PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
3522736-6	1986	High mannose oligosaccharides are added to the Mac-1 alpha and beta polypeptide backbones of Mr = 130,000 and 72,000, respectively, to yield precursors of Mr = 164,000 and 91,000, respectively.	mannose oligosaccharides	5-29	integrin alpha M	Mus musculus	47-58
6417140-7	1983	The intracellular hCG subunit precursors in both control and monensin-treated cells contained a similar array of high mannose oligosaccharides, predominantly of the Man8GlcNAc2 and Man9GlcNAc2 types.	mannose oligosaccharides	118-142	chorionic gonadotropin subunit beta 5	Homo sapiens	18-21
2420791-6	1986	Like the membrane-bound ER alpha-mannosidase, the soluble alpha-mannosidase can hydrolyze alpha-linked mannose from both p-nitrophenyl alpha-mannoside (Km = 0.14 mM) and high mannose oligosaccharides, is not inhibited by the mannose analogues swainsonine and 1-deoxymannojirimycin, is stabilized by MnCl2 or CoCl2, and does not bind to concanavalin A-Sepharose.	mannose oligosaccharides	175-199	estrogen receptor 1	Rattus norvegicus	24-32
7391040-0	1980	Biosynthetic intermediates of beta-glucuronidase contain high mannose oligosaccharides with blocked phosphate residues.	mannose oligosaccharides	62-86	glucuronidase beta	Homo sapiens	30-48
6223628-5	1983	The secreted cathepsin D, as well as that remaining within the cells, contains mostly high-mannose oligosaccharides cleavable with endo-beta-N-acetylglucosaminidase H. After removal of cyanate, the accumulated precursor forms of the lysosomal enzymes are largely released from the pretreated cells.	mannose oligosaccharides	91-115	cathepsin D	Homo sapiens	13-24
6251056-0	1980	Identification of a rat liver alpha-N-acetylglucosaminyl phosphodiesterase capable of removing "blocking" alpha-N-acetylglucosamine residues from phosphorylated high mannose oligosaccharides of lysosomal enzymes.	mannose oligosaccharides	166-190	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	Homo sapiens	30-74
6848519-7	1983	High mannose oligosaccharides are abundant in the monensin-derived fibronectin, whereas the control protein contains primarily complex oligosaccharides.	mannose oligosaccharides	5-29	fibronectin 1	Homo sapiens	67-78
6848519-8	1983	Monensin apparently does not alter the initial glycosylation of fibronectin since the high mannose oligosaccharides are present on both control and monensin-treated intracellular fibronectin.	mannose oligosaccharides	91-115	fibronectin 1	Homo sapiens	179-190
7358675-2	1980	The role of high mannose oligosaccharides in the hepatic uptake of IgM .	mannose oligosaccharides	17-41	immunoglobulin heavy chain 6	Rattus norvegicus	67-70
7358675-13	1980	These data suggest that antigen-induced conformational changes can result in exposure of high mannose oligosaccharides on IgM which signal the clearance of soluble immune complexes from the circulation.	mannose oligosaccharides	94-118	immunoglobulin heavy chain 6	Rattus norvegicus	122-125
31907993-6	2020	Unusual glycan epitopes identified on CD11b/CD18 included high Mannose oligosaccharides recognized by the Galanthus Nivalis lectin and biantennary galactosylated N-glycans recognized by the Phaseolus Vulgaris erythroagglutinin lectin.	mannose oligosaccharides	63-87	integrin subunit alpha M	Homo sapiens	38-43
20181944-6	2010	Glycan array screening with the trimeric fragment shows that high mannose oligosaccharides are the best ligands for langerin.	mannose oligosaccharides	66-90	CD207 molecule	Homo sapiens	116-124
28824637-7	2017	Furthermore, the BCR in chronic lymphocytic leukemia (CLL) carries high-mannose oligosaccharides, albeit in the heavy chain constant rather than variable region.	mannose oligosaccharides	72-96	BCR activator of RhoGEF and GTPase	Homo sapiens	17-20
22893705-9	2012	Analysis of the Asn-linked oligosaccharides showed that MT2 cleavage of cell surface HJV was coupled to a transition from high mannose oligosaccharides to complex oligosaccharides on HJV.	mannose oligosaccharides	127-151	transmembrane serine protease 6	Homo sapiens	56-59
22893705-9	2012	Analysis of the Asn-linked oligosaccharides showed that MT2 cleavage of cell surface HJV was coupled to a transition from high mannose oligosaccharides to complex oligosaccharides on HJV.	mannose oligosaccharides	127-151	hemojuvelin BMP co-receptor	Homo sapiens	85-88
21298103-1	2011	Malectin is a conserved, endoplasmic reticulum (ER)-resident lectin that recognizes high mannose oligosaccharides displaying terminal glucose residues.	mannose oligosaccharides	89-113	malectin	Homo sapiens	0-8
31766009-0	2020	Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN.	mannose oligosaccharides	59-83	mannose receptor C-type 1	Homo sapiens	108-124
29104323-2	2017	Two representative branched mannose oligosaccharides, a mannose heptasaccharide (Man7) and a mannose nonasaccharide (Man9) were constructed via (4+3) and (5+4) glycosylations, respectively.	mannose oligosaccharides	28-52	mannosidase alpha class 1A member 1	Homo sapiens	117-121
