employed the method of Monte Carlo (MC) with energy minimization to search for optimal complexes of correolide in Kv1.2-based models of the open Kv1.3 with potassium binding sites 2/4 or 1/3/5 loaded with K+ ions.	Potassium	168-177	potassium voltage-gated channel subfamily A member 3	Homo sapiens	157-162
17335661-14	2007	Further studies on the functional association between I(Ks) and KCNE4 (145D) polymorphism in cardiac myocytes are suggested.	Potassium	56-58	LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily E member 4	Cricetulus griseus	64-69
17251434-4	2007	By using an experimental model with either mouse organotypic spinal cultures or isolated spinal cord preparations, the present study examined the role of the ERG current (I(K(ERG))), a potassium conductance expressed by developing, GABA-immunoreactive spinal neurons.	Potassium	185-194	ETS transcription factor	Mus musculus	158-161
17150193-8	2007	This suggested that the OL in CA1 region could sense the neuronal activity and contribute to potassium clearance.	Potassium	93-102	carbonic anhydrase 1	Rattus norvegicus	30-33
17202481-2	2007	The circadian peak of VP gene transcription in the SCN in vitro is completely blocked by a 2 h exposure to tetrodotoxin (TTX) in the culture medium, and this TTX inhibition of VP gene transcription is reversed by exposure of the SCN to either forskolin or potassium depolarization.	Potassium	256-265	arginine vasopressin	Rattus norvegicus	22-24
17068099-1	2007	Leak potassium currents in the nervous system are often carried through two-pore-domain potassium (K2P) channels.	Potassium	5-14	keratin 76	Homo sapiens	99-102
17068101-0	2007	Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances.	Potassium	134-143	agouti related neuropeptide	Rattus norvegicus	18-40
16837648-0	2007	EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients.	Potassium	31-40	epidermal growth factor	Homo sapiens	0-3
16837648-0	2007	EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients.	Potassium	31-40	heparin binding EGF like growth factor	Homo sapiens	8-14
16837648-4	2007	A strongly inward rectifying potassium current with conductance of the Kir2.1 channel was identified in normal BUC.	Potassium	29-38	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	71-77
16837648-7	2007	Epidermal growth factor (EGF) caused a dose-dependent decrease in the inward potassium current in normal BUC.	Potassium	77-86	epidermal growth factor	Homo sapiens	0-23
16837648-7	2007	Epidermal growth factor (EGF) caused a dose-dependent decrease in the inward potassium current in normal BUC.	Potassium	77-86	epidermal growth factor	Homo sapiens	25-28
17202481-2	2007	The circadian peak of VP gene transcription in the SCN in vitro is completely blocked by a 2 h exposure to tetrodotoxin (TTX) in the culture medium, and this TTX inhibition of VP gene transcription is reversed by exposure of the SCN to either forskolin or potassium depolarization.	Potassium	256-265	arginine vasopressin	Rattus norvegicus	176-178
16837648-11	2007	These data show that the inward potassium current in BUC can be modulated by EGF and HB-EGF.	Potassium	32-41	epidermal growth factor	Homo sapiens	77-80
16882930-3	2007	We therefore studied the regulation of adrenal StAR mRNA expression in the context of dietary potassium-stimulated aldosterone production.	Potassium	94-103	steroidogenic acute regulatory protein	Rattus norvegicus	47-51
16837648-11	2007	These data show that the inward potassium current in BUC can be modulated by EGF and HB-EGF.	Potassium	32-41	heparin binding EGF like growth factor	Homo sapiens	85-91
16837648-12	2007	Changes in BUC membrane potassium conductance caused by altered levels of EGF and HB-EGF may therefore play a role in the pathophysiology of IC.	Potassium	24-33	epidermal growth factor	Homo sapiens	74-77
16837648-12	2007	Changes in BUC membrane potassium conductance caused by altered levels of EGF and HB-EGF may therefore play a role in the pathophysiology of IC.	Potassium	24-33	heparin binding EGF like growth factor	Homo sapiens	82-88
16882930-5	2007	The high-potassium diet increased StAR mRNA levels within the zona glomerulosa in both strains, as demonstrated by in situ hybridization.	Potassium	9-18	steroidogenic acute regulatory protein	Rattus norvegicus	34-38
16882930-9	2007	We conclude that an increase of StAR mRNA levels within the outer cortex is involved in the long-term adrenal response to potassium.	Potassium	122-131	steroidogenic acute regulatory protein	Rattus norvegicus	32-36
17245074-4	2007	More recent experimental and clinical studies have added data about the exact tubular sites of this insulin action, its relation with the respective insulin action on potassium handling, its possible role in the development of salt sensitivity in essential hypertension, as well as the involvement of oxidant stress in these associations.	Potassium	167-176	insulin	Homo sapiens	100-107
17245074-4	2007	More recent experimental and clinical studies have added data about the exact tubular sites of this insulin action, its relation with the respective insulin action on potassium handling, its possible role in the development of salt sensitivity in essential hypertension, as well as the involvement of oxidant stress in these associations.	Potassium	167-176	insulin	Homo sapiens	149-156
17164972-4	2007	In our study, we established the involvement of RANTES in an in vivo model of chronic inflammation induced by potassium permanganate, leading to calcified granulomas.	Potassium	110-119	C-C motif chemokine ligand 5	Rattus norvegicus	48-54
16917017-12	2007	In addition, the overall potassium loss in the BDL model is due to increased fecal potassium excretion, which is associated with upregulation of ENaC in distal colon.	Potassium	25-34	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	145-149
16917017-12	2007	In addition, the overall potassium loss in the BDL model is due to increased fecal potassium excretion, which is associated with upregulation of ENaC in distal colon.	Potassium	83-92	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	145-149
16960444-12	2007	Raising the extracellular potassium to 10 mmol/l, HERG block by azimilide, dofetilide, quinidine and sotalol was significantly decreased, while the block by amiodarone was unchanged.	Potassium	26-35	potassium voltage-gated channel subfamily H member 2	Homo sapiens	50-54
17898422-7	2007	Tobacco plants expressing activated CAX1 variants displayed hypersensitivity to ion imbalances, increased calcium accumulation, heightened concentrations of other mineral nutrients such as potassium, magnesium and manganese, and increased activity of tonoplast-enriched Ca(2+)/H(+) transport.	Potassium	189-198	cation exchanger 1	Arabidopsis thaliana	36-40
17361021-8	2007	PTP and PI3-K inhibitors showed a significantly increase in the plasma potassium concentrations not associated with EAI values.	Potassium	71-80	protein tyrosine phosphatase receptor type U	Homo sapiens	0-3
16972228-7	2007	We demonstrate that MR mutations are extremely frequent in PHA1 patients classified according to aldosterone and potassium levels and give indications for accurate clinical and biological investigation.	Potassium	113-122	nuclear receptor subfamily 3 group C member 2	Homo sapiens	20-22
16972228-7	2007	We demonstrate that MR mutations are extremely frequent in PHA1 patients classified according to aldosterone and potassium levels and give indications for accurate clinical and biological investigation.	Potassium	113-122	sodium channel epithelial 1 subunit gamma	Homo sapiens	59-63
17070838-11	2007	The change in APD90 correlated with a reduction in IK1 potassium current density in TG vs. WT cardiomyocytes (at -70 mV: 0.3+/-0.1 pA/pF vs. 0.8+/-0.2 pA/pF, P&lt;0.05).	Potassium	55-64	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	51-54
17093127-0	2007	Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.	Potassium	73-82	reciprocal translocation, Chr 16, cytogenetic band C3-4; and Chr 17, cytogenetic band A2, Davisson 65	Mus musculus	0-6
17241161-4	2007	Aggregated nitrated alpha-synuclein induced ROS production in a dose-dependent manner that was inhibited by voltage-gated potassium current blockade, and to a more limited degree, by chloride current blockade.	Potassium	122-131	synuclein, alpha	Mus musculus	20-35
17241161-5	2007	Interestingly, ROS produced in MG primed with tumor necrosis factor alpha and activated with phorbol myristate acetate was attenuated by voltage-gated potassium current blockade and more completely by chloride current blockade.	Potassium	151-160	tumor necrosis factor	Mus musculus	46-73
18283895-10	2007	In the group of 19 patients with CPK concentration of &gt;2000 U/L and myoglobin concentration of &gt;700 mcg/L crush syndrome developed in 6 (7.4%) patients with oliguria (urin output &lt;50 ml/h) and the increase of serum potassium, phosphate and creatinine concentrations.	Potassium	224-233	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	33-36
17459601-1	2007	It is proposed that insulin has a cardinal role in the regulation of serum potassium levels in man, which may be of greater importance than the effect of insulin on glucose metabolism.	Potassium	75-84	insulin	Homo sapiens	20-27
17459601-3	2007	Insulin also promotes the transport of potassium ions from the extracellular space to the intracellular space and it is suggested that there are occasions where this action may take place at the expense of glucose regulation.	Potassium	39-48	insulin	Homo sapiens	0-7
17021048-6	2007	Overexpression of GIRKs 1 and 2 in Xenopus oocytes resulted in constitutive potassium influx, corroborating the presence of basal Gbetagamma signaling in resting oocytes.	Potassium	76-85	potassium inwardly rectifying channel subfamily J member 3 L homeolog	Xenopus laevis	18-31
17095567-1	2007	Mutations within KCNE1 encoding a transmembrane protein which coassembles with K+ channels mediating slow K+, I(Ks), currents are implicated in cardiac action potential prolongation and ventricular arrhythmogenicity in long QT syndrome 5.	Potassium	112-114	potassium voltage-gated channel, Isk-related subfamily, member 1	Mus musculus	17-22
17596722-10	2007	Changes in serum potassium could be independently predicted by changes in both sNa and creatinine (R(2) = 0.11; p &lt; 0.01).	Potassium	17-26	snail family transcriptional repressor 1	Homo sapiens	79-82
17130497-5	2006	Congenic strains carrying the GK genotype distally in Niddm1i displayed reduced insulin secretion in response to both glucose and high potassium, as well as decreased single-cell exocytosis.	Potassium	135-144	Non-insulin dependent diabetes mellitus QTL 1	Rattus norvegicus	54-60
17176092-9	2006	Tryptophan quenching data indicated that transthyretin binds weakly to Abeta, with an estimated apparent KS of 2300 M-1.	Potassium	105-107	transthyretin	Mus musculus	41-54
17151284-5	2006	In response to short applications of forskolin, dopamine, or high-potassium concentration, we image an increase in cAMP levels and PKA activity, indicating that this second-messenger pathway can be activated quickly by neural activity.	Potassium	66-75	cathelicidin antimicrobial peptide	Rattus norvegicus	115-119
17151284-5	2006	In response to short applications of forskolin, dopamine, or high-potassium concentration, we image an increase in cAMP levels and PKA activity, indicating that this second-messenger pathway can be activated quickly by neural activity.	Potassium	66-75	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	131-134
18392730-1	2006	The extracellular signal-regulated kinases 1 and 2 (ERKs 1/2) are known to participate in regulating transcription in response to moderate depolarization, such as synaptic stimulation, but how the same active enzyme can differentially regulate distinct transcriptional programs induced with abnormal depolarization (high potassium) is unknown.	Potassium	321-330	mitogen-activated protein kinase 3	Homo sapiens	4-50
18392730-1	2006	The extracellular signal-regulated kinases 1 and 2 (ERKs 1/2) are known to participate in regulating transcription in response to moderate depolarization, such as synaptic stimulation, but how the same active enzyme can differentially regulate distinct transcriptional programs induced with abnormal depolarization (high potassium) is unknown.	Potassium	321-330	mitogen-activated protein kinase 3	Homo sapiens	52-60
18392730-3	2006	In support of this hypothesis, we have found that immunoreactivity for an apparent high molecular weight complex containing phospho-ERK1 increased in response to synaptic stimulation, but decreased in response to high potassium; p-ERK immunoreactivity at 44/42 kDa increased in both cases.	Potassium	218-227	mitogen-activated protein kinase 3	Homo sapiens	132-136
18392730-3	2006	In support of this hypothesis, we have found that immunoreactivity for an apparent high molecular weight complex containing phospho-ERK1 increased in response to synaptic stimulation, but decreased in response to high potassium; p-ERK immunoreactivity at 44/42 kDa increased in both cases.	Potassium	218-227	mitogen-activated protein kinase 1	Homo sapiens	132-135
17130497-6	2006	By contrast, a strain carrying the GK genotype proximally in Niddm1i exhibited both intact insulin release in response to high potassium and intact single-cell exocytosis, but insulin secretion was suppressed when stimulated by glucose.	Potassium	127-136	Non-insulin dependent diabetes mellitus QTL 1	Rattus norvegicus	61-67
17161791-0	2006	KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart.	Potassium	108-110	potassium voltage-gated channel subfamily E regulatory subunit 2	Rattus norvegicus	0-5
17161791-0	2006	KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart.	Potassium	108-110	potassium voltage-gated channel subfamily Q member 1	Rattus norvegicus	26-31
17161791-0	2006	KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart.	Potassium	108-110	potassium voltage-gated channel subfamily E regulatory subunit 1	Rattus norvegicus	36-41
17184184-7	2006	NG2(+) cells after SCI displayed altered voltage-gated potassium current profiles compared to normal adult and P7 animals.	Potassium	55-64	chondroitin sulfate proteoglycan 4	Homo sapiens	0-3
17075030-2	2006	In AS-null mice (AS(-/-)), but not in wild-type, low salt significantly decreased plasma sodium and increased potassium.	Potassium	110-119	cytochrome P450, family 11, subfamily b, polypeptide 2	Mus musculus	17-19
17010320-4	2006	EGFP-labeled cells with outwardly rectifying current-voltage relationship did not express glycine transporter 1, while GlyT1 was abundantly expressed in mature protoplasmic astrocytes, which are electrophysiologically characterized by a large potassium conductance, a more negative membrane potential and the expression of glutamate transporters.	Potassium	243-252	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	119-124
16971508-8	2006	Amiodarone, B2-O-acetate, and B2-O-Et-N-dipropyl (each 10 microM) significantly reduced the hERG tail current amplitude, whereas 10 microM B2-O-Et displayed no detectable effect on hERG outward potassium currents.	Potassium	194-203	ETS transcription factor ERG	Homo sapiens	92-96
16736206-2	2006	The apical dendrites of CA1 pyramidal neurons in hippocampus express a wide variety of sodium, calcium, potassium, and other voltage-gated channels.	Potassium	104-113	carbonic anhydrase 1	Homo sapiens	24-27
17022037-3	2006	Cortical neurons exposed to Abeta(1-40) 5 muM developed a specific increase in the delayed rectifier potassium current (I(K)), but not the transient outward potassium currents (I(A)), before the appearance of neuronal apoptosis.	Potassium	101-110	amyloid beta precursor protein	Rattus norvegicus	28-33
16928787-3	2006	When stably expressed in HEK293 cells, rMATE1 could mediate the transport of tetraethylammonium (TEA) and cimetidine under the condition where the membrane potential was disrupted by a high concentration of potassium ion and intracellular pH was reduced by NH(4)Cl pretreatment.	Potassium	207-216	solute carrier family 47 member 1	Rattus norvegicus	39-45
17185507-11	2006	Thus, N-acetylglucosamine 6-O-sulfotransferase-1 plays indispensable roles in brain KS biosynthesis and glial scar formation after brain injury.	Potassium	84-86	carbohydrate sulfotransferase 1	Mus musculus	6-48
17125532-6	2006	A high intake of calcium, magnesium and potassium, together with a low sodium intake, is associated with protection against bone demineralisation, arterial hypertension, insulin resistance, and overall cardiovascular risk.	Potassium	40-49	insulin	Homo sapiens	170-177
16982042-2	2006	Through the measurements of lysosomal beta-hexosaminidase free activity, their membrane potential, the intra-lysosomal pH and the lysosomal latency loss in hypotonic sucrose medium, we established that PLA(2) could increase the lysosomal membrane permeability to both potassium ions and protons.	Potassium	268-277	phospholipase A2 group IIA	Homo sapiens	202-207
16954157-11	2006	In addition, GIP reduced the amplitude of transient and sustained potassium currents in H2.	Potassium	66-75	gastric inhibitory polypeptide	Homo sapiens	13-16
16916995-0	2006	Properties of a time-dependent potassium current in pig atrium: evidence for a role of kv1.5 in repolarization.	Potassium	31-40	KV1.5	Sus scrofa	87-92
16973276-2	2006	Extracellular signal-regulated kinases (ERK1/2) are thought to be activated in response to potassium depolarization and responsible for the activity-dependent survival in CGNs, but one recent study has revealed that ERK1/2 is activated by potassium deprivation and is required for apoptosis of CGNs.	Potassium	91-100	mitogen-activated protein kinase 3	Homo sapiens	40-46
16928897-11	2006	During a voltage-clamp protocol using prerecorded cardiac action potentials, 2.5 microM MTX increased the total potassium ions passed through hERG channels by approximately 5-fold.	Potassium	112-121	ETS transcription factor ERG	Homo sapiens	142-146
16956952-10	2006	We also show that KS lesions, in vivo, express elevated levels of HIF1alpha and HIF2alpha proteins.	Potassium	18-20	hypoxia inducible factor 1 subunit alpha	Homo sapiens	66-75
16956952-10	2006	We also show that KS lesions, in vivo, express elevated levels of HIF1alpha and HIF2alpha proteins.	Potassium	18-20	endothelial PAS domain protein 1	Homo sapiens	80-89
17283546-0	2006	[Mice lacking the marginal cell KCNQ1 have impaired cochlear potassium cycling are profoundly deaf].	Potassium	61-70	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	32-37
16973276-2	2006	Extracellular signal-regulated kinases (ERK1/2) are thought to be activated in response to potassium depolarization and responsible for the activity-dependent survival in CGNs, but one recent study has revealed that ERK1/2 is activated by potassium deprivation and is required for apoptosis of CGNs.	Potassium	91-100	mitogen-activated protein kinase 3	Homo sapiens	216-222
16973276-2	2006	Extracellular signal-regulated kinases (ERK1/2) are thought to be activated in response to potassium depolarization and responsible for the activity-dependent survival in CGNs, but one recent study has revealed that ERK1/2 is activated by potassium deprivation and is required for apoptosis of CGNs.	Potassium	239-248	mitogen-activated protein kinase 3	Homo sapiens	40-46
16973276-2	2006	Extracellular signal-regulated kinases (ERK1/2) are thought to be activated in response to potassium depolarization and responsible for the activity-dependent survival in CGNs, but one recent study has revealed that ERK1/2 is activated by potassium deprivation and is required for apoptosis of CGNs.	Potassium	239-248	mitogen-activated protein kinase 3	Homo sapiens	216-222
16973276-3	2006	In this study we showed that ERK1/2 was inactivated, rather than activated, by potassium deprivation, indicating a lack of ERK1/2 involvement in potassium deprivation-induced apoptosis.	Potassium	79-88	mitogen-activated protein kinase 3	Homo sapiens	29-35
16973276-4	2006	Furthermore, suppression of potassium depolarization-induced activation of ERK1/2 with chemical inhibitor U0126 or PD98059 had no influence on the pro-survival effect of potassium depolarisation.	Potassium	28-37	mitogen-activated protein kinase 3	Homo sapiens	75-81
16901946-5	2006	In hippocampal pyramidal neurones we studied the modulation of a potassium current (slow AHP current, I(sAHP)) known to be targeted by multiple transmitter systems that use cAMP-PKA.	Potassium	65-74	cathelicidin antimicrobial peptide	Rattus norvegicus	173-177
17029381-3	2006	The X-ray crystal structures of these new complexes were determined, and the solid-state structures consist of the nitrogen heterocycles bonded to the (18-crown-6)potassium cationic fragments with eta2-bonding interactions.	Potassium	163-172	DNA polymerase iota	Homo sapiens	197-201
16911838-14	2006	Whole cell outward currents, mainly carried by potassium ions, were reduced by 2,4-DBP with a half-maximal concentration of 41+/-9 microM (S.D.)	Potassium	47-56	D-box binding PAR bZIP transcription factor	Rattus norvegicus	83-86
16945513-6	2006	This result suggests that KS in the IGD may compete with CS for ADAMTS-4 (p68) binding.	Potassium	26-28	A disintegrin and metalloproteinase with thrombospondin motifs 4	Cricetulus griseus	64-72
17469342-8	2006	The glucose-insulin-potassium solution provides the glucose needed by the myocardium in reperfusion conditions and protects the cellular membrane"s integrity as well as pumps and ionic channels, it allows maintaining the action potential probably because ATP-depended channels block and prevent potassium loss, it reduces the cytosol calcium overload and prevent cardiac arrhythmias, preserves the sodium ATPasa pump avoiding the rise in cytosolic sodium; glucose prevents the production of free oxygen radicals.	Potassium	20-29	insulin	Homo sapiens	12-19
16943722-2	2006	Several further trials and meta-analyses investigating the role of insulin treatment, either aimed at tight control of blood glucose concentration or as part of a regimen including glucose and potassium, have been reported recently and are the subject of this review.	Potassium	193-202	insulin	Homo sapiens	67-74
16943722-5	2006	The use of glucose-insulin-potassium regimens does not improve outcomes in patients with acute myocardial infarction who have undergone reperfusion therapy, but may be beneficial during cardiac surgery.	Potassium	27-36	insulin	Homo sapiens	19-26
16966485-7	2006	Potassium-induced depolarization activated PDYN processing and secretion of opioid peptides in neuronal cultures and in a model cell line.	Potassium	0-9	prodynorphin	Homo sapiens	43-47
16820361-1	2006	The Kv4.2 transient voltage-dependent potassium current contributes to the morphology of the cardiac action potential as well as to neuronal excitability and firing frequency.	Potassium	38-47	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	4-9
16964266-0	2006	Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule.	Potassium	33-42	WNK lysine deficient protein kinase 4	Mus musculus	0-4
16838364-3	2006	A recent electrophysiological study on GP slices described NT-mediated robust membrane depolarization, depending upon the suppression of potassium conductance and/or the activation of cation current.	Potassium	137-146	neurotensin	Rattus norvegicus	59-61
16990137-3	2006	Here we show that toxin-induced membrane permeabilization leads to a decrease in cytoplasmic potassium, which promotes the formation of a multiprotein oligomeric innate immune complex, called the inflammasome, and the activation of caspase-1.	Potassium	93-102	caspase 1	Homo sapiens	232-241
16876110-6	2006	Real-time RT-PCR showed that the expression of CYP11B2 mRNA in mesangial cells was significantly enhanced by AngII (P&lt;0.001) and by potassium (P&lt;0.05).	Potassium	135-144	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	47-54
16825309-7	2006	LIL-6 males and IL-6 females showed decreased urinary flow rate and urinary sodium and potassium excretion.	Potassium	87-96	Serum phospholipid level QTL 2	Rattus norvegicus	0-5
16707771-7	2006	The absolute maximum responses to NKA and its stable NK2 receptor-selective analogue, [Lys5MeLeu9Nle10]NKA(4-10), were increased in pregnancy, but their efficacies relative to potassium responses were decreased.	Potassium	176-185	tachykinin precursor 1	Homo sapiens	34-37
16825309-7	2006	LIL-6 males and IL-6 females showed decreased urinary flow rate and urinary sodium and potassium excretion.	Potassium	87-96	interleukin 6	Rattus norvegicus	1-5
16831872-4	2006	We found that overexpression of mir-9 in insulin-secreting cells causes a reduction in exocytosis elicited by glucose or potassium.	Potassium	121-130	insulin	Homo sapiens	41-48
16914958-8	2006	The elimination of rigid limitations to increases in serum potassium and serum creatinine is suggested as a means to enhance prescription of renin-angiotensin system inhibitors.	Potassium	59-68	renin	Homo sapiens	141-146
16838374-4	2006	We observed that in these cultured cells, calcium transients induced by extracellular potassium were significantly reduced by a reduction-of-function mutation in egl-19 and significantly reduced by L-type calcium channel inhibitors; thus, a main source of touch neuron calcium transients appeared to be influx of extracellular calcium through L-type channels.	Potassium	86-95	Voltage-dependent L-type calcium channel subunit alpha	Caenorhabditis elegans	162-168
16960425-3	2006	We reviewed the role of NCX in cardiac triggered activity in limited experimental conditions: the digitalis-induced arrhythmia, the arrhythmia caused from sustained opening of sodium channel, and the arrhythmia caused from the inhibition of inwardly rectifying potassium current.	Potassium	261-270	T cell leukemia homeobox 2	Homo sapiens	24-27
16713607-12	2006	The excitatory actions of orexin-B result from a decrease in the apparent leak potassium current (Kleak).	Potassium	79-88	hypocretin neuropeptide precursor	Homo sapiens	26-32
16802333-6	2006	Mu-opioid receptor (MOPR) agonists induced postsynaptic inhibitory potassium currents in 61% of CeA cells, and this ratio was maintained in each subdivision and for each physiological class of neuron.	Potassium	67-76	carcinoembryonic antigen gene family 4	Rattus norvegicus	96-99
17111813-1	2006	OBJECTIVE: To investigate the auditory function and the role of NKCC1 and alpha2 Na, K-ATPase in the potassium recycling of cochlea.	Potassium	101-110	solute carrier family 12, member 2	Mus musculus	64-69
17111813-6	2006	The auditory function of NKCC1(+/-) / alpha2 Na, K-ATPase(+/-) mice could simulate the model of cochlear potassium recycling well.	Potassium	105-114	solute carrier family 12, member 2	Mus musculus	25-30
17111813-7	2006	NKCC1 and Na, K-ATPase were great of importance in the potassium recycling, while the two ion channels were in restrict dynamic equilibrium.	Potassium	55-64	solute carrier family 12, member 2	Mus musculus	0-5
17111813-11	2006	CONCLUSIONS: Ion channel NKCC1 and alpha2 Na, K-ATPase played important roles in the inner ear potassium recycling.	Potassium	95-104	solute carrier family 12, member 2	Mus musculus	25-30
17111813-13	2006	The role of NKCC1 and alpha2 Na, K-ATPase in cochlear potassium recycling was authenticated in vivo.	Potassium	54-63	solute carrier family 12, member 2	Mus musculus	12-17
16751194-6	2006	PKC sequestration and pericentrion formation were blocked by hypertonic sucrose as well as by potassium depletion (inhibitors of clathrin-dependent endocytosis) but not by nystatin or filipin, which inhibit clathrin-independent pathways.	Potassium	94-103	proline rich transmembrane protein 2	Homo sapiens	0-3
16885549-1	2006	BACKGROUND: The ATP-sensitive potassium (K(ATP)) channel, composed of the beta-cell proteins sulfonylurea receptor (SUR1) and inward-rectifying potassium channel subunit Kir6.2, is a key regulator of insulin release.	Potassium	30-39	ATP binding cassette subfamily C member 8	Homo sapiens	116-120
16782062-2	2006	Kv4.3 is the major component of various physiologically important currents ranging from A-type currents in the CNS to the transient outward potassium conductance in the heart (I(to)).	Potassium	140-149	potassium voltage-gated channel subfamily D member 3	Homo sapiens	0-5
16885549-1	2006	BACKGROUND: The ATP-sensitive potassium (K(ATP)) channel, composed of the beta-cell proteins sulfonylurea receptor (SUR1) and inward-rectifying potassium channel subunit Kir6.2, is a key regulator of insulin release.	Potassium	30-39	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	170-176
16885550-1	2006	BACKGROUND: Heterozygous activating mutations in KCNJ11, encoding the Kir6.2 subunit of the ATP-sensitive potassium (K(ATP)) channel, cause 30 to 58 percent of cases of diabetes diagnosed in patients under six months of age.	Potassium	106-115	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	49-55
16885550-1	2006	BACKGROUND: Heterozygous activating mutations in KCNJ11, encoding the Kir6.2 subunit of the ATP-sensitive potassium (K(ATP)) channel, cause 30 to 58 percent of cases of diabetes diagnosed in patients under six months of age.	Potassium	106-115	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	70-76
16729967-0	2006	Extracellular potassium deprivation reversibly dephosphorylates cofilin.	Potassium	14-23	cofilin 1	Homo sapiens	64-71
17111037-7	2006	PC2 and its homologue, polycystin-L (PCL), are nonselective cation channels permeable to potassium, sodium, and calcium.	Potassium	89-98	polycystin 2, transient receptor potential cation channel	Homo sapiens	0-3
17111037-7	2006	PC2 and its homologue, polycystin-L (PCL), are nonselective cation channels permeable to potassium, sodium, and calcium.	Potassium	89-98	polycystin 2 like 1, transient receptor potential cation channel	Homo sapiens	23-35
17111037-7	2006	PC2 and its homologue, polycystin-L (PCL), are nonselective cation channels permeable to potassium, sodium, and calcium.	Potassium	89-98	polycystin 2 like 1, transient receptor potential cation channel	Homo sapiens	37-40
16707716-0	2006	Nerve growth factor decreases potassium currents and alters repetitive firing in rat sympathetic neurons.	Potassium	30-39	nerve growth factor	Rattus norvegicus	0-19
16707716-7	2006	NGF causes a decrease in the amplitude of both calcium-dependent and -independent potassium currents, and inhibition of calcium-dependent potassium currents using CdCl(2) reproduces some, but not all, of the firing properties induced by NGF.	Potassium	82-91	nerve growth factor	Rattus norvegicus	0-3
16707716-7	2006	NGF causes a decrease in the amplitude of both calcium-dependent and -independent potassium currents, and inhibition of calcium-dependent potassium currents using CdCl(2) reproduces some, but not all, of the firing properties induced by NGF.	Potassium	138-147	nerve growth factor	Rattus norvegicus	237-240
16820787-4	2006	In this mini review, we discuss WNK1 and WNK4 gene products and their regulatory effects on sodium chloride and potassium handling in the aldosterone-sensitive distal nephron.	Potassium	112-121	WNK lysine deficient protein kinase 1	Homo sapiens	32-36
16820787-4	2006	In this mini review, we discuss WNK1 and WNK4 gene products and their regulatory effects on sodium chloride and potassium handling in the aldosterone-sensitive distal nephron.	Potassium	112-121	WNK lysine deficient protein kinase 4	Homo sapiens	41-45
16863288-6	2006	S1 accommodates Ks with attributes above tao 1 &lt; or = tao 0.	Potassium	16-18	TAO kinase 1	Homo sapiens	41-46
16735023-3	2006	Here, we report that the induction of apoptosis by withdrawal of serum and potassium triggers dephosphorylation of GSK-3beta at serine 9 and subsequent translocation of these molecules into neuronal lipid raft microdomains.	Potassium	75-84	glycogen synthase kinase 3 beta	Homo sapiens	115-124
16797382-6	2006	Combination therapy with an ACE inhibitor and an ARB resulted in a small, but significant, increase in serum potassium levels (weighted mean difference, 0.11 mEq/L [0.11 mmol/L]; 95% confidence interval [CI], 0.05 to 0.17) and a nonsignificant decrease in glomerular filtration rate (weighted mean difference, 1.4 mL/min [0.02 mL/s]; 95% CI, -2.6 to 0.2).	Potassium	109-118	angiotensin I converting enzyme	Homo sapiens	28-31
16481373-0	2006	Cytosolic potassium controls CFTR deactivation in human sweat duct.	Potassium	10-19	CF transmembrane conductance regulator	Homo sapiens	29-33
16571596-0	2006	Mice heterozygous for beta-ENaC deletion have defective potassium excretion.	Potassium	56-65	sodium channel, nonvoltage-gated 1 beta	Mus musculus	22-31
16905514-4	2006	In 2 prospective studies using glucose-insulin-potassium infusion, glucose levels did not reach target, and the results of both trials were negative with regard to the primary endpoint, mortality.	Potassium	47-56	insulin	Homo sapiens	39-46
16818216-8	2006	Upon further investigation, we found that cycle length instability during HCN expression was primarily due to a gradual reduction of intracellular potassium ([K(+)](i)) from its baseline value of 142 mM to 120 mM in 600 beats and subsequent alteration of potassium-dependent ionic currents.	Potassium	147-156	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	74-77
16647783-5	2006	Yotiao forms a macromolecular complex with the channel and recruits key enzymes such as PKA and protein phosphatase 1 (PP1) to control the phosphorylation state of I(Ks).	Potassium	166-168	A-kinase anchoring protein 9	Homo sapiens	0-6
16647783-5	2006	Yotiao forms a macromolecular complex with the channel and recruits key enzymes such as PKA and protein phosphatase 1 (PP1) to control the phosphorylation state of I(Ks).	Potassium	166-168	neuropeptide Y receptor Y4	Homo sapiens	96-117
16647783-5	2006	Yotiao forms a macromolecular complex with the channel and recruits key enzymes such as PKA and protein phosphatase 1 (PP1) to control the phosphorylation state of I(Ks).	Potassium	166-168	neuropeptide Y receptor Y4	Homo sapiens	119-122
16647783-6	2006	Our recent findings revealed a more active role of Yotiao in the PKA modulation of I(Ks).	Potassium	85-87	A-kinase anchoring protein 9	Homo sapiens	51-57
16647783-10	2006	Taken together we have evidence to suggest that Yotiao plays dual roles in the PKA modulation of the I(Ks) channel.	Potassium	103-105	A-kinase anchoring protein 9	Homo sapiens	48-54
16818216-8	2006	Upon further investigation, we found that cycle length instability during HCN expression was primarily due to a gradual reduction of intracellular potassium ([K(+)](i)) from its baseline value of 142 mM to 120 mM in 600 beats and subsequent alteration of potassium-dependent ionic currents.	Potassium	255-264	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	74-77
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	224-233	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	124-130
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	224-233	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	132-137
16710355-0	2006	Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter"s syndrome and in adaptation to a high-K diet.	Potassium	38-47	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	65-69
16710355-2	2006	Newborns with Type II Bartter are transiently hyperkalemic, consistent with loss of ROMK channel function in potassium secretion in distal convoluted tubule and CCT.	Potassium	109-118	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	84-88
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	150-159	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	110-114
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	150-159	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	124-130
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	150-159	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	132-137
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	150-159	talipes	Mus musculus	215-218
16710355-8	2006	Thus, renal potassium wasting in Type II Bartter is due to both reduced reabsorption in the TAL and K secretion by max-K channels in the late distal tubule.	Potassium	12-21	talipes	Mus musculus	92-95
16773405-5	2006	During the first days after birth, higher urinary AQP2 was observed in boys than in girls (P=0.01) and positively correlated with urinary sodium/potassium (Na/K) ratio (r=0.33, P=0.01).	Potassium	145-154	aquaporin 2	Homo sapiens	50-54
16710355-1	2006	Type II Bartter"s syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium recycling in the thick ascending limb of Henle"s loop (TAL) and potassium secretion in the distal tubule and cortical collecting duct (CCT).	Potassium	224-233	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	110-114
16674922-3	2006	Here we show for the first time that Zn(2+)-induced aggregation of Abeta (10-21) potentiates its action on outward potassium currents in hippocampal CA1 pyramidal neurons.	Potassium	115-124	carbonic anhydrase 1	Homo sapiens	149-152
16765055-6	2006	In contrast, CGN apoptosis elicited by TFW (i.e., removal of serum and depolarizing extracellular potassium) did not display any ER stress component nor was it blocked by either 2-APB or ER-Bcl-2.	Potassium	98-107	cingulin	Rattus norvegicus	13-16
16734443-1	2006	Reduction of the new, naphthalene-based pincer complex [(C10H5(CH2PiPr2)2)Rh(eta1-N2)] with potassium metal gave the corresponding sigma-coordinated naphthyl radical anion complex, with a ring-centered radical and no change in the formal metal oxidation state.	Potassium	92-107	secreted phosphoprotein 1	Homo sapiens	77-81
17083062-7	2006	CNP relaxation was also inhibited by high potassium or iberiotoxin, indicating that it was due to opening of BKCa channels.	Potassium	42-51	natriuretic peptide C	Homo sapiens	0-3
16551834-6	2006	Extracellular high potassium (80 mM), which inactivates the potassium channels, reduced the adrenomedullin-induced relaxation.	Potassium	19-28	adrenomedullin	Rattus norvegicus	92-106
17042092-4	2006	RESULTS: Within the arrange of 0-180 kg K2SO4/hm2, the content of chlorophyll and amino acid, Fv/Fo, Fv/Fm, and phiPs II were increased with the increase in potassium level.	Potassium	157-166	cholinergic receptor muscarinic 2	Homo sapiens	46-49
17042092-7	2006	CONCLUSION: It indicats that higher yield and diosgenin content can be obtained when the potassium level is 180 kg K2/hm2.	Potassium	89-98	cholinergic receptor muscarinic 2	Homo sapiens	118-121
16608704-8	2006	In this paper, our emphasis is on the two highly nonlinear inwardly rectifying potassium currents, (IK1) and (IK,r).	Potassium	79-88	IKAROS family zinc finger 1	Homo sapiens	100-103
16709664-0	2006	WNK1 kinase isoform switch regulates renal potassium excretion.	Potassium	43-52	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	0-4
16709664-2	2006	Gain-of-expression mutations in the WNK1 gene uncouple Na(+) and K(+) balance and cause a familial disorder of diminished renal potassium excretion, excessive sodium retention, and hypertension (pseudohypoaldosteronism type II or Gordon"s syndrome).	Potassium	128-137	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	36-40
16709664-3	2006	Alternative splicing of the WNK1 gene produces a kidney-specific short form of WNK1 (KS-WNK1) and a more ubiquitous long form (L-WNK1), but it is not clear how either of these isoforms influence renal potassium excretion.	Potassium	201-210	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	28-32
16709664-9	2006	Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition.	Potassium	14-23	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	68-75
16709664-9	2006	Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition.	Potassium	14-23	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	71-75
16709664-9	2006	Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition.	Potassium	14-23	potassium inwardly rectifying channel subfamily J member 1 L homeolog	Xenopus laevis	169-175
16709664-9	2006	Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition.	Potassium	14-23	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	81-85
16709664-9	2006	Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition.	Potassium	14-23	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	220-227
16709664-9	2006	Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition.	Potassium	14-23	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	81-85
16527853-9	2006	The activation curve shifted to more positive potentials as [K+]o was reduced, so that the pharmacological and biophysical properties of I(Ks) were consistent with those of heterologously expressed homomeric KCNQ2 channels.	Potassium	139-141	potassium voltage-gated channel subfamily Q member 2	Rattus norvegicus	208-213
16706845-0	2006	Oxidative modulation of the transient potassium current IA by intracellular arachidonic acid in rat CA1 pyramidal neurons.	Potassium	38-47	carbonic anhydrase 1	Rattus norvegicus	100-103
16531080-1	2006	We have recently shown that amino acid substitutions in the membrane domain of band 3 (anion exchanger 1, SLC4A1) are associated with hereditary stomatocytosis (HSt), a red cell condition in which the cells leak sodium and potassium ions.	Potassium	223-232	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	106-112
16641887-5	2006	This may have relevance to the use of glucose-insulin-potassium regimen in these clinical conditions, sepsis, and cancer.	Potassium	54-63	insulin	Homo sapiens	46-53
16555239-5	2006	We also found that depolarization induced by high potassium levels elicits a slow, partial exocytotic release of tPA from DCGs in spines that is dependent on extracellular Ca(+2) concentrations.	Potassium	50-59	plasminogen activator, tissue type	Homo sapiens	113-116
16624558-6	2006	This shows that the Val1589Met mutation in the SCN4 gene may cause different phenotypes, either potassium-aggravated myotonia or paramyotonia congenita.	Potassium	96-105	glucose-6-phosphatase catalytic subunit 3	Homo sapiens	47-51
16734088-8	2006	Time from admission to initiation of subcutaneous insulin therapy was correlated with lower serum potassium concentration (P = .0056), lower serum phosphorus concentration (P = .0043), abnormally high white blood cell count (P = .0060), large base deficit (P = .0015), and low venous pH (P &lt; .001).	Potassium	98-107	insulin	Canis lupus familiaris	50-57
16848292-1	2006	OBJECTIVE: To explore the dependence of Ca2+ on the acetylcholine (ACh)-sensitive potassium current in guinea pig type II vestibular hair cells.	Potassium	82-91	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	40-43
16713495-2	2006	Patients with hereditary NDI bearing mutations in AVPR2, the gene coding for the arginine vasopressin 2 receptor, or in AQP2, the gene coding for the vasopressin-sensitive water channel, have a pure NDI phenotype with loss of water, but normal conservation of sodium, potassium, chloride, and calcium.	Potassium	268-277	aquaporin 2	Homo sapiens	120-124
16848292-2	2006	METHODS: Under the whole-cell patch mode, the current amplitude of the ACh-sensitive potassium current was recorded in response to the concentration change of the extracellular or intracellular Ca2+.	Potassium	85-94	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	194-197
16848292-4	2006	The activation of the ACh-sensitive potassium current was strongly affected by the concentration of the extracellular Ca2+.	Potassium	36-45	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	118-121
16641240-2	2006	Purkinje neurons express two ionic currents with biophysical properties that are specialized for high-frequency firing: resurgent sodium currents and potassium currents mediated by Kv3.3.	Potassium	150-159	potassium voltage gated channel, Shaw-related subfamily, member 3	Mus musculus	181-186
16848292-5	2006	The current amplitude of the ACh-sensitive potassium increased following the increase of Ca2+ concentration from 0 mmol/L to 4 mmol/L At the concentration of 4 mmol/L Ca2+, the current amplitude of the ACh-sensitive potassium current reached the maximal response.	Potassium	43-52	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	89-92
16848292-5	2006	The current amplitude of the ACh-sensitive potassium increased following the increase of Ca2+ concentration from 0 mmol/L to 4 mmol/L At the concentration of 4 mmol/L Ca2+, the current amplitude of the ACh-sensitive potassium current reached the maximal response.	Potassium	43-52	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	167-170
16848292-10	2006	CONCLUSIONS: The activation of the ACh-sensitive potassium current in guinea pig type II vestibular hair cells was dependent on the extracellular Ca2+ influx through the calcium channel.	Potassium	49-58	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	146-149
16848292-11	2006	The application of ACh would stimulate membrane Ca2+ channels; the influx of Ca2+ will then activate the calcium-dependent potassium current in guinea pig type II hair cells to mediate the hyperpolarization effect.	Potassium	123-132	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	77-80
16641240-7	2006	We conclude that the rate of spontaneous action potential firing of Purkinje neurons is controlled by the interaction of Kv3.3 potassium currents and resurgent sodium currents.	Potassium	127-136	potassium voltage gated channel, Shaw-related subfamily, member 3	Mus musculus	121-126
16470808-0	2006	Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels.	Potassium	38-47	aquaporin 4	Mus musculus	73-84
16470808-1	2006	The glial water channel aquaporin-4 (AQP4) has been hypothesized to modulate water and potassium fluxes associated with neuronal activity.	Potassium	87-96	aquaporin 4	Mus musculus	24-35
16470808-1	2006	The glial water channel aquaporin-4 (AQP4) has been hypothesized to modulate water and potassium fluxes associated with neuronal activity.	Potassium	87-96	aquaporin 4	Mus musculus	37-41
16470808-7	2006	These results implicate AQP4 in the expression and termination of seizure activity and support the hypothesis that AQP4 is coupled to potassium homeostasis in vivo.	Potassium	134-143	aquaporin 4	Mus musculus	115-119
16273079-1	2006	Apoptosis in cortical neurons requires efflux of cytoplasmic potassium mediated by a surge in Kv2.1 channel activity.	Potassium	61-70	potassium voltage-gated channel subfamily B member 1	Homo sapiens	94-99
16602804-4	2006	Each potassium in 2 is ligated by an eta4-toluene, two bridging nitrogen atoms, and an eta2-phenyl, an eta1-phenyl, and an eta1-methyl group.	Potassium	5-14	DNA polymerase iota	Homo sapiens	87-91
16602804-4	2006	Each potassium in 2 is ligated by an eta4-toluene, two bridging nitrogen atoms, and an eta2-phenyl, an eta1-phenyl, and an eta1-methyl group.	Potassium	5-14	secreted phosphoprotein 1	Homo sapiens	103-107
16602804-4	2006	Each potassium in 2 is ligated by an eta4-toluene, two bridging nitrogen atoms, and an eta2-phenyl, an eta1-phenyl, and an eta1-methyl group.	Potassium	5-14	secreted phosphoprotein 1	Homo sapiens	123-127
16344329-6	2006	TREK-1 may modulate potassium current of glomus cells and/or afferent nerve endings in the rat carotid body.	Potassium	20-29	potassium two pore domain channel subfamily K member 2	Rattus norvegicus	0-6
16402204-6	2006	The capacity of the Nha1 antiporter to transport potassium is regulated by Hog1 kinase.	Potassium	49-58	Nha1p	Saccharomyces cerevisiae S288C	20-24
16402204-6	2006	The capacity of the Nha1 antiporter to transport potassium is regulated by Hog1 kinase.	Potassium	49-58	mitogen-activated protein kinase HOG1	Saccharomyces cerevisiae S288C	75-79
16402204-8	2006	The C-terminal-less Nha1 version is not inactivated and its potassium efflux activity renders cells very sensitive to hyperosmotic shock.	Potassium	60-69	Nha1p	Saccharomyces cerevisiae S288C	20-24
16909339-1	2006	The present study was designed to characterize pharmacological, biophysical and electrophysiological properties of the recombinant human cardiac I (Ks) (KCNQ1/KCNE1) channels at physiological temperature.	Potassium	148-150	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	153-158
16524946-0	2006	Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion.	Potassium	165-174	solute carrier family 26 member 7	Homo sapiens	31-38
16524946-9	2006	In separate studies, SLC26A7 showed predominant localization in plasma membrane in potassium-depleted isotonic medium (0.5 or 2 mEq/L KCl) versus cytoplasmic distribution in normal potassium isotonic medium (4 mEq/L).	Potassium	83-92	solute carrier family 26 member 7	Homo sapiens	21-28
16524946-9	2006	In separate studies, SLC26A7 showed predominant localization in plasma membrane in potassium-depleted isotonic medium (0.5 or 2 mEq/L KCl) versus cytoplasmic distribution in normal potassium isotonic medium (4 mEq/L).	Potassium	181-190	solute carrier family 26 member 7	Homo sapiens	21-28
16524946-10	2006	It is concluded that SLC26A7 is present in endosomes, and its targeting to the basolateral membrane is increased in hypertonicity and potassium depletion.	Potassium	134-143	solute carrier family 26 member 7	Homo sapiens	21-28
16909339-1	2006	The present study was designed to characterize pharmacological, biophysical and electrophysiological properties of the recombinant human cardiac I (Ks) (KCNQ1/KCNE1) channels at physiological temperature.	Potassium	148-150	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	159-164
16909339-4	2006	The typical I (Ks) was slowly activated upon depolarization voltages in HEK 293 cells stably expressing human cardiac KCNQ1 and KCNE1 genes, and the current was inhibited by I (Ks) blockers HMR 1556 and chromanol 293B, with 50% inhibitory concentrations (IC(50)s) of 83.8 nM: and 9.2 muM: , respectively.	Potassium	15-17	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	118-123
16909339-4	2006	The typical I (Ks) was slowly activated upon depolarization voltages in HEK 293 cells stably expressing human cardiac KCNQ1 and KCNE1 genes, and the current was inhibited by I (Ks) blockers HMR 1556 and chromanol 293B, with 50% inhibitory concentrations (IC(50)s) of 83.8 nM: and 9.2 muM: , respectively.	Potassium	15-17	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	128-133
16413055-9	2006	Capsaicin, bradykinin and the potassium solution caused concentration-dependent increases in CGRP release.	Potassium	30-39	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	93-97
16516892-4	2006	Treatment by the neurotrophin, NT-3, significantly attenuated the decline of NDAP in neurons from days 2 to 10, whereas growth factors such as GDNF and insulin, and high potassium levels did not.	Potassium	170-179	3'-nucleotidase	Homo sapiens	31-35
16518493-1	2006	Crystallization studies of C-methyl pyrogallarene with potassium, rubidium and caesium bromides or chlorides resulted in a hydrogen bonded molecular cage in which the alkali metal cations are eta6 coordinated to aromatic rings via strong cation-pi interactions.	Potassium	55-64	endothelin receptor type A	Homo sapiens	175-178
16303259-8	2006	The sodium and potassium transport activity of Nha1 antiporters from both D. hansenii strains was almost identical, indicating that plasma membrane antiporter activity is not one of the factors determining the different levels of halotolerance in the two strains.	Potassium	15-24	Nha1p	Saccharomyces cerevisiae S288C	47-51
16380382-0	2006	N-methyl-D-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells.	Potassium	93-102	mitogen-activated protein kinase 8	Homo sapiens	42-45
16566422-7	2006	Patients starting treatment with cholinesterase inhibitors should be screened for an increased risk of cardiac arrhythmias by investigating their potassium concentrations and running an ECG.	Potassium	146-155	butyrylcholinesterase	Homo sapiens	33-47
16532212-6	2006	This review discusses the effect of both rare and polymorphic alleles in the human phenotype, showing that deficiency of one of the collagen XVIII isoforms is sufficient to cause KS and that null alleles causing deficiency of all collagen XVIII isoforms are associated with a more severe ocular defect.	Potassium	179-181	collagen type XVIII alpha 1 chain	Homo sapiens	132-146
16204408-5	2006	Na+ transport studies in Xenopus laevis oocytes demonstrate that KS-WNK1 downregulates NCC activity indirectly, by inhibiting L-WNK1.	Potassium	65-67	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	68-72
16204408-5	2006	Na+ transport studies in Xenopus laevis oocytes demonstrate that KS-WNK1 downregulates NCC activity indirectly, by inhibiting L-WNK1.	Potassium	65-67	WNK lysine deficient protein kinase 1 L homeolog	Xenopus laevis	126-132
16463373-8	2006	Interestingly, Kcne3 expression is also widely observed in distinct tissue layers during embryogenesis, supporting the notion that an exquisite balance of alpha- and beta-subunit expression is required for modulating potassium conductance in distinct organs and tissue layers.	Potassium	217-226	potassium voltage-gated channel, Isk-related subfamily, gene 3	Mus musculus	15-20
16450155-8	2006	The additional potassium excretion induced by 100 mg HCT was 44+/-21, 33+/-27 and 16+/-26 mmol (mean+/-SD, p&lt;0.001) in ACE II, ID and DD carriers and the same trend was observed after 25 mg HCT.	Potassium	15-24	angiotensin I converting enzyme	Homo sapiens	122-125
16503757-6	2006	This raises the possibility that cardiac-specific antagonists of the MR may be developed that avoid the potassium retention seen with blockade of the renal MR.	Potassium	104-113	nuclear receptor subfamily 3 group C member 2	Homo sapiens	69-71
25696601-0	2006	Glucose and potassium derangements by glucose-insulin-potassium infusion in acute myocardial infarction.	Potassium	12-21	insulin	Homo sapiens	46-53
16250016-5	2006	Furthermore, whole cell patch clamp electrophysiology demonstrates that these cells express a spontaneously active, outwardly rectifying potassium "background leak" current that shares many similarities to TREK-1.	Potassium	137-146	potassium two pore domain channel subfamily K member 2	Homo sapiens	206-212
25696601-0	2006	Glucose and potassium derangements by glucose-insulin-potassium infusion in acute myocardial infarction.	Potassium	54-63	insulin	Homo sapiens	46-53
