PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11467525-0	2001	Controlled nucleation and growth of surface-confined gold nanoparticles on a (3-aminopropyl)trimethoxysilane-modified glass slide: a strategy for SPR substrates.	3-aminopropyltrimethoxysilane	77-108	sepiapterin reductase	Homo sapiens	146-149
17559310-3	2007	The test compound used was the metabotropic glutamate receptor antagonist, L(+)-2-amino-3-phosphonopropionic acid (L-AP3), which is known to be toxic in vivo after subchronic, but not acute, administration.	3-aminopropyltrimethoxysilane	75-113	leucine aminopeptidase 3	Rattus norvegicus	115-120
11160821-9	2001	These data indicate that a homo-oligomeric form of Vps41p is required for the formation of ALP containing vesicles at the Golgi complex via interactions with AP-3.	3-aminopropyltrimethoxysilane	158-162	VPS41 subunit of HOPS complex	Homo sapiens	51-57
11160821-9	2001	These data indicate that a homo-oligomeric form of Vps41p is required for the formation of ALP containing vesicles at the Golgi complex via interactions with AP-3.	3-aminopropyltrimethoxysilane	158-162	alkaline phosphatase, placental	Homo sapiens	91-94
9845247-2	1998	The formation of lamellar bodies by t-ACPD or by anoxia was blocked by pretreatment of L(+)-2-amino-3-phosphonopropionic acid (L-AP3), which is an antagonist for the metabotropic glutamate receptor.	3-aminopropyltrimethoxysilane	87-125	leucine aminopeptidase 3	Rattus norvegicus	127-132
10723057-7	1999	As a control, the group I antagonists, L(+)-2-amino-3-phosphonopropionic acid (L-AP3) and (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA), prevented DHPG release of iCa(2+) but were ineffective against iCa(2+) release by 1S,3R-ACPD.	3-aminopropyltrimethoxysilane	39-77	leucine aminopeptidase 3	Homo sapiens	79-84
10723057-7	1999	As a control, the group I antagonists, L(+)-2-amino-3-phosphonopropionic acid (L-AP3) and (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA), prevented DHPG release of iCa(2+) but were ineffective against iCa(2+) release by 1S,3R-ACPD.	3-aminopropyltrimethoxysilane	39-77	homer scaffold protein 2	Homo sapiens	226-230
8624110-4	1996	The mGluR antagonist, L(+)-2-amino-3-phosphonopropionic acid (L-AP3), and GF 109203X, an inhibitor of PKC, both blocked the release of APPs from hippocampal neurons and astrocytes evoked by glutamate receptor stimulation.	3-aminopropyltrimethoxysilane	22-60	leucine aminopeptidase 3	Rattus norvegicus	62-67
9564031-6	1998	These results identify an LV-based sorting signal in the ALP cytoplasmic domain that directs transport into a clathrin-independent, AP-3-dependent pathway to the vacuole.	3-aminopropyltrimethoxysilane	132-136	alkaline phosphatase, placental	Homo sapiens	57-60
7981632-4	1994	The action of 1S,3R-ACPD was blocked by L(+)-2-amino-3-phosphonopropionic acid (L-AP3) a specific antagonist of the metabotropic glutamate receptor coupled to the hydrolysis of phosphoinositides and was reduced by 70% by preincubation of the slices with pertussis toxin.	3-aminopropyltrimethoxysilane	40-78	leucine aminopeptidase 3	Rattus norvegicus	80-85
8101213-9	1993	Moreover, this increase in survival was blocked by L-AP3 [L(+)-2-amino-3-phosphonopropionic acid; 1 microM], a putative antagonist of certain metabotropic responses.	3-aminopropyltrimethoxysilane	58-96	leucine aminopeptidase 3	Homo sapiens	51-56