25912189-6	2015	RESULTS: In this study, we show that CL-K1 primarily targets a subset of high-mannose oligosaccharides present on both self- and non-self structures, and provide the structural basis for its ligand specificity.	mannose oligosaccharides	78-102	collectin subfamily member 11	Homo sapiens	37-42
25912189-11	2015	CONCLUSIONS: We have established the sugar specificity of CL-K1 and demonstrated that it targets high-mannose oligosaccharides on self- and non-self structures via an extended binding site which recognises the terminal two mannose residues of the carbohydrate ligand.	mannose oligosaccharides	102-126	collectin subfamily member 11	Homo sapiens	58-63
24440421-4	2014	The macrophage mannose receptor (MMR, CD206), a C-type lectin receptor, is ubiquitously expressed on macrophages and has a high affinity for mannose oligosaccharides.	mannose oligosaccharides	141-165	ATPase, class II, type 9B	Mus musculus	33-36
24440421-4	2014	The macrophage mannose receptor (MMR, CD206), a C-type lectin receptor, is ubiquitously expressed on macrophages and has a high affinity for mannose oligosaccharides.	mannose oligosaccharides	141-165	mannose receptor, C type 1	Mus musculus	38-43
19903812-2	2010	2G12 adopts a unique variable heavy domain-exchanged dimeric configuration that results in an extensive multivalent binding surface and the ability to bind with high affinity to densely clustered high mannose oligosaccharides on the "silent" face of the gp120 envelope glycoprotein.	mannose oligosaccharides	201-225	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	254-259
20018892-2	2010	Firstly, due to its ability to bind monoglucosylated high mannose oligosaccharides, calreticulin is a central component of the folding quality control system of glycoproteins.	mannose oligosaccharides	58-82	calreticulin	Homo sapiens	84-96
19180724-2	2008	Teicoplanin and dalbavancin glycopeptide antibiotics possess N-acetyl glucosamine and mannose oligosaccharides that may bind MBL.	mannose oligosaccharides	86-110	mannose-binding lectin (protein C) 2	Mus musculus	125-128
19438409-7	2009	AE1 expressed in K562 cells contained both complex and high-mannose oligosaccharides, and co-localized with GPA at the cell surface and in the endoplasmic reticulum (ER).	mannose oligosaccharides	60-84	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	0-3
15302162-3	2004	Both the conventional and the unprecedented additional VH-VH antigen binding sites show specificity for high mannose oligosaccharides on the silent face of gp120.	mannose oligosaccharides	109-133	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	156-161
17084089-7	2007	This described approach was applied to two high mannose oligosaccharides M5G2, M6G2 cleaved from the ribonuclease B and a complex oligosaccharide A2 cleaved from transferrin.	mannose oligosaccharides	48-72	transferrin	Homo sapiens	162-173
17177443-12	2006	This modeling study provided detailed insight into the mechanism of the GlcNAc transfer catalyzed by GnT-I, which is the first step in the conversion of high mannose oligosaccharides to complex and hybrid N-glycan structures.	mannose oligosaccharides	158-182	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	101-106
16115860-3	2005	Substrate specificity studies comparing the novel human alpha-mannosidase with human LysMan revealed that the former enzyme efficiently cleaved only the alpha1-6mannose residue from Man(3)GlcNAc but not Man(3)GlcNAc(2) or other larger high mannose oligosaccharides, indicating a requirement for chitobiase action before alpha1,6-mannosidase activity.	mannose oligosaccharides	240-264	adrenoceptor alpha 1D	Homo sapiens	153-161
12626394-6	2003	Langerin extracellular domain binds mammalian high mannose oligosaccharides, as well mannose-containing structures on yeast invertase but does not bind complex glycan structures.	mannose oligosaccharides	51-75	CD207 molecule	Homo sapiens	0-8
12904308-6	2003	However, the ZPA N-linked glycans were composed of acidic-complex and high-mannose oligosaccharides, ZPX had only high-mannose oligosaccharides, and ZPB lacked N-linked oligosaccharides.	mannose oligosaccharides	75-99	zzona pellucida glycoprotein 2 L homeolog	Xenopus laevis	13-16
11404356-7	2001	In addition, synthetic high mannose oligosaccharides can block TNF-VSG interactions, and a VSG glycopeptide carrying the GlcNAc(2)-Man(5-9) moiety is shown to inhibit TNF-mediated trypanosome killing in mixed parasite/macrophage cell cultures.	mannose oligosaccharides	28-52	tumor necrosis factor	Homo sapiens	63-66
12054763-3	2002	CVN selectively binds with nanomolar affinity the mammalian high mannose oligosaccharides oligomannose-8 D1D3 and oligomannose-9, which also govern binding to gp120.	mannose oligosaccharides	65-89	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	159-164
10715554-13	2000	Thus truncated hFSH-R variants do not reach the medial or trans Golgi where high mannose oligosaccharides are trimmed and sialic acid is added.	mannose oligosaccharides	81-105	follicle stimulating hormone receptor	Homo sapiens	15-21