25696601-1	2006	BACKGROUND: High-dose glucose-insulin-potassium infusion (GIK) has been suggested to be beneficial in acute myocardial infarction (MI).	Potassium	38-47	insulin	Homo sapiens	30-37
16208521-9	2006	In conclusion, types I and III K-ATPases measured in collecting ducts of normal and potassium-depleted mice reflect the functional expression of gastric and colonic H,K-ATPase, respectively.	Potassium	84-93	ATPase, H+/K+ exchanging, beta polypeptide	Mus musculus	165-175
16480714-5	2006	A concentration-dependent effect of estradiol on the KCNQ1/KCNE1-mediated potassium current was observed.	Potassium	74-83	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	53-58
16293366-4	2006	A high concentration of potassium ions (K(+), 100 mM) was used to ascertain the neuronal release of somatostatin.	Potassium	24-33	somatostatin	Rattus norvegicus	100-112
16480714-5	2006	A concentration-dependent effect of estradiol on the KCNQ1/KCNE1-mediated potassium current was observed.	Potassium	74-83	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	59-64
16480714-7	2006	The HERG-mediated potassium and the SCN5A-mediated sodium currents, however, were only slightly reduced by estradiol at concentrations of up to 30 microM.	Potassium	18-27	potassium voltage-gated channel subfamily H member 2	Homo sapiens	4-8
16192299-9	2006	However, further isolation of background currents by recording in solutions that contained only sodium or only potassium revealed that both leptin and CCK were capable of increasing a sodium-dependent conductance or inhibiting a potassium-dependent conductance.	Potassium	111-120	leptin	Rattus norvegicus	140-146
16085109-8	2006	Simulations performed with two coupled neurons with parameter values within physiological range show that, without chemical and electrical synapses, potassium lateral diffusion alone can generate and synchronize zero-Ca2+ non-synaptic epileptiform activity.	Potassium	149-158	carbonic anhydrase 2	Homo sapiens	217-220
16192299-9	2006	However, further isolation of background currents by recording in solutions that contained only sodium or only potassium revealed that both leptin and CCK were capable of increasing a sodium-dependent conductance or inhibiting a potassium-dependent conductance.	Potassium	111-120	cholecystokinin	Rattus norvegicus	151-154
16192299-9	2006	However, further isolation of background currents by recording in solutions that contained only sodium or only potassium revealed that both leptin and CCK were capable of increasing a sodium-dependent conductance or inhibiting a potassium-dependent conductance.	Potassium	229-238	leptin	Rattus norvegicus	140-146
16192299-9	2006	However, further isolation of background currents by recording in solutions that contained only sodium or only potassium revealed that both leptin and CCK were capable of increasing a sodium-dependent conductance or inhibiting a potassium-dependent conductance.	Potassium	229-238	cholecystokinin	Rattus norvegicus	151-154
16428287-6	2006	Whether expression of the KS-WNK1 (kidney-specific, KS) is altered in PHA II is not known.	Potassium	26-28	WNK lysine deficient protein kinase 1	Homo sapiens	29-33
16506891-4	2006	hERG-transfected human embryonic kidney-293 cells were cultured on 96-well assay plates and loaded with rubidium ion by incubating in media in which potassium was replaced by 5.4 mM Rb+.	Potassium	149-158	ETS transcription factor ERG	Homo sapiens	0-4
16495758-0	2006	Flunarizine is a highly potent inhibitor of cardiac hERG potassium current.	Potassium	57-66	ETS transcription factor ERG	Homo sapiens	52-56
16495758-3	2006	We examined the effects of flunarizine on potassium currents through cardiac channels encoded by the human ether-a-go-go related gene (hERG) stably expressed in CHO cells.	Potassium	42-51	ETS transcription factor ERG	Homo sapiens	135-139
16495758-4	2006	In this study, we have characterized the effect of flunarizine on biophysical properties of hERG potassium currents with standard whole-cell voltage-clamp techniques.	Potassium	97-106	ETS transcription factor ERG	Homo sapiens	92-96
16495758-6	2006	The effect of flunarizine on hERG potassium current is concentration and time dependent, and displays voltage dependence over the voltage range between -40 and 0 mV.	Potassium	34-43	ETS transcription factor ERG	Homo sapiens	29-33
16278313-0	2006	Adenosine A1 receptor antagonist blunts urinary potassium excretion, but not renal hemodynamic effects, induced by carbonic anhydrase inhibitor in rats.	Potassium	48-57	adenosine A1 receptor	Rattus norvegicus	0-21
16430303-3	2006	The dependence of the resulting circuit elements upon the applied potential was interpreted on the basis of a general approximate approach based on a model of the electrified interphase and on the kinetics of the translocation of potassium and chloride ions across the lipid bilayer, assisted by the OmpF porin.	Potassium	230-239	voltage dependent anion channel 1	Homo sapiens	305-310
16428287-6	2006	Whether expression of the KS-WNK1 (kidney-specific, KS) is altered in PHA II is not known.	Potassium	52-54	WNK lysine deficient protein kinase 1	Homo sapiens	29-33
16428287-7	2006	We found that KS-WNK1 did not inhibit ROMK1 but reversed the inhibition of ROMK1 caused by long WNK1.	Potassium	14-16	WNK lysine deficient protein kinase 1	Homo sapiens	17-21
16428287-7	2006	We found that KS-WNK1 did not inhibit ROMK1 but reversed the inhibition of ROMK1 caused by long WNK1.	Potassium	14-16	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	75-80
16428287-7	2006	We found that KS-WNK1 did not inhibit ROMK1 but reversed the inhibition of ROMK1 caused by long WNK1.	Potassium	14-16	WNK lysine deficient protein kinase 1	Homo sapiens	96-100
16428287-11	2006	Thus, KS-WNK1 is a physiological antagonist of long WNK1.	Potassium	6-8	WNK lysine deficient protein kinase 1	Homo sapiens	9-13
16428287-11	2006	Thus, KS-WNK1 is a physiological antagonist of long WNK1.	Potassium	6-8	WNK lysine deficient protein kinase 1	Homo sapiens	52-56
16260777-0	2006	Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions.	Potassium	53-62	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	87-92
16445274-7	2006	Serum potassium levels can be lowered acutely by using intravenous insulin and glucose, nebulized beta2 agonists, or both.	Potassium	6-15	insulin	Homo sapiens	67-74
16445274-7	2006	Serum potassium levels can be lowered acutely by using intravenous insulin and glucose, nebulized beta2 agonists, or both.	Potassium	6-15	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	98-103
16671491-6	2006	These results implicate AQP4 in water and potassium regulation associated with neuronal activity and seizures.	Potassium	42-51	aquaporin 4	Mus musculus	24-28
17333621-6	2006	The slow inactivating component of integral potassium current was relatively small and had the time constant of inactivation 3 +/- 0.15 s that is typical for delayed rectifier potassium channels of Kv2 and Kv3 subfamilies.	Potassium	44-53	potassium voltage-gated channel subfamily A member 6	Rattus norvegicus	198-201
17333621-6	2006	The slow inactivating component of integral potassium current was relatively small and had the time constant of inactivation 3 +/- 0.15 s that is typical for delayed rectifier potassium channels of Kv2 and Kv3 subfamilies.	Potassium	44-53	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	206-209
16610352-1	2006	The human ether-a-go-go-related gene (hERG) encodes an ion channel subunit underlying IKr, a potassium current required for the normal repolarization of ventricular cells in the human heart.	Potassium	93-102	ETS transcription factor ERG	Homo sapiens	38-42
16563220-2	2006	The major function of Kir is in establishing the high potassium (K+) selectivity of the glial cell membrane and strongly negative resting membrane potential (RMP), which are characteristic physiological properties of glia.	Potassium	54-63	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	22-25
16636594-10	2006	High K+-ATPase activity in the erythrocytes correlated with low plasma potassium.	Potassium	71-80	dynein axonemal heavy chain 8	Homo sapiens	8-14
16399292-1	2006	OBJECTIVE: We sought to assess the role of glucose-insulin-potassium in providing myocardial protection in nondiabetic patients undergoing coronary artery surgery with cardiopulmonary bypass.	Potassium	59-68	insulin	Homo sapiens	51-58
16399292-8	2006	RESULTS: The glucose-insulin-potassium group experienced higher cardiac indices (P &lt; .001) throughout infusion and reduced vascular resistance (P &lt; .001).	Potassium	29-38	insulin	Homo sapiens	21-28
16399292-9	2006	The incidence of low cardiac output episodes was 15.9% (22/138) in the glucose-insulin-potassium group and 27.5% (39/142) in the placebo group (P = .021).	Potassium	87-96	insulin	Homo sapiens	79-86
16399292-10	2006	Inotropes were required in 18.8% (26/138) of the glucose-insulin-potassium group and 40.8% (58/142) of the placebo group (P &lt; .001).	Potassium	65-74	insulin	Homo sapiens	57-64
16399292-11	2006	Fewer patients in the glucose-insulin-potassium group (12.3% [16/133]) versus those in the placebo group (23.4% [32/137]) had significant myocardial injury (P = .017).	Potassium	38-47	insulin	Homo sapiens	30-37
16636594-11	2006	The K+-ATPase activity correlated positively with the amount of potassium administered to dehydrated infants.	Potassium	64-73	dynein axonemal heavy chain 8	Homo sapiens	7-13
16636594-12	2006	CONCLUSION: These findings suggest that the erythrocytes Na+,K+-ATPase and K+-ATPase both protect against plasma potassium abnormalities in dehydrated infants.	Potassium	113-122	dynein axonemal heavy chain 8	Homo sapiens	64-70
16636594-12	2006	CONCLUSION: These findings suggest that the erythrocytes Na+,K+-ATPase and K+-ATPase both protect against plasma potassium abnormalities in dehydrated infants.	Potassium	113-122	dynein axonemal heavy chain 8	Homo sapiens	78-84
16298082-7	2006	In addition, the potassium and capsaicin-stimulated release of immunoreactive calcitonin gene-related peptide from cultures of sensory neurons isolated from Nf1+/- mice was more than double that from cultures of wildtype neurons.	Potassium	17-26	neurofibromin 1	Mus musculus	157-160
16841750-3	2006	According to the Monod type kinetics, the maximum uptake rates (km) of butyric acid (HBu), propionic acid (HPr) and acetic acid (HAc) are testified as 18, 14, 13 d(-1), and their half saturation concentrations (Ks) are 110, 120, 160 g COD/m3, respectively.	Potassium	211-213	haptoglobin-related protein	Homo sapiens	107-110
16225847-1	2005	In this study, we have investigated block of potassium (K(+)) current by neomycin, a large polycation, from the luminal face of the type 3 ryanodine receptor (RyR3).	Potassium	45-54	ryanodine receptor 3	Homo sapiens	132-157
16269203-4	2005	Although the GLAST mRNA expression was increased during glutamate and potassium loading, no changes in the expression were observed during hypoxia and at confluence.	Potassium	70-79	solute carrier family 1 member 3	Rattus norvegicus	13-18
22791335-4	2012	Here, we measured the expression of KS-WNK1 transcript in microdissected renal tubules and found that KS-WNK1 was most abundant in the DCT, followed by cortical thick ascending limb (cTAL), connecting tubule, and cortical collecting duct.	Potassium	36-38	WNK lysine deficient protein kinase 1	Mus musculus	39-43
22791335-4	2012	Here, we measured the expression of KS-WNK1 transcript in microdissected renal tubules and found that KS-WNK1 was most abundant in the DCT, followed by cortical thick ascending limb (cTAL), connecting tubule, and cortical collecting duct.	Potassium	36-38	WNK lysine deficient protein kinase 1	Mus musculus	105-109
22791335-5	2012	A high K(+) diet enhanced the expression of KS-WNK1 in the DCT and cTAL, selectively.	Potassium	44-46	WNK lysine deficient protein kinase 1	Mus musculus	47-51
22791335-8	2012	Furosemide-sensitive Na(+) reabsorption in cTAL was higher in KS-WNK1-knockout (KO) mice than in wild-type.	Potassium	62-64	WNK lysine deficient protein kinase 1	Mus musculus	65-69
22791335-9	2012	A high-K(+) diet inhibited Na(+) reabsorption in cTAL from wild-type mice, but the inhibition was eliminated in KS-WNK1-KO mice.	Potassium	112-114	WNK lysine deficient protein kinase 1	Mus musculus	115-119
22791335-13	2012	Thus KS-WNK1 inhibits Na(+) reabsorption in cTAL and mediates the inhibition of Na(+) reabsorption in the segment by a high-K diet.	Potassium	5-7	WNK lysine deficient protein kinase 1	Mus musculus	8-12
16225847-1	2005	In this study, we have investigated block of potassium (K(+)) current by neomycin, a large polycation, from the luminal face of the type 3 ryanodine receptor (RyR3).	Potassium	45-54	ryanodine receptor 3	Homo sapiens	159-163
16316977-12	2005	It is discussed that this hypersensitive response of AKT2 to phosphorylation equips a cell with the versatility to establish a potassium gradient and to make efficient use of it.	Potassium	127-136	potassium transport 2/3	Arabidopsis thaliana	53-57
16149055-10	2005	Potassium depletion blocked LRP-1 endocytosis but did not inhibit trafficking of LRP-1 from rafts into detergent-soluble microdomains.	Potassium	0-9	LDL receptor related protein 1	Homo sapiens	28-33
16427537-3	2005	Changing insulin therapy can also have profound effects on potassium homeostasis in certain patients.	Potassium	59-68	insulin	Homo sapiens	9-16
16427537-4	2005	This case demonstrates that changes in insulin therapy warrant not only close monitoring of blood glucose, but also of serum potassium.	Potassium	125-134	insulin	Homo sapiens	39-46
16109388-9	2005	Coexpression of wtKCNQ1+KCNE1 subunits induced the typical slowly activating and voltage-dependent delayed rectifier K(+) current, I(Ks).	Potassium	133-135	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	24-29
16393152-4	2005	Here, we investigated the hypothesis that impairment of potassium uptake through astrocyte inward rectifier potassium (Kir) channels may contribute to epileptogenesis in Tsc1(GFAP)CKO mice.	Potassium	56-65	TSC complex subunit 1	Mus musculus	170-174
16393152-11	2005	Last, hippocampal slices from Tsc1(GFAP)CKO mice exhibited decreased astrocytic Kir currents, as well as increased susceptibility to potassium-induced epileptiform activity.	Potassium	133-142	TSC complex subunit 1	Mus musculus	30-34
16393152-11	2005	Last, hippocampal slices from Tsc1(GFAP)CKO mice exhibited decreased astrocytic Kir currents, as well as increased susceptibility to potassium-induced epileptiform activity.	Potassium	133-142	glial fibrillary acidic protein	Mus musculus	35-39
16263909-0	2005	KAT1 inactivates at sub-millimolar concentrations of external potassium.	Potassium	62-71	kynurenine aminotransferase 1	Homo sapiens	0-4
16267597-2	2005	Fluorescence melting experiments show that this intramolecular quadruplex, which is more stable in potassium- than sodium-containing buffers, shows considerable hysteresis between the melting and annealing profiles, even when heated at a rate of 0.05 degrees C min(-1).	Potassium	99-108	CD59 molecule (CD59 blood group)	Homo sapiens	261-267
16247802-0	2005	Postsynaptic excitation of prefrontal cortical pyramidal neurons by hypocretin-1/orexin A through the inhibition of potassium currents.	Potassium	116-125	hypocretin neuropeptide precursor	Rattus norvegicus	81-89
16604470-3	2005	We found that phloxine B stimulates and inhibits channel activity of wild-type CFTR (Ks = 3.2 +/- 1.6 microM: , Ki = 38 +/- 1.4 microM: ) and delF508 CFTR (Ks = 3 +/- 1.8 microM: , Ki = 33 +/- 1 microM: ).	Potassium	85-87	CF transmembrane conductance regulator	Homo sapiens	79-83
16604470-4	2005	However, CFTR channels with the LSGDQ mutated motif (mutation G551D) are activated (Ks = 2 +/- 1.13 microM: ) but not inhibited by phloxine B.	Potassium	84-86	CF transmembrane conductance regulator	Homo sapiens	9-13
16359386-6	2005	The athkt1 mutant alleles had a smaller and inverse influence on the potassium (K+) content compared with the Na+ content of the xylem, suggesting that K+ transport may be indirectly affected.	Potassium	69-78	high-affinity K+ transporter 1	Arabidopsis thaliana	4-10
16358319-1	2005	The functional expression of the mouse Kir2.1 potassium channel in yeast cells lacking transport systems for potassium and sodium efflux (ena1-4delta nha1delta) resulted in increased cell sensitivity to high external concentrations of potassium.	Potassium	46-55	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	39-45
16358319-1	2005	The functional expression of the mouse Kir2.1 potassium channel in yeast cells lacking transport systems for potassium and sodium efflux (ena1-4delta nha1delta) resulted in increased cell sensitivity to high external concentrations of potassium.	Potassium	109-118	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	39-45
16358319-7	2005	The use of a mutant strain lacking both potassium efflux and uptake transporters (ena1-4delta nha1delta trk1delta trk2delta) enabled the monitoring of channel activity on two levels--the provision of the necessary amount of intracellular K+ in media with low potassium concentrations, and simultaneously, the channel"s contribution to cell potassium sensitivity in the presence of high external K+.	Potassium	40-49	Trk1p	Saccharomyces cerevisiae S288C	82-123
16358319-7	2005	The use of a mutant strain lacking both potassium efflux and uptake transporters (ena1-4delta nha1delta trk1delta trk2delta) enabled the monitoring of channel activity on two levels--the provision of the necessary amount of intracellular K+ in media with low potassium concentrations, and simultaneously, the channel"s contribution to cell potassium sensitivity in the presence of high external K+.	Potassium	259-268	Trk1p	Saccharomyces cerevisiae S288C	82-123
16358319-7	2005	The use of a mutant strain lacking both potassium efflux and uptake transporters (ena1-4delta nha1delta trk1delta trk2delta) enabled the monitoring of channel activity on two levels--the provision of the necessary amount of intracellular K+ in media with low potassium concentrations, and simultaneously, the channel"s contribution to cell potassium sensitivity in the presence of high external K+.	Potassium	259-268	Trk1p	Saccharomyces cerevisiae S288C	82-123
16118216-1	2005	The cell surface density of functional Kir1.1 (ROMK, KCNJ1) channels in the renal collecting duct is precisely regulated to maintain potassium balance.	Potassium	133-142	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	39-45
16267222-1	2005	The mammalian voltage-dependent KCNQ channels are responsible for distinct types of native potassium currents and are associated with several human diseases.	Potassium	91-100	KCNQ potassium channel	Drosophila melanogaster	32-36
16388096-0	2005	Ghrelin reduces voltage-gated potassium currents in GH3 cells via cyclic GMP pathways.	Potassium	30-39	ghrelin and obestatin prepropeptide	Rattus norvegicus	0-7
16383643-3	2005	These two are coupled to interact with each other in the combined model, and two basic assumptions are made on the basis of biological observations: The conductance gK(ATP) for the ATP-dependent potassium current is a decreasing function of the glucose concentration whereas the insulin secretion rate is given by a function of the intracellular calcium concentration.	Potassium	195-204	insulin	Homo sapiens	279-286
16118216-1	2005	The cell surface density of functional Kir1.1 (ROMK, KCNJ1) channels in the renal collecting duct is precisely regulated to maintain potassium balance.	Potassium	133-142	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	47-51
16118216-1	2005	The cell surface density of functional Kir1.1 (ROMK, KCNJ1) channels in the renal collecting duct is precisely regulated to maintain potassium balance.	Potassium	133-142	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	53-58
16239639-0	2005	Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.	Potassium	157-166	vascular endothelial growth factor A	Homo sapiens	128-132
16002097-0	2005	G-protein beta-3 subunit gene C825 T polymorphism: influence on plasma sodium and potassium concentrations in essential hypertensive patients.	Potassium	82-91	G protein subunit beta 3	Homo sapiens	0-16
16002097-10	2005	Our data demonstrate an association between the C825T polymorphism of the GNB3 and plasma sodium and potassium concentrations in EHP, as expression of an increase in NHE-1 activity, without modifications in PRA nor relationship with salt sensitivity.	Potassium	101-110	G protein subunit beta 3	Homo sapiens	74-78
16227078-8	2005	The water-soluble fraction of potassium, lead and manganese increased in both P2 and P5.	Potassium	30-39	tissue factor pathway inhibitor 2	Homo sapiens	78-87
16183425-2	2005	Exogenous insulin stimulates this disposal by enhancing potassium uptake into cells in hemodialysis (HD) patients and healthy subjects.	Potassium	56-65	insulin	Homo sapiens	10-17
16221865-4	2005	However, in response to low-potassium or excitotoxic glutamate conditions that induce neuronal cell death, HDAC4 rapidly translocates into the nucleus of cultured CGNs.	Potassium	28-37	histone deacetylase 4	Mus musculus	107-112
16081479-6	2005	CFTR was activated in myocytes maintained in medium containing either high potassium or 5-hydroxytryptamine (5-HT) and was inhibited by CFTR(inh)-172, glibenclamide and diphenylamine-2,2"-dicarboxylic acid (DPC).	Potassium	75-84	cystic fibrosis transmembrane conductance regulator	Mus musculus	0-4
16081479-6	2005	CFTR was activated in myocytes maintained in medium containing either high potassium or 5-hydroxytryptamine (5-HT) and was inhibited by CFTR(inh)-172, glibenclamide and diphenylamine-2,2"-dicarboxylic acid (DPC).	Potassium	75-84	cystic fibrosis transmembrane conductance regulator	Mus musculus	136-140
16183425-8	2005	In HD patients, the decrease in serum potassium levels was dependent on the increase in serum insulin levels and was more prominent when 150 g of glucose was administered.	Potassium	38-47	insulin	Homo sapiens	94-101
16183425-9	2005	In HD patients, the decrease in serum potassium levels correlated negatively (r = -0.45; P &lt; 0.001) with the increase in serum insulin levels, and maximal decrease in serum potassium levels correlated negatively (r = -0.54; P &lt; 0.001) with maximal increase in serum insulin levels.	Potassium	38-47	insulin	Homo sapiens	130-137
16183425-9	2005	In HD patients, the decrease in serum potassium levels correlated negatively (r = -0.45; P &lt; 0.001) with the increase in serum insulin levels, and maximal decrease in serum potassium levels correlated negatively (r = -0.54; P &lt; 0.001) with maximal increase in serum insulin levels.	Potassium	38-47	insulin	Homo sapiens	272-279
16183425-10	2005	CONCLUSION: Endogenous production of physiological concentrations of insulin in response to exogenous glucose administration decreases serum potassium levels only in HD patients, independently of plasma aldosterone and epinephrine levels.	Potassium	141-150	insulin	Homo sapiens	69-76
16093448-3	2005	Patients who have congenital NDI and bear mutations in the AVPR2 or AQP2 genes have a "pure" NDI phenotype with loss of water but normal conservation of sodium, potassium, chloride, and calcium.	Potassium	161-170	arginine vasopressin receptor 2	Homo sapiens	59-64
15928025-11	2005	Overexpression of PANDER in mouse islets or addition of recombinant PANDER decreased insulin secretion induced by carbachol plus glucose or high potassium but not that by glucose alone.	Potassium	145-154	FAM3 metabolism regulating signaling molecule B	Mus musculus	18-24
15928025-11	2005	Overexpression of PANDER in mouse islets or addition of recombinant PANDER decreased insulin secretion induced by carbachol plus glucose or high potassium but not that by glucose alone.	Potassium	145-154	FAM3 metabolism regulating signaling molecule B	Mus musculus	68-74
16248284-1	2005	KS Biomedix (formerly Avicenna Medica; now a subsidiary of the Xenova group) and Nycomed, together with Japanese licensee Sosei and Chinese licensee PharmaEngine, are developing TransMID, a transferrin-mediated diphtheria toxin delivery system for the potential treatment of adult, recurrent, inoperable, high-grade glioma (as TransMID-107R).	Potassium	0-2	transferrin	Homo sapiens	190-201
16093448-3	2005	Patients who have congenital NDI and bear mutations in the AVPR2 or AQP2 genes have a "pure" NDI phenotype with loss of water but normal conservation of sodium, potassium, chloride, and calcium.	Potassium	161-170	aquaporin 2	Homo sapiens	68-72
16164626-10	2005	In contrast, Ka/Ks analysis for URAT1 suggests decelerated selection pressure.	Potassium	16-18	solute carrier family 22 member 12	Homo sapiens	32-37
16214950-6	2005	Furthermore, angiotensin II, potassium ions and ACTH were all shown to induce ERK1 and ERK2 phosphorylation in the ZG.	Potassium	29-38	mitogen activated protein kinase 3	Rattus norvegicus	78-82
16214950-6	2005	Furthermore, angiotensin II, potassium ions and ACTH were all shown to induce ERK1 and ERK2 phosphorylation in the ZG.	Potassium	29-38	mitogen activated protein kinase 1	Rattus norvegicus	87-91
16222095-0	2005	[The structure and phosphorus or potassium deficiency induced expression of a calmodulin-like protein gene in Arabidopsis].	Potassium	33-42	calmodulin-like protein	Arabidopsis thaliana	78-101
16164646-9	2005	In rats, prolactin infusion resulted in an increase in urinary sodium, potassium, and water excretion.	Potassium	71-80	prolactin	Rattus norvegicus	9-18
16132269-1	2005	Intracellular dialysis and membrane voltage clamping were used to show that He-Ne laser irradiation of a pond snail neuron at a dose of 0.7 x 10(-4) J (power density 1.5 x 10(2) W/m2) increases the amplitude of the potential-dependent slow potassium current, while a dose of 0.7 x 10(-3) J decreases this current.	Potassium	240-249	snail family transcriptional repressor 1	Homo sapiens	110-115
16201664-5	2005	A relation describing this condition has been derived: PH2SS = [Rcorr/ ks]2 For the granular irons considered in this study, PH2SS values vary from less than one to eight bars, in contrast to the calculated thermodynamic equilibrium PH2 values for anaerobic corrosion, which range from 138 to 631 bar depending on the assumed product of corrosion.	Potassium	71-73	polyhomeotic homolog 2	Homo sapiens	55-58
16148750-0	2005	Effects of copper on A-type potassium currents in acutely dissociated rat hippocampal CA1 neurons.	Potassium	28-37	carbonic anhydrase 1	Rattus norvegicus	86-89
16148750-5	2005	This study indicated that copper reversibly inhibits the hippocampal CA1 neuronal voltage-gated A-type potassium current in a dose-dependent and voltage-dependent manner, and such actions are likely involved in the regulation of the neuronal excitability and the pathophysiology of Wilson"s disease.	Potassium	103-112	carbonic anhydrase 1	Rattus norvegicus	69-72
16039997-1	2005	We previously showed that the Kaposi Sarcoma line KS-IMM express a functional Met tyrosine kinase receptor, which, upon HGF stimulation, activates motogenic, proliferative, and invasive responses.	Potassium	50-52	hepatocyte growth factor	Homo sapiens	120-123
16308426-5	2005	At hyperpolarizing voltages, ajmaline at high concentration of 300 micromol/l reduced the inward moiety of time-independent potassium current (IK1) by 36%.	Potassium	124-133	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	143-146
16002409-5	2005	The replacement of Ser-43 by Ala ablates the PKA phosphorylation of N-T Yotiao and markedly diminishes the functional response of the wild type and pseudo-phosphorylated I(Ks) channel to cAMP but neither prevents the PKA phosphorylation of KCNQ1 nor its binding to Yotiao.	Potassium	172-174	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	240-245
16191494-12	2005	Intravenously administered insulin should be withheld until the serum potassium concentration is (3)3.3 mEq/L.	Potassium	70-79	insulin	Homo sapiens	27-34
16176344-0	2005	Up-regulation of lysosomal cathepsin L and autophagy during neuronal death induced by reduced serum and potassium.	Potassium	104-113	cathepsin L	Rattus norvegicus	27-38
16176344-6	2005	Addition of selective cathepsin L inhibitors or of the autophagy inhibitor 3-methyladenine provided partial protection against serum and potassium deprivation-induced death.	Potassium	137-146	cathepsin L	Rattus norvegicus	22-33
16176344-7	2005	Our data also show that combining cathepsin L inhibitors and caspase-3 inhibitors leads to a synergistic neuroprotective effect against serum and potassium deprivation.	Potassium	146-155	cathepsin L	Rattus norvegicus	34-45
16176344-7	2005	Our data also show that combining cathepsin L inhibitors and caspase-3 inhibitors leads to a synergistic neuroprotective effect against serum and potassium deprivation.	Potassium	146-155	caspase 3	Rattus norvegicus	61-70
16055093-0	2005	Thyrotropin-releasing hormone (protirelin) inhibits potassium-stimulated glutamate and aspartate release from hippocampal slices in vitro.	Potassium	52-61	thyrotropin releasing hormone	Rattus norvegicus	0-29
16000145-1	2005	Mounting evidence reveals that ATP-sensitive potassium (K(ATP)) channel openers (KCOs) exert significant neuroprotection in vivo and in vitro in several models of Parkinson"s disease (PD).	Potassium	45-54	ATPase phospholipid transporting 8A2	Homo sapiens	31-34
16098519-0	2005	Mammalian NHE2 Na(+)/H+ exchanger mediates efflux of potassium upon heterologous expression in yeast.	Potassium	53-62	solute carrier family 9 member A2	Rattus norvegicus	10-14
16098519-5	2005	We demonstrate for the first time that a mammalian Na(+)/H+ exchanger transports alkali metal cations in yeast in the opposite direction than in mammalian cells, and that the substrate specificity of the rat NHE2 exchanger is limited only to potassium cations upon expression in yeast cells.	Potassium	242-251	solute carrier family 9 member A2	Rattus norvegicus	208-212
15885672-11	2005	Inhibition of COX-2 with NS-398 or SC-58125 partially--but significantly--alleviates agonist-induced but not potassium-induced contractile hyperreactivity.	Potassium	109-118	prostaglandin-endoperoxide synthase 2	Mus musculus	14-19
16014321-7	2005	Finally, animals that are defective in HLH-17 via RNAi display egg-laying defects, while those carrying null mutations in hlh-17 do not develop beyond the L2 stage and are less attracted to potassium and sodium ions.	Potassium	190-199	Helix-loop-helix protein 17	Caenorhabditis elegans	122-128
16342681-2	2005	METHODS: Whole cell patch clamp technique was used to record potassium currents including fast transient outward current (I(KA)) and delayed rectifier current (I(Kdr)).	Potassium	61-70	kinase insert domain receptor	Rattus norvegicus	162-165
16093392-5	2005	The inhibitory NPY actions were mediated by postsynaptic activation of G-protein-linked inwardly rectifying potassium (GIRK) and depression of voltage-gated calcium currents via Y1 and Y2 receptor subtypes.	Potassium	108-117	neuropeptide Y	Mus musculus	15-18
15950200-6	2005	Mutant KCNQ1 channels were heterologously expressed in Xenopus oocytes, and potassium currents were recorded using the two-microelectrode voltage clamp technique.	Potassium	76-85	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	7-12
15955806-7	2005	Expression of K(V)1.4 protein was also demonstrated in human beta-cells; GIP treatment resulting in similar decreases in A-type potassium current peak amplitude to those in HEK293 cells.	Potassium	128-137	potassium voltage-gated channel subfamily A member 4	Homo sapiens	14-21
15955806-7	2005	Expression of K(V)1.4 protein was also demonstrated in human beta-cells; GIP treatment resulting in similar decreases in A-type potassium current peak amplitude to those in HEK293 cells.	Potassium	128-137	gastric inhibitory polypeptide	Homo sapiens	73-76
15955806-9	2005	These results strongly support an important novel role for GIP in regulating K(V)1.4 cell surface expression and modulation of A-type potassium currents, which is likely to be critically important for its insulinotropic action.	Potassium	134-143	gastric inhibitory polypeptide	Homo sapiens	59-62
16040808-6	2005	Second, using physiological studies, we demonstrate that NPY specifically enhances an inwardly rectifying potassium current via NPY-Y1 receptors.	Potassium	106-115	neuropeptide Y	Rattus norvegicus	57-60
16040808-6	2005	Second, using physiological studies, we demonstrate that NPY specifically enhances an inwardly rectifying potassium current via NPY-Y1 receptors.	Potassium	106-115	neuropeptide Y	Rattus norvegicus	128-131
16834043-4	2005	Analytical and numerical simulations indicate that there is a significant quadrupolar interaction present at both potassium nuclei (C(Q)(39K) = 2.55(6)/2.67(8) MHz and 4.69(8) MHz for CpK (static/MAS) and Cp*K, respectively).	Potassium	114-123	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	184-187
16834043-5	2005	Experimental quadrupolar asymmetry parameters suggest that both structures are bent about the potassium atoms (eta(Q)(39K) = 0.28(3)/0.29(3) for CpK (static/MAS) and eta(Q)(39K) = 0.30(3) for Cp*K).	Potassium	94-103	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	145-148
16033419-1	2005	Inwardly rectifying potassium (Kir) channels in Muller glia play a critical role in the spatial buffering of potassium ions that accumulate during retinal activity.	Potassium	20-29	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	31-34
32689163-8	2005	Antisense AtCNGC10 plants had 50% less potassium than wild type Columbia.	Potassium	39-48	cyclic nucleotide gated channel 10	Arabidopsis thaliana	10-18
15998706-10	2005	Mineralocorticoid receptor antagonism prevents the effect of activation of the renin-angiotensin-aldosterone system on PAI-1 antigen in normotensive subjects and improves fibrinolytic balance in hypertensive subjects through a potassium-independent mechanism.	Potassium	227-236	nuclear receptor subfamily 3 group C member 2	Homo sapiens	0-26
15998706-10	2005	Mineralocorticoid receptor antagonism prevents the effect of activation of the renin-angiotensin-aldosterone system on PAI-1 antigen in normotensive subjects and improves fibrinolytic balance in hypertensive subjects through a potassium-independent mechanism.	Potassium	227-236	renin	Homo sapiens	79-84
15987778-1	2005	The renal outer-medullary K+ channel (ROMK; Kir1.1) mediates K+ secretion in the renal mammalian nephron that is critical to both sodium and potassium homeostasis.	Potassium	141-150	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	4-36
21162184-0	2005	[Effects of sodium metabisulfite on potassium currents in acutely isolated rat hippocampal CA1 neurons].	Potassium	36-45	carbonic anhydrase 1	Rattus norvegicus	91-94
16043459-5	2005	HUCB-NSCD acquired neuronal phenotypes and displayed an inward rectifying potassium current (Kir) and an outward rectifying potassium current (I(K+)).	Potassium	74-83	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	93-96
16018996-1	2005	Linopirdine was developed as a cognitive enhancing molecule and demonstrated to specifically block the potassium current generated by the brain specific KCNQ2-KCNQ3 proteins (M-channel).	Potassium	103-112	potassium voltage-gated channel subfamily Q member 2	Rattus norvegicus	153-158
16018996-1	2005	Linopirdine was developed as a cognitive enhancing molecule and demonstrated to specifically block the potassium current generated by the brain specific KCNQ2-KCNQ3 proteins (M-channel).	Potassium	103-112	potassium voltage-gated channel subfamily Q member 3	Rattus norvegicus	159-164
15987778-1	2005	The renal outer-medullary K+ channel (ROMK; Kir1.1) mediates K+ secretion in the renal mammalian nephron that is critical to both sodium and potassium homeostasis.	Potassium	141-150	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	38-42
15987778-1	2005	The renal outer-medullary K+ channel (ROMK; Kir1.1) mediates K+ secretion in the renal mammalian nephron that is critical to both sodium and potassium homeostasis.	Potassium	141-150	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	44-50
15983966-8	2005	Serum potassium levels correlated with overall Subjective Global Assessment score (r = 0.276; P &lt; 0.001) and serum albumin level (r = 0.173; P = 0.005) and inversely with Charlson comorbidity score (r = -0.155; P = 0.011).	Potassium	6-15	albumin	Homo sapiens	118-125
15907795-3	2005	The decreased surface expression of ROMK caused by mutant WNK4 was postulated to be a mechanism for decreased potassium secretion in distal nephrons that would presumably lead to hyperkalemia.	Potassium	110-119	potassium inwardly-rectifying channel, subfamily J, member 1	Mus musculus	36-40
15907795-3	2005	The decreased surface expression of ROMK caused by mutant WNK4 was postulated to be a mechanism for decreased potassium secretion in distal nephrons that would presumably lead to hyperkalemia.	Potassium	110-119	WNK lysine deficient protein kinase 4	Mus musculus	58-62
15894288-3	2005	The chimeras were screened in a potassium-uptake deficient yeast strain to identify those, which mediate potassium inward currents, i.e., which are functionally equivalent to KAT1.	Potassium	32-41	histone acetyltransferase catalytic subunit HAT1	Saccharomyces cerevisiae S288C	175-179
15894288-3	2005	The chimeras were screened in a potassium-uptake deficient yeast strain to identify those, which mediate potassium inward currents, i.e., which are functionally equivalent to KAT1.	Potassium	105-114	histone acetyltransferase catalytic subunit HAT1	Saccharomyces cerevisiae S288C	175-179
15957054-1	2005	Reaction of potassium salts of sterically demanding pyrazolates (pz = bis-3,5-tert-butylpyrazolate, pz= bis-3,5-tert-butyl-4-methylpyrazolate) with Re2O7 affords soluble eta2-pyrazolate complexes of the type [(eta2-pz)ReO3(THF)n](1: pz, n= 1 and 2: pz, n= 0).	Potassium	12-21	DNA polymerase iota	Homo sapiens	170-174
15953346-2	2005	Removal of depolarizing potassium triggers CGN apoptosis that requires induction of Bim, a BH3-only Bcl-2 family member.	Potassium	24-33	cingulin	Homo sapiens	43-46
15953346-2	2005	Removal of depolarizing potassium triggers CGN apoptosis that requires induction of Bim, a BH3-only Bcl-2 family member.	Potassium	24-33	BCL2 like 11	Homo sapiens	84-87
15953346-2	2005	Removal of depolarizing potassium triggers CGN apoptosis that requires induction of Bim, a BH3-only Bcl-2 family member.	Potassium	24-33	BCL2 apoptosis regulator	Homo sapiens	100-105
15922632-0	2005	Additive effects of ziprasidone and D,L-sotalol on the action potential in rabbit Purkinje fibres and on the hERG potassium current.	Potassium	114-123	ETS transcription factor ERG	Homo sapiens	109-113
15779084-6	2005	The effects of AC stimulation required a permissive role for GIRK2 (or K(IR)3.2) potassium channels and were mimicked by raising extracellular potassium concentrations.	Potassium	81-90	potassium inwardly rectifying channel subfamily J member 6	Homo sapiens	61-66
15931062-5	2005	Whole-cell recording in CA1 pyramidal neurons showed a significantly greater 5HT1A receptor-mediated potassium current in Galphaz knock-out mice.	Potassium	101-110	carbonic anhydrase 1	Mus musculus	24-27
15931062-5	2005	Whole-cell recording in CA1 pyramidal neurons showed a significantly greater 5HT1A receptor-mediated potassium current in Galphaz knock-out mice.	Potassium	101-110	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	77-91
15957054-1	2005	Reaction of potassium salts of sterically demanding pyrazolates (pz = bis-3,5-tert-butylpyrazolate, pz= bis-3,5-tert-butyl-4-methylpyrazolate) with Re2O7 affords soluble eta2-pyrazolate complexes of the type [(eta2-pz)ReO3(THF)n](1: pz, n= 1 and 2: pz, n= 0).	Potassium	12-21	DNA polymerase iota	Homo sapiens	210-214
15895241-11	2005	In summary, these findings support the proposed role of ROMK channels in potassium recycling and in the regulation of K+ secretion and present a rationale for the phenotype observed in patients with ROMK deficiency.	Potassium	73-82	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	56-60
15950778-6	2005	Finally, we examined the pharmacological inhibitors of GSK3beta, GSK3 inhibitor I, TDZD-8, and SB-415286, for their ability to prevent low potassium (LK)-induced apoptosis.	Potassium	139-148	glycogen synthase kinase 3 beta	Rattus norvegicus	55-63
16080838-1	2005	OBJECTIVE: This study was designed to evaluate reperfusion therapy, co-administered with high dose glucose-insulin-potassium (GIK) treatment on serum soluble Fas/APO-1 (sFas) and Fas ligand (sFasL) concentration in Acute Myocardial Infarction (AMI) patients.	Potassium	115-124	Fas cell surface death receptor	Homo sapiens	162-167
16080838-1	2005	OBJECTIVE: This study was designed to evaluate reperfusion therapy, co-administered with high dose glucose-insulin-potassium (GIK) treatment on serum soluble Fas/APO-1 (sFas) and Fas ligand (sFasL) concentration in Acute Myocardial Infarction (AMI) patients.	Potassium	115-124	Fas ligand	Homo sapiens	179-189
15947203-4	2005	To extend our understanding of the role of Ptr3p and Ssy5p in this amino acid sensing process, we have isolated constitutive gain-of-function mutants in these two components by using a genetic screening in which potassium uptake is made dependent on amino acid signaling.	Potassium	212-221	Ptr3p	Saccharomyces cerevisiae S288C	43-48
15947203-4	2005	To extend our understanding of the role of Ptr3p and Ssy5p in this amino acid sensing process, we have isolated constitutive gain-of-function mutants in these two components by using a genetic screening in which potassium uptake is made dependent on amino acid signaling.	Potassium	212-221	Ssy5p	Saccharomyces cerevisiae S288C	53-58
15729735-9	2005	These results suggest that three different currents are implicated in rapid NGF-induced membrane voltage changes, namely an acutely activated Na+ current, Ca2+-dependent potassium currents and non-selective cation currents.	Potassium	170-179	nerve growth factor	Rattus norvegicus	76-79
16007460-6	2005	HERG potassium currents expressed in Xenopus oocytes were measured with a two-microelectrode voltage clamp.	Potassium	5-14	potassium voltage-gated channel subfamily H member 2	Homo sapiens	0-4
15800067-3	2005	We previously demonstrated that the activation of integrins containing the beta(1) subunit leads to a selective increase in potassium currents carried by the human ether-a-go-go-related gene (hERG) channels in neuroblastoma and leukemia cells; this current activation modulates adhesion-dependent differentiation in these cells.	Potassium	124-133	ETS transcription factor ERG	Homo sapiens	192-196
25696497-8	2005	In order to further stimulate potassium transport into the cell, insulin was administered.	Potassium	30-39	insulin	Homo sapiens	65-72
15883206-13	2005	These nongenomic functional effects of insulin may be of clinical relevance, eg, during insulin-glucose-potassium infusions.	Potassium	104-113	insulin	Homo sapiens	39-46
15921531-8	2005	To demonstrate the flexibility to use diverse models of molecular evolution and dissect the nature of the evolutionary process Vestige was used to footprint the Ka/Ks ratio in primate BRCA1 with a codon model of evolution.	Potassium	164-166	BRCA1 DNA repair associated	Homo sapiens	184-189
15883206-13	2005	These nongenomic functional effects of insulin may be of clinical relevance, eg, during insulin-glucose-potassium infusions.	Potassium	104-113	insulin	Homo sapiens	88-95
15804582-5	2005	Functional expression of one of the DMIH variants with a long N-terminus in HEK293 cells produced unitary currents that were preferentially selective for potassium over sodium ions and were activated by hyperpolarizing voltage steps.	Potassium	154-163	I[[h]] channel	Drosophila melanogaster	36-40
15862311-2	2005	Here, we show that secretory phospholipases A(2)s (sPLA(2)s) rescue CGNs from apoptosis after potassium deprivation.	Potassium	94-103	phospholipase A2 group IID	Homo sapiens	51-59
15811898-2	2005	DATA SOURCES: Evidence of efficacy for high-dose insulin therapy with supplemental dextrose and potassium was sought by performing a search of MEDLINE and Toxline between 1966 and July 2004 using combinations of the terms calcium-channel blocker, overdose, poisoning, antidote, and insulin.	Potassium	96-105	insulin	Homo sapiens	49-56
15811898-6	2005	DATA SYNTHESIS: Animal models of CCB overdose demonstrate that high-dose insulin with supplemental dextrose and potassium was a more effective therapy than calcium, glucagon, or catecholamines.	Potassium	112-121	insulin	Homo sapiens	73-80
15718277-2	2005	We found that the cADPR antagonist, 8-Br-cADPR, substantially diminished the secretion of ACTH induced by CRH and potassium in these cells, whereas xestospongin C, an inositol 1,4,5-triphosphate receptor antagonist, had no effect.	Potassium	114-123	pro-opiomelanocortin-alpha	Mus musculus	90-94
15705650-0	2005	Extracellular potassium effects are conserved within the rat erg K+ channel family.	Potassium	14-23	ETS transcription factor ERG	Rattus norvegicus	61-64
15946459-10	2005	In patients with central obesity, high levels of PRA, aldosterone and ACE with sodium retention and potassium loss and high insulin levels, were found.	Potassium	100-109	angiotensin I converting enzyme	Homo sapiens	70-73
15731188-4	2005	Thapsigargin also produced a dramatic potentiation of dendritic vasopressin release evoked by osmotic or high potassium stimulation.	Potassium	110-119	arginine vasopressin	Rattus norvegicus	64-75
15757638-0	2005	ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.	Potassium	27-36	mitogen-activated protein kinase 1	Homo sapiens	84-87
15598972-4	2005	Enhancement of KCNQ2/Q3 potassium currents may provide an important target for antiepileptic drug development.	Potassium	24-33	potassium voltage-gated channel subfamily KQT member 2	Cricetulus griseus	15-20
15725624-10	2005	The enzyme was active at temperatures up to 70 degrees C and, using circular dichroism spectroscopy, shown to denature at temperatures approaching 80 degrees C. Considering the high intracellular potassium ion concentration in M. thermautotrophicus, our results suggest that the characterized thermophilic enzyme acts as an AP endonuclease in vivo with similar activities as Ape1.	Potassium	196-205	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	375-379
15630079-0	2005	Glycogen synthase kinase 3 activity mediates neuronal pentraxin 1 expression and cell death induced by potassium deprivation in cerebellar granule cells.	Potassium	103-112	neuronal pentraxin 1	Homo sapiens	45-65
15630079-1	2005	Expression of neuronal pentraxin 1 (NP1) is part of the apoptotic cell death program activated in mature cerebellar granule neurons when potassium concentrations drop below depolarizing levels.	Potassium	137-146	neuronal pentraxin 1	Homo sapiens	14-34
15630079-1	2005	Expression of neuronal pentraxin 1 (NP1) is part of the apoptotic cell death program activated in mature cerebellar granule neurons when potassium concentrations drop below depolarizing levels.	Potassium	137-146	neuronal pentraxin 1	Homo sapiens	36-39
15630079-5	2005	Both activation of the phosphatidylinositol 3-kinase/Akt (PI-3-K/AKT) pathway by insulin-like growth factor I and pharmacological blockage of the stress activated c-Jun NH(2)-terminal kinase (JNK) offer transitory neuroprotection from the cell death evoked by nondepolarizing concentrations of potassium.	Potassium	294-303	AKT serine/threonine kinase 1	Homo sapiens	53-56
15630079-5	2005	Both activation of the phosphatidylinositol 3-kinase/Akt (PI-3-K/AKT) pathway by insulin-like growth factor I and pharmacological blockage of the stress activated c-Jun NH(2)-terminal kinase (JNK) offer transitory neuroprotection from the cell death evoked by nondepolarizing concentrations of potassium.	Potassium	294-303	mitogen-activated protein kinase 8	Homo sapiens	163-190
15630079-5	2005	Both activation of the phosphatidylinositol 3-kinase/Akt (PI-3-K/AKT) pathway by insulin-like growth factor I and pharmacological blockage of the stress activated c-Jun NH(2)-terminal kinase (JNK) offer transitory neuroprotection from the cell death evoked by nondepolarizing concentrations of potassium.	Potassium	294-303	mitogen-activated protein kinase 8	Homo sapiens	192-195
15630079-6	2005	However, neither of these neuroprotective treatments prevents the overexpression of NP1 upon potassium depletion, indicating that nondepolarizing conditions activate additional cell death signaling pathways.	Potassium	93-102	neuronal pentraxin 1	Homo sapiens	84-87
15630079-8	2005	In contrast, impairing the activity of glycogen synthase kinase 3 (GSK3) completely blocks NP1 overexpression induced by potassium depletion and provides transient protection against cell death.	Potassium	121-130	neuronal pentraxin 1	Homo sapiens	91-94
15630079-9	2005	Moreover, simultaneous pharmacological blockage of both JNK and GSK3 activities provides long-term protection against the cell death evoked by potassium depletion.	Potassium	143-152	mitogen-activated protein kinase 8	Homo sapiens	56-59
15630079-10	2005	These results show that both the JNK and GSK3 signaling pathways are the main routes by which potassium deprivation activates apoptotic cell death, and that NP1 overexpression is regulated by GSK3 activity independently of the PI-3-K/AKT or JNK pathway.	Potassium	94-103	mitogen-activated protein kinase 8	Homo sapiens	33-36
15660259-1	2005	The potassium channel KCNQ4, expressed in the mammalian cochlea, has been associated tentatively with an outer hair cell (OHC) potassium current, I(K,n), a current distinguished by an activation curve shifted to exceptionally negative potentials.	Potassium	4-13	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	22-27
15707997-1	2005	All five members of the KCNE beta-subunit family are capable of modulating the KCNQ1 potassium current.	Potassium	85-94	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	79-84
15757638-0	2005	ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.	Potassium	27-36	mitogen-activated protein kinase 3	Homo sapiens	0-6
15757638-0	2005	ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.	Potassium	27-36	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	79-83
15757638-0	2005	ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.	Potassium	27-36	mitogen-activated protein kinase 3	Homo sapiens	88-92
15757638-1	2005	We have recently reported that the ASK1-p38 MAPK pathway has an important role in the low potassium (LK)-induced apoptosis of cultured cerebellar granule neurons.	Potassium	90-99	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	35-39
15757638-1	2005	We have recently reported that the ASK1-p38 MAPK pathway has an important role in the low potassium (LK)-induced apoptosis of cultured cerebellar granule neurons.	Potassium	90-99	mitogen-activated protein kinase 1	Homo sapiens	40-43
15757638-2	2005	In the present study, we observed that ERK1/2 were significantly activated 6 h after a change of medium from HK (high potassium) to LK.	Potassium	118-127	mitogen-activated protein kinase 3	Homo sapiens	39-45
15757667-0	2005	Analysis of the mKir2.1 channel activity in potassium influx defective Saccharomyces cerevisiae strains determined as changes in growth characteristics.	Potassium	44-53	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	16-23
15772344-2	2005	We demonstrated previously that the late and sustained ERK activation in cerebellar granule neurons (CGNs) cultured in low potassium predominantly promotes plasma membrane (PM) damage.	Potassium	123-132	mitogen-activated protein kinase 1	Homo sapiens	55-58
15731462-2	2005	Genetic mutations in the alpha- (KCNQ1) and beta- (KCNE1) subunits of I(Ks) underlie Long QT Syndrome type 1 and 5 (LQT-1 and LQT-5), respectively, and predispose carriers to the development of polymorphic ventricular arrhythmias and sudden cardiac death.	Potassium	72-74	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	33-38
15731462-2	2005	Genetic mutations in the alpha- (KCNQ1) and beta- (KCNE1) subunits of I(Ks) underlie Long QT Syndrome type 1 and 5 (LQT-1 and LQT-5), respectively, and predispose carriers to the development of polymorphic ventricular arrhythmias and sudden cardiac death.	Potassium	72-74	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	51-56
15731462-6	2005	We reconstituted I(Ks) in CHO cells (ie, KCNQ1 coexpressed with KCNE1 and the adaptator protein Yotiao) and quantitatively examined the effects of beta-adrenergic stimulation on channel kinetics.	Potassium	19-21	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	41-46
15649626-2	2005	Lolitrem B potently inhibited hSlo potassium currents activated by depolarising voltage pulses in the presence of 10 microM free calcium.	Potassium	35-44	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	30-34
15865076-8	2005	Increases in the serum electrolytes potassium, magnesium and phosphate correlated positively with increases in free PSA.	Potassium	36-45	kallikrein related peptidase 3	Homo sapiens	116-119
15757667-1	2005	Potassium uptake defective Saccharomyces cerevisiae strains (Deltatrk1,2 and Deltatrk1,2 Deltatok1) were used for the phenotypic analysis of the mouse inward rectifying Kir2.1 channel by growth analysis.	Potassium	0-9	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	169-175
15757667-2	2005	Functional expression of both, multi-copy plasmid and chromosomally expressed GFP-mKir2.1 fusion constructs complemented the potassium uptake deficient phenotype in a pHout dependent manner.	Potassium	125-134	potassium inwardly-rectifying channel, subfamily J, member 2	Mus musculus	82-89
15900896-2	2005	The milk from cows infected with subclinical mastitis revealed a significant decrease in potassium (P &lt; 0.001) and a significant increase in sodium and phosphorus content (P &lt; 0.01).	Potassium	89-98	Weaning weight-maternal milk	Bos taurus	4-8
15846098-2	2005	Human ether-a-go-go-related gene (HERG) encoding one of the components of delayed rectifier potassium currents has been indicated to be involved in tumor cell growth and death.	Potassium	92-101	potassium voltage-gated channel subfamily H member 2	Homo sapiens	34-38
15818545-0	2005	Serum potassium and acid-base parameters in severe dialysis-associated hyperglycemia treated with insulin therapy.	Potassium	6-15	insulin	Homo sapiens	98-105