1679224-2	1991	We have also found that pairing of synaptic activity with postsynaptic hyperpolarization is sufficient to induce LTD. We report here that 2-amino-3-phosphonopropionate (AP3), a selective inhibitor of phosphoinositide (PI) turnover mediated by the metabotropic glutamate receptor, blocks the induction of associative LTD in hippocampal field CA1, but does not impair the induction of LTP.	3-aminopropyltrimethoxysilane	169-172	carbonic anhydrase 1	Rattus norvegicus	341-344
33458480-3	2021	The results showed that the yield of lactic acid from Scenedesmus was greatly increased after being catalyzed by 3-aminopropyltrimethoxysilane (APTMS)-modified Sn-beta.	3-aminopropyltrimethoxysilane	113-142	snail family transcriptional repressor 1	Homo sapiens	160-167
34417312-3	2021	We demonstrate this 2D-EVSFG technique by investigating photoexcited interface-active (E)-4-((4-(dihexylamino) phenyl)diazinyl)-1-methylpyridin-1- lum (AP3) molecules at the air-water interface as an example.	3-aminopropyltrimethoxysilane	152-155	lumican	Homo sapiens	147-150
35142761-2	2022	Amino-mesoporous silica nanoparticles (MSN-NH2) were first synthesized by a simple co-condensation method using tetraethyl orthosilicate and 3-aminopropyltrimethoxysilane.	3-aminopropyltrimethoxysilane	141-170	moesin	Homo sapiens	39-42
33458480-3	2021	The results showed that the yield of lactic acid from Scenedesmus was greatly increased after being catalyzed by 3-aminopropyltrimethoxysilane (APTMS)-modified Sn-beta.	3-aminopropyltrimethoxysilane	144-149	snail family transcriptional repressor 1	Homo sapiens	160-167
25036662-1	2014	4-Aminophenazone (Ap-1) Schiff bases i.e., 4-{(3,4,5-trimethoxybenzylidine) amino}phenazone (Ap-2), 4-{(2-chlorobenzylidine) amino}phenazone (Ap-3) and 4-{(4-chlorobenzylidine)amino} phenazone (Ap-4) were synthesized and characterized by different spectroscopic techniques.	3-aminopropyltrimethoxysilane	142-146	FosB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	18-22
29022718-2	2017	In this work, we demonstrated a solution-based molecular layer deposition (MLD) approach to prepare porphyrin-based covalent organic molecular networks on a 3-aminopropyl trimethoxysilane (APTMS) modified substrate surface using the urea coupling reaction between 1,4-phenylene diisocyanate (1,4-PDI) and 5,10,15,20-tetrakis-(4-aminophenyl) porphyrin (H2TAPP) at room temperature (22 +- 2  C).	3-aminopropyltrimethoxysilane	157-187	peptidyl arginine deiminase 1	Homo sapiens	296-299
31666209-0	2020	New effective 3-aminopropyltrimethoxysilane functionalized magnetic sporopollenin-based silica coated graphene oxide adsorbent for removal of Pb(II) from aqueous environment.	3-aminopropyltrimethoxysilane	14-43	submaxillary gland androgen regulated protein 3B	Homo sapiens	142-148
31666209-1	2020	A new effective adsorbent, 3-aminopropyltrimethoxysilane functionalized magnetic sporopollenin (MSp@SiO2NH2) based silica-coated graphene oxide (GO), (GO@SiO2-MSp@SiO2NH2) was successfully synthesized and applied for the first time in the removal of hazardous Pb(II) ions from aqueous solution.	3-aminopropyltrimethoxysilane	27-56	submaxillary gland androgen regulated protein 3B	Homo sapiens	260-266
27968708-9	2017	Additionally, the down-regulation of p-Akt1 and up-regulation of cytochrome c, induced by OGD, were recovered to some extent after DL-AP3 treatment (p < 0.05 or p < 0.001).	3-aminopropyltrimethoxysilane	131-137	cytochrome c, somatic	Homo sapiens	65-77
26921503-2	2016	In this study, we firstly quantitatively analyzed the binding efficiency of (3-aminopropyl) trimethoxysilane (APTES) modified onto the surface of GOx.	3-aminopropyltrimethoxysilane	76-108	hydroxyacid oxidase 1	Homo sapiens	146-149