9572291-9	1998	Procathepsin E, after pulse-labeling, showed complete susceptibility to endoglycosidase H, whereas the mature enzyme almost acquired resistance to endoglycosidases H as well as F. The present studies provide the first evidence that cathepsin E in microglia is first synthesized as the inactive precursor bearing high-mannose oligosaccharides and processed to the active mature enzyme with complex-type oligosaccharides via the intermediate form and that the final proteolytic maturation step occurs in endosome-like acidic compartments.	mannose oligosaccharides	317-341	cathepsin E	Rattus norvegicus	3-14
10580131-5	1999	The alpha-glucosidases participate in glycoprotein folding mediated by calnexin and calreticulin by forming the monoglucosylated high mannose oligosaccharides required for the interaction with the chaperones.	mannose oligosaccharides	134-158	calnexin	Homo sapiens	71-79
10580131-5	1999	The alpha-glucosidases participate in glycoprotein folding mediated by calnexin and calreticulin by forming the monoglucosylated high mannose oligosaccharides required for the interaction with the chaperones.	mannose oligosaccharides	134-158	calreticulin	Homo sapiens	84-96
10514470-0	1999	Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor.	mannose oligosaccharides	56-80	mannose-6-phosphate receptor, cation dependent	Bos taurus	88-133
10407159-3	1999	It cleaved alpha1-2 linked mannosyl residues and less but significantly cleaved alpha1-3 and alpha1-6 linked mannosyl residues in the high-mannose oligosaccharides.	mannose oligosaccharides	139-163	adrenoceptor alpha 1D	Homo sapiens	80-101
9748289-2	1998	The oligosaccharyltransferase (OST), which has its active site exposed on the luminal face of the endoplasmic reticulum (ER), catalyzes the transfer of preassembled high mannose oligosaccharides onto certain asparagine residues of nascent polypeptides.	mannose oligosaccharides	170-194	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	4-29
9748289-2	1998	The oligosaccharyltransferase (OST), which has its active site exposed on the luminal face of the endoplasmic reticulum (ER), catalyzes the transfer of preassembled high mannose oligosaccharides onto certain asparagine residues of nascent polypeptides.	mannose oligosaccharides	170-194	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	31-34
7545761-7	1995	Another difference was that a lower molecular weight form of MAG with predominantly high mannose oligosaccharides was prominent in young quaking mice, but not in controls.	mannose oligosaccharides	89-113	myelin-associated glycoprotein	Mus musculus	61-64
7545761-7	1995	Another difference was that a lower molecular weight form of MAG with predominantly high mannose oligosaccharides was prominent in young quaking mice, but not in controls.	mannose oligosaccharides	89-113	quaking, KH domain containing RNA binding	Mus musculus	137-144
8366110-9	1993	The secreted protein is then enriched in molecules bearing phosphorylated high mannose oligosaccharides in their lysozyme moiety.	mannose oligosaccharides	79-103	lysozyme	Homo sapiens	113-121
1385399-5	1992	Electrospray ionization-mass spectrometry demonstrates that high mannose oligosaccharides ((Man)nGlcNAc2, n = 5-9) are the only N-glycotypes occupying Asn65 when soluble CD2 is expressed in Chinese hamster ovary cells.	mannose oligosaccharides	65-89	CD2 molecule	Homo sapiens	170-173
2925680-3	1989	Class E Thy-1- cells produce truncated high mannose oligosaccharides that lack 4 mannose residues from the alpha 1,6-branch of the core beta-linked mannose residue; three of the missing residues are potential phosphorylation sites.	mannose oligosaccharides	44-68	thymus cell antigen 1, theta	Mus musculus	8-13
1523886-7	1992	The och1 mutant cells accumulated the external invertase containing a large amount of core-like oligosaccharides (Man9-10GlcNAc2) and a small amount of high mannose oligosaccharides (greater than Man50GlcNAc2) at the non-permissive temperature.	mannose oligosaccharides	157-181	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	4-8
1856221-13	1991	The retained lysozyme was recruited predominantly from the molecules bearing high mannose oligosaccharides.	mannose oligosaccharides	82-106	lysozyme	Homo sapiens	13-21
1922010-3	1991	Endometrial explants cultured in vitro secrete Uf with a Mr of 37,000 (37k Uf) having phosphorylated high mannose oligosaccharides.	mannose oligosaccharides	106-130	acid phosphatase 5, tartrate resistant	Sus scrofa	47-49
3069116-4	1988	The gp40 molecule was shown to have both complex and high-mannose oligosaccharides comprising some 16% of the apparent molecular weight.	mannose oligosaccharides	58-82	CD7 molecule	Homo sapiens	4-8
3034910-6	1987	Removal of high mannose oligosaccharides by endo-beta-N-acetylglucosaminidase H treatment reduced the apparent molecular weight of the 160-kDa precursor but did not affect the migration of the 180-kDa mature receptor.	mannose oligosaccharides	16-40	O-GlcNAcase	Homo sapiens	49-77