15726306-1	2005	Hypokalemic periodic paralysis (HypoPP) is an autosomal dominant disorder which is characterized by periodic attacks of muscle weakness associated with a decrease in the serum potassium level.	Potassium	176-185	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	32-38
15900896-5	2005	Comparison of healthy cow"s milk with that of clinically mastitic milk showed a highly significant decrease in levels of calcium, magnesium (P &lt; 0.001) and potassium (P &lt; 0.01).	Potassium	159-168	Weaning weight-maternal milk	Bos taurus	28-32
15900896-7	2005	Comparison of macro-minerals in milk from cows with subclinical and clinical mastitis revealed a significant decrease in potassium contents (P &lt; 0.05) compared with that of healthy cows.	Potassium	121-130	Weaning weight-maternal milk	Bos taurus	32-36
15938039-3	2005	These include the stimulation of the renin-angiotensin-aldosterone system with the attending negative cardiovascular effects that ensue from this activation and several metabolic alterations, namely those in glucose, lipid, and potassium metabolism.	Potassium	228-237	renin	Homo sapiens	37-42
15525794-5	2005	In contrast to sympathetic neurons, MLK inhibitors maintain only short-term survival of potassium- and serum-deprived rat cerebellar granule neurons (CGNs), despite continuous inhibition of the JNK pathway.	Potassium	88-97	mitogen activated protein kinase kinase kinase 12	Rattus norvegicus	36-39
15900896-3	2005	Similarly, the milk from cows with the clinical form of the disease showed a significant increase in sodium (P &lt; 0.001) and a significant decrease in potassium, magnesium (P &lt; 0.001) and calcium (P &lt; 0.01).	Potassium	153-162	Weaning weight-maternal milk	Bos taurus	15-19
15644200-0	2005	Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures.	Potassium	64-73	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	0-4
15671864-5	2005	BDNF levels were decreased by 45-65% in the presence of TTX or receptor antagonists and increased by 25% in elevated extracellular potassium.	Potassium	131-140	brain-derived neurotrophic factor	Rattus norvegicus	0-4
15721243-5	2005	Hyperpolarization onsets were regeneratively amplified by a potassium current (KIR) whose activation promoted further hyperpolarization.	Potassium	60-69	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	79-82
15694920-12	2005	Pressure application of 4-aminopyridine, a blocker of the transient potassium current, onto angiotensin II-sensitive neurons increased their firing rate and the increase of unit firing rate was almost the same in WKY and SHR.	Potassium	68-77	angiotensinogen	Rattus norvegicus	92-106
15365776-9	2005	Thus, the antigen-processing and antigen-presentation capacity of KS cells was further demonstrated by the stimulation of HER-2/neu-specific CD8+ T cells in PBMCs of breast cancer patients in vitro.	Potassium	66-68	erb-b2 receptor tyrosine kinase 2	Homo sapiens	122-127
15680342-4	2005	In CA1 neurons, the amplitude of rapid inactivating potassium currents (I(A)) was significantly increased at 14 h and returned to control levels at 38 h after ischemia; the rising slope and decay time constant of I(A) were accordingly increased after ischemia.	Potassium	52-61	carbonic anhydrase 1	Homo sapiens	3-6
15680342-8	2005	The amplitudes of delayed rectifier potassium currents (I(Kd)) in CA1 neurons were progressively increased after ischemia.	Potassium	36-45	carbonic anhydrase 1	Homo sapiens	66-69
15365776-9	2005	Thus, the antigen-processing and antigen-presentation capacity of KS cells was further demonstrated by the stimulation of HER-2/neu-specific CD8+ T cells in PBMCs of breast cancer patients in vitro.	Potassium	66-68	erb-b2 receptor tyrosine kinase 2	Homo sapiens	128-131
15243721-1	2005	We characterized the effects of intracellular Mg(2+) (Mg(2+) (i)) on potassium currents mediated by the Kv1.5 and Kv2.1 channels expressed in Xenopus oocytes.	Potassium	69-78	potassium voltage-gated channel subfamily A member 4 L homeolog	Xenopus laevis	104-109
15243721-1	2005	We characterized the effects of intracellular Mg(2+) (Mg(2+) (i)) on potassium currents mediated by the Kv1.5 and Kv2.1 channels expressed in Xenopus oocytes.	Potassium	69-78	potassium channel, voltage gated Shab related subfamily B, member 1 S homeolog	Xenopus laevis	114-119
15662077-1	2005	A 67 year old woman developed acute renal failure with serum potassium 9.4 mmol/l requiring emergency dialysis after seven days of diarrhoea while taking an ACE inhibitor for vascular disease.	Potassium	61-70	angiotensin I converting enzyme	Homo sapiens	157-160
15733107-9	2005	The decrease in ACL activity was inversely correlated with an increase in urinary excretion of both potassium (r = -0.620, P &lt; 0.0001) and citrate (r = -0.451, P &lt; 0.004).	Potassium	100-109	ATP citrate lyase	Homo sapiens	16-19
15621334-0	2005	Effects of sodium metabisulfite on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus.	Potassium	35-44	carbonic anhydrase 1	Rattus norvegicus	74-77
15621334-1	2005	The effects of sodium metabisulfite (SMB), a food preservative mostly used in food and drug industries, on voltage-dependent potassium currents in acutely isolated hippocampal CA1 pyramidal neurons of rat were studied using the whole-cell patch-clamp techniques.	Potassium	125-134	carbonic anhydrase 1	Rattus norvegicus	176-179
15667321-5	2005	Using a selection system in which potassium uptake was made dependent on amino acid signalling, our laboratory has obtained and described gain-of-function mutations in SSY1.	Potassium	34-43	Ssy1p	Saccharomyces cerevisiae S288C	168-172
15653788-7	2005	The PGE2-induced increase in membrane excitability seemed to result from its inhibition of the potassium currents, which in turn, boosted dendritic Ca2+ influx during dendritic-depolarizing current injections.	Potassium	95-104	carbonic anhydrase 2	Rattus norvegicus	148-151
15627496-7	2005	Injection of VIP into the nucleus tractus solitarius increased jejunal potassium absorption.	Potassium	71-80	vasoactive intestinal peptide	Rattus norvegicus	13-16
15627496-8	2005	Moreover, VIP associated with vagotomy resulted in inhibition of jejunal potassium absorption by VIP alone at 40 min after perfusion (5.99 +/- 0.74 vs. 9.83 +/- 0.57 microM).	Potassium	73-82	vasoactive intestinal peptide	Rattus norvegicus	10-13
15627496-8	2005	Moreover, VIP associated with vagotomy resulted in inhibition of jejunal potassium absorption by VIP alone at 40 min after perfusion (5.99 +/- 0.74 vs. 9.83 +/- 0.57 microM).	Potassium	73-82	vasoactive intestinal peptide	Rattus norvegicus	97-100
15627496-10	2005	VIP had a modulatory action on jejunal potassium absorption when injected into the nucleus tractus solitarius.	Potassium	39-48	vasoactive intestinal peptide	Rattus norvegicus	0-3
15661075-12	2005	Patients with the variant alleles showed an increased urinary potassium excretion rate in relation to their renin levels.	Potassium	62-71	renin	Homo sapiens	108-113
15702350-7	2005	ET-1 modulated I(Ks) biphasically: a transient increase followed by a decrease.	Potassium	17-19	endothelin 1	Homo sapiens	0-4
15702350-10	2005	When I(Ks) was increased by 10(-6) M isoproterenol (ISO), ET-1 did not increase but rather decreased the current to an even greater extent than under control conditions.	Potassium	7-9	endothelin 1	Homo sapiens	58-62
15698834-3	2005	KCNE1 associates with KCNQ1 in vitro to generate a potassium current closely resembling the slowly activating delayed rectifier (I(Ks)).	Potassium	51-60	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	0-5
15698834-3	2005	KCNE1 associates with KCNQ1 in vitro to generate a potassium current closely resembling the slowly activating delayed rectifier (I(Ks)).	Potassium	51-60	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	22-27
15698834-3	2005	KCNE1 associates with KCNQ1 in vitro to generate a potassium current closely resembling the slowly activating delayed rectifier (I(Ks)).	Potassium	131-133	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	0-5
15698834-3	2005	KCNE1 associates with KCNQ1 in vitro to generate a potassium current closely resembling the slowly activating delayed rectifier (I(Ks)).	Potassium	131-133	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	22-27
15698834-10	2005	Even in the presence of additional KCNE1, KCNE4 and KCNE5 exert dominant effects on I(Ks).	Potassium	86-88	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	35-40
15698834-10	2005	Even in the presence of additional KCNE1, KCNE4 and KCNE5 exert dominant effects on I(Ks).	Potassium	86-88	potassium voltage-gated channel subfamily E regulatory subunit 4	Homo sapiens	42-47
15698834-10	2005	Even in the presence of additional KCNE1, KCNE4 and KCNE5 exert dominant effects on I(Ks).	Potassium	86-88	potassium voltage-gated channel subfamily E regulatory subunit 5	Homo sapiens	52-57
16492552-8	2005	Amylin had a transient effect to lower plasma potassium concentration.	Potassium	46-55	islet amyloid polypeptide	Rattus norvegicus	0-6
15692183-4	2005	The expression of SEN1 gene in leaves was enhanced under nutrition stress (nitrogen, phosphate, and potassium starvation), but the expression of SEN1 gene in roots was induced only by phosphate starvation.	Potassium	100-109	splicing endonuclease 1	Arabidopsis thaliana	18-22
15569827-5	2005	I(Ks) enhancement induced by A23187 was attributable to actions of nitric oxide (NO), because they were inhibited by an inhibitor of NO synthase (NOS) and by a NO scavenger.	Potassium	2-4	nitric oxide synthase, inducible	Cavia porcellus	133-144
15569827-6	2005	A23187-induced alterations of APD and I(Ks) were strongly suppressed by a NOS3 inhibitor, but barely affected by a NOS1 inhibitor, suggesting that NOS3 was responsible for NO release in this phenomenon.	Potassium	40-42	nitric oxide synthase, endothelial	Cavia porcellus	74-78
15569827-6	2005	A23187-induced alterations of APD and I(Ks) were strongly suppressed by a NOS3 inhibitor, but barely affected by a NOS1 inhibitor, suggesting that NOS3 was responsible for NO release in this phenomenon.	Potassium	40-42	nitric oxide synthase, endothelial	Cavia porcellus	147-151
15569827-8	2005	Thus, CaM-dependent NOS3 activation confers the selective Ca2+-sensitivity on I(Ks).	Potassium	80-82	nitric oxide synthase, endothelial	Cavia porcellus	20-24
15350194-8	2005	Specifically, RTN3A1 expression was down-regulated upon cell death of cerebellar granule neurons triggered by potassium deprivation.	Potassium	110-119	reticulon 3	Homo sapiens	14-20
15590995-0	2005	Role of Sgk1 in salt and potassium homeostasis.	Potassium	25-34	serum/glucocorticoid regulated kinase 1	Homo sapiens	8-12
15639021-10	2005	They have shown that, in the renal distal tubule, WNK4 inhibits sodium reabsorption and potassium secretion, via inhibition of NCC (thiazide-sensitive Na+-Cl- cotransporter) and K+ channel ROMK activity, respectively.	Potassium	88-97	serine/threonine-protein kinase WNK4	Canis lupus familiaris	50-54
15650548-6	2005	When 0.4 IU/ml thrombin was used in samples provided by 10 healthy individuals treated with acetysalicylic acid, Ks levels were increased during versus before therapy.	Potassium	113-115	coagulation factor II, thrombin	Homo sapiens	15-23
16363886-20	2005	Regular review of cardiovascular status (and monitoring of serum potassium concentration) in patients taking beta(2)-adrenoceptor agonists is crucial.	Potassium	65-74	adrenoceptor beta 2	Homo sapiens	109-129
15716081-0	2005	Effects of the antiepileptic drugs lamotrigine, topiramate and gabapentin on hERG potassium currents.	Potassium	82-91	ETS transcription factor ERG	Homo sapiens	77-81
15668496-9	2005	IGF-I was positively associated with intakes of protein, magnesium, zinc, calcium, potassium, and phosphorus, and IGFBP-3 was positively associated with energy.	Potassium	83-92	insulin like growth factor 1	Homo sapiens	0-5
16276080-6	2005	Glucose-potassium-insulin infusion or adjusted insulin infusions each have their proponents: both are effective but both carry a small risk of hypoglycaemia.	Potassium	8-17	insulin	Homo sapiens	18-25
15968087-8	2005	Serum/potassium (S/K) deprivation induced apoptotic cell death mediated by the activation of several kinases such as glycogen synthase kinase-3beta and CDK5, as well as the breakdown of p35 in the neurotoxic fragment p25; inactivation of myocyte enhancer factor-2 (MEF2) was also found.	Potassium	6-15	glycogen synthase kinase 3 beta	Rattus norvegicus	117-147
15968087-8	2005	Serum/potassium (S/K) deprivation induced apoptotic cell death mediated by the activation of several kinases such as glycogen synthase kinase-3beta and CDK5, as well as the breakdown of p35 in the neurotoxic fragment p25; inactivation of myocyte enhancer factor-2 (MEF2) was also found.	Potassium	6-15	cyclin-dependent kinase 5	Rattus norvegicus	152-156
15968087-8	2005	Serum/potassium (S/K) deprivation induced apoptotic cell death mediated by the activation of several kinases such as glycogen synthase kinase-3beta and CDK5, as well as the breakdown of p35 in the neurotoxic fragment p25; inactivation of myocyte enhancer factor-2 (MEF2) was also found.	Potassium	6-15	cyclin-dependent kinase 5 regulatory subunit 1	Rattus norvegicus	186-189
15968087-8	2005	Serum/potassium (S/K) deprivation induced apoptotic cell death mediated by the activation of several kinases such as glycogen synthase kinase-3beta and CDK5, as well as the breakdown of p35 in the neurotoxic fragment p25; inactivation of myocyte enhancer factor-2 (MEF2) was also found.	Potassium	6-15	lipocalin 2	Rattus norvegicus	217-220
16019148-4	2005	Interestingly, we found that the protective effects of pituitary adenylate cyclase activating polypeptide were related to the absence of a 4-aminopyridine (IC50=144 microM) sensitive rapidly inactivating potassium current often referred to as A-type current.	Potassium	204-213	adenylate cyclase activating polypeptide 1	Mus musculus	55-105
15610242-5	2005	METHODS: To assess the activation state of the CaSR, we developed a new method based on the functional coupling between CaSR activity and gating of calcium sensitive potassium currents mediated by SK4 potassium channels.	Potassium	166-175	calcium-sensing receptor	Rattus norvegicus	47-51
15610242-5	2005	METHODS: To assess the activation state of the CaSR, we developed a new method based on the functional coupling between CaSR activity and gating of calcium sensitive potassium currents mediated by SK4 potassium channels.	Potassium	166-175	calcium-sensing receptor	Rattus norvegicus	120-124
15610242-5	2005	METHODS: To assess the activation state of the CaSR, we developed a new method based on the functional coupling between CaSR activity and gating of calcium sensitive potassium currents mediated by SK4 potassium channels.	Potassium	166-175	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	197-200
15610242-7	2005	RESULTS: Coexpression of CaSR and SK4 gave rise to potassium currents that were dependent on CaSR-mediated intracellular calcium release, and thereby corresponded to the activation state of the CaSR.	Potassium	51-60	calcium-sensing receptor	Rattus norvegicus	25-29
15610242-7	2005	RESULTS: Coexpression of CaSR and SK4 gave rise to potassium currents that were dependent on CaSR-mediated intracellular calcium release, and thereby corresponded to the activation state of the CaSR.	Potassium	51-60	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	34-37
15610242-7	2005	RESULTS: Coexpression of CaSR and SK4 gave rise to potassium currents that were dependent on CaSR-mediated intracellular calcium release, and thereby corresponded to the activation state of the CaSR.	Potassium	51-60	calcium-sensing receptor	Rattus norvegicus	93-97
15610242-7	2005	RESULTS: Coexpression of CaSR and SK4 gave rise to potassium currents that were dependent on CaSR-mediated intracellular calcium release, and thereby corresponded to the activation state of the CaSR.	Potassium	51-60	calcium-sensing receptor	Rattus norvegicus	93-97
15664687-5	2005	In voltage clamp experiments NT decreased an outward current (from 488 +/- 161 to 340 +/- 96 pA at +40 mV; n = 5) which reversed near the potassium equilibrium potential.	Potassium	138-147	neurotensin	Rattus norvegicus	29-31
16203097-0	2005	Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning.	Potassium	176-185	gap junction protein, gamma 2	Rattus norvegicus	0-11
16050264-2	2005	The voltage-gated potassium channel formed by hERG pore-forming alpha subunits generates the IKr cardiac potassium current, and is considered essential for human ventricular repolarization.	Potassium	18-27	ETS transcription factor ERG	Homo sapiens	46-50
15664687-8	2005	Our results suggest that NTR1 receptors can modulate post-synaptic responses in neurons of the subpostremal NTS by increasing cell excitability as a result of blockade of a potassium conductance.	Potassium	173-182	neurotensin receptor 1	Rattus norvegicus	25-29
15671919-7	2004	Preserving cellular potassium and magnesium pools by blocking the aldosterone effects could also improve both cellular insulin action and insulin secretion.	Potassium	20-29	insulin	Homo sapiens	119-126
15581616-1	2004	The Ppz protein phosphatases have been recently shown to negatively regulate the major potassium transport system in the yeast Saccharomyces cerevisiae, encoded by the TRK1 and TRK2 genes.	Potassium	87-96	Trk1p	Saccharomyces cerevisiae S288C	168-172
15581616-1	2004	The Ppz protein phosphatases have been recently shown to negatively regulate the major potassium transport system in the yeast Saccharomyces cerevisiae, encoded by the TRK1 and TRK2 genes.	Potassium	87-96	Trk2p	Saccharomyces cerevisiae S288C	177-181
15581616-6	2004	Therefore, our results indicate that, in addition to their role in regulating Trk potassium transporters, Ppz phosphatases (essentially Ppz1), positively affect the residual low affinity potassium transport mechanisms in yeast.	Potassium	82-91	salt homeostasis regulator	Saccharomyces cerevisiae S288C	136-140
15583131-8	2004	Importantly, stable overexpression of KS-WNK1 significantly increases transepithelial Na(+) transport in cortical collecting duct cells.	Potassium	38-40	WNK lysine deficient protein kinase 1	Rattus norvegicus	41-45
15583131-9	2004	Similarly, coexpression of KS-WNK1 and the epithelial Na(+) channel in Fischer rat thyroid epithelial cells also stimulates Na(+) current, suggesting that KS-WNK1 affects the subcellular location or activity but not the expression of epithelial Na(+) channel.	Potassium	27-29	WNK lysine deficient protein kinase 1	Rattus norvegicus	30-34
15583131-9	2004	Similarly, coexpression of KS-WNK1 and the epithelial Na(+) channel in Fischer rat thyroid epithelial cells also stimulates Na(+) current, suggesting that KS-WNK1 affects the subcellular location or activity but not the expression of epithelial Na(+) channel.	Potassium	27-29	WNK lysine deficient protein kinase 1	Rattus norvegicus	158-162
15596759-0	2004	New mutations of SCN4A cause a potassium-sensitive normokalemic periodic paralysis.	Potassium	31-40	sodium voltage-gated channel alpha subunit 4	Homo sapiens	17-22
15596759-12	2004	CONCLUSION: A potassium-sensitive and normokalemic type of periodic paralysis caused by new SCN4A mutations at codon 675 is reported.	Potassium	14-23	sodium voltage-gated channel alpha subunit 4	Homo sapiens	92-97
15381257-4	2004	In patch-clamp experiments, we showed that TNFalpha and ceramide depolarise the RMP by inhibiting an acid-sensitive inwardly rectifying potassium current.	Potassium	136-145	tumor necrosis factor	Rattus norvegicus	43-51
15388777-2	2004	In rat beta cells transfected with green fluorescent protein-tagged PKC-alpha (PKC-alpha-EGFP), a depolarizing concentration of potassium induced transient elevation of cytoplasmic free calcium ([Ca(2)(+)](c)), which was accompanied by transient translocation of PKC-alpha-EGFP from the cytosol to the plasma membrane.	Potassium	128-137	protein kinase C, alpha	Rattus norvegicus	68-77
15365637-11	2004	In summary, cardiac repolarizing hERG/I(Kr) potassium currents are modulated by alpha(1A)-adrenoceptors via PKC and PKA independently of direct channel phosphorylation.	Potassium	44-53	ETS transcription factor ERG	Homo sapiens	33-37
15365637-11	2004	In summary, cardiac repolarizing hERG/I(Kr) potassium currents are modulated by alpha(1A)-adrenoceptors via PKC and PKA independently of direct channel phosphorylation.	Potassium	44-53	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	80-88
15319455-4	2004	Cellular excitation with high potassium potently stimulated endogenous GHRH gene 5"-promoter activity as well as the NFAT-mediated gene transcription, the former being further enhanced by coexpression of NFAT.	Potassium	30-39	growth hormone releasing hormone	Rattus norvegicus	71-75
15319455-4	2004	Cellular excitation with high potassium potently stimulated endogenous GHRH gene 5"-promoter activity as well as the NFAT-mediated gene transcription, the former being further enhanced by coexpression of NFAT.	Potassium	30-39	nuclear factor of activated T-cells 5	Rattus norvegicus	117-121
15319455-4	2004	Cellular excitation with high potassium potently stimulated endogenous GHRH gene 5"-promoter activity as well as the NFAT-mediated gene transcription, the former being further enhanced by coexpression of NFAT.	Potassium	30-39	nuclear factor of activated T-cells 5	Rattus norvegicus	204-208
15528278-2	2004	I(Ks), the slow heart potassium current, is carried by the I(Ks) potassium channel, a substrate for PKA phosphorylation in response to sympathetic nerve stimulation, is a macromolecular complex that includes the KCNQ1 alpha subunit, the KCNE1 regulatory subunit, and the AKAP Yotiao.	Potassium	2-4	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	237-242
15365637-0	2004	Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors.	Potassium	55-64	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	90-98
15388777-2	2004	In rat beta cells transfected with green fluorescent protein-tagged PKC-alpha (PKC-alpha-EGFP), a depolarizing concentration of potassium induced transient elevation of cytoplasmic free calcium ([Ca(2)(+)](c)), which was accompanied by transient translocation of PKC-alpha-EGFP from the cytosol to the plasma membrane.	Potassium	128-137	protein kinase C, alpha	Rattus norvegicus	79-93
15528278-2	2004	I(Ks), the slow heart potassium current, is carried by the I(Ks) potassium channel, a substrate for PKA phosphorylation in response to sympathetic nerve stimulation, is a macromolecular complex that includes the KCNQ1 alpha subunit, the KCNE1 regulatory subunit, and the AKAP Yotiao.	Potassium	2-4	A-kinase anchoring protein 1	Homo sapiens	271-275
15388777-2	2004	In rat beta cells transfected with green fluorescent protein-tagged PKC-alpha (PKC-alpha-EGFP), a depolarizing concentration of potassium induced transient elevation of cytoplasmic free calcium ([Ca(2)(+)](c)), which was accompanied by transient translocation of PKC-alpha-EGFP from the cytosol to the plasma membrane.	Potassium	128-137	protein kinase C, alpha	Rattus norvegicus	79-88
15528278-2	2004	I(Ks), the slow heart potassium current, is carried by the I(Ks) potassium channel, a substrate for PKA phosphorylation in response to sympathetic nerve stimulation, is a macromolecular complex that includes the KCNQ1 alpha subunit, the KCNE1 regulatory subunit, and the AKAP Yotiao.	Potassium	2-4	A-kinase anchoring protein 9	Homo sapiens	276-282
15388777-3	2004	Potassium also induced transient translocation of PKC-theta-EGFP, the C1 domain of PKC-gamma and PKC-epsilon-GFP.	Potassium	0-9	protein kinase C, gamma	Rattus norvegicus	83-92
15528278-2	2004	I(Ks), the slow heart potassium current, is carried by the I(Ks) potassium channel, a substrate for PKA phosphorylation in response to sympathetic nerve stimulation, is a macromolecular complex that includes the KCNQ1 alpha subunit, the KCNE1 regulatory subunit, and the AKAP Yotiao.	Potassium	22-31	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	237-242
15388777-7	2004	When islets were incubated for 10 min with high potassium, Go-6976, an inhibitor of conventional PKC, and PKC-alpha pseudosubstrate fused to antennapedia peptide (Antp-PKC(19-31)) increased potassium induced secretion.	Potassium	190-199	protein kinase C, alpha	Rattus norvegicus	106-115
15528278-2	2004	I(Ks), the slow heart potassium current, is carried by the I(Ks) potassium channel, a substrate for PKA phosphorylation in response to sympathetic nerve stimulation, is a macromolecular complex that includes the KCNQ1 alpha subunit, the KCNE1 regulatory subunit, and the AKAP Yotiao.	Potassium	22-31	A-kinase anchoring protein 1	Homo sapiens	271-275
15528278-2	2004	I(Ks), the slow heart potassium current, is carried by the I(Ks) potassium channel, a substrate for PKA phosphorylation in response to sympathetic nerve stimulation, is a macromolecular complex that includes the KCNQ1 alpha subunit, the KCNE1 regulatory subunit, and the AKAP Yotiao.	Potassium	22-31	A-kinase anchoring protein 9	Homo sapiens	276-282
15388777-11	2004	Taken together, PKC-alpha is activated when cells are depolarized by a high concentration of potassium or glucose.	Potassium	93-102	protein kinase C, alpha	Rattus norvegicus	16-25
15368194-5	2004	An arginine-to-cysteine mutation at position 27 (R27C) of KCNE2, the beta subunit of the KCNQ1-KCNE2 channel responsible for a background potassium current, was found in 2 of the 28 probands.	Potassium	138-147	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	58-63
15505206-7	2004	The features of AtTPK4 point toward a role in potassium homeostasis and membrane voltage control of the growing pollen tube.	Potassium	46-55	Outward rectifying potassium channel protein	Arabidopsis thaliana	16-22
15511625-7	2004	Co-expression of mutant (KCNQ1-P343S) and wild-type (KCNQ1) cRNA in Xenopus oocytes produced potassium currents reduced by approximately 92%, while IKs reconstitution experiments with a combination of KCNQ1 mutant, wild-type and KCNE1 subunits yielded currents reduced by approximately 60%.	Potassium	93-102	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	25-30
15511625-7	2004	Co-expression of mutant (KCNQ1-P343S) and wild-type (KCNQ1) cRNA in Xenopus oocytes produced potassium currents reduced by approximately 92%, while IKs reconstitution experiments with a combination of KCNQ1 mutant, wild-type and KCNE1 subunits yielded currents reduced by approximately 60%.	Potassium	93-102	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	53-58
15511625-7	2004	Co-expression of mutant (KCNQ1-P343S) and wild-type (KCNQ1) cRNA in Xenopus oocytes produced potassium currents reduced by approximately 92%, while IKs reconstitution experiments with a combination of KCNQ1 mutant, wild-type and KCNE1 subunits yielded currents reduced by approximately 60%.	Potassium	93-102	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	53-58
15368194-5	2004	An arginine-to-cysteine mutation at position 27 (R27C) of KCNE2, the beta subunit of the KCNQ1-KCNE2 channel responsible for a background potassium current, was found in 2 of the 28 probands.	Potassium	138-147	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	89-94
15368194-5	2004	An arginine-to-cysteine mutation at position 27 (R27C) of KCNE2, the beta subunit of the KCNQ1-KCNE2 channel responsible for a background potassium current, was found in 2 of the 28 probands.	Potassium	138-147	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	95-100
15573468-8	2004	We investigated the effects of DW-224a on the human ether-a-go-go-related gene (hERG) mediated potassium currents to evaluate its potential to induce QT interval prolongation.	Potassium	95-104	ETS transcription factor ERG	Homo sapiens	80-84
15374744-0	2004	Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.	Potassium	17-26	carbonic anhydrase 1	Rattus norvegicus	142-145
15509759-5	2004	We demonstrate that CRH dose-dependently increases the firing rate of LC neurons through a direct (TTX- and cadmium-insensitive) mechanism by decreasing a potassium conductance.	Potassium	155-164	corticotropin releasing hormone	Homo sapiens	20-23
15477595-7	2004	However, significant differences are observed in the length and structure of the loops surrounding the active site, including the presence of two potassium ions in HDAC8 structure, one of which interacts with key catalytic residues.	Potassium	146-155	histone deacetylase 8	Homo sapiens	164-169
15477595-8	2004	CD data suggest a direct role of potassium in the fold stabilization of HDAC8.	Potassium	33-42	histone deacetylase 8	Homo sapiens	72-77
15534596-8	2004	Oligodendrocytes, astrocytes, and NG2-glia all contact axons at nodes of Ranvier and respond to glutamate, ATP, and potassium released during axonal electrical activity.	Potassium	116-125	chondroitin sulfate proteoglycan 4	Homo sapiens	34-37
15345706-6	2004	Overexpression of dysbindin induced the expression of two pre-synaptic proteins, SNAP25 and synapsin I, and increased extracellular basal glutamate levels and release of glutamate evoked by high potassium.	Potassium	195-204	dystrobrevin binding protein 1	Homo sapiens	18-27
15500468-0	2004	Potassium carrier TRH1 is required for auxin transport in Arabidopsis roots.	Potassium	0-9	Potassium transporter family protein	Arabidopsis thaliana	18-22
15469924-1	2004	Apical expression of the large-conductance, calcium- and voltage-activated potassium (MaxiK) channel in the cortical collecting duct is responsible for flow-stimulated potassium secretion.	Potassium	75-84	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	86-91
15374745-8	2004	These results suggest that the early increase of GAL in the CA1 pyramidal cells may be associated with the reduction of the excitotoxic damage, that long-lasting enhanced expression of endogenous GAL at 12 h-2 days after ischemia may be associated with efflux of potassium ion into the extracellular space, and that GAL expression in microglia 4 days after ischemia may be associated with reduction of ischemic damage.	Potassium	263-272	galanin and GMAP prepropeptide	Homo sapiens	196-199
15374745-8	2004	These results suggest that the early increase of GAL in the CA1 pyramidal cells may be associated with the reduction of the excitotoxic damage, that long-lasting enhanced expression of endogenous GAL at 12 h-2 days after ischemia may be associated with efflux of potassium ion into the extracellular space, and that GAL expression in microglia 4 days after ischemia may be associated with reduction of ischemic damage.	Potassium	263-272	galanin and GMAP prepropeptide	Homo sapiens	196-199
15351694-5	2004	A dominant-negative mutant of dynamin or potassium depletion blocks ephrin-B1 endocytosis.	Potassium	41-50	ephrin B1	Homo sapiens	68-77
15470140-5	2004	NPY induced a current that was dependent on extracellular potassium, reversed near the potassium equilibrium potential, showed inward rectification, was blocked by extracellular barium, and was abolished by GDP-betaS in the recording pipette, consistent with a G-protein-activated inwardly rectifying K+ (GIRK) current.	Potassium	58-67	neuropeptide Y	Mus musculus	0-3
15470140-5	2004	NPY induced a current that was dependent on extracellular potassium, reversed near the potassium equilibrium potential, showed inward rectification, was blocked by extracellular barium, and was abolished by GDP-betaS in the recording pipette, consistent with a G-protein-activated inwardly rectifying K+ (GIRK) current.	Potassium	87-96	neuropeptide Y	Mus musculus	0-3
15163620-1	2004	Despite its key role in potassium homeostasis, transcriptional control of the H(+)-K(+)-ATPase alpha(2)-subunit (HKalpha(2)) gene in the collecting duct remains poorly characterized.	Potassium	24-33	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	113-123
15446858-1	2004	The first noncentrosymmetric potassium templated borogermanate, K(2)[Ge(B(4)O(9))].2H(2)O, has been solvothermally synthesized and characterized by IR, SEM, powder X-ray diffraction (PXRD), TGA, energy dispersive spectroscopy (EDS), single crystal X-ray diffraction, and second harmonic generation (SHG) activity, respectively.	Potassium	29-38	T-box transcription factor 1	Homo sapiens	190-193
15336961-5	2004	Calsenilin binds Kv channels and modulates potassium conductance, playing a role in long-term potentiation as well as in other important plastic pathways.	Potassium	43-52	potassium voltage-gated channel interacting protein 3	Homo sapiens	0-10
15384026-0	2004	Effects of an ACE inhibitor or angiotensin receptor blocker on potassium in CAPD patients.	Potassium	63-72	angiotensin I converting enzyme	Homo sapiens	14-17
15353211-7	2004	In animals with carrageenan-induced arthritis, both basal and potassium-evoked release of CCK-LI were significantly increased compared to controls.	Potassium	62-71	cholecystokinin	Rattus norvegicus	90-93
15353211-8	2004	HPLC analysis of dialysates from the ACC during potassium stimulation showed that the main part of the immunoreactive material was sulphated CCK-8.	Potassium	48-57	cholecystokinin	Rattus norvegicus	141-144
15284836-3	2004	During a 12:12 light-dark cycle, as compared to control CHO cells, the implantation of encapsulated hANP-producing CHO cells was associated with an increase in the net excretion of water, sodium and potassium, and with a reversal of the advanced circadian phases related to renovascular hypertension in 2K1C rats.	Potassium	199-208	natriuretic peptide A	Homo sapiens	100-104
15377640-9	2004	Additional experiments revealed that erythromycin caused a comparable type I spectral change when bound to CYP3A5 and CYP3A4 (Ks=48 microM and 52 microM, respectively).	Potassium	126-128	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	118-124
15464194-4	2004	Under these conditions, VIP maximally reduced coronary resistance by 54% at 7 x 10(-9) M. The potency of VIP for reducing coronary resistance in these hearts, however, decreased 16-fold (EC50=4.90 x 10(-9) M) while that of SNP remained unaltered (EC50=3.39 x 10(-6) M), compared with hearts perfused with higher levels of potassium (5.9 mM) and calcium (2.5 mM).	Potassium	322-331	vasoactive intestinal peptide	Rattus norvegicus	24-27
15464194-4	2004	Under these conditions, VIP maximally reduced coronary resistance by 54% at 7 x 10(-9) M. The potency of VIP for reducing coronary resistance in these hearts, however, decreased 16-fold (EC50=4.90 x 10(-9) M) while that of SNP remained unaltered (EC50=3.39 x 10(-6) M), compared with hearts perfused with higher levels of potassium (5.9 mM) and calcium (2.5 mM).	Potassium	322-331	vasoactive intestinal peptide	Rattus norvegicus	105-108
15464194-8	2004	In conclusion, VIP is a potent vasodilator in the coronary circulation of the rat and the role of VIP in the control of coronary vascular resistance depends on the circulating levels of potassium and calcium.	Potassium	186-195	vasoactive intestinal peptide	Rattus norvegicus	15-18
15549578-6	2004	In the case of ATP1A2 mutations, haplo-insufficiency of the gene has been hypothesised to result in abnormal potassium level regulation because of faulty Na/K exchange with subsequent depolarisation and increased liability to spreading depression, or/and in abnormal calcium levels because of the concomitant activation of the Na/Ca exchanger, with a mechanism therefore comparable to that at work in FHM1.	Potassium	109-118	ATPase Na+/K+ transporting subunit alpha 2	Homo sapiens	15-21
15464194-8	2004	In conclusion, VIP is a potent vasodilator in the coronary circulation of the rat and the role of VIP in the control of coronary vascular resistance depends on the circulating levels of potassium and calcium.	Potassium	186-195	vasoactive intestinal peptide	Rattus norvegicus	98-101
15337265-4	2004	In cerebellar granule neurons (CGNs), indirubin-3"-oxime blocked c-Jun phosphorylation induced by potassium withdrawal and prevented CGNs from apoptosis in a dose dependent manner.	Potassium	98-107	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	65-70
15334679-12	2004	After HGF transfection, the survival rate of hepatocytes poisoned by CCl(4) significantly increased (83% vs 61%, P&lt;0.05), and the leakage of intracellular alanine transaminase and potassium ions decreased (586 nkat/L vs 1 089 nkat/L, P&lt;0.01; and 5.59 mmol/L vs 6.02 mmol/L, P&lt;0.01 respectively).	Potassium	183-192	hepatocyte growth factor	Homo sapiens	6-9
15383672-4	2004	A recent study has revealed that ERK is a key apoptotic factor in potassium deprivation-induced neuronal cell death by showing that ERK inhibitors protect neurons from low potassium conditions, whereas constitutively activated ERK activates cell death.	Potassium	66-75	mitogen-activated protein kinase 1	Homo sapiens	33-36
15383672-4	2004	A recent study has revealed that ERK is a key apoptotic factor in potassium deprivation-induced neuronal cell death by showing that ERK inhibitors protect neurons from low potassium conditions, whereas constitutively activated ERK activates cell death.	Potassium	66-75	mitogen-activated protein kinase 1	Homo sapiens	132-135
15383672-4	2004	A recent study has revealed that ERK is a key apoptotic factor in potassium deprivation-induced neuronal cell death by showing that ERK inhibitors protect neurons from low potassium conditions, whereas constitutively activated ERK activates cell death.	Potassium	66-75	mitogen-activated protein kinase 1	Homo sapiens	132-135
15383672-4	2004	A recent study has revealed that ERK is a key apoptotic factor in potassium deprivation-induced neuronal cell death by showing that ERK inhibitors protect neurons from low potassium conditions, whereas constitutively activated ERK activates cell death.	Potassium	172-181	mitogen-activated protein kinase 1	Homo sapiens	33-36
15383672-4	2004	A recent study has revealed that ERK is a key apoptotic factor in potassium deprivation-induced neuronal cell death by showing that ERK inhibitors protect neurons from low potassium conditions, whereas constitutively activated ERK activates cell death.	Potassium	172-181	mitogen-activated protein kinase 1	Homo sapiens	132-135
15383672-4	2004	A recent study has revealed that ERK is a key apoptotic factor in potassium deprivation-induced neuronal cell death by showing that ERK inhibitors protect neurons from low potassium conditions, whereas constitutively activated ERK activates cell death.	Potassium	172-181	mitogen-activated protein kinase 1	Homo sapiens	132-135
15339389-0	2004	Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells.	Potassium	62-71	angiotensinogen	Rattus norvegicus	10-24
15339389-0	2004	Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells.	Potassium	62-71	cathepsin H	Mus musculus	101-105
15333402-5	2004	In the insulin-glucose-potassium (IGK) group (n = 7), an IV bolus of regular insulin (2 U/kg) was given, followed by a glucose infusion (2 mL/kg of 50% dextrose in water) for 30 min and a potassium infusion (1-2 mmol.	Potassium	23-32	insulin	Canis lupus familiaris	7-14
15469643-1	2004	The increase in fractional rate of protein synthesis (Ks) in the skeletal muscle of growing rats during the transition from fasted to fed state has been explained by the synergistic action of a rise in plasma insulin and branched-chain amino acids (BCAA).	Potassium	54-56	LOC105613195	Ovis aries	209-216
15469420-6	2004	The Ka/Ks ratio between the coding sequence of human CLCN5 and its mouse orthologue is much less than 1.	Potassium	7-9	chloride voltage-gated channel 5	Homo sapiens	53-58
15300163-8	2004	These findings can explain the observed physiological abnormalities in patients with pseudohypoaldosteronism type II, and support a model in which WNK4 is a molecular switch that can alter the balance between chloride ion reabsorption and potassium ion secretion.	Potassium	239-248	WNK lysine deficient protein kinase 4	Homo sapiens	147-151
15492885-1	2004	Studies of the electrophysiological response to acetylcholine (ACh) in mammalian outer hair cells (OHCs) are hindered by the presence of a large potassium current, I(K,n), most likely mediated by channels containing the KCNQ4 subunit.	Potassium	145-154	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	220-225
15234075-5	2004	These results imply that AlCl3 could affect the activation and inactivation courses of sodium current and potassium current of rat hippocampal CA1 neurons, which may contribute to damage of the central nervous system by aluminum.	Potassium	106-115	carbonic anhydrase 1	Rattus norvegicus	143-146
15339979-0	2004	Growth hormone-mediated janus associated kinase-signal transducers and activators of transcription signaling in the growth hormone-resistant potassium-deficient rat.	Potassium	141-150	gonadotropin releasing hormone receptor	Rattus norvegicus	0-14
15339979-0	2004	Growth hormone-mediated janus associated kinase-signal transducers and activators of transcription signaling in the growth hormone-resistant potassium-deficient rat.	Potassium	141-150	gonadotropin releasing hormone receptor	Rattus norvegicus	116-130
15497768-5	2004	In smooth muscle cells, H2S produced by cystathionine gamma-lyase enhances the outward flux of potassium by opening potassium channels, leading to hyperpolarization of membrane potential and smooth muscle relaxation.	Potassium	95-104	cystathionine gamma-lyase	Homo sapiens	40-65
15276477-1	2004	OBJECTIVE: The cardiac inwardly rectifying potassium current IK1 and its molecular correlates Kir2.1 and Kir2.2 play an important role in cardiac repolarisation and in the pathogenesis of hereditary long-QT syndrome (LQTS-7).	Potassium	43-52	IKAROS family zinc finger 1	Homo sapiens	61-64
15559785-1	2004	Using clamp method it had been shown that He-Ne laser irradiation of the snail neurons increases the amplitude of voltage-gated slow potassium currents in dose of 0.7 x 10(-4) (fluence 1.5 x 10(2) Wt/m2) and decreases it in dose 0.7 x 10(-3).	Potassium	133-142	snail family transcriptional repressor 1	Homo sapiens	73-78
15235086-0	2004	Muscarinic modulation of erg potassium current.	Potassium	29-38	ETS transcription factor ERG	Homo sapiens	25-28
15276477-1	2004	OBJECTIVE: The cardiac inwardly rectifying potassium current IK1 and its molecular correlates Kir2.1 and Kir2.2 play an important role in cardiac repolarisation and in the pathogenesis of hereditary long-QT syndrome (LQTS-7).	Potassium	43-52	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	94-100
15276477-1	2004	OBJECTIVE: The cardiac inwardly rectifying potassium current IK1 and its molecular correlates Kir2.1 and Kir2.2 play an important role in cardiac repolarisation and in the pathogenesis of hereditary long-QT syndrome (LQTS-7).	Potassium	43-52	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	105-111
15285036-1	2004	AIM: To investigate the effectiveness of insulin on decreasing serum potassium concentration during anhepatic stage of orthotopic liver transplantation.	Potassium	69-78	insulin	Homo sapiens	41-48
15285036-7	2004	CONCLUSION: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in insulin-stimulated uptake of potassium.	Potassium	123-132	insulin	Homo sapiens	91-98
15261098-6	2004	TREK-1 may subserve some neuroprotective function in afferent nerve fibers as well as play a role in endolymph potassium homeostasis.	Potassium	111-120	potassium channel, subfamily K, member 2	Mus musculus	0-6
15285036-7	2004	CONCLUSION: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in insulin-stimulated uptake of potassium.	Potassium	123-132	insulin	Homo sapiens	245-252
15285036-7	2004	CONCLUSION: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in insulin-stimulated uptake of potassium.	Potassium	274-283	insulin	Homo sapiens	91-98
15285036-7	2004	CONCLUSION: In patients undergoing orthotopic liver transplantation, the administration of insulin rapidly decreases serum potassium concentration even in the absence of the liver, suggesting an important contribution by extrahepatic tissues in insulin-stimulated uptake of potassium.	Potassium	274-283	insulin	Homo sapiens	245-252
15169846-0	2004	Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels.	Potassium	53-62	potassium voltage-gated channel subfamily H member 2	Homo sapiens	90-94
15276244-5	2004	In this report, pretreatment with the p75 blocking antibody completely prevents the NGF-induced increase in the number of action potentials evoked by a ramp of depolarizing current as well as the suppression of a delayed rectifier-type of potassium current(s) in these neurons.	Potassium	239-248	nerve growth factor receptor	Rattus norvegicus	38-41
15265812-9	2004	Somatostatin had a variable effect on the rate of spontaneous miniature IPSCs in normal external potassium solutions.	Potassium	97-106	somatostatin	Rattus norvegicus	0-12
15265812-10	2004	In high external potassium solutions, somatostatin reduced the rate of miniature IPSCs in all neurons, and this inhibition was abolished by addition of Cd(2+) (30 microm).	Potassium	17-26	somatostatin	Rattus norvegicus	38-50
15265812-12	2004	These results indicate that somatostatin acts via sst-2 receptors to directly inhibit a subpopulation of PAG neurons by activating a potassium conductance and inhibits GABA release within PAG via a presynaptic Ca(2+)-dependent mechanism.	Potassium	133-142	somatostatin	Rattus norvegicus	28-40
15212727-5	2004	In view of the potential for serious hyperkalemia with the use of aldosterone receptor blockers, it is essential to monitor serum potassium closely and to adjust the dose of aldosterone antagonists based on serum potassium levels.	Potassium	130-139	nuclear receptor subfamily 3 group C member 2	Homo sapiens	66-86
15212727-5	2004	In view of the potential for serious hyperkalemia with the use of aldosterone receptor blockers, it is essential to monitor serum potassium closely and to adjust the dose of aldosterone antagonists based on serum potassium levels.	Potassium	213-222	nuclear receptor subfamily 3 group C member 2	Homo sapiens	66-86
15241677-8	2004	Therefore, deafness associated with Cx26 mutations may not only depend on reduced potassium re-circulation in the inner ear.	Potassium	82-91	gap junction protein beta 2 L homeolog	Xenopus laevis	36-40
15558947-3	2004	The data indicate that the inhibition of hK1 by sodium, potassium, calcium and magnesium is linear competitive and that divalent cations are more potent inhibitors of hK1 than univalent cations.	Potassium	56-65	keratin 1	Homo sapiens	41-44
15253724-1	2004	BACKGROUND: Previous studies from our laboratory have shown that luminal perfusion with arginine vasopressin (AVP) stimulates distal tubule secretory potassium flux (JK) via V1 receptors (Am J Physiol 278:F809-F816, 2000).	Potassium	150-159	arginine vasopressin	Rattus norvegicus	97-108
15253724-1	2004	BACKGROUND: Previous studies from our laboratory have shown that luminal perfusion with arginine vasopressin (AVP) stimulates distal tubule secretory potassium flux (JK) via V1 receptors (Am J Physiol 278:F809-F816, 2000).	Potassium	150-159	arginine vasopressin	Rattus norvegicus	110-113
15571757-5	2004	Anosmin-1 has an obligate functional interaction with membrane associated heparan sulphate proteoglycans (HSPG) and FGFR-1 (KAL-2) whose mutations lead to the autosomal dominant form of KS (AKS).	Potassium	186-188	anosmin 1	Homo sapiens	0-9
15571757-5	2004	Anosmin-1 has an obligate functional interaction with membrane associated heparan sulphate proteoglycans (HSPG) and FGFR-1 (KAL-2) whose mutations lead to the autosomal dominant form of KS (AKS).	Potassium	186-188	syndecan 2	Homo sapiens	106-110
15571757-5	2004	Anosmin-1 has an obligate functional interaction with membrane associated heparan sulphate proteoglycans (HSPG) and FGFR-1 (KAL-2) whose mutations lead to the autosomal dominant form of KS (AKS).	Potassium	186-188	fibroblast growth factor receptor 1	Homo sapiens	116-122
15571757-5	2004	Anosmin-1 has an obligate functional interaction with membrane associated heparan sulphate proteoglycans (HSPG) and FGFR-1 (KAL-2) whose mutations lead to the autosomal dominant form of KS (AKS).	Potassium	186-188	fibroblast growth factor receptor 1	Homo sapiens	124-129
15197736-5	2004	In this study, we have demonstrated that expression of vasoactive intestinal polypeptide (VIP), a member of the same VIP/secretin/glucagon family as PACAP, was activated markedly by Ca(2+) influx through L-type voltage-dependent Ca(2+) channels (L-VDCCs), which could be induced under the depolarizing condition induced by high concentration of potassium (K(+)) in the medium.	Potassium	345-354	vasoactive intestinal polypeptide	Mus musculus	55-88
15198683-8	2004	Microdialysis studies in striatum showed that both amphetamine- and potassium-evoked dopamine release in GDNF recipients were significantly increased.	Potassium	68-77	glial cell derived neurotrophic factor	Rattus norvegicus	105-109
15197736-5	2004	In this study, we have demonstrated that expression of vasoactive intestinal polypeptide (VIP), a member of the same VIP/secretin/glucagon family as PACAP, was activated markedly by Ca(2+) influx through L-type voltage-dependent Ca(2+) channels (L-VDCCs), which could be induced under the depolarizing condition induced by high concentration of potassium (K(+)) in the medium.	Potassium	345-354	vasoactive intestinal polypeptide	Mus musculus	90-93
15197736-5	2004	In this study, we have demonstrated that expression of vasoactive intestinal polypeptide (VIP), a member of the same VIP/secretin/glucagon family as PACAP, was activated markedly by Ca(2+) influx through L-type voltage-dependent Ca(2+) channels (L-VDCCs), which could be induced under the depolarizing condition induced by high concentration of potassium (K(+)) in the medium.	Potassium	345-354	secretin	Mus musculus	121-129
15197736-5	2004	In this study, we have demonstrated that expression of vasoactive intestinal polypeptide (VIP), a member of the same VIP/secretin/glucagon family as PACAP, was activated markedly by Ca(2+) influx through L-type voltage-dependent Ca(2+) channels (L-VDCCs), which could be induced under the depolarizing condition induced by high concentration of potassium (K(+)) in the medium.	Potassium	345-354	adenylate cyclase activating polypeptide 1	Mus musculus	149-154
15173323-2	2004	Previously we have reported that the overexpression of an ATPase activity-deficient form of SKD1 (suppressor of potassium transport growth defect), SKD1(E235Q), leads the perturbation of membrane transport through endosomes and lysosomes, however, the molecular mechanism behind the action of SKD1 is poorly understood.	Potassium	112-121	vacuolar protein sorting 4 homolog A	Homo sapiens	92-96
15158164-0	2004	Substance P inhibits potassium and calcium currents in inner ear spiral ganglion neurons.	Potassium	21-30	tachykinin 1	Mus musculus	0-11
15173323-2	2004	Previously we have reported that the overexpression of an ATPase activity-deficient form of SKD1 (suppressor of potassium transport growth defect), SKD1(E235Q), leads the perturbation of membrane transport through endosomes and lysosomes, however, the molecular mechanism behind the action of SKD1 is poorly understood.	Potassium	112-121	vacuolar protein sorting 4 homolog A	Homo sapiens	148-152
15173323-2	2004	Previously we have reported that the overexpression of an ATPase activity-deficient form of SKD1 (suppressor of potassium transport growth defect), SKD1(E235Q), leads the perturbation of membrane transport through endosomes and lysosomes, however, the molecular mechanism behind the action of SKD1 is poorly understood.	Potassium	112-121	vacuolar protein sorting 4 homolog A	Homo sapiens	148-152
15107477-0	2004	Novel KChIP2 isoforms increase functional diversity of transient outward potassium currents.	Potassium	73-82	potassium voltage-gated channel interacting protein 2	Homo sapiens	6-12
15180798-7	2004	During low-salt conditions, oxytocin reduced sodium and potassium excretion (11 +/- 2--4 +/- 2 and 93 +/- 19--42 +/- 3 micromol min(-1), respectively).	Potassium	56-65	oxytocin/neurophysin I prepropeptide	Homo sapiens	28-36
15159579-2	2004	An extremely thermostable acylphosphatase from a hyperthermophilic archaea, Pyrococcus horikoshii OT3, has been cloned, expressed in Escherichia coli, purified and crystallized using the sitting-drop vapour-diffusion method with potassium/sodium tartrate as the precipitant at pH 5.5.	Potassium	229-239	acylphosphatase	Pyrococcus horikoshii OT3	26-41
15189956-9	2004	A single dose of beta(2)-agonist increased the heart rate by 9.12 beats/min (95% confidence interval [CI], 5.32 to 12.92) and reduced the potassium concentration by 0.36 mmol/L (95% CI, 0.18 to 0.54), compared to placebo.	Potassium	138-147	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	17-23
15148258-3	2004	Since blockade of cardiac human ether-a-go-go-related gene (HERG) potassium currents is an important cause of acquired LQTS, we investigated the acute effects of amsacrine on cloned HERG channels to determine the electrophysiological basis for its proarrhythmic potential.	Potassium	66-75	potassium voltage-gated channel subfamily H member 2	Homo sapiens	60-64
15148258-4	2004	2 HERG channels were heterologously expressed in human HEK 293 cells and Xenopus laevis oocytes, and the respective potassium currents were recorded using patch-clamp and two-microelectrode voltage-clamp electrophysiology.	Potassium	116-125	potassium voltage-gated channel subfamily H member 2	Homo sapiens	2-6
15198689-1	2004	Deletion studies in transgenic mice indicate that the potassium inward rectifying channel Kir4.1 is crucial for oligodendrocyte differentiation and has a special role in regulation of extracellular potassium (K(+)), a major function of astrocytes.	Potassium	54-63	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	90-96
15153570-9	2004	The finding of a hyperinsulinemic response in acute metabolic acidosis suggests that an insulin response counterregulates any acidemia-induced cellular potassium efflux, resulting in stable plasma potassium concentrations.	Potassium	152-161	insulin	Homo sapiens	22-29
