PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 17191919-9 2005 Indirubin-5-5"-dicarbonitrile was also modified to the corresponding 3"-oxime, which had low specificity but showed very high inhibition of all three kinases with IC50 values of 5, 13, and 10 nM towards GSK-3alpha/beta, CDK1, and CDK5, respectively. indirubin-5-5"-dicarbonitrile 0-29 glycogen synthase kinase 3 alpha Homo sapiens 203-213 17191919-9 2005 Indirubin-5-5"-dicarbonitrile was also modified to the corresponding 3"-oxime, which had low specificity but showed very high inhibition of all three kinases with IC50 values of 5, 13, and 10 nM towards GSK-3alpha/beta, CDK1, and CDK5, respectively. indirubin-5-5"-dicarbonitrile 0-29 cyclin dependent kinase 1 Homo sapiens 220-224 17191919-9 2005 Indirubin-5-5"-dicarbonitrile was also modified to the corresponding 3"-oxime, which had low specificity but showed very high inhibition of all three kinases with IC50 values of 5, 13, and 10 nM towards GSK-3alpha/beta, CDK1, and CDK5, respectively. indirubin-5-5"-dicarbonitrile 0-29 cyclin dependent kinase 5 Homo sapiens 230-234