23055726-3	2012	An amine-terminated surface silanizing agent (3-aminopropyltrimethoxysilane) was used to functionalize the SiO(2) surface, which provides abundant -NH(2) functional groups for conjugating with tPA.	3-aminopropyltrimethoxysilane	46-75	plasminogen activator, tissue	Mus musculus	193-196
22640474-5	2012	RESULTS: Here we demonstrated that DL-AP3, a Grp1 mGluR antagonist, rescued LTP facilitation by D1 receptor agonist SKF81297 in Fmr1KO mice.	3-aminopropyltrimethoxysilane	35-41	glutamine repeat protein 1	Mus musculus	45-49
22640474-5	2012	RESULTS: Here we demonstrated that DL-AP3, a Grp1 mGluR antagonist, rescued LTP facilitation by D1 receptor agonist SKF81297 in Fmr1KO mice.	3-aminopropyltrimethoxysilane	35-41	dopamine receptor D1	Mus musculus	96-107
22640474-9	2012	However, simultaneous treatment of DL-AP3 could rescue the level of p-NR2B-Tyr1472 by SKF81297 in the cultures from KO mice.	3-aminopropyltrimethoxysilane	35-41	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	70-74
24501423-1	2014	As early endosomes mature, the SAND-1/CCZ-1 complex acts as a guanine nucleotide exchange factor (GEF) for RAB-7 to promote the activity of its effector, HOPS, which facilitates late endosome-lysosome fusion and the consumption of AP-3-containing vesicles.	3-aminopropyltrimethoxysilane	231-235	Vacuolar fusion protein MON1 homolog	Caenorhabditis elegans	31-37
24501423-1	2014	As early endosomes mature, the SAND-1/CCZ-1 complex acts as a guanine nucleotide exchange factor (GEF) for RAB-7 to promote the activity of its effector, HOPS, which facilitates late endosome-lysosome fusion and the consumption of AP-3-containing vesicles.	3-aminopropyltrimethoxysilane	231-235	Uncharacterized protein	Caenorhabditis elegans	38-43
24501423-1	2014	As early endosomes mature, the SAND-1/CCZ-1 complex acts as a guanine nucleotide exchange factor (GEF) for RAB-7 to promote the activity of its effector, HOPS, which facilitates late endosome-lysosome fusion and the consumption of AP-3-containing vesicles.	3-aminopropyltrimethoxysilane	231-235	RAB family	Caenorhabditis elegans	107-112
21482264-7	2011	Also compared were the performances of glucose biosensors with GOx immobilized on mesoporous SiO(2) by physical adsorption and by covalent binding to 3-aminopropyltrimethoxysilane (APTMS) modified SiO(2) using glutaraldehyde as the cross-linker.	3-aminopropyltrimethoxysilane	181-186	hydroxyacid oxidase 1	Homo sapiens	63-66
21683568-8	2011	The vacant places surrounding Mb were filled by polymerization of the silane monomers 3-aminopropyltrimethoxysilane (APTMS) and propyltrimethoxysilane (PTMS).	3-aminopropyltrimethoxysilane	86-115	myoglobin	Homo sapiens	30-32
21683568-8	2011	The vacant places surrounding Mb were filled by polymerization of the silane monomers 3-aminopropyltrimethoxysilane (APTMS) and propyltrimethoxysilane (PTMS).	3-aminopropyltrimethoxysilane	117-122	myoglobin	Homo sapiens	30-32
23144738-5	2012	Rabip4" colocalized with AP-3 on a tubular subdomain of early endosomes and the extent of colocalization was increased by a dominant negative rab4 mutant.	3-aminopropyltrimethoxysilane	25-29	RUN and FYVE domain containing 1	Homo sapiens	0-6
23144738-5	2012	Rabip4" colocalized with AP-3 on a tubular subdomain of early endosomes and the extent of colocalization was increased by a dominant negative rab4 mutant.	3-aminopropyltrimethoxysilane	25-29	RAB4A, member RAS oncogene family	Homo sapiens	142-146
19428785-6	2009	To investigate the binding mode of BLOC-1 and the AP-3 complex, we examined the relation between Dysbindin and the AP-3 complex and found that Dysbindin formed a complex with the AP-3 complex through the direct binding to its mu subunit.	3-aminopropyltrimethoxysilane	50-54	dystrobrevin binding protein 1	Mus musculus	143-152