15153570-9	2004	The finding of a hyperinsulinemic response in acute metabolic acidosis suggests that an insulin response counterregulates any acidemia-induced cellular potassium efflux, resulting in stable plasma potassium concentrations.	Potassium	197-206	insulin	Homo sapiens	22-29
15159330-7	2004	Functional studies of the KvLQT1 V307L mutant (alone or coexpressed with the wild-type channel, in the presence of IsK) revealed a pronounced shift of the half-activation potential and an acceleration of the activation kinetics leading to a gain of function in I(Ks).	Potassium	263-265	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	26-32
15261303-4	2004	Stimulating the transformed cells with potassium and cAMP freed CYP11B2 from the mutant-caused transcriptional inhibition, whereas the transformation abolished induction of CYP17 by both stimulants.	Potassium	39-48	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	64-71
15261303-6	2004	The relief of CYP11B2 repression following the potassium and cAMP stimulation removed the restraint the mutant exerted on aldosterone synthesis, and resulted in aldosterone overproduction in the stimulated transformed cells.	Potassium	47-56	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	14-21
15261303-8	2004	Inhibition of SF-1 activity significantly decreased basal expression of ACTH receptor and its induction by potassium and cAMP.	Potassium	107-116	splicing factor 1	Homo sapiens	14-18
15261303-8	2004	Inhibition of SF-1 activity significantly decreased basal expression of ACTH receptor and its induction by potassium and cAMP.	Potassium	107-116	melanocortin 2 receptor	Homo sapiens	72-85
15120602-6	2004	However, the prenatally cocaine-treated pups showed significantly less BDNF release following high potassium depolarization than the saline-treated animals did in both these regions.	Potassium	99-108	brain-derived neurotrophic factor	Rattus norvegicus	71-75
15020588-6	2004	Agonists of the cAMP pathway, the beta-adrenergic agonist isoproterenol, and the neuropeptide vasoactive intestinal peptide activate CFTR-dependent transport from cells maintained in a high but not low extracellular potassium-rich saline, suggesting that depolarization of smooth muscle is critical to CFTR activation.	Potassium	216-225	CF transmembrane conductance regulator	Rattus norvegicus	133-137
15123736-1	2004	Our recent studies have shown that extracellular-regulated protein kinase (ERK) promotes cell death in cerebellar granule neurons (CGN) cultured in low potassium.	Potassium	152-161	mitogen-activated protein kinase 1	Homo sapiens	35-73
15122920-7	2004	Both wt and A30P alpha-synuclein caused rapid decrease in levels of intracellular potassium, followed by mitochondrial damage and cytochrome c leakage, with decreased cellular metabolism as compared to cells expressing A53T or hDAT alone.	Potassium	82-91	synuclein alpha	Homo sapiens	17-32
15123736-1	2004	Our recent studies have shown that extracellular-regulated protein kinase (ERK) promotes cell death in cerebellar granule neurons (CGN) cultured in low potassium.	Potassium	152-161	mitogen-activated protein kinase 1	Homo sapiens	75-78
15172012-5	2004	This includes (1) testing for blockade of I(Kr) or hERG-mediated potassium current in heterologous cell systems, (2) measurement of effects on the myocardial action potential in vitro; and (3) assessment of effects on the ECG in a well-conducted in vivo study.	Potassium	65-74	ETS transcription factor ERG	Homo sapiens	51-55
15066048-0	2004	Melatonin inhibits outward delayed rectifier potassium currents in hippocampal CA1 pyramidal neuron via intracellular indole-related domains.	Potassium	45-54	carbonic anhydrase 1	Rattus norvegicus	79-82
15216494-6	2004	However, increasing potassium intake should be restricted in patients with glomerular filtration rate (GFR) less than 60 mL/min/1.73 m(2).	Potassium	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
15130121-7	2004	Potassium permanganate reactivity shows that the two structure elements are not equivalent: with AsiA, the motA UP element-deleted promoter opens more slowly whereas the motA TC promoter opens like the wild type.	Potassium	0-9	flagellar motor protein MotA	Escherichia phage T4	107-111
15047028-6	2004	Noradrenaline overflow increased similarly to potassium depolarisation in vehicle and STZ-diabetic rats, whereas diabetic rats showed a significantly increased NPY overflow response to potassium depolarisation compared to vehicle rats.	Potassium	185-194	neuropeptide Y	Rattus norvegicus	160-163
14759559-0	2004	Internalization of neuropeptide Y Y1 and Y5 and of pancreatic polypeptide Y4 receptors is inhibited by lithium in preference to sodium and potassium ions.	Potassium	139-148	RNA, Ro60-associated Y5	Homo sapiens	19-43
15071113-0	2004	Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents.	Potassium	106-115	calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog	Xenopus laevis	0-38
14656937-9	2004	Co-localization studies established that the mitochondria are a primary site for 3-nitrotyrosine localization and immunoprecipitation/immunoblotting experiments confirmed that MnSOD tyrosine nitration occurs in AIDS-KS cells.	Potassium	216-218	superoxide dismutase 2	Homo sapiens	176-181
15084216-1	2004	Andersen"s Syndrome is a rare disease, hereditary with autosomal dominant transmission, of the ion channels of the sarcolemmal membranes of the cardiac and skeletal muscles (channelopathy), which affects chromosome 17 of the KCNJ2 gene, responsible for encoding the outward potassium delayed rectifier current KIR2.1, resulting in a loss or suppression of the function of this channel.	Potassium	274-283	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	225-230
15084216-1	2004	Andersen"s Syndrome is a rare disease, hereditary with autosomal dominant transmission, of the ion channels of the sarcolemmal membranes of the cardiac and skeletal muscles (channelopathy), which affects chromosome 17 of the KCNJ2 gene, responsible for encoding the outward potassium delayed rectifier current KIR2.1, resulting in a loss or suppression of the function of this channel.	Potassium	274-283	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	310-316
15041655-0	2004	Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels.	Potassium	0-9	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	41-47
15041655-0	2004	Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels.	Potassium	0-9	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	49-53
14656937-10	2004	Functional SOD assays showed that AIDS-KS cells possess significantly lower MnSOD activity relative to matched control cells; findings which correspond with ongoing MnSOD tyrosine nitration and subsequent inactivation within AIDS-KS cells.	Potassium	39-41	superoxide dismutase 2	Homo sapiens	11-14
14656937-10	2004	Functional SOD assays showed that AIDS-KS cells possess significantly lower MnSOD activity relative to matched control cells; findings which correspond with ongoing MnSOD tyrosine nitration and subsequent inactivation within AIDS-KS cells.	Potassium	39-41	superoxide dismutase 2	Homo sapiens	76-81
14656937-10	2004	Functional SOD assays showed that AIDS-KS cells possess significantly lower MnSOD activity relative to matched control cells; findings which correspond with ongoing MnSOD tyrosine nitration and subsequent inactivation within AIDS-KS cells.	Potassium	39-41	superoxide dismutase 2	Homo sapiens	165-170
15216418-1	2004	The TRK proteins-Trk1p and Trk2p- are the main agents responsible for "active" accumulation of potassium by the yeast Saccharomyces cerevisiae.	Potassium	95-104	Trk1p	Saccharomyces cerevisiae S288C	17-22
15023555-0	2004	Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current.	Potassium	106-115	angiotensinogen	Rattus norvegicus	15-29
15216418-1	2004	The TRK proteins-Trk1p and Trk2p- are the main agents responsible for "active" accumulation of potassium by the yeast Saccharomyces cerevisiae.	Potassium	95-104	Trk2p	Saccharomyces cerevisiae S288C	27-32
15051858-6	2004	Various side effects are associated with the use of ACE inhibitory drugs in the control of blood pressure including hypotension, increased potassium levels, reduced renal function, cough, angioedema, skin rashes, and fetal abnormalities.	Potassium	139-148	angiotensin I converting enzyme	Homo sapiens	52-55
14660513-1	2004	Exposure to prolonged bed rest is known to induce changes in the renin-angiotensin-aldosterone system (RAAS) by way of posture, sodium and potassium balance, and stress, which may have serious consequences for patients.	Potassium	139-148	renin	Homo sapiens	65-70
14992578-8	2004	In addition, several monovalent cation binding sites are identified, and a mechanism of activation of Kex2 by potassium ion is proposed.	Potassium	110-119	kexin KEX2	Saccharomyces cerevisiae S288C	102-106
15134796-3	2004	Potassium-induced cytoplasmic Ca2+ signal activates adenylyl cyclase; induces and activates StAR, the protein that carries cholesterol to the inner mitochondrial membrane and also enhances the expression of aldosterone synthase.	Potassium	0-9	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	207-227
15134802-5	2004	Such a mechanism would explain several inconsistencies in the literature, including the anomalous distribution of steroidogenic enzymes in the glomerulosa, the stimulation of CYP11B1 products by aldosterone secretagogues such as potassium ions or angiotensin II, the partial dependence of aldosterone secretion in vivo on an intact pituitary, the sensitivity of aldosterone secretion to tissue disruption in vitro, and the "late pathway" regulation of aldosterone synthesis.	Potassium	229-238	cytochrome P450, family 11, subfamily b, polypeptide 1	Rattus norvegicus	175-182
14592811-8	2004	In cells stably transfected with the Kir6.2 subunit of the of KATP channel, inhibition of glycolysis activated potassium current and NKCC activity.	Potassium	111-120	potassium inwardly-rectifying channel, subfamily J, member 11	Rattus norvegicus	37-43
15017529-9	2004	Thus, withdrawal of an ACE inhibitor in such patients should occur only when the rise in creatinine exceeds this threshold over a shorter period of time or hyperkalemia develops, ie, serum potassium level of 5.6 mmol/L or greater.	Potassium	189-198	angiotensin I converting enzyme	Homo sapiens	23-26
15259279-6	2004	RESULTS: Treatment with MPA caused a significant increase in vasoconstriction, expressed as E(max) (mN/mm, mean +/- SEM; p &lt; 0.05), in response to potassium (3.18 +/- 0.19 vs. 2.47 +/- 0.19) and calcium (4.00 +/- 0.22 vs. 3.34 +/- 0.14) in the posterior cerebral artery, and to endothelin-1 (6.88 +/- 0.69 vs. 5.22 +/- 0.30) in the basilar artery, when compared with NETA.	Potassium	150-159	endothelin-1	Oryctolagus cuniculus	281-293
15086776-4	2004	Vasoconstriction induced by endothelin-1 (ET-1), which is mainly an endothelin type A receptor agonist (Emax = 181 +/- 2% of potassium), and the endothelin type B receptor agonist, sarafotoxin 6c (Emax = 30 +/- 1%), were significantly increased after VAC therapy (ET-1; 325 +/- 3% and sarafotoxin 6c; 69 +/- 1%).	Potassium	125-134	endothelin-1	Sus scrofa	28-40
14679187-1	2004	High frequency firing in mammalian neurons requires ultra-rapid delayed rectifier potassium currents generated by homomeric or heteromeric assemblies of Kv3.1 and Kv3.2 potassium channel alpha subunits.	Potassium	82-91	potassium voltage-gated channel subfamily C member 1	Homo sapiens	153-158
14679187-1	2004	High frequency firing in mammalian neurons requires ultra-rapid delayed rectifier potassium currents generated by homomeric or heteromeric assemblies of Kv3.1 and Kv3.2 potassium channel alpha subunits.	Potassium	82-91	potassium voltage-gated channel subfamily C member 2	Homo sapiens	163-168
14679187-6	2004	The findings illustrate a mechanism for dynamic expansion of the functional repertoire of Kv3.1 and Kv3.2 potassium currents and suggest roles for these alpha subunits outside the scope of sustained rapid neuronal firing.	Potassium	106-115	potassium voltage-gated channel subfamily C member 2	Homo sapiens	100-105
14604981-1	2004	The ROMK subtypes of inward rectifier K+ channels (Kir 1.1, KCNJ1) mediate potassium secretion and regulate NaCl reabsorption in the kidney.	Potassium	75-84	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	4-8
14604981-1	2004	The ROMK subtypes of inward rectifier K+ channels (Kir 1.1, KCNJ1) mediate potassium secretion and regulate NaCl reabsorption in the kidney.	Potassium	75-84	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	51-58
14604981-1	2004	The ROMK subtypes of inward rectifier K+ channels (Kir 1.1, KCNJ1) mediate potassium secretion and regulate NaCl reabsorption in the kidney.	Potassium	75-84	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	60-65
14766178-2	2004	Potassium currents in olfactory bulb mitral cells from Kv1.3 null mice have slow inactivation kinetics, a modified voltage dependence, and a dampened C-type inactivation and fail to be modulated by activators of receptor tyrosine signaling cascades.	Potassium	0-9	potassium voltage-gated channel, shaker-related subfamily, member 3	Mus musculus	55-60
14746925-0	2004	Effects of berberine on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus.	Potassium	24-33	carbonic anhydrase 1	Rattus norvegicus	63-66
14742502-3	2004	Here we report that one of the isolated serum-susceptible mutants had a mutation in an open reading frame identified as trkA, a gene encoding an amino acid sequence showing high identity to that of TrkA of Vibrio alginolyticus, a protein required for the uptake of potassium.	Potassium	265-274	neurotrophic tyrosine kinase, receptor, type 1	Mus musculus	120-124
17021526-0	2004	New perspectives for an old cure: a glucose-insulin-potassium revival in cardiac surgery?	Potassium	52-61	insulin	Homo sapiens	44-51
14742502-3	2004	Here we report that one of the isolated serum-susceptible mutants had a mutation in an open reading frame identified as trkA, a gene encoding an amino acid sequence showing high identity to that of TrkA of Vibrio alginolyticus, a protein required for the uptake of potassium.	Potassium	265-274	neurotrophic tyrosine kinase, receptor, type 1	Mus musculus	198-202
14742502-6	2004	In addition, infection experiments demonstrated virulence attenuation when this mutant was administered intraperitoneally or subcutaneously to both normal and iron-treated mice, indicating that TrkA may modulate the transport of potassium and resistance to host innate defenses and that it is important for virulence in mice.	Potassium	229-238	neurotrophic tyrosine kinase, receptor, type 1	Mus musculus	194-198
14678080-0	2004	Effect of urinary trypsin inhibitor on potassium currents: fetus modulates membrane excitability by production of UTI.	Potassium	39-48	alpha-1-microglobulin/bikunin precursor	Homo sapiens	10-35
14678080-0	2004	Effect of urinary trypsin inhibitor on potassium currents: fetus modulates membrane excitability by production of UTI.	Potassium	39-48	alpha-1-microglobulin/bikunin precursor	Homo sapiens	114-117
14678080-7	2004	Administration of 1 micro M UTI significantly increased these potassium currents by 16.9%.	Potassium	62-71	alpha-1-microglobulin/bikunin precursor	Homo sapiens	28-31
14678080-8	2004	When calcium channels were blocked by the administration of cadmium, UTI increased the rest of the potassium currents by 4.8%.	Potassium	99-108	alpha-1-microglobulin/bikunin precursor	Homo sapiens	69-72
14678080-9	2004	This indicates that UTI increased calcium-dependent potassium currents by 94.8% but only increased voltage-dependent potassium currents by 4.8%.	Potassium	52-61	alpha-1-microglobulin/bikunin precursor	Homo sapiens	20-23
14678080-9	2004	This indicates that UTI increased calcium-dependent potassium currents by 94.8% but only increased voltage-dependent potassium currents by 4.8%.	Potassium	117-126	alpha-1-microglobulin/bikunin precursor	Homo sapiens	20-23
15176423-2	2004	Inhibition of HERG potassium currents by class III antiarrhythmic drugs causes lengthening of the cardiac action potential, which produces a beneficial antiarrhythmic effect.	Potassium	19-28	potassium voltage-gated channel subfamily H member 2	Homo sapiens	14-18
14684409-2	2004	Estimation of the net rate of endogenous non-carbonic acid production (NEAP) from dietary protein and potassium content enables exploration of the effects of dietary acidity or alkalinity on bone.	Potassium	102-111	dual specificity phosphatase 26	Homo sapiens	71-75
15350154-16	2004	The long-acting beta2-agonists cause predictable adverse effects including headache, tremor, palpitations, muscle cramps and a fall in serum potassium concentration.	Potassium	141-150	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	16-21
15581058-3	2004	The pathogenesis of AIDS-related KS is related to a system of cytokines (e.g., interleukin-6) driven by autocrine and paracrine loops.	Potassium	33-35	interleukin 6	Homo sapiens	79-92
15084142-6	2004	Single doses of beta(2)-adrenoceptor agonists significantly increase heart rate and decrease potassium concentrations compared with placebo.	Potassium	93-102	adrenoceptor beta 2	Homo sapiens	16-36
15084142-7	2004	CONCLUSIONS: Initiation of beta(2)-adrenoceptor agonist treatment increases heart rate and decreases potassium concentrations, while continued use may increase the risk of adverse cardiovascular events.	Potassium	101-110	adrenoceptor beta 2	Homo sapiens	27-47
15198370-1	2004	Na+,K(+)-ATPase is an ubiquitous membrane enzyme that allows the extrusion of three sodium ions from the cell and two potassium ions from the extracellular fluid.	Potassium	118-127	dynein axonemal heavy chain 8	Homo sapiens	9-15
15783125-5	2004	Although renal and intestinal adaptation are important in maintaining overall potassium balance during CKD, movement of potassium into the cells is extremely important in the body"s acute defense against hyperkalemia, and occurs daily during postprandial potassium overload, through shift of this cation into hepatic cells mediated by insulin and thus avoiding post-prandial hyperkalemia.	Potassium	120-129	insulin	Homo sapiens	335-342
15783125-5	2004	Although renal and intestinal adaptation are important in maintaining overall potassium balance during CKD, movement of potassium into the cells is extremely important in the body"s acute defense against hyperkalemia, and occurs daily during postprandial potassium overload, through shift of this cation into hepatic cells mediated by insulin and thus avoiding post-prandial hyperkalemia.	Potassium	120-129	insulin	Homo sapiens	335-342
15783126-6	2004	In peritoneal dialysis patients, despite lower potassium removal (about 30-40 mmol/day), hypokalemia is the most frequent electrolyte alteration, probably due to movement of potassium into the cells mediated by insulin, secondary to glucose absorption from the dialysis solution.	Potassium	174-183	insulin	Homo sapiens	211-218
15545011-4	2004	Incubation with a pan-PKC inhibitor, Ro-31-8220 (2 microm), or a specific PKCAlpha inhibitor, Go6976, protected cerebellar granule cell neurons from low potassium-mediated cell death.	Potassium	153-162	protein kinase C alpha	Homo sapiens	74-82
14689445-11	2004	Nevertheless, expression of Twik-2 within the stria vascularis suggests a potential role for this protein as one of the terminal components of the potassium ion-recycling pathway that contributes toward its reabsorption into the endolymph.	Potassium	147-156	potassium two pore domain channel subfamily K member 6	Homo sapiens	28-34
15120846-10	2004	Current-voltage relationship revealed that both the suppression of a potassium conductance and the activation of a cationic conductance are involved in the neurotensin-induced depolarization.	Potassium	69-78	neurotensin	Rattus norvegicus	156-167
15545011-0	2004	Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway.	Potassium	65-74	proline rich transmembrane protein 2	Homo sapiens	14-30
15545011-0	2004	Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway.	Potassium	65-74	AKT serine/threonine kinase 1	Homo sapiens	86-89
15545011-2	2004	Protein kinase C (PKC) is known to play a role in preventing neuronal apoptosis under trophic factor deprivation, but its role in protecting cerebellar neurons from cell death under conditions of low potassium is unknown.	Potassium	200-209	proline rich transmembrane protein 2	Homo sapiens	0-16
15545011-7	2004	Western blot analysis showed that serum-free, low potassium conditions decreased Akt phosphorylation, which was exacerbated by treatment with LY294002.	Potassium	50-59	AKT serine/threonine kinase 1	Homo sapiens	81-84
15545011-8	2004	In contrast, PKC inhibitors, Go6976 or Ro-31-8220, increased Akt phosphorylation approximately two and four-fold, respectively in low potassium conditions.	Potassium	134-143	proline rich transmembrane protein 2	Homo sapiens	13-16
15545011-8	2004	In contrast, PKC inhibitors, Go6976 or Ro-31-8220, increased Akt phosphorylation approximately two and four-fold, respectively in low potassium conditions.	Potassium	134-143	AKT serine/threonine kinase 1	Homo sapiens	61-64
15545011-3	2004	This study sought to determine the involvement of PKC in neuronal survival and to determine if PKC regulated the phosphatidylinositol 3-kinase (PI 3-K)/Akt pathway in low physiologic concentrations of potassium.	Potassium	201-210	proline rich transmembrane protein 2	Homo sapiens	95-98
15138361-6	2004	Finally, the paclitaxel sensitivity of the CD40-negative cell line KS was compared to that of its CD40-positive transfectant KS-CD40.	Potassium	67-69	CD40 molecule	Homo sapiens	43-47
15545011-3	2004	This study sought to determine the involvement of PKC in neuronal survival and to determine if PKC regulated the phosphatidylinositol 3-kinase (PI 3-K)/Akt pathway in low physiologic concentrations of potassium.	Potassium	201-210	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Homo sapiens	113-142
15138361-6	2004	Finally, the paclitaxel sensitivity of the CD40-negative cell line KS was compared to that of its CD40-positive transfectant KS-CD40.	Potassium	125-127	CD40 molecule	Homo sapiens	98-102
15138361-6	2004	Finally, the paclitaxel sensitivity of the CD40-negative cell line KS was compared to that of its CD40-positive transfectant KS-CD40.	Potassium	125-127	CD40 molecule	Homo sapiens	98-102
14684859-8	2003	Low-threshold potassium currents (IKL) predominate in males.	Potassium	14-23	IK cytokine L homeolog	Xenopus laevis	34-37
12952854-8	2003	The intensity of UT-A1 and UT-A3 immunoreactivity in the IMCD was markedly reduced in potassium-depleted mice.	Potassium	86-95	solute carrier family 14 (urea transporter), member 2	Mus musculus	17-22
15292245-8	2004	We found that, in cultured granule neurons in which apoptosis was induced by serum deprivation and low potassium concentration, a C5aR agonist promoted cell survival and inhibited caspase-3 activation and DNA fragmentation.	Potassium	103-112	complement C5a receptor 1	Rattus norvegicus	130-134
12952854-8	2003	The intensity of UT-A1 and UT-A3 immunoreactivity in the IMCD was markedly reduced in potassium-depleted mice.	Potassium	86-95	solute carrier family 14 (urea transporter), member 2	Mus musculus	27-32
12952854-10	2003	The intensity of UT-B immunoreactivity in the descending vasa recta (DVR) was reduced in potassium-depleted animals compared with controls.	Potassium	89-98	solute carrier family 14 (urea transporter), member 1	Mus musculus	17-21
12952854-12	2003	In summary, potassium depletion is associated with reduced expression of UT-A1, UT-A3, and UT-B but increased expression of UT-A2.	Potassium	12-21	solute carrier family 14 (urea transporter), member 2	Mus musculus	73-78
12952854-12	2003	In summary, potassium depletion is associated with reduced expression of UT-A1, UT-A3, and UT-B but increased expression of UT-A2.	Potassium	12-21	solute carrier family 14 (urea transporter), member 2	Mus musculus	80-85
12952854-12	2003	In summary, potassium depletion is associated with reduced expression of UT-A1, UT-A3, and UT-B but increased expression of UT-A2.	Potassium	12-21	solute carrier family 14 (urea transporter), member 1	Mus musculus	91-95
12952855-0	2003	Dietary potassium restriction stimulates endocytosis of ROMK channel in rat cortical collecting duct.	Potassium	8-17	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	56-60
14646167-4	2003	In conclusion, these evaluation methods demonstrated that ER-118585 could prolong the QT interval via APD prolongation, attributable to the inhibition of the HERG potassium current.	Potassium	163-172	potassium voltage-gated channel subfamily H member 2	Homo sapiens	158-162
14634689-5	2003	Furthermore, the mean serum potassium values of obese individuals were significantly higher in the CHE2 C5+ than in the CHE2 C5- phenotype.	Potassium	28-37	butyrylcholinesterase	Homo sapiens	99-103
14645681-7	2003	An oligonucleotide containing the PEnk cAMP response element-2 was gel-shifted by both unstimulated and potassium-stimulated chromaffin cell nuclear extracts into a prominent complex supershifted by CREB antibodies.	Potassium	104-113	proenkephalin	Homo sapiens	34-38
14645681-7	2003	An oligonucleotide containing the PEnk cAMP response element-2 was gel-shifted by both unstimulated and potassium-stimulated chromaffin cell nuclear extracts into a prominent complex supershifted by CREB antibodies.	Potassium	104-113	cAMP responsive element binding protein 1	Homo sapiens	199-203
14625085-0	2003	Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons.	Potassium	108-117	brain-derived neurotrophic factor	Rattus norvegicus	36-69
14625085-6	2003	BDNF and IGF-1 suppressed the activation of p38 and c-Jun, but not of c-Jun N-terminal kinase (JNK), caused by lowering the potassium concentration.	Potassium	124-133	brain-derived neurotrophic factor	Rattus norvegicus	0-4
14625085-6	2003	BDNF and IGF-1 suppressed the activation of p38 and c-Jun, but not of c-Jun N-terminal kinase (JNK), caused by lowering the potassium concentration.	Potassium	124-133	insulin-like growth factor 1	Rattus norvegicus	9-14
14625085-6	2003	BDNF and IGF-1 suppressed the activation of p38 and c-Jun, but not of c-Jun N-terminal kinase (JNK), caused by lowering the potassium concentration.	Potassium	124-133	mitogen activated protein kinase 14	Rattus norvegicus	44-47
14623130-1	2003	The recent discovery that subsets of rat taste receptor cells (TRCs) express the peptide cholecystokinin (CCK) and that subsets of TRCs respond to CCK with altered potassium currents or elevated intracellular calcium via CCK-A receptor has lead to the hypothesis that CCK may play a novel signaling role within the taste bud, perhaps modifying tastant responses by co-transmission with a classic transmitter.	Potassium	164-173	cholecystokinin	Rattus norvegicus	147-150
14623130-1	2003	The recent discovery that subsets of rat taste receptor cells (TRCs) express the peptide cholecystokinin (CCK) and that subsets of TRCs respond to CCK with altered potassium currents or elevated intracellular calcium via CCK-A receptor has lead to the hypothesis that CCK may play a novel signaling role within the taste bud, perhaps modifying tastant responses by co-transmission with a classic transmitter.	Potassium	164-173	cholecystokinin	Rattus norvegicus	147-150
14612589-4	2003	In particular, channels expressing the beta3b-V4 variant displayed a right shift in the potassium current voltage-dependence of activation and inactivated to about 30% of the maximum conductance, compared with wild-type beta3b channels that showed no inactivation.	Potassium	88-97	apolipoprotein B mRNA editing enzyme catalytic subunit 3B	Homo sapiens	39-45
12869368-9	2003	ANG II decreased sodium excretion by 70%, potassium excretion by 50%, and urine flow by 80%, whereas urine osmolality increased.	Potassium	42-51	angiogenin	Homo sapiens	0-3
14636320-9	2003	When extracellular potassium was elevated and excitatory synaptic transmission was blocked, antidromic activation or short pulses of intracellular depolarizing current evoked voltage-dependent bursts of action potentials in the majority of cells recorded in Kcna1 null slices, but only single spikes in control slices.	Potassium	19-28	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	258-263
14636320-12	2003	This property of CA3 neurons, seen particularly when tissue conditions become abnormal (e.g., elevated extracellular potassium), helps to explain the high seizure susceptibility of Kcna1-null mice.	Potassium	117-126	carbonic anhydrase 3	Mus musculus	17-20
14636320-12	2003	This property of CA3 neurons, seen particularly when tissue conditions become abnormal (e.g., elevated extracellular potassium), helps to explain the high seizure susceptibility of Kcna1-null mice.	Potassium	117-126	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	181-186
14674677-3	2003	Potassium currents in HEK 293 cells stably transfected with HERG were recorded using a whole cell voltage clamp method.	Potassium	0-9	potassium voltage-gated channel subfamily H member 2	Homo sapiens	60-64
14674677-4	2003	Exposure of cells to erythromycin reduced the HERG encoded potassium current in a concentration dependent manner with an IC50 of 38.9 +/- 1.2 microM and Hill Slope factor of 0.4 +/- 0.1.	Potassium	59-68	potassium voltage-gated channel subfamily H member 2	Homo sapiens	46-50
14674677-7	2003	The results of this study document that both erythromycin and clarithromycin significantly inhibit the HERG potassium current at clinically relevant concentrations.	Potassium	108-117	potassium voltage-gated channel subfamily H member 2	Homo sapiens	103-107
14972007-11	2003	There was a non-significant trend to decreased serum potassium levels 1 hour after colonoscopy in patients prepared with NaP (63.6 vs 36.4%).	Potassium	53-62	catenin beta like 1	Homo sapiens	121-124
14972007-12	2003	The multivariate analysis showed that low potassium levels were independently associated with age and NaP preparation.	Potassium	42-51	catenin beta like 1	Homo sapiens	102-105
14642687-0	2003	A new oral therapy for long QT syndrome: long-term oral potassium improves repolarization in patients with HERG mutations.	Potassium	56-65	potassium voltage-gated channel subfamily H member 2	Homo sapiens	107-111
14642687-1	2003	OBJECTIVES: We sought to determine whether oral potassium supplementation safely increases serum K(+) and results in sustained improvement of repolarization parameters in long QT syndrome type 2 (LQT2) subjects.	Potassium	48-57	potassium voltage-gated channel subfamily H member 2	Homo sapiens	196-200
14642687-4	2003	We tested the hypothesis that long-term oral potassium supplementation results in a mild, sustainable increase in serum K(+) that improves repolarization abnormalities in subjects with LQT2.	Potassium	45-54	potassium voltage-gated channel subfamily H member 2	Homo sapiens	185-189
14642687-13	2003	CONCLUSIONS: Long-term oral potassium administration increases serum K(+) in patients with LQT2.	Potassium	28-37	potassium voltage-gated channel subfamily H member 2	Homo sapiens	91-95
14613852-2	2003	Mutations in the human-ether-a-go-go-related gene (hERG), encoding the protein underlying the repolarizing cardiac I(Kr) potassium current, cause chromosome 7-linked long QT syndrome 2.	Potassium	121-130	ETS transcription factor ERG	Homo sapiens	51-55
14634689-5	2003	Furthermore, the mean serum potassium values of obese individuals were significantly higher in the CHE2 C5+ than in the CHE2 C5- phenotype.	Potassium	28-37	butyrylcholinesterase	Homo sapiens	120-124
14638708-10	2003	As expected, expression of K3 was negative in the basal layer of L/Ls, but positive in that of K/Ks.	Potassium	97-99	keratin, type II cytoskeletal 3	Oryctolagus cuniculus	27-29
14710356-3	2003	MEF2D is hyperphosphorylated and degraded in CGNs undergoing apoptosis induced by lowering the extracellular potassium concentration from 25 mM to 5 mM.	Potassium	109-118	myocyte enhancer factor 2D	Rattus norvegicus	0-5
14638708-11	2003	Expression of K3 was sporadically positive in the basal layer of L/Ks but largely negative in that of K/Ls.	Potassium	67-69	keratin, type II cytoskeletal 3	Oryctolagus cuniculus	14-16
14638708-12	2003	Expression of Cx43 was uniformly expressed in the basal layer of the K/Ks, but weak in that of L/Ls, K/Ls, and L/Ks.	Potassium	71-73	gap junction alpha-1 protein	Oryctolagus cuniculus	14-18
14638708-12	2003	Expression of Cx43 was uniformly expressed in the basal layer of the K/Ks, but weak in that of L/Ls, K/Ls, and L/Ks.	Potassium	113-115	gap junction alpha-1 protein	Oryctolagus cuniculus	14-18
14618071-0	2003	AHP"s, HAP"s and DAP"s: how potassium currents regulate the excitability of rat supraoptic neurones.	Potassium	28-37	death-associated protein	Rattus norvegicus	17-20
12949139-4	2003	The Ka/Ks ratios are generally greater than 3 for GPA, GPB, and GPE in human, chimpanzee, and gorilla, indicating positive selection.	Potassium	7-9	glycophorin B (MNS blood group)	Homo sapiens	55-58
14563363-4	2003	Functional expression of recombinant AMIH in HEK293 cells gave unitary currents that were preferentially selective for potassium over sodium ions and were activated by hyperpolarizing voltage steps.	Potassium	119-128	hyperpolarization-activated ion channel	Apis mellifera	37-41
12949139-4	2003	The Ka/Ks ratios are generally greater than 3 for GPA, GPB, and GPE in human, chimpanzee, and gorilla, indicating positive selection.	Potassium	7-9	glycophorin E (MNS blood group)	Homo sapiens	64-67
14620033-2	2003	We investigated age-dependent alterations of inwardly rectifying potassium (Kir) currents in Muller glial cells of the human retina.	Potassium	65-74	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	76-79
14529724-3	2003	Phosphorylation of ERK1/2 induced by TPA and co-application of high potassium and glutamate was greatly attenuated by preincubating Purkinje cells with the MEK1/2 (MAPK ERK kinase 1/2) inhibitor PD98059.	Potassium	68-77	mitogen-activated protein kinase 3	Homo sapiens	19-25
14529724-3	2003	Phosphorylation of ERK1/2 induced by TPA and co-application of high potassium and glutamate was greatly attenuated by preincubating Purkinje cells with the MEK1/2 (MAPK ERK kinase 1/2) inhibitor PD98059.	Potassium	68-77	mitogen-activated protein kinase kinase 1	Homo sapiens	156-162
14529724-3	2003	Phosphorylation of ERK1/2 induced by TPA and co-application of high potassium and glutamate was greatly attenuated by preincubating Purkinje cells with the MEK1/2 (MAPK ERK kinase 1/2) inhibitor PD98059.	Potassium	68-77	mitogen-activated protein kinase kinase 1	Homo sapiens	164-183
14529724-5	2003	The MEK1/2 inhibitor also suppressed declustering of the ionotropic glutamate receptor subunit 2/3 (GluR2/3) induced by TPA and co-application of high potassium and glutamate, even though phosphorylation of Ser880 of GluR2/3 was not inhibited significantly in the presence of PD98059.	Potassium	151-160	mitogen-activated protein kinase kinase 1	Homo sapiens	4-10
14529724-5	2003	The MEK1/2 inhibitor also suppressed declustering of the ionotropic glutamate receptor subunit 2/3 (GluR2/3) induced by TPA and co-application of high potassium and glutamate, even though phosphorylation of Ser880 of GluR2/3 was not inhibited significantly in the presence of PD98059.	Potassium	151-160	glutamate ionotropic receptor AMPA type subunit 3	Homo sapiens	68-98
14529724-5	2003	The MEK1/2 inhibitor also suppressed declustering of the ionotropic glutamate receptor subunit 2/3 (GluR2/3) induced by TPA and co-application of high potassium and glutamate, even though phosphorylation of Ser880 of GluR2/3 was not inhibited significantly in the presence of PD98059.	Potassium	151-160	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	100-107
12881519-9	2003	Furthermore, potassium permanganate probing shows that the conformation of the open complex in the presence of CRP appears qualitatively and quantitatively different from that in the absence of CRP, suggesting that contact with RNA polymerase is maintained throughout the transcription initiation.	Potassium	13-22	catabolite gene activator protein	Escherichia coli	111-114
14575452-7	2003	Theoretical calculations for 1(2T) and 1(3T) at the B3LYP/6-31G(d) level indicated that the annelation with BCO units either at the 2,3- or 3,4-positions of thiophene rings raises both the KS HOMO and LUMO levels.	Potassium	189-191	beta-carotene oxygenase 1	Homo sapiens	108-111
14555474-3	2003	By using a novel genetic screen in which potassium uptake was made dependent on amino acid signaling, we obtained gain-of-function mutations in SSY1.	Potassium	41-50	Ssy1p	Saccharomyces cerevisiae S288C	144-148
14516451-10	2003	However, when magnesium and potassium were added to PAS-III, the concentrations of platelet-derived cytokines obtained during storage were about the same as those produced by platelets stored in plasma.	Potassium	28-37	mucin 15, cell surface associated	Homo sapiens	52-59
14499621-9	2003	Cytochrome c-linked caspase activation also led to potassium efflux out of the cell.	Potassium	51-60	cytochrome c, somatic	Homo sapiens	0-12
14636008-6	2003	CONCLUSION: MARS exchanges potassium, chloride, calcium, and magnesium by ultrafiltration; sodium by the albumin dialysis.	Potassium	27-36	methionyl-tRNA synthetase 1	Homo sapiens	12-16
14622172-0	2003	Contribution of Kir3.1, Kir3.2A and Kir3.2C subunits to native G protein-gated inwardly rectifying potassium currents in cultured hippocampal neurons.	Potassium	99-108	potassium inwardly rectifying channel subfamily J member 3	Homo sapiens	16-22
14622174-2	2003	The mGluR1-induced conductance reversed polarity close to 0 mV and at more positive potentials when extracellular potassium concentrations were increased, indicating the involvement of a cationic channel.	Potassium	114-123	glutamate metabotropic receptor 1	Rattus norvegicus	4-10
14527710-6	2003	methadone causes QTc prolongation in humans; (2) whether methadone and/or chlorobutanol block cardiac HERG potassium currents (IHERG) in vitro.	Potassium	107-116	potassium voltage-gated channel subfamily H member 2	Homo sapiens	102-106
14516451-0	2003	Storage of platelets in additive solutions: the effects of magnesium and potassium on the release of RANTES, beta-thromboglobulin, platelet factor 4 and interleukin-7, during storage.	Potassium	73-82	C-C motif chemokine ligand 5	Homo sapiens	101-107
12934070-1	2003	The potassium ionophore nigericin induces cell death and promotes the maturation and release of IL-1beta in lipopolysaccharide (LPS)-primed monocytes and macrophages, the latter depending on caspase-1 activation by an unknown mechanism.	Potassium	4-13	interleukin 1 beta	Homo sapiens	96-104
12954870-7	2003	Thus, MiRP2, unlike other known neuronal beta subunits, provides a mechanism for influence over multiple delayed rectifier potassium currents in mammalian CNS via modulation of alpha subunits from structurally and kinetically distinct subfamilies.	Potassium	123-132	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	6-11
12680712-1	2003	Previously, we reported that the ATPase activity of GroEL that requires potassium and magnesium was highly temperature dependent in the 25-60 degrees C range.	Potassium	72-81	dynein axonemal heavy chain 8	Homo sapiens	33-39
12680712-1	2003	Previously, we reported that the ATPase activity of GroEL that requires potassium and magnesium was highly temperature dependent in the 25-60 degrees C range.	Potassium	72-81	heat shock protein family D (Hsp60) member 1	Homo sapiens	52-57
12680712-2	2003	Here, we report that the monovalent cations, rubidium and ammonium were able to fully substitute for potassium; while the divalent cations manganese, cobalt, and nickel supported the ATPase activity of GroEL albeit to a lesser degree than magnesium.	Potassium	101-110	heat shock protein family D (Hsp60) member 1	Homo sapiens	202-207
12934070-1	2003	The potassium ionophore nigericin induces cell death and promotes the maturation and release of IL-1beta in lipopolysaccharide (LPS)-primed monocytes and macrophages, the latter depending on caspase-1 activation by an unknown mechanism.	Potassium	4-13	caspase 1	Homo sapiens	191-200
14499862-7	2003	Coexpression of KCNQ1 together with wild type KCNE1 and G52R-KCNE1 reduced the wild-type I(ks) current amplitude by 50%, whereas other biophysical properties of the I(ks) were not altered.	Potassium	91-93	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	16-21
14499862-7	2003	Coexpression of KCNQ1 together with wild type KCNE1 and G52R-KCNE1 reduced the wild-type I(ks) current amplitude by 50%, whereas other biophysical properties of the I(ks) were not altered.	Potassium	91-93	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	46-51
12750418-4	2003	PKA, PKC, and ERK exert inhibitory effects on transient potassium currents (A-type currents or IA) in mouse superficial dorsal horn neurons (Hu et al.	Potassium	56-65	mitogen-activated protein kinase 1	Mus musculus	14-17
14499862-7	2003	Coexpression of KCNQ1 together with wild type KCNE1 and G52R-KCNE1 reduced the wild-type I(ks) current amplitude by 50%, whereas other biophysical properties of the I(ks) were not altered.	Potassium	91-93	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	61-66
14499862-7	2003	Coexpression of KCNQ1 together with wild type KCNE1 and G52R-KCNE1 reduced the wild-type I(ks) current amplitude by 50%, whereas other biophysical properties of the I(ks) were not altered.	Potassium	167-169	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	16-21
14499862-7	2003	Coexpression of KCNQ1 together with wild type KCNE1 and G52R-KCNE1 reduced the wild-type I(ks) current amplitude by 50%, whereas other biophysical properties of the I(ks) were not altered.	Potassium	167-169	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	61-66
14499862-9	2003	The mutant G52R-KCNE1 has a dominant negative effect on I(ks) current, which reduces the I(ks) current amplitude and leads to a prolongation of the cardiac action potential.	Potassium	58-60	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	16-21
14499862-9	2003	The mutant G52R-KCNE1 has a dominant negative effect on I(ks) current, which reduces the I(ks) current amplitude and leads to a prolongation of the cardiac action potential.	Potassium	91-93	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	16-21
12920401-5	2003	Barttin is a beta-subunit that is required for the trafficking of CLC-K (both ClC-Ka and ClC-Kb) channels to the plasma membrane in both the thick ascending limb and the marginal cells in the scala media of the inner ear that secrete potassium ion-rich endolymph.	Potassium	234-243	barttin CLCNK type accessory subunit beta	Homo sapiens	0-7
12920401-5	2003	Barttin is a beta-subunit that is required for the trafficking of CLC-K (both ClC-Ka and ClC-Kb) channels to the plasma membrane in both the thick ascending limb and the marginal cells in the scala media of the inner ear that secrete potassium ion-rich endolymph.	Potassium	234-243	chloride voltage-gated channel Kb	Homo sapiens	66-71
12807917-8	2003	Thus, Fas ligand increases Kv1.3 channel activity through the same canonical apoptotic signaling cascade that is required for potassium efflux, cell shrinkage, and apoptosis.	Potassium	126-135	Fas ligand	Homo sapiens	6-16
12970879-3	2003	Its products were separately cloned into the Sma I site of pBluescript KS(+) to generate both plasmids pBS/SS and pBS/LS.	Potassium	71-73	survival of motor neuron 1, telomeric	Homo sapiens	45-48
12970879-3	2003	Its products were separately cloned into the Sma I site of pBluescript KS(+) to generate both plasmids pBS/SS and pBS/LS.	Potassium	71-73	cholinergic receptor muscarinic 3	Homo sapiens	103-106
15169664-2	2003	METHODS: The genes encoding K chain and Fd against gamma-seminoprotein were acquired from pUC19-K and pBluescript KS( M13-)-Fd by restrictive enzyme digestion and then cloned into the expression vector pComb3 to construct recombinant expression vector pComb3-Fab.	Potassium	114-116	kallikrein related peptidase 3	Homo sapiens	51-70
12807917-8	2003	Thus, Fas ligand increases Kv1.3 channel activity through the same canonical apoptotic signaling cascade that is required for potassium efflux, cell shrinkage, and apoptosis.	Potassium	126-135	potassium voltage-gated channel subfamily A member 3	Homo sapiens	27-32
12937818-1	2003	The effects of aluminum chloride (AlCl3) on the transient outward potassium and delayed rectifier K(+) current in hippocampal CA1 neurons of rats were studied by the whole-cell patch clamp technique.	Potassium	66-75	carbonic anhydrase 1	Rattus norvegicus	126-129
12871719-5	2003	Treating cells with elevated extracellular potassium caused membrane depolarization and stimulation of rubidium efflux through KCNQ2.	Potassium	43-52	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	127-132
12953161-6	2003	Ghrelin output was detected in the incubation fluid of rat hypothalamic explants and could be stimulated with high potassium concentrations.	Potassium	115-124	ghrelin and obestatin prepropeptide	Rattus norvegicus	0-7
12890474-5	2003	Activation of cholinergic receptors in cultured chick atrial myocytes by carbachol produced an outward potassium current (I(K(ACh))), which was attenuated by 24-48-h pre-treatment with neuregulin-1.	Potassium	103-112	neuregulin 1	Gallus gallus	185-197
12783865-8	2003	The pyrophosphatase activity was potassium-insensitive and inhibited by the pyrophosphate analogs, amynomethylenediphosphonate and imidodiphosphate, by dicyclohexylcarbodiimide, and by the thiol reagent N-ethylmaleimide.	Potassium	33-42	AWN88_RS23445	Agrobacterium tumefaciens	4-19
12796490-10	2003	In searching for a link between the P2X7 receptor and the activation of ICE, we found that enhancing potassium efflux from Schwann cells upregulated the production of IL-1beta, while strongly reducing potassium efflux led to opposite effects.	Potassium	101-110	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	36-49
12796490-10	2003	In searching for a link between the P2X7 receptor and the activation of ICE, we found that enhancing potassium efflux from Schwann cells upregulated the production of IL-1beta, while strongly reducing potassium efflux led to opposite effects.	Potassium	101-110	caspase 1	Mus musculus	72-75
12796490-10	2003	In searching for a link between the P2X7 receptor and the activation of ICE, we found that enhancing potassium efflux from Schwann cells upregulated the production of IL-1beta, while strongly reducing potassium efflux led to opposite effects.	Potassium	101-110	interleukin 1 beta	Mus musculus	167-175
12796490-10	2003	In searching for a link between the P2X7 receptor and the activation of ICE, we found that enhancing potassium efflux from Schwann cells upregulated the production of IL-1beta, while strongly reducing potassium efflux led to opposite effects.	Potassium	201-210	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	36-49
12796490-10	2003	In searching for a link between the P2X7 receptor and the activation of ICE, we found that enhancing potassium efflux from Schwann cells upregulated the production of IL-1beta, while strongly reducing potassium efflux led to opposite effects.	Potassium	201-210	caspase 1	Mus musculus	72-75
12875994-2	2003	Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP).	Potassium	27-29	endothelin 1	Homo sapiens	44-48
12875994-2	2003	Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP).	Potassium	27-29	matrix metallopeptidase 2	Homo sapiens	87-113
12875994-2	2003	Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP).	Potassium	27-29	matrix metallopeptidase 2	Homo sapiens	115-141
12875994-2	2003	Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP).	Potassium	27-29	matrix metallopeptidase 14	Homo sapiens	157-176
12875994-2	2003	Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP).	Potassium	27-29	matrix metallopeptidase 14	Homo sapiens	178-185
12875994-7	2003	ET-1 induced a dose-dependent enhancement in KS IMM cell migration and MMP-dependent invasiveness that were inhibited by ET-1 receptor antagonists.	Potassium	45-47	endothelin 1	Homo sapiens	0-4
12875994-7	2003	ET-1 induced a dose-dependent enhancement in KS IMM cell migration and MMP-dependent invasiveness that were inhibited by ET-1 receptor antagonists.	Potassium	45-47	endothelin 1	Homo sapiens	121-125
12875994-8	2003	The small molecule, A-182086, an orally bioavailable ET(A/B)R antagonist, completely inhibited cell proliferation and tumor growth in KS IMM xenografts.	Potassium	134-136	endothelin receptor type A	Homo sapiens	53-61
12875994-9	2003	These findings demonstrate that ET-1-driven autocrine loop is crucial for enhanced invasiveness of KS IMM cells and promote tumor growth in vivo.	Potassium	99-101	endothelin 1	Homo sapiens	32-36
12919898-3	2003	RESULTS: The single channel conductance of BKCa recorded was 221+/-6 pS and the reversal potential was -0.12 mV in the presence of high potassium in the bathing and pipette solutions.	Potassium	136-145	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	43-47
12919898-6	2003	CONCLUSION: BKCa in rat mesenteric arterial smooth muscle cells has the properties of large conductance, high potassium selectivity, steep voltage dependence and high calcium sensitivity.	Potassium	110-119	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	12-16
12925696-1	2003	Aldosterone controls the final sodium reabsorption and potassium secretion in the kidney by regulating the activity of the epithelial sodium channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN).	Potassium	55-64	sodium channel, nonvoltage-gated 1 alpha	Mus musculus	150-154
12860380-0	2003	Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin.	Potassium	45-54	potassium voltage-gated channel subfamily H member 2	Homo sapiens	40-44
14562960-11	2003	Elevated Ka/Ks ratios within the Pan-Homo clade suggest a history of positive selection at semenogelin I.	Potassium	12-14	semenogelin 1	Pan troglodytes	91-104
12709395-12	2003	We postulate that KCC4 mediates potassium and chloride exit from the cell and may play an important role in salt absorption by the distal convoluted tubule.	Potassium	32-41	solute carrier family 12 member 7	Oryctolagus cuniculus	18-22
12860415-3	2003	Deletion of the Kv1.5 N-terminus eliminated the SAP97-mediated increase in potassium currents whereas deletion of the channel"s C-terminal PDZ binding motif had no effect.	Potassium	75-84	potassium voltage-gated channel subfamily A member 5	Rattus norvegicus	16-21
12860415-3	2003	Deletion of the Kv1.5 N-terminus eliminated the SAP97-mediated increase in potassium currents whereas deletion of the channel"s C-terminal PDZ binding motif had no effect.	Potassium	75-84	discs large MAGUK scaffold protein 1	Rattus norvegicus	48-53
12821145-2	2003	I(Ks) is modulated by PKC but the identity of which PKC isozymes is involved in this modulation is not known.	Potassium	2-4	proline rich transmembrane protein 2	Homo sapiens	22-25
12821145-3	2003	To dissect the role of individual PKC isozymes in the regulation of I(Ks), human cardiac I(Ks) channel (minK+KvLQT1) was expressed in Xenopus oocytes.	Potassium	70-72	proline rich transmembrane protein 2	Homo sapiens	34-37
12821145-7	2003	Peptide specific inhibitors for beta(II)PKC, and a general PKC inhibitor, calphostin C antagonized PMA-induced activation of I(Ks).	Potassium	127-129	proline rich transmembrane protein 2	Homo sapiens	59-62
12810578-4	2003	Ucn III secretion from the cells was measured using a highly specific RIA, and we found that high potassium, forskolin, or high glucose can stimulate Ucn III secretion from these cells.	Potassium	98-107	urocortin 3	Mus musculus	0-7
12839862-0	2003	Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652.	Potassium	17-26	potassium voltage-gated channel subfamily H member 2	Homo sapiens	12-16
12682056-0	2003	Specific potassium binding stabilizes pI258 arsenate reductase from Staphylococcus aureus.	Potassium	9-18	Arsenate reductase	Staphylococcus aureus	44-62
12682056-4	2003	Potassium has the largest affinity with a Ka of 3.8 x 10(3) m(-1), and the effectiveness of stabilization of ArsC by monovalent cations follows the binding affinity order: K+ &gt; Rb+ &gt; Cs+ &gt; Na+ &gt; Li+.	Potassium	0-9	Arsenate reductase	Staphylococcus aureus	109-113
12810578-4	2003	Ucn III secretion from the cells was measured using a highly specific RIA, and we found that high potassium, forskolin, or high glucose can stimulate Ucn III secretion from these cells.	Potassium	98-107	urocortin 3	Mus musculus	150-157
12828861-4	2003	Because the electrophysiologic mechanism of action of Q9E-hMiRP1 (i.e., diminished potassium currents resulting in delayed myocardial repolarization) is comparable to that of class III antiarrhythmic agents, we examined Q9E-hMiRP1 as a candidate gene therapy construct for site-specific treatment of reentrant atrial cardiac arrhythmias.	Potassium	83-92	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	58-64
13677548-3	2003	The etiology is multifactorial, but a fairly good marker is dysfunction of the glycosaminoglycan/mucus/mucin layer of the bladder as detected by a potassium (KCl) sensitivity test.	Potassium	147-156	LOC100508689	Homo sapiens	103-108
12767334-4	2003	Carbonate was found to have the lowest dissociation constant for activation (K(a)=1.1 mM) and potassium was stabilizing ArsC (DeltaT(m)=+6.2 degrees C).	Potassium	94-103	Arsenate reductase	Staphylococcus aureus	120-124
12684516-1	2003	The Kir1.1 (ROMK) subtypes of inward rectifier K+ channels mediate potassium secretion and regulate sodium chloride reabsorption in the kidney.	Potassium	67-76	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	4-10
12684516-1	2003	The Kir1.1 (ROMK) subtypes of inward rectifier K+ channels mediate potassium secretion and regulate sodium chloride reabsorption in the kidney.	Potassium	67-76	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	12-16
12804783-3	2003	Here we show that a hybrid protein composed of the Sod2 antiporter fused to the carboxy-terminal half of Nha1 strongly increased sodium tolerance, but did not allow growth at high potassium nor did rescue growth of the sit4 hal3 conditional mutant strain.	Potassium	180-189	superoxide dismutase SOD2	Saccharomyces cerevisiae S288C	51-55
12828861-10	2003	Patchclamp studies demonstrated that cells transfected with Q9E-hMiRP1 plasmid DNA exhibited significantly reduced potassium currents but only with clarithromycin administration.	Potassium	115-124	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	64-70
12804783-3	2003	Here we show that a hybrid protein composed of the Sod2 antiporter fused to the carboxy-terminal half of Nha1 strongly increased sodium tolerance, but did not allow growth at high potassium nor did rescue growth of the sit4 hal3 conditional mutant strain.	Potassium	180-189	Nha1p	Saccharomyces cerevisiae S288C	105-109
12782329-2	2003	In addition to a magnesium ion, which is essential for catalysis, a potassium ion bound adjacent to the triphosphate moiety of ATP in a rat mitochondrial protein kinase, BCK (branched-chain alpha-ketoacid dehydrogenase kinase), has been shown to be indispensable for nucleotide binding and hydrolysis.	Potassium	68-77	creatine kinase B	Rattus norvegicus	170-173
12782329-2	2003	In addition to a magnesium ion, which is essential for catalysis, a potassium ion bound adjacent to the triphosphate moiety of ATP in a rat mitochondrial protein kinase, BCK (branched-chain alpha-ketoacid dehydrogenase kinase), has been shown to be indispensable for nucleotide binding and hydrolysis.	Potassium	68-77	creatine kinase B	Rattus norvegicus	175-225
12935817-10	2003	Results suggest the hypothesis that keratocan, or keratocan with minimally sulfated KS chains, may play a role in structuring ECM for early embryonic cell and neuronal migrations.	Potassium	84-86	keratocan	Gallus gallus	36-45
12719438-2	2003	This region contains the WNK4 gene that causes the mendelian disorder pseudohypoaldosteronism type II, characterized by high potassium levels and hypertension.	Potassium	125-134	WNK lysine deficient protein kinase 4	Homo sapiens	25-29
12962276-9	2003	In contrast, the null mutation of kcne1 completely impaired volume-sensitive chloride and potassium currents in PCT.	Potassium	90-99	potassium voltage-gated channel, Isk-related subfamily, member 1	Mus musculus	34-39
12962278-0	2003	Stimulation of Na,K-ATPase by low potassium is dependent on transferrin.	Potassium	34-43	inhibitor of carbonic anhydrase	Canis lupus familiaris	60-71
12611589-6	2003	A protein consisting of a subunit with molecular mass of 90 kDa was shown to bind to KS type GST 3-3 but not to NC type.	Potassium	85-87	glutathione S-transferase mu 1	Rattus norvegicus	93-100
12611589-10	2003	These findings suggest that HSP90 interacts with KS type GST 3-3 and thereby protects it from inactivation due to CCl(4).	Potassium	49-51	heat shock protein 90 alpha family class A member 1	Rattus norvegicus	28-33
12611589-10	2003	These findings suggest that HSP90 interacts with KS type GST 3-3 and thereby protects it from inactivation due to CCl(4).	Potassium	49-51	glutathione S-transferase mu 1	Rattus norvegicus	57-64
12761106-1	2003	Salivary histatin 5 (Hst 5), a potent toxin for the human fungal pathogen Candida albicans, induces noncytolytic efflux of cellular ATP, potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin"s fungicidal activity.	Potassium	137-146	histatin 3	Homo sapiens	9-19
12761106-1	2003	Salivary histatin 5 (Hst 5), a potent toxin for the human fungal pathogen Candida albicans, induces noncytolytic efflux of cellular ATP, potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin"s fungicidal activity.	Potassium	137-146	histatin 3	Homo sapiens	21-26
12869527-0	2003	Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.	Potassium	60-69	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	0-36
12869527-0	2003	Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.	Potassium	60-69	mitogen-activated protein kinase 14	Homo sapiens	92-128
12869527-0	2003	Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.	Potassium	60-69	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	133-138
12869530-8	2003	However, Dnmt3a was fully active at physiological potassium concentration, but Dnmt3b was not.	Potassium	50-59	DNA methyltransferase 3A	Mus musculus	9-15
12611974-8	2003	Human amylin also depressed the transient outward (IA) and the delayed rectifier (IK) potassium currents.	Potassium	86-95	islet amyloid polypeptide	Homo sapiens	6-12
12795698-9	2003	This indicates that the delivery of potassium by AKT1 and the direction of assimilates, triggered by AKT2/3, are essential for tumour growth.	Potassium	36-45	K+ transporter 1	Arabidopsis thaliana	49-53
12795698-9	2003	This indicates that the delivery of potassium by AKT1 and the direction of assimilates, triggered by AKT2/3, are essential for tumour growth.	Potassium	36-45	potassium transport 2/3	Arabidopsis thaliana	101-105
12606673-0	2003	Norepinephrine evoked by potassium depolarization increases interstitial adenosine concentration via activation of ecto-5"-nucleotidase in rat hearts.	Potassium	25-34	5' nucleotidase, ecto	Rattus norvegicus	115-135
12684789-0	2003	Voltage-gated potassium currents in rat vas deferens smooth muscle cells.	Potassium	14-23	arginine vasopressin	Rattus norvegicus	40-43
12642579-3	2003	Here we show that open- and closed-state inactivation of Kv2.1 can be distinguished by the sensitivity to intracellular tetraethylammonium and extracellular potassium and lead to the same inactivated conformation.	Potassium	157-166	potassium voltage-gated channel subfamily B member 1	Homo sapiens	57-62
12729589-5	2003	Mitochondrial ATP-sensitive potassium (MitoKATP) channels modulate inner membrane potential and oxyradical production; mitochondrial potassium fluxes can affect cytochrome c release and caspase activation and may determine whether neurons live or die in experimental models of stroke and Alzheimer"s disease.	Potassium	133-142	cytochrome c, somatic	Homo sapiens	161-173
12753984-0	2003	Neurotrophin-3 modifies potassium currents in isolated inner hair cells from guinea-pig cochlea.	Potassium	24-33	neurotrophin-3	Cavia porcellus	0-14
12611901-0	2003	The K+ channel KZM1 mediates potassium uptake into the phloem and guard cells of the C4 grass Zea mays.	Potassium	29-38	potassium channel 3	Zea mays	15-19
12686415-2	2003	Here we describe a set of novel apoptotic phenomena--stimulation of the mitochondrial potassium uptake preceding cytochrome c release and regulation of such potassium uptake by bcl-2 family proteins.	Potassium	86-95	BCL2 apoptosis regulator	Homo sapiens	177-182
12856948-8	2003	We hypothesize that Zm-Mfs1 is a prototype of a new class of plant defense-related proteins that could be involved in either of three nonexclusive roles: (1) export of antimicrobial compounds produced by plant pathogens; (2) export of plant-generated antimicrobial compounds; and (3) potassium export and/or re-uptake, as can occur in plant defense reactions.	Potassium	284-293	Probable peptide/nitrate transporter At3g43790	Zea mays	23-27
12686415-2	2003	Here we describe a set of novel apoptotic phenomena--stimulation of the mitochondrial potassium uptake preceding cytochrome c release and regulation of such potassium uptake by bcl-2 family proteins.	Potassium	157-166	BCL2 apoptosis regulator	Homo sapiens	177-182
12686415-3	2003	As a result of increased potassium uptake, mitochondria undergo moderate swelling sufficient to release cytochrome c.	Potassium	25-34	cytochrome c, somatic	Homo sapiens	104-116
12686415-4	2003	Overexpression of bcl-2 protein prevented the mitochondrial potassium uptake as well as cytochrome c release in apoptosis.	Potassium	60-69	BCL2 apoptosis regulator	Homo sapiens	18-23
12686415-5	2003	Bcl-2 was found to upregulate the mitochondrial potassium efflux mechanism--the K/H exchanger.	Potassium	48-57	BCL2 apoptosis regulator	Homo sapiens	0-5
12686415-7	2003	tBid had an opposite effect-it stimulated mitochondrial potassium uptake resulting in cytochrome c release.	Potassium	56-65	cytochrome c, somatic	Homo sapiens	86-98
12686415-8	2003	The described counter-regulation of mitochondrial potassium transport by bcl-2 and Bid suggests a novel view of a mechanism of cytochrome c release from mitochondria in apoptosis.	Potassium	50-59	BCL2 apoptosis regulator	Homo sapiens	73-78
12686415-8	2003	The described counter-regulation of mitochondrial potassium transport by bcl-2 and Bid suggests a novel view of a mechanism of cytochrome c release from mitochondria in apoptosis.	Potassium	50-59	BH3 interacting domain death agonist	Homo sapiens	83-86
12686415-8	2003	The described counter-regulation of mitochondrial potassium transport by bcl-2 and Bid suggests a novel view of a mechanism of cytochrome c release from mitochondria in apoptosis.	Potassium	50-59	cytochrome c, somatic	Homo sapiens	127-139
12533541-6	2003	Co-expression of MPS-1 and KVS-1 in mammalian cells gives rise to a potassium current distinct from the KVS-1 current.	Potassium	68-77	macrophage expressed 1	Homo sapiens	17-22
12626678-4	2003	The wild-type GABA receptor was chloride selective, with a small but significant permeability to potassium (PNa+ : PK+ : PCl- = 0 : 0.03 :1).	Potassium	97-106	GABA type A receptor-associated protein	Homo sapiens	14-27
12533541-6	2003	Co-expression of MPS-1 and KVS-1 in mammalian cells gives rise to a potassium current distinct from the KVS-1 current.	Potassium	68-77	Uncharacterized protein	Caenorhabditis elegans	27-32
12611968-8	2003	Our results demonstrate that not only does ORX-A inhibit a specific potassium conductance (the sustained K(+) current) in NTS neurons, but it also activates a nonselective cationic conductance (NSCC).	Potassium	68-77	hypocretin neuropeptide precursor	Rattus norvegicus	43-46
12648746-0	2003	Neuropeptide Y modulates a G protein-coupled inwardly rectifying potassium current in the mouse hippocampus.	Potassium	65-74	neuropeptide Y	Mus musculus	0-14
12612050-0	2003	KChIP1 and frequenin modify shal-evoked potassium currents in pyloric neurons in the lobster stomatogastric ganglion.	Potassium	40-49	potassium voltage-gated channel interacting protein 1	Homo sapiens	0-6
12611922-0	2003	Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1.	Potassium	44-53	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	119-124
12514175-0	2003	Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.	Potassium	46-55	growth differentiation factor 15	Homo sapiens	0-32
12727445-4	2003	Using whole-cell and outside-out patch-clamp techniques, we observed that IL-1 beta decreased both inward sodium current amplitudes and outward potassium current amplitudes.	Potassium	144-153	interleukin 1 beta	Homo sapiens	74-83
12562917-6	2003	Of the three matrix components, only vitronectin affected potassium currents, selectively increasing the amplitude of the inactivating potassium current (IA, or A-current) by about 75 % over control levels, and its density (current per unit area) by about 40 % (measured after 3 day exposures from embryonic day 15.5).	Potassium	58-67	vitronectin	Mus musculus	37-48
12562917-6	2003	Of the three matrix components, only vitronectin affected potassium currents, selectively increasing the amplitude of the inactivating potassium current (IA, or A-current) by about 75 % over control levels, and its density (current per unit area) by about 40 % (measured after 3 day exposures from embryonic day 15.5).	Potassium	135-144	vitronectin	Mus musculus	37-48
12514175-0	2003	Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.	Potassium	46-55	AKT serine/threonine kinase 1	Homo sapiens	135-138
12514175-0	2003	Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.	Potassium	46-55	mitogen-activated protein kinase 1	Homo sapiens	143-146
12600674-1	2003	Sexual dimorphism in potassium content was found in plasma, kidney, heart and skeletal muscle of CD1 mice.	Potassium	21-30	CD1 antigen complex	Mus musculus	97-100
12600674-7	2003	However, in the male kidney potassium deficiency was accompanied by an increase of putrescine and spermidine concentration, and a reduction of putrescine excretion into the urine, even though renal K(+) concentration was not significantly affected and ornithine decarboxylase activity was dramatically decreased.	Potassium	28-37	ornithine decarboxylase, structural 1	Mus musculus	252-275
12694929-5	2003	We conclude that mGluR3 can modulate high potassium, low calcium-induced spontaneous epileptiform burst activity in acute rat hippocampal slice dentate granule cells.	Potassium	42-51	glutamate receptor, ionotropic, AMPA3 (alpha 3)	Mus musculus	17-23
14584380-1	2003	Subclinical mastitis, defined as raised milk sodium/potassium (Na/K) ratio is common and associated with poor infant growth and increased mother-to-child HIV transmission.	Potassium	52-61	TANK binding kinase 1	Homo sapiens	63-67
12693733-3	2003	Until further data from well-designed, prospective, randomized trials are available, the use of aldosterone receptor antagonists should be restricted to patients with severe or progressive heart failure caused by systolic left ventricular dysfunction in whom serum creatinine level is &lt; or = 2.0 mg/dL and serum potassium levels are &lt; 5.0 meq/L at baseline.	Potassium	315-324	nuclear receptor subfamily 3 group C member 2	Homo sapiens	96-116
12593854-4	2003	The bulk of repolarization, including the after-hyperpolarization, was sustained by the human eag related (HERG) potassium current (I(HERG)) that also governs V(REST) in 21S cells.	Potassium	113-122	potassium voltage-gated channel subfamily H member 1	Homo sapiens	94-97
12593854-4	2003	The bulk of repolarization, including the after-hyperpolarization, was sustained by the human eag related (HERG) potassium current (I(HERG)) that also governs V(REST) in 21S cells.	Potassium	113-122	potassium voltage-gated channel subfamily H member 2	Homo sapiens	107-111
12593854-4	2003	The bulk of repolarization, including the after-hyperpolarization, was sustained by the human eag related (HERG) potassium current (I(HERG)) that also governs V(REST) in 21S cells.	Potassium	113-122	potassium voltage-gated channel subfamily H member 2	Homo sapiens	134-138
12598601-2	2003	We found that elimination of the Kv3.1 gene in mice results in the loss of a high-threshold component of potassium current and failure of the neurons to follow high-frequency stimulation.	Potassium	105-114	potassium voltage gated channel, Shaw-related subfamily, member 1	Mus musculus	33-38
12598633-10	2003	Our results indicate that the steps that link acute molecular events to permanent changes in clock phase involve persistent suppression of potassium current, downstream of Per1 gene induction, in a specific subset of Per1-expressing neurons enriched for VIP.	Potassium	139-148	vasoactive intestinal peptide	Homo sapiens	254-257
12598727-1	2003	Calcium-activated potassium currents of intermediate conductance (IK1) have been described in the rodent enteric nervous system, where they may regulate afterhyperpolarisation of intrinsic primary afferent neurons.	Potassium	18-27	potassium calcium-activated channel subfamily N member 4	Homo sapiens	66-69
12529256-1	2003	Overexpression of a truncated Kv1.1 channel transgene in the heart (Kv1DN) resulted in mice with a prolonged action potential duration due to marked attenuation of a rapidly activating, slowly inactivating potassium current (I(K,slow1)) in ventricular myocytes.	Potassium	206-215	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	30-35
12582016-4	2003	In this generally well-nourished population of middle-aged to elderly men, plasma IGF-I and IGF-I:IGF-binding protein-3 molar ratio tended to increase with higher intake of protein and minerals, including potassium, zinc, magnesium, calcium, and phosphorus.	Potassium	205-214	insulin like growth factor 1	Homo sapiens	92-119
12566104-1	2003	The renaissance of glucose-insulin-potassium infusion (GIK) as a treatment of acute myocardial infarction both in diabetic and nondiabetic subjects has raised new interests to clarify the effects and mechanisms of insulin on myocardium.	Potassium	35-44	insulin	Homo sapiens	27-34
12566121-0	2003	Coordinated down-regulation of KCNQ1 and KCNE1 expression contributes to reduction of I(Ks) in canine hypertrophied hearts.	Potassium	88-90	potassium voltage-gated channel subfamily Q member 1	Canis lupus familiaris	31-36
12566121-0	2003	Coordinated down-regulation of KCNQ1 and KCNE1 expression contributes to reduction of I(Ks) in canine hypertrophied hearts.	Potassium	88-90	potassium voltage-gated channel subfamily E member 1	Canis lupus familiaris	41-46
12566121-3	2003	The present study was designed to probe the molecular basis for the decrease in I(Ks) by studying the characteristics of KCNE1 and KCNQ1, the putative genes responsible for formation of the channel.	Potassium	82-84	potassium voltage-gated channel subfamily E member 1	Canis lupus familiaris	121-126
12566121-3	2003	The present study was designed to probe the molecular basis for the decrease in I(Ks) by studying the characteristics of KCNE1 and KCNQ1, the putative genes responsible for formation of the channel.	Potassium	82-84	potassium voltage-gated channel subfamily Q member 1	Canis lupus familiaris	131-136
12566121-7	2003	CONCLUSIONS: Our results indicate that the CAVB-induced reduction in I(Ks) is due to a down-regulation of KCNE1 and KCNQ1 transcription.	Potassium	71-73	potassium voltage-gated channel subfamily E member 1	Canis lupus familiaris	106-111
12566121-7	2003	CONCLUSIONS: Our results indicate that the CAVB-induced reduction in I(Ks) is due to a down-regulation of KCNE1 and KCNQ1 transcription.	Potassium	71-73	potassium voltage-gated channel subfamily Q member 1	Canis lupus familiaris	116-121
12552520-0	2003	Ace inhibitors and survival in dialysis patients: effects on serum potassium?	Potassium	67-76	angiotensin I converting enzyme	Homo sapiens	0-3
12710526-5	2003	Potassium currents were recorded from CHO cells transfected with either wild type or mutant KCNQ1 in the presence or in the absence of its regulatory subunit (KCNE1), using the whole-cell configuration of the patch clamp technique.	Potassium	0-9	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	92-97
12710526-7	2003	Coexpressing KCNE1 with equal amount of cDNAs encoding wild type and mutant KCNQ1 results in an 11-fold reduction in the amplitude of potassium currents.	Potassium	134-143	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	13-18
12710526-7	2003	Coexpressing KCNE1 with equal amount of cDNAs encoding wild type and mutant KCNQ1 results in an 11-fold reduction in the amplitude of potassium currents.	Potassium	134-143	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	76-81
12553944-4	2003	In contrast to its sodium retaining properties in normal, obese and diabetic subjects, insulin-glucose-potassium therapy may induce a sodium diuresis in catabolic patients with salt and water overload and in patients with congestive heart failure in whom haemodynamic improvement has also been observed.	Potassium	103-112	insulin	Homo sapiens	87-94
12526027-0	2003	Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2.	Potassium	61-70	caspase 2	Homo sapiens	0-7
12554721-5	2003	Plants homozygous for the akt1-1 mutation develop longer root hairs than the wild type when grown in 0 mM external potassium, but develop shorter hairs than the wild type when grown in higher concentrations [&gt;10 mM] of potassium.	Potassium	115-124	K+ transporter 1	Arabidopsis thaliana	26-30
12554721-5	2003	Plants homozygous for the akt1-1 mutation develop longer root hairs than the wild type when grown in 0 mM external potassium, but develop shorter hairs than the wild type when grown in higher concentrations [&gt;10 mM] of potassium.	Potassium	222-231	K+ transporter 1	Arabidopsis thaliana	26-30
12554721-6	2003	These data indicate that both TRH1 and AKT1 are active in the root hair over a wide range of external potassium concentrations, but suggest they have different functions in the growing hair cell.	Potassium	102-111	Potassium transporter family protein	Arabidopsis thaliana	30-34
12554721-6	2003	These data indicate that both TRH1 and AKT1 are active in the root hair over a wide range of external potassium concentrations, but suggest they have different functions in the growing hair cell.	Potassium	102-111	K+ transporter 1	Arabidopsis thaliana	39-43
12689355-1	2003	The fast inactivation of the human ether-a-go-go related gene product (HERG) channel is a form of C-type inactivation and is decelerated by external tetraethylammonium (TEA) and potassium.	Potassium	178-187	potassium voltage-gated channel subfamily H member 2	Homo sapiens	71-75
12535075-0	2003	Characterization of potassium transport in wild-type and isogenic yeast strains carrying all combinations of trk1, trk2 and tok1 null mutations.	Potassium	20-29	Trk1p	Saccharomyces cerevisiae S288C	109-113
12535075-0	2003	Characterization of potassium transport in wild-type and isogenic yeast strains carrying all combinations of trk1, trk2 and tok1 null mutations.	Potassium	20-29	Trk2p	Saccharomyces cerevisiae S288C	115-119
12535075-0	2003	Characterization of potassium transport in wild-type and isogenic yeast strains carrying all combinations of trk1, trk2 and tok1 null mutations.	Potassium	20-29	Tok1p	Saccharomyces cerevisiae S288C	124-128
12535075-1	2003	Saccharomyces cerevisiae cells express three defined potassium-specific transport systems en-coded by TRK1, TRK2 and TOK1.	Potassium	53-62	Trk1p	Saccharomyces cerevisiae S288C	102-106
12535075-1	2003	Saccharomyces cerevisiae cells express three defined potassium-specific transport systems en-coded by TRK1, TRK2 and TOK1.	Potassium	53-62	Trk2p	Saccharomyces cerevisiae S288C	108-112
12535075-1	2003	Saccharomyces cerevisiae cells express three defined potassium-specific transport systems en-coded by TRK1, TRK2 and TOK1.	Potassium	53-62	Tok1p	Saccharomyces cerevisiae S288C	117-121
12535075-4	2003	As has been reported previously, Trk1p and Trk2p facilitate high-affinity potassium uptake and appear to be functionally redundant under a wide range of environmental conditions.	Potassium	74-83	Trk1p	Saccharomyces cerevisiae S288C	33-38
12535075-4	2003	As has been reported previously, Trk1p and Trk2p facilitate high-affinity potassium uptake and appear to be functionally redundant under a wide range of environmental conditions.	Potassium	74-83	Trk2p	Saccharomyces cerevisiae S288C	43-48
12526027-4	2003	Cerebellar granule cells (CGCs) undergo apoptosis when they are transferred from high potassium (K25) to low potassium (K5); this process seems to be mediated by caspase-3 activation.	Potassium	86-95	caspase 3	Homo sapiens	162-171
12526027-4	2003	Cerebellar granule cells (CGCs) undergo apoptosis when they are transferred from high potassium (K25) to low potassium (K5); this process seems to be mediated by caspase-3 activation.	Potassium	109-118	caspase 3	Homo sapiens	162-171
12685554-2	2003	Point mutations on the human skeletal muscle Na+ channel (Nav1.4) give rise to hyperkalemic periodic paralysis, potassium aggravated myotonia, paramyotonia congenita and hypokalemic periodic paralysis type 2.	Potassium	112-121	sodium voltage-gated channel alpha subunit 4	Homo sapiens	58-64
12525183-1	2003	The Na/Ca-K exchanger (NCKX) utilizes the inward sodium gradient and outward potassium gradient for Ca(2+) extrusion; two distinct NCKX isoforms are expressed in the outer segments of retinal rod (NCKX1) and cone (NCKX2) photoreceptors, respectively, where NCKX extrudes Ca(2+) that enters photoreceptors via the cGMP-gated channels.	Potassium	77-86	solute carrier family 24 member 1	Homo sapiens	23-27
12525183-1	2003	The Na/Ca-K exchanger (NCKX) utilizes the inward sodium gradient and outward potassium gradient for Ca(2+) extrusion; two distinct NCKX isoforms are expressed in the outer segments of retinal rod (NCKX1) and cone (NCKX2) photoreceptors, respectively, where NCKX extrudes Ca(2+) that enters photoreceptors via the cGMP-gated channels.	Potassium	77-86	solute carrier family 24 member 1	Homo sapiens	197-202
12610977-1	2003	In the presence of ionising radiation, an aza-18-crown-6 molecule covalently attached to a 2,5-diphenyloxazole (PPO) moiety scintillates weakly, addition of potassium ions results in enhanced levels of scintillation, the degree of scintillation reflecting the concentration of the potassium ions.	Potassium	157-166	protoporphyrinogen oxidase	Homo sapiens	112-115
12610977-1	2003	In the presence of ionising radiation, an aza-18-crown-6 molecule covalently attached to a 2,5-diphenyloxazole (PPO) moiety scintillates weakly, addition of potassium ions results in enhanced levels of scintillation, the degree of scintillation reflecting the concentration of the potassium ions.	Potassium	281-290	protoporphyrinogen oxidase	Homo sapiens	112-115
14621405-4	2003	Although Norwegian scientists presented evidence of a role for cations and anions in milk fever during the late 1960"s, recent studies have more precisely defined the physiological link between high diet potassium and tissue sensitivity to parathyroid hormone as a leading cause of milk fever.	Potassium	204-213	parathyroid hormone	Bos taurus	240-259
12573695-5	2003	Most PBGS that do not require zinc require magnesium and/or potassium instead.	Potassium	60-69	aminolevulinate dehydratase	Homo sapiens	5-9
12595961-0	2003	Somatostatin inhibits potassium-evoked glutamate release by activation of the sst(2) somatostatin receptor in the mouse retina.	Potassium	22-31	somatostatin	Mus musculus	0-12
12595961-0	2003	Somatostatin inhibits potassium-evoked glutamate release by activation of the sst(2) somatostatin receptor in the mouse retina.	Potassium	22-31	somatostatin	Homo sapiens	85-97
14763661-7	2003	Angiotensin II in plasma and urine excretion of potassium were higher among Greenlanders compared with Danes, irrespective of diet and place of residence.	Potassium	48-57	angiotensinogen	Homo sapiens	0-14
12459913-2	2003	The PBGS protein sequence contains a unique metal switch region that has been postulated to dictate an exclusive catalytic use of either zinc or magnesium, and perhaps also potassium.	Potassium	173-182	aminolevulinate dehydratase	Homo sapiens	4-8
12506133-8	2003	Potassium secretion in the CCD is tightly linked to sodium reabsorption through EnaC; therefore, NM-induced decrease in prostasin secretion and subsequent inhibition of ENaC activity could account for the side effects of hyponatremia and/or hyperkalemia that are found sometimes in patients treated with NM.	Potassium	0-9	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	80-84
12506133-8	2003	Potassium secretion in the CCD is tightly linked to sodium reabsorption through EnaC; therefore, NM-induced decrease in prostasin secretion and subsequent inhibition of ENaC activity could account for the side effects of hyponatremia and/or hyperkalemia that are found sometimes in patients treated with NM.	Potassium	0-9	serine protease 8	Homo sapiens	120-129
12459913-3	2003	In some PBGS, the cysteines of the metal switch sequence DXCXCX(Y/F)X(3)G(H/Q)CG have been demonstrated to bind a catalytic zinc, and in other PBGS, the aspartic acid residues of the metal switch sequence DXALDX(Y/F)X(3)G(H/Q)DG have been postulated to bind a catalytically essential magnesium and/or potassium.	Potassium	301-310	aminolevulinate dehydratase	Homo sapiens	8-12
12459913-3	2003	In some PBGS, the cysteines of the metal switch sequence DXCXCX(Y/F)X(3)G(H/Q)CG have been demonstrated to bind a catalytic zinc, and in other PBGS, the aspartic acid residues of the metal switch sequence DXALDX(Y/F)X(3)G(H/Q)DG have been postulated to bind a catalytically essential magnesium and/or potassium.	Potassium	301-310	aminolevulinate dehydratase	Homo sapiens	143-147
12459913-5	2003	The resultant chimeric PBGS proteins, peainhuman PBGS and psuinhuman PBGS, are substantially activated by both magnesium and potassium, but not by zinc.	Potassium	125-134	aminolevulinate dehydratase	Homo sapiens	23-27
12459913-5	2003	The resultant chimeric PBGS proteins, peainhuman PBGS and psuinhuman PBGS, are substantially activated by both magnesium and potassium, but not by zinc.	Potassium	125-134	aminolevulinate dehydratase	Homo sapiens	49-53
12459913-5	2003	The resultant chimeric PBGS proteins, peainhuman PBGS and psuinhuman PBGS, are substantially activated by both magnesium and potassium, but not by zinc.	Potassium	125-134	aminolevulinate dehydratase	Homo sapiens	49-53
12767264-6	2003	Alteration of the membrane potassium gradient modulates the respiratory burst of unstimulated and CR3-activated cells, whilst it does not seem to significantly interfere with the signals delivered by FcgammaR.	Potassium	27-36	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	98-101
14646359-2	2003	Our results indicate the existence of a clear sexual dimorphism in renal and plasma potassium content in CD1 mice, adult males having a higher plasma potassium concentration than females or 40-day-old male mice (4.6 +/- 1.0 vs. 3.9 +/- 0.9 mEq/l).	Potassium	84-93	CD1 antigen complex	Mus musculus	105-108
14622907-0	2003	Transforming growth factor-alpha changes firing properties of developing neocortical GABAergic neurons by down-regulation of voltage-gated potassium currents.	Potassium	139-148	tumor necrosis factor	Homo sapiens	0-32
12595240-7	2003	Depolarization of PC12 cells with high potassium triggers colocalization of CgB and TGF-beta2 at the cell surface, suggesting their regulated corelease from secretory granules.	Potassium	39-48	chromogranin B	Rattus norvegicus	76-79
12595240-7	2003	Depolarization of PC12 cells with high potassium triggers colocalization of CgB and TGF-beta2 at the cell surface, suggesting their regulated corelease from secretory granules.	Potassium	39-48	transforming growth factor, beta 2	Rattus norvegicus	84-93
12595240-8	2003	High potassium also liberates biologically active TGF-beta from PC12 cells and primary neurons.	Potassium	5-14	transforming growth factor, beta 1	Rattus norvegicus	50-58
12676137-0	2003	Vascular endothelial growth factor inhibits outward delayed-rectifier potassium currents in acutely isolated hippocampal neurons.	Potassium	70-79	vascular endothelial growth factor A	Rattus norvegicus	0-34
12862247-0	2003	Measurement of 40k as an indicator of body potassium: implication for diabetes and other disease conditions.	Potassium	43-52	small nuclear ribonucleoprotein U5 subunit 40	Homo sapiens	15-18
14622907-8	2003	Voltage-clamp recordings from the bipolar neurons indicated that chronic treatment with TGFalpha markedly decreased the current densities of slow delayed rectifier (IK) and transient voltage-gated potassium currents, whereas the treatment had no effect on voltage-gated sodium current and fast delayed rectifier potassium current densities.	Potassium	197-206	transforming growth factor alpha	Homo sapiens	88-96
14622907-10	2003	Thus, chronic treatment with TGFalpha down-regulated slow delayed rectifier and transient voltage-gated potassium currents, and in parallel, suppressed repetitive generation of action potentials in the cortical GABAergic neurons.	Potassium	104-113	transforming growth factor alpha	Homo sapiens	29-37
12499920-7	2003	Moreover, although the insulin response to high glucose and potassium loading was maintained, the magnitude of the responses to both stimuli was attenuated in the late period of culture.	Potassium	60-69	insulin	Homo sapiens	23-30
12445880-5	2002	METHODS: We investigated the effects of beta(1)- and beta(3)-adrenoceptor modulation on I(Ks) in guinea-pig ventricular myocytes, using patch-clamp techniques.	Potassium	90-92	beta-3 adrenergic receptor	Cavia porcellus	53-73
12482884-10	2002	The slowing of I(KS) deactivation produced by low pH(o) was absent in the KCNE1 mutant Delta39-43, suggesting that the residues lying at the N-terminal boundary of the transmembrane segment are involved in this process.	Potassium	17-19	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	74-79
12379639-0	2002	Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4.	Potassium	44-53	solute carrier family 24 member 4	Homo sapiens	102-107
12388387-0	2002	Altered expression of renal NHE3, TSC, BSC-1, and ENaC subunits in potassium-depleted rats.	Potassium	67-76	solute carrier family 9 member A3	Rattus norvegicus	28-32
12388387-0	2002	Altered expression of renal NHE3, TSC, BSC-1, and ENaC subunits in potassium-depleted rats.	Potassium	67-76	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	50-54
12763066-8	2003	muOR internalization was prevented by hyperosmolar sucrose, phenylarsine oxide or potassium depletion, which inhibit clathrin-mediated endocytosis.	Potassium	82-91	mu-type opioid receptor	Cavia porcellus	0-4
12763069-0	2003	Prostaglandin E2 inhibits the potassium current in sensory neurons from hyperalgesic Kv1.1 knockout mice.	Potassium	30-39	potassium voltage-gated channel, shaker-related subfamily, member 1	Mus musculus	85-90
12489809-0	2002	Potassium-induced increase in renal kallikrein secretion is attenuated in dissected renal connecting tubules of young spontaneously hypertensive rats.	Potassium	0-9	kallikrein 1	Rattus norvegicus	30-46
12489809-6	2002	Augmentation of renal kallikrein secretion by potassium or PNU-37883A was diminished in SHR compared to WKY.	Potassium	46-55	kallikrein 1	Rattus norvegicus	16-32
12489809-7	2002	These results indicate that the ability to secrete renal kallikrein by potassium was attenuated in young SHR compared with WKY.	Potassium	71-80	kallikrein 1	Rattus norvegicus	51-67
12489809-8	2002	Furthermore, it is suggested that the potassium-induced renal kallikrein secretion requires an extracellular Ca2+ entry through Ca2+ channels including L-type Ca2+ channels and Ca2+ release from intracellular Ca2+ stores through IP3 receptor and ryanodine receptor.	Potassium	38-47	kallikrein 1	Rattus norvegicus	56-72
12451111-0	2002	Potassium currents during the action potential of hippocampal CA3 neurons.	Potassium	0-9	carbonic anhydrase 3	Homo sapiens	62-65
12451111-2	2002	We characterized the voltage-dependent potassium currents flowing during the action potentials of hippocampal CA3 pyramidal neurons and examined the susceptibility of the underlying channel types to inactivation at subthreshold voltages.	Potassium	39-48	carbonic anhydrase 3	Homo sapiens	110-113
12435606-6	2002	Co-expression of PSD95 with Kv1.5 N- and C-terminal deletions in HEK cells had contrasting effects on the magnitudes of the potassium currents across the membranes of these cells.	Potassium	124-133	discs large MAGUK scaffold protein 4	Homo sapiens	17-22
12435606-6	2002	Co-expression of PSD95 with Kv1.5 N- and C-terminal deletions in HEK cells had contrasting effects on the magnitudes of the potassium currents across the membranes of these cells.	Potassium	124-133	potassium voltage-gated channel subfamily A member 5	Homo sapiens	28-33
12397014-8	2002	Using an immunoassay to quantitate 5HT secretion, we also show that downregulation of CFTR abolishes hypoxia-induced 5HT release, and reduces secretory response to high potassium.	Potassium	169-178	CF transmembrane conductance regulator	Homo sapiens	86-90
12372765-1	2002	The H(+)-K(+)-ATPase alpha(2) (HKalpha(2)) gene plays a central role in potassium homeostasis, yet little is known about its transcriptional control.	Potassium	72-81	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	4-29
12372765-1	2002	The H(+)-K(+)-ATPase alpha(2) (HKalpha(2)) gene plays a central role in potassium homeostasis, yet little is known about its transcriptional control.	Potassium	72-81	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	31-41
12463096-9	2002	Multivariate analysis suggested that NKA-Abs was an independent risk factor for the occurrence of paroxysmal atrial fibrillation (p &lt; 0.01), although there were no differences in other clinical factors: age, sex, New York Heart Association functional class, concomitant medication, left ventricular ejection fraction, left atrial diameter, severity of mitral regurgitation, serum potassium, plasma norepinephrine, and atrial natriuretic peptide concentration.	Potassium	383-392	tachykinin precursor 1	Homo sapiens	37-40
12463620-5	2002	Glucose-insulin-potassium protocol consisted of a fixed dose of insulin (100 microU/kg/hour IV) and a variable glucose/potassium infusion rate.	Potassium	16-25	insulin	Homo sapiens	8-15
12500569-7	2002	The N,N"-dicyclohexylcarbodiimide (DCCD)-sensitive ATPase activity increased 2.5 times as K+ concentration increased to 100 mM (including residual K+ in potassium-free medium).	Potassium	153-162	ATPase	Escherichia coli	51-57
12411468-7	2002	The increase in plasma potassium levels elicited by COX-2 inhibition was greater in dogs with low sodium intake and was enhanced when NO production was inhibited.	Potassium	23-32	prostaglandin-endoperoxide synthase 2	Canis lupus familiaris	52-57
12411468-9	2002	The results of this study suggest that COX-2-derived metabolites (1) play a more important role in the long-term regulation of renal hemodynamic when sodium intake is low, (2) protect the renal vasculature from the vasoconstriction secondary to a reduction in NO, (3) are only acutely involved in regulating urinary sodium excretion, and (4) play a more important role in regulating plasma potassium concentration when NO synthesis is reduced.	Potassium	390-399	prostaglandin-endoperoxide synthase 2	Canis lupus familiaris	39-44
12427859-7	2002	An outward potassium current, recorded with the patch-clamp technique, was inhibited by exogenous application of sulfated cholecystokinin octapeptide in a reversible and concentration-dependent manner.	Potassium	11-20	cholecystokinin	Rattus norvegicus	122-137
12427859-9	2002	An inwardly rectifying potassium current, typically invariant to stimulation, was also inhibited by cholecystokinin.	Potassium	23-32	cholecystokinin	Rattus norvegicus	100-115
12367768-12	2002	In Northeast Thailand, low potassium status and a high carbohydrate and low fat diet may cause the increased ACL activity.	Potassium	27-36	ATP citrate lyase	Homo sapiens	109-112
12381810-1	2002	The ROMK subtypes of inward-rectifier K(+) channels mediate potassium secretion and regulate NaCl reabsorption in the kidney.	Potassium	60-69	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	4-8
12417654-4	2002	IGF-I blocked activation of the executioner caspase-3 and the intrinsic initiator caspase-9 in primary cerebellar granule neurons deprived of serum and depolarizing potassium.	Potassium	165-174	insulin like growth factor 1	Homo sapiens	0-5
12417654-4	2002	IGF-I blocked activation of the executioner caspase-3 and the intrinsic initiator caspase-9 in primary cerebellar granule neurons deprived of serum and depolarizing potassium.	Potassium	165-174	caspase 3	Homo sapiens	44-53
12417654-4	2002	IGF-I blocked activation of the executioner caspase-3 and the intrinsic initiator caspase-9 in primary cerebellar granule neurons deprived of serum and depolarizing potassium.	Potassium	165-174	caspase 9	Homo sapiens	82-91
12961001-14	2002	In patients with SEH, EPO correlated positively with potassium concentration and 24-hour microalbuminuria (r=0.574 and r=0.465, respectively).	Potassium	53-62	erythropoietin	Homo sapiens	22-25
12381813-8	2002	In addition, NGF and ceramide suppressed an outward potassium current (I(K)) by approximately 35 %.	Potassium	52-61	nerve growth factor	Rattus norvegicus	13-16
12145295-6	2002	Lentivirus-induced overexpression of A53T mutant alpha-synuclein in differentiated MESC2.10 cells resulted in down-regulation of the vesicular dopamine transporter (VMAT2), decreased potassium-induced and increased amphetamine-induced dopamine release, enhanced cytoplasmic dopamine immunofluorescence, and increased intracellular levels of superoxide.	Potassium	183-192	synuclein alpha	Homo sapiens	49-64
12381814-0	2002	Contribution of Kv4 channels toward the A-type potassium current in murine colonic myocytes.	Potassium	47-56	potassium voltage gated channel, Shaw-related subfamily, member 1	Mus musculus	16-19
12388591-11	2002	Instead, in many cases the orexin A-induced current reversed in calcium-free medium at a value (-23 mV) consistent with the activation of a mixed cation channel (with relative permeabilities for sodium and potassium of 0.43 and 1, respectively).	Potassium	206-215	hypocretin	Mus musculus	27-35
12237170-0	2002	Cardiac-enriched LIM domain protein fhl2 is required to generate I(Ks) in a heterologous system.	Potassium	67-69	four and a half LIM domains protein 2	Cricetulus griseus	36-40
12237170-7	2002	By contrast, in CHO-K1 cells, which express fhl2 endogenously, I(Ks) was suppressed by anti-fhl2 antisense which did not affect the currents generated by KvLQT1alone.	Potassium	65-67	four and a half LIM domains protein 2	Cricetulus griseus	44-48
12237170-7	2002	By contrast, in CHO-K1 cells, which express fhl2 endogenously, I(Ks) was suppressed by anti-fhl2 antisense which did not affect the currents generated by KvLQT1alone.	Potassium	65-67	four and a half LIM domains protein 2	Cricetulus griseus	92-96
12398773-5	2002	Adequate attention should be given to maintaining euglycemia (plasma glucose &lt;or= 110 mg/dl) in order to reduce infarct size and improve cardiac function while using a glucose-insulin-potassium cocktail.	Potassium	187-196	insulin	Homo sapiens	179-186
12183334-11	2002	Additionally, in a cell line expressing both the glucocorticoid intracellular receptor and recombinant, fast inactivating potassium channels (hKv1.3), cortisol (1 and 10 microM) inhibited potassium currents by shifting their steady-state activation curves to the right by 12 mV (10 microM cortisol).	Potassium	122-131	potassium voltage-gated channel subfamily A member 3	Homo sapiens	142-148
12491724-5	2002	The simplified formula is theta = 1.1(1/beta-1) (Ks + S)/KX0, for petrochemical wastewater treatment K and Ks equaled 0.185 and 154.2, respectively.	Potassium	49-51	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	40-47
12491724-5	2002	The simplified formula is theta = 1.1(1/beta-1) (Ks + S)/KX0, for petrochemical wastewater treatment K and Ks equaled 0.185 and 154.2, respectively.	Potassium	107-109	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	40-47
12412921-5	2002	Serum IGF-I concentration increased relative to almost undetectable levels (1 ng/mL) of controls to 216 +/- 59 ng/mL at 20 min after IGF-I injection (P &lt; 0.001) and decreased to 12 +/- 6 ng/ mL by 6 h. Serum glucose and nonprotein nitrogen concentrations were significantly decreased for all or most of the 3 h after IGF-I injection, respectively, but only glucose concentration was the same as controls by 6 h. Low serum glucose and nonprotein nitrogen during the first few hours after IGF-I injection may contribute to the inhibition of Ks at 2.5 h, but the mechanisms behind the increased Ks at 6 h are not clear.	Potassium	542-544	insulin like growth factor 1	Homo sapiens	6-11
12412921-5	2002	Serum IGF-I concentration increased relative to almost undetectable levels (1 ng/mL) of controls to 216 +/- 59 ng/mL at 20 min after IGF-I injection (P &lt; 0.001) and decreased to 12 +/- 6 ng/ mL by 6 h. Serum glucose and nonprotein nitrogen concentrations were significantly decreased for all or most of the 3 h after IGF-I injection, respectively, but only glucose concentration was the same as controls by 6 h. Low serum glucose and nonprotein nitrogen during the first few hours after IGF-I injection may contribute to the inhibition of Ks at 2.5 h, but the mechanisms behind the increased Ks at 6 h are not clear.	Potassium	595-597	insulin like growth factor 1	Homo sapiens	6-11
12231642-4	2002	Markedly augmented c-Fos expression was also observed under Na(+)-K(+) pump inhibition in potassium-depleted medium.	Potassium	90-99	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	19-24
12231642-9	2002	Augmented c-Fos expression was also observed under VSMC depolarization in high-potassium medium.	Potassium	79-88	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	10-15
12148092-1	2002	Evaluation of candidate loci culminated in the identification of a heterozygous missense mutation (R67W) in KCNJ2, the gene encoding the inward-rectifying potassium current, Kir2.1, in 41 members of a kindred in which ventricular arrhythmias (13 of 16 female members [81%]) and periodic paralysis (10 of 25 male members [40%]) segregated as autosomal dominant traits with sex-specific variable expressivity.	Potassium	155-164	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	108-113
12148092-1	2002	Evaluation of candidate loci culminated in the identification of a heterozygous missense mutation (R67W) in KCNJ2, the gene encoding the inward-rectifying potassium current, Kir2.1, in 41 members of a kindred in which ventricular arrhythmias (13 of 16 female members [81%]) and periodic paralysis (10 of 25 male members [40%]) segregated as autosomal dominant traits with sex-specific variable expressivity.	Potassium	155-164	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	174-180
12421568-1	2002	Interleukin-1 (IL-1) is a multifunctional cytokine known to act as a growth factor for AIDS-KS cells.	Potassium	92-94	interleukin 1 alpha	Homo sapiens	0-13
12421568-1	2002	Interleukin-1 (IL-1) is a multifunctional cytokine known to act as a growth factor for AIDS-KS cells.	Potassium	92-94	interleukin 1 alpha	Homo sapiens	15-19
12421568-2	2002	In addition to its mitogenic effects, we found that IL-1 induced the protection of KS cells from apoptotic death induced by serum deprivation in a dose-dependent manner.	Potassium	83-85	interleukin 1 alpha	Homo sapiens	52-56
12421568-3	2002	AIDS-KS cells as well as cells derived from iatrogenic and sporadic KS exhibited a similar response to IL-1, which stresses the key role of this cytokine in the pathogenesis of KS regardless of its epidemiological form.	Potassium	5-7	interleukin 1 alpha	Homo sapiens	103-107
12421568-5	2002	The effects of IL-1 were inhibited by IL-1ra, suggesting that imbalance between these two counter-acting cytokines may contribute to the altered accumulation of KS spindle cells.	Potassium	161-163	interleukin 1 alpha	Homo sapiens	15-19
12421568-5	2002	The effects of IL-1 were inhibited by IL-1ra, suggesting that imbalance between these two counter-acting cytokines may contribute to the altered accumulation of KS spindle cells.	Potassium	161-163	interleukin 1 receptor antagonist	Homo sapiens	38-44
12015312-1	2002	Inappropriate activation of the mineralocorticoid receptor (MR) results in renal sodium retention and potassium loss in patients with liver cirrhosis.	Potassium	102-111	nuclear receptor subfamily 3 group C member 2	Homo sapiens	32-58
12196481-0	2002	The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.	Potassium	43-52	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	75-81
12196481-2	2002	The relevance to type 2 diabetes of the common polymorphism Glu23Lys in the potassium inward rectifier 6.2 (KIR6.2) gene is still controversial.	Potassium	76-85	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	108-114
12359151-4	2002	Acute application of BDNF significantly increased potassium-stimulated release of GABA in the dorsal horn isolated in vitro and this effect was blocked by K-252a.	Potassium	50-59	brain-derived neurotrophic factor	Rattus norvegicus	21-25
12101003-0	2002	Molecular analysis of the mechanism of potassium uptake through the TRK1 transporter of Saccharomyces cerevisiae.	Potassium	39-48	Trk1p	Saccharomyces cerevisiae S288C	68-72
12034739-4	2002	Our data indicate that TGF-beta type I receptor is endocytosed via a clathrin-dependent mechanism and is effectively blocked by depletion of intracellular potassium or by expression of a mutant dynamin (K44A).	Potassium	155-164	transforming growth factor beta receptor 1	Homo sapiens	23-47
12016229-4	2002	Recent kinetic studies indicate that potassium functionally compensates for the absence of the second lysine in the human tyrosyl-tRNA synthetase (222KKSSS226).	Potassium	37-46	tyrosyl-tRNA synthetase 1	Homo sapiens	122-145
12198388-5	2002	We also used microdialysis to measure basal and potassium-stimulated acetylcholine (ACh) release in the CA1 region of the hippocampus.	Potassium	48-57	carbonic anhydrase 1	Mus musculus	104-107
12167797-6	2002	RESULTS: In group I, 20-mmol/L potassium ion greatly reduced the bradykinin-induced relaxation (35.0% +/- 4.9% vs 86.0% +/- 5.3%, P &lt;.001), which was significantly restored by magnesium ion (51.9% +/- 4.0%, P =.017).	Potassium	31-40	kininogen 1	Homo sapiens	65-75
12167797-8	2002	In group IV, potassium ion depolarized the smooth muscle and decreased the bradykinin-induced hyperpolarization (-72.0 +/- 1.5 vs -61.7 +/- 0.7 mV, n = 7, P &lt;.001), which was significantly restored by magnesium ion (-68.0 +/- 2.5 mV vs -72.5 +/- 1.5 mV, n = 6, P =.029).	Potassium	13-22	kininogen 1	Homo sapiens	75-85
12015312-7	2002	In conclusion, these findings indicate that CDCA, and to a lesser extent DCA, by inhibiting 11 beta HSD2, mediate cortisol-dependent nuclear translocation and transcriptional activation of MR and are responsible at least for a part of the sodium retention and potassium excretion observed in patients with biliary obstruction.	Potassium	260-269	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	92-104
12141411-4	2002	Rofecoxib, a specific COX 2 inhibitor, promptly elevated serum potassium concentration with normalization of plasma aldosterone and near normalization of renin without a change in serum magnesium.	Potassium	63-72	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	22-27
12167275-4	2002	The geometric mean serum VEGF concentration was 81.5 pg/ml in those with AIDS-KS and 80.4 pg/ml in those with AIDS but without KS.	Potassium	78-80	vascular endothelial growth factor A	Homo sapiens	25-29
12172639-3	2002	The major potassium current components were mediated by outward rectifying ether a go-go (hEAG) channels and Ca2+-activated channels (KCa) of the IK/SK type.	Potassium	10-19	potassium voltage-gated channel subfamily H member 1	Homo sapiens	90-94
12172639-3	2002	The major potassium current components were mediated by outward rectifying ether a go-go (hEAG) channels and Ca2+-activated channels (KCa) of the IK/SK type.	Potassium	10-19	casein kappa	Homo sapiens	134-137
11980904-10	2002	The reduction in current amplitudes and the accelerated inactivation of dephosphorylated Eag channels would result in decreased outward potassium currents and hyperexcitability at presynaptic terminals and, thus, are consistent with the NMJ phenotype observed when CaMKII is inhibited.	Potassium	136-145	ether a go-go	Drosophila melanogaster	89-92
11980904-10	2002	The reduction in current amplitudes and the accelerated inactivation of dephosphorylated Eag channels would result in decreased outward potassium currents and hyperexcitability at presynaptic terminals and, thus, are consistent with the NMJ phenotype observed when CaMKII is inhibited.	Potassium	136-145	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	265-271
12358141-7	2002	SBP and DBP tended to be negatively associated with 24 h urinary potassium (K) and magnesium (Mg) excretion.	Potassium	65-74	selenium binding protein 1	Homo sapiens	0-3
12358141-7	2002	SBP and DBP tended to be negatively associated with 24 h urinary potassium (K) and magnesium (Mg) excretion.	Potassium	65-74	D-box binding PAR bZIP transcription factor	Homo sapiens	8-11
12150340-10	2002	There was a significant negative correlation between plasma AVP and serum potassium levels (r=-0.71; p&lt;0.001).	Potassium	74-83	arginine vasopressin	Homo sapiens	60-63
12092742-0	2002	Comparative effects on dynamic renal potassium excretion of ACE inhibition versus angiotensin receptor blockade in hypertensive patients with type II diabetes mellitus.	Potassium	37-46	angiotensin I converting enzyme	Homo sapiens	60-63
12096059-1	2002	Brief pressure ejection of solutions containing potassium, caesium or rubidium ions into stratum radiatum of the CA1 or CA3 regions of the hippocampal slice evoked a fast network oscillation.	Potassium	48-57	carbonic anhydrase 1	Rattus norvegicus	113-116
12065733-2	2002	To clarify the underlying ionic mechanisms, we examined the effects of six macrolides on the human ether-a-go-go-related gene (HERG)-encoded potassium current stably expressed in human embryonic kidney-293 cells.	Potassium	141-150	potassium voltage-gated channel subfamily H member 2	Homo sapiens	127-131
12096059-1	2002	Brief pressure ejection of solutions containing potassium, caesium or rubidium ions into stratum radiatum of the CA1 or CA3 regions of the hippocampal slice evoked a fast network oscillation.	Potassium	48-57	carbonic anhydrase 3	Rattus norvegicus	120-123
12031545-2	2002	BDNF potentiated the potassium or veratrine-stimulated release of GABA, dopamine and serotonin.	Potassium	21-30	brain-derived neurotrophic factor	Rattus norvegicus	0-4
12068032-7	2002	The reductions in the maximal potassium conductance produced by antisense Kvbeta2 treatment and elimination of Kv1alpha subunit function were not significantly different from each other.	Potassium	30-39	potassium channel, voltage gated subfamily A regulatory beta subunit 2 L homeolog	Xenopus laevis	74-81
12051693-3	2002	A truncated isoform of KCNQ1 was reported to be expressed physiologically and to suppress a delayed rectifier potassium current dominant-negatively in human heart.	Potassium	110-119	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	23-28
12051693-9	2002	When this gene was expressed along with a full-length KCNQ1, it suppressed potassium currents, whether a regulatory subunit minK was co-expressed or not.	Potassium	75-84	potassium voltage-gated channel subfamily Q member 1	Rattus norvegicus	54-59
12051705-0	2002	PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neurons.	Potassium	38-47	polyglutamine binding protein 1	Homo sapiens	0-6
12051705-5	2002	Our results indicate that overexpression of PQBP-1 inhibits the basal transcription in cerebellar neurons and increases their vulnerability to low potassium conditions.	Potassium	147-156	polyglutamine binding protein 1	Homo sapiens	44-50
12095095-7	2002	The cells from the patient displayed strong downregulation of inwardly rectifying potassium ion (Kir) currents (mean 0.41 [SD 0.24] pA/pF, compared to 3.43 [SD 1.86] pA/pF for the control cells).	Potassium	82-91	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	97-100