19948346-1	2010	MCM-41 was grafted with 3-aminopropyl trimethoxysilane (APTMS), 3-chloropropyltriethoxysilane (CPTMS) to give organic group modified samples, and l-tryptophane was covalently immobilized onto organic samples to improve the physicochemical properties of mesoporous silica to controlled amoxicillin delivery.	3-aminopropyltrimethoxysilane	24-54	methylmalonyl-CoA mutase	Homo sapiens	0-3
19948346-1	2010	MCM-41 was grafted with 3-aminopropyl trimethoxysilane (APTMS), 3-chloropropyltriethoxysilane (CPTMS) to give organic group modified samples, and l-tryptophane was covalently immobilized onto organic samples to improve the physicochemical properties of mesoporous silica to controlled amoxicillin delivery.	3-aminopropyltrimethoxysilane	56-61	methylmalonyl-CoA mutase	Homo sapiens	0-3
19428785-6	2009	To investigate the binding mode of BLOC-1 and the AP-3 complex, we examined the relation between Dysbindin and the AP-3 complex and found that Dysbindin formed a complex with the AP-3 complex through the direct binding to its mu subunit.	3-aminopropyltrimethoxysilane	115-119	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	Mus musculus	35-41
19428785-6	2009	To investigate the binding mode of BLOC-1 and the AP-3 complex, we examined the relation between Dysbindin and the AP-3 complex and found that Dysbindin formed a complex with the AP-3 complex through the direct binding to its mu subunit.	3-aminopropyltrimethoxysilane	115-119	dystrobrevin binding protein 1	Mus musculus	143-152
19428785-6	2009	To investigate the binding mode of BLOC-1 and the AP-3 complex, we examined the relation between Dysbindin and the AP-3 complex and found that Dysbindin formed a complex with the AP-3 complex through the direct binding to its mu subunit.	3-aminopropyltrimethoxysilane	115-119	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	Mus musculus	35-41
19428785-6	2009	To investigate the binding mode of BLOC-1 and the AP-3 complex, we examined the relation between Dysbindin and the AP-3 complex and found that Dysbindin formed a complex with the AP-3 complex through the direct binding to its mu subunit.	3-aminopropyltrimethoxysilane	115-119	dystrobrevin binding protein 1	Mus musculus	143-152
19428785-9	2009	Thus, Dysbindin appears to participate in the exocytosis or sorting of the synaptic vesicle via direct interaction with the AP-3 complex.	3-aminopropyltrimethoxysilane	124-128	dystrobrevin binding protein 1	Mus musculus	6-15
20353220-3	2009	The CMCS-SPIONs were prepared by conjugating (carboxymethyl)chitosan to (3-aminopropyl)trimethoxysilane-treated SPIONs.	3-aminopropyltrimethoxysilane	72-103	G protein signaling modulator 2	Homo sapiens	4-8
19064117-1	2009	Two dioctadecyl L-glutamic acid derivatives with amide and ester type bondings have been synthesized and immobilized from 3-aminopropyltrimethoxysilane (APS) grafted silica (Sil-APS) to be used in reversed-phase high-performance liquid chromatography (RP-HPLC).	3-aminopropyltrimethoxysilane	122-151	STIL centriolar assembly protein	Homo sapiens	174-177
19064117-1	2009	Two dioctadecyl L-glutamic acid derivatives with amide and ester type bondings have been synthesized and immobilized from 3-aminopropyltrimethoxysilane (APS) grafted silica (Sil-APS) to be used in reversed-phase high-performance liquid chromatography (RP-HPLC).	3-aminopropyltrimethoxysilane	153-156	STIL centriolar assembly protein	Homo sapiens	174-177