12033911-6	2002	In [K(1,10-diaza-18-crown-6)][cis-IrH(4)(PPh(3))(2)], the potassium bonds to two hydrides so that one NH can form an intra-ion-pair protonic-hydridic hydrogen bond while the other forms an inter-ion-pair NH.HIr hydrogen bond to form chains through the lattice.	Potassium	58-67	caveolin 1	Homo sapiens	41-47
11927599-0	2002	Potassium functionally replaces the second lysine of the KMSKS signature sequence in human tyrosyl-tRNA synthetase.	Potassium	0-9	tyrosyl-tRNA synthetase 1	Homo sapiens	91-114
11927599-4	2002	Equilibrium dialysis and pre-steady-state kinetic analyses were used to determine the role that potassium plays in the tyrosine activation reaction in the human tyrosyl-tRNA synthetase and whether it can be replaced by any of the other alkali metals.	Potassium	96-105	tyrosyl-tRNA synthetase 1	Homo sapiens	161-184
11927599-6	2002	Potassium also appears to stabilize the asymmetric conformation of the human tyrosyl-tRNA synthetase dimer by 0.7 kcal/mol.	Potassium	0-9	tyrosyl-tRNA synthetase 1	Homo sapiens	77-100
12040037-3	2002	Such asymmetric and clustered distribution of Kir4.1 channels in Muller cells is thought to be critical for the buffering of extracellular potassium concentration in retina.	Potassium	139-148	potassium inwardly-rectifying channel, subfamily J, member 10	Mus musculus	46-52
12111247-0	2002	Inwardly rectifying potassium currents in rat basophilic leukaemia (RBL-1) cells: regulation by spermine and implications for store-operated calcium influx.	Potassium	20-29	RB transcriptional corepressor like 1	Rattus norvegicus	68-73
12134182-0	2002	Endogenous sodium-potassium ATPase inhibition related biochemical cascade in trisomy 21 and Huntington"s disease: neural regulation of genomic function.	Potassium	18-27	dynein axonemal heavy chain 8	Homo sapiens	28-34
12111247-4	2002	Here we investigated inwardly rectifying potassium currents ( I(RK)) in rat basophilic leukaemia (RBL-1) cells, a model system for studying store-operated Ca(2+) influx.	Potassium	41-50	RB transcriptional corepressor like 1	Rattus norvegicus	98-103
11893737-0	2002	Specific modulation of Kex2/furin family proteases by potassium.	Potassium	54-63	furin, paired basic amino acid cleaving enzyme	Homo sapiens	28-33
11875062-8	2002	We demonstrate that internalized lipoplexes colocalize with transferrin in early endocytic compartments and that lipoplex internalization is inhibited in potassium-depleted cells and in cells overexpressing dominant negative Eps15 mutants.	Potassium	154-163	epidermal growth factor receptor pathway substrate 15	Homo sapiens	225-230
12186749-4	2002	On the contrary erythrocyte potassium was significantly higher (p&lt;0.01) in PIH women as compared to normotensive pregnant women.	Potassium	28-37	pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included)	Homo sapiens	78-81
11893737-7	2002	In contrast, the neuroendocrine homolog PC2 is inhibited by potassium ion with all substrates examined.	Potassium	60-69	proprotein convertase subtilisin/kexin type 2	Homo sapiens	40-43
11893737-9	2002	These biochemical data indicate that potassium ion concentration may function as a regulator of processing protease specificity and activity in the eukaryotic secretory pathway, with such enzymes potentially encountering compartments high in potassium ion caused by the action of antiporters such as yeast NHX1 (VPS44) or the mammalian NHE7.	Potassium	37-46	bifunctional K:H/Na:H antiporter NHX1	Saccharomyces cerevisiae S288C	306-310
11893737-9	2002	These biochemical data indicate that potassium ion concentration may function as a regulator of processing protease specificity and activity in the eukaryotic secretory pathway, with such enzymes potentially encountering compartments high in potassium ion caused by the action of antiporters such as yeast NHX1 (VPS44) or the mammalian NHE7.	Potassium	37-46	bifunctional K:H/Na:H antiporter NHX1	Saccharomyces cerevisiae S288C	312-317
11893737-9	2002	These biochemical data indicate that potassium ion concentration may function as a regulator of processing protease specificity and activity in the eukaryotic secretory pathway, with such enzymes potentially encountering compartments high in potassium ion caused by the action of antiporters such as yeast NHX1 (VPS44) or the mammalian NHE7.	Potassium	37-46	solute carrier family 9 member A7	Homo sapiens	336-340
12133532-9	2002	The coupling between the repolarizing cardiac HERG potassium current and the protein kinase A system could contribute to arrhythmogenesis under pathophysiological conditions.	Potassium	51-60	potassium voltage-gated channel subfamily H member 2	Homo sapiens	46-50
12015417-0	2002	Molecular determinants of the inhibition of human Kv1.5 potassium currents by external protons and Zn(2+).	Potassium	56-65	potassium voltage-gated channel subfamily A member 5	Homo sapiens	50-55
11988490-5	2002	(3) Alterations of I(Ks), I(Kr), and I(Na) (fast sodium current) in long-QT syndrome (LQT1, LQT2, and LQT3, respectively) are reflected in characteristic QT-interval and T-wave changes; LQT1 prolongs QT without widening the T wave.	Potassium	21-23	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	86-90
11967830-4	2002	Mutants lacking Trk1p, lose high affinity system, but when grown with moderate potassium concentrations, Trk2p seems to replace it.	Potassium	79-88	Trk2p	Saccharomyces cerevisiae S288C	105-110
12058435-7	2002	We especially should pay attention to hypokalemia because of hyperventilation, absorption of potassium with insulin and transudation of potassium from the intestine.	Potassium	93-102	insulin	Homo sapiens	108-115
11967830-1	2002	Potassium uptake in Saccharomyces cerevisiae is mediated by at least two proteins, known as Trk1p and Trk2p.	Potassium	0-9	Trk1p	Saccharomyces cerevisiae S288C	92-97
11967830-7	2002	KlTrkp is a 1070 amino acid peptide that shows, overall, higher homology with Trk2p than with Trk1p, and its disruption gives rise to cells with deficient potassium transport and with an increased K(+) requirement for normal growth.	Potassium	155-164	Trk2p	Saccharomyces cerevisiae S288C	78-83
11967830-1	2002	Potassium uptake in Saccharomyces cerevisiae is mediated by at least two proteins, known as Trk1p and Trk2p.	Potassium	0-9	Trk2p	Saccharomyces cerevisiae S288C	102-107
11967830-3	2002	S. cerevisiae cells also show low affinity potassium uptake, perhaps mediated by Trk2p.	Potassium	43-52	Trk2p	Saccharomyces cerevisiae S288C	81-86
11967830-7	2002	KlTrkp is a 1070 amino acid peptide that shows, overall, higher homology with Trk2p than with Trk1p, and its disruption gives rise to cells with deficient potassium transport and with an increased K(+) requirement for normal growth.	Potassium	155-164	Trk1p	Saccharomyces cerevisiae S288C	94-99
11959953-3	2002	The nanowires are oriented to specific directions, corresponding to the directions of the potassium-ion array on the mica surface having sixfold symmetry.	Potassium	90-99	MHC class I polypeptide-related sequence A	Homo sapiens	117-121
21179792-6	2002	Changes of brain water contents, sodium and potassium contents were relieved by lateral ventricular injection of PACAP in the concentration of 1 x 10(-9), 1 x 10(-10) or 1 x 10(-11) mol respectively before ischemia.	Potassium	44-53	adenylate cyclase activating polypeptide 1	Rattus norvegicus	113-118
11856731-5	2002	In contrast to the B. stearothermophilus enzyme, catalysis of the tyrosine activation step is potassium-dependent in the human tyrosyl-tRNA synthetase.	Potassium	94-103	tyrosyl-tRNA synthetase 1	Homo sapiens	127-150
11856731-6	2002	Specifically, potassium increases the forward rate constant for tyrosine activation 260-fold in the human tyrosyl-tRNA synthetase.	Potassium	14-23	tyrosyl-tRNA synthetase 1	Homo sapiens	106-129
11894131-6	2002	In addition, CH-11-induced activation of caspase-8-like protease in AIDS-KS cells was much less pronounced compared with that in Hut 78; however, a caspase-8 inhibitor, zIETD-fmk, completely blocked the apoptosis.	Potassium	73-75	caspase 8	Homo sapiens	41-50
11950628-1	2002	Adenosine A(1) receptor antagonists have been used effectively as potassium-sparing and renal-function-protective diuretics in new studies.	Potassium	66-75	adenosine A1 receptor	Homo sapiens	0-23
11809752-2	2002	We show that although expression of IRK1 in HEK 293 cells leads to the appearance of a potassium current with strong inward rectifying properties, coexpression of the constitutively active form of Ras (Ras-L61) results in a significant reduction of the mean current density without altering the biophysical properties of the channel.	Potassium	87-96	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	36-40
11934810-0	2002	Neuropeptide Y increases 4-aminopyridine-sensitive transient outward potassium current in rat ventricular myocytes.	Potassium	69-78	neuropeptide Y	Rattus norvegicus	0-14
11934810-2	2002	The modulation of 4-aminopyridine sensitive transient outward potassium current (4-AP I(to)) by neuropeptide Y (NPY) (100 nM) in rat ventricular myocytes was examined using the whole cell voltage-clamp technique.	Potassium	62-71	neuropeptide Y	Rattus norvegicus	96-110
11934810-2	2002	The modulation of 4-aminopyridine sensitive transient outward potassium current (4-AP I(to)) by neuropeptide Y (NPY) (100 nM) in rat ventricular myocytes was examined using the whole cell voltage-clamp technique.	Potassium	62-71	neuropeptide Y	Rattus norvegicus	112-115
11894131-7	2002	Further, a caspase-9 inhibitor, zLEHD-fmk, markedly inhibited Fas-mediated apoptosis in AIDS-KS cells.	Potassium	93-95	caspase 9	Homo sapiens	11-20
11894131-10	2002	In AIDS-KS cells, CH-11 triggered cytochrome c release, an event which was inhibited by zIETD-fmk.	Potassium	8-10	cytochrome c, somatic	Homo sapiens	34-46
11931745-3	2002	Brief kainate exposure caused long-lasting inhibition of a postspike potassium current (I(sAHP)) in CA1 pyramidal cells.	Potassium	69-78	carbonic anhydrase 1	Homo sapiens	100-103
11919278-7	2002	The average pairwise ratio between nonsynonymous substitutions per nucleotide (Ka) and synonymous substitutions per nucleotide (Ks) among vertebrate PGI sequences equals 0.047 +/- 0.019.	Potassium	128-130	glucose-6-phosphate isomerase a	Danio rerio	149-152
11975043-2	2002	The patients with preexisting renal insufficiency could have slowly elevated serum potassium level treated by angiotensin converting enzyme inhibitor.	Potassium	83-92	angiotensin I converting enzyme	Homo sapiens	110-139
11975043-6	2002	CONCLUSIONS: The authors call the attention of danger of high dose angiotensin converting enzyme inhibitor in patients with preexisting renal insufficiency and concomittant drugs elevating serum potassium level.	Potassium	195-204	angiotensin I converting enzyme	Homo sapiens	67-96
11852186-5	2002	314 (2001) 151) reported that the synthesis of the intermediate filament protein nestin was upregulated by potassium-induced depolarization in the rat cortex.	Potassium	107-116	nestin	Rattus norvegicus	81-87
11852186-6	2002	In this letter, we provide supplementary evidence that repeated cortical spreading depression elicited by potassium induces a delayed upregulation of nestin.	Potassium	106-115	nestin	Rattus norvegicus	150-156
11852186-7	2002	However, we argue against the authors" conclusion, "Nestin expression was N-methyl-D-aspartate (NMDA)-receptor dependent since dizocilpine (MK-801) treatment abolished the response" because spreading depression itself is very sensitive to NMDA-receptor block, and the drug treatment was initiated prior to potassium application to the cortex in Holmin et al.	Potassium	306-315	nestin	Rattus norvegicus	52-58
11872658-1	2002	Recent studies have demonstrated that p44/42(MAPK) extracellular signal-regulated kinase (ERK)1 and -2-dependent Na(+)-K(+)-2Cl(-) co-transporter (NKCC) activity may contribute to total potassium uptake by skeletal muscle.	Potassium	186-195	mitogen activated protein kinase 3	Rattus norvegicus	38-41
11834486-0	2002	Potassium (BK(Ca)) currents are reduced in microvascular smooth muscle cells from insulin-resistant rats.	Potassium	0-9	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	11-17
11872658-1	2002	Recent studies have demonstrated that p44/42(MAPK) extracellular signal-regulated kinase (ERK)1 and -2-dependent Na(+)-K(+)-2Cl(-) co-transporter (NKCC) activity may contribute to total potassium uptake by skeletal muscle.	Potassium	186-195	mitogen activated protein kinase 3	Rattus norvegicus	51-102
11948238-3	2002	Here, using differential display RT-PCR, we identify Id2 as an induced gene during serum and potassium deprivation-induced apoptosis of cerebellar granule neurons.	Potassium	93-102	inhibitor of DNA binding 2	Mus musculus	53-56
11959039-3	2002	The situation is complicated by the use of diuretics, ACE inhibitors and spironolactone, all of which may affect renal function and potassium balance.	Potassium	132-141	angiotensin I converting enzyme	Homo sapiens	54-57
11948238-5	2002	Further, gene transfer- mediated overexpression of Id2 induces neuronal cell death both in high potassium and low potassium conditions.	Potassium	96-105	inhibitor of DNA binding 2	Mus musculus	51-54
11948238-5	2002	Further, gene transfer- mediated overexpression of Id2 induces neuronal cell death both in high potassium and low potassium conditions.	Potassium	114-123	inhibitor of DNA binding 2	Mus musculus	51-54
11849756-0	2002	Mitogen-activated protein kinase kinase 7 is activated during low potassium-induced apoptosis in rat cerebellar granule neurons.	Potassium	66-75	mitogen activated protein kinase kinase 7	Rattus norvegicus	0-41
11849449-0	2002	Angiotensin II type 1 receptor blockade ameliorates tubulointerstitial injury induced by chronic potassium deficiency.	Potassium	97-106	angiotensin II receptor, type 1b	Rattus norvegicus	0-30
11953179-14	2002	After HGF transfection, survival rate of hepatocytes poisoned by CCl4 significantly increased (83% vs 61%, P &lt; 0.05), and leakage of intracellular alanine transaminase and potassium ions decreased (35.16 U x L-1 vs 65.31 U x L-1, P &lt; 0.01; and 5.59 mmol/L vs 6.02 mmol/L, P &lt; 0.01 respectively).	Potassium	175-184	hepatocyte growth factor	Homo sapiens	6-9
11851397-3	2002	Hyperrecombination, caused by altered protein kinase C1 (PKC1), is lost in yeast with deletion of yeast InsP(6)K (yInsP(6)K) and can be restored selectively by catalytically active yeast or mammalian InsP(6)Ks.	Potassium	207-209	protein kinase C	Saccharomyces cerevisiae S288C	38-55
11851397-3	2002	Hyperrecombination, caused by altered protein kinase C1 (PKC1), is lost in yeast with deletion of yeast InsP(6)K (yInsP(6)K) and can be restored selectively by catalytically active yeast or mammalian InsP(6)Ks.	Potassium	207-209	protein kinase C	Saccharomyces cerevisiae S288C	57-61
11714706-11	2002	Both pore domains were poorly selective to potassium; however, upon co-expression they partially restored TOK1 channel selectivity.	Potassium	43-52	Tok1p	Saccharomyces cerevisiae S288C	106-110
11849756-2	2002	Using an immune-complex kinase assay, we measured the activation of MKK4 and MKK7 in low potassium (LK)-induced apoptosis of rat cerebellar granule neurons (CGN).	Potassium	89-98	mitogen activated protein kinase kinase 4	Rattus norvegicus	68-72
11849756-2	2002	Using an immune-complex kinase assay, we measured the activation of MKK4 and MKK7 in low potassium (LK)-induced apoptosis of rat cerebellar granule neurons (CGN).	Potassium	89-98	mitogen activated protein kinase kinase 7	Rattus norvegicus	77-81
11804849-1	2002	Contribution of K(+) channels derived from the expression of ERG, KCNQ, and KCNE subtypes, which are responsible for rapidly and slowly activating delayed rectifier K(+) currents (I(Kr) and I(Ks), respectively) in cardiac myocytes, to membrane currents was examined in stomach circular smooth muscle cells (SMCs).	Potassium	192-194	ETS transcription factor ERG	Rattus norvegicus	61-64
11804849-5	2002	It is strongly suggested that I(Kr)- and I(Ks)-like currents functionally identified in rat stomach SMCs are attributable to the expression of ERG1/KCNE2 and KCNQ1/KCNE1, respectively.	Potassium	43-45	potassium voltage-gated channel subfamily H member 2	Rattus norvegicus	143-147
11804849-5	2002	It is strongly suggested that I(Kr)- and I(Ks)-like currents functionally identified in rat stomach SMCs are attributable to the expression of ERG1/KCNE2 and KCNQ1/KCNE1, respectively.	Potassium	43-45	potassium voltage-gated channel subfamily E regulatory subunit 2	Rattus norvegicus	148-153
11804849-5	2002	It is strongly suggested that I(Kr)- and I(Ks)-like currents functionally identified in rat stomach SMCs are attributable to the expression of ERG1/KCNE2 and KCNQ1/KCNE1, respectively.	Potassium	43-45	potassium voltage-gated channel subfamily Q member 1	Rattus norvegicus	158-163
11804849-5	2002	It is strongly suggested that I(Kr)- and I(Ks)-like currents functionally identified in rat stomach SMCs are attributable to the expression of ERG1/KCNE2 and KCNQ1/KCNE1, respectively.	Potassium	43-45	potassium voltage-gated channel subfamily E regulatory subunit 1	Rattus norvegicus	164-169
12064871-1	2002	The effects of platelet-activating factor (PAF) and lyso-platelet-activating factor (L-PAF) at concentrations of 0.25-20 microg/ml on potassium transport and growth of gram-positive and gram-negative bacteria have been investigated in vitro and compared with those of lysophosphatidylcholine (LPC).	Potassium	134-143	PCNA clamp associated factor	Homo sapiens	57-83
11865655-2	2002	Connexin 26 is thought to have an essential role in the transport of potassium ions back to the endolymph of the inner ear after sound stimulation.	Potassium	69-78	gap junction protein beta 2	Homo sapiens	0-11
12064871-1	2002	The effects of platelet-activating factor (PAF) and lyso-platelet-activating factor (L-PAF) at concentrations of 0.25-20 microg/ml on potassium transport and growth of gram-positive and gram-negative bacteria have been investigated in vitro and compared with those of lysophosphatidylcholine (LPC).	Potassium	134-143	PCNA clamp associated factor	Homo sapiens	87-90
11779561-6	2002	Now, demonstration of multiple parallel effects produced by various agonists and antagonists on both NSC1 currents and growth (of trk1 Delta trk2 Delta strains), has identified this non-selective cation pathway as the primary low-affinity uptake route for potassium ions in yeast.	Potassium	256-265	Trk1p	Saccharomyces cerevisiae S288C	130-134
11804618-0	2002	Inhibition of the potassium current IK(SO), in cerebellar granule cells, by the inhibitors of MEK1 activation, PD 98059 and U 0126.	Potassium	18-27	mitogen-activated protein kinase kinase 1	Homo sapiens	94-98
11826096-0	2002	Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.	Potassium	102-111	guanine nucleotide binding protein, alpha q polypeptide	Mus musculus	26-35
11826096-0	2002	Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.	Potassium	102-111	guanine nucleotide binding protein, alpha 11	Mus musculus	40-50
11826122-8	2002	Dantrolene inhibits the high potassium-induced release of NT-3, indicating that release of calcium from intracellular stores is required.	Potassium	29-38	neurotrophin 3	Gallus gallus	58-62
12047800-2	2002	This investigation was undertaken to determine which of the two structural units reconstituting the I(Ks) channel, KCNQ1 (KvLQT1) and KCNE1 (minK/IsK), plays a key role in the cell swelling-induced I(Ks) enhancement and to dissect a possible involvement of tyrosine phosphorylation therein.	Potassium	102-104	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	115-120
12047800-2	2002	This investigation was undertaken to determine which of the two structural units reconstituting the I(Ks) channel, KCNQ1 (KvLQT1) and KCNE1 (minK/IsK), plays a key role in the cell swelling-induced I(Ks) enhancement and to dissect a possible involvement of tyrosine phosphorylation therein.	Potassium	102-104	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	134-139
12047800-8	2002	Taken together, it is very likely that KCNQ1 might primarily participate in the I(Ks) enhancement by osmotic cell swelling.	Potassium	82-84	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	39-44
16120290-0	2002	Bcl-2 sensitive mitochondrial potassium accumulation and swelling in apoptosis.	Potassium	30-39	BCL2 apoptosis regulator	Homo sapiens	0-5
16120290-1	2002	During etoposide-induced apoptosis in HL-60 cells, cytochrome c release was associated with mitochondrial swelling caused by increased mitochondrial potassium uptake.	Potassium	149-158	cytochrome c, somatic	Homo sapiens	51-63
16120290-3	2002	Potassium uptake and swelling of mitochondria were blocked by bcl-2 overexpression.	Potassium	0-9	BCL2 apoptosis regulator	Homo sapiens	62-67
16120290-6	2002	This study suggests several novel aspects of apoptotic signaling: (1) potassium related swelling of mitochondria; (2) inhibition of mitochondrial potassium uptake by bcl-2; (3) co-existence within one system of multiple mechanisms of cytochrome c release: mitochondrial swelling and swelling-independent permeabilization of the outer mitochondrial membrane.	Potassium	146-155	BCL2 apoptosis regulator	Homo sapiens	166-171
16120290-6	2002	This study suggests several novel aspects of apoptotic signaling: (1) potassium related swelling of mitochondria; (2) inhibition of mitochondrial potassium uptake by bcl-2; (3) co-existence within one system of multiple mechanisms of cytochrome c release: mitochondrial swelling and swelling-independent permeabilization of the outer mitochondrial membrane.	Potassium	146-155	cytochrome c, somatic	Homo sapiens	234-246
11846438-8	2002	In contrast, a high concentration of potassium and LPS could induce an acute release of CGRP from DRG neurons, but not from lymphocytes.	Potassium	37-46	calcitonin-related polypeptide alpha	Rattus norvegicus	88-92
11860280-6	2002	High potassium was found to diminish the expression of p53.	Potassium	5-14	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	55-58
11799244-3	2002	We show that betaAR modulation of I(KS) requires targeting of adenosine 3",5"-monophosphate (cAMP)-dependent protein kinase (PKA) and protein phosphatase 1 (PP1) to hKCNQ1 through the targeting protein yotiao.	Potassium	36-38	neuropeptide Y receptor Y4	Homo sapiens	134-155
11799244-3	2002	We show that betaAR modulation of I(KS) requires targeting of adenosine 3",5"-monophosphate (cAMP)-dependent protein kinase (PKA) and protein phosphatase 1 (PP1) to hKCNQ1 through the targeting protein yotiao.	Potassium	36-38	neuropeptide Y receptor Y4	Homo sapiens	157-160
11799244-3	2002	We show that betaAR modulation of I(KS) requires targeting of adenosine 3",5"-monophosphate (cAMP)-dependent protein kinase (PKA) and protein phosphatase 1 (PP1) to hKCNQ1 through the targeting protein yotiao.	Potassium	36-38	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	165-171
11799244-3	2002	We show that betaAR modulation of I(KS) requires targeting of adenosine 3",5"-monophosphate (cAMP)-dependent protein kinase (PKA) and protein phosphatase 1 (PP1) to hKCNQ1 through the targeting protein yotiao.	Potassium	36-38	A-kinase anchoring protein 9	Homo sapiens	194-208
11754478-6	2002	We propose that Nha1p regulates the potassium content of the cell and, as a consequence, can affect the activity of the main K(+) influx system (Trk1p).	Potassium	36-45	Nha1p	Saccharomyces cerevisiae S288C	16-21
11782970-8	2002	Furthermore, levels of TNF significantly increased in the supernatants of both neuron cultures after potassium-induced depolarization.	Potassium	101-110	tumor necrosis factor	Homo sapiens	23-26
11782970-11	2002	Potassium-induced depolarization resulted in the release of TNF in hippocampal neuron cultures within 15 min but not until 24 hr in SH-SY5Y cultures demonstrating a temporally mediated event dependent upon cell type.	Potassium	0-9	tumor necrosis factor	Homo sapiens	60-63
11754478-6	2002	We propose that Nha1p regulates the potassium content of the cell and, as a consequence, can affect the activity of the main K(+) influx system (Trk1p).	Potassium	36-45	Trk1p	Saccharomyces cerevisiae S288C	145-150
12165944-4	2002	During both protocols an insulin-related inhibition of muscle protein degradation occurred; however peritoneal dialysis caused a 20% decrease in forearm phenylalanine rate of disposal (an index of muscle protein synthesis), which correlated with the decline of arterial BCAA and potassium, which were removed via the peritoneal fluid.	Potassium	279-288	insulin	Homo sapiens	25-32
12421609-10	2002	Treatment of recovered slices with high potassium for 90 s causes the re-appearance of CaMKII clusters in nearly all CA1 pyramidal cells examined.	Potassium	40-49	carbonic anhydrase 1	Rattus norvegicus	117-120
11872361-3	2002	Decrease of serum potassium during insulin sensitivity test and intraplatelet free Ca2+ concentration is positively and negatively correlated with insulin sensitivity, respectively.	Potassium	18-27	insulin	Homo sapiens	35-42
11872361-3	2002	Decrease of serum potassium during insulin sensitivity test and intraplatelet free Ca2+ concentration is positively and negatively correlated with insulin sensitivity, respectively.	Potassium	18-27	insulin	Homo sapiens	147-154
11862331-3	2002	In oocytes using the two electrode voltage clamp technique potassium currents of hminK-, HERG- and Kir2.2-expressing oocytes were inhibited by pentobarbital with IC50 values of 0.20, 1.58 and 0.54 mM, respectively.	Potassium	59-68	potassium voltage-gated channel subfamily H member 2	Homo sapiens	89-93
11810210-3	2002	In this study, we investigated the effect of somatostatin (SS), a well-known inhibitory hormone of pancreatic fluid secretion, on I(Ks) in RPAs.	Potassium	132-134	somatostatin	Rattus norvegicus	45-57
12903137-1	2002	Potassium Sensing Oligonucleotide, PSO, showing a high selectivity for K+ was synthesized by connecting 6-FAM and 6-TAMRA at the 5"- and 3"-termini of d(GGG TTA GGG TTA GGG TTA GGG), respectively.	Potassium	0-9	pipecolic acid and sarcosine oxidase	Homo sapiens	35-38
11746438-4	2001	Here we show that in cerebellar granule cells (CGC) the induction of apoptosis, by potassium withdrawal (5 mM KCl), decreases the amount of nuclear NF-kappaB.	Potassium	83-92	nuclear factor kappa B subunit 1	Homo sapiens	148-157
12136480-6	2002	RESULTS: Acute response to ACE inhibitors was the following: SCF fell by 18.4% on the average by the end on therapy week 1; by the end of week 3 renal hemodynamics showed stability, SCF returned to normal, effective renal plasm flow rose by 16.9%, serum potassium rose significantly after 7 days of treatment but did not reach 6 mmol/l.	Potassium	254-263	angiotensin I converting enzyme	Homo sapiens	27-30
11730978-1	2001	The aim of this study was to examine possible modulatory effects of some trophic molecules, i.e. nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and basic fibroblast growth factor (bFGF), on potassium (K(+))-, bradykinin (BK)- or capsaicin (CAPS)-evoked release of glutamate (GLU) from dorsal root ganglion (DRG) neurons in vitro.	Potassium	211-220	fibroblast growth factor 2	Homo sapiens	169-199
12511181-19	2002	It may thus be concluded that: a) generation of the same external mechanical power output during cycling at a pedalling rate of 120 rev.min(-1) causes significantly higher [K+]v changes than when cycling at 60 rev.min(-1), b) the increase of venous plasma potassium concentration during dynamic incremental exercise is linearly related to the metabolic cost of work expressed by the percentage of VO2max (increase as reported previously by Vollestad et al.	Potassium	256-265	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
11739240-9	2001	At high extracellular potassium concentrations the inhibition of KCNQ1 by 3R,4S-293B and 3S,4R-293B was unaffected.	Potassium	22-31	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	65-70
11739587-4	2001	TRbeta is required for hearing because TRbeta-deficient (Thrb(tm1/tm1)) mice have a defective auditory-evoked brainstem response and retarded expression of a potassium current (I(K,f)) in the cochlear inner hair cells.	Potassium	158-167	thyroid hormone receptor beta	Mus musculus	0-6
11739587-4	2001	TRbeta is required for hearing because TRbeta-deficient (Thrb(tm1/tm1)) mice have a defective auditory-evoked brainstem response and retarded expression of a potassium current (I(K,f)) in the cochlear inner hair cells.	Potassium	158-167	thyroid hormone receptor beta	Mus musculus	57-61
11793017-11	2001	Adhering leukocytes to venules decreased by 56 and 86 % while platelets adhering to microvessels was reduced by 52 and 72 % at reperfusion in glucose-insulin-potassium groups with and without dipyridamole, respectively.	Potassium	158-167	insulin	Homo sapiens	150-157
11793017-2	2001	We hypothesized that insulin response to glucose-insulin-potassium infusion might lead to vasodilation in ischemia/reperfusion (I/R).	Potassium	57-66	insulin	Homo sapiens	21-28
11709425-6	2001	Whereas in most COS-7 cells the SAP97-Kv1.5 complexes were retained in the ER, functional analyses in Xenopus oocytes showed that Kv1.5-encoded outward potassium currents were augmented by coexpression with SAP97.	Potassium	152-161	potassium voltage-gated channel subfamily A member 4 L homeolog	Xenopus laevis	38-43
11709425-6	2001	Whereas in most COS-7 cells the SAP97-Kv1.5 complexes were retained in the ER, functional analyses in Xenopus oocytes showed that Kv1.5-encoded outward potassium currents were augmented by coexpression with SAP97.	Potassium	152-161	potassium voltage-gated channel subfamily A member 4 L homeolog	Xenopus laevis	130-135
11734858-6	2001	Here we show that barttin acts as an essential beta-subunit for ClC-Ka and ClC-Kb chloride channels, with which it colocalizes in basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear.	Potassium	176-185	barttin CLCNK type accessory subunit beta	Homo sapiens	18-25
11729223-1	2001	The H(+)/K(+)-ATPase alpha2 subunit (HK alpha 2) of distal colon and renal collecting ducts plays a critical role in potassium and acid-base homeostasis.	Potassium	117-126	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	Mus musculus	37-47
11728473-5	2001	Upon oligochitin-elicitor treatment of root hairs, transient changes in K(+) fluxes and membrane polarization were recorded in wild-type plants, while akt1-1 root hairs showed a reduced amplitude and pronounced delay in the potassium re-uptake process.	Potassium	224-233	K+ transporter 1	Arabidopsis thaliana	151-155
11728473-8	2001	Based on the expression profile and the electrical properties of the root hair plasma membrane we conclude that AKT1-, ATKC- and GORK-mediated potassium transport is essential for osmoregulation and repolarization of the membrane potential in response to elicitors.	Potassium	143-152	K+ transporter 1	Arabidopsis thaliana	112-116
11728473-8	2001	Based on the expression profile and the electrical properties of the root hair plasma membrane we conclude that AKT1-, ATKC- and GORK-mediated potassium transport is essential for osmoregulation and repolarization of the membrane potential in response to elicitors.	Potassium	143-152	gated outwardly-rectifying K+ channel	Arabidopsis thaliana	129-133
11793017-2	2001	We hypothesized that insulin response to glucose-insulin-potassium infusion might lead to vasodilation in ischemia/reperfusion (I/R).	Potassium	57-66	insulin	Homo sapiens	49-56
11741837-9	2001	Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.	Potassium	114-123	gap junction protein, alpha 1	Mus musculus	0-4
11734858-9	2001	This work describes the first known beta-subunit for CLC chloride channels and reveals that heteromers formed by ClC-K and barttin are crucial for renal salt reabsorption and potassium recycling in the inner ear.	Potassium	175-184	barttin CLCNK type accessory subunit beta	Homo sapiens	123-130
11910982-9	2001	Glucose--insulin--potassium infusion in acute myocardial infarction leads to a significant reduction in the mortality relative risk in diabetic patients (ECLA and DIGAMI studies).	Potassium	18-27	insulin	Homo sapiens	9-16
11719447-6	2001	Treatment of KS-Imm cells with NAC in vitro resulted in a dose-dependent inhibition of chemotaxis and invasion through inhibition of gelatinase-A (matrix metalloproteinase-2, MMP-2) activity without altering MMP-2 or MMP-9 mRNA levels.	Potassium	13-15	X-linked Kx blood group	Homo sapiens	31-34
11719447-6	2001	Treatment of KS-Imm cells with NAC in vitro resulted in a dose-dependent inhibition of chemotaxis and invasion through inhibition of gelatinase-A (matrix metalloproteinase-2, MMP-2) activity without altering MMP-2 or MMP-9 mRNA levels.	Potassium	13-15	matrix metallopeptidase 2	Homo sapiens	147-173
11719447-6	2001	Treatment of KS-Imm cells with NAC in vitro resulted in a dose-dependent inhibition of chemotaxis and invasion through inhibition of gelatinase-A (matrix metalloproteinase-2, MMP-2) activity without altering MMP-2 or MMP-9 mRNA levels.	Potassium	13-15	matrix metallopeptidase 2	Homo sapiens	175-180
11719447-6	2001	Treatment of KS-Imm cells with NAC in vitro resulted in a dose-dependent inhibition of chemotaxis and invasion through inhibition of gelatinase-A (matrix metalloproteinase-2, MMP-2) activity without altering MMP-2 or MMP-9 mRNA levels.	Potassium	13-15	matrix metallopeptidase 2	Homo sapiens	208-213
11719447-6	2001	Treatment of KS-Imm cells with NAC in vitro resulted in a dose-dependent inhibition of chemotaxis and invasion through inhibition of gelatinase-A (matrix metalloproteinase-2, MMP-2) activity without altering MMP-2 or MMP-9 mRNA levels.	Potassium	13-15	matrix metallopeptidase 9	Homo sapiens	217-222
11711576-12	2001	In contrast, ghrelin (10(-9)-10(-7) M) dose-dependently inhibited amylase release from pancreatic lobules exposed to 75 mM potassium.	Potassium	123-132	ghrelin and obestatin prepropeptide	Rattus norvegicus	13-20
11514577-2	2001	In Xenopus laevis oocytes, coexpression of hPBP with human mu opioid receptor, human delta opioid receptor, or human somatostatin receptor 2 evoked an agonist-induced increase in potassium conductance of G protein-activated inwardly rectifying potassium channels.	Potassium	179-188	phosphatidylethanolamine binding protein 1	Homo sapiens	43-47
11868861-7	2001	Whereas, intravenous infusion of insulin-dextrose decreased plasma potassium from 6.59 +/- 0.31 mEq/L to 5.76 +/- 0.32 mEq/L (p &lt; 0.001 Vs basal) and 5.84 +/- 0.21 mEq/L (p &lt; 0.001 Vs basal).	Potassium	67-76	insulin	Homo sapiens	33-40
11698549-2	2001	Spontaneous interictal activity was induced in CA1 and CA3 by perfusing hippocampal slices with high potassium, cesium, 4-aminopyridine, or tetraethylammonium chloride, in normal levels of calcium.	Potassium	101-110	carbonic anhydrase 1	Homo sapiens	47-50
11698549-2	2001	Spontaneous interictal activity was induced in CA1 and CA3 by perfusing hippocampal slices with high potassium, cesium, 4-aminopyridine, or tetraethylammonium chloride, in normal levels of calcium.	Potassium	101-110	carbonic anhydrase 3	Homo sapiens	55-58
11703597-0	2001	Effect of potassium depletion on proximal tubule AT1 receptor localization in normal and remnant rat kidney.	Potassium	10-19	angiotensin II receptor, type 1a	Rattus norvegicus	49-52
11703597-1	2001	BACKGROUND: Since both potassium depletion and renal ablation result in proximal tubule hypertrophy and the angiotensin II type 1 (AT1) receptor has been localized in rat proximal tubules, we explored the possibility that the AT1 receptor intracellular distribution is modulated by potassium depletion in proximal tubular cells of 5/6 nephrectomized (Nx) rats.	Potassium	282-291	angiotensin II receptor, type 1a	Rattus norvegicus	131-134
11703597-5	2001	Furthermore, to our knowledge for the first time, the results showed that in potassium depletion, with and without superimposed 5/6 Nx, the AT1 receptor density in proximal tubular cells was dramatically enhanced in the apical membrane, the basal membrane, and in nuclei.	Potassium	77-86	angiotensin II receptor, type 1a	Rattus norvegicus	140-143
11777323-0	2001	Insulin and mineralocorticoids influence on extrarenal potassium metabolism in chronic hemodialysis patients.	Potassium	55-64	insulin	Homo sapiens	0-7
11514577-2	2001	In Xenopus laevis oocytes, coexpression of hPBP with human mu opioid receptor, human delta opioid receptor, or human somatostatin receptor 2 evoked an agonist-induced increase in potassium conductance of G protein-activated inwardly rectifying potassium channels.	Potassium	179-188	somatostatin receptor 2	Homo sapiens	117-140
11431480-0	2001	Differential involvement of initiator caspases in apoptotic volume decrease and potassium efflux during Fas- and UV-induced cell death.	Potassium	80-89	caspase 8	Homo sapiens	38-46
11640963-0	2001	Histamine H1 receptor-mediated inhibition of potassium-evoked release of 5-hydroxytryptamine from mouse forebrains.	Potassium	45-54	histamine receptor H1	Mus musculus	0-21
11598382-3	2001	Nystatin perforated patch recording of Ca(2+)-dependent potassium currents was used to monitor GnRH-induced [Ca(2+)](i) changes.	Potassium	56-65	gonadotropin releasing hormone 1	Rattus norvegicus	95-99
11599006-11	2001	BDNF-induced glutamate release was blocked by L-trans-pyrollidine-2,4-dicalboxylic acid (t-PDC), a glutamate transporter inhibitor, whereas neither the 4-aminopyridine (4AP)- nor high potassium (HK(+))-induced release was blocked by t-PDC.	Potassium	184-193	brain derived neurotrophic factor	Homo sapiens	0-4
11703449-7	2001	The sciatic nerve axons responded to heat, potassium and capsaicin stimulation with a Ca++-dependent CGRP release.	Potassium	43-52	calcitonin-related polypeptide alpha	Rattus norvegicus	101-105
11513809-0	2001	Additive stimulatory effect of extracellular calcium and potassium on non-transferrin ferric iron uptake by HeLa and K562 cells.	Potassium	57-66	transferrin	Homo sapiens	74-85
11762790-8	2001	Urinary potassium and citrate excretion increased with potassium citrate (Period 2).	Potassium	8-17	period circadian regulator 2	Homo sapiens	74-82
11762790-11	2001	Plasma potassium was significantly higher during Period 2, but only one patient developed a mild hyperkalemia (5.0 mmol/l).	Potassium	7-16	period circadian regulator 2	Homo sapiens	49-57
11562470-7	2001	Nucleotide binding to BCK is uniquely mediated by both potassium and magnesium.	Potassium	55-64	creatine kinase B	Rattus norvegicus	22-25
11495695-0	2001	K(+)-p-nitrophenylphosphatase inhibition by neurotensin involves high affinity neurotensin receptor: influence of potassium concentration and enzyme phosphorylation.	Potassium	114-123	neurotensin	Homo sapiens	44-55
11496066-1	2001	ROMK potassium channels are present in the thick ascending limbs and cortical collecting ducts of the kidney and are responsible for potassium ion efflux in these segments.	Potassium	5-14	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	0-4
11514282-3	2001	Acetylcholine and potassium, which act directly on smooth muscle cells to increase [Ca(2+)](i), were found to indirectly elevate [Ca(2+)](i) in endothelial cells; in primary cultures of endothelial cells, neither stimulus affected [Ca(2+)](i), yet substance P increased the fluorescence ratio twofold.	Potassium	18-27	tachykinin precursor 1	Homo sapiens	248-259
11517243-10	2001	When these neurons are induced to undergo apoptosis by lowering extracellular potassium, MEF2A and MEF2D are phosphorylated, followed by decreased DNA binding and cleavage by a caspase-sensitive pathway to N-terminal fragments lacking the transactivation domains.	Potassium	78-87	myocyte enhancer factor 2a	Rattus norvegicus	89-94
11494052-0	2001	Calcitonin gene-related peptide (CGRP), acting via CGRP type 1 receptors, inhibits potassium-stimulated aldosterone secretion and enhances basal catecholamine secretion from rat adrenal gland.	Potassium	83-92	calcitonin-related polypeptide alpha	Rattus norvegicus	0-31
11494052-0	2001	Calcitonin gene-related peptide (CGRP), acting via CGRP type 1 receptors, inhibits potassium-stimulated aldosterone secretion and enhances basal catecholamine secretion from rat adrenal gland.	Potassium	83-92	calcitonin-related polypeptide alpha	Rattus norvegicus	33-37
11494052-0	2001	Calcitonin gene-related peptide (CGRP), acting via CGRP type 1 receptors, inhibits potassium-stimulated aldosterone secretion and enhances basal catecholamine secretion from rat adrenal gland.	Potassium	83-92	calcitonin-related polypeptide alpha	Rattus norvegicus	51-55
11680623-8	2001	The coexpression of KCNQ1 and KCNE2 in HEK293 cells yielded potassium currents that were open at resting voltages, suggesting that these heteromeric channels may underlie the apical potassium conductance in acid-secreting parietal cells that is necessary for the recycling of potassium ions during acid secretion via the H+/K+-ATPase.	Potassium	182-191	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	20-25
11680623-4	2001	Together with the previously shown electrophysiological properties of KCNQ1/KCNE3 channels, this strongly suggests that they form the basolateral potassium conductance that is required for transepithelial cAMP-stimulated chloride secretion.	Potassium	146-155	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	70-75
11680623-4	2001	Together with the previously shown electrophysiological properties of KCNQ1/KCNE3 channels, this strongly suggests that they form the basolateral potassium conductance that is required for transepithelial cAMP-stimulated chloride secretion.	Potassium	146-155	potassium voltage-gated channel, Isk-related subfamily, gene 3	Mus musculus	76-81
11535679-8	2001	Our data indicate that the Abeta actions on specific potassium conductances are modulated through a protein tyrosine kinase pathway and that these effects are selective to cholinergic but not GABAergic cells.	Potassium	53-62	amyloid beta precursor protein	Homo sapiens	27-32
11533128-0	2001	Regulation of slowly activating potassium current (I(Ks)) by secretin in rat pancreatic acinar cells.	Potassium	53-55	secretin	Rattus norvegicus	61-69
11533128-13	2001	The vagal stimulation under the physiological concentration of secretin facilitates I(Ks), which provides an additional driving force for Cl(-) secretion.	Potassium	86-88	secretin	Rattus norvegicus	63-71
11680612-3	2001	Voltage-clamp recordings revealed that the calcium current (I(Ca)) and the outward potassium currents of I(A), I(K) I(KCa) types and the inward rectifier potassium current of I(K1) type exhibited a significant gradient of density (pA/pF) along the region.	Potassium	83-92	casein kappa	Homo sapiens	118-121
11680623-8	2001	The coexpression of KCNQ1 and KCNE2 in HEK293 cells yielded potassium currents that were open at resting voltages, suggesting that these heteromeric channels may underlie the apical potassium conductance in acid-secreting parietal cells that is necessary for the recycling of potassium ions during acid secretion via the H+/K+-ATPase.	Potassium	182-191	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	30-35
11680623-8	2001	The coexpression of KCNQ1 and KCNE2 in HEK293 cells yielded potassium currents that were open at resting voltages, suggesting that these heteromeric channels may underlie the apical potassium conductance in acid-secreting parietal cells that is necessary for the recycling of potassium ions during acid secretion via the H+/K+-ATPase.	Potassium	60-69	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	20-25
11680623-8	2001	The coexpression of KCNQ1 and KCNE2 in HEK293 cells yielded potassium currents that were open at resting voltages, suggesting that these heteromeric channels may underlie the apical potassium conductance in acid-secreting parietal cells that is necessary for the recycling of potassium ions during acid secretion via the H+/K+-ATPase.	Potassium	60-69	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	30-35
11487612-5	2001	We found that the Egr inhibitor does not block the ability of a constitutively active c-Jun construct to induce apoptosis in these cells but does suppress activation of c-Jun-mediated transcription induced by lowering extracellular potassium concentration.	Potassium	232-241	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	169-174
11461170-0	2001	Can glucose-insulin-potassium regimen suppress inflammatory bowel disease?	Potassium	20-29	insulin	Homo sapiens	12-19
11382758-8	2001	This indicates that although the determinants for Nha1-mediated regulation of potassium transport and the cell cycle map very closely in the protein, most probably the function of Nha1 on cell cycle is independent of its ability to extrude potassium cations.	Potassium	78-87	Nha1p	Saccharomyces cerevisiae S288C	50-54
11483714-13	2001	In high external potassium (K(+) 17.5 mM), nociceptin reduced the rate of miniature IPSCs in the presence (Ca(2+) 2.4 mM, Mg(2+) 1.2 mM) but not in the absence of external calcium (Ca(2+) 0 mM, Mg(2+) 10 mM, Cd(2+) 10 microM).	Potassium	17-26	prepronociceptin	Rattus norvegicus	43-53
11473634-13	2001	Solute clearances (+175% for sodium and +26% for potassium) were significantly increased in the H-ANP group, mainly as a result of the increased fluid removal in this group.	Potassium	49-58	natriuretic peptide A	Rattus norvegicus	98-101
11454510-10	2001	Screening of MEN 1 manifestations was carried out by determination of serum calcium, phosphate, parathyroid hormone, prolactin, ACTH, cortisol, IGF-I, gastrin, glucose, insulin, glucagon, serum potassium, aldosterone, plasma renin and urinary hydroxyindoleacetic acid.	Potassium	194-203	menin 1	Homo sapiens	13-18
11483714-18	2001	These results indicate that nociceptin acts via the ORL1 receptor to directly inhibit both primary and secondary RVM neurons by activating a potassium conductance and by inhibiting calcium conductances.	Potassium	141-150	prepronociceptin	Rattus norvegicus	28-38
11483714-18	2001	These results indicate that nociceptin acts via the ORL1 receptor to directly inhibit both primary and secondary RVM neurons by activating a potassium conductance and by inhibiting calcium conductances.	Potassium	141-150	opioid related nociceptin receptor 1	Rattus norvegicus	52-56
11458030-5	2001	Applying these insights to the far more common disorder of low renin hypertension may shed new light on the underlying pathophysiology of this common form of human hypertension, and more clearly define the interactions of dietary constituents such as sodium and potassium in the regulation of blood pressure.	Potassium	262-271	renin	Homo sapiens	63-68
11494334-8	2001	Adenylate cyclase activator, forskolin (FSK), significantly increased PSA secretion and gene expression, and potassium, which causes nonspecific depolarization of membranes, augmented gene expression, and secretion of PSA, but did not influence cAMP release.	Potassium	109-118	kallikrein related peptidase 3	Homo sapiens	218-221
11358956-5	2001	Thus, at pH 6.8 with 20 mm potassium half the current passed by P1H channels was blocked (apparently via two sites approximately 10% into the electrical field) whereas channels with an asparagine substitution (P1N) were fully active.	Potassium	27-36	minichromosome maintenance complex component 3	Homo sapiens	64-67
11410112-0	2001	Effects of high-dose glucose-insulin-potassium on myocardial metabolism after coronary surgery in patients with Type II diabetes.	Potassium	37-46	insulin	Homo sapiens	29-36
11438691-1	2001	The voltage-dependent K(+) channel responsible for the slowly activating delayed K(+) current I(Ks) is composed of pore-forming KCNQ1 and regulatory KCNE1 subunits, which are mutated in familial forms of cardiac long QT syndrome.	Potassium	96-98	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	128-133
11438691-1	2001	The voltage-dependent K(+) channel responsible for the slowly activating delayed K(+) current I(Ks) is composed of pore-forming KCNQ1 and regulatory KCNE1 subunits, which are mutated in familial forms of cardiac long QT syndrome.	Potassium	96-98	potassium voltage-gated channel, Isk-related subfamily, member 1	Mus musculus	149-154
11438691-7	2001	These results, which show that KCNE1 and I(Ks) are involved in K(+) homeostasis, might have important implications for patients with I(Ks)-related long QT syndrome, because hypokalemia is a well known risk factor for the occurrence of torsades de pointes ventricular arrhythmia.	Potassium	135-137	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	31-36
11426445-0	2001	Dissipation of potassium and proton gradients        inhibits mitochondrial hyperpolarization and        cytochrome c release during neural apoptosis.	Potassium	15-24	cytochrome c, somatic	Homo sapiens	105-117
11446723-9	2001	Multivariate adjusted hazard ratios from Cox models were 2.6 [95% confidence intervals (CI) 1.5-4.4] for the low potassium group and 1.7 (95% CI 1.0-2.7) for the high potassium group, with the middle group as reference.	Potassium	113-122	cytochrome c oxidase subunit 8A	Homo sapiens	41-44
11432986-3	2001	When cerebellar granule cells were switched to low potassium medium, the activation of caspase 3 was detected within 6 h, suggesting a role of caspase 3 in mediating apoptosis under conditions of low potassium.	Potassium	51-60	caspase 3	Homo sapiens	87-96
11431495-3	2001	When Xenopus oocytes were injected with KT3.2 cRNA, the resting membrane potential was brought close to the potassium equilibrium potential.	Potassium	108-117	potassium channel, two pore domain subfamily K, member 9 L homeolog	Xenopus laevis	40-45
11439349-2	2001	In the cerebellar cortex IGF-IR mRNA is found in granular cells and IGF-I stimulation is mitogenic and protects cells from low-potassium-induced apoptosis.	Potassium	127-136	insulin-like growth factor I receptor	Mus musculus	25-31
11432988-2	2001	The single channel properties of KCNQ2/KCNQ3 channels underlying neuronal voltage-dependent M-type potassium currents were studied in cell-attached patches from transfected Chinese hamster ovary (CHO) cells.	Potassium	99-108	potassium voltage-gated channel subfamily KQT member 2	Cricetulus griseus	33-38
11432988-2	2001	The single channel properties of KCNQ2/KCNQ3 channels underlying neuronal voltage-dependent M-type potassium currents were studied in cell-attached patches from transfected Chinese hamster ovary (CHO) cells.	Potassium	99-108	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	39-44
11432986-3	2001	When cerebellar granule cells were switched to low potassium medium, the activation of caspase 3 was detected within 6 h, suggesting a role of caspase 3 in mediating apoptosis under conditions of low potassium.	Potassium	200-209	caspase 3	Homo sapiens	87-96
11432986-3	2001	When cerebellar granule cells were switched to low potassium medium, the activation of caspase 3 was detected within 6 h, suggesting a role of caspase 3 in mediating apoptosis under conditions of low potassium.	Potassium	200-209	caspase 3	Homo sapiens	143-152
11432986-4	2001	In the same conditions, lithium (5 mM) inhibited the activation of caspase 3 induced by low potassium.	Potassium	92-101	caspase 3	Homo sapiens	67-76
11432986-9	2001	Low potassium induced the dephosphorylation and inactivation of PKB, whereas when lithium was present PKB was not dephosphorylated.	Potassium	4-13	protein tyrosine kinase 2 beta	Homo sapiens	64-67
11439349-2	2001	In the cerebellar cortex IGF-IR mRNA is found in granular cells and IGF-I stimulation is mitogenic and protects cells from low-potassium-induced apoptosis.	Potassium	127-136	insulin-like growth factor 1	Mus musculus	25-30
11294880-0	2001	Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3.	Potassium	43-52	solute carrier family 24 member 3	Homo sapiens	101-106
11439220-6	2001	Plasma potassium (K(+)) was lower in the FDP group (P&lt;0.01).	Potassium	7-16	fructose-bisphosphatase 1	Rattus norvegicus	41-44
11394742-5	2001	A novel clinical test involving an epinephrine challenge in the decedent"s mother implicated a potential defect in the phase 3 potassium current encoded by the gene KVLQT1.	Potassium	127-136	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	165-171
11412807-13	2001	A strong positive correlation was observed between blood pressure (SBP and DBP) and body mass index, total serum cholesterol and sodium to potassium ratio.	Potassium	139-148	selenium binding protein 1	Homo sapiens	67-70
11404400-8	2001	Compared with another transient potassium current formed by Kv1.1/Kvbeta1, Kv4.3/KChIP1 current was much more sensitive to arachidonic acid.	Potassium	32-41	potassium channel, voltage gated shaker related subfamily A, member 1 S homeolog	Xenopus laevis	60-65
11404400-8	2001	Compared with another transient potassium current formed by Kv1.1/Kvbeta1, Kv4.3/KChIP1 current was much more sensitive to arachidonic acid.	Potassium	32-41	potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog	Xenopus laevis	75-80
11404400-8	2001	Compared with another transient potassium current formed by Kv1.1/Kvbeta1, Kv4.3/KChIP1 current was much more sensitive to arachidonic acid.	Potassium	32-41	Kv channel interacting protein 1 L homeolog	Xenopus laevis	81-87
11389833-2	2001	Recently, external K1 toxin was shown to directly activate TOK1 channels in the plasma membranes of sensitive yeast cells, leading to excess potassium flux and cell death.	Potassium	141-150	Tok1p	Saccharomyces cerevisiae S288C	59-63
11569504-3	2001	Adh Ka/Ks values are lower in intrasubgenus comparisons involving species of the Sophophora group than when these species are compared to the D. immigrans and S. lebanonensis, and this difference does not occur in the Adh-dup comparisons.	Potassium	7-9	Alcohol dehydrogenase	Drosophila melanogaster	0-3
11435055-0	2001	Comparison of a continuous glucose-insulin-potassium infusion versus intermittent bolus application of insulin on perioperative glucose control and hormone status in insulin-treated type 2 diabetics.	Potassium	43-52	insulin	Homo sapiens	35-42
11353725-1	2001	Hypokalaemic periodic paralysis (hypoPP) is an autosomal dominant muscle disorder characterized by episodic attacks of muscle weakness associated with a decrease in blood potassium levels.	Potassium	171-180	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	33-39
11414663-0	2001	Modulation of potassium current and calcium influx by somatostatin in rod bipolar cells isolated from the rabbit retina via sst2 receptors.	Potassium	14-23	somatostatin	Oryctolagus cuniculus	54-66
11319556-0	2001	KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel.	Potassium	46-55	potassium two pore domain channel subfamily K member 2	Homo sapiens	0-5
11331359-0	2001	p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis.	Potassium	39-48	mitogen-activated protein kinase 14	Homo sapiens	0-3
11331359-8	2001	Moreover, we found that activation of p38 is required for caspase 3 and 9 cleavage, suggesting that potassium currents enhancement is required for caspase activation.	Potassium	100-109	mitogen-activated protein kinase 14	Homo sapiens	38-41
11382805-4	2001	Similar results were obtained when restricting EAAC1 to Na(+) translocation steps by removing potassium, thus, demonstrating (1) that substrate translocation of EAAC1 is coupled to inward movement of positive charge and, therefore, electrogenic; and (2) the existence of at least two distinct intermediates in the Na(+)-binding and glutamate translocation limb of the EAAC1 transport cycle.	Potassium	94-103	solute carrier family 1 member 1	Homo sapiens	47-52
11382805-4	2001	Similar results were obtained when restricting EAAC1 to Na(+) translocation steps by removing potassium, thus, demonstrating (1) that substrate translocation of EAAC1 is coupled to inward movement of positive charge and, therefore, electrogenic; and (2) the existence of at least two distinct intermediates in the Na(+)-binding and glutamate translocation limb of the EAAC1 transport cycle.	Potassium	94-103	solute carrier family 1 member 1	Homo sapiens	161-166
11382805-4	2001	Similar results were obtained when restricting EAAC1 to Na(+) translocation steps by removing potassium, thus, demonstrating (1) that substrate translocation of EAAC1 is coupled to inward movement of positive charge and, therefore, electrogenic; and (2) the existence of at least two distinct intermediates in the Na(+)-binding and glutamate translocation limb of the EAAC1 transport cycle.	Potassium	94-103	solute carrier family 1 member 1	Homo sapiens	161-166
11402167-1	2001	The SOS3 (for SALT OVERLY SENSITIVE3) calcium binding protein and SOS2 protein kinase are required for sodium and potassium ion homeostasis and salt tolerance in Arabidopsis.	Potassium	114-123	Calcium-binding EF-hand family protein	Arabidopsis thaliana	4-8
11402167-1	2001	The SOS3 (for SALT OVERLY SENSITIVE3) calcium binding protein and SOS2 protein kinase are required for sodium and potassium ion homeostasis and salt tolerance in Arabidopsis.	Potassium	114-123	Calcium-binding EF-hand family protein	Arabidopsis thaliana	14-36
11402167-1	2001	The SOS3 (for SALT OVERLY SENSITIVE3) calcium binding protein and SOS2 protein kinase are required for sodium and potassium ion homeostasis and salt tolerance in Arabidopsis.	Potassium	114-123	Protein kinase superfamily protein	Arabidopsis thaliana	66-70
11331359-8	2001	Moreover, we found that activation of p38 is required for caspase 3 and 9 cleavage, suggesting that potassium currents enhancement is required for caspase activation.	Potassium	100-109	caspase 3	Homo sapiens	58-67
11328912-1	2001	BACKGROUND: The angiotensin II (AT II) type I receptor antagonist losartan has been reported to increase urinary uric acid and potassium excretion.	Potassium	127-136	angiotensinogen	Homo sapiens	16-30
11328912-1	2001	BACKGROUND: The angiotensin II (AT II) type I receptor antagonist losartan has been reported to increase urinary uric acid and potassium excretion.	Potassium	127-136	angiotensinogen	Homo sapiens	32-37
11328912-8	2001	Serum aldosterone and urinary aldosterone excretion were significantly reduced only during ACE inhibitor treatment, which might explain the variable effects on potassium homeostasis.	Potassium	160-169	angiotensin I converting enzyme	Homo sapiens	91-94
11377135-2	2001	Therefore, the glucose-insulin-potassium regimen might be beneficial in acute myocardial infarction and useful in the management of patients with septicemia, septic shock, and other inflammatory diseases in which tumor necrosis factor-alpha and macrophage migration-inhibitory factor have important roles.	Potassium	31-40	insulin	Homo sapiens	23-30
11377135-2	2001	Therefore, the glucose-insulin-potassium regimen might be beneficial in acute myocardial infarction and useful in the management of patients with septicemia, septic shock, and other inflammatory diseases in which tumor necrosis factor-alpha and macrophage migration-inhibitory factor have important roles.	Potassium	31-40	tumor necrosis factor	Homo sapiens	213-240
11377135-2	2001	Therefore, the glucose-insulin-potassium regimen might be beneficial in acute myocardial infarction and useful in the management of patients with septicemia, septic shock, and other inflammatory diseases in which tumor necrosis factor-alpha and macrophage migration-inhibitory factor have important roles.	Potassium	31-40	macrophage migration inhibitory factor	Homo sapiens	245-283
11331054-2	2001	SUBJECTS AND METHODS: We studied 25 patients treated with ACE inhibitors and spironolactone who were admitted to the emergency room with a serum potassium level &gt; 6 mmol/L.	Potassium	145-154	angiotensin I converting enzyme	Homo sapiens	58-61
11320260-8	2001	KCNE1 increased the slow component of the delayed rectifier, I(Ks), without clear phenotypic sequelae.	Potassium	63-65	potassium voltage-gated channel subfamily E member 1	Cavia porcellus	0-5
11320260-9	2001	In contrast, KCNE1-D76N suppressed I(Ks) and markedly slowed repolarization, leading to frequent EADs and electrocardiographic QT prolongation.	Potassium	37-39	potassium voltage-gated channel subfamily E member 1	Cavia porcellus	13-18
11282358-0	2001	Blockade of U50488H on potassium currents of acutely isolated mouse hippocampal CA3 pyramidal neurons.	Potassium	23-32	carbonic anhydrase 3	Mus musculus	80-83
11318774-4	2001	RESULTS: We found the maximum (Cmax) and average (Cav) plasma concentrations of salbutamol to be correlated (P &lt; 0.0001) to change in plasma potassium (Cmax r = 0.904; Cav r = 0.899) and tremor (Cmax r = 0.875; Cav r = 0.857).	Potassium	144-153	caveolin 2	Homo sapiens	50-53
11323770-2	2001	MR-spectroscopy (MRS) records protons from tissue chemicals other than water, intrinsic phosphorus containing metabolites, sodium, potassium, carbon, nitrogen, and fluorine.	Potassium	131-140	sterile alpha motif domain containing 11	Mus musculus	17-20
11318774-4	2001	RESULTS: We found the maximum (Cmax) and average (Cav) plasma concentrations of salbutamol to be correlated (P &lt; 0.0001) to change in plasma potassium (Cmax r = 0.904; Cav r = 0.899) and tremor (Cmax r = 0.875; Cav r = 0.857).	Potassium	144-153	caveolin 2	Homo sapiens	171-174
11318774-4	2001	RESULTS: We found the maximum (Cmax) and average (Cav) plasma concentrations of salbutamol to be correlated (P &lt; 0.0001) to change in plasma potassium (Cmax r = 0.904; Cav r = 0.899) and tremor (Cmax r = 0.875; Cav r = 0.857).	Potassium	144-153	caveolin 2	Homo sapiens	171-174
11548593-17	2001	For example, production relaxing of the factor by an epithelium and endothelium, being calcium-dependent process, is regulated at involvement calmodulin-similar Ca(2+)-connecting proteins and protein kinase C. Control of tone SM through change of membrane potential relaxing factor carries out by paravariation of potassium conduction of a membrane SM, and, is more probable than all through calcium-dependent and ATP-sensitive components.	Potassium	314-323	calmodulin 1	Homo sapiens	142-152
11239718-0	2001	Activation of CB1 cannabinoid receptors in rat hippocampal slices inhibits potassium-evoked cholecystokinin release, a possible mechanism contributing to the spatial memory defects produced by cannabinoids.	Potassium	75-84	cannabinoid receptor 1	Rattus norvegicus	14-17
11239718-0	2001	Activation of CB1 cannabinoid receptors in rat hippocampal slices inhibits potassium-evoked cholecystokinin release, a possible mechanism contributing to the spatial memory defects produced by cannabinoids.	Potassium	75-84	cholecystokinin	Rattus norvegicus	92-107
11239718-4	2001	The CB1 agonist R(+)WIN 55,212-2 (WIN+), at 1 and 10 micromol, strongly inhibited potassium-evoked CCK release from rat hippocampal slices, while the inactive isomer S(-)WIN,55,212-3 (WIN-) had no effect.	Potassium	82-91	cannabinoid receptor 1	Rattus norvegicus	4-7
11239718-4	2001	The CB1 agonist R(+)WIN 55,212-2 (WIN+), at 1 and 10 micromol, strongly inhibited potassium-evoked CCK release from rat hippocampal slices, while the inactive isomer S(-)WIN,55,212-3 (WIN-) had no effect.	Potassium	82-91	cholecystokinin	Rattus norvegicus	99-102
11322560-7	2001	The polymeric units are made up by the monomeric units [Bu8N4K2]2-, in which one potassium is eta1:eta1:eta1:eta5 and the other eta5:eta1:eta5:eta1 bonded inside the porphyrinogen cavity.	Potassium	81-90	secreted phosphoprotein 1	Homo sapiens	94-98
11322560-7	2001	The polymeric units are made up by the monomeric units [Bu8N4K2]2-, in which one potassium is eta1:eta1:eta1:eta5 and the other eta5:eta1:eta5:eta1 bonded inside the porphyrinogen cavity.	Potassium	81-90	secreted phosphoprotein 1	Homo sapiens	99-103
11322560-7	2001	The polymeric units are made up by the monomeric units [Bu8N4K2]2-, in which one potassium is eta1:eta1:eta1:eta5 and the other eta5:eta1:eta5:eta1 bonded inside the porphyrinogen cavity.	Potassium	81-90	secreted phosphoprotein 1	Homo sapiens	99-103
11322560-7	2001	The polymeric units are made up by the monomeric units [Bu8N4K2]2-, in which one potassium is eta1:eta1:eta1:eta5 and the other eta5:eta1:eta5:eta1 bonded inside the porphyrinogen cavity.	Potassium	81-90	secreted phosphoprotein 1	Homo sapiens	99-103
11322560-7	2001	The polymeric units are made up by the monomeric units [Bu8N4K2]2-, in which one potassium is eta1:eta1:eta1:eta5 and the other eta5:eta1:eta5:eta1 bonded inside the porphyrinogen cavity.	Potassium	81-90	secreted phosphoprotein 1	Homo sapiens	99-103
11245689-0	2001	Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent AKT phosphorylation by tumor necrosis factor-(alpha) rescues axotomized retinal ganglion cells from retrograde cell death in vivo.	Potassium	13-22	tumor necrosis factor	Homo sapiens	99-127
11245689-3	2001	In accordance with our previous findings, TNF-alpha decreased outward potassium currents in RGCs.	Potassium	70-79	tumor necrosis factor	Homo sapiens	42-51
11245689-4	2001	Antagonism of the TNF-alpha-induced decrease in outward potassium currents with the potassium channel opener minoxidilsulfate (as verified by electrophysiology) abolished neuroprotection.	Potassium	56-65	tumor necrosis factor	Homo sapiens	18-27
11274080-8	2001	RESULTS: In the presence of ET-1 (0.1 nM or higher concentration), the rate of ouabain-sensitive potassium (86Rb) uptake was diminished.	Potassium	97-106	endothelin 1	Homo sapiens	28-32
11325073-11	2001	4) Body mass index and the ratio of sodium to potassium excretion showed significant and positive associations with SBP and DBP in multiple linear regression analyses.	Potassium	46-55	selenium binding protein 1	Homo sapiens	116-119
11224662-1	2001	In target organs, insulin switches substrate utilization from free fatty acids to glucose, a change that: (i) is oxygen-efficient; (ii) repletes glycogen stores; (iii) removes potentially toxic fatty acids; and (iv) restores intracellular potassium.	Potassium	239-248	insulin	Homo sapiens	18-25
11508824-11	2001	They also strongly suggest that potassium currents in Ranvier nodes of Xenopus are mainly carried by an ensemble of Kv1.1 and 1.2 channels.	Potassium	32-41	potassium channel, voltage gated shaker related subfamily A, member 1 S homeolog	Xenopus laevis	116-127
11325073-11	2001	4) Body mass index and the ratio of sodium to potassium excretion showed significant and positive associations with SBP and DBP in multiple linear regression analyses.	Potassium	46-55	D-box binding PAR bZIP transcription factor	Homo sapiens	124-127
11223191-1	2001	In Ren-2 rats, plasma active renin and prorenin increase following binephrectomy (BNx) related to increasing plasma potassium.	Potassium	116-125	renin	Rattus norvegicus	29-34
11448739-4	2001	Activation and phosphorylation of PEPCase upon illumination were dependent on the presence of potassium in the incubation medium.	Potassium	94-103	phosphoenolpyruvate carboxykinase 1	Homo sapiens	34-41
11226272-2	2001	KCNQ1 associates with a regulatory subunit, KCNE1, to produce the cardiac repolarizing current, I(Ks).	Potassium	98-100	potassium voltage-gated channel, subfamily Q, member 1	Mus musculus	0-5
11226272-2	2001	KCNQ1 associates with a regulatory subunit, KCNE1, to produce the cardiac repolarizing current, I(Ks).	Potassium	98-100	potassium voltage-gated channel, Isk-related subfamily, member 1	Mus musculus	44-49
11159728-11	2001	Increasing extracellular potassium from 5 to 15 mM during angiotensin II stimulation caused a [Ca(2+)](i) decrease (26+/-4%) smaller than BK which was charybdotoxin-insensitive.	Potassium	25-34	angiotensinogen	Rattus norvegicus	58-72
11160379-9	2001	In view of the crucial role of M currents in modulating neuronal excitability, our findings provide important insight into the functional consequences of differential expression of KCNQ2 splice variants: dampened potassium conductances in the developing brain could shape firing repertoires to provide cues for proliferation rather than differentiation.	Potassium	213-222	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	181-186
11222744-2	2001	Potassium-induced depolarization of GT1-7 neurons causes a dose-dependent monotonic increase in [Ca2+]i and elicits a bell-shaped cAMP response.	Potassium	0-9	beta-1,4-galactosyltransferase 1	Homo sapiens	36-39
11083864-0	2001	p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons.	Potassium	51-60	mitogen activated protein kinase 14	Rattus norvegicus	0-3
11042179-5	2001	If potassium depletion was used to interfere with early stages of coated pit formation, both GHR endocytosis and ubiquitination were inhibited.	Potassium	3-12	growth hormone receptor	Homo sapiens	93-96
11162114-11	2001	(vii) Potassium ions are observed to bind preferentially to deep/major groove atoms at RpY steps, essentially d(GpC), r(GpC), and r(ApU), by forming ion-bridges between electronegative atoms of adjacent base-pairs.	Potassium	6-15	glycophorin C (Gerbich blood group)	Homo sapiens	112-115
11162114-11	2001	(vii) Potassium ions are observed to bind preferentially to deep/major groove atoms at RpY steps, essentially d(GpC), r(GpC), and r(ApU), by forming ion-bridges between electronegative atoms of adjacent base-pairs.	Potassium	6-15	glycophorin C (Gerbich blood group)	Homo sapiens	120-123
11269692-10	2001	The results of this study demonstrate that AS, KS, and TS lowered the serum total cholesterol level by enhancing the hepatic LDL receptor mRNA level.	Potassium	47-49	low density lipoprotein receptor	Rattus norvegicus	125-137
11164846-6	2001	RESULTS: Carvedilol at a concentration of 10 microM blocked HERG potassium tail currents by 47%.	Potassium	65-74	potassium voltage-gated channel subfamily H member 2	Homo sapiens	60-64
11207809-5	2001	Potassium depletion which disrupts clathrin-mediated endocytosis, inhibited internalization of NCAM.	Potassium	0-9	neural cell adhesion molecule 1	Homo sapiens	95-99
11181838-6	2001	Gel-shift assays reveal three complexes that bind to the NF-kappaB binding site in high potassium medium.	Potassium	88-97	nuclear factor kappa B subunit 1	Homo sapiens	57-66
11181838-8	2001	Overexpression of p65 by transfection inhibits low potassium-induced apoptosis, whereas overexpression of IkappaBalpha promotes apoptosis even in high potassium medium.	Potassium	51-60	RELA proto-oncogene, NF-kB subunit	Homo sapiens	18-21
11181838-8	2001	Overexpression of p65 by transfection inhibits low potassium-induced apoptosis, whereas overexpression of IkappaBalpha promotes apoptosis even in high potassium medium.	Potassium	151-160	NFKB inhibitor alpha	Homo sapiens	106-118
11181838-12	2001	Phosphorylation of IkappaBbeta is, however, reduced by low potassium treatment.	Potassium	59-68	NFKB inhibitor beta	Homo sapiens	19-30
11201090-3	2001	The potassium-evoked release of CCK-LI at earlier and later time points has, however, not been studied.	Potassium	4-13	cholecystokinin	Homo sapiens	32-35
11170435-9	2001	Surprisingly, the subsequent hsp90-dependent step, which is rate-limiting for receptor activation, is also potassium-dependent.	Potassium	107-116	heat shock protein 90 alpha family class A member 1	Homo sapiens	29-34
11170435-11	2001	Because the priming step requires both sustained high levels of ATP and YDJ-1 for optimal activity and because both steps require potassium, we predict that receptor-bound hsp70 undergoes iterative ratcheting between its ATP- and ADP-dependent conformations in opening the hydrophobic steroid binding pocket.	Potassium	130-139	heat shock protein family A (Hsp70) member 4	Homo sapiens	172-177
11201090-5	2001	During the first week after transection of the sciatic nerve a tendency towards an elevation of the potassium-induced (100 mM in the perfusion fluid) release of spinal CCK-LI was observed.	Potassium	100-109	cholecystokinin	Homo sapiens	168-171
11163793-0	2001	Regulation of a mammalian Shaker-related potassium channel, hKv1.5, by extracellular potassium and pH.	Potassium	41-50	potassium voltage-gated channel subfamily A member 5	Homo sapiens	60-66
11368012-7	2001	Laurate perturbation of the visible absorption spectrum of CYP4A7 allowed for determination of the spectral binding constant (KS) in the absence and presence of cytochrome b5 (13 and 43 microM, respectively).	Potassium	126-128	cytochrome P450 4A7	Oryctolagus cuniculus	59-65
11031272-5	2001	Reverse-Northern and Northern blot analyses confirmed that treatment with low potassium induces overexpression of NP1 mRNA, with a subsequent increase in NP1 protein levels.	Potassium	78-87	neuronal pentraxin 1	Homo sapiens	114-117
11031272-5	2001	Reverse-Northern and Northern blot analyses confirmed that treatment with low potassium induces overexpression of NP1 mRNA, with a subsequent increase in NP1 protein levels.	Potassium	78-87	neuronal pentraxin 1	Homo sapiens	154-157
11031272-6	2001	Time-course studies indicated that overexpression of NP1 protein reaches a maximum after 4 h of exposure to potassium deprivation and 4 h before significant cell death.	Potassium	108-117	neuronal pentraxin 1	Homo sapiens	53-56
11031272-7	2001	Incubation of cerebellar granule cells with an antisense oligodeoxyribonucleotide directed against NP1 mRNA reduced low potassium-evoked NP1 protein levels by 60% and attenuated neuronal death by 50%, whereas incubation with the corresponding sense oligodeoxyribonucleotide was ineffective.	Potassium	120-129	neuronal pentraxin 1	Homo sapiens	99-102
11031272-7	2001	Incubation of cerebellar granule cells with an antisense oligodeoxyribonucleotide directed against NP1 mRNA reduced low potassium-evoked NP1 protein levels by 60% and attenuated neuronal death by 50%, whereas incubation with the corresponding sense oligodeoxyribonucleotide was ineffective.	Potassium	120-129	neuronal pentraxin 1	Homo sapiens	137-140
11146066-0	2001	Inhibition of astrocyte TNFalpha expression by extracellular potassium.	Potassium	61-70	tumor necrosis factor	Homo sapiens	24-32
11133504-2	2001	Inhibition of coated-pit function by potassium depletion severely reduced both SP-A and SP-A-mediated lipid internalization.	Potassium	37-46	surfactant protein A1	Homo sapiens	79-83
11133504-2	2001	Inhibition of coated-pit function by potassium depletion severely reduced both SP-A and SP-A-mediated lipid internalization.	Potassium	37-46	surfactant protein A1	Homo sapiens	88-92
11169627-0	2001	Reduced potassium currents in old rat CA1 hippocampal neurons.	Potassium	8-17	carbonic anhydrase 1	Rattus norvegicus	38-41
11169627-2	2001	We compared potassium currents in CA1 hippocampal neurons dissociated from young (2-3 months old) and old (26-30 months old) Sprague-Dawley rats.	Potassium	12-21	carbonic anhydrase 1	Rattus norvegicus	34-37
11169627-11	2001	This reduction of potassium currents could account for the prolongation of action potentials reported previously for old rat CA1 hippocampal neurons.	Potassium	18-27	carbonic anhydrase 1	Rattus norvegicus	125-128
11146049-5	2001	When 2DIV slices were exposed to combined high potassium (K(+), 10 mM) and forskolin (10 microM) stimulation for 3 h, PPT mRNA levels were increased within areas of the brain normally associated with tachykinin production.	Potassium	47-56	tachykinin, precursor 1	Rattus norvegicus	118-121
11204289-4	2001	The changes in serum potassium and magnesium were both inversely related to the insulin-mediated glucose uptake (r= -0.62, P&lt; 0.0001; r= -0.31, P&lt; 0.05, respectively).	Potassium	21-30	insulin	Homo sapiens	80-87
11544639-3	2001	In this study we have examined the role of p38 kinase in the potassium deprivation model of apoptosis in rat cerebellar granule neurons (CGN).	Potassium	61-70	mitogen activated protein kinase 14	Rattus norvegicus	43-46
11544639-4	2001	An increase in p38 kinase activity was observed with a 15-minute potassium deprivation when compared to the basal level.	Potassium	65-74	mitogen activated protein kinase 14	Rattus norvegicus	15-18
11544639-5	2001	We also found that SB203580 and PD169316, specific p38 kinase inhibitors, significantly attenuated apoptosis in potassium-deprived cells in a dose dependent manner.	Potassium	112-121	mitogen activated protein kinase 14	Rattus norvegicus	51-54
11769308-3	2001	In a network model of area CA3, the time scale for CCH-delta corresponded to the decay constant of the gating variable of the calcium-dependent potassium (K-AHP) current, that of CCH-theta to an intrinsic subthreshold membrane potential oscillation of the pyramidal cells, and that of CCH-gamma to the decay constant of GABAergic inhibitory synaptic potentials onto the pyramidal cells.	Potassium	144-153	carbonic anhydrase 3	Rattus norvegicus	27-30
11149901-0	2001	Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons.	Potassium	91-100	calcium/calmodulin dependent protein kinase IV	Homo sapiens	0-51
11149901-0	2001	Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons.	Potassium	91-100	calcium/calmodulin dependent protein kinase IV	Homo sapiens	53-59
12107341-7	2001	Bcl-2 protein distributed in the tubules of the OM was significantly decreased in potassium-depleted and potassium-repleted rats compared with control rats, while immunoreactivity for Bax protein tended to increase above control levels in potassium-depleted rats.	Potassium	82-91	BCL2, apoptosis regulator	Rattus norvegicus	0-5
11134230-1	2001	I(Ks), a slowly activating delayed rectifier K(+) current through channels formed by the assembly of two subunits KCNQ1 (KvLQT1) and KCNE1 (minK), contributes to the control of the cardiac action potential duration.	Potassium	2-4	potassium voltage-gated channel subfamily KQT member 1	Cricetulus griseus	114-119
11134230-1	2001	I(Ks), a slowly activating delayed rectifier K(+) current through channels formed by the assembly of two subunits KCNQ1 (KvLQT1) and KCNE1 (minK), contributes to the control of the cardiac action potential duration.	Potassium	2-4	potassium voltage-gated channel subfamily E member 1	Cricetulus griseus	133-138
11077079-3	2001	Perfusion of hippocampal slices with 0-added calcium and high potassium induced field bursts in CA1 and the dentate gyrus.	Potassium	62-71	carbonic anhydrase 1	Homo sapiens	96-99
11135170-14	2001	Low-grade ischemic preconditioning and potassium cardioplegia enhanced translocation of protein kinase C alpha to the membrane, whereas high-grade ischemic preconditioning also enhanced translocation of protein kinase C delta and epsilon.	Potassium	39-48	protein kinase C, alpha	Rattus norvegicus	88-110
11135170-16	2001	CONCLUSIONS: These results suggest that myocardial protection by low-grade ischemic preconditioning and potassium cardioplegia are mediated through enhanced translocation of protein kinase C alpha to the membrane.	Potassium	104-113	protein kinase C, alpha	Rattus norvegicus	174-196
11161471-5	2001	In a functional assay, we used the synapsin promoter to evaluate the effect of Bcl-X(L) overexpression on potassium-withdrawal-induced apoptosis of cerebellar granule neurons.	Potassium	106-115	Bcl2-like 1	Rattus norvegicus	79-87
11738132-2	2001	Somatodendritic Kv2.1 channels contribute a major component of delayed rectifier potassium current in cultured hippocampal neurons, where Kv2.1 is localized to large clusters on the soma and proximal dendrites.	Potassium	81-90	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	16-21
11738132-2	2001	Somatodendritic Kv2.1 channels contribute a major component of delayed rectifier potassium current in cultured hippocampal neurons, where Kv2.1 is localized to large clusters on the soma and proximal dendrites.	Potassium	81-90	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	138-143
11738132-7	2001	Confocal imaging showed a preferential association of Kv2.1 with the basal membrane in cultured neurons, and electrophysiological recordings from neurons cultured on transistors revealed that Kv2.1 contributed the bulk of a previously described adherens junction delayed rectifier potassium conductance.	Potassium	281-290	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	192-197
12107341-7	2001	Bcl-2 protein distributed in the tubules of the OM was significantly decreased in potassium-depleted and potassium-repleted rats compared with control rats, while immunoreactivity for Bax protein tended to increase above control levels in potassium-depleted rats.	Potassium	105-114	BCL2, apoptosis regulator	Rattus norvegicus	0-5
12107341-7	2001	Bcl-2 protein distributed in the tubules of the OM was significantly decreased in potassium-depleted and potassium-repleted rats compared with control rats, while immunoreactivity for Bax protein tended to increase above control levels in potassium-depleted rats.	Potassium	105-114	BCL2, apoptosis regulator	Rattus norvegicus	0-5
12107341-8	2001	RT-PCR for bcl-2 and bax demonstrated a significant decrease in levels of bcl-2 mRNA in potassium-depleted and potassium-repleted rats relative to those in controls.	Potassium	88-97	BCL2, apoptosis regulator	Rattus norvegicus	11-16
12107341-8	2001	RT-PCR for bcl-2 and bax demonstrated a significant decrease in levels of bcl-2 mRNA in potassium-depleted and potassium-repleted rats relative to those in controls.	Potassium	88-97	BCL2 associated X, apoptosis regulator	Rattus norvegicus	21-24
12107341-8	2001	RT-PCR for bcl-2 and bax demonstrated a significant decrease in levels of bcl-2 mRNA in potassium-depleted and potassium-repleted rats relative to those in controls.	Potassium	88-97	BCL2, apoptosis regulator	Rattus norvegicus	74-79
12107341-8	2001	RT-PCR for bcl-2 and bax demonstrated a significant decrease in levels of bcl-2 mRNA in potassium-depleted and potassium-repleted rats relative to those in controls.	Potassium	111-120	BCL2, apoptosis regulator	Rattus norvegicus	11-16
12107341-8	2001	RT-PCR for bcl-2 and bax demonstrated a significant decrease in levels of bcl-2 mRNA in potassium-depleted and potassium-repleted rats relative to those in controls.	Potassium	111-120	BCL2 associated X, apoptosis regulator	Rattus norvegicus	21-24
12107341-8	2001	RT-PCR for bcl-2 and bax demonstrated a significant decrease in levels of bcl-2 mRNA in potassium-depleted and potassium-repleted rats relative to those in controls.	Potassium	111-120	BCL2, apoptosis regulator	Rattus norvegicus	74-79
12107341-9	2001	Expression of bax mRNA in potassium-depleted and potassium-repleted rats tended to increase, while ratios of bcl-2 mRNA to bax mRNA significantly decreased.	Potassium	26-35	BCL2 associated X, apoptosis regulator	Rattus norvegicus	14-17
12107341-9	2001	Expression of bax mRNA in potassium-depleted and potassium-repleted rats tended to increase, while ratios of bcl-2 mRNA to bax mRNA significantly decreased.	Potassium	49-58	BCL2 associated X, apoptosis regulator	Rattus norvegicus	14-17
11164042-4	2000	Using a maximum likelihood (ML) estimator (GY94) we found a positive correlation between Ks and GC4 and only a weak correlation between Ka and Ks, lower than expected under neutral expectations.	Potassium	89-91	N-myc downstream regulated 1	Homo sapiens	96-99
11697077-8	2001	In particular, high level expressions have been achieved for potassium (Shaker B, Kv1.2 and Kv1.3) and sodium (P mu 1.2) channels, and we also demonstrate efficient metabolic labeling of the calcium channel auxiliary beta 3 subunit.	Potassium	61-70	potassium channel, voltage gated shaker related subfamily A, member 2 L homeolog	Xenopus laevis	82-87
11697077-8	2001	In particular, high level expressions have been achieved for potassium (Shaker B, Kv1.2 and Kv1.3) and sodium (P mu 1.2) channels, and we also demonstrate efficient metabolic labeling of the calcium channel auxiliary beta 3 subunit.	Potassium	61-70	potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog	Xenopus laevis	92-97
11158535-8	2001	Surprisingly, the trh1 phenotype was not restored when mutant seedlings were grown at high external potassium concentrations.	Potassium	100-109	Potassium transporter family protein	Arabidopsis thaliana	18-22
11164042-14	2000	We show, for example, that the positive correlation between GC4 and Ks is probably in part a mutational bias, there being more methyl induced CpG--&gt;TpG mutations in GC rich regions.	Potassium	68-70	N-myc downstream regulated 1	Homo sapiens	60-63
11090980-0	2000	Nitric oxide increases excitability by depressing a calcium activated potassium current in snail neurons.	Potassium	70-79	snail family transcriptional repressor 1	Homo sapiens	91-96
11146115-4	2000	In differentiated synapsin-II-overexpressing and control cells, the application of high potassium induced strong intracellular calcium elevation along neurites and varicosities after differentiation and a weak calcium rise in the cell bodies.	Potassium	88-97	synapsin II	Mus musculus	18-29
11085910-1	2000	We examined the effect of glial cell line-derived neurotrophic factor (GDNF) upon nigrostriatal dopaminergic function in response to two-pulse potassium (K(+)) stimulation in rats under in vivo microdialysis conditions.	Potassium	143-152	glial cell derived neurotrophic factor	Rattus norvegicus	26-69
11087258-0	2000	Mechanisms of I(Ks) suppression in LQT1 mutants.	Potassium	16-18	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	35-39
11087258-2	2000	KvLQT1 mutations prolong Q-T by reducing the repolarizing cardiac current [slow delayed rectifier K(+) current (I(Ks) )], but, for reasons that are not well understood, the clinical phenotypes may vary considerably even for carriers of the same mutation, perhaps explaining the mode of inheritance.	Potassium	114-116	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-6
11085910-1	2000	We examined the effect of glial cell line-derived neurotrophic factor (GDNF) upon nigrostriatal dopaminergic function in response to two-pulse potassium (K(+)) stimulation in rats under in vivo microdialysis conditions.	Potassium	143-152	glial cell derived neurotrophic factor	Rattus norvegicus	71-75
11110805-7	2000	Another population of astrocytes is characterized by a relatively symmetric potassium current pattern, comprising outward I(Kdr), I(Ka), and abundant inward potassium currents (I(Kin)), and a larger membrane capacitance (C(m)) and more negative resting membrane potential (RMP) than ORAs.	Potassium	76-85	kinase insert domain receptor	Rattus norvegicus	124-127
11110813-0	2000	Differential changes of potassium currents in CA1 pyramidal neurons after transient forebrain ischemia.	Potassium	24-33	carbonic anhydrase 1	Homo sapiens	46-49
11102461-5	2000	The MOR internalization is dose-dependent, with a similar dose-response to that observed for opioid-induced increases in potassium conductance.	Potassium	121-130	opioid receptor mu 1	Homo sapiens	4-7
11110813-5	2000	The amplitude of total potassium current in CA1 neurons increased approximately 30% following reperfusion.	Potassium	23-32	carbonic anhydrase 1	Homo sapiens	44-47
11110813-11	2000	The present study demonstrates the differential changes of potassium currents in CA1 neurons after reperfusion.	Potassium	59-68	carbonic anhydrase 1	Homo sapiens	81-84
11204450-8	2000	Transforming growth factor beta (TGFbeta), polyunsaturated fatty acids and the glucose-insulin-potassium regimen can antagonize the harmful actions of TNFalpha and protect the myocardium.	Potassium	95-104	tumor necrosis factor	Homo sapiens	151-159
11082455-7	2000	The membrane depolarization induced by elevating the potassium (K(+)) concentration in medium (high K(+)) caused the activation of c-fos and BDNF genes, which was also repressed by permethrin.	Potassium	53-62	FBJ osteosarcoma oncogene	Mus musculus	131-136
11149131-9	2000	Dan Darrow extended our understanding of how body fluids react to hyper- and hyponatremia and to potassium deficiency.	Potassium	97-106	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
11211125-4	2000	Acidification of cytosolic pH (pHi) increased IKs but decreased 1K whereas intracellular alkalinization decreased I(Ks) but increased IK.	Potassium	47-49	glucose-6-phosphate isomerase	Homo sapiens	31-34
11082455-7	2000	The membrane depolarization induced by elevating the potassium (K(+)) concentration in medium (high K(+)) caused the activation of c-fos and BDNF genes, which was also repressed by permethrin.	Potassium	53-62	brain derived neurotrophic factor	Mus musculus	141-145
11211109-8	2000	Potassium balance measured by microdialysis shifted from a net release to a net uptake in response to insulin, with no difference between SCI and H. In conclusion, the mechanism by which insulin mediates an increase in skeletal muscle blood flow is not due to a CNS recruitment of sympathetic vasodilatory nervous activity.	Potassium	0-9	insulin	Homo sapiens	102-109
11211109-8	2000	Potassium balance measured by microdialysis shifted from a net release to a net uptake in response to insulin, with no difference between SCI and H. In conclusion, the mechanism by which insulin mediates an increase in skeletal muscle blood flow is not due to a CNS recruitment of sympathetic vasodilatory nervous activity.	Potassium	0-9	insulin	Homo sapiens	187-194
11058539-8	2000	In cell-free assays, processing of pro-interleukin-1beta and proteolysis of cellular actin by recombinant caspase-1 and caspase-3, respectively, were suppressed by the presence of 150 mM potassium.	Potassium	187-196	caspase 1	Mus musculus	106-115
11058539-8	2000	In cell-free assays, processing of pro-interleukin-1beta and proteolysis of cellular actin by recombinant caspase-1 and caspase-3, respectively, were suppressed by the presence of 150 mM potassium.	Potassium	187-196	caspase 3	Mus musculus	120-129
11101141-5	2000	The numbers of synonymous substitutions per site (Ks) between human and the chimpanzee, gorilla and orangutan for ZFY gene were 0.026, 0.033, and 0.085, respectively.	Potassium	50-52	zinc finger protein Y-linked	Homo sapiens	114-117
11205046-3	2000	The physiological role of Kir channels is to modulate the excitability and secretion of potassium (K+) to maintain K+ homeostasis, under the control of various intracellular second messengers.	Potassium	88-97	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	26-29
11167915-3	2000	Release of CGRP by capsaicin or by high potassium concentration was concentration-dependent and counteracted in calcium-free medium.	Potassium	40-49	calcitonin related polypeptide alpha	Homo sapiens	11-15
11196473-6	2000	Both hCYP11B2 and hCYP11B1 driven reporter constructs responded in a similar manner to treatment with angiotensin II, potassium, dbcAMP, or forskolin.	Potassium	118-127	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	5-13
11196473-6	2000	Both hCYP11B2 and hCYP11B1 driven reporter constructs responded in a similar manner to treatment with angiotensin II, potassium, dbcAMP, or forskolin.	Potassium	118-127	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	18-26
11044229-0	2000	ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure.	Potassium	59-68	angiotensin I converting enzyme	Homo sapiens	0-3
11101141-6	2000	In contrast, the Ks value between human and hominoid primates for the ZFX gene was 0.008 for each comparison.	Potassium	17-19	zinc finger protein X-linked	Homo sapiens	70-73
11059899-2	2000	In the present microdialysis study, performed in the awake rat, we demonstrate a bilateral 4- to 6-fold increase of the potassium-induced release of CCK-like immunoreactivity (CCK-LI) in the ACC 2-3 weeks after a unilateral transection of the sciatic nerve (axotomy), an animal model of phantom limb or deafferentiation pain.	Potassium	120-129	cholecystokinin	Rattus norvegicus	149-152
11059899-2	2000	In the present microdialysis study, performed in the awake rat, we demonstrate a bilateral 4- to 6-fold increase of the potassium-induced release of CCK-like immunoreactivity (CCK-LI) in the ACC 2-3 weeks after a unilateral transection of the sciatic nerve (axotomy), an animal model of phantom limb or deafferentiation pain.	Potassium	120-129	cholecystokinin	Rattus norvegicus	176-179
11026449-9	2000	Heterologous expression of the proteins encoded by the mutant KCNA1 genes suggest that the four point mutations impair delayed-rectifier type potassium currents by different mechanisms.	Potassium	142-151	potassium voltage-gated channel subfamily A member 1	Homo sapiens	62-67
10878016-6	2000	This KCC1 mRNA is substantially increased by potassium depletion but only minimally by sodium depletion.	Potassium	45-54	solute carrier family 12 member 4	Rattus norvegicus	5-9
10878016-8	2000	Potassium depletion but not sodium depletion resulted in an increase in KCC1 protein expression in basolateral membrane.	Potassium	0-9	solute carrier family 12 member 4	Rattus norvegicus	72-76
11027209-5	2000	Expression of wild-type and mutant TWK-18 channels in Xenopus oocytes showed that mutant channels express much larger potassium currents than wild-type channels.	Potassium	118-127	TWiK family of potassium channels protein 18	Caenorhabditis elegans	35-41
11010818-9	2000	Upon potassium depletion of Hep2 cells, EGF-induced EGFR endocytosis was inhibited.	Potassium	5-14	epidermal growth factor receptor	Homo sapiens	52-56
11010818-11	2000	The EGFR was weakly tyrosine phosphorylated by potassium depletion even in the absence of EGF, and this activation resulted in detectable activation of MAPK.	Potassium	47-56	epidermal growth factor receptor	Homo sapiens	4-8
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	75-84	solute carrier family 12 member 4	Rattus norvegicus	24-28
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	75-84	solute carrier family 12 member 4	Rattus norvegicus	48-52
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	203-212	solute carrier family 12 member 4	Rattus norvegicus	24-28
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	203-212	solute carrier family 12 member 4	Rattus norvegicus	48-52
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	203-212	solute carrier family 12 member 4	Rattus norvegicus	24-28
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	203-212	solute carrier family 12 member 4	Rattus norvegicus	48-52
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	203-212	solute carrier family 12 member 4	Rattus norvegicus	24-28
10878016-9	2000	The increase of colonic KCC1 mRNA abundance and KCC1 protein expression in potassium depletion of the rat colonic basolateral membrane suggests that K-Cl cotransporter: 1) is involved in transepithelial potassium absorption and 2) regulates the increase in potassium absorption induced by dietary potassium depletion.	Potassium	203-212	solute carrier family 12 member 4	Rattus norvegicus	48-52
10878016-10	2000	We conclude that active potassium absorption in the rat distal colon involves the coordinated regulation of both apical membrane H,K-ATPase and basolateral membrane KCC1 protein.	Potassium	24-33	solute carrier family 12 member 4	Rattus norvegicus	165-169
10986350-1	2000	Previous studies in our laboratory using rat brain tissue have shown that neuropeptide Y (NPY) can enhance NMDA- and potassium-stimulated dopamine release from various brain regions and that this enhancement is reversed by sigma (sigma) receptor antagonists.	Potassium	117-126	neuropeptide Y	Rattus norvegicus	74-88
10998345-1	2000	Effects of insulin-like growth factor I (IGF-I) and insulin on glucose and potassium fluxes were examined by measuring transhepatic glucose and potassium balance in isolated perfused rat livers.	Potassium	75-84	insulin-like growth factor 1	Rattus norvegicus	41-46
10998345-5	2000	Both IGF-I and insulin induced net potassium uptake, while insulin also attenuated the response to adrenaline.	Potassium	35-44	insulin-like growth factor 1	Rattus norvegicus	5-10
10998345-6	2000	In conclusion, IGF-I causes (i) insulin-like inhibition of hepatic glycogenolysis, even at low, nanomolar concentrations, which is associated with decreased cAMP release, reduced in the absence of Ca(2+), but not mediated by phosphoinositide 3-kinase, (ii) reduction of adrenaline-induced glycogenolysis and (iii) net potassium uptake under basal conditions.	Potassium	318-327	insulin-like growth factor 1	Rattus norvegicus	15-20
11105970-16	2000	Patients in the lowest quartile of the KS showed a more than 20-fold increased risk of having mean HbA1c values &gt; or = 7.0% as opposed to those in the highest quartile (odds ratio, OR=23.3;p=0.009).	Potassium	39-41	hemoglobin subunit alpha 1	Homo sapiens	99-103
11409912-7	2000	Therefore, FGF-2 induces KS-like spindle cells to acquire properties characteristic of transformed cells.	Potassium	25-27	fibroblast growth factor 2	Mus musculus	11-16
11409912-8	2000	This suggests that FGF-2 plays a pathogenetic role in KS not only by promoting angiogenesis, but also by conferring a transformed phenotype upon KS cells.	Potassium	54-56	fibroblast growth factor 2	Mus musculus	19-24
11409912-8	2000	This suggests that FGF-2 plays a pathogenetic role in KS not only by promoting angiogenesis, but also by conferring a transformed phenotype upon KS cells.	Potassium	145-147	fibroblast growth factor 2	Mus musculus	19-24
11409912-9	2000	In light of previous reports on Tat-induced release of FGF-2 into the extracellular space, our findings may provide an additional mechanism for the observed synergism between Tat and FGF-2 in the pathogenesis of KS.	Potassium	212-214	fibroblast growth factor 2	Mus musculus	55-60
11409912-9	2000	In light of previous reports on Tat-induced release of FGF-2 into the extracellular space, our findings may provide an additional mechanism for the observed synergism between Tat and FGF-2 in the pathogenesis of KS.	Potassium	212-214	fibroblast growth factor 2	Mus musculus	183-188
10986350-1	2000	Previous studies in our laboratory using rat brain tissue have shown that neuropeptide Y (NPY) can enhance NMDA- and potassium-stimulated dopamine release from various brain regions and that this enhancement is reversed by sigma (sigma) receptor antagonists.	Potassium	117-126	neuropeptide Y	Rattus norvegicus	90-93
10986350-3	2000	We compare mechanisms by which the prototypical sigma receptor agonist (+)-pentazocine, and the proposed endogenous sigma receptor ligand NPY regulate potassium-stimulated [(3)H]dopamine release from SH-SY5Y cells.	Potassium	151-160	neuropeptide Y	Homo sapiens	138-141
10966933-0	2000	Potassium deprivation upregulates expression of renal basolateral Na(+)-HCO(3)(-) cotransporter (NBC-1).	Potassium	0-9	solute carrier family 4 member 4	Rattus norvegicus	97-102
10993771-4	2000	Exposure of endothelial cells to isoproterenol, high extracellular potassium, or cadmium, all of which stimulate peptide secretion via different signaling pathways, significantly (P &gt; 0.001) increased the secretion of both ANG II and ET-1 in a cell size-dependent manner.	Potassium	67-76	angiotensinogen	Homo sapiens	226-232
10993771-4	2000	Exposure of endothelial cells to isoproterenol, high extracellular potassium, or cadmium, all of which stimulate peptide secretion via different signaling pathways, significantly (P &gt; 0.001) increased the secretion of both ANG II and ET-1 in a cell size-dependent manner.	Potassium	67-76	endothelin 1	Homo sapiens	237-241
11058023-5	2000	Variable activities of G6PD and PK, probably related to different reticulocyte number, were detected together with normal osmotic fragility and intracellular sodium and potassium concentrations.	Potassium	169-178	glucose-6-phosphate dehydrogenase	Canis lupus familiaris	23-27
11085315-8	2000	In rats treated with METH followed 7 days later with GDNF, there were significant increases in potassium- and amphetamine-evoked overflow of DA on the right, GDNF-treated, side of the brain compared to the left side.	Potassium	95-104	glial cell derived neurotrophic factor	Rattus norvegicus	53-57
11085315-8	2000	In rats treated with METH followed 7 days later with GDNF, there were significant increases in potassium- and amphetamine-evoked overflow of DA on the right, GDNF-treated, side of the brain compared to the left side.	Potassium	95-104	glial cell derived neurotrophic factor	Rattus norvegicus	158-162
10966933-1	2000	The purpose of the present experiments was to examine the effect of potassium deprivation on the expression of the renal basolateral Na(+)-HCO(3)(-) cotransporter (NBC-1).	Potassium	68-77	solute carrier family 4 member 4	Rattus norvegicus	164-169
10962170-5	2000	We have found that Kv9.1 isolated from a rat brain cDNA library alters the kinetics and the voltage-dependence of activation and inactivation of Kv2.1, a channel subunit that generates slowly inactivating delayed rectifier potassium currents.	Potassium	223-232	potassium voltage-gated channel, modifier subfamily S, member 1	Rattus norvegicus	19-24
10964095-10	2000	Because the bFGF-induced murine vascular network is analogous to the abundant vascularity present in AIDS-KS lesions, this murine model should provide an excellent vehicle for numerous clinically relevant studies, such as assessment of drug clearance at AIDS-KS lesional sites.	Potassium	106-108	fibroblast growth factor 2	Mus musculus	12-16
11092145-2	2000	Various conventional therapies including intravenous sodium bicarbonate, insulin with glucose and several beta-2 agonists are commonly employed as transient measures to enhance shift of potassium from the extracellular to the intracellular compartment.	Potassium	186-195	insulin	Homo sapiens	73-80
11092145-2	2000	Various conventional therapies including intravenous sodium bicarbonate, insulin with glucose and several beta-2 agonists are commonly employed as transient measures to enhance shift of potassium from the extracellular to the intracellular compartment.	Potassium	186-195	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	106-112
11016327-1	2000	BACKGROUND: The bradykinin (BK)-induced endothelium-dependent relaxation is impaired in the presence of elevated potassium concentration enhancing the vasospastic tendency of large coronary arteries.	Potassium	113-122	kininogen 1	Homo sapiens	16-26
11016327-1	2000	BACKGROUND: The bradykinin (BK)-induced endothelium-dependent relaxation is impaired in the presence of elevated potassium concentration enhancing the vasospastic tendency of large coronary arteries.	Potassium	113-122	kininogen 1	Homo sapiens	28-30
10962170-5	2000	We have found that Kv9.1 isolated from a rat brain cDNA library alters the kinetics and the voltage-dependence of activation and inactivation of Kv2.1, a channel subunit that generates slowly inactivating delayed rectifier potassium currents.	Potassium	223-232	potassium voltage-gated channel subfamily B member 1	Rattus norvegicus	145-150
10980526-10	2000	Expression patterns in mouse and rat cochlea indicate that Connexin26 and Connexin30 are expressed in the supportive cells of the cochlea, suggesting a potential role in endolymph potassium recycling.	Potassium	180-189	gap junction protein, beta 2	Rattus norvegicus	59-69
10975407-3	2000	In a medium of Sodium, Potassium, and Magnesium [NKM] that supported active sperm motility, pHi was 6.9.	Potassium	23-32	glucose-6-phosphate isomerase	Bos taurus	92-95
10962015-2	2000	When expressed alone in heterologous expression systems, KvLQT1 channels exhibit a rapidly activating potassium current that slowly deactivates.	Potassium	102-111	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	57-63
10962015-5	2000	Coexpression of KvLQT1 with a MinK COOH-terminus deletion mutant (MinK DeltaCterm) in Xenopus oocytes resulted in a rapidly activated potassium current closely resembling currents recorded from oocytes expressing KvLQT1 alone, indicating that this region is necessary for modulation.	Potassium	134-143	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	16-22
10974659-8	2000	CART-LI was released from hypothalamic tissue slices in a calcium-dependent fashion by potassium-induced depolarisation.	Potassium	87-96	CART prepropeptide	Rattus norvegicus	0-4
10964491-8	2000	However, cortical cell survival increased upon depolarization with elevated potassium; an effect known to involve the induction of an autocrine BDNF loop.	Potassium	76-85	brain derived neurotrophic factor	Homo sapiens	144-148
10960688-0	2000	Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse.	Potassium	22-31	reciprocal translocation, Chr 16, cytogenetic band C3-4; and Chr 17, cytogenetic band A2, Davisson 65	Mus musculus	86-96
10980011-10	2000	Finally, big conductance calcium-activated potassium current (MaxiK(+)) was identified in area postrema neurons (n = 12/12).	Potassium	43-52	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	62-67
10972664-0	2000	CCKB/gastrin receptors mediate changes in sodium and potassium absorption in the isolated perfused rat kidney.	Potassium	53-62	gastrin	Rattus norvegicus	5-12
10972664-12	2000	Gastrin decreased urinary potassium excretion at 10-8 and 10-6 mol/L [maximal decrease at 10-6 mol/L from baseline values (100%) to 49% after 10 minutes and to 69% after 20 minutes, P &lt; 0.05, N = 6].	Potassium	26-35	gastrin	Rattus norvegicus	0-7
11021476-6	2000	Functional analyses of the mutant KCNQ1 subunit on COS7 cells revealed its functional channels in the homozygous state, producing a significantly smaller current than the KCNQ1 channels and a less severe dominant-negative effect on I(Ks).	Potassium	234-236	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	34-39
11021476-6	2000	Functional analyses of the mutant KCNQ1 subunit on COS7 cells revealed its functional channels in the homozygous state, producing a significantly smaller current than the KCNQ1 channels and a less severe dominant-negative effect on I(Ks).	Potassium	234-236	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	171-176
11021476-7	2000	The novel KCNQ1 mutation R259C is the molecular basis for I(Ks) dysfunction underlying an apparently sporadic case of hypokalemia-induced LQTS, consistent with a mild mutation likely to disclose the clinical manifestation of LQTS in a context of severe hypokalemia.	Potassium	60-62	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	10-15
10931813-3	2000	Chromanol 293B (30 micromol/L) was used to block I(Ks) (LQT1 model).	Potassium	51-53	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	56-60
10971617-3	2000	Forskolin treatment and depolarization with potassium plus BayK 8644 led to significant increases in secretogranin II mRNA in the principal cells of the hippocampus.	Potassium	44-53	secretogranin II	Rattus norvegicus	101-117
10974488-8	2000	The injection of ANGII into the LV reduced the sodium, potassium and urinary volume.	Potassium	55-64	angiotensinogen	Rattus norvegicus	17-22
10974488-9	2000	Previous treatment with clonidine attenuated the action of ANGII in reducing the sodium, potassium and urinary volume, whereas previous treatment with yohimbine attenuated the effects of ANGII but with less intensity than that caused by clonidine.	Potassium	89-98	angiotensinogen	Rattus norvegicus	59-64
10931811-0	2000	G-Protein beta(3)-subunit 825T allele is associated with enhanced human atrial inward rectifier potassium currents.	Potassium	96-105	G protein subunit beta 3	Homo sapiens	0-25
10918305-4	2000	Here, a new model is proposed in which glutamate uptake via the excitatory amino acid transporter (EAAT) is functionally coupled to other glial transporters, in particular the sodium-bicarbonate cotransporter (NBC) and the monocarboxylate transporter (MCT), as well as other glial functions, such as calcium signalling, a high potassium conductance and CO(2) consumption.	Potassium	327-336	solute carrier family 16 member 1	Homo sapiens	223-250
10974488-3	2000	The present experiments were conducted to investigate the role of the alpha-adrenergic antagonists and agonistic injected into the LH on the water intake, sodium and potassium excretion elicited by injections of ANGII into the lateral ventricle (LV).	Potassium	166-175	angiotensinogen	Rattus norvegicus	212-217
10903988-0	2000	Knockout blow for channel identity crisis : vasodilation to potassium is mediated via Kir2.1.	Potassium	60-69	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	86-92
10801833-1	2000	Epidermal growth factor (EGF) inhibits carbachol-induced chloride secretion in T(84) colonic epithelial cells and has been shown to activate phosphatidylinositol (PI) 3-kinase, leading to inhibition of a basolateral potassium conductance.	Potassium	216-225	epidermal growth factor	Homo sapiens	0-23
10801833-1	2000	Epidermal growth factor (EGF) inhibits carbachol-induced chloride secretion in T(84) colonic epithelial cells and has been shown to activate phosphatidylinositol (PI) 3-kinase, leading to inhibition of a basolateral potassium conductance.	Potassium	216-225	epidermal growth factor	Homo sapiens	25-28
10899967-4	2000	Combined treatment with forskolin and elevated potassium significantly increased expression of both endogenous PPT mRNA and the PPT promoter-GFP construct.	Potassium	47-56	tachykinin, precursor 1	Rattus norvegicus	111-114
10899967-4	2000	Combined treatment with forskolin and elevated potassium significantly increased expression of both endogenous PPT mRNA and the PPT promoter-GFP construct.	Potassium	47-56	tachykinin, precursor 1	Rattus norvegicus	128-131
10964617-0	2000	Enhanced proliferation and potassium conductance of Schwann cells isolated from NF2 schwannomas can be reduced by quinidine.	Potassium	27-36	NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor	Homo sapiens	80-83
10918552-7	2000	Potassium excretion was diminished in African-Americans (P &lt; 0.001 to P = 0.002), and in a multivariate analysis, potassium excretion was the strongest correlate of kallikrein excretion (T = 4.10, P = 0.0001).	Potassium	0-9	kallikrein related peptidase 4	Homo sapiens	168-178
10884308-2	2000	In the present study, using specific antibodies and antisense oligodeoxynucleotides, we show that this proliferation-dependent potassium current is mediated by the Shaker potassium channel Kv1.5.	Potassium	127-136	potassium voltage-gated channel subfamily A member 5	Homo sapiens	189-194
12147952-0	2000	Differential effects of direct antagonism of AII compared to ACE inhibitors on serum potassium levels and azotemia in patients with severe congestive heart failure.	Potassium	85-94	NLR family pyrin domain containing 3	Homo sapiens	45-48
10918552-7	2000	Potassium excretion was diminished in African-Americans (P &lt; 0.001 to P = 0.002), and in a multivariate analysis, potassium excretion was the strongest correlate of kallikrein excretion (T = 4.10, P = 0.0001).	Potassium	117-126	kallikrein related peptidase 4	Homo sapiens	168-178
10918552-9	2000	CONCLUSIONS: Kallikrein excretion is influenced by several independent determinants, both hereditary (gender, ethnicity, and genetic risk of hypertension) and environmental (potassium intake and excretion).	Potassium	174-183	kallikrein related peptidase 4	Homo sapiens	13-23
10918552-10	2000	Ethnicity and environment may interact uniquely to influence kallikrein, as demonstrated by the case of African-Americans with diminutions of both kallikrein and potassium excretion.	Potassium	162-171	kallikrein related peptidase 4	Homo sapiens	61-71
10965228-1	2000	We examined whether the formation or the release of the vasodilators adenosine, prostacyclin (PGI(2)) and potassium (K(+)) increase in skeletal muscle interstitium in response to nitric oxide synthase (NOS) inhibition.	Potassium	106-115	nitric oxide synthase 2	Homo sapiens	179-200
10882483-4	2000	Heterologous expression of rat eag2 in HEK-293 cells gave rise to a voltage-gated, noninactivating potassium current, active at the cells" resting potential and blocked by low nanomolar concentrations of cytosolic calcium.	Potassium	99-108	potassium voltage-gated channel subfamily H member 5	Rattus norvegicus	31-35
10854586-0	2000	Potassium depolarization-induced cAMP stimulates somatostatin mRNA levels in cultured diencephalic neurons.	Potassium	0-9	somatostatin	Homo sapiens	49-61
10764815-10	2000	Furthermore, potassium depolarization induced the tyrosine phosphorylation of both RAFTK and paxillin in an intracellular Ca(2+)-dependent manner in the differentiated PC12 cells.	Potassium	13-22	paxillin	Rattus norvegicus	93-101
10777497-5	2000	Growth of the psr1psr2 mutant is severely inhibited under conditions of sodium but not potassium ion or sorbitol stress.	Potassium	87-96	phosphatase	Saccharomyces cerevisiae S288C	14-22
10854586-3	2000	We have previously demonstrated in fetal cerebrocortical cells, that somatostatin (SS) mRNA levels can be induced by depolarizing agents such as high potassium concentrations and veratridine (VTD), and that these effects are calcium dependent.	Potassium	150-159	somatostatin	Homo sapiens	69-81
10854586-3	2000	We have previously demonstrated in fetal cerebrocortical cells, that somatostatin (SS) mRNA levels can be induced by depolarizing agents such as high potassium concentrations and veratridine (VTD), and that these effects are calcium dependent.	Potassium	150-159	somatostatin	Homo sapiens	83-85
10833427-2	2000	Functional expression of Kir 6.2 and Kir 6.1 can complement growth deficiency weakly and strongly respectively of the yeast strain on low-potassium medium.	Potassium	138-147	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	25-32
10833427-2	2000	Functional expression of Kir 6.2 and Kir 6.1 can complement growth deficiency weakly and strongly respectively of the yeast strain on low-potassium medium.	Potassium	138-147	potassium inwardly rectifying channel subfamily J member 8	Homo sapiens	37-44
10912758-6	2000	The alpha-adducin gene remained a significant independent predictor of hypertension in a multivariate logistic model even after correcting for other risk factors for hypertension, including gender, age, body mass index (BMI), smoking, LDL cholesterol, triglycerides, urine sodium (Na), and urine potassium (K), (OR = 1.55, 95% CI = 1.03, 2.34).	Potassium	296-305	adducin 1	Homo sapiens	4-17
10836979-6	2000	Like ROMK, BSC-1 protein content was found to decrease significantly in the renal medulla of potassium-deprived rats.	Potassium	93-102	solute carrier family 12 member 1	Rattus norvegicus	11-16
10852238-7	2000	The present results indicate that decreased potassium conductance is involved in the effect of HCRT on LC neurons.	Potassium	44-53	hypocretin neuropeptide precursor	Rattus norvegicus	95-99
10843757-0	2000	A role for potassium in TNF-induced apoptosis and gene-induction in human and rodent tumour cell lines.	Potassium	11-20	tumor necrosis factor	Homo sapiens	24-27
10789833-3	2000	In addition, this work examined the effects of spinal hypothermia on FOS expression induced either by ischemia or by potassium-evoked depolarization (intrathecal KCl).	Potassium	117-126	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	69-72
10835350-4	2000	Interestingly, the disruption of PMP3 exacerbates the NaCl sensitivity phenotype of a mutant strain lacking the Pmr2p/Enap Na(+)-ATPases and the Nha1p Na(+)/H(+) antiporter, and suppresses the potassium dependency of a strain lacking the K(+) transporters, Trk1p and Trk2p.	Potassium	193-202	Pmp3p	Saccharomyces cerevisiae S288C	33-37
10843757-1	2000	Rat/mouse T cell hybridoma-derived PC60 R55/R75 cells were used as a model to study the role of intracellular potassium in TNF-induced apoptosis and gene induction.	Potassium	110-119	tumor necrosis factor	Mus musculus	123-126
10843757-2	2000	A reduction of intracellular potassium with nigericin or valinomycin (ionophores), or ouabain (Na(+)/K(+)-ATPase inhibitor) sensitized PC60 R55/R75 cells to TNF-induced apoptosis.	Potassium	29-38	tumor necrosis factor	Homo sapiens	157-160
10843757-5	2000	These results suggest a role for intracellular potassium in TNF-induced apoptosis and gene induction.	Potassium	47-56	tumor necrosis factor	Homo sapiens	60-63
10886343-1	2000	In the hippocampus of patients with therapy-refractory temporal lobe epilepsy, glial cells of area CA1 might be less able to take up potassium ions via barium-sensitive inwardly rectifying and voltage-independent potassium channels.	Potassium	133-142	carbonic anhydrase 1	Homo sapiens	99-102
10828036-3	2000	Two tumorigenic AIDS-KS cell lines, KS Y-1 and KS-imm, expressed 4560 and 9480 IL-13 binding sites per cell with an affinity (kd) of approximately 0.9 and 3.7 nmol/L, respectively.	Potassium	21-23	interleukin 13	Homo sapiens	79-84
10828036-3	2000	Two tumorigenic AIDS-KS cell lines, KS Y-1 and KS-imm, expressed 4560 and 9480 IL-13 binding sites per cell with an affinity (kd) of approximately 0.9 and 3.7 nmol/L, respectively.	Potassium	36-38	interleukin 13	Homo sapiens	79-84
10828036-3	2000	Two tumorigenic AIDS-KS cell lines, KS Y-1 and KS-imm, expressed 4560 and 9480 IL-13 binding sites per cell with an affinity (kd) of approximately 0.9 and 3.7 nmol/L, respectively.	Potassium	36-38	interleukin 13	Homo sapiens	79-84
10828036-7	2000	Daily IT treatment with 250 microg/kg of IL-13 toxin in another KS-derived cell line also produced complete responses.	Potassium	64-66	interleukin 13	Homo sapiens	41-46
10828036-8	2000	Twice daily intraperitoneal injections of IL13-PE38QQR (25 or 50 microg/kg per dose) for 10 days (total injections = 20) also completely eradicated KS Y-1 tumors.	Potassium	148-150	interleukin 13	Homo sapiens	42-46
10797620-7	2000	In vivo, the intracerebroventricular administration of IFN-gamma, but not TNF-alpha, to healthy rats led to an almost complete disappearance of KS-IR from ramified brain microglia.	Potassium	144-146	interferon gamma	Rattus norvegicus	55-64
10804231-7	2000	Given the pharmacological properties of potassium homeostasis (sensitivity to Cs(+)), members of the ether-a-go-go (ERG) channel family widely expressed in the nervous system could underlie part of the process.	Potassium	40-49	ETS transcription factor ERG	Homo sapiens	101-114
10847588-12	2000	These data together indicate that TASK contributes to the generation of high resting potassium permeability of glomerulosa cells, and this background K+ channel may be a target of hormonal regulation.	Potassium	85-94	potassium two pore domain channel subfamily K member 3	Rattus norvegicus	34-38
10799869-1	2000	We report that potassium leakage from cells leads to activation of the Ca2+-independent phospholipase A2 (iPLA2), and the latter plays a pivotal role in regulating the cleavage of pro-IL-1 beta by the IL-converting enzyme caspase-1 in human monocytes.	Potassium	15-24	phospholipase A2 group VI	Homo sapiens	71-104
10799869-1	2000	We report that potassium leakage from cells leads to activation of the Ca2+-independent phospholipase A2 (iPLA2), and the latter plays a pivotal role in regulating the cleavage of pro-IL-1 beta by the IL-converting enzyme caspase-1 in human monocytes.	Potassium	15-24	phospholipase A2 group VI	Homo sapiens	106-111
10799869-1	2000	We report that potassium leakage from cells leads to activation of the Ca2+-independent phospholipase A2 (iPLA2), and the latter plays a pivotal role in regulating the cleavage of pro-IL-1 beta by the IL-converting enzyme caspase-1 in human monocytes.	Potassium	15-24	interleukin 1 beta	Homo sapiens	180-193
10799869-1	2000	We report that potassium leakage from cells leads to activation of the Ca2+-independent phospholipase A2 (iPLA2), and the latter plays a pivotal role in regulating the cleavage of pro-IL-1 beta by the IL-converting enzyme caspase-1 in human monocytes.	Potassium	15-24	caspase 1	Homo sapiens	222-231
10804231-7	2000	Given the pharmacological properties of potassium homeostasis (sensitivity to Cs(+)), members of the ether-a-go-go (ERG) channel family widely expressed in the nervous system could underlie part of the process.	Potassium	40-49	ETS transcription factor ERG	Homo sapiens	116-119
10804231-9	2000	Specific ERG blockers (dofetilide and E 4031) inhibited hyperpolarization- and depolarization-activated glial currents, and ERG blockade impaired clearance of extracellular potassium with little direct effect on hippocampal neuron excitability.	Potassium	173-182	ETS transcription factor ERG	Homo sapiens	124-127
10804231-14	2000	This study provides insight into a possible physiological role of hippocampal ERG channels and links activation of ERG to control of potassium homeostasis.	Potassium	133-142	ETS transcription factor ERG	Homo sapiens	78-81
10804231-14	2000	This study provides insight into a possible physiological role of hippocampal ERG channels and links activation of ERG to control of potassium homeostasis.	Potassium	133-142	ETS transcription factor ERG	Homo sapiens	115-118
10767668-5	2000	Minerals such as magnesium, calcium, potassium, zinc, chromium, and vanadium appear to have associations with insulin resistance or its management.	Potassium	37-46	insulin	Homo sapiens	110-117
10841341-4	2000	Treatment of cerebellar granule cells with various antibodies raised against different epitopes of APPs and A beta oppositely modulates low potassium apoptotic cell death.	Potassium	140-149	amyloid beta precursor protein	Rattus norvegicus	108-114
10753559-4	2000	It is concluded that potassium currents may contribute to the modulation of Gal myotropic activity in the gut.	Potassium	21-30	galanin and GMAP prepropeptide	Rattus norvegicus	76-79
10793021-4	2000	We hypothesized that specific changes in the expression of the secretory renal outer medullary potassium channel (ROMK), and the potassium channel regulator, channel-inducing factor (CHIF), in kidney and colon could contribute to changes in potassium handling.	Potassium	95-104	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	114-118
10793021-4	2000	We hypothesized that specific changes in the expression of the secretory renal outer medullary potassium channel (ROMK), and the potassium channel regulator, channel-inducing factor (CHIF), in kidney and colon could contribute to changes in potassium handling.	Potassium	95-104	FXYD domain containing ion transport regulator 4	Homo sapiens	183-187
10793021-15	2000	In conclusion, (1) suppression of ROMK and CHIF in the kidney may contribute to decreased renal potassium excretion in ARF; (2) enhanced expression of CHIF in the distal colon in IRI could be an adaptive response to increase potassium excretion in the colon and help modify hyperkalemia in ARF; and (3) increased aldosterone levels, as a response to hyperkalemia, could be upregulating colonic CHIF.	Potassium	96-105	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	34-38
10793021-15	2000	In conclusion, (1) suppression of ROMK and CHIF in the kidney may contribute to decreased renal potassium excretion in ARF; (2) enhanced expression of CHIF in the distal colon in IRI could be an adaptive response to increase potassium excretion in the colon and help modify hyperkalemia in ARF; and (3) increased aldosterone levels, as a response to hyperkalemia, could be upregulating colonic CHIF.	Potassium	96-105	FXYD domain containing ion transport regulator 4	Homo sapiens	43-47
10793021-15	2000	In conclusion, (1) suppression of ROMK and CHIF in the kidney may contribute to decreased renal potassium excretion in ARF; (2) enhanced expression of CHIF in the distal colon in IRI could be an adaptive response to increase potassium excretion in the colon and help modify hyperkalemia in ARF; and (3) increased aldosterone levels, as a response to hyperkalemia, could be upregulating colonic CHIF.	Potassium	225-234	FXYD domain containing ion transport regulator 4	Homo sapiens	151-155
10780946-13	2000	These studies demonstrate that intracellular energy production is important for acute leptin secretion and that potassium and calcium flux may play roles in coupling intracellular energy production to leptin secretion.	Potassium	112-121	leptin	Homo sapiens	201-207
10864003-6	2000	In the presence of calcium reconstituted ICln channels are more permeable to bromide than chloride, and more permeable to potassium than sodium.	Potassium	122-131	chloride nucleotide-sensitive channel 1A pseudogene 1	Homo sapiens	41-45
11232243-0	2000	Inhibition of Na+/K(+)-ATPase may be one mechanism contributing to potassium efflux and cell shrinkage in CD95-induced apoptosis.	Potassium	67-76	Fas cell surface death receptor	Homo sapiens	106-110
10729324-9	2000	In Lis1+/- hippocampus, intense interictal bursting was observed on elevation of extracellular potassium to 6.5 mM, a condition that resulted in only minimal bursting in wild type.	Potassium	95-104	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	Mus musculus	3-7
10928803-5	2000	The loss of connexin 26 in the gap junction complex would expect to disrupt the recycling of potassium from the synapses at the base of hair cells through the supporting cells and fibroblasts of potassium ions back to the high potassium containing endolymph of the cochlear duct and therefore would result in a local intoxication of the Corti s organ by potassium, leading to the hearing loss.	Potassium	93-102	gap junction protein beta 2	Homo sapiens	12-23
10928803-5	2000	The loss of connexin 26 in the gap junction complex would expect to disrupt the recycling of potassium from the synapses at the base of hair cells through the supporting cells and fibroblasts of potassium ions back to the high potassium containing endolymph of the cochlear duct and therefore would result in a local intoxication of the Corti s organ by potassium, leading to the hearing loss.	Potassium	195-204	gap junction protein beta 2	Homo sapiens	12-23
10928803-5	2000	The loss of connexin 26 in the gap junction complex would expect to disrupt the recycling of potassium from the synapses at the base of hair cells through the supporting cells and fibroblasts of potassium ions back to the high potassium containing endolymph of the cochlear duct and therefore would result in a local intoxication of the Corti s organ by potassium, leading to the hearing loss.	Potassium	195-204	gap junction protein beta 2	Homo sapiens	12-23
10928803-5	2000	The loss of connexin 26 in the gap junction complex would expect to disrupt the recycling of potassium from the synapses at the base of hair cells through the supporting cells and fibroblasts of potassium ions back to the high potassium containing endolymph of the cochlear duct and therefore would result in a local intoxication of the Corti s organ by potassium, leading to the hearing loss.	Potassium	195-204	gap junction protein beta 2	Homo sapiens	12-23
10790998-1	2000	S-1 is a novel oral anticancer drug, composed of tegafur (FT), gimestat (CDHP) and otastat potassium (Oxo) in a molar ratio of 1:0.4:1, based on the biochemical modulation of 5-fluorouracil (5-FU).	Potassium	91-100	eukaryotic translation elongation factor 1 alpha 2	Mus musculus	0-3
10686402-0	2000	Potassium currents in CA1 neurons of rat hippocampus increase shortly after transient cerebral ischemia.	Potassium	0-9	carbonic anhydrase 1	Rattus norvegicus	22-25
10793523-4	2000	If the potassium concentration is 60 mEq.l-1, the estimated safe transfusion rate would be 6 ml.min-1 and this can not be agreed with by clinicians who transfuse daily in cases of massive bleeding.	Potassium	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
10793523-5	2000	The calculated safe transfusion rate (10 mEq.hr-1 of potassium load) ranges from 6 to 72 ml.min-1 considering the storage period from the day of gathering and irradiation.	Potassium	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
10921262-2	2000	The most prominent ill effects of ACE inhibitors include hypotension, acute renal impairement in those patients presenting with stenosis of the renal artery or manifest circulatory insufficiency, hyperpotassemia developing because of taking potassium-storing diuretics; cough, Quincke"s edema, headache, syncope, orthostatic hypotension, nausea, diarrhea, skin eruption.	Potassium	241-250	angiotensin I converting enzyme	Homo sapiens	34-37
10784345-3	2000	Expression of hTREK-1 produced a substantial hyperpolarising shift in resting membrane potential accompanied by the induction of large, outwardly rectifying, non-inactivating currents which were potassium selective.	Potassium	195-204	potassium two pore domain channel subfamily K member 2	Homo sapiens	14-21
10686402-1	2000	Total potassium current in CA1 pyramidal neurons was studied using whole-cell voltage-clamp recording technique in hippocampal slices prepared before and at 6-8 h after transient forebrain ischemia.	Potassium	6-15	carbonic anhydrase 1	Rattus norvegicus	27-30
10686402-4	2000	These results indicate that the increase of potassium current might be responsible for the decreased excitability in CA1 neurons after severe ischemia and may be involved in postischemic cell death in hippocampus.	Potassium	44-53	carbonic anhydrase 1	Rattus norvegicus	117-120
10712445-0	2000	HERG-Like potassium current regulates the resting membrane potential in glomus cells of the rabbit carotid body.	Potassium	10-19	potassium voltage-gated channel subfamily H member 2	Homo sapiens	0-4
10716483-4	2000	RESULTS: I(Ks) block with chromanol 293B (LQT1) homogeneously prolonged APD90 of the three cell types without increasing TDR.	Potassium	11-13	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	42-46
10725268-0	2000	Potassium- and acetylcholine-induced vasorelaxation in mice lacking endothelial nitric oxide synthase.	Potassium	0-9	nitric oxide synthase 3, endothelial cell	Mus musculus	68-101
10718918-7	2000	The latter mimicked the effects of NaHS, since it reduced potassium-stimulated CRH release.	Potassium	58-67	corticotropin releasing hormone	Rattus norvegicus	79-82
10736204-3	2000	Short-term (12-48 h) stimulation of cultured Purkinje cells by potassium-induced depolarization or blockade of their inhibitory GABAergic input results in an increased incidence of Purkinje cells with L7/pcp-2 mRNA-positive dendrites and increased levels of L7 protein expression, the latter by a posttranscriptional mechanism.	Potassium	63-72	Purkinje cell protein 2	Homo sapiens	204-209
10677552-3	2000	Cell membrane depolarization induced by increased potassium concentration [K(+)] increased medium concentrations of both AA and LH-RH.	Potassium	50-59	gonadotropin releasing hormone 1	Homo sapiens	128-133
10684659-11	2000	Transfer of label from [(14)C]malonyl-ACP to the nucleophile at position 169 in the KS can be detected for the wild-type enzyme and for the C169S and K341A mutants, but not for the H309A mutant and only very weakly for the H346A mutant.	Potassium	84-86	NADH:ubiquinone oxidoreductase subunit AB1	Homo sapiens	38-41
10684659-12	2000	A model is proposed for decarboxylative priming and extension of a polyketide chain by the KS, where C169 and H346 form a catalytic dyad for acyl chain attachment, H309 positions the malonyl-ACP in the active site and supports carbanion formation by interacting with the thioester carbonyl, and K341 enhances the rate of malonyl-ACP decarboxylation via electrostatic interaction.	Potassium	91-93	NADH:ubiquinone oxidoreductase subunit AB1	Homo sapiens	191-194
10684659-12	2000	A model is proposed for decarboxylative priming and extension of a polyketide chain by the KS, where C169 and H346 form a catalytic dyad for acyl chain attachment, H309 positions the malonyl-ACP in the active site and supports carbanion formation by interacting with the thioester carbonyl, and K341 enhances the rate of malonyl-ACP decarboxylation via electrostatic interaction.	Potassium	91-93	NADH:ubiquinone oxidoreductase subunit AB1	Homo sapiens	329-332
10681443-5	2000	Neuronal expression of the p35 protein was found to confer functional caspase inhibitory activity and prevent apoptosis in isolated cerebellar granular cultures induced to undergo apoptosis either via staurosporine treatment or through withdrawal of extracellular potassium.	Potassium	264-273	interleukin 12a	Mus musculus	27-30
10679789-5	2000	In the presence of bFGF, elevated potassium caused a more differentiated neuronal phenotype, characterized by an increased proportion of MAP-5(+) cells, extensive neuritic branching, and higher specific activity of glutamic acid decarboxylase.	Potassium	34-43	fibroblast growth factor 2	Rattus norvegicus	19-23
10662833-4	2000	On the other hand, the proper identity of the retinal cone Na-Ca exchanger, in terms of both functional characteristics (e.g., requirement for and transport of potassium) and molecular identity, has not yet been elucidated.	Potassium	160-169	nascent polypeptide-associated complex alpha subunit	Gallus gallus	59-64
10737671-0	2000	Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion.	Potassium	24-33	neuropeptide Y	Homo sapiens	0-14
10662833-7	2000	We identified NCKX transcripts in both human and chicken cones and observed strong potassium-dependent Na-Ca exchange activity after heterologous expression of human and chicken cone NCKX cDNAs in cultured insect cells.	Potassium	83-92	nascent polypeptide-associated complex alpha subunit	Gallus gallus	103-108
10701813-0	2000	Human G-protein beta3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure.	Potassium	63-72	G protein subunit beta 3	Homo sapiens	6-21
10701813-10	2000	The T825 allele of GNB3 is associated with increased serum potassium and total cholesterol levels but not with blood pressure in a Japanese population.	Potassium	59-68	G protein subunit beta 3	Homo sapiens	19-23
10693867-8	2000	The correlation between TNFalpha and Ag KS was positive in RA and negative in OA.	Potassium	40-42	tumor necrosis factor	Homo sapiens	24-32
10693867-9	2000	Further, in RA, OSM and IL-6 levels correlated strongly with Pyr and Ag KS levels but not with D-Pyr levels, while there were no strong correlations in OA for OSM or IL-6 levels with Pyr, Ag Ks, or D-Pyr levels.	Potassium	72-74	interleukin 6	Homo sapiens	24-28
10642604-7	2000	Membrane depolarization with gramicidin or by a high-potassium buffer was without effects on the lectin-mediated calcium release from intracellular stores but inhibited the gal-1 induced receptor-operated calcium influx.	Potassium	53-62	galectin 1	Homo sapiens	173-178
10718910-0	2000	Growth hormone-releasing hormone decreases voltage-gated potassium currents in GH4C1 cells.	Potassium	57-66	growth hormone releasing hormone	Rattus norvegicus	0-32
10652014-5	2000	Specifically, NBC-1 may be up-regulated in metabolic acidosis and potassium depletion and in response to glucocorticoid excess and may be down-regulated in response to HCO3- loading or alkalosis.	Potassium	66-75	solute carrier family 4 member 4	Homo sapiens	14-19
10652037-10	2000	No significant differences were found between the effects of losartan 100 mg and enalapril 20 mg. HbA1C and sodium intake remained unchanged throughout the study, whereas a significant rise in serum potassium occurred during ACE inhibition.	Potassium	199-208	angiotensin I converting enzyme	Homo sapiens	225-228
11971171-2	2000	Blockage of Ba(2+) on IRK1 (1 ms after voltage applied) is Ba(2+) concentration (0,1,3,10 or 100 micromol/L) dependent with 10 or 90 mmol/L potassium and also voltage-dependent.	Potassium	140-149	potassium inwardly rectifying channel subfamily J member 2 L homeolog	Xenopus laevis	22-26
10646604-2	2000	KCNQ1 (KvLQT1) interacts with the beta-subunit KCNE1 (IsK, minK) to form the slow, depolarization-activated potassium current I(Ks) that is affected in some forms of cardiac arrhythmia.	Potassium	128-130	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	0-5
11971173-4	2000	The results showed that rhHGF could protect hepatocytes against CCl4 through preventing intracellular ALT and potassium ion leakage, thus suggesting a synergistic effect of rhHGF and EGF on cytoprotection, and high expression of HGF and its receptor/c-met mRNA in the liver treated with PH and CCl4 poisoning.	Potassium	110-119	hepatocyte growth factor	Rattus norvegicus	26-29
11450063-9	2000	rCBF was inversely correlated with glutamate, lactate and potassium.	Potassium	58-67	CCAAT/enhancer binding protein zeta	Rattus norvegicus	0-4
10617665-2	2000	The retinal rod Na/Ca-K exchanger (NCKX) is a unique calcium extrusion protein utilizing both inward sodium gradient and outward potassium gradient.	Potassium	129-138	solute carrier family 24 member 1	Homo sapiens	35-39
10617665-4	2000	Here, we describe a simple system for quantitative analysis of NCKX function; stable transformation of cultured insect cells with the novel pEA1/153A vector containing NCKX cDNAs was combined with measurements of potassium-dependent (45)Ca uptake in sodium-loaded cells.	Potassium	213-222	solute carrier family 24 member 1	Homo sapiens	63-67
10617665-6	2000	We conclude that the potassium binding site is highly conserved among members of the NCKX family and is formed by residues located within the two sets of transmembrane spanning segments in the NCKX sequence.	Potassium	21-30	solute carrier family 24 member 1	Homo sapiens	85-89
10617665-6	2000	We conclude that the potassium binding site is highly conserved among members of the NCKX family and is formed by residues located within the two sets of transmembrane spanning segments in the NCKX sequence.	Potassium	21-30	solute carrier family 24 member 1	Homo sapiens	193-197
10769924-2	2000	A previous study from our laboratories revealed that HE, induced in rats by repeated treatment with thioacetamide, enhanced the 50 mM potassium (KCl)-stimulated release of newly loaded [3H]dopamine in both striatal and frontal cerebral cortical slices in the presence of Ca2+.	Potassium	134-143	carbonic anhydrase 2	Rattus norvegicus	271-274
10620287-1	2000	The voltage-gated potassium channel KCNQ1 associates with the small KCNE1 subunit to form the cardiac IKs delayed rectifier potassium current and mutations in both genes can lead to the long QT syndrome.	Potassium	18-27	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	36-41
10845107-4	2000	Activation of renal receptors by uroguanylin stimulates urine flow and excretion of sodium, chloride, and potassium.	Potassium	106-115	guanylate cyclase activator 2B	Homo sapiens	33-44
10620287-1	2000	The voltage-gated potassium channel KCNQ1 associates with the small KCNE1 subunit to form the cardiac IKs delayed rectifier potassium current and mutations in both genes can lead to the long QT syndrome.	Potassium	18-27	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	68-73
10620287-4	2000	Inward tail currents of homomeric KCNQ1 channels are increased about threefold upon substitution of 100 mM potassium with 100 mM rubidium despite a smaller rubidium permeability, suggesting an effect of rubidium on gating.	Potassium	107-116	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	34-39
11688957-4	2000	Tat is an angiogenic factor able to induce the migration and invasion of endothelial and KS cells through the interaction of its basic domain with the VEGF receptor VEGFR2 (Flk-1/KDR).	Potassium	89-91	vascular endothelial growth factor A	Homo sapiens	151-155
10656523-0	2000	Roles of calcium- and voltage-sensitive potassium currents in the generation of neuromagnetic signals and field potentials in a CA3 longitudinal slice of the guinea-pig.	Potassium	40-49	carbonic anhydrase 3	Cavia porcellus	128-131
11688957-4	2000	Tat is an angiogenic factor able to induce the migration and invasion of endothelial and KS cells through the interaction of its basic domain with the VEGF receptor VEGFR2 (Flk-1/KDR).	Potassium	89-91	kinase insert domain receptor	Homo sapiens	165-171
11688957-4	2000	Tat is an angiogenic factor able to induce the migration and invasion of endothelial and KS cells through the interaction of its basic domain with the VEGF receptor VEGFR2 (Flk-1/KDR).	Potassium	89-91	kinase insert domain receptor	Homo sapiens	173-178
11688957-4	2000	Tat is an angiogenic factor able to induce the migration and invasion of endothelial and KS cells through the interaction of its basic domain with the VEGF receptor VEGFR2 (Flk-1/KDR).	Potassium	89-91	kinase insert domain receptor	Homo sapiens	179-182
10644882-8	2000	CONCLUSION: These results suggest that adaptations to a high-potassium or a low-sodium diet and to metabolic acidosis involve decreases in renal 11betaHSD2 activity, enhancing the access of glucocorticoids to renal corticosteroid receptors.	Potassium	61-70	hydroxysteroid 11-beta dehydrogenase 2	Rattus norvegicus	145-155
10618149-7	2000	Sustained outward potassium currents, recorded in both whole-cell and outside-out patch configurations, demonstrated a selective reduction of amplitude only in antisense-treated CA1 pyramidal neurones.	Potassium	18-27	carbonic anhydrase 1	Rattus norvegicus	178-181
10627595-0	2000	Ribozyme-mediated inhibition of caspase-3 protects cerebellar granule cells from apoptosis induced by serum-potassium deprivation.	Potassium	108-117	caspase 3	Homo sapiens	32-41
10672584-5	2000	By P11, there are additional, non-reversible, changes in intracellular potassium and energy metabolites (ATP and phosphocreatine).	Potassium	71-80	endonuclease, poly(U) specific	Homo sapiens	3-6
10765111-5	2000	RESULTS: ICV injections of ANG II and ANG III at 5 pmol in rats on a normal sodium diet did not significantly alter the blood pressure, but significantly increased renal plasma flow, glomerular filtration rate, urine flow, and absolute and fractional excretions of sodium and potassium.	Potassium	276-285	angiotensinogen	Rattus norvegicus	27-33
11068335-8	2000	In PC12 cells, after 5-10 minutes of high potassium (75 mM) stimulation in the presence of HRP, SNAP-25 labeling appeared, additionally, on HRP-filled early endosomes.	Potassium	42-51	synaptosome associated protein 25	Rattus norvegicus	96-103
10704718-2	2000	Basal and potassium-stimulated NPY release from hypothalamic slices was not significantly altered by the addition of recombinant murine leptin.	Potassium	10-19	neuropeptide Y	Mus musculus	31-34
11008179-0	2000	Nerve growth factor maintains potassium conductance after nerve injury in adult cutaneous afferent dorsal root ganglion neurons.	Potassium	30-39	nerve growth factor	Homo sapiens	0-19
11008179-1	2000	Whole-cell patch-clamp techniques were used to study the effects of nerve growth factor on voltage-dependent potassium conductance in normal and axotomized identified large cutaneous afferent dorsal root ganglion neurons (48-50 micrometer diameter) many of which probably give rise to myelinated Abeta fibers.	Potassium	109-118	nerve growth factor	Homo sapiens	68-87
10749582-10	2000	Finally, AP-trasfected KS-IMM cells had significantly reduced migration to VEGF and HGF with respect to controls.	Potassium	23-25	vascular endothelial growth factor A	Homo sapiens	75-79
10749582-10	2000	Finally, AP-trasfected KS-IMM cells had significantly reduced migration to VEGF and HGF with respect to controls.	Potassium	23-25	hepatocyte growth factor	Homo sapiens	84-87
10704718-3	2000	However, the melanocortin-4 agonists, alpha-MSH and MT-II, significantly inhibited potassium-stimulated NPY release (p &lt; 0.01) without significantly altering basal NPY release.	Potassium	83-92	proopiomelanocortin	Rattus norvegicus	38-47
10704718-3	2000	However, the melanocortin-4 agonists, alpha-MSH and MT-II, significantly inhibited potassium-stimulated NPY release (p &lt; 0.01) without significantly altering basal NPY release.	Potassium	83-92	neuropeptide Y	Rattus norvegicus	104-107
10704730-5	2000	However, we were able to measure a significant reduction in potassium-stimulated NPY release (-60%) by using the nonselective voltage-dependent calcium channel blocker NiCl (30 microM) without any effect on basal release, as a positive control.	Potassium	60-69	neuropeptide Y	Homo sapiens	81-84
10651007-6	1999	The results are consistent with the presence of an IK1-type inwardly rectifying potassium conductance in these cells.	Potassium	80-89	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	Mus musculus	51-54
10720105-1	2000	Treatment with the angiotensin-converting enzyme inhibitor, quinapril, has been shown to normalize increased dihydropyridine sensitivity and impaired potassium relaxation, characteristic features of arterial smooth muscle in spontaneously hypertensive rats, and also reduce the concentration of plasma digoxin-like immunoreactivity in these animals.	Potassium	150-159	angiotensin I converting enzyme	Rattus norvegicus	19-48
10646192-1	1999	Connexin 26 (Cx26) is an inner ear protein that forms part of the potassium recycling pathway used to maintain the osmotic balance essential for normal auditory function.	Potassium	66-75	gap junction protein beta 2	Homo sapiens	0-11
10646192-1	1999	Connexin 26 (Cx26) is an inner ear protein that forms part of the potassium recycling pathway used to maintain the osmotic balance essential for normal auditory function.	Potassium	66-75	gap junction protein beta 2	Homo sapiens	13-17
10855836-3	1999	Comparing the phase of water restriction only with that of water restriction plus ACE inhibition, significant increases were observed during the latter phase in urine volume, sodium and potassium excretion via the urine, sodium concentration in the plasma and osmolar clearance.	Potassium	186-195	angiotensin-converting enzyme	Ovis aries	82-85
10619572-3	1999	The ability of ACE inhibitors to stabilize renal function is not attenuated by more severe renal insufficiency, but greater caution with these drugs is necessary, as there may be drug accumulation and a greater propensity for an increase in serum potassium and creatinine levels.	Potassium	247-256	angiotensin I converting enzyme	Homo sapiens	15-18
10656225-7	1999	It had been known since 1923 that insulin lowered serum potassium, but this was not of great interest because the symptoms of hypokalaemia were not known.	Potassium	56-65	insulin	Homo sapiens	34-41
10819495-1	1999	Theoretical background has been reviewed for inward rectification due to a potassium current termed IRK.	Potassium	75-84	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	100-103
10819495-2	1999	The Eyring rate theory in which the thermodynamic rate coefficient for chemical reactants (channels and ions in this case) can be described in terms of energy barriers for potassium ions can mimic not only the polarity and degree of rectification but also the voltage-dependence of the barium-induced IRK block.	Potassium	172-181	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	301-304
10559257-1	1999	Mutations in the gene encoding ether-a-go-go (EAG) potassium channel impair the function of several classes of potassium currents, synaptic transmission, and learning in Drosophila.	Potassium	51-60	ether a go-go	Drosophila melanogaster	46-49
10619653-5	1999	Depolarization by potassium or veratridine also induced GTPCH expression, which was abolished by EGTA.	Potassium	18-27	NGG1 interacting factor 3 like 1	Bos taurus	56-61
10581415-10	1999	The early response in PTEN mRNA expression disappeared in 5.5-kb transcripts already at 12 h and in the case of 2.5-kb transcripts it lasted up to 24 h. Potassium deprivation, known to induce apoptosis in cerebellar granule cells, did not affect PTEN mRNA expression but together with serum deprivation induced a clear decrease in the 5.	Potassium	153-162	phosphatase and tensin homolog	Mus musculus	22-26
10564240-9	1999	Human leptin caused a delayed diuresis/natriuresis (P &lt; 0.0006 and P &lt; 0.0049, respectively) that required approximately 2 h to achieve a maximum effect and that was not accompanied by changes in blood pressure or potassium excretion.	Potassium	220-229	leptin	Homo sapiens	6-12
10559257-1	1999	Mutations in the gene encoding ether-a-go-go (EAG) potassium channel impair the function of several classes of potassium currents, synaptic transmission, and learning in Drosophila.	Potassium	51-60	ether a go-go	Drosophila melanogaster	31-44
10559257-2	1999	Absence of EAG abolishes the modulation of a broad group of potassium currents.	Potassium	60-69	potassium voltage-gated channel subfamily H member 1	Homo sapiens	11-14
10542201-3	1999	The rubidium (potassium congener)-occluded enzyme (approximately 1.7 mol of rubidium/mol of alpha-chain) completely lost rubidium on the addition of sodium + magnesium.	Potassium	14-23	Fc gamma receptor and transporter	Homo sapiens	92-103
10581415-10	1999	The early response in PTEN mRNA expression disappeared in 5.5-kb transcripts already at 12 h and in the case of 2.5-kb transcripts it lasted up to 24 h. Potassium deprivation, known to induce apoptosis in cerebellar granule cells, did not affect PTEN mRNA expression but together with serum deprivation induced a clear decrease in the 5.	Potassium	153-162	phosphatase and tensin homolog	Mus musculus	246-250
10545508-4	1999	We show that NCKX30C functions as a potassium-dependent sodium/calcium exchanger, and is not only expressed in adult neurons as was expected, but is also expressed during ventral nerve cord development in the embryo and in larval imaginal discs.	Potassium	36-45	Nckx30C	Drosophila melanogaster	13-20
10537138-1	1999	Secretin is a 27-amino acid long peptide hormone that regulates pancreatic water, bicarbonate, enzymes, and potassium ion secretion.	Potassium	108-117	secretin	Homo sapiens	0-8
10502268-7	1999	Immunohistochemistry using anti-ORF59 rabbit antibodies revealed that this protein was expressed in some of the tumor cells found in KS tissues and that ORF59 protein was detected in 11 of 22 (50%) AIDS-KS tissues.	Potassium	133-135	ORF59	Human gammaherpesvirus 8	32-37
10576480-0	1999	Roles of a potassium afterhyperpolarization current in generating neuromagnetic fields and field potentials in longitudinal CA3 slices of the guinea-pig.	Potassium	11-20	carbonic anhydrase 3	Cavia porcellus	124-127
10559438-5	1999	Transgenic tobacco plants expressing CAX1 displayed symptoms of Ca(2+) deficiencies, including hypersensitivity to ion imbalances, such as increased magnesium and potassium concentrations, and to cold shock, but increasing the Ca(2+) in the media abrogated these sensitivities.	Potassium	163-172	cation exchanger 1	Arabidopsis thaliana	37-41
10516122-0	1999	Potassium control of extrarenal renin secretion in transgenic (mRen-2)27 and normal rats.	Potassium	0-9	renin	Rattus norvegicus	32-37
33867679-5	1999	Hence, CD222 and lifetime-based sensing can be used to measure blood levels of potassium in the presence of 130 mM sodium.	Potassium	79-88	insulin like growth factor 2 receptor	Homo sapiens	7-12
33867679-7	1999	For both CD222 and PBFI, the presence of blood levels of sodium increases the apparent potassium dissociation constants into the blood physiological range.	Potassium	87-96	insulin like growth factor 2 receptor	Homo sapiens	9-14
10537109-4	1999	Here we show that NF-ATc4/NF-AT3 in hippocampal neurons can rapidly translocate from cytoplasm to nucleus and activate NF-AT-dependent transcription in response to electrical activity or potassium depolarization.	Potassium	187-196	nuclear factor of activated T cells 4	Homo sapiens	18-25
10537109-4	1999	Here we show that NF-ATc4/NF-AT3 in hippocampal neurons can rapidly translocate from cytoplasm to nucleus and activate NF-AT-dependent transcription in response to electrical activity or potassium depolarization.	Potassium	187-196	nuclear factor of activated T cells 4	Homo sapiens	26-32
10537109-4	1999	Here we show that NF-ATc4/NF-AT3 in hippocampal neurons can rapidly translocate from cytoplasm to nucleus and activate NF-AT-dependent transcription in response to electrical activity or potassium depolarization.	Potassium	187-196	nuclear factor of activated T cells 4	Homo sapiens	18-23
10555144-5	1999	Cells expressing TOK1 exhibit toxin-induced potassium flux; those without the gene do not.	Potassium	44-53	Tok1p	Saccharomyces cerevisiae S288C	17-21
10535413-8	1999	These results suggest that both AT1 and AT2 receptor subtypes in the PVN are involved in ANG II-related urine, sodium, and potassium excretion, and that the inhibitory responses to AT2 blockade are predominant.	Potassium	123-132	angiotensin II receptor, type 1a	Rattus norvegicus	32-35
10535413-8	1999	These results suggest that both AT1 and AT2 receptor subtypes in the PVN are involved in ANG II-related urine, sodium, and potassium excretion, and that the inhibitory responses to AT2 blockade are predominant.	Potassium	123-132	angiotensin II receptor, type 2	Rattus norvegicus	40-43
10535413-8	1999	These results suggest that both AT1 and AT2 receptor subtypes in the PVN are involved in ANG II-related urine, sodium, and potassium excretion, and that the inhibitory responses to AT2 blockade are predominant.	Potassium	123-132	angiotensinogen	Rattus norvegicus	89-95
10516122-2	1999	In Ren-2 rats, active renin and prorenin increased with plasma potassium post-BNx and were augmented by potassium infusion.	Potassium	63-72	renin	Rattus norvegicus	22-27
10516122-2	1999	In Ren-2 rats, active renin and prorenin increased with plasma potassium post-BNx and were augmented by potassium infusion.	Potassium	104-113	renin	Rattus norvegicus	22-27
10516122-8	1999	The unidentified source of active renin in BNx+BADRx Ren-2 rats is also potassium and stress related.	Potassium	72-81	renin	Rattus norvegicus	34-39
10516123-3	1999	Secretion of active renin from these sites correlated significantly with increasing plasma potassium.	Potassium	91-100	renin	Rattus norvegicus	20-25
10471809-0	1999	Tpr1, a Schizosaccharomyces pombe protein involved in potassium transport.	Potassium	54-63	tetratricopeptide repeat domain 1	Mus musculus	0-4
10548063-8	1999	In the presence of saturating magnesium, potassium, and MgADP, the apparent rate constant for the release of EcDHFR from wild-type GroEL at 22 degrees C reaches a limiting value of 0.014 s(-1).	Potassium	41-50	GroEL	Escherichia coli	131-136
10548063-0	1999	Cooperative effects of potassium, magnesium, and magnesium-ADP on the release of Escherichia coli dihydrofolate reductase from the chaperonin GroEL.	Potassium	23-32	chaperonin GroEL	Escherichia coli	131-147
10548063-2	1999	In this paper, we investigate the effects of potassium, magnesium, and MgADP on the release of the EcDHFR late folding intermediate from GroEL.	Potassium	45-54	dihydrofolate reductase	Escherichia coli	99-105
10548063-2	1999	In this paper, we investigate the effects of potassium, magnesium, and MgADP on the release of the EcDHFR late folding intermediate from GroEL.	Potassium	45-54	GroEL	Escherichia coli	137-142
10548063-5	1999	Magnesium and potassium both shift the distribution of GroEL forms toward the form with the slower release rate, though cooperativity for the magnesium-induced transition is observed only in the presence of potassium.	Potassium	14-23	GroEL	Escherichia coli	55-60
10548063-6	1999	MgADP at low concentrations (0-50 microM) shifts the distribution of GroEL forms toward the form with the faster release rate, and this effect is also potassium dependent.	Potassium	151-160	GroEL	Escherichia coli	69-74
10548063-8	1999	In the presence of saturating magnesium, potassium, and MgADP, the apparent rate constant for the release of EcDHFR from wild-type GroEL at 22 degrees C reaches a limiting value of 0.014 s(-1).	Potassium	41-50	dihydrofolate reductase	Escherichia coli	109-115
10517637-5	1999	Here we show that polycystin-L is a calcium-modulated nonselective cation channel that is permeable to sodium, potassium and calcium ions.	Potassium	111-120	polycystic kidney disease 2-like 1	Mus musculus	18-30
10471809-1	1999	The Schizosaccharomyces pombe Tpr1 was isolated as suppressor of the Saccharomyces cerevisiae Delta trk1,2 potassium uptake deficient phenotype.	Potassium	107-116	tetratricopeptide repeat domain 1	Mus musculus	30-34
10471809-1	1999	The Schizosaccharomyces pombe Tpr1 was isolated as suppressor of the Saccharomyces cerevisiae Delta trk1,2 potassium uptake deficient phenotype.	Potassium	107-116	Trk1p	Saccharomyces cerevisiae S288C	100-104
10510183-5	1999	The potassium thiocyanate-stabilized binding of cyclophilin D to mouse brain mitochondrial membranes was completely prevented by cyclosporin A and N-Me-Val-4-cyclosporin A.	Potassium	4-13	peptidylprolyl isomerase F (cyclophilin F)	Mus musculus	48-61
10473656-10	1999	The results in KS, as compared with K562, confirm that wild-type p53 can prevent further cycling of polyploid cells by blocking rereplication.	Potassium	15-17	tumor protein p53	Homo sapiens	65-68
10510456-10	1999	6 In conclusion, HERG channel inhibition by cisapride exhibits features consistent with open and inactivated state binding and is sensitive to external potassium concentration.	Potassium	152-161	potassium voltage-gated channel subfamily H member 2	Homo sapiens	17-21
10536641-10	1999	Potassium depletion caused brush-border membrane NHE-3 protein abundance to rise, but only in the young rats.	Potassium	0-9	solute carrier family 9 member A3	Rattus norvegicus	49-54
10569256-8	1999	It is proposed that increased insulin secretory capacity associated with correction of negative potassium balance may account for the increase in plasma leptin after curing primary aldosteronism.	Potassium	96-105	leptin	Homo sapiens	153-159
10511387-2	1999	Elevation of extracellular potassium concentration within the physiological range inhibited free radical formation from macrophages and endothelial cells, inhibited proliferation and thymidine incorporation of vascular smooth muscle cells, and reduced platelet sensitivity to thrombin and other agonists.	Potassium	27-36	prothrombin	Oryctolagus cuniculus	276-284
10449752-6	1999	In KS-IMM cells Figf/Vegf-D treatment results in dose-dependent mitogenic and motogenic activities.	Potassium	3-5	vascular endothelial growth factor D	Homo sapiens	21-27
10465342-3	1999	We previously reported that the P-selectin-CD24 binding pathway is important for the binding of the breast carcinoma cell line KS to platelets and the rolling of these cells on endothelial P-selectin.	Potassium	127-129	selectin P	Homo sapiens	32-42
10465342-3	1999	We previously reported that the P-selectin-CD24 binding pathway is important for the binding of the breast carcinoma cell line KS to platelets and the rolling of these cells on endothelial P-selectin.	Potassium	127-129	CD24 molecule	Homo sapiens	43-47
10439465-2	1999	Depolarization of brain slices with NMDA or potassium produced a prolonged elevation of neuronal calcium signal in neurons in brain slices from calbindin D28k-deficient transgenic mice.	Potassium	44-53	calbindin 1	Mus musculus	144-158
10428953-8	1999	Owing to allosteric interactions, stilbene and fenamate compounds can rescue the dominant-negative suppression of I(KS) produced by IsK mutations and thus, may have important therapeutic relevance for LQT syndrome.	Potassium	116-118	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	132-135
10440258-0	1999	Thrombin inhibits active sodium-potassium transport in porcine lens.	Potassium	32-41	coagulation factor II, thrombin	Homo sapiens	0-8
10440258-2	1999	In the present study, experiments were conducted to determine the influence of thrombin on active sodium-potassium transport in porcine lenses.	Potassium	105-114	coagulation factor II, thrombin	Homo sapiens	79-87
10440258-13	1999	The functional significance of the thrombin-mediated change of lens active sodium-potassium transport is unclear since appreciable amounts of thrombin may only be presented to the lens during instances of blood-aqueous-barrier breakdown.	Potassium	82-91	coagulation factor II, thrombin	Homo sapiens	35-43
10440258-5	1999	RESULTS: In the presence of thrombin (1 unit/ml) the rate of ouabain-sensitive potassium (86Rb) uptake was reduced by 40% to 60%, but ouabain-insensitive potassium (86Rb) uptake was unchanged.	Potassium	79-88	coagulation factor II, thrombin	Homo sapiens	28-36
10440258-5	1999	RESULTS: In the presence of thrombin (1 unit/ml) the rate of ouabain-sensitive potassium (86Rb) uptake was reduced by 40% to 60%, but ouabain-insensitive potassium (86Rb) uptake was unchanged.	Potassium	154-163	coagulation factor II, thrombin	Homo sapiens	28-36
10440258-6	1999	The inhibitory effect of thrombin on ouabain-sensitive potassium (86Rb) uptake was suppressed in the presence of hirudin (an antagonist for thrombin receptors) but persisted in the presence of amphotericin B (a pseudo ionophore that effectively clamps plasma membrane sodium permeability at a high value).	Potassium	55-64	coagulation factor II, thrombin	Homo sapiens	25-33
10440258-6	1999	The inhibitory effect of thrombin on ouabain-sensitive potassium (86Rb) uptake was suppressed in the presence of hirudin (an antagonist for thrombin receptors) but persisted in the presence of amphotericin B (a pseudo ionophore that effectively clamps plasma membrane sodium permeability at a high value).	Potassium	55-64	coagulation factor II, thrombin	Homo sapiens	140-148
10412026-1	1999	The calcium (Ca2+) dependence of potassium (K+) efflux activated by hyposmolarity in cultured cerebellar astrocytes was investigated, measuring in parallel experiments (86)Rb release and changes in cytosolic Ca2+ ([Ca2+]i).	Potassium	33-42	carbonic anhydrase 2	Homo sapiens	13-16
10428060-3	1999	High-potassium stimulation (60 mM) of the slices produced a calcium-dependent threefold increase in NPY release above basal release.	Potassium	5-14	neuropeptide Y	Rattus norvegicus	100-103
10428041-0	1999	The survival of sympathetic neurons promoted by potassium depolarization, but not by cyclic AMP, requires phosphatidylinositol 3-kinase and Akt.	Potassium	48-57	AKT serine/threonine kinase 1	Homo sapiens	140-143
10428041-3	1999	We have tested PI 3-kinase and Akt for their role in survival promoted by membrane-depolarizing concentrations of extracellular potassium and the cell-permeable cyclic AMP analogue 8-(4-chlorophenylthio)cyclic AMP (cpt-cAMP).	Potassium	128-137	AKT serine/threonine kinase 1	Homo sapiens	31-34
10409754-3	1999	Using potassium permanganate, which preferentially modifies single-stranded DNA, we show that a temperature-sensitive rad25(ts) mutant severely reduces the normally extensive promoter melting observed in vivo on the highly expressed genes TDH2 and PDC1 and on the induced heat shock gene HSP82.	Potassium	6-15	TFIIH/NER complex ATPase/helicase subunit SSL2	Saccharomyces cerevisiae S288C	118-123
10409754-3	1999	Using potassium permanganate, which preferentially modifies single-stranded DNA, we show that a temperature-sensitive rad25(ts) mutant severely reduces the normally extensive promoter melting observed in vivo on the highly expressed genes TDH2 and PDC1 and on the induced heat shock gene HSP82.	Potassium	6-15	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2	Saccharomyces cerevisiae S288C	239-243
10419518-7	1999	Furthermore, maintaining a normal intracellular potassium concentration represses the cell death process by inhibiting the activity of apoptotic nucleases and suppressing the activation of effector caspases (Hughes, F. M., Jr., Bortner, C. D. Purdy, G. D., and Cidlowski, J.	Potassium	48-57	caspase 8	Homo sapiens	198-206
10434016-0	1999	Nitric oxide activates a potassium current in olfactory receptor neurons from Caudiverbera caudiverbera and Xenopus laevis.	Potassium	25-34	olfactory receptor	Xenopus laevis	